guoqiang yu, ph.d. - university of...

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1 Guoqiang Yu, Ph.D. Associate Professor Department of Biomedical Engineering (BME) University of Kentucky,Lexington, KY 40506-0070 Tel: 859-257-9110; Fax: 859-257-1856 Email: [email protected] ACADEMIC POSTIONS Department of Biomedical Engineering, University of Kentucky (UK), Lexington, KY, USA Associate Professor 2012- Assistant Professor 2007-2012 Physics & Astronomy, University of Pennsylvania, Philadelphia, PA, USA Research Assistant Professor 2006-2007 Senior Research Investigator 2004-2006 Research Associate 2002-2004 Postdoctoral Fellow 2001-2002 Physikalisch-Technische Bundesanstalt (PTB), Braunschweig, Germany Research Scientist 1999-2001 EDUCATION Biomedical Engineering, Tianjin University, Tianjin, China Ph.D. of Biomedical Engineering -1999 AWARDS AND HONORS Editorial Board Member: Senior editor board member for ―American Journal of Cancer Science‖ 2012- Associate editor for ―Journal of Biomedical Optics‖ 2012- Editorial board member of ―Open Journal of Clinical Diagnostics2012- Editorial board member of ―International Journal of Biomedical Engineering2012- Editorial board member of Spectroscopy: An International Journal2012- Editorial board member of Anatomy & Physiology2011- Editorial board member of Journal of Cancer Therapy2010- Reviewer for Grant and Faculty/Student Evaluation: Reviewer for COST-Switzerland office at the State Secretariat for Education, Research and Innovation SERI (Switzerland, 2013) Reviewer for American Association for the Advancement of Science Research Competitiveness Program in the review of proposals submitted for funding through the King Abdulaziz City for Science and Technology (2012) Reviewer for University of Wisconsin-Milwaukee (UWM) Research Foundation (Wisconsin, 2011) Reviewer for Hong Kong RGC Collaborative Research Fund (Hong Kong, 2010) NIH study section/site reviewer for RC3 and R43 ARRA grant applications (Washington DC, 2009) External reviewer for a faculty tenure promotion (Nanyang Technological University, Singapore, 2012) External examiner for a PhD student thesis (Nanyang Technological University, Singapore, 2011) External reviewer for a faculty tenure promotion (University of North Carolina, Charlotte, 2010) Conference Organizer: One of the symposium organizers and speakers in 2010 ACSM annual meeting (Baltimore, 2010) Section co-chair, Multimodal Biomedical Imaging V, SPIE Photonics West (San Francisco, 2010) Section co-chair, 11 th World Congress of the International Photodynamic Association (IPA, Shanghai, China, 2007)

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Guoqiang Yu, Ph.D. Associate Professor

Department of Biomedical Engineering (BME) University of Kentucky,Lexington, KY 40506-0070

Tel: 859-257-9110; Fax: 859-257-1856 Email: [email protected]

ACADEMIC POSTIONS

Department of Biomedical Engineering, University of Kentucky (UK), Lexington, KY, USA Associate Professor 2012- Assistant Professor 2007-2012

Physics & Astronomy, University of Pennsylvania, Philadelphia, PA, USA Research Assistant Professor 2006-2007 Senior Research Investigator 2004-2006 Research Associate 2002-2004 Postdoctoral Fellow 2001-2002

Physikalisch-Technische Bundesanstalt (PTB), Braunschweig, Germany Research Scientist 1999-2001

EDUCATION

Biomedical Engineering, Tianjin University, Tianjin, China Ph.D. of Biomedical Engineering -1999

AWARDS AND HONORS Editorial Board Member:

Senior editor board member for ―American Journal of Cancer Science‖ 2012-

Associate editor for ―Journal of Biomedical Optics‖ 2012-

Editorial board member of ―Open Journal of Clinical Diagnostics‖ 2012-

Editorial board member of ―International Journal of Biomedical Engineering‖ 2012-

Editorial board member of ―Spectroscopy: An International Journal‖ 2012-

Editorial board member of ―Anatomy & Physiology‖ 2011-

Editorial board member of ―Journal of Cancer Therapy‖ 2010-

Reviewer for Grant and Faculty/Student Evaluation:

Reviewer for COST-Switzerland office at the State Secretariat for Education, Research and Innovation SERI (Switzerland, 2013)

Reviewer for American Association for the Advancement of Science Research Competitiveness Program in the review of proposals submitted for funding through the King Abdulaziz City for Science and Technology (2012)

Reviewer for University of Wisconsin-Milwaukee (UWM) Research Foundation (Wisconsin, 2011)

Reviewer for Hong Kong RGC Collaborative Research Fund (Hong Kong, 2010)

NIH study section/site reviewer for RC3 and R43 ARRA grant applications (Washington DC, 2009)

External reviewer for a faculty tenure promotion (Nanyang Technological University, Singapore, 2012)

External examiner for a PhD student thesis (Nanyang Technological University, Singapore, 2011)

External reviewer for a faculty tenure promotion (University of North Carolina, Charlotte, 2010)

Conference Organizer:

One of the symposium organizers and speakers in 2010 ACSM annual meeting (Baltimore, 2010)

Section co-chair, Multimodal Biomedical Imaging V, SPIE Photonics West (San Francisco, 2010)

Section co-chair, 11th World Congress of the International Photodynamic Association (IPA, Shanghai, China, 2007)

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Awards:

Finalist for the College of Engineering Excellence in Teaching (Lutes) Award (Lexington, 2013-2014)

Notable Research Professor honored by University of Kentucky Chapter of the National Society of Black Engineers (Lexington, 2012)

Second Place Winner (out of 45+ international competitors) of Young Investigators Awards Competition in 17th Annual Meeting of the Society of Vascular Medicine and Biology (SVMB, Philadelphia, 2006)

Second Place Winner (out of 45+ international competitors) of Young Investigators Awards Competition in 15th annual meeting of the Society of Vascular Medicine and Biology (SVMB, Anaheim, 2004)

Best Poster Award (out of 80+ posters) in the Institute For Medicine AND Engineering (IME) Interdisciplinary Research Symposium 2004 (University of Pennsylvania, Philadelphia, 2004)

New Investigator Award (W81XWH-04-1-0006), Department of Defense (2004)

Media Report:

―Oxygen Debt in Patients with Fibromyalgia (FM)‖ — Dr. Yu’s research in FM was reported by Fibromyalgia Network Journal (Fall 2012, Issue 99, Page 16-17)

―Blood Monitoring Predicts Therapy Efficacy‖ — Dr. Yu was interviewed/reported by Medical Physics Web (2012-3-1)

―Biomedical Engineering Researcher’s Novel Device Could Change Breast Cancer Detection and Treatment‖ — Dr. Yu’s research was highlighted at the College of Engineering Website, University of Kentucky (2012-10-29)

Patents:

United States Letters Patent #8082015, ―Optical Measurement of Tissue Blood Flow Hemodynamics and Oxygenation‖ (2012-2032)

MANUSCRIPT REFEREE FOR JOURNALS (28) PLOS ONE, Optics Letters, Optics Express, Biomedical Optics Express, Journal of Biomedical Optics, Applied Optics, Journal of Selected Topics in Quantum Electronics, Optical Engineering, Journal of Innovative Optical Health Sciences, Journal of Modern Optics, Applied Physics Letters, Medical Physics, Journal of Electronic Imaging, IEEE Transactions on Medical Imaging, Journal of Cerebral Blood Flow and Metabolism, Biomedical Engineering Online, Biomedical Signal Processing and Control, Journal of Neoplasia, Archives of Physical Medicine and Rehabilitation, Cardiovascular & Interventional Radiology, Journal of Applied Physiology, Brain Research Bulletin, Experimental Neurology, Technology in Cancer Research and Treatment, Sensors, Journal of Visualized Experiments, Spectroscopy: An International Journal, Canadian Journal of Physiology and Pharmacology PROFESSIONAL MEMBERSHIPS (6) Optical Society of American (OSA), The International Society for Optical Engineering (SPIE), American Society of Photobiology (ASP), Society of Vascular Medicine and Biology (SVMB), American College of Sports Medicine (ACSM), Biomedical Engineering Society (BMES)

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RESEARCH RESEARCH INTERESTS Develop near-infrared diffuse optical spectroscopy and tomography for noninvasive measurements of blood flow, oxygenation and oxygen metabolism in normal and diseased tissues of animals and humans. It is expected that the functional information obtained by the diffuse optical techniques can be ultimately used for early diagnosis of various diseases and for prediction and evaluation of the efficacies of various therapies. RESEARCH FUNDING HISTORY (17) ACTIVE: Title: Diffuse Optical Monitoring of Head and Neck Tumor Therapy Sponsor: NIH R01 CA149274-01A1 07/01/2010-04/30/2015 Role: PI (Yu) Co-Is: Mahesh Kudrimoti, Scott Stevens, Brent Shelton Title: Noncontact Diffuse Optical Assessment of Pressure Ulcer and Therapy Sponsor: NIH R21 AR062356-01 02/15/2012-01/31/2015 Role: PI (Yu) Co-Is: Sara Salles, Karin Swartz Title: Noncontact Diffuse Optical Quantification of Hemodynamic Contrast in Breast Tumor Sponsor: University of Kentucky (UK) CCTS pilot program 03/01/2012-02/28/2014 Role: PI (Yu) Co-Is: Margaret Szabunio, Brent Shelton Title: Noninvasive Optical Diagnosis of Cerebrovascular Disease in Older Population Sponsor: UK Pilot Grant Funding for Studies on Alzheimer's Disease (AD)

07/01/2013-06/30/2014 Role: PI (Yu) Co-Is: Charles D. Smith, David K. Powell, Gregory A. Jicha, Yang Jiang Title: Dr. Joseph F. Pulliam Pilot Award Sponsor: University of Kentucky Markey Cancer Center 03/01/2013-02/28/2014 Role: PI (Yu) Title: Noncontact Near-infrared CCD-based 3-D Imaging of Tissue Hemodynamics and Nanoparticle

Distributions in Mouse Tumors

Sponsor: University of Kentucky Cancer Nanotechnology Training Center (CNTC) Predoctoral

Traineeship (Supported by NIH/NCI) 10/15/2013-10/14/2014 Role: Mentor (Yu) Trainee: Daniel Irwin FINISHED Title: Development of Diffuse Optical Spectroscopies for Monitoring Cerebral Blood Flow and

Oxygenation in Mouse Stroke Model Sponsor: AHA Postdoctoral Fellowship 11POST7360020 7/1/2011-6/30/2013 Role: Mentor (Yu) PI: Yu Shang Title: A Portable Optical Flow-Oximeter for Assessment of Cerebral Hemodynamics and Metabolism

during Obstructive Sleep Apnea (OSA) Sponsor: AHA BGIA 2350015 7/1/2009-6/30/2012

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Role: PI (Yu) Co-Is: Don Hayes Jr Title: Assessment of Muscle Vascular Disease with Diffuse Light Sponsor: NIH R21 HL083225-01 2/15/2006-1/31/2010 Role: PI (Yu) Co-Is: Arjun Yodh, Turgut Durduran, Thomas Floyd Title: Diffuse Optical Mapping of Blood Flow, Oxygenation, and Metabolism in Ischemic Skeletal

Muscle Sponsor: AHA BGIA #0665446U 7/1/2006-6/30/2009 Role: PI (Yu) Co-Is: Arjun Yodh, Turgut Durduran, Emile Mohler Title: Real-time Diffuse Optical Measurement for In-vivo PDT Dosimetry of Human Prostate Sponsor: DOD W81XWH-04-1-0006 2/1/2004-1/31/2007 Role: PI (Yu) Co-Is: Arjun Yodh, Turgut Durduran, Steven Hahn

Title: Contribution of Altered Muscle Hemodynamics to Fatigability in Older Persons with and without

Fibromyalgia Sponsor: NIH 5R21AG034279-01 9/15/2009-8/31/2011 Role: Co-I (Yu) PI: Charlotte Peterson, Leslie Crofford Co-Is: Guoqiang Yu, Leigh Callahan,

Title: MRI Susceptometry for Measuring Hemoglobin Saturation In Vivo Sponsor: NIH R21HL088182-01A2 4/1/2008-3/31/2010 Role: Co-I (Yu) PI: Felix Wehrli Co-Is: Guoqiang Yu, Thomas Floyd, Jeremy Magland, Emile Mohler

