hfr general presentation
TRANSCRIPT
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Since 1988 High Force Research has worked
with organizations operating in practically all end
use sectors requiring chemical synthesis input,
and offers a range of services allied to new
product development
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History
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Durham
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Meet the team
Chairman
Bob Redfern
CEO
Roy Valentine
Research Manager
Nicola Lembicz
Research Chemists
Development Manager
Barry Thompson
Development Chemists
Head of Quality
Zoe Lilburn
QA Department QC Department
Head of Business Development
Stella James
Marketing
Operations Director
Stuart Penny
GMP Chemists
• 30 staff, one third PhD’s
• Highly experienced team of chemists and analysts
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• Pharmaceutical
• Biotechnology
• Diagnostics
• Imaging
• Agrochemical
• Organic Electronics
• Performance materials
• Polymers
• Coatings
• Fine Chemicals
Who we work with
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• Multinationals
• SME’s
• Start-ups
• Spin-outs
• Virtual Enterprises
• Universities
• Charities
• Institutes
Who we work with
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• Chemical R&D
- milligram to kilo scale
• Process Development
- route design, development
& optimisation
- improve yields
- reduce the number of steps
- reduce batch cycle times
- eliminate the use of
hazardous materials
How we can help
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• Contract Synthesis
- Building blocks &
intermediates
- Patent analogues
- Non-literature targets
- Client proprietary
compounds
- Reference standards
- Drug impurity compounds
- Metabolites
How we can help
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• Scale-up
- gram to kilo
• Analysis
- analytical services and
method development
• Consultancy
How we can help
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• Traceable Manufacture
- Pre-clinical studies
- API starting materials
- Performance materials
• GMP (MHRA inspected)
- Analytical Development
- Validation
- Stability Studies
- Auditing
- Reference substances
How we can help
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• 1100 m2 of laboratory space
• 30 x Fume cupboards
• 2 x Class 8 clean rooms
• Jacketed glassware to 30L at -
40 to 180oC
• Pressure vessels to 7L
• Ability to handle HF
• Mass Spectrometry
Facilities
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• Multinuclear 400Mhz NMR
• HPLC (UV, DAD)
• FTIR (ATR)
• Karl Fischer
• DSC
• Classical wet analysis
• GLC (Liquid and Headspace)
• Size Exclusion Chromatography
• Optical rotation
Facilities
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• Elemental Analysis
• XRPD
• Solid State NMR
• Raman Spectroscopy
• Surface Analysis
- SEM,TEM, XRF etc.
• LC-ICP-MS
• Microbiology
Access to advanced techniques
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• For over 27 years, HFR has
supported the pharmaceutical
and chemical industry in their
medical and scientific advances
• Collaborate with companies at
the proof of concept stage of
their product or technology life
cycle
• Expert in developing and
scaling up complex syntheses
of molecules used by
researchers
Why choose HFR?
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• The only independently owned
UK business that works to GMP
on small scale production only
audited by the MHRA for early
stage clinical trials
• Flexible & adaptable approach
to chemical synthesis. Working
collaboratively to achieve the
highest quality compounds from
gram to kilo with products
delivered to specification, on-
time and safely
Why choose HFR?
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Contact us:
Head of Business Development
Stella James
+44 (0) 744 358 7141
www.highforceresearch.com