homoeopathic treatment of parkinson diese

8/7/2019 homoeopathic treatment of parkinson diese

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Parkinson's Disease

Introducon - Also called: Paralysis agitans, Shaking palsy

Parkinson's disease (also known as Parkinson disease or PD) is a degenerae disorder o! the

central nerous syste" that o#en i"pairs the su$erer's "otor skills and speech%

&istory

Sy"pto"s o! Parkinson's disease hae een known and treated since ancient "es% &oweer, it

was not !or"ally recognied and its sy"pto"s were not docu"ented unl *+, in An ssay on

the Shaking Palsy% y the rish physician .a"es Parkinson% Parkinson's disease was then known

as paralysis agitans, the ter" /Parkinson's disease/ eing coined later y .ean 0arn 1harcot%

2he underlying ioche"ical changes in the rain were iden3ed in the 456's, due largely to the

work o! Swedish scienst Arwid 1arlsson, who later went on to win a 7oel prie%

Discussion

Parkinson's disease is a disorder that a$ects nere cells, or neurons, in a part o! the rain that

controls "uscle "oe"ent% In Parkinson's, neurons that "ake a che"ical called dopa"ine die or

do not work properly% Dopa"ine nor"ally sends signals that help coordinate your "oe"ents%

Parkinson's is a disease that causes a progressie loss o! nere cell !uncon in the part o! the

rain that controls "uscle "oe"ent% Progressie "eans that this disease's e$ects get worse

oer "e%

Sy"pto"s o! Parkinson's Disease


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Parkinson's disease elongs to a group o! condions called "oe"ent disorders% 2he pri"ary

sy"pto"s are the results o! decreased s"ulaon o! the "otor corte8 y the asal ganglia,

nor"ally caused y the insu9cient !or"aon and acon o! dopa"ine ,which is produced in the

dopa"inergic neurons o! the rain% Secondary sy"pto"s "ay include high leel cogniedys!uncon and sutle language prole"s% PD is oth chronic and progressie%

PD is the "ost co""on cause o! parkinsonis" a group o! si"ilar sy"pto"s% PD is also called

/pri"ary parkinsonis"/ or /idiopathic PD/ (haing no known cause)% hile "ost !or"s o!

parkinsonis" are idiopathic, there are so"e cases where the sy"pto"s "ay result !ro" to8icity,

drugs, genec "utaon, head trau"a, or other "edical disorders%

arly sy"pto"s o! PD are sutle and occur gradually% A$ected people "ay !eel "ild tre"ors or

hae di9culty ge;ng out o! a chair% 2hey "ay noce that they speak too so#ly or that their

handwring is slow and looks cra"ped or s"all% 2hey "ay lose track o! a word or thought, or

they "ay !eel red, irritale, or depressed !or no apparent reason% 2his ery early period "ay

last a long "e e!ore the "ore classic and oious sy"pto"s appear%


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PD does not a$ect eeryone the sa"e way, and the rate o! progression di$ers a"ong paents%

2re"or is the "a=or sy"pto" !or so"e paents, while !or others? tre"or is none8istent or ery

"inor%

PD sy"pto"s o#en egin on one side o! the ody% &oweer, as it progresses, the disease

eentually a$ects oth sides% en a#er the disease inoles oth sides o! the ody, the

sy"pto"s are o#en less seere on one side than on the other%

2he !our pri"ary sy"pto"s o! PD are:

2re"or% 2he tre"or associated with PD has a characterisc appearance% 2ypically, the tre"or

takes the !or" o! a rhyth"ic ack-and-!orth "oon at a rate o! @- eats per second% It "ay

inole the thu" and !ore3nger and appear as a /pill rolling/ tre"or% 2re"or o#en egins in a

hand, although so"e"es a !oot or the =aw is a$ected 3rst% It is "ost oious when the hand is

at rest or when a person is under stress%


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shoulders are drooped%

A nu"er o! other sy"pto"s "ay acco"pany PD% So"e are "inor? others are not% 0any can e

treated with "edicaon or physical therapy% 7o one can predict which sy"pto"s will a$ect an

indiidual paent, and the intensity o! the sy"pto"s aries !ro" person to person%

Depression% 2his is a co""on prole" and "ay appear early in the course o! the disease,

een e!ore other sy"pto"s are noced%


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Skin prole"s% In PD, it is co""on !or the skin on the !ace to eco"e ery oily, parcularly

on the !orehead and at the sides o! the nose% 2he scalp "ay eco"e oily too, resulng in