Title: Diffuse Light Imaging of Flow, Oxygen & Brain Metabolism Sponsor: NIH R01 HL077699-01 9/1/2004-8/31/2008 Role: Co-I (Yu) PI: Arjun G. Yodh Co-Is: Guoqiang Yu, Turgut Durduran, Joel H. Greenberg

Title: Absolute Measurement of Cerebral Blood Flow Using Diffuse Optics Sponsor: NIH R21 EB007610-01 8/1/2007-7/31/2009 Role: Co-I (Yu) PI: Turgut Durduran Co-Is: Guoqiang Yu, Arjun Yodh, Joel H. Greenberg, John A. Detre

Title: Real-time Diffuse Optical Measurement for Dosimetry During Photofrin Pleural Photodynamic

Therapy Sponsor: Upenn Abramson Cancer Center 7/1/2005-6/30/2006 Role: Co-I (Yu) PI: Steven Hahn Co-Is: Guoqiang Yu, Arjun Yodh

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PUBLICATIONS (66) Note: * indicates a student author from UK and ** indicates a student author outside UK

--2014--

1. Y. Lin, C. Huang, D. Irwin*, L. He*, Y. Shang, G. Yu, Three-dimensional flow contrast imaging of deep tissue using noncontact diffuse correlation tomography, Applied Physics Letters 104, 121103 (2014)

2. R. Cheng*, Y. Shang, S. Wang*, J. M. Evans, A. Rayapati, D. C. Randall, G. Yu, ―Near-infrared diffuse optical monitoring of cerebral blood flow and oxygenation for the prediction of vasovagal syncope‖, Journal of Biomedical Optics 19(1), 017001 (2014)

3. X. Zhang*, R. Cheng*, D. Rowe, P. Sethu, A. Daugherty, G. Yu, H. Y. Shin, ―Shear-sensitive regulation of neutrophil flow behavior and its potential impact on microvascular blood flow dysregulation in hypercholesterolemia, Arteriosclerosis, Thrombosis, and Vascular Biology 34, 587 (2014)

4. Y. Shang, L. Chen, T. Li, Y. Lin, M. Toborek, G. Yu, Precise extraction of diffuse correlation spectroscopy flow index by integration of Nth-order linear model with Monte Carlo simulation, Applied Physics Letters, Accepted (2014)

--2013--

5. T. Li, Y. Lin, Y. Shang, L. He*, C. Huang, M. Szabunio, G. Yu, ―Simultaneous measurement of deep tissue blood flow and oxygenation using noncontact diffuse correlation spectroscopy flow-oximeter‖, Scientific Reports, 3, 1358 (2013)

6. R. Cheng*, X. Zhang*, A. Daugherty, H. Shin, G. Yu, ―Noninvasive quantification of post-occlusive reactive hyperemia in mouse thigh muscle by near-infrared diffuse correlation spectroscopy‖, Applied Optics, 53(30), 7324 (2013)

7. Y. Shang, Y. Lin, B. A. Henry*, R. Cheng*, C. Huang, L. Chen, B. J. Shelton, K. R. Swartz, S. S. Salles, G. Yu, ‖Noninvasive evaluation of electrical stimulation impacts on muscle hemodynamics via integrating diffuse optical spectroscopies with muscle stimulator,‖ Journal of Biomedical Optics, 18(10), 105002 (2013)

8. L. Dong*, L. He*, Y. Lin, Y. Shang, G. Yu, ―Simultaneously extracting multiple parameters via fitting one single autocorrelation function curve in diffuse correlation spectroscopy‖, IEEE Transactions on Biomedical Engineering, 60(2), 361 (2013)

9. R. Srikuea, T. B. Symons, D. E. Long, J. Lee, Y. Shang, P. J. Chomentowski, G. Yu, L. J. Crofford, C. A. Peterson, ―Analysis of physical function and skeletal muscle properties in post-menopausal women with fibromyalgia‖, Arthritis & Rheumatism, 65(2), 519 (2013)

10. L. He*, Y. Lin, Y. Shang, B. Shelton, G. Yu, ―Using optical fibers with different modes to improve the signal-to-noise ratio (SNR) of diffuse correlation spectroscopy (DCS) flow-oximeter measurements‖, Journal of Biomedical Optics 18(3), 037001 (2013)

11. R. C. Mesquita, M. Putt, M. Chandra, G. Yu, X. Xing, S. W. Han, G. Lech, Y. Shang, T. Durduran, C. Zhou, A. G. Yodh, E. R. Mohler, III, ―Diffuse optical characterization of an exercising patient group with peripheral artery disease,‖ Journal of Biomedical Optics, 18(5), 057007 (2013)

12. Y. Shang, K. Gurley*, G. Yu, ―Diffuse Correlation Spectroscopy (DCS) for Assessment of Tissue Blood Flow in Skeletal Muscle: Recent Progress,‖ Anatomy & Physiology, 3(2), 1000128, Invited Review (2013)

13. G. Yu, R. Cheng*, J. Yang, Z. Yang, M. Xun, T. Liu, Y. Li, ―Near-infrared diffuse correlation spectroscopy (DCS) for noninvasive monitoring of photodynamic therapy (PDT)‖, International Journal of Biomedical Engineering, 36(3), 134-138, Invited Review (2013)

--2012--

14. Y. Shang, K. Gurley*, B. Symons, D. Long, R. Srikuea, L. J. Crofford, C. A. Peterson, G. Yu, ―Noninvasive optical characterization of muscle blood flow, oxygenation, and metabolism in women with fibromyalgia‖, Arthritis Research & Therapy, 14(6), R236 (2012)

15. K. Gurley*, Y. Shang, G. Yu, ―Noninvasive optical quantification of absolute blood flow, blood oxygenation, and oxygen consumption rate in exercising skeletal muscle,‖ Journal of Biomedical Optics 17, 075010 (2012)

16. R. Cheng*, Y. Shang, D. Hayes, S. Saha, G. Yu, ―Noninvasive optical evaluation of spontaneous low frequency oscillations in cerebral hemodynamics,‖ NeuroImage 62(3), 1445-1454 (2012)

17. L. Dong*, M. Kudrimoti, R. Cheng*, Y. Shang, E. L. Johnson, S. D. Stevens, B. J. Shelton, G. Yu, ―Noninvasive diffuse optical monitoring of head and neck tumor

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blood flow and oxygenation during radiation delivery,‖ Biomedical Optics Express 3, 259-272 (2012) (highlighted as spotlight paper)

18. Y. Lin, L. He*, Y. Shang, G. Yu, ―Noncontact diffuse correlation spectroscopy for noninvasive deep tissue blood flow measurement,‖ Journal of Biomedical Optics Letters 17(2), 010502 (2012)

19. N. Munk, B. Symons, Y. Shang, R. Cheng*, G. Yu, ―Noninvasively measuring the hemodynamic effects of massage on skeletal muscle: a novel hybrid near-Infrared diffuse optical instrument,‖ Journal of Bodywork & Movement Therapies 16(1), 22-28 (2012)

20. G. Yu, T. Durduran, C. Zhou, R. Cheng*, A. G. Yodh, ―Near-infrared diffuse correlation spectroscopy (DCS) for assessment of tissue blood flow,‖ Chapter 10, Handbook of Biomedical Optics, D.A. Boas, C. Pitris, and N. Ramanujam Editors, Taylor & Francis Books Inc, page:195-216 (2011)

21. G. Yu, ―Near-infrared diffuse correlation spectroscopy (DCS) in cancer diagnosis and therapy monitoring,‖ Journal of Biomedical Optics 17(2), 010901, Invited Review (2012)

22. G. Yu, ―Diffuse correlation spectroscopy (DCS): a diagnostic tool for assessing tissue blood flow in vascular-related diseases and therapies,‖ Current Medical Imaging Reviews 8(3), 194-210, Invited Review (2012)

23. G. Yu, "Near-infrared diffuse correlation spectroscopy (DCS) for assessing deep tissue blood flow", Anatomy and Physiology 2(2) 1000e115, Invited Editorial Review (2012)

24. L. Chen, Y. Shang, E. Sipos, K. E. Saatman, G. Yu, M Toborek, ―Novel experimental model for repeated forebrain ischemia-reperfusion,‖ Journal of experimental stroke and translational medicine, Vol. 5, No. 1, pp. 1-10 (2012)

25. A. L. Maas**, S. L. Carter, E. P. Wileyto**, J. Miller**, M. Yuan, G. Yu, A. Durham, T. M. Busch, ―The tumor vascular microenvironment determines responsiveness to photodynamic therapy,‖ Cancer Research 72(8): 2079-88 (2012)

--2011--

26. Y. Shang, L. Chen, M Toborek, G. Yu, ―Diffuse optical monitoring of repeated cerebral ischemia in mice,‖ Optics Express 19, 20301-20315 (2011) (highlighted by Virtual Journal for Biomedical Optics)

27. D. Irwin*, L. Dong*, Y. Shang, R. Cheng*, M. Kudrimoti, S. D. Stevens, G. Yu, "Influences of tissue absorption and scattering on diffuse correlation spectroscopy blood flow measurements," Biomedical Optics Express 2, 1969–1985 (2011)

28. Y. Shang, R. Cheng*, L. Dong*, S. J. Ryan, S. P. Saha, G. Yu, ―Cerebral monitoring during carotid endarterectomy using near-infrared diffuse optical spectroscopies and electroencephalogram,‖ Physics in Medicine and Biology 56, 3015–3032 (2011)

29. G. Yu, Y. Shang, Y. Zhao, R. Cheng*, L. Dong*, S. P. Saha, ―Intraoperative Evaluation of Revascularization Effect on Ischemic Muscle Hemodynamics Using Near-infrared Diffuse Optical Spectroscopies,‖ Journal of Biomedical Optics 16(2), 027004 (2011) (highlighted by Virtual Journal of Biological Physics Research)

30. R. C. Mesquita, T. Durduran, G. Yu, E. M. Buckley**, M. N. Kim**, C. Zhou, R. Choe, U. Sunar, A. G. Yodh, “Direct measurement of tissue blood flow & metabolism with diffuse optics," Phil. Trans. R. Soc. A 369, 4390–4406, doi:10.1098/rsta.2011.0232 (2011)

--2010--

31. Y. Shang, T. B. Symons, T. Durduran, A. G. Yodh, G. Yu, "Effects of muscle fiber motion on diffuse correlation spectroscopy blood flow measurements during exercise," Biomedical Optics Express 1, 500-511 (2010)

32. T. M. Busch, H. W. Wang, E. P Wileyto**, G. Yu, R. M. Bunte, ―Increasing damage to tumor blood vessels during vascular-targeting PDT through use of low fluence rate,‖ Radiation Research 0033-7587/10 (2010)

33. T. Durduran, C. Zhou, E. M. Buckley**, M. N. Kim**, G. Yu, R. Choe, W. J. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, D. J. Licht. ―Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,‖ Journal of Biomedical Optics 15(3):037004 (2010)

34. M. N. Kim**, T. Durduran, S. Frangos**, B. L. Edlow**, E. M. Buckley**, H. E. Moss**, C. Zhou, G. Yu, R. Choe**, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, W. A. Kofke, "Noninvasive measurement of cerebral blood flow and blood oxygenation using

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near-infrared diffuse correlation spectroscopies in critically brain-injured adults," Neurocrit Care 12(2): 173-180 (2010)

--2009--

35. Y. Shang, Y. Zhao, R. Cheng*, L. Dong*, D. Irwin*, G. Yu, ―Portable optical tissue flow oximeter based on diffuse correlation spectroscopy,‖ Optics Letters 34(22), 3556-3558 (2009) (highlighted by Virtual Journal of Biological Physics Research)

36. T. M. Busch, X. Xing**, G. Yu, A. G. Yodh, E. P. Wileyto**, H. W. Wang, T. Durduran, T. C. Zhu, K. K.H. Wang, ―Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to photofrin photodynamic therapy,‖ Photochemistry & Photobiology Science 8: 1683-1693 (2009)

37. C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston**, S. H. Friess**, R. N. Ichord**, S. S. Margulies, and A. G. Yodh, ―Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,‖ Journal of Biomedical Optics 14(3):034015 (2009)

38. T. Durduran, C. Zhou, L. E. Brian**, G. Yu, R. Choe, M. N. Kim**, B. L. Cucchiara**, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, J. A. Detre, "Transcranial optical monitoring of cerebral blood flow and hemoglobin concentration in acute stroke patients during positional interventions," Annals of Neurology, Optics Express 17(5):3884-3902 (2009)

