genetic variation interest grabber yes, no, or maybe some traits, such as a widow’s peak, fall...
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Genetic Variation
Interest Grabber
Yes, No, or Maybe
Some traits, such as a widow’s peak, fall into neat categories: You either have a widow’s peak or you don’t. Other traits, such as height, aren’t so easy to categorize.
Section 16-1
Genetic Variation
Interest Grabber continued
1. Make a list of physical traits that you think are influenced by genes.Then, write next to each trait whether you have the trait or not(e.g., a widow’s peak) or whether there are many variations of the trait (e.g., hair color).
2. Are most of the traits you listed clear-cut or are they mostly traitsthat have many variations? Which traits in your list are difficult tocategorize?
3. Compare your list with that of another student. Did he or she think of any traits that you missed? Why do you think some traits are clear-cut, while others are not?
Section 16-1
Genetic Variation
Section Outline
Genes and VariationA. Darwin’s Ideas Revisited
B. Gene Pools
C. Sources of Genetic Variation
1. Mutations
2. Gene Shuffling
D. Single-Gene and Polygenic Traits
Section 16-1
Genetic Variation
Review of Natural Selection
• Natural Selection - 5 Major Elements
1) All species have genetic variation.
2) The environment presents many different challenges to an individual's survival
3) Organisms tend to produce more offspring than their environment can support : thus, individuals of a species often compete with one another to survive (struggle for survival)
Genetic Variation
4) Survival of fittest : Individuals who are better able to cope with the challenges of their environment tend to leave more offspring than those less suited to the environment
5) The characteristics (genes) of the individual best suited to an environment tend to increase in a population over time
Genetic Variation
Review
EVOLUTION –
change in a population’s genes/traits over time
NATURAL SELECTION –
mechanism of evolution in which individuals with better adaptations (traits) for their environment are more likely to survive and reproduce, contributing their traits to the next generation
ALLELES –
different expressions of same gene for a single trait
Genetic Variation
A. Modern Evolution Theory
Darwin did not know about genetics.
Today evolution is expressed in genetic terms because natural selection acts on the heritable traits of organisms which we know to be the result of their GENES.
Natural selection (environmental pressures) determines which, if any, allele is favorable
Genetic Variation
KEY CONCEPT A population shares a common gene pool.
Genetic Variation
1. Population Genes
Gene Pool– common group of genes shared by a population
• **All of the alleles in all of the individuals that make up a population
• where a population’s
genetic variation is stored (next generation draws from pool).
Genetic Variation A. Population Genes
**Gene frequency – how much each allele is present within a population’s gene pool– Also allele frequency or relative frequency
Gene frequency is a percentage
= # of alleles / total alleles in population
Bb
BBbb
Genetic Variation
a) Determine which alleles in gene pool.
b) List alleles for population.
c) Count how many of each allele = # each allele.
d) Add up all alleles = total # of alleles (2 x pop. size)
e) GF = # each allele/total # of alleles
1) Calculating Gene FrequencyFrequency of Alleles “b” “B”
Population = 25 mice
BbBB
bb
12 mice
9 mice
4 mice
Genetic Variation
**Genetic variation in a population increases the chance that some individuals will survive.
• Genetic variation leads to phenotypic variation.• **Phenotypic variation is necessary for natural selection.• Genetic variation is stored in a population’s gene pool.
– made up of all alleles in a population– allele combinations form when organisms have offspring
Genetic Variation
• **Allele frequencies measure genetic variation.
– measures how common allele is in population– can be calculated for each allele in gene pool– Frequency: #of specific allele/total alleles for trait
Genetic Variation
**Genetic variation comes from several sources.
• Mutation is a random change in the DNA of a gene.
• Recombination forms new combinations of alleles.
– can form new allele– can be passed on to offspring if in reproductive cells
– usually occurs during meiosis – parents’ alleles arranged in new ways in gametes
Genetic Variation
Genetic variation comes from several sources.
• Hybridization is the crossing of two different species.– occurs when individuals can’t find mate of own
species– topic of current scientific research
Genetic Variation
Sources of Genetic Variation
Lateral Gene Transfer – genes swapped between cells without sex
– Esp. important to single-celled organisms– Transformation - Griffith’s experiment; antibiotic
resistance– Viruses (HIV), bacteriaphages
Genetic Variation
Checkpoint
1. Modern evolution is explained using which field of biology?
2. What is a population’s gene pool?
3. Define gene frequency?
4. If a population has 2 BB mice, 6Bb mice and 2 bb mice; what is the gene frequency of B?
5. Where does genetic variation in populations come from?
17ANY QUESTIONS?