dandru$% In other cases, the skin can eco"e ery dry% 2hese prole"s are also the result o! an

i"properly !unconing autono"ic nerous syste"% Standard treat"ents !or skin prole"s can

help% 8cessie sweang, another co""on sy"pto", is usually controllale with "edicaons

used !or PD%

Sleep prole"s% Sleep prole"s co""on in PD include di9culty staying asleep at night,

restless sleep, night"ares and e"oonal drea"s, and drowsiness or sudden sleep onset during

the day% Paents with PD should neer take oer-the-counter sleep aids without consulng their

physicians%

De"ena or other cognie prole"s% So"e, ut not all, people with PD "ay deelop"e"ory prole"s and slow thinking% In so"e o! these cases, cognie prole"s eco"e "ore

seere, leading to a condion called Parkinson's de"ena late in the course o! the disease% 2his

de"ena "ay a$ect "e"ory, social =udg"ent, language, reasoning, or other "ental skills%

Erthostac hypotension% Erthostac hypotension is a sudden drop in lood pressure when

a person stands up !ro" a lying-down posion% 2his "ay cause diiness, lightheadedness, and,

in e8tre"e cases, loss o! alance or !ainng% Studies hae suggested that, in PD, this prole"

results !ro" a loss o! nere endings in the sy"pathec nerous syste" that controls heart rate,

lood pressure, and other auto"ac !uncons in the ody% 2he "edicaons used to treat PD

also "ay contriute to this sy"pto"%

0uscle cra"ps and dystonia% 2he rigidity and lack o! nor"al "oe"ent associated with PD

o#en causes "uscle cra"ps, especially in the legs and toes% 0assage, stretching, and applying

heat "ay help with these cra"ps% PD also can e associated with dystonia C sustained "uscle

contracons that cause !orced or twisted posions% Dystonia in PD is o#en caused y

Huctuaons in the ody's leel o! dopa"ine% It can usually e relieed or reduced y ad=usng

the person's "edicaons%

Pain% 0any people with PD deelop aching "uscles and =oints ecause o! the rigidity and

anor"al postures o#en associated with the disease% 1ertain e8ercises also "ay help% People

with PD also "ay deelop pain due to co"pression o! nere roots or dystonia-related "uscle

spas"s% In rare cases, people with PD "ay deelop une8plained urning, staing sensaons%


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2his type o! pain, called /central pain,/ originates in the rain% Dopa"inergic drugs, opiates,

andepressants, and other types o! drugs "ay all e used to treat this type o! pain%


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s$ness, and in=uries associated with aGe"pts at acco""odaon

hat 1auses Parkinson's DiseaseK

2he "ain causes could e graded under !our headings:

Lenec

2o8ins

&ead in=ury

Drug induced

Parkinson's disease occurs when nere cells, or neurons, in an area o! the rain known as the

sustana nigra die or eco"e i"paired% 7or"ally, these neurons produce an i"portant rain

che"ical known as dopa"ine% Dopa"ine is a che"ical "essenger responsile !or trans"i;ng

signals etween the sustana nigra and the ne8t /relay staon/ o! the rain, the corpus

striatu", to produce s"ooth, purpose!ul "oe"ent% Moss o! dopa"ine results in anor"al

nere 3ring paGerns within the rain that cause i"paired "oe"ent% Studies hae shown that

"ost Parkinson's paents hae lost 6 to *6 percent or "ore o! the dopa"ine-producing cells in

the sustana nigra y the "e sy"pto"s appear% Becent studies hae shown that people with

PD also hae loss o! the nere endings that produce the neurotrans"iGer nor epinephrine% 7or

epinephrine, which is closely related to dopa"ine, is the "ain che"ical "essenger o! the

sy"pathec nerous syste", the part o! the nerous syste" that controls "any auto"ac

!uncons o! the ody, such as pulse and lood pressure% 2he loss o! nor epinephrine "ight help

e8plain seeral o! the non-"otor !eatures seen in PD, including !ague and anor"alies o!