39. M. Buckley**, N. M. Cook**, T. Durduran, M. N. Kim**, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, A. G. Yodh. ―Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial doppler ultrasound,‖ Optics Express, 17(15):12571-12581 (2009)

--2008--

40. C. Zhou**, T. Shimazu**, T. Durduran, J. Luckl**, D. Y. Kimberg**, G. Yu, X. H. Chen**, J. A. Detre, A. G. Yodh, J. H. Greenberg, "Acute functional recovery of cerebral blood flow after forebrain ischemia in rat," Journal of Cerebral Blood Flow & Metabolism 28(7), 1275-1284 (2008)

--2007--

41. G. Yu, T. F. Floyd, T. Durduran, C. Zhou**, J. A. Detre, A. G. Yodh, ―Diffuse Correlation Spectroscopy for Muscle Blood Flow: Validation with Arterial-Spin-Labeling Perfusion MRI,‖ Optics Express, 15:1064-1075, 2007

42. U. Sunar**, S. Makonnen**, C. Zhou**, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, A. G. Yodh, "Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies," Optics Express 15(23), 15507-15516 (2007)

43. C. Zhou**, R. Choe, N. Shah**, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, A. G. Yodh, "Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy," Journal of Biomedical Optics 12(5), 051903 (2007)

--2006--

44. C. Zhou**, G. Yu, D. Furuya, J. A. Detre, J. H. Greenberg, A. G. Yodh, T. Durduran, "Diffuse optical correlation tomography of cerebral blood flow during cortical spreading depression in rat brain," Optics Express 24(3), 1125-1144 (2006)

45. G. Yu, T. Durduran, C. Zhou**, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, A. G. Yodh, "Real-time in situ monitoring of human prostate photodynamic therapy with diffuse light," Photochemistry & Photobiology 82(5), 1279-1284 (2006)

46. U. Sunar**, H. Quon, T. Durduran**, J. Zhang**, J. Du**, C. Zhou**, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, A. G. Yodh, "Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study," Journal of Biomedical Optics 11(6), 064021 (2006)

47. K. L. Du**, R. Mick**, T. M. Busch, T. C. Zhu, J. C. Finlay, G. Yu, A. G. Yodh, S. B. Malkowicz, D. Smith, R. Whittington, D. Stripp, S. M. Hahn, "Preliminary results of interstitial motexafin lutetium-mediated PDT for prostate cancer," Lasers in Surgery and Medicine 38(5), 427-434 (2006)

--2005--

48. G. Yu, T. Durduran, C. Zhou**, H. W. Wang, M. E. Putt, H. M. Saunders, C. M. Sehgal, E. Glatstein, A. G. Yodh, T. M. Busch, "Noninvasive monitoring of murine tumor blood flow during and after

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photodynamic therapy provides early assessment of therapeutic efficacy," Clinical Cancer Research 11(9), 3543-3552 (2005)

49. G. Yu, T. Durduran**, G. Lech, C. Zhou**, B. Chance, E. R. Mohler, 3rd, A. G. Yodh, "Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies," Journal of Biomedical Optics 10(2), 024027 (2005)

50. T. Durduran**, R. Choe**, G. Yu, C. Zhou**, J. C. Tchou, B. J. Czerniecki, A. G. Yodh, "Diffuse optical measurement of blood flow in breast tumors," Optics Letters 30(21), 2915-2917 (2005)

--2004--

51. T. Durduran**, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou**, A. G. Yodh, "Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation," Optics Letters 29(15), 1766-1768 (2004)

52. T. Durduran**, M. G. Burnett, G. Yu, C. Zhou**, D. Furuya, A. G. Yodh, J. A. Detre, J. H. Greenberg, "Spatiotemporal quantification of cerebral blood flow during functional activation in rat somatosensory cortex using laser-speckle flowmetry," Journal of Cerebral Blood Flow & Metabolism 24(5), 518-525 (2004)

--2003--

53. G. Yu, T. Durduran**, D. Furuya, J. H. Greenberg, A. G. Yodh, "Frequency-domain multiplexing system for in vivo diffuse light measurements of rapid cerebral hemodynamics," Applied Optics 42(16), 2931-2939 (2003)

54. R. Choe**, T. Durduran**, G. Yu, M. J. Nijland**, B. Chance, A. G. Yodh, N. Ramanujam, "Transabdominal near infrared oximetry of hypoxic stress in fetal sheep brain in utero," Proc Natl Acad Sci (PNAS) USA 100(22), 12950-12954 (2003)

--1998 to 2002--

55. K. Hasche, K. Herrmann, W. Mirande, R. Deemann, L. Vitushkin, M. Xu, G. Yu, "Calibrated scanning force microscope with capabilities in the subnanometre range," Surface and Interface Analysis 33(2), 71-74 (2002)

56. G. Yu, Y. Li, Q. Y, X. Hu, "Dynamics models in sclerostomy with iridotomy," Chinese Journal of Biomedical Engineering 21(3), 275-281 (2002)

57. Q. Yu, G. Yu, X. Hu, "Optimization of pulsed CO2 laser sclerostomy," Journal of Tianjin University (Science and Technology) 34(2), 193-197 (2001)

58. G. Yu, A. Liu**, G. Zhang**, X. Hu, "Thermal physical property measurement using plane-heat source with constant heat rate," Journal of Apparatus and Instruments 21(1), 113-115 (2000)

59. G. Yu, A. Liu**, X. Hu, "Scanning tunneling microscopy (STM) system with atomic micropositioning " Aviation Precision Manufacturing Technology 35(1), 35-37 (1999)

60. G. Yu, X. Hu, A. Liu**, "Nanometer scale positioning control and nanofabrication," Journal of Tianjin University (Science and Technology) 32(3), 308-311 (1999)

61. A. Liu**, G. Yu, Y. Yang**, X. Hu, "Image reconstruction for scanning tunneling microscopy (STM)," Journal of Chinese Electron Microscopy Society 18(1), 115-118 (1999)

62. D. Li**, G. Yu, "Multi-channel real-time monitoring system of environmental protecting equipments," Monitoring Technique 18(2), 19-22 (1999)

63. X. Hu, G. Yu, A. Liu**, Y. Yang**, "3D monolithic ultra-micropositioning system," Journal of Chinese Electron Microscopy Society 18(1), 141-144 (1999)

64. G. Yu, A. Liu**, G. Zhang, X. Hu, "Thermal physical property measurement using hot-line source with constant heat rate," Aviation Precision Manufacturing Technology 34(6), 39-41 (1998)

65. G. Yu, D. Li**, "Real-time monitoring of environmental protecting equipments," Electronics and Automation 27(4), 8-11 (1998)

66. A. Liu**, G. Yu, P. Qi**, X. Hu, "Positioning errors of the scanning probe microscopy (SPM) scanner," Aviation Precision Manufacturing Technology 34(4), 33-35 (1998)

9

PRESENTATIONS/PROCEDINGS IN CONFERENCES/SEMINARS Invited Talks (29) 1. Characterizing breast tumors using optical imaging, UK Symposia on Advanced Medical Imaging,

(Lexington, KY, April 2014) 2. 3-D flow contrast imaging of breast tumor using non-contact diffuse correlation tomography, UK Annual

Breast Cancer Symposium (Lexington, KY, March 2014) 3. Non-contact 3-D imaging of blood flow, blood oxygenation and drug concentration in deep tumors using

near-infrared diffuse light, UK Markey Research Seminar (Lexington, KY, June 2013) 4. Non-contact 3-D imaging of blood flow, blood oxygenation and oxidative metabolism in breast tumor

using near-infrared diffuse light, UK Breast Translational Group meeting (Lexington, KY, May 2013) 5. Non-contact 3-D imaging of blood flow, blood oxygenation and drug concentration in deep tumors using

near-infrared diffuse light, UK CCTS Spring Conference (Lexington, KY, April 2013) 6. ―Near-infrared diffuse optical measurement of blood flow, blood oxygenation and oxygen metabolism in

deep tissues‖, Institute of Biomedical Engineering, Chinese Academy of Medical Science, (Tianjin, China, Sep. 2012)

7. Near-infrared Diffuse Optical Spectroscopies for Measurement of Deep Tissue Blood Flow, Oxygenation and Metabolism, IEEE Biomedical Instrumentation for the Future of Instrumentation International Workshop (FIIW), Oak Ridge National Laboratory (Oak Ridge, TN, Nov. 2011)

8. Near-Infrared Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation and Metabolism, Center for Computational Science seminar, University of Kentucky (Lexington, KY, Jan. 2011)

9. Near-Infrared Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation and Metabolism, Kentucky NSF EPSCoR seminar, University of Louisville (Louisville, KY, Nov. 2010)

10. How to Use Near-infrared Spectroscopies to Evaluate Skeletal Muscle, UK Muscle Forum, University of Kentucky (Lexington, KY, Sep. 2010)

11. Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism in Skeletal Muscle, UK Lung Biology Research Group Meeting, University of Kentucky (Lexington, KY, Feb. 2008)

12. Near-Infrared Diffuse Optical Technologies for Cancer Research, UK HOBMT Grand Rounds, Markey Cancer Center, University of Kentucky (Lexington, KY, March 2008)

13. Diffuse Optical Quantification of Tissue Blood Flow, Oxygenation and Metabolism in Brain and Muscle, UK Neurology Grand Rounds, University of Kentucky (Lexington, KY, March 2008)

14. Diffuse Optical Quantification of Tissue Blood Flow, Oxygenation and Metabolism in Brain and Muscle, UK Pediatrics Research Group Meeting, University of Kentucky (Lexington, KY, Apr. 2008)

15. Diffuse Optical Spectroscopy and Tomography of Tissue Hemodynamics, UK Symposia on Advanced Medical Imaging, University of Kentucky (Lexington, KY, June 2008)

16. Near-infrared Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation and Metabolism, UK Clinical and Translational course (BSC772), CTS Fall Seminar Serial Grand Rounds, University of Kentucky (Lexington, KY, Aug. 2008).

17. Diffuse Optical Measurements of Prostate Blood Flow and Oxygenation During Interstitial Photodynamic Therapy, in the inaugural IMPaCT (Innovative Minds in Prostate Cancer Today) meeting (Atlanta, GA, Sep. 2007)

18. Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism, in the Department of Biomedical Engineering, University of Georgia (Athens, GA, Sep. 2007)

19. Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism, in the Department of Biomedical Engineering, Stony Brook University (Long Island, NY, May, 2007)

20. Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism, in the Center for Biomedical Engineering, University of Kentucky (Lexington, KA May 2007)

21. Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism, in the Department of Biomedical Engineering, Wayne State University (Detroit, MI, Sep. 2006)

22. Concurrent Optical-MRI Measurement of Limb Blood Flow/Perfusion, in SVMB 17th Annual Meeting (Philadelphia, PA, June 2006)

23. Diffuse Optical Measurements of Tissue Blood Flow and Oxygenation During Photodynamic Therapy, in Wellman Center for Photomedicine, MGH, Harvard Medical School (Boston, MA, May 2006)

24. Assessment of Muscle Vascular Disease with Diffuse Light, in Molecular Beacons – Novel Optical and NMR Approaches to Cancer Study: Detection and Therapy of Cancer (BMB Course #18), (Philadelphia, PA, Nov. 2005)

10

25. Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscles Measured by Noninvasive Near-infrared Diffuse Optical Spectroscopies, in Vascular Surgery Conference, Division of Vascular Surgery, Department of Surgery, University of Pennsylvania (Philadelphia, PA, Nov. 2004)Near-Infrared Diffuse Optical Spectroscopies and Arterial-Spin-Labeling MRI of Human Muscle -- Validation and Correlation of Two Complementary and Noninvasive Techniques, in Center for Advanced Magnetic resonance Imaging and Spectroscopy (CAMRIS), Hospital of University of Pennsylvania (Philadelphia, PA, Oct. 2004)

27. Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, in PDT Seminar, Hospital of University of Pennsylvania (Philadelphia, PA, Sep. 2004)

28. Noninvasive Quantification of Oxidative Metabolism in Human Skeletal Muscle Using Hybrid Near-infrared Diffuse Optical Spectroscopies, in SVMB 15th Annual Meeting (Anaheim, CA, June 2004)

29. Noninvasive Quantification of Oxidative Metabolism in Human Skeletal Muscle Using Hybrid Near-infrared Diffuse Optical Spectroscopies, in Britton Chance Lab Seminar, University of Pennsylvania (Philadelphia, PA, May 2004)