Genetic Variation
Interest Grabber• . . . All the Help I Can Get
Natural selection operates on traits in different ways. You might be ableto predict which traits natural selection would favor if you think about the demands of an organism’s environment.
1. Choose an animal that you know something about, such as a deer, and write its name at the top of a sheet of paper. Then, divide your paper into two columns, and write the heading Trait in one column and Advantage in the other.
2. Under Trait, write in several of the animal’s traits.
3. Under Advantage, write in how you think the trait would be helpful to the animal.
Genetic Variation
Section Outline
Evolution as Genetic ChangeA. Natural Selection on Single-Gene Traits
B. Natural Selection on Polygenic Traits
1. Directional Selection
2. Stabilizing Selection
3. Disruptive Selection
C. Genetic Drift
D. Evolution Versus Genetic Equilibrium
1. Random Mating
2. Large Population
3. No Movement Into or Out of the Population
4. No Mutations
5. No Natural Selection
Section 16-2
Genetic Variation
KEY CONCEPT Populations, not individuals, evolve.
Genetic Variation
Founder Effect
Change in allele frequency as a result of migration by a small group
Hardy Weinberg Principle
Allele frequencies in a population will remain constant unless factors cause change
Genetic Equilibrium
Situation in which allele frequencies remain constant
**Phenotypic Distribution
Distribution curve of phenotypes, genetic drift
Genetic Variation
Directional Selection
When Natural selection forces the distribution of traits to move to one end.
Stabilizing Selection
When Natural selection forces the distribution of traits toward the center
Disruptive Selection
When Natural selection forces a split at either end.
Genetic Drift
Random changes in allele frequencies that occurs in small populations
Genetic Variation
KEY CONCEPT Natural selection is not the only mechanism through which populations evolve.
Genetic Variation
Natural Selection: environmental pressures change the gene pool
1) Selection causes an increased frequency of the most favorable allele.
Changing the Gene Pool
Genetic Variation
Gene flow is the movement of alleles between populations.
• Gene flow occurs when individuals join new populations and reproduce.
• Gene flow keeps neighboring populations similar.
• Low gene flow increases the chance that two populations will evolve into different species.
bald eagle migration
Genetic Variation
Genetic drift is a change in allele frequencies due to chance.
• Genetic drift causes a loss of genetic diversity.• It is most common in small populations.• A population bottleneck can lead to genetic drift.
– It occurs when an eventdrastically reducespopulation size.
– The bottleneck effect isgenetic drift that occursafter a bottleneck event.
Genetic Variation
Genetic Drift
• Creates small populations = small gene pool so lower genetic diversity and fewer traits available for adaptation
• often leads to extinction
Genetic Variation
Sample of Original Population
Founding Population A
Founding Population B
Descendants
Genetic DriftSection 16-2
Genetic Variation
Sample of Original Population
Founding Population A
Founding Population B
Descendants
Genetic DriftSection 16-2
Genetic Variation
Sample of Original Population
Founding Population A
Founding Population B
Descendants
Genetic DriftSection 16-2
Genetic Variation
• The founding of a small population can lead to genetic drift.
– It occurs when a few individuals start a new population.– The founder effect is genetic drift that occurs after start
of new population.
Genetic Variation
• Genetic drift has negative effects on a population.
– less likely to have some individuals that can adapt – harmful alleles can become more common due to
chance
Genetic Variation
Sexual selection occurs when certain traits increase mating success.
• Sexual selection occurs due to higher cost of reproduction for females.– males produce many
sperm continuously– females are more
limited in potential offspring each cycle
Genetic Variation
• There are two types of sexual selection.
– intrasexual selection: competition among males– intersexual selection: males display certain traits to
females
Genetic Variation
Balancing Selection = selection that acts in opposite directions
1) tends to eliminate the sickle cell gene because it is lethal to homozygous individual
2) tends to preserve the sickle cell gene because
heterozygous individual is resistant to malaria
Thus even defective genes will remain in a population as long as the benefit outweighs the cost.
Genetic Variation
Directional Selection = causes a gene to become either more or less common due to the environment.
Example: sickle cell gene becoming less common
among African Americans since malaria no longer occurs in North America.
When natural selection is unopposed, frequency of a particular gene tends to go in one direction only (elimination)
EX: peppered moth
Genetic Variation
Natural selection acts on distributions of traits.
• **A normal distribution graphs as a bell-shaped curve.
• **Traits not undergoing natural selection have a normal distribution.
