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Hepatitis C Surveillance and Epidemiology in New York City Angelica Bocour, MPH Director of Surveillance, Viral Hepatitis Program Bureau of Communicable Disease New York City Department of Health and Mental Hygiene

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Page 1: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Hepatitis C Surveillance and Epidemiology in New York City

Angelica Bocour, MPH

Director of Surveillance, Viral Hepatitis Program

Bureau of Communicable Disease

New York City Department of Health and Mental Hygiene

Page 2: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Hepatitis C Surveillance in NYC• High volume of reports 

• >200,000 hepatitis C labs• >90% of reports are imported electronically from labs

• Reportable hepatitis C tests: positive antibody, negative and positive RNA, genotype, ALTs reported if on same accession as a reportable lab• Not reportable: negative antibody, positive rapid antibody

• Surveillance Program Goals• Describe the epidemiology of chronic hepatitis C• Estimate prevalence in NYC

• 1.4% (116,000) New Yorkers with chronic hepatitis C (Bocour et al, Epidemiol & Infect, 2018)

• Monitor appropriate diagnostic testing, linkage to care and cure

Page 3: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Demographic Data from Laboratory Reports

Demographic information

received

•Name•Date of birth•Social security number•Sex•Age•Address•Phone number

Do not receive•Race/ethnicity•Country of birth•Risk factors

Page 4: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Acute Hepatitis C

Acute hepatitis C case finding:• Not reliably reported by providers• Without negative antibody test results, cannot identify seroconversions

• Currently identified through dialysis center reports and enhanced surveillance investigations

0

2

4

6

8

10

12

14

16

18

2008 2009 2010 2011 2012 2013 2014 2015 2016 2017

Num

ber o

f cases

Report Year

Number of reported confirmed acute hepatitis C cases, New York City 2008–2017

Page 5: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

People Newly Reported with Chronic Hepatitis C in NYC, 2008–2017

Page 6: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Confirmatory Testing for Chronic Hepatitis C Infection

• In 2017, 11,786 people were reported with a positive antibody test• 9,801 (83.2%) had confirmatory testing• Two‐thirds (66.1%) were antibody positive/RNA negative

• Two‐thirds (65.8%) had a reflex RNA test

• 5,308 were antibody or RNA positive

Antibody positive only, 

16.8%

RNA negative, 66.1%

RNA positive, 33.9%

RNA confirmation, 

83.2%

5,308people newly reported with chronic hepatitis C infection

Page 7: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Rates of People Newly Reported with Hepatitis C in NYC by Neighborhood*, 2017

*Neighborhood Tabulation Area: https://www1.nyc.gov/site/planning/data‐maps/open‐data/dwnnynta.page

Page 8: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Age Distribution of People Newly Reported with Chronic Hepatitis C in NYC, 2017

0

20

40

60

80

100

120

140

1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 35 37 39 41 43 45 47 49 51 53 55 57 59 61 63 65 67 69 71 73 75 77 79 81 83 85 87 89 91 93 95 97 99

Num

ber o

f peo

ple ne

wly re

ported

 

FEMALE MALE

Page 9: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Women of Childbearing Age (15‐44 years) Newly Reported with Chronic Hepatitis C

Page 10: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

People Ages 0 to 29 Newly Reported with Chronic Hepatitis C, NYC

Page 11: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Characteristics of People Newly Reported with Chronic Hepatitis C, 2017

Page 12: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Enhanced Chronic Hepatitis C Surveillance, July 2009‐October 2012

United States, 50.7%

Unknown, 31.0%

Other, 5.6%

Former Soviet Union, 

4.6%

Pakistan, 2.0%

Dominican Republic, 2.0%

Haiti, 1.6% China, 1.3%

Egypt, 1.0%

Latino, 30.7%

Black, non‐Latino, 30.1%

White, non‐Latino, 21.2%

Asian, non‐Latino, 5.6%

Other, 2.3%Unknown, 10.1%

Country of Birth Race/Ethnicity

Page 13: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Hepatitis C Care Cascade for NYC Residents*

*People reported to the NYC Health Department through June 30, 2017 with any hepatitis C test since July 1, 2014‐June 30, 2017**People with a positive antibody and only a negative RNA test are excluded from the first bar

Positive antibody test with no RNA or ever RNA positive**

Positive RNA, ever CuredInitiated treatment

Page 14: Hepatitis C Surveillance and Epidemiology in New York City...•Describe the epidemiology of chronic hepatitis C •Estimate prevalence in NYC •1.4% (116,000) New Yorkers with chronic

Viral Hepatitis ResourcesHepatitis A, B and C in New York City: 2017 Annual Report

https://www1.nyc.gov/assets/doh/downloads/pdf/cd/hepatitis‐abc‐annual‐report‐2017.pdf

nyc.gov/health/epiquery

Contact information:Angelica Bocour, MPHDirector of Viral Hepatitis SurveillanceBureau of Communicable DiseaseNYC Department of Health and Mental Hygiene42‐09 28th Street, 6th floorLong Island City, NY 11101Phone: 347‐396‐7614Email: [email protected]