Presentations/Abstracts in Conferences/Seminars (208) Note: * indicates a student author from UK and ** indicates a student author outside UK

--2014--

1. G. Yu, Y. Shang, R. Cheng*, J. M. Evans, A. Rayapati, D. C. Randall, ―Diffuse optical monitoring of cerebral blood flow and oxygenation for the prediction of vasovagal syncope‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

2. D. Irwin*, Y. Lin, C. Huang, L. He*, Y. Shang, M. Xu, H. Wang, J. Luo, G. Yu, ―Noncontact near-infrared 3-D blood flow contrast imaging on small animal mammary tumors: a case study‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

3. L. He*, Y. Lin, C. Huang, D. Irwin*, S. M. Margaret, G. Yu, ―3-D blood flow imaging of breast tumor using noncontact diffuse correlation tomography: computer simulations‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

4. Y. Shang, Y. Lin, B. A. Henry*, R. Cheng*, C. Huang, K. R. Swartz, S. S. Salles, G. Yu, ―Electrical stimulation effects on muscle hemodynamics measured by diffuse correlation spectroscopy flow-oximeter‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

5. Y. Shang, T. Li, Y. Lin, G. Yu, ―Precisely extracting diffuse correlation spectroscopy blood flow index by integrating Nth-order linear model with Monte Carlo simulation‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

6. Y. Lin, T. Li, Y. Shang, L. He*, C. Huang, M. Szabunio, G. Yu, ―Simultaneous measurements of deep tissue blood flow and oxygenation using noncontact diffuse correlation spectroscopy flow-oximeter‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

7. Y. Lin, C. Huang, D. Irwin*, L. He*, Y. Shang, G. Yu, ―Noncontact three-dimensional flow contrast imaging of deep tissue using diffuse correlation tomography‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014 (Oral)

8. M. Zhao*, Y. Shang, B. Henry*, T. L. Uhl, G. Yu, ―Tissue metabolic rate of oxygen consumption in calf muscle measured by arterial and venous occlusion protocols‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

9. C. Huang, Y. Lin, L. He*, D. Irwin*, G. Yu, ―A computer-aided-design approach to align sources and detectors on arbitrary tissue surface for noncontact diffuse correlation tomography‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

10. L. Dong*, L. He*, Y. Lin, Y. Shang, G. Yu, ―Simultaneously fitting multiple parameters from one single autocorrelation function in diffuse correlation spectroscopy‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2014

--2013--

11. R. Cheng*, X. Zhang*, H. Shin, G. Yu, ―Noninvasive quantification of skeletal muscle microvasculature blood flow in mouse thigh by diffuse correlation spectroscopy‖, 60th Annual Meeting of American College of Sports and Medicine (ACSM), Indianapolis, Indiana, 2013

12. B. A. Henry*, Y. Shang, K. Gurley*, G. Yu, Diffuse correlation spectroscopy probe design for obtaining stable blood flow measurement in skeletal muscle‖, 60th Annual Meeting of American College of Sports and Medicine (ACSM), Indianapolis, Indiana, 2013

11

13. Y. Shang, Y. Lin, B. A. Henry*, R. Cheng*, Chong Huang, K. R Swartz, S. S. Salles, G. Yu, Noninvasive diffuse optical detection of muscle hemodynamic improvements by electrical stimulation‖, 60th Annual Meeting of American College of Sports and Medicine (ACSM), Indianapolis, Indiana, 2013

14. G. Yu, Y. Shang, K. Gurley*, B. Symons, D. Long, R. Srikuea, L. J. Crofford, C. A. Peterson, ―Noninvasive optical characterization of muscle blood flow, oxygenation, and metabolism in women with fibromyalgia‖, 60th Annual Meeting of American College of Sports and Medicine (ACSM), Indianapolis, Indiana, 2013

15. M. R. Kudrimoti, L. Dong*, G. Treharne, L. Johnson, S. D. Stevens, B. J. Shelton, G. Yu, ―Instantaneous hemodynamic changes noted during radiation therapy delivery in real time in head/neck squamous cancers‖, ASTRO 55th Annual Meeting, Atlanta, 2013

16. X. Zhang, R. Cheng*, D. Rowe, P. Sethu, G. Yu, A. Daugherty, H. Y. Shin, ―The contributory role of impaired neutrophil fluid shear mechanotransduction in hypercholesterolemia-related dysregulation of microvascular blood flow‖, BMES 2013 Annual Scientific Meeting, Seattle, WA, 2013 (Oral)

17. B. A. Henry*, Y. Shang, M. Zhao*, T. Uhl, and G. Yu, ―Diffuse optical spectroscopies for continuous monitoring of absolute tissue hemodynamics in calf muscle during plantar flexion exercise‖, University of Kentucky Muscle Biology Fall Retreat, Lexington, KY, 2013

18. M. Zhao*, Y. Shang, B. A. Henry*, G. Yu, ―Measurements of tissue metabolic rate of oxygen consumption in skeletal muscle using arterial and venous occlusion protocols‖, University of Kentucky Muscle Biology Fall Retreat, Lexington, KY, 2013

19. Y. Shang, Y. Lin, B. A. Henry*, R. Cheng*, C. Huang, L. Chen, B. J. Shelton, K. R. Swartz, S. S. Salles, G. Yu, ―Integration of diffuse optical spectroscopies with muscular stimulator for noninvasive evaluation of electrical stimulation impacts on muscle hemodynamics‖, Gill Heart Cardiovascular Research Day, Poster Section, University of Kentucky, Lexington, KY, 2013

20. M. Zhao*, Y. Shang, B. A. Henry*, G. Yu, ―Measurements of tissue metabolic rate of oxygen consumption in skeletal muscle using arterial and venous occlusion protocols‖, University of Kentucky Muscle Biology Fall Retreat, Lexington, KY, 2013

21. C. Huang, A. Bahrani*, W. Kong*, Y. Lin, G. Yu, ―Noninvasive evaluation of cardiovascular function by a finger blood flow sensor‖, University of Kentucky Muscle Biology Fall Retreat, Lexington, KY, 2013

22. Y. Shang, Y. Lin, B. A. Henry*, R. Cheng*, C. Huang, L. Chen, B. J. Shelton, K. R. Swartz, S. S. Salles, G. Yu, ―Integration of diffuse optical spectroscopies with muscular stimulator for noninvasive evaluation of electrical stimulation impacts on muscle hemodynamics‖, Gill Heart Cardiovascular Research Day, Poster Section, University of Kentucky, Lexington, KY, 2013

23. C. Huang, A. Bahrani*, W. Kong*, Y. Lin, G. Yu, ―Noninvasive evaluation of cardiovascular function by a finger blood flow sensor‖, Gill Heart Cardiovascular Research Day, Poster Section, University of Kentucky, Lexington, KY, 2013

24. Y. Hou, Y. Shang, R. Cheng*, Y. Zhao, Y. Qin, D. Hayes, Jr., G. Yu, ―Overnight monitoring of cerebral hemodynamic variations during obstructive sleep apnea-hypopnea‖, Gill Heart Cardiovascular Research Day, Poster Section, University of Kentucky, Lexington, KY, 2013

25. Y. Shang, R. Cheng*, S. Wang, J. Evans, A. Rayapati, D. C. Randall, and G. Yu, ―Prediction of vasovagal syncope by monitoring of cerebral blood flow and oxygenation with diffuse light‖, Gill Heart Cardiovascular Research Day, Poster Section, University of Kentucky, Lexington, KY, 2013

26. Y. Shang, R. Cheng*, D. Hayes, Jr., S. P. Saha, G. Yu, ―Noninvasive evaluation of spontaneous low frequency oscillations in cerebral blood flow and oxygenation with diffuse optics‖, Gill Heart Cardiovascular Research Day, Poster Section, University of Kentucky, Lexington, KY, 2013

27. R. Cheng*, Y Shang, S. Wang*, J. Evans, A. Rayapati, D. C. Randall, G. Yu, ―Near-infrared diffuse optical monitoring of cerebral blood flow and oxygenation for the prediction of vasovagal syncope‖, UK CCTS Spring Conference, Lexington, KY, 2013 (Oral)

28. X. Zhang, R. Cheng*, A. Daugherty, G. Yu, H. Y. Shin, ―Rheological Impact of Dysregulated Neutrophil Shear Stress Mechanotransduction on Hypercholesterolemia-Related Microvascular Pathophysiology‖, UK CCTS Spring Conference, Lexington, KY, 2013 (Oral)

29. X. Luan, Y Shang, C. Huang, Yanli Qin, G. Yu, ―Gingival blood flow measurements using near-infrared diffuse correlation spectroscopy‖, UK CCTS Spring Conference, Lexington, KY, 2013 (Oral)

30. Y. Qin, X Luan, Y. Shang, C. Huang, Yajun Hou, G. Yu, ―A near-infrared broadband spectroscopy for tissue blood oxygenation measurement‖, UK CCTS Spring Conference, Lexington, KY, 2013

31. Y. Hou, Y. Shang, R. Cheng*, Y. Qin, D. Hayes, G. Yu, ―Diffuse Optical Monitoring of Cerebral Hemodynamics During Sleep Apnea‖, UK CCTS Spring Conference, Lexington, KY, 2013

12

32. D. Irwin*, Y. Lin, L. He*, C. Huang*, Y. Shang*, M. Zhao*, G. Yu, ―Noncontact 3-D imaging of small animal tumors with combined diffuse optical, correlation, and fluorescence tomography: preliminary results in phantoms‖, UK CCTS Spring Conference, Lexington, KY, 2013

33. L. He*, Y. Lin, C. Huang, D. Irwin*, M. Szabunio, G. Yu, Noncontact diffuse optical 3-D imaging of hemodynamic contrasts in breast tumor: computer simulation‖, UK CCTS Spring Conference, Lexington, KY, 2013

34. C. Huang, Y. Lin, L. He*, Y. Shang, D. Irwin*, M. Szabunio, G. Yu, ―Noncontact diffuse optical 3-D imaging of hemodynamic contrasts in breast tumor: geometrical reconstruction and alignment of optical sources and detectors, UK CCTS Spring Conference, Lexington, KY, 2013

35. Yu Shang, Yu Lin, B. Henry*, R. Cheng*, C. Huang, K. R. Swartz, S. S. Salles, G. Yu, ―Integration of diffuse optical spectroscopies with muscular stimulator for noninvasive evaluation of electrical stimulation impacts on muscle hemodynamics, UK CCTS Spring Conference, Lexington, KY, 2013

36. L. Dong*, M. Kudrimoti, Y. Lin, C. Huang, Y. Shang, S. D. Stevens, B.J. Shelton, G. Yu, ―Noninvasive diffuse optical monitoring of hemodynamic chances in head and neck tumors throughout radiation therapy‖, UK CCTS Spring Conference, Lexington, KY, 2013

37. M. Zhao*, Y. Shang, B. A. Henry*, G. Yu, ―Comparison of ultrasound imaging and skinfold caliper measurements of subcutaneous adipose tissue thickness‖, UK CCTS Spring Conference, Lexington, KY, 2013

38. Y. Lin, T. Li, Y. Shang, L. He*, C. Huang*, M. Szabunio, G. Yu, ―Simultaneous measurement of deep tissue blood flow and oxygenation using noncontact diffuse correlation spectroscopy flow-oximeter‖, UK CCTS Spring Conference, Lexington, KY, 2013

39. R. Cheng*, Y. Shang, D. Hayes, S. P. Saha, G. Yu, ―Noninvasive optical evaluation of spontaneous low frequency oscillations in cerebral blood flow and oxygenation‖, OSU CCTS Spring Conference, Columbus, OH, 2013

40. R. Cheng*, Y Shang, S. Wang*, J. Evans, A. Rayapati, D. C. Randall, G. Yu, ―Near-infrared diffuse optical monitoring of cerebral blood flow and oxygenation for the prediction of vasovagal syncope‖, OSU CCTS Spring Conference, Columbus, OH, 2013

41. D. Irwin*, Y. Lin, L. He*, C. Huang*, Y. Shang*, M. Zhao*, G. Yu, ―Noncontact 3-D imaging of small animal tumors with combined diffuse optical, correlation, and fluorescence tomography: preliminary results in phantoms‖, UK Markey Cancer Research Day, Lexington, KY, 2013

42. L. He*, Y. Lin, C. Huang, D. Irwin*, M. Szabunio, G. Yu, Noncontact diffuse optical 3-D imaging of hemodynamic contrasts in breast tumor: computer simulation‖, UK Markey Cancer Research Day, Lexington, KY, 2013

