hemodialysis and peritoneal dialysis

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DIALYSIS

DIALYSISAneez. KIst YEAR MSc. NURSINGEMS CON

Definition

Dialysis is the movement of fluid and molecules across a semipermeable membrane from one compartment to another. Clinically dialysis is a technique in which substances move from the blood through a semipermeable membrane and in to a dialysis solution called dialysate.

Historical Evolution in the Field Of Dialysis

It was the romans first used a form of dialysis therapy by using hot bath to patients to remove urea.

1854 the first time the term dialysis was used by Thomas Graham1889 BW Richardson First referred the use of collodion membrane in the dialysis of blood .This help the living animals were dialysed in experimental conditions.

1914 Hess & McGuigan were experimenting with dialysis in a pharmacology lab in Chicago. As a result they were able to transfer sugar from tissue to blood and from the blood across a collodion membrane.1920s the first dialysis performed on human was carried out by George Hass. He used hirudin as an anticoagulant and later a crude form of heparin. He was honoured as a pioneer of dialysis.

1923 Heinrich Necheles was discovered contemporary dialyser.In mid 1930s purification of the heparin occur.1937 an American scientist, William Thalhimer use first synthetic membrane.

In 1945 William Kolff first clinical experience was gained on a 29 year old women with chronic nephritis. The blood urea was kept stable for 26 days but after 12 sessions of dialysis her blood urea began to increase and she subsequently died.After the world war Kolff technique was wildly used.

In 1950s Allis Chalmers Corporation was one of the first companies to produce dialysis machine commercially.In the late 1950s Fredrik Kiil of Norway made more modification in the field of dialyser. In 1960s the forerunner of todays capillary flow dialyser was produced by Richard Stewart.Belding Scribner was introduced the shunt to provide vascular access in dialysis.

Followed by this invention hemodialysis started.In late 1970s and early 1980s the continuous ambulatory peritoneal dialysis as the first choice of home treatment. The innovations in the field of dialysis is reaching up to the satellite dialysing unit nowadays. And the patient surveillance rate also increase.

Principles of Dialysis

Diffusion: Diffusion is the movement of solutes from an area of greater concentration to an area of lower concentration.

Osmosis: Osmosis is the movement of fluid from an area of lesser concentration to an area of greater concentration of solutes.

Ultra filtration: Ultra filtration that is solution move when there is an osmotic gradient or pressure gradient across the membrane.

INDICATION OF DIALYSISRenal failure Severe electrolyte and/or fluid abnormalities AcidosisDrug overdose Poisoning

TYPES OF DIALYSIS

HEMODIALYSIS

PERITONEAL DIALYSIS

HEMODIALYSISHEMODIALYSIS APPARATUSBlood circuitDialysis solution circuitDialyser

BLOOD CIRCUTE

DIALYSIS SOLUTION CIRCUTEWater Purification System

RO + Acetic Acid + NaHCO3 + KHCO3

REVERSE OSMOSIS

DIALYSER

VASCULAR ACCESSIntravenous CatheterNon-tunnelled or Temporary CatheterTunnelled or Permanent Catheter or Prem CathAV fistulaAV graft

INTRAVENOUS CATHETERS

Replacement therapies of HDHEMOFILTRATIONHEMODIAFILTRATIONINTESTINAL DIALYSISPLASMAFERESIS

PERITONEAL DIALYSISFill phaseDwell phaseDrain phase

Complications of Peritoneal DialysisPeritonitisCatheter InfectionCuff erosionAbdominal herniasAbdominal distensionHypotension

HyperglycaemiaHypernatremia/ HypernatremiaHyperkalaemia/HypokalaemiaHypoalbuminemiaAbdominal wall and pericatheer leakGenital edemaRespiratory complicationsBack painDyslipidaemia

Psychosocial Issues in ESRD Patients

Psychological problems like,DepressionDementia/ DeliriumAnxiety and behaviour disorders

Psychosocial Issues like,

Marital relationshipSexual dysfunctionSocioeconomic issuesRehabilitationQuality of lifeAltered body imageAwareness of early deathNon adherence to the medical and nursing care

BIBLIOGRAPHY

John T. Daugirdas, Peter G. Blake, Todd S. Ing Handbook of Dialysis(2007),4th edition, Wolters Kluwer (India) publication, page no: 59-88Allen R. Nissenson, Richrad N. Fine Handbook of Dialysis Therapy (2009), 4th edition, Elsevier Publications, page no: 703-710, 1221-1225Nicola Thomas Renal Nursing (2008), 3rd edition, Elsevier Publication, page no: 73-78, 181-232Lewis, Dirksen, Heitkemper, Bucher Medical Surgical Nursing Assessment and Management of Clinical Problems (2011), 9th edition, Elsevier Publications, page no: 1183-1188Lippincott Manual of Nursing Practice (2009), 10th edition, Wolters Kluwer (India) publication, page no: 785-788http://en.wikipedia.org/wiki/Dialysishttp://www.ncbi.nlm.nih.gov/pubmed/22916962

THANK YOU

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