genetics and heredity chapter 5. genetics and heredity heredity- the passing of traits from parents...
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GENETICS AND HEREDITY
Chapter 5
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Genetics and Heredity
Heredity- the passing of traits from parents to offspring
Genetics- the study of how traits are passed from parents to offspring
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Gregor Mendel
Considered the Father of GeneticsAustrian MonkHe studied pea plants because they have a
wide variety of traits Pea plants also are readily available and have
a relatively short life spanHe could also control pollination
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Mendel Laws
Law of Segregation- each allele separates from the other allele independently
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Dominant and Recessive
Dominant- a genetic factor that blocks another genetic factor Only one copy of the gene is necessary for expression of
the trait “Stronger”
Recessive- A genetic factor that is blocked by the presence of a dominant factor Two copies of the trait are necessary for expression of
the trait Hidden, may appear to “skip generations”
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Understanding inheritance
Mendel concluded that one gene (factor) from each parent controlled each trait
We know these factors to genes.Genes are located on chromosomesHumans have 46 total or 23 pairs22 pairs are the autosomal chromosomes23 pair determines the sex of the individualMaleXY Female XX
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Genes and alleles
Gene- a section on a chromosome that has genetic information for a trait
Allele- the different forms of a gene are called the alleles R- for round r- wrinkled
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Genotype and Phenotype
Genotype- the genetic makeupThe two alleles that control the phenotype of the
triat
Phenotype- the physical appearanceHow the trait appears or is expressed
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Homozygous and Heterozygous
Homozygous- when the two alleles of the gene are the same RR, rr Purebred
Heterozygous- If the two alleles are different Rr Hybrid
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Modeling inheritance
Punnett square- a model used to predict genotypes and phenotypes of the offspring
Pedigree- family tree showing the phenotype of the family members. Can be used to infer genotypes
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Complex patterns of inheritance
Incomplete dominance- some traits appear to be a combination of allelesA red flower camellia plant with a white flower camellia only
produces pink flowers
Codominance- When both alleles can be observed in the offspring Cows- both red and white traits
Multiple Alleles- More than two alleles for a trait ABO blood groups
Polygenic inheritance- a combination of many genes and usually some environmental factor (can be unknown) Hair color, skin color, cleft lip, club foot
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DNA and Genetics
Genes provide the instruction or blueprint for making an organism
DNA- organisms genetic materialDNA codes for the genesDNA is tightly coiledIt is a double helix structure or twisted
ladder or zipperDiscovered by Watson and Crick
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DNA
It is composed of three partsA sugar- deoxyriboseA phosphate groupA nitrogen baseThere are four common nitrogen basesAdenine- (A) pairs with Thymine (T)Cytosine (C) pairs with Guanine (G)
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DNA replication
Replication- process of copying a DNA molecule to make another DNA molecule
1. DNA strand separates and nitrogen bases are exposed
2. Nucleotides move in and form new nitrogen bases
3. Two new identical strands are madeAlmost like a zipper opening
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Making proteins
Made with the help of Ribonucleic acid (RNA)RNA is single strandedRNA has nitrogen base Uracil (U) rather than
Thymine (T)Sugar is riboseTranscription- making mRNA (messenger
RNA) from DNA
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Translation
The process of making proteins from RNA is called translation
There are 2 other types of RNA tRNA- transfer RNA rRNA- ribosomal RNA Translation
tRNA carries amino acids to the proteins mRNA helps form chemical bonds that attach one amino
acid to another The first tRNA separates from its amino acid and mRNA. The cycle continues.
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Translating the RNA code
The order of the nitrogen bases in the mRNA determines the order of the amino acids in the protein
Three nitrogen bases are read to pick up the correct amino acid
Three nitrogen bases= codon64 codons but only 20 amino acidsSome code for the same amino acid, some code
for a stop, and some code for the beginning.
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Mutations
A mutation is a change in the nucleotide sequence of a gene
Most mutations are corrected during replication
Mutations can be triggered by X-rays, UV light, chemicals, and radioactive materials
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Types of mutations
Deletion- one or more nitrogen bases are left out of the DNA sequence
Insertion- one or more nitrogen bases are added to the DNA
Substitution- a nitrogen base is replaced by another different nitrogen base.
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Results of mutations
Not all mutations are harmful, some help an organism survive a change in environment
Some will cause a genetic disease or disorder like cystic fibrosis or PKU.