43. C. Huang, Y. Lin, L. He*, Y. Shang, D. Irwin*, M. Szabunio, G. Yu, ―Noncontact diffuse optical 3-D imaging of hemodynamic contrasts in breast tumor: geometrical reconstruction and alignment of optical sources and detectors, UK Markey Cancer Research Day, Lexington, KY, 2013

44. L. Dong*, M. Kudrimoti, Y. Lin, C. Huang, Y. Shang, S. D. Stevens, B.J. Shelton, G. Yu, ―Noninvasive diffuse optical monitoring of hemodynamic chances in head and neck tumors throughout radiation therapy‖, UK Markey Cancer Research Day, Lexington, KY, 2013

45. Y. Lin, T. Li, Y. Shang, L. He*, C. Huang*, M. Szabunio, G. Yu, ―Simultaneous measurement of deep tissue blood flow and oxygenation using noncontact diffuse correlation spectroscopy flow-oximeter‖, UK Markey Cancer Research Day, Lexington, KY, 2013

--2012–

46. R. Cheng*, Y. Shang, G. Yu, ―Noninvasive optical evaluation of cerebral autoregulation in patients with obstructive sleep apnea‖, Markesbery Symposium on Aging and Dementia, Lexington, KY, 2012

47. R. Cheng*, Y. Shang, S. Saha, G. Yu, ―Noninvasive optical evaluation of spontaneous low frequency oscillations in cerebral blood flow and oxygenation‖, Markesbery Symposium on Aging and Dementia, Lexington, KY, 2012

48. Y. Shang, R. Cheng*, L. Dong*, S. Ryan, S. Saha, G. Yu, ―Cerebral monitoring during carotid endarterectomy using near-infrared diffuse optical spectroscopies and electroencephalogram‖, Markesbery Symposium on Aging and Dementia, Lexington, KY, 2012

49. R. Cheng*, X. Zhang*, H. Shin, G. Yu, ―Noninvasive quantification of skeletal muscle microvasculature blood flow in mouse thigh by diffuse correlation spectroscopy‖, UK Muscle Biology Fall Retreat, Lexington, KY, 2012

13

50. Y. Shang, K. Gurley*, B. Symons, D. Long, R. Srikuea, L. J. Crofford, C. A. Peterson, G. Yu, ―Noninvasive optical quantification of muscle blood flow, blood oxygenation, and metabolism in women with fibromyalgia‖, UK Muscle Biology Fall Retreat, Lexington, KY, 2012

51. K. Gurley*, Y. Shang, G. Yu, ―Use of hybrid diffuse optical spectroscopies in continuous monitoring of blood flow, blood oxygenation, and oxygen consumption rate in exercising skeletal muscle‖, UK Muscle Biology Fall Retreat, Lexington, KY, 2012

52. S. P. Saha, Y. Shang, R. Cheng*, L. Dong*, S. J. Ryan, G. Yu, ―Diffuse correlation spectroscopy for cerebral monitoring during carotid endarterectomy: a novel technique‖, Annual Meeting of the International College of Surgeons Atlanta, GA, 2012 (Oral)

53. R. Cheng*, Y. Shang, D. Hayes, S. P. Saha, G. Yu, ―Noninvasive optical evaluation of spontaneous low frequency oscillations in cerebral blood flow and oxygenation‖, UK CCTS Spring Conference, Lexington, KY, 2012 (Oral)

54. K. Gurley*, Y. Shang, G. Yu, ―Noninvasive optical quantification of absolute blood flow and oxygen consumption rate in exercising skeletal muscle‖, 59th Annual Meeting of American College of Sports and Medicine (ACSM), San Francisco, CA, 2012

55. Y. Shang, R. Cheng*, L. Dong*, S. J. Ryan, S. P. Saha, G. Yu, ―Comparison of diffuse optical spectroscopies and electroencephalogram for cerebral monitoring during carotid endarterectomy‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012

56. Y. Shang, K. Gurley*, B. Symons, D. Long, J. Lee, R. Srikuea, L. Crofford, C. Peterson, G. Yu, ―Diffuse optical detecting hemodynamic responses during fatiguing exercise in women with fibromyalgia‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012

57. K. Gurley*, Y. Shang, G. Yu, ―Noninvasive optical quantification of absolute blood flow and oxygen consumption rate in exercising skeletal muscle‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012

58. Y. Lin, L. He*, Y. Shang, G. Yu, ―Noncontact diffuse correlation spectroscopy probe for deep tissue blood flow measurement‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012 (Oral)

59. Y. Shang, L. Chen, M. Toborek, G. Yu, ―Hemodynamic monitoring of repeated cerebral ischemia in mice using diffuse optical spectroscopies‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012

60. R. Cheng*, Y. Shang, G. Yu, ―Noninvasive optical detection of spontaneous low frequency oscillations in cerebral blood flow‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012 (Oral)

61. L. Dong*, M. Kudrimoti, R. Cheng*, Y. Shang, E. L. Johnson, S. D. Stevens, B. J. Shelton, G. Yu, ―Noninvasive diffuse optical monitoring of hemodynamic changes in head and neck tumor during radiation delivery‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012

62. L. Dong*, D. Irwin*, Y. Shang, R. Cheng*, M. Kudrimoti, S. D. Stevens, and G. Yu, ―Influences of tissue optical properties on diffuse correlation spectroscopy blood flow measurements‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012

63. L. He*, Y. Lin, Y. Shang, and G. Yu, “Using few-mode fiber to improve the signal-to-noise ratio of DCS flow-oximeter measurements”, OSA Biomedical Optics (BIOMED), Miami, FL, 2012

64. G. Yu, K. Gurley*, Y. Shang, ―DCS measurement can be gated via monitoring muscle movement to derive accurate blood flow in exercising muscle‖, OSA Biomedical Optics (BIOMED), Miami, FL, 2012 (Oral)

65. L. Dong*, M. Kudrimoti, R. Cheng*, Y. Shang, E. L. Johnson, S. D. Stevens, B. J. Shelton, G. Yu, ―Noninvasive diffuse optical monitoring of hemodynamic changes in head and neck tumor during radiation delivery‖, UK Markey Cancer Research Day, Lexington, KY, 2012

66. L. He*, Y. Lin, Y. Shang, and G. Yu, ―Noncontact 3-D optical imaging of breast tumor‖, UK Markey Cancer Research Day, Lexington, KY, 2012

--2011–

67. G. Yu, Y. Shang, ―Near-infrared diffuse optical spectroscopies for measurement of deep tissue blood flow, oxygenation and metabolism‖, IEEE Biomedical Instrumentation for the Future of Instrumentation International Workshop (FIIW), Oak Ridge National Laboratory, Oak Ridge, TN, 2011 (Oral)

68. Y. Shang, K. Gurley*, B. Symons, D. Long, J. Lee, L. Crofford, C. Peterson, G. Yu, ―Diffuse optical spectroscopies for detecting hemodynamic recovery in women with fibromyalgia‖, Gill Heart Cardiovascular Research Day, Poster Section, University of Kentucky, Lexington, KY, 2011

69. R. Cheng*, Y. Shang, G. Yu, ―Noninvasive optical evaluation of spontaneous low frequency oscillations in cerebral blood flow and oxygenation‖, Gill Heart Cardiovascular Research Day, Poster Section, University of Kentucky, Lexington, KY, 2011

14

70. Y. Shang, K. Gurley*, B. Symons, D. Long, J. Lee, L. Crofford, C. Peterson, G. Yu, ―Diffuse optical spectroscopies for detecting hemodynamic recovery in women with fibromyalgia‖, UK Muscle Biology Fall Retreat, Lexington, KY, 2011

71. Y. Shang, R. Cheng*, L. Dong*, S. P. Saha, G. Yu, ―Diffuse optical evaluation of revascularization effect on ischemic muscle hemodynamics in lower extremities‖, Engineering Conferences International (ECI), Naples, FL, 2011

72. D. Irwin*, L. Dong*, Y. Shang, R. Cheng*, M. Kudrimoti, G. Yu, ―Influences of tissue absorption and scattering on diffuse correlation spectroscopy blood flow measurements‖, Engineering Conferences International (ECI), Naples, FL, 2011

73. Y. Shang*, R. Cheng*, L. Dong*, S. J. Ryan, S. P. Saha, G. Yu, ―Use of diffuse optical spectroscopies and electroencephalogram for cerebral monitoring during carotid endarterectomy‖, Engineering Conferences International (ECI), Naples, FL, 2011

74. B. Symons, N. Munk*, Y Shang, R Cheng*, and G. Yu, ―Lower limb massage increases skeletal muscle blood flow in young women‖, Annual Meeting of American College of Sports and Medicine (ACSM), Denver, CL, 2011

75. D. Irwin*, L. Dong*, Y. Shang, R. Cheng*, S. Steven, M. Kudrimoti, G. Yu, ―Influences of tissue absorption and scattering on diffuse correlation spectroscopy blood flow measurements in head and neck tumors‖, UK Markey Cancer Research Day, Lexington, KY, 2011

76. Y. Shang, R. Cheng*, L. Dong*, D. Irwin*, K. M. Gurley*, K. R. Swartz, S. S. Salles, G. Yu, ―Evaluation of electronic stimulation impact on muscle hemodynamics using diffuse optical spectroscopies‖, 23rd Annual Physical Medicine and Rehabilitation Research Day, Lexington, KY, 2011

--2010--

77. R. Cheng*, Y. Shang, G. Yu, S. P. Saha, ―Intraoperative Evaluation of Revascularization Effect on Ischemic Muscle Hemodynamics Using Near-infrared Diffuse Optical Spectroscipies‖, 52nd Annual World Congress, International College of Angiology (ICA), Lexington, KY, 2010

78. Y. Shang, R. Cheng*, L. Dong*, S. P. Saha, G. Yu, ―Detection of Cerebral Ischemia During Carotid Endarterectomy Using Near-infrared Diffuse Optical Spectroscopies‖, 52nd Annual World Congress, International College of Angiology (ICA), Lexington, KY, 2010

79. G. Yu, ―What You Can Do With Advanced NIRS Technology?‖, Annual Meeting of American College of Sports and Medicine (ACSM), Baltimore, MA, 2010

80. G. Yu, Y. Shang, Y. Zhao, R. Cheng*, L. Dong*, and D. Irwin*, ―Portable Optical Tissue Flow Oximeter Based on Diffuse Correlation Spectroscopy‖, SPIE Photonics West, San Francisco, CA, 2010

81. Y. Shang, Y. Zhao, R. Cheng*, L. Dong*, S. P. Saha, and G. Yu ―Intraoperative Assessment of Acute Revascularization Effect on Ischemic Muscle Perfusion‖, SPIE Photonics West, San Francisco, CA, 2010

82. G. Yu, Y Shang, Y. Zhao, R. Cheng*, L. Dong*, D. Irwin*, and S. P. Saha, ―Portable Optical Tissue Flow Oximeter for Evaluation of Revascularization Effect on Ischemic Muscle Hemodynamics,‖ OSA Biomedical Optics (BIOMED), Miami, FL, 2010

83. R. Cheng*, Y. Shang, D. Kameny, D. Hayes Jr, and G. Yu, ―Noninvasive Optical Evaluation of Cerebral Autoregulation in Patients with Obstructive Sleep Apnea,‖ OSA Biomedical Optics (BIOMED), Miami, FL, 2010

84. Y. Shang, R. Cheng*, L. Dong*, S. P. Saha, and G. Yu, ―Diffuse Optical Detection of Cerebral Ischemia During Carotid Endarterectomy,‖ OSA Biomedical Optics (BIOMED), Miami, FL, 2010

85. Y. Shang, Y. Zhao, R. Cheng, L. Dong*, D. Irwin*, K. R. Swartz, S. S. Salles, and G. Yu, ―Diffuse Optical Spectroscopies for Evaluation of Muscle Hemodynamic Enchantments by Electrical Stimulation,‖ OSA Biomedical Optics (BIOMED), Miami, FL, 2010

86. N. Munk*, B. Symons, Y. Shang, R. Cheng*, and G. Yu, ―Measuring the Effects of Massage on Skeletal Muscle Blood Flow: A Novel Hybrid Near-Infrared Diffuse Optical Instrument‖, Highlighting Massage Therapy in Complementary and Integrative Medicine (CIM) Research, Seattle, WA, 2010

