how to analyse dust in the lung dr. med. andreas burger zentrum für medizinische lehre in der...
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How to analyse dust in the lung
Dr. med. Andreas Burger
Zentrum für Medizinische Lehre in der Medizinischen Fakultät der RUB (Center of Medical Education in the Faculty of Medicine)Lehrender des Institutes für Pathologie Ruhr-Universität Bochum(Teacher of the Institute of Pathology) Ruhr-University Bochum
Lecture Moscow 27.05.2010
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
That is the Problem:
A white lung
–Silikoses
–Asbestoses
–Hardmetalfibroses
–and so on
Lungdiseases conditional on dust
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
• Pulmonal Hypertonus (> 25 mm Hg or
• 325 kPa)
• Cor pulmonale – Hypertrophy – and/or– Insufficiency
of the right heart
• Also often causes obstruction
Complications
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
• Coal miners• Workers in casting• Gum manufacture• Welding• Coating• Working with Pesticids, Herbicids, Dioxin• Oilrefinerie• Cane-sugar manufacture
Professions with higher risks on lung diseases with dust
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
• Safe: Arsen, Asbest, Bichlormethylester, Chrome- u. Nickelcompounds, polyzyclic aromatic coal-hydrogens (pacs), Radon, venom gases
• Suspected: Cadmium, chlorined Toluoles, Dimethylsulfat, Epichlorhydrids, Mineral-fibres, Lead, Silicates, Talcum
• In question: Acrylnitrites, Beryllium, Vinyl-chloride
Dusts with higher risks for lung cancer
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
gross anatomy of the left lung
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
subpleural dust and emphysema
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Lungfibroses
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Microscopy
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Energy Dispersive X-Ray Analysis
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Asbestbodies
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Trans Electron Microscopy
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Trans-, Scanning Electron Microscopy
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Energy Dispersive X-Ray Analysis (Spectroscopy)
Ferric oxidehttp://de.wikipedia.org/wiki/Energiedispersive_R%C3%B6ntgenspektroskopie
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Energy Dispersive X-Ray Analysis
© http:// marl.iastate.edu
Liquid nitrogen
Analysis unit by Thermo Scientific – Kevex X-Ray Products320 El Pueblo RoadScotts Valley, CA 95066 USA
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Energy Dispersive X-Ray Analysis
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Dust Inflammation FibrosisWelding smoke in this case
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
• Gardolineum
Contrasting in angiographics
New Entity
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
White lung - lungfibrosis
• 26 year old man• Heroin disease• Heroin extended
with talcum
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
Talcum powder
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012
EDX-spectrum of Talcum Powder
© Dr. med. Andreas Burger 2012 How to analyse dust in the lung, lecture Irkutsk 15.10.2012