human embryonic stem cells human induced pluripotent stem cells yamanaka s. et al. cell 2007 thomson...

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Page 1: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 2: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Human embryonic stem cells

Page 3: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Human induced pluripotent stem cells

Yamanaka S. et al. Cell 2007Thomson J. et al. Science 2007

Page 4: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Proteomic comparison

14 days of analysis15,091 phosphorylation sites7,962 unique proteins

Page 5: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 6: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 7: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 8: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Multiplexed enrichment analysis

Page 9: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Chromatin Modifying Proteins

Note reversed scale

Page 10: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 11: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 12: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 13: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Protein-protein interactions

Page 14: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Protein-protein interactions

Becker, KA. et al Journal of Cellular Physiology 2007

Page 15: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Reprogramming networks

Page 16: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Cyclin-dependent kinase 2

Page 17: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

mRNA up , protein down

Page 18: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 19: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 20: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 21: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 22: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Kinase Analysis

Page 23: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 24: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 25: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 26: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 27: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 28: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 29: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

Page 30: Human embryonic stem cells Human induced pluripotent stem cells Yamanaka S. et al. Cell 2007 Thomson J. et al. Science 2007

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