87. R. Cheng*, Y. Shang, S. P. Saha, and G. Yu, ―Intraoperative Evaluation of Revascularization Effect on Ischemic Muscle Hemodynamics Using Near-infrared Diffuse Optical Spectroscipies‖, UK Muscle Biology Fall Retreat, Lexington, KY, 2010

88. Y. Shang, Y. Zhao, R. Cheng*, L. Dong*, D. Irwin*, K. R. Swartz, S. S. Salles, and G. Yu, ―Diffuse Optical Spectroscopies for Evaluation of Muscle Hemodynamic Enchantments by Electrical Stimulation,‖ UK Muscle Biology Fall Retreat, Lexington, KY, 2010

15

89. Y. Shang, R. Cheng*, L. Dong*, S. P. Saha, and G. Yu, ―Detection of Cerebral Ischemia During Carotid Endarterectomy Using Near-infrared Diffuse Optical Spectroscopies‖, UK Gill Heart Cardiovascular Research Day, Lexington, KY, 2010

90. R. Cheng*, Y. Shang, D. Kameny, D. Hayes Jr, G. Yu, ―Noninvasive Optical Evaluation of Cerebral Autoregulation in Patients with Obstructive Sleep Apnea,‖ UK Gill Heart Institute Cardiovascular Research Day, Lexington, KY, 2010

--2009--

91. Y. Shang, Y. Zhao, R. Cheng*, D. Irwin*, L. Dong*, K. R. Swartz, S. S. Salles, and G. Yu, "Noninvasive Assessment of Muscle Hemodynamic Enhancement by Electrical Stimulation Using Diffuse Optical Spectroscopies," BMES 2009 Annual Scientific Meeting, Pittsburgh, PA, 2009

92. Y. Zhao, Y. Shang, R. Cheng*, L. Dong*, S. P. Saha, and G. Yu, "Diffuse Optical Monitoring of Revascularization Effect on Skeletal Muscle Perfusion," BMES 2009 Annual Scientific Meeting, Pittsburgh, PA, 2009

93. R. Cheng*, Y. Shang, Y. Zhao, L. Dong*, D. Hayes, and G. Yu, "Noninvasive Diffuse Optical Evaluation of Cerebral Autoregulation‖, BMES 2009 Annual Scientific Meeting, Pittsburgh, PA, 2009

94. G. Yu, Y. Zhao, Y. Shang, R. Cheng*, L. Dong*, and S. P. Saha, "Intraoperative Evaluation of Revascularization Effect on Ischemic Muscle Perfusion," 2nd Photonics and OptoElectronics Meetings (POEM 2009), Wuhan, China, 2009

95. G. Yu, Y. Shang, Y. Zhao, R. Cheng*, D. Irwin*, L. Dong*, K. R. Swartz, and S. S. Salles, "Diffuse Optical Evaluation of Muscle Hemodynamic Responses to Electrical Stimulation," 2nd Photonics and OptoElectronics Meetings (POEM 2009), Wuhan, China, 2009

96. Y. Shang, Y. Zhao, R. Cheng*, L. Dong*, S. P. Sibu, and G. Yu ―Intraoperative Assessment of Acute Revascularization Effect on Ischemic Muscle Perfusion‖, UK Linda and Jack Gill Heart Institute Cardiovascular Research Day, Poster Section, University of Kentucky, 2009

97. Y. Shang, Y. Zhao, R. Cheng*, D. Irwin*, L. Dong*, K. R. Swartz, S. S. Salles, and G. Yu, "Noninvasive Assessment of Muscle Hemodynamic Enhancement by Electrical Stimulation Using Diffuse Optical Spectroscopies," UK Linda and Jack Gill Heart Institute Cardiovascular Research Day, Poster Section, University of Kentucky, 2009

98. R. Cheng*, Y. Shang, Y. Zhao, L. Dong*, D. Hayes, and G. Yu, "Noninvasive Diffuse Optical Evaluation of Cerebral Autoregulation‖, UK Linda and Jack Gill Heart Institute Cardiovascular Research Day, Poster Section, University of Kentucky, 2009

99. Y. Shang, Y. Zhao, R. Cheng*, L. Dong*, S. P. Sibu, and G. Yu ―Intraoperative Assessment of Acute Revascularization Effect on Ischemic Muscle Perfusion‖, Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets, University of Kentucky, 2009

100. Y. Shang, Y. Zhao, R. Cheng*, D. Irwin*, L. Dong*, K. R. Swartz, S. S. Salles, and G. Yu, "Noninvasive Assessment of Muscle Hemodynamic Enhancement by Electrical Stimulation Using Diffuse Optical Spectroscopies," Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets, University of Kentucky, 2009

101. R. Cheng*, Y. Shang, Y. Zhao, L. Dong*, D. Hayes, and G. Yu, "Noninvasive Diffuse Optical Evaluation of Cerebral Autoregulation‖, Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets, University of Kentucky, 2009

102. E. M. Buckley**, N. Cook, T. Durduran, M. Kim**, C. Zhou, R. Choe, G. Yu, D. J. Licht, J. A. Detre, J. H. Greenberg, H. Hurg, and A. G. Yodh. Cerebral Hemodynamics of Preterm Infants during Postural Intervention Measured with Diffuse Correlation Spectroscopy and Transcranial Doppler Ultrasound. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009

103. Durduran T, Kim M N**, Buckley E M**, Choe R, Zhou C, G. Yu, and Yodh A G. Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities. In SPIE Photonics West. San Jose, CA, 2009

104. Durduran T, Kim M N**, Buckley E M**, Zhou C, G. Yu, Choe R, Durning S M, Mason S, Montenegro L M, Nicholson S C, Putt M E, Zimmerman R A, Wang J, Greenberg J H, Detre J A, Yodh A G, and Licht C J. Cerebral oxygen metabolism (cmro2) reactivity to hypercapnia in neonates with severe congenital heart defects measured with diffuse optics. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009

105. Edlow B**, Kim M N**, Durduran T, Buckley E M**, Zhou C, G. Yu, Putt M E, Yodh A G, Greenberg J H, and Detre J A. The effect of healthy aging on cerebral and systemic hemodynamic responses to

16

posture change. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009

106. Kim M N**, Durduran T, Frangos S, Buckley E M**, Zhou C, G. Yu, Moss H, Edlow B L**, Maloney-Wilensky E, Detre J A, Greenberg J H, Kofke A W, Yodh A G, Grady S M, Wolf R L, and Levine J. Diffuse optical measurements of cerebral blood flow and oxygenation in patients after traumatic brain injury or subarachnoid hemorrhage. In Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. National Institutes of Health, Bethesda, MD, 2009

107. Kim M N**, Durduran T, Frangos S, Edlow B L**, Buckley E M**, Moss H, Zhou C, G. Yu, Choe R, Maloney-Wilensky E, Wolf R L, Woo J H, Grady M S, Greenberg J H, Levine J, Yodh A G, Detre J A, and Kofke W A. Non-invasive measurements of cerebral blood flow with diffuse optics in patients after severe head injury. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009

108. Kim M N**, Durduran T, Frangos S, Edlow B L**, Buckley E M**, Moss H, Zhou C, G. Yu, Choe R, Maloney-Wilensky E, Wolf R L, Woo J H, Grady S M, Greenberg J H, Levine J, Detre J A, Kofke W A, and Yodh A G. Measurements of cerebral blood flow and blood oxygenation with diffuse optics in patients after severe brain injury. In European Conferences on Biomedical Optics, OSA. Munich, Germany, 2009

109. Zhou C, Euckner S A**, Durduran T, G. Yu, Ralston J**, Friess S H, Ichord R N, Margulies S S, and Yodh A G. Diffuse optical monitoring of cerebral hemodynamics in piglet with traumatic brain injury. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009

--2008--

110. G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, F. S. Joseph, A. G. Yodh, Diffuse Optical Measurements of Prostate Blood Flow and Oxygenation During Interstitial Photodynamic Therapy, Markey Cancer Research Day, Poster Section (University of Kentucky, Oct. 2008)

111. G. Yu, Y. Zhao, D. Mukherjee, S. P. Saha, Diffuse Light Assessment of Peripheral Artery Disease (PAD) and Revascularization, Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets, Poster Section (University of Kentucky, Oct. 2008)

112. G. Yu, Y. Zhao, D. Mukherjee, S. P. Saha, Diffuse Light Assessment of Peripheral Artery Disease (PAD) and Revascularization, UK Linda and Jack Gill Heart Institute Cardiovascular Research Day, Poster Section (University of Kentucky, Oct. 2008)

113. G. Yu, Diffuse Light Assessment of Peripheral Artery Disease (PAD), 3rd Annual Clinical and Translational Science Spring Conference, Poster Section (University of Kentucky, June 2008)

114. G. Yu, C. Ahn, X. Xing**, T. Durduran, E. R. Mohler III, F. Erdman, A. G. Yodh, R, Salcido, Heat and Cold on the Back Modulate Blood Flow in Distant Skeletal Muscles, 55th annual meeting of American College of Sports and Medicine (Indianapolis IN, June 2008)

115. G. Yu, T. M. Busch, T. Durduran, C. Zhou**, X. Xing**, T. Zhu, J. C. Finlay, S. B. Malkowicz, S. M. Hahn, A. G. Yodh, Blood Flow Responses to Photodynamic Therapy with Two Photosensitizers: Photofrin and Motexafin Lutetium (MLu), OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)

116. X. Xing**, E. R. Mohler III, T. Durduran, C. Zhou**, G. Lech, A. G. Yodh, G. Yu, Diffuse Light Quantification of Peripheral Artery Disease (PAD), OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)

117. D. R. Busch, C. Zhou**, G. Yu, R. Choe, T. Durduran, M. A. Rosen, M. D. Schnall, A. G. Yodh, Effects of Compression on Transillumination Measurements of Blood Flow and Chromophore Concentrations in Human Breast Tissue, OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)

118. E. M. Buckley**, M. N. Kim**, T. Durduran, G. Yu, R. Choe, C. Zhou**, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, A. G. Yodh, Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound, OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)

119. T. Durduran C. Zhou**, B. L. Edlow**, G. Yu, R. Choe, M. N. Kim**, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, J. A. Detre, A. G. Yodh, Non-invasive Measurement of Cerebral Autoregulation of Acute Ischemic Stroke Patients with Diffuse Correlation/Wave Spectroscopy, OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)

120. M. N. Kim**, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou**, G. Yu, B. L. Edlow**, E. Mahoney-Wilensky S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical

17

Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage, OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)

121. T. Durduran, C. Zhou**, M. N. Kim**, E. M. Buckley**, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, D. J. Licht, Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects, Annual Meeting of the American Neurological Association (Salt Lake City, Utah, Sep. 2008)

122. M. N. Kim**, T. Durduran, B. L. Edlow**, C. Zhou, G. Yu, E. M. Buckley, A. G. Yodh, J. H. Greenberg, J. A. Detre, Healthy Aging Alters the Hemodynamic Response to Orthostatic Stress, International Stroke Conference (2008)

123. T. Durduran, M. N. Kim**, E. M. Buckley**, B. L. Edlow**, H. Moss, C. Zhou**, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, J. A. Detre, Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes, Annual Meeting of the American Neurological Association (Salt Lake City, Utah, Sep. 2008)

124. T. Durduran, M. N. Kim**, E. M. Buckley**, B. L. Edlow**, H. Moss, C. Zhou**, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, J. A. Detre, Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes, Annual Meeting of the American Neurological Association (Salt Lake City, Utah, Sep. 2008)

125. M. N. Kim**, T. Durduran, S. Frangos, E. M. Buckley**, C. Zhou**, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, J. Levine, Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage, Neurocritical Care Society Annual Meeting (Miami, FL, 2008)

--2007--

126. X. Xing**, E. R. Mohler III, C. Zhou**, T. Durduran, G. M. Lech, Y. Shi**, R. Wilensky, J. Moore, A. G. Yodh, G. Yu, Hemodynamic Changes in Diabetic Pig Muscle, in SVMB 18th Annual Meeting (Baltimore, MA, 2007)

127. G. Yu, T. Durduran, C. Zhou**, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, S. J. Friedberg, A. G. Yodh, Diffuse Optical Measurements of Tissue Blood Flow and Oxygenation During Clinical Prostate and Pleural Photodynamic Therapy, Proc. SPIE: on Biomedical Optics (San Jose, CA, 2007)