– highest frequency near
mean value– frequencies decrease toward each extreme value
Genetic Variation
Natural selection can change the distribution of a trait in one of three ways.
• Microevolution is evolution within a population.– observable change in the allele frequencies – can result from natural selection
Genetic Variation
• Natural selection can take one of three paths.
– **Directional selection favors phenotypes at one extreme.
Genetic Variation
– **Stabilizing selection favors the intermediate phenotype.
• Natural selection can take one of three paths.
Genetic Variation
• Natural selection can take one of three paths.
– **Disruptive selection favors both extreme phenotypes.
Genetic Variation
KEY CONCEPT Hardy-Weinberg equilibrium provides a framework for understanding how populations evolve.
Genetic Variation
Hardy-Weinberg equilibrium describes populations that are not evolving. • Biologists use models to study populations.• Hardy-Weinberg equilibrium is a type of model.
Genetic Variation
Hardy-Weinberg equilibrium describes populations that are not evolving. • Genotype frequencies stay the same if five conditions are
met.– very large population: no genetic drift – no emigration or immigration: no gene flow – no mutations: no new alleles added to gene pool– random mating:
no sexual selection– no natural selection:
all traits aid equallyin survival
Genetic Variation
Hardy-Weinberg equilibrium describes populations that are not evolving. • Real populations rarely meet all five conditions.
– Real population data iscompared to a model.
– Models are used tostudying how populationsevolve.
Genetic Variation
The Hardy-Weinberg equation is used to predict genotype frequencies in a population.
• Predicted genotype frequencies are compared with actual frequencies.– used for traits in simple dominant-recessive systems– must know frequency of recessive homozygotes– p2 + 2pq + q2 = 1
Genetic Variation
There are five factors that can lead to evolution.
Genetic Variation
• Genetic drift changes allele frequencies due to chance alone.
Genetic Variation
• Gene flow moves alleles from one population to another.
Genetic Variation
• Mutations produce the genetic variation needed for evolution.
Genetic Variation
• Sexual selection selects for traits that improve mating success.
Genetic Variation
• Natural selection selects for traits advantageous for survival.
Genetic Variation
• In nature, populations evolve.
– expected in all populations most of the time
– respond to changing environments
Genetic Variation
Section OutlineThe Process of Speciation
A. Isolating Mechanisms
1. Behavioral Isolation
2. Geographic Isolation
3. Temporal Isolation
B. Testing Natural Selection in Nature
1. Variation
2. Natural Selection
3. Rapid Evolution
C. Speciation of Darwin’s Finches
1. Founders Arrive
2. Separation of Populations
3. Changes in the Gene Pool
4. Reproductive Isolation
5. Ecological Competition
6. Continued Evolution
Section 16-3
Genetic Variation
Speciation
Formation of a new species
Reproductive Isolation
Separation of a species that does not allow interbreeding
Behavioral Isolation
Reproductive isolation due to differing mating rituals
Geographic Isolation
Reproductive isolation due to physical barriers.
Temporal Isolation
Reproductive isolation caused by differing reproductive timing
Genetic Variation
KEY CONCEPT New species can arise when populations are isolated.
Genetic Variation
A. Speciation
SPECIATION - Formation of new species.• A new species has evolved when enough shifts in the
gene pool results in it becoming reproductively isolated from other populations.
1. Reproductive Isolation – defines a species as a population that no longer interbreed with other populations to produce fertile offspring
Genetic Variation
2. Isolation Mechanisms
Behavioral Isolation – do not mate because of incorrect behavior cues – displays, courting rituals, songs, etc.
4 leopard frog species overlap habitat but have different mating calls
Genetic Variation
2. Isolation Mechanisms
Geographic Isolation –separated by physical barriers – water, mountains, habitat differences, etc.
Squirrels living on opposite sides of the Grand CanyonSquirrels living on opposite sides of the Grand Canyon
Genetic Variation
2. Isolation Mechanisms
Temporal Isolation – no longer reproduce at the same time/same season
Different species of frogs may live in same pond, but reproduce at different times. One in March and one in June.
Genetic Variation
The isolation of populations can lead to speciation.
Populations become isolated when there is no gene flow. – Isolated populations adapt to their own environments.– Genetic differences can add up over generations.
Genetic Variation
Species Formation Begins with Microevolution
Divergence is the accumulation of differences between groups (population, species etc.)
Separate populations of same species may become very different.
Ecological Races occur when separate populations continue to accumulate genetic changes due to the environment.