lood pressure regulaon%

Sciensts hae iden3ed seeral genec "utaons associated with PD, and "any "ore geneshae een tentaely linked to the disorder% Studying the genes responsile !or inherited cases

o! PD can help researchers understand oth inherited and sporadic cases% 2he sa"e genes and

proteins that are altered in inherited cases "ay also e altered in sporadic cases y

eniron"ental to8ins or other !actors%


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Although the i"portance o! genecs in PD is increasingly recognied, "ost researchers eliee

eniron"ental e8posures increase a person's risk o! deeloping the disease% en in !a"ilial

cases, e8posure to to8ins or other eniron"ental !actors "ay inHuence when sy"pto"s o! the

disease appear or how the disease progresses% 2here are a nu"er o! to8ins, such as -"ethyl-@-

phenyl-, N, O, -tetrahydropyridine, or 0P2P (!ound in so"e kinds o! synthec heroin), that can

cause Parkinson Ian sy"pto"s in hu"ans% Ether, sll-uniden3ed eniron"ental !actors also

"ay cause PD in genecally susceple indiiduals%

iruses are another possile eniron"ental trigger !or PD% People who deeloped

encephalopathy a#er a 4* inHuena epide"ic were later stricken with seere, progressie

Parkinson's-like sy"pto"s% A group o! 2aiwanese wo"en deeloped si"ilar sy"pto"s a#er

contracng herpes irus in!econs% In these wo"en, the sy"pto"s, which later disappeared,

were linked to a te"porary inHa""aon o! the sustana nigra%

Seeral lines o! research suggest that "itochondria "ay play a role in the deelop"ent o! PD%

0itochondria are the energy-producing co"ponents o! the cell and are "a=or sources o! !ree

radicals C "olecules that da"age "e"ranes, proteins, D7A, and other parts o! the cell% 2his

da"age is o#en re!erred to as o8idae stress% E8idae stress-related changes, including !ree

radical da"age to D7A, proteins, and !ats, hae een detected in rains o! PD paents%

Ether research suggests that the cell's protein disposal syste" "ay !ail in people with PD,

causing proteins to uild up to har"!ul leels and trigger cell death% Addional studies hae

!ound eidence that clu"ps o! protein that deelop inside rain cells o! people with PD "ay

contriute to the death o! neurons, and that inHa""aon or oer s"ulaon o! cells (ecause

o! to8ins or other !actors) "ay play a role in the disease% &oweer, the precise role o! the

protein deposits re"ains unknown% So"e researchers een speculate that the protein uildup is

part o! an unsuccess!ul aGe"pt to protect the cell% hile "itochondrial dys!uncon, o8idae

stress, inHa""aon, and "any other cellular processes "ay contriute to PD, the actual cause

o! the dopa"ine cell death is sll undeter"ined%

&ow is Parkinson's Disease diagnosedK

A doctor "ay diagnose a person with Parkinson's disease ased on the paent's sy"pto"s,

neurological e8a"inaons and "edical history% 7o lood tests or 8-rays can show whether a

person has Parkinson's disease% &oweer, so"e kinds o! 8-rays can help the doctor "ake sure

nothing else is causing sy"pto"s% I! sy"pto"s go away or get eGer when the person takes a

"edicine called leodopa, it's !airly certain that he or she has Parkinson's disease%


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2he disease can e di9cult to diagnose accurately% 2he Fni3ed disease rang scale is the

pri"ary clinical tool used to assist in diagnosis and deter"ine seerity o! PD% Indeed, only +5Q o!

clinical diagnoses o! PD are con3r"ed at autopsy% arly signs and sy"pto"s o! PD "ay

so"e"es e dis"issed as the e$ects o! nor"al aging% 2he physician "ay need to osere the

person !or so"e "e unl it is apparent that the sy"pto"s are consistently present% Fsually

doctors look !or shuRing o! !eet and lack o! swing in the ar"s% Doctors "ay so"e"es re>uest

rain scans or laoratory tests in order to rule out other diseases% &oweer, 12 and 0BI rain

scans o! people with PD usually appear nor"al%

2he Fni3ed Parkinson's Disease Bang Scale (FPDBS) is a rang scale used to !ollow the

longitudinal course o! Parkinsons disease% It is "ade up o! the !ollowing secons:

0entaon, ehaior, and "ood?

Acies o! daily liing?

0otor?

1o"plicaons o! therapy?

&oehn and Tahr Stage?

