gnipst bulletin 30.3
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22nd
November , 2013 Volume No.: 30 Issue No.
Contents Message from GNIPS
Letter to the Editor News Update
Health awareness
Disease Outbreak Ne
Forth Coming Events
Drugs Update
Campus News
Students Section
Editors Note
Archive
Vision
TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O
PHARMACEUTICAL AND BIOLOGICAL SCIENCE
EDITOR: Soumya BhattacharyaGURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND
TECHNOLOGY
GNIPST Photo Gallery
For your comments/contributionORFor ack-Issues,
mailto:[email protected]
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young children in developing countries, killing more than HIV/AIDS,
malaria and measles combined, and resulting in 1 death every 20
seconds.Read more
Two Human Proteins Found to Affect How
'Jumping Gene' Gets Around(21stNovember, 2013)
Using a new method to catch elusive "jumping genes" in the act,
researchers have found two human proteins that are used by one type
of DNA to replicate itself and move from place to place.Read more
Genomic Variant Associated With Sun Sensitivity(21st November, 2013)
Researchers have identified a genomic variant strongly associated
with sensitivity to the sun, brown hair, blue eyes -- and freckles. In
the study of Icelanders the researchers uncovered an intricate
pathway involving the interspersed DNA sequence, or non-coding
region, of a gene that is among a few dozen that are associated with
human pigmentation traits.Read more
Intranasal Insulin improves cognitive function in
patients with Type 2 Diabetes (13thNovember, 2013)
The link between type 2 diabetes and dementia has become widely
recognized. a small proof-of-concept study led by investigators atBeth Israel Deaconess Medical Center (BIDMC) offers promise of a
new treatment for this widespread problem. Currently published on-
line in the journal Diabetes Care, the study results show that a single
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dose of intranasal insulin can help improve cognitive function in
patients with diabetes.Read more
Breathalyzer Technology Detects Acetone Levels to
Monitor Blood Glucose in Diabetics(13thNovember, 2013)
A novel hand-held, noninvasive monitoring device that uses
multilayer nanotechnology to detect acetone has been shown to
correlate with blood-glucose levels in the breath of diabetics. This
research is being presented at the 2013 American Association of
Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition,
the worlds largest pharmaceutical sciences meeting, in San Antonio,Nov. 1014.Read more
Risk of heart attack, stroke among diabetes
patients significantly lower after gastric bypass(13thNovember, 2013)
New research from the Cleveland Clinic shows most patients with
diabetes and obesity who undergo gastric bypass not only experienceremission of their diabetes and lose significant weight, but they also
reduce their risk of having a heart attack by 40 percent and their risk
for suffering a stroke by 42 percent, over a 10-year time horizon. This
study emphasizes that gastric bypass dramatically changes the
trajectory of many chronic diseases associated with diabetes and
improves multiple cardiovascular risk factors in the long term.Read
more
Newly Identified Brown Fat Stem Cells Hold
Possibilities for Treating Diabetes, Obesity (21stNovember, 2013)
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Obesity and diabetes have become a global epidemic leading to severe
cardiovascular disease. Researchers at the University of Utah believe
their recent identification of brown fat stem cells in adult humans
may lead to new treatments for heart and endocrine disorders,
according to a new study published in the peer-reviewed journal Stem
Cells.Read more
HEALTH AWARENESSTrachoma-a leading cause of blindness
Trachoma is the leading cause of infectious blindness in the world. It
is caused by an obligate intracellular micro-organism called Chlamydia
trachomatis. The disease is transmitted through contact with eye and
nose discharge of infected people, particularly young children who
form the reservoir of infection. It is also spread by flies which have
been in contact with the eyes and nose of infected people.
Clinical characteristics and morbidity
In areas where trachoma is endemic active trachoma is common
among preschool-aged children, with prevalence rates which might be
as high as 60-90%. The infection becomes less frequent and shorter in
duration with increasing age. Infection is usually acquired throughliving in close proximity to a person with the active disease, and the
family is the principal unit for transmission.