128. G. Yu, T. F. Floyd, T. Durduran, C. Zhou**, J. Wang, J. M. Murphy, E. R. Mohler III, A. G. Yodh, Concurrent Diffuse Optical and MRI Measurement of Blood Flow in Human Skeletal Muscle, Proc. SPIE: on Biomedical Optics (San Jose, CA, 2007)

129. X. Xing, E. R. Mohler III, C. Zhou**, T. Durduran, G. M. Lech, Y. Shi**, R. Wilensky, J. Moore, A. G. Yodh, G. Yu, Hemodynamic Changes in Diabetic Pig Muscle, Proc. SPIE: on Biomedical Optics (San Jose, CA, 2007)

130. G. Yu, T. F. Floyd, T. Durduran, C. Zhou**, J. J. Wang, J. A. Detre, A. G. Yodh, Validation of Diffuse Correlation Spectroscopy for Muscle Blood Flow with Concurrent Arterial-Spin-Labeling Perfusion MRI, 54th Annual Meeting of American College of Sports Medicine (ACSM) (New Orleans, LA, 2007)

131. J. Im, S. Smith**,, G. Yu, G. M. Lech, S. Nioka, A. G. Yodh, B. Chance, Impaired Skeletal Muscle Blood Flow, Mitochondrial Function and Exercise Capacity in Type II Diabetes with PAD: A Simultaneous NIRS and 31P-MRS Study, 54th Annual Meeting of American College of Sports Medicine (ACSM) (New Orleans, LA, 2007)

132. T. Durduran, C. Zhou**, G. Yu, B. Edlow**, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, J. A. Detre, Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position, International Stroke Conference, (San Francisco, CA 2007)

133. G. Yu, T. Durduran, C. Zhou**, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, S. J. Friedberg, A. G. Yodh, Diffuse Optical Measurements of Tissue Blood Flow and Oxygenation During Clinical Prostate and Pleural Photodynamic Therapy, 11th World Congress of the Internation Photodynamic Association (IPA), (Shanghai, China, 2007)

18

134. G. Yu, T. Durduran, C. Zhou**, H.W. Wang, M. Putt, T. M. Busch, A. G. Yodh, Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, 11th World Congress of the Internation Photodynamic Association (IPA), (Shanghai, China, 2007)

--2006--

135. G. Yu, T. Durduran, C. Zhou**, G. M. Lech, E. R. Mohler III, A. G. Yodh, Assessment of Muscle Vascular Disease with Diffuse Light, in World Congress on Medical Physics and Biomedical Engineering 2006 (Seoul, Korea, 2006)

136. G. Yu, T. Durduran, C. Zhou**, J. C. Finlay, T. C. Zhu, T. M. Busch, S. B. Malkowicz, S. M. Hahn, A. G. Yodh, Real-Time Diffuse Optical Measurements of Hemodynamic Responese to PDT in Human Prostate, in World Congress on Medical Physics and Biomedical Engineering 2006 (Seoul, Korea, 2006)

137. G. Yu, T. Durduran, C. Zhou**, G. M. Lech, E. R. Mohler III, A. G. Yodh, Diffuse Light Quantification of Blood Flow, Oxygenation and Metabolism in Human Skeletal Muscle, in American College of Sports Medicine (ACSM) (Denver, CO, 2006)

138. G. Yu, T. F. Floyd, T. Durduran, C. Zhou**, J. J., Wang, J. A. Detre, E. R. Mohler III, A. G. Yodh Concurrent Optical-MRI Measurement of Limb Blood Flow/Perfusion, in SVMB 17th Annual Meeting (Philadelphia, PA, June, 2006)

139. G. Yu, Turgut Durduran, Chao Zhou**, Jarod C. Finlay, Timothy C. Zhu, Theresa M. Busch, S. Bruce Malkowicz, Stephen M. Hahn, Arjun G. Yodh, Diffuse Optical Measurements of Tissue Blood Flow and Oxygenation during Interstitial Prostate PDT, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

140. G. Yu, T. Durduran, C. Zhou**, G. Lech, E. R. Mohler III, A. G. Yodh, Assessment of Muscle Vascular Disease with Diffuse Light, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

141. T. Durduran, G. Yu, M. G. Burnett, C. Zhou**, J. J. Wang, Q. Shah, S. Kasner, J. A. Detre, A. G. Yodh, J. H. Greenberg, Diffuse Optical Measurement of Cerebral Metabolic Rate of Oxygen In Adult Brain, in World Congress on Medical Physics and Biomedical Engineering 2006 (Seoul, Korea, 2006)

142. C. Zhou**, T. Durduran, G. Yu, S. Eucker**, S. Friess**, R. Ichor**, S. Margulies, A. G. Yodh, Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Head Trauma Injury, in World Congress on Medical Physics and Biomedical Engineering 2006 (Seoul, Korea, 2006)

143. T. Durduran, C. Zhou**, G. Yu, A. M. Hoang**, K. Z. Tang**, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurement of Local Cerebral Blood Flow, Blood Oxygenation and Metabolism During Cognitive Tasks, 12th Annual Meeting of the Organization for Human Brain Mapping (Florence, Italy, 2006)

144. C. Zhou**, T. Durduran, G. Yu, S. Eucker**, S. Friess**, R. Ichord**, S. Margulies, A. G. Yodh, Real-Time Monitoring of Hemodynamic Changes in Neonatal Pig Brain with Head Trauma Injury, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

145. R. Choe, C. Zhou**, T. Durduran, G. Yu, N. Shah, A. Durkin, A. Cerussi, B. J. Tromberg, A. G. Yodh, Neoadjuvant Chemotherapy Monitoring with Diffuse Optical Measurement of Blood Flow in Breast Tumors, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

146. Zhou C**, Durduran T, Szabados T, Yu G, Choe R, Xing X**, Greenberg JH, Durian, DJ and Yodh, AG, Noise Model for Laser Speckle Contrast Imaging, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

147. U. Sunar**, C. Zhou**, T. Durduran, G. Yu, A. G. Yodh, I. Lee, Ranpirnase Enhances Efficacy of Radiation on Human Lung Cancer Xenografts of Nude Mice Assessed by Diffuse Optical Spectroscopies, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

148. A. Sunar**, H. Quon, J. Zhang**, J. Du, T. Durduran, C. Zhou**, G. Yu, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, A. G. Yodh, Changes in Optical Blood Flow and Oxygenation of Head and Neck Tumors During Chemo-Radiation Therapy, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

149. U. Sunar**, S. Makonnen, H. W. Wang, T. Durduran, C. Zhou**, G. Yu, I. Lee, A. G. Yodh, Non-Invasive, Continuous Monitoring of a Vascular Targeting Drug by Diffuse Optical Blood Flow and Blood Oxygenation Measurements, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

150. C. Zhou**, T. Durduran, T. Szabados, O. Pascual, G. Yu, A. G. Yodh, P. G. Haydon, J. H. Greenberg, Optical Imaging of Cerebral Hemodynamic Response during Vibrissae Stimulation in Transgenic Mice Stroke Models, (Cortona, Italy, 2006)

19

--2005--

151. G. Yu, T. Durduran, C. Zhou**, G. Lech, E. R. Mohler III, A. G. Yodh, Assessment of Muscle Vascular Disease with Diffuse Light, in 2005 Workshop on Investigation of Human Muscle Function In Vivo (Nashville, Tennessee, 2005)

152. G. Yu, T. F. Floyd, J. M. Murphy, T. Durduran, C. Zhou**, A. G. Yodh, Concurrent Optical-MRI Measurement of Limb Blood Flow/Perfusion, in 2005 Workshop on Investigation of Human Muscle Function In Vivo (Nashville, Tennessee, 2005)

153. G. Yu, E. R. III Mohler, T. Durduran, C. Zhou**, G. Lech, A. G. Yodh. Simultaneous Quantification of Pulmonary and Leg Muscle VO2 during Maximal Exercise in Humans, in 2005 Workshop on Investigation of Human Muscle Function In Vivo (Nashville, Tennessee, 2005)

154. G. Yu, E. R. III Mohler, T. Durduran, C. Zhou**, G. Lech, A. G. Yodh. Simultaneous Quantification of Pulmonary and Leg Muscle VO2 during Maximal Exercise in Humans, in Society For Vascular Medicine and Biology (Chicago, 2005)

155. G. Yu, T. Durduran, G. Lech, C. Zhou**, B. Chance, E. R. Mohler III, A. G. Yodh, Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscles, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)

156. G. Yu, T. Durduran, C. Zhou**, H. W. Wang, M. Putt, T. M. Busch, A. G. Yodh, Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)

157. T. Durduran, G. Yu, M. G. Burnett, C. Zhou**, J. J. Wang, J. A. Detre, J. H. Greenberg, A. G. Yodh. Diffuse Optical Measurements of Cerebral Blood Flow, Oxygenation and Oxygen Metabolism in Adult Brain, in European Conferences on Biomedical Optics, OSA (Munich, Germany, 2005)

158. T. Durduran, G. Yu, C. Zhou**, D. Furuya, J. P. Culver, A. G. Yodh, J. H. Greenberg, Development of Diffuse Correlation Techniques for Non-Invasive Measurement of Cerebral Blood Flow and Metabolism in Rats, BRAIN 05, International Society of Cerebral Blood Flow and Metabolism (Amsterdam, NL, 2005)

159. T. Durduran, G. Yu, M. G. Burnett, C. Zhou**, J. J. Wang, J. A. Detre, A. G. Yodh, J. H. Greenberg, Diffuse Optical Measurement of Cerebral Metabolic Rate of Oxygen in Adult Brain, BRAIN 05, International Society of Cerebral Blood Flow and Metabolism (Amsterdam, NL, 2005)

160. T. Durduran, G. Yu, C. Zhou**, D. Furuya, J. A. Detre, J. H. Greenberg, A. G. Yodh, Three Dimensional Imaging of Oxygen Metabolism in Rats During Cortical Spreading Depression, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)

161. T. Durduran, G. Yu, M. G. Burnett, C. Zhou**, J. J. Wang, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurement of Cerebral Oxygenation, Flow and Oxygen Metabolism in Adult Human Brain, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)

162. C. Zhou**, T. Durduran, G. Yu, A. G. Yodh, Optimization of 3D Blood Flow Imaging by Diffuse Correlation Tomography: Signal-To-Noise Analysis, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)

163. T. Durduran, T. Shimazu, G. Yu, M. G. Burnett, C. Zhou**, J. A. Detre, J. H. Greenberg, A. G. Yodh, Characterization of the Spatio-Temporal Behavior of Cerebral Blood Flow Using Laser Speckle Flowmetry during Electrical and Mechanical Stimulation of the Forepaw and Whiskers and during Transient Forebrain Ischemia, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)

164. U. Sunar**, H. Quan, J. Zhang**, J. Du, T. Durduran, C. Zhou**, G. Yu, A. Kilger, R. Lustig, L. Loevner, S. Nioka, A. G. Yodh, B. Chance, Monitoring of Radiation Therapy Response of Head and Neck Tumors by Non-invasive Optical Blood Flow Measurements, in European Conferences on Biomedical Optics, OSA (Munich, Germany, 2005)

--2004--

165. G. Yu, T. Durduran**, G. Lech, C. Zhou**, B. Chance, E. R. Mohler, A. G. Yodh, Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscles Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies, in the Institute For Medicine AND Engineering (IME) Interdisciplinary Research Symposium 2004 (University of Pennsylvania, Philadelphia, PA, 2004)

166. G. Yu, T. Durduran**, C. Zhou**, H.W. Wang, M. Putt, A. G. Yodh, T. M. Busch, Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy, in the Institute For Medicine AND Engineering (IME) Interdisciplinary Research Symposium 2004 (University of Pennsylvania, Philadelphia, PA, 2004)

20

167. G. Yu, T. Durduran**, C. Zhou**, F. Jarod, T. Zhu, S. J. Hahn, A. G. Yodh, Real-time Diffuse Optical Measurement of Hemodynamic Responses to PDT in Human Prostate, in the Institute For Medicine AND Engineering (IME) Interdisciplinary Research Symposium 2004 (University of Pennsylvania, Philadelphia, PA, 2004)

168. G. Yu, T. Durduran**, C. Zhou**, H. W. Wang, M. Putt, T. M. Busch, A. G. Yodh, Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy, in International Conference on Tumor Progression and Therapeutic Resistance (Philadelphia, PA, 2004)