&oehn and Tahr Staging o! Parkinson's Disease

Stage one

Sy"pto"s on one side o! the ody only%


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Stage two

Sy"pto"s on oth sides o! the ody% 7o i"pair"ent o! alance%

Stage three

alance i"pair"ent% 0ild to "oderate disease% Physically independent%

Stage !our

Seere disaility, ut sll ale to walk or stand unassisted%

Stage 3e

heelchair-ound or edridden unless assisted%

Prognosis o! Parkinsons disease%

PD is not y itsel! a !atal disease, ut it does get worse with "e% 2he aerage li!e e8pectancy o!

a PD paent is generally the sa"e as !or people who do not hae the disease% &oweer, in the

late stages o! the disease, PD "ay cause co"plicaons such as choking, pneu"onia, and !alls

that can lead to death% uickly% 2here is no way to predict what course the disease will take !or

an indiidual person%


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1an "edicines treat Parkinson's diseaseK

Allopathic treat"ent--

2here is no cure !or Parkinson's disease% ut "edicines can help control the sy"pto"s o! the

disease% So"e o! the "edicines used to treat Parkinson's disease include caridopa-leodopa

(one rand na"e: Sine"et), ro"ocripne (rand na"e: Parlodel), selegiline (one rand na"e:

ldepryl), pra"ipe8ole (rand na"e: 0irape8), ropinirole (rand na"e: Be>uip), and tolcapone

(rand na"e: 2as"ar)%

0edicaons to 2reat the 0otor Sy"pto"s o! Parkinson's disease

Drugs that increase rain leels o! dopa"ine

Meodopa

Drugs that "i"ic dopa"ine (dopa"ine agonists)

Apo"orphine

ro"ocripne

Pra"ipe8ole

Bopinirole

Drugs that inhiit dopa"ine reakdown (0AE- inhiitors)

Selegiline (deprenyl)

Drugs that inhiit dopa"ine reakdown (1E02 inhiitors)


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ntacapone

2olcapone

Drugs that decrease the acon o! acetylcholine ancholinergics)

2rihe8yphenidyl

entropine

thopropaine

Drugs with an unknown "echanis" o! acon !or PD

A"antadine

Side e$ects o! drugs used !or Parkinsons disease:

2he "ost co""on drugs used in the treat"ent are:

M-dopa J It is the "ost widely used drug ut also causes "any side e$ects ecause only -5Q o!

M-dopa enters dopa"inergic neurons rest is "etaolied to dopa"ine elsewhere%

Inially it causes co"plaints like:

7ausea

o"ing

Beduced lood pressure

Bestlessness

Drowsiness and sudden sleep


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Mater it can co"plicate the condion een !urther and can cause:

&allucinaons

Psychosis

Tounger paents o! Parkinsons su$er "ore !ro" its side e$ects as:

Dyskinesis

Pain!ul Uo$ dystonias

2re"ors intensi3ed

Dyskinesias, or inoluntary "oe"ents such as twitching, twisng, and writhing, co""only

deelop in people who take large doses o! leodopa oer an e8tended period% 2hese "oe"ents

"ay e either "ild or seere and either ery rapid or ery slow% 2he dose o! leodopa is o#en

reduced in order to lessen these drug-induced "oe"ents% &oweer, the PD sy"pto"s o#en

reappear een with lower doses o! "edicaon% Doctors and paents "ust work together closely

to 3nd a tolerale alance etween the drug's ene3ts and side e$ects%

2he period o! e$eceness a#er each dose "ay egin to shorten, called the wearing-o$ e$ect%

Another potenal prole" is re!erred to as the on-o$ e$ect C sudden, unpredictale changes in

"oe"ent, !ro" nor"al to Parkinson Ian "oe"ent and ack again% 2hese e$ects proaly

indicate that the paent's response to the drug is changing or that the disease is progressing%

Dopa"ine agonists -

So"nolence

&allucinaons

Inso"nia

Eede"a

Mess "otor Huctuaons

Dyskinesis (twisng V turning) "oe"ents


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In rare cases, they can cause co"pulsie ehaior, such as an uncontrollale desire to ga"le,

hyper se8uality, or co"pulsie shopping% ro"ocripne can also cause 3rosis, or a uildup o!

3rous ssue, in the heart ales or the chest caity%


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usually !or a rie! period and with only a O6 percent i"proe"ent% Side e$ects "ay include dry

"outh, conspaon, urinary retenon, hallucinaons, "e"ory loss, lurred ision, and

con!usion%

&o"eopathic 2reat"ent

&o"eopathy treats the person as a whole% It "eans that ho"eopathic treat"ent !ocuses on the

paent as a person, as well as his pathological condion% 2he ho"eopathic "edicines are

selected a#er a !ull indiidualiing e8a"inaon and case-analysis, which includes the "edical

history o! the paent, physical and "ental constuon etc% A "ias"ac tendency

(predisposionVsusceptaility) is also o#en taken into account !or the treat"ent o! chronic

condions% 2he "edicines gien elow indicate the therapeuc a9nity ut this is not a co"plete

and de3nite guide to the treat"ent o! this condion% 2he sy"pto"s listed against each "edicine