After years of repeated infection, the inside of the eyelid can become
so severely scarred (conjuctival scarring) that it turns inwards and
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the eyelid border causes the eye-lashes to rub against the eyeball
(trichiasis) resulting in severe discomfort and pain; this and other
alterations of the eye can lead to the scarring of the cornea. Left
untreated, this condition leads to the formation of irreversible
opacities with resulting visual impairment and blindness typically
between the ages 30-40.
Visual impairment and blindness results in a worsening of the life
experience of individuals and their families, which are normally
already among the poorest of the poor. Women are blinded 2 to 3
times more often than men, probably due to their close contact with
affected children.
Environmental risk factors influencing the transmission of the disease
include:
poor hygiene;
crowded households;
water shortage; and
inadequate latrines and sanitation facilities.
Distribution
Trachoma is hyperendemic in many of the poorest and most rural
areas of 53 countries of Africa, Asia, Central and South America,
Australia and the Middle East.
It is responsible for approximately 1% of the worlds blindness and forthe visual impairment of about 2.2 million people, of whom 1.2 million
are irreversibly blind.
Overall, Africa remains the most affected continent and the one with
the most intensive control efforts. In 2012, 45 million people were
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treated with antibiotics and 155 thousand cases of trichiasis )were
operated in 29 endemic countries of WHOsAfrica Region.
A number of countries have reported achieving intervention goals,
which signify the end of the campaign to trachoma elimination andthe move to post-endemic surveillance. These countries are: The
Gambia, Ghana, Iran, Morocco, Myanmar, Oman and Viet Nam.
Last year the United Kingdoms Department for International
Development provided funding to a project aiming to complete the
mapping of trachoma endemic areas by 2015. The Australian
Government Overseas Aid Programme is funding the elimination ofblinding trachoma in the South East Asia Region.
Economic impact
The burden of trachoma on affected individuals and communities is
enormous. The economic cost in terms of lost productivity is
estimated at between US$2.9 and US$ 5.3 billion annually, increasing
to US$ 8 billion when trichiasis is included.
Prevention and control
Control programmes in endemic countries are being implemented
through the WHO recommended SAFE strategy. This consists of:
surgery to treat the blinding stage of the disease (trachomatous
trichiasis or TT);
antibiotics to treat infection from chlamydia trachomatis;
facial cleanliness, to educate the at risk population on the preventive
measures; and
environmental improvements, such as providing access to safe water
and improved sanitation.
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Most endemic countries have agreed to accelerate the implementation
of this strategy to achieve their respective elimination targets, all
within the year 2020.
Data reported to WHO by Member States in 2012 shows that about45 million people in endemic communities were treated with
antibiotics to eliminate trachoma. the number of people who are
reported as receiving surgery for trichiasis is in the order of 169
thousands, the highest recorded so far.
Elimination efforts need to continue to satisfy the target set by the
World Health Assembly resolution (WHA 51.11), including thecooperation of other health sectors such as sanitation sector and socio
economic development sector, in order to achieve the goal of
GET2020.
Some Facts of Diabetes
About 347 million people worldwide have diabetes.
There is an emerging global epidemic of diabetes that can be traced
back to rapid increases in overweight, obesity and physical inactivity.
Diabetes is predicted to become the seventh leading cause of
death in the world by the year 2030.
Total deaths from diabetes are projected to rise by more than 50% inthe next 10 years.
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There are two major forms of diabetes.
Type 1 diabetes is characterized by a lack of insulin production and
type 2 diabetes results from the body's ineffective use of insulin.
A third type of diabetes is gestational diabetes.
This type is characterized by hyperglycaemia, or raised blood sugar,
which has first appeared or been recognized during pregnancy.
Type 2 diabetes is much more common than type 1 diabetes.