169. G. Yu, T. Durduran**, C. Zhou**, F. Jarod, T. C. Zhu, S. M. Hahn, A. G. Yodh, Real-time Diffuse Optical Measurement of Hemodynamic Responses to PDT in Human Prostate, in International Conference on Tumor Progression and Therapeutic Resistance (Philadelphia, PA, 2004)

170. G. Yu, T. Durduran**, C. Zhou**, H.W. Wang, M. Putt, T. M. Busch, A. G. Yodh, Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, in Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at NIH, (Bethesda, MA, 2004)

171. G. Yu, T. Durduran, G. Lech, C. Zhou**, B. Chance, E. R. Mohler III, A. G. Yodh, Noninvasive Quantification of oxidative metabolism in Human Skeletal Muscle Using Hybrid Near-infrared Diffuse Optical Spectroscopies, in Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at NIH, (Bethesda, MA, 2004)

172. G. Yu, T. Durduran**, C. Zhou**, H.W. Wang, M. Putt, A. G. Yodh, T. M. Busch, Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, in 32nd Annual Meeting of the American Society of Photobiology (ASP) (Seattle, WA, 2004)

173. G. Yu, T. Durduran**, G. Lech, C. Zhou**, C. Britton, A. G. Yodh, Non-Invasive Measurements of Deep Tissue Hemodynamics in Human Skeletal Muscle, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

174. G. Yu, T. Durduran**, C. Zhou**, M. Putt, A. G. Yodh, T. M. Busch, Prediction of Treatment Efficacy by Blood Flow Responses to PDT in RIF Tumors, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

175. Turgut Durduran**, G Yu, M G Burnett, C Zhou**, D Furuya, J A Detre, J H Greenberg, A G Yodh, Spatio-temporal Quantification of Cerebral Blood Flow During Forepaw Stimulation of the Rat Using Laser Speckle Flowmetry, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

176. Turgut Durduran**, G Yu, M G Burnett, C Zhou**, J A Detre, J H Greenberg, A G Yodh, Hybrid Diffuse Optical Measurements of Oxygen Metabolism in Human Brain during Sensorimotor Stimulus, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

177. C. Zhou**, T. Durduran**, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurements of Oxygen Metabolism in Human Brain during Sensorimotor Stimulus, in Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at NIH, (Bethesda, MA, 2004)

178. C. Zhou**, T. Durduran**, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, 3D in-vivo Flow Imaging by Diffuse Correlation Tomography, in Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at NIH, (Bethesda, MA, 2004)

179. M. G. Burnett, T. Durduran**, G. Yu, C. Zhou**, J. A. Detre, J. H. Greenberg, A. G. Yodh, A Novel Bedside Instrument for Non-invasive Measurement of Cerebral Hemodynamics: Development and Results of Human Testing During Cortical Sensorimotor Activation in Congress of Neurological Surgeons (San Francisco, CA, 2004)

180. C. Zhou**, T. Durduran**, G. Yu, A. G. Yodh, Optimization of 3D Flow Imaging by Diffuse Correlation Tomography, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

181. R. Choe, T. Durduran, G. Yu, J. M. Nijland, B. Chance, A. G. Yodh, Nirmala Ramanujam, Transabdominal Near-infrared Fetal Brain Oximetry, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

182. M. G. Burnett, T. Durduran**, G. Yu, C. Zhou**, J. A. Detre, J. H. Greenberg, A. G. Yodh, A Novel Bedside Instrument for Non-invasive Measurement of Cerebral Hemodynamics: Development and Results of Human Testing During Cortical Sensorimotor Activation, in Congress of Neurological Surgeons Annual Meeting (San Franciso, CA, 2004)

183. T. Shimazu, T. Durduran**, M.G. Burnett, G. Yu, A.G. Yodh, J.A. Detre, J.H. Greenberg, Acute Recovery of Functional Activation Following Forebrain Ischemia in the Rat: A Laser Speckle Study, in Neuroscience (2004)

21

184. U. Sunar**, J. Zhang**, J. Du, T. Durduran, C. Zhou**, G. Yu, A. Kilger, H. Quon, R. Lustig, L. Loevner, S. Nioka, K. Pourrezaei, A.G. Yodh and B. Chance, Clinical Responses of Head & Neck Tumors to Radiation Therapy by NIR Spectroscopy, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

--2003--

185. G. Yu, T. Durduran**, G. Lech, B. Chance, A. G. Yodh, Noninvasive Hemodynamic Measurements during Exercise and Cuff-ischemia in Human Calf Muscle, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)

186. G. Yu, T. Durduran**, T. M. Busch, C. Zhou**, A. G. Yodh, Hemodynamic Changes in RIF Tumors during and after PDT, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)

187. G. Yu, T. Durduran**, M. G. Burnett, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurements of Hemodynamics in Human Brain, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)

188. G. Yu, T. Durduran**, D. Furuya, J. H. Greenberg, A. G. Yodh, Oxygen Metabolism during Cortical Spreading Depression at Altered Ventilation States, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)

189. G. Yu, T. Durduran**, T. M. Busch, H. W. Wang, C. Zhou**, H. M. Saunders, C. M. Sehgal, A. G. Yodh, Hemodynamics in RIF Tumors during and after PDT, in 9th World Congress of The International Photodynamic Association (Miyazaki, Japan, 2003)

190. G. Yu, T. Durduran**, D. Furuya, G. Lech, C. Zhou**, B. Chance, J. H. Greenberg, A. G. Yodh, Hemodynamic Measurements in Rat Brain and Human Muscle Combining Diffuse Near-infrared Absorption and Correlation Spectroscopies, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V (San Jose, CA, 2003)

191. G. Yu, T. Durduran**, T. M. Busch, H. W. Wang, C. Zhou**, H. M. Saunders, C. M. Sehgal, A. G. Yodh, Non-invasive Monitoring Hemodynamic Responses in RIF Tumors during and after PDT, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V (San Jose, CA, 2003)

192. R. Choe**, T. Durduran**, G. Yu, M. J. Nijland, P. W. Nathanielsz, B. Chance, A. G. Yodh, N. Ramanujan, Non-invasive Cerebral Hemoglobin Oxygenation Quantification of Fetal Sheep under Hypoxic Stress In-utero using Frequency-domain Diffuse Optical Two-layer Model, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)

193. M. G. Burnett, T. Durduran**, G. Yu, A. Cardenas, J. A. Detre, J. H. Greenberg, Characterization of the Activation-flow Coupling Response during Forepaw Stimulation in the Rat using Laser Speckle Contrast Imaging, in Brain03 and Brain PET03 (Alberta, Canada, 2003)

194. T. Durduran**, G. Yu, G. Lech, C. Zhou**, B. Chance, A. G. Yodh, Noninvasive and Simulataneous Measurements of Tissue Oxygenation and Blood Flow during Exercise and Cuff-Ischemia in Human Calf Muscle, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V, (San Jose, CA, 2003)

195. T. Durduran**, G. Yu, M. G. Burnett, D. Furuya, J. A. Detre, J. H. Greenberg, A. G. Yodh, Measuring Oxygen Metabolism during Cortical Spreading Depression at Altered Carbonation States, in SPIE Photonics West (San Jose, CA, 2003)

196. C. Zhou**, T. Durduran**, G. Yu, A. G. Yodh, Optimizing Image Reconstruction of Tissue Blood Flow For Diffuse Correlation Spectroscopy, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V (San Jose, CA, 2003)

197. R. Choe**, T. Durduran**, G. Yu, J. M. Nijland, P. W. Nathanielsz, B. Chance, A. G. Yodh, N. Ramanujam, Non-invasive Cerebral Hemoglobin Oxygenation Quantification of Fetalmsheep under Hypoxic Stress In-utero Using Frequency-domain Diffuse Optical Two-layer Model, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V (San Jose, CA, 2003)

--2001 to 2002--

198. G. Yu, T. Durduran**, D. Furuyab, J. H. Greenberg, and A. G. Yodh, Hemodynamic Measurements in Rat Brain Combining Diffuse Near-infrared Absorption and Correlation Spectroscopies, in Proc. SPIE: Progress in Biomedical Optics and Imaging (Shanghai, China, 2002)

199. G. Yu, T. Durduran**, D. Furuyab, J. H. Greenberg, and A. G. Yodh, Diffuse Optical Multiplexing System in Frequency Domain for in vivo Monitoring of Rapid Hemodynamics, in Twenty-First Southern Biomedical Engineering Conference: Biomedical Engineering: Recent Developments (Washington DC, MA, 2002)

22

200. G. Yu, T. Durduran**, D. Furuya, R. Choe**, J. H. Greenberg, A. G. Yodh, Frequency Domain Diffuse Optical Multiplexing System for Rapid Hemodynamics, in OSA Technical Digest (Optical Society of American, Miami, FL, 2002)

201. T. Durduran**, G. Yu, J. P. Culver, C. Cheung, D. Furuya, J. H. Greenberg, A. G. Yodh, Hemodynamics of Cortical Spreading Depression and Forepaw Stimulation, in OSA Technical Digest (Optical Society of American, Miami, FL, 2002)

202. T. Durduran**, G. Yu, D. Furuya, R. Choe**, J. P. Culver, C. Cheung, J. H. Greenberg, A. G. Yodh, Effects of Duration, Hypoxia and Hypercapnia on Rat Brain Hemodynamics during Forepaw Stimulation, in OSA Technical Digest (Optical Society of American, Miami, FL, 2002)

203. T. Durduran**, G. Yu, J. P. Culver, C. Cheung, D. Furuya, J. H. Greenberg, A. G. Yodh, Hemodynamics of Cortical Spreading Depression and Forepaw Stimulation, in OSA Technical Digest (Optical Society of American, Miami, FL, 2002)

204. T. Durduran**, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, Measuring Oxygen Metabolism during Somatosensory Cortex Activation by Forepaw Stimulation in Rat Brains under Different Physiological Conditions, in ISOTT 2002 (Manchester, UK, 2002)

205. T. Durduran**, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, In Vivo Measurements of Brain Hemodynamics in Rat Brain using Diffuse Optical Tomography and Diffuse Correlation Spectroscopy, in American Physical Society (Indianapolis, IN, 2002)

206. T. Durduran**, G. Yu, D. Furuya, R. Choe, J. P. Culver, C. Cheung, J. H. Greenberg, A. G. Yodh, In Vivo Measurements of Cerebral Hemodynamics in Rats using Diffuse Optical Tomography and Diffuse Correlation Spectroscopy: Instrumentation & Results, in Gordon Research Conference (New Hampshire, 2002)

207. J. H. Greenberg, D. Furuya, T. Durduran**, G. Yu, J. A. Detre, A. G. Yodh, The Effect of Carbon Dioxide on the Hemodynamic and Metabolic Response to Cortical Spreading Depression, in Program No. 581.9, Abstract Viewer/Itinerary Planner (Washington DC: Society for Neuroscience, 2002)

208. T. Durduran**, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, In Vivo Measurements of Rat Brain hemodynamics using Diffuse Optical Tomography and Diffuse Correlation Spectroscopy, in Chalk-Talk Series, Institute of Medicine and Engineering, University of Pennsylvania (Philadelphia, PA, 2001)

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ADVISEES/MENTORS Graduate Students (9): Lixin Dong Ph.D. Student at BME Lian He Ph.D. Student at BME (Awarded UK dissertation year fellowship in 2014) Mingjun Zhao Ph.D. Student at BME Ahmed Bahrani Ph.D. Student at BME Daniel Irwin Ph.D. Student at BME (Awarded NIH pre-doctoral fellowship) Ran Cheng Ph.D. Student at BME (BME best student in 2013, graduated) Katelyn Gurley M.S. Student at BME (Graduated in 2012) Weikai Kong M.S. Student at BME Brad A. Henry M.S. Student at BME Postdoctoral Scholars (4): Yu Shang Awarded AHA postdoctoral fellowship (2011-2013) Yu Lin Chong Huang Ting Li (2012-2013) Associate Professor at University of Electronic Science & Technology of

China (UESTC), China Visiting Scholars (6): Jian Zhang (2013-2014) Associate Professor, Tianjin University of Technology and Education,

China Yajun Hou (2012-2013) Professor, Shenyang Ligong University, China Xiuling Luan (2012-2013) Professor, Dalian Stomatological Hospital, China Yanli Qin (2012-2013) Associate Professor, Shenyang Ligong University, China Aulia Nasution (2011-2012) Professor, ITS Surabaya University, Indonesia Youquan Zhao (2008-2009) Associate Professor, Tianjin University, China Clinical Coordinator (1): Dan Kameny (2010-2011) M.D.