"ay not e directly related to this disease ecause in ho"eopathy general sy"pto"s and

constuonal indicaons are also taken into account !or selecng a re"edy% 2o study any o! the

!ollowing re"edies in "ore detail, please isit our 0ateria 0edica secon% 7one o! these

"edicines should e taken without pro!essional adice%

Beportorial ruric:

0urphy: Diseases: Paralysis-agitans%

1larke: Paralysis agitans%

oericke: 7erous syste": Paralysis-2ype - agitans

&o"eopathic Be"edies

Agar%, A" Lr%, Arg-n%, Aur%, u!o%,1occ%, 1on%, Lels%, &elo%, &yos% ,Mathyr%, 0ag-p%, 0B1%, 7u8-%,

Phos%, Pl%, Puls%, B&FS-2%, Sta"%, 2arent%, 2hu=%, WI71%,%

0ateria "edica


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0ercurius

eakness o! li"s, tre"ling o! e8tre"ies, especially hands% Paralyc agitans% Macerang pain

in =oints% 1old and cla""y sweat on li"s% Eily perspiraon% 2re"ors eerywhere in ody%

eakness with tre"ling !ro" least e8eron% All sy"pto"s are aggraated at night, war"th o!

ed, Da"p, cold, rainy weather and during perspiraon% 1o"plaints increase during sweang

and rest% All sy"pto"s always associated with weariness, prostraon and tre"ling%

Slow in answering >uesons% 0e"ory weakened and loss o! will power% Skin always "oist and

!reely perspiring% Itching worse war"th o! ed%

Wincu"-0etallicu"

iolent tre"ling (twitching) o! the whole ody especially a#er e"oons% 2witching in children%

1horea% Paralysis o! hands and !eet% 2re"ling o! hands while wring% Ma"eness, weakness,

tre"ling and twitching o! arious "uscles%


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in this re"edy, weakness and paralysis, especially o! the "uscles o! the head% Paralysis o! arious

groups o! "uscles like eyes, throat, chest, sphincters and e8tre"ies% &ead re"edy !or tre"ors%

0ind sluggish and "uscular syste" rela8ed% Staggering gait% Moss o! power o! "uscular control%

1ra"ps in "uscles o! !orear"% 8cessie tre"ling and weakness o! all li"s% orse y

da"pness, e8cite"ent, ad news% eGer y ending !orwards, pro!use urinaon, connued

"oon and open air%

Argentu" 7itricu"

It is co"pli"entary to Lelse"iu"% 0e"ory i"paired? easily e8cited and angered? Hatulence and

greenish diarrhea%Inco-ordinaon, loss o! control and i"alance with tre"ling and general

deility% Paralysis with "ental and ado"inal sy"pto"s% Bigidity o! cales% alks and stands

unsteadily% 7u"ness o! ody% Specially ar"s%

Agaricus 0uscarius

2re"ling, itching and =erking, s$ness o! "uscles? itching o! skin oer the a$ected parts and

e8tre"e sensieness o! the spine% 1annot ear touch% .erking and tre"ling are strong

indicaons% 1horea and twitching ceases during sleep% Paralysis o! lower li"s with spas"odic

condions o! ar"s% 7u"ness o! legs on crossing the"% Paralyc pain in le# ar" !ollowed y

palpitaon% S$ness all oer with pain oer hips%

1occulus

&ead tre"les while eang and when it is raised higher% Xnees sink down !ro" weakness% 2oGers

while walking with tendency to !all on one side% 1racking o! the knee when "oing% Ma"eness

worse y ending% 2re"ling and pain in li"s% Ene-sided paralysis worse a#er sleep% Intensely

pain!ul, paralyc drawing% Mi"s straightened out and pain!ul when He8ed%

It shows special a9nity !or light haired !e"ales especially during pregnancy%

Mathyrus


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19/23

0ag-phos

2re"ling? shaking o! hands, inoluntary% Paralysis agitans% 1ra"ps in cales, !eet ery tender%

2witching, 1horea, cra"ps% 7u"ness o! 3nger ps% orse right side, cold, touch, night% eGer

war"th, ending doule, pressure and !ricon%

u!o Bana

Special acon on nerous syste"% Pain!ul paralysis% Pain in loins, nu"ness and cra"ps%

Staggering gait%


20/23

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homoeopathic treatment of parkinson diese

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