Type 2 accounts for around 90% of all diabetes worldwide. Reports oftype 2 diabetes in children previously rare have increased
worldwide. In some countries, it accounts for almost half of newly
diagnosed cases in children and adolescents.
Cardiovascular disease is responsible for between 50% and 80% of
deaths in people with diabetes.
Diabetes has become one of the major causes of premature illness anddeath in most countries, mainly through the increased risk of
cardiovascular disease (CVD).
In 2004, an estimated 3.4 million people died from consequences of
high fasting blood sugar.
80% of diabetes deaths occur in low- and middle-income
countries.
In developed countries most people with diabetes are above the age of
retirement, whereas in developing countries those most frequently
affected are aged between 35 and 64.
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Diabetes is a leading cause of blindness, amputation and kidney
failure.
Lack of awareness about diabetes, combined with insufficient access
to health services and essential medicines, can lead to complicationssuch as blindness, amputation and kidney failure.
Type 2 diabetes can be prevented.
Thirty minutes of moderate-intensity physical activity on most days
and a healthy diet can drastically reduce the risk of developing type 2
diabetes. Type 1 diabetes cannot be prevented.
(Based on WHO database)
DISEASE OUTBREAK NEWS
Wild poliovirus in Cameroon(21st November,2013)Wild poliovirus type 1 (WPV1) has been confirmed in Cameroon, the
first wild poliovirus in the country since 2009. Wild poliovirus was
isolated from two acute flaccid paralysis (AFP) cases from West
Region. The patients developed paralysis on 1 October and 19 October
2013. Genetic sequencing indicates that these viruses are linked towild poliovirus last detected in Chad in 2011.Read more
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FORTHCOMING EVENTS
The 2nd Pharm. Tech IAPST International Conference on "New insights into
diseases and recent therapeutic approaches"from 17th to 19th January 2014 in
Kolkata, India.Read more
DRUGS UPDATES
FDA approves Nexavar to treat type of thyroid cancer(22nd November, 2013)
The U.S. Food and Drug Administration today expanded the
approved uses of Nexavar (sorafenib) to treat late-stage (metastatic)
differentiated thyroid cancer.Read more
CAMPUS NEWS
B.Pharm 3rd year won the GNIPST Football Champions trophy,2013. B.Pharm 3rdyear won the final match 1-0 against B.Pharm 2nd
year. Deep Chakrabortywas the only scorer of the final.
Students of GNIPST organized pre puja celebration programme,
Saaranya on 7thOctober, 2013 in college Auditorium.
GNIPST organized a garment distribution programme on 28thSeptember, 2013 at Dakshineswar Kali Temple and Adyapith,
Kolkata. On this remarkable event about hundred people have
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received garments. More than hundred students and most of the
faculties participated on that day with lot of enthusiasm.
GNIPST celebrated World Heart Day (29th September) andPharmacists Day(25thSeptember) on 25thand 26thSeptember,
2013 in GNIPST Auditorium. A seminar on Violence against
woman and female foeticide was held on GNIPST Auditorium on
25th September organized by JABALA Action Research
Organization. On 26thSeptember an intra-college Oral and Poster
presentation competition related to World Pharmacists day and
Heart day was held in GNIPST. Ms. Purbali Chakraborty of
B.Pharm 4th year won the first prize in Oral Presentation. Thewinner of Poster presentation was the group of Ms. Utsa Sinha,
Mr. Koushik Saha and Mr. Niladri Banerjee(B.Pharm 4thyear). A
good number of students have participated in both the competition
with their valuable views.
STUDENTS SECTION
WHO CAN ANSWER FIRST????
Which Indian won the Dan David prize along
with R.Langer and G. Whitesides in 2005?
Which prize is given in the field of past, present& future?