Genetic Variation
(Ex: Seaside sparrows)
In each environment, local population of species become better adapted to environment.
Genetic change may continue to diverge until the populations can no longer interbreed successfully. A new species has formed.
Genetic Variation
Molecular and genetic evidence support fossil and anatomical evidence.
• Two closely-related organisms will have similar DNA sequences.
Genetic Variation
• Pseudogenes are sequences providing evidence of evolution.– no longer function– carried along with functional DNA– can be clues to a common ancestor
Genetic Variation
• Hox genes indicate a very distant common ancestor.
– control the development of specific structures– found in many organisms
• Protein comparisons, or molecular fingerprinting reveals similarities among cell types of different organisms.
Genetic Variation
• Scientist from any fields contribute to the understanding of evolution.
• The basic principles of evolution are used in many scientific fields.
Evolution unites all fields of biology.
Genetic Variation
Concept MapSection 16-3
results from
which include
produced by produced byproduced by
which result in
which result in
Reproductive Isolation
Isolating mechanisms
Behavioral isolation Temporal isolationGeographic isolation
Behavioral differences Different mating timesPhysical separation
Independentlyevolving populations
Formation ofnew species
Genetic Variation
Checkpoint
1. What is genetic drift?
2. What is gene flow?
3. Define gene frequency?
4. What are the three types of selection on polygenic traits?
5. Which type of selection favors two different phenotypes?
6. What is genetic equilibrium?
69ANY QUESTIONS?
Genetic Variation
II. Macroevolution
broader pattern of evolutionary change over time (like new species).
• what we see when we look at the over-arching history of life: change, stability, extinction
• Asks the big questions:– Can we trace the history of life on earth?– How are living things related?– What happened to the dinosaurs?
13.1 Ecologists Study Relationships
I. MicroevolutionChanges in a population’s gene pool
Genetic Variation
Microevolution & Macroevolution
Microevolution – change in alleles and traits in a population over time
can lead to..Macroevolution – broader pattern
of evolutionary change over time (like new species).
earth.
Genetic Variation
2. Microevolution = evolution of genes within a population
• Change in gene frequency of alleles within a population over time.
• Because shifts in gene frequency equals shifts in traits– If advantageous to be brown, then selection for more
brown mice. More brown mice = more b alleles in the population.
Genetic Variation
Macroevolution
Genetic Variation
B. Theories on evolution rates
1. Gradualism (Darwin) – Species change slowly over time branching into new species (fossil transitions)
Genetic Variation
B. Theories on evolution rates
2. Punctuated Equilibrium (Gould & Lewontin) –
Species can undergo rapid “bursts” of evolution (isolation, new niche, etc.)
BOTH CAN OCCUR!
Genetic Variation
Can we see evolution occur?
• Can you think of an example of an organism that evolves “quickly”? One that has evolved during your life time?
Genetic Variation
Bacterial EvolutionWhat allows bacteria to evolve so quickly?
Genetic Variation
Insect Evolution
Genetic Variation
C. Patterns of Evolution
1. Divergent evolution –populations branching into two or more species as they become more dissimilar
Homologous structures & recent common ancestor
Ex: Adaptive radiation – population divides into a series of related species occupying different niches (roles)
Genetic Variation
C. Patterns of Evolution
2. Convergent evolution - unrelated species with similar adaptations due to similar environmental pressures
• Analogous structures
Genetic Variation
3. Coevolution – mutual selection by two or more species in close interaction
Ex: predator/prey; parasites/host
pollinators/plants
C. Patterns of Evolution
Genetic Variation D. Extinction
1. Background extinction – routine loss of species to natural selection
conditions change, competitors or predators superior, etc.
Total loss of all members of a species
Species unable to adapt to environment changes
Ex: dodo bird, passenger pigeon, dinosaurs
Genetic Variation D. Extinction
2. Mass extinction – event in which many species lost in relatively short period
– major changes in ecosystems
– Major loss of biodiversity on planet = less raw material for evolution
– Major loss of useful genes!
Genetic Variation
Evolution not always = better.
Evolutionary sequence is NOT always progress.
Successful evolutionary Successful evolutionary pathways are littered with pathways are littered with dead-end branches, dead-end branches, chance events, and chance events, and unusual survivors.unusual survivors.
Genetic Variation
Checkpoint
1. What are the differences between microevolution and macroevolution?
2. How are speciation and reproductive isolation related?
3. What are three isolation mechanisms?
4. Compare the two rates of evolution.
5. What are the three patterns of evolution?
6. What are the two types of extinction?
86ANY QUESTIONS?