HIV infection(AIDS)HIV infection(AIDS)

Dr. Yingguo DingDr. Yingguo Ding

Dept. of DermatologyDept. of Dermatology

First Affiliated HospitalFirst Affiliated Hospital

HIV infection(AIDS)HIV infection(AIDS)

Dr. Yingguo DingDr. Yingguo Ding

Dept. of DermatologyDept. of Dermatology

First Affiliated HospitalFirst Affiliated Hospital

Sexually transmitted Sexually transmitted diseasedisease

- Cutaneous manifestations - Cutaneous manifestations

and managementand management- Cutaneous manifestations - Cutaneous manifestations

and managementand management

PathogenesisPathogenesis

Human immunodeficiency virus (HIV) I type &II type

– isolated from blood, serum, genital secretions, breast milk, cerebrospinal fluid, urine, saliva and lacrimal fluid.

Main infection routes– Sexual activity– Blood infection(blood products transfusion, sharing

of needles for drugs, needle stick accidents)– Mother-to-child infection

MechanismMechanism

Infection Tumor Non-infectious

severe,atypical,bigotry

Cutaneous manifestations of AIDSCutaneous manifestations of AIDS

- three categories- three categories

InfectionInfection ：：

1. Oral hairy leukoplakia (OHL) ： 20 ％ Early specific sign EBV correlating Candida (+)

2.Viruse infections ： - Herpes zoster/Herpes simplex - CA ： giant

- Warts

- CMV

3.Fungi infections ： - Tinea - Candidiasis - Cryptococcosis 2 ％ 9 ％， multiformic ，

Cryptococcosis

4.Bacteria infections: - folliculitis,impetigo… - TB ： warty tuberculosis

Tumor:Tumor:

1.Kaposi’s sarcoma 30 ％ risk generalized progressive painful systemic

2.non-Hodgkin's lymphoma(NHL):

4 ％～ 10 ％

3.Other ： Mycosis Fungoides(MF) 、squamous cell carcinoma(SCC) 、basal cell carcinoma(BCC) 、 malignant melanoma(MM)…

1.Seborrheic dermatitis ： 70 ％～ 80 ％ , early stage

2.Psoriasis:

～ 5 ％， first sign, mark of poor prognosis

3.hair abnormalities:

alopecia,white hair,prolonged eyelashes…

4.Drug eruptions

Non-infectiousNon-infectious

Ichthyosiform lesions

There is no cure or vaccine for HIV yet.

Important ： epidemic prevention