Answer of Previous Issues QuestionsA) Honey B)Human insulin
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Identify the personality
Answer of Previous Issues ImageFrederick Banting and Charles Best, discoverer of insulin
Solve the Puzzle
9 4 5
12 16 15
15 20 25
180 80 ?
a) 125 b) 75 c) 20 d) 25
Answer of Previous Issues PuzzleHGSOT
Send your thoughts/ Quiz/Puzzles/games/write-ups or any other contributions for StudentsSection answers of this Section [email protected]
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EDITORS NOTEI am proud to publish the 3
rd issue of 30
thVolume of GNIPST
BULLETIN. GNIPST BULLETIN now connected globally through
facebook account GNIPST bulletin
I want to convey my thanks to all the GNIPST members and the
readers for their valuable comments, encouragement and supports.
I am thankful to Dr. Abhijit Sengupta, Director of GNIPST for his
valuable advice and encouragement. Special thanks to Dr. PreronaSahaand Mr. Debabrata Ghosh Dastidarfor their kind co-operation
and technical supports. I am thankful to Mr. Subha Bhattacharjee
for his contribution tosolve the puzzle section .An important part of
the improvement of the bulletin is the contribution of the readers. You
are invited to send in your write ups, notes, critiques or any kind of
contribution for the forthcoming special and regular issue.
ARCHIVE
Teachers daywas celebrated on 5thSeptember, 2013 by the
students of GNIPST in GNIPST Auditorium.
A zalea exotic flower ) , the fresher welcome programme fornewcomers of GNIPST in the session 2013-14 was held on 8th
August in GNIPST Auditorium.
One day seminar cum teachers development programme forschool teachers on the theme of Recent Trends of Life Sciences
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in Higher Education organized by GNIPST held on 29th June,
2013 at GNIPST auditorium. The programme was inaugurated by
Prof . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy
Director of JIS Group and Dr. Abhijit Sengupta, Director cumPrincipal of GNIPST with lamp lighting. The programme started
with an opening song performed by the B.Pharm students of this
institute. The seminar consists of a series of lectures, video
presentations and poster session. On the pre lunch session 4
lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata
Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty
respectively. On their presentation the speakers enlighten the
recent development of Pharmacy, Genetics and Microbiology andtheir correlation with Life Sciences. On the post lunch session, Ms.
Saini Setua and Ms. Sanchari Bhattacharjee explained the recent
development and career opportunities in Biotechnology and
Hospital Management. The programme was concluded with
valedictory session and certificate distribution.
About 50 Higher secondary school teachers from different
schools of Kolkata and North& South 24 Parganas district ofWest Bengal participated in this programme. A good interactive
session between participants and speakers was observed in the
seminar. The seminar was a great success with the effort of
faculties, staffs and students of our Institute. It was a unique
discussion platform for school teachers and professional of the
emerging and newer branches of Life Science.
The following B.Pharm. final year students have qualified,
GPAT-2013. We congratulate them all.
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The general body meeting of APTI, Bengal Branch has been conducted
at GNIPST on 15th June, 2012. The program started with a nice
presentation by Dr. Pulok Kr. Mukherjee, School of Natural Products,
JU on the skill to write a good manuscript for publication in impact
journals. It was followed by nearly two hour long discussion amongmore than thirty participants on different aspects of pharmacy
education. Five nonmember participants applied for membership on
that very day.
GNIPST is now approved by AICTE and affiliated to WBUT for
conducting the two years post graduate course (M.Pharm) in
P H A R M A C O L O G Y .The approved number of seat is 18.The number of seats in B.Pharm. has been increased from 60 to 120.
AICTE has sanctioned a release of grant under Research Promotion
Scheme (RPS) during the financial year 2012-13to GNIPST as per the
details below:
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a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical
Science & Technology.
b.Principal Investigator:Dr. LopamudraDutta.
c. Grant-in-aid sanctioned:Rs. 16,25000/- onlyd.Approved duration: 3 years
e. Title of the project: Screening and identification of potential
medicinal plant of Purulia & Bankura districts of West Bengal with
respect to diseases such as diabetes, rheumatism, Jaundice,
hypertension and developing biotechnological tools for enhancing
bioactive molecules in these plants.