general description - csicw1.iata.csic.es/memoria/pe2010/iata-centro101.pdf · 2009-05-07 · iata...

IATAInstituto de Agroquímica y Tecnología de Alimentos

General descriptionIdentification Data

Name : Instituto de Agroquímica y Tecnología de Alimentos

Address: Apartado 73. 46100-Burjassot (Valencia)

Phones:

963900022 (Switchboard)

963900022-3105 (Address)

96 3900022-3101 (Manager)

Director: Dr. LORENZOZACARIAS GARCIA - [email protected]

Vicedirectors: Dr. ANTONIO MARTINEZ LOPEZ

Manager: ASCENSIO NAVARRO ALARCO - [email protected]

Web: http://www.iata.csic.es/

Govern mode: Instituto de Claustro ampliado

Brief history

Date of creation : 1966-09-25

Who created it : José Ibañez Martín

Who was its first director : Eduardo Primo Yúfera

Goals : Potenciar las investigaciones y la formación científico-tecnológica en Ciencia y Tecnología de

Alimentos en la Comunidad Valenciana

Extended description : The Instituto de Agroquímica and Technología de Alimentos (IATA) (Institute of Agrochemistry

and Food Technology) was founded in 1957 within the Department of Plant Chemistry,dependent on the ?Alonso Barba? Institute of Chemistry which no longer exists, under thePatronage of Juan de la Cierva Scientific and Technical Research. These laboratories werelocated at the School of Chemical Sciences of Valencia University until 1966 at which point they

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mailto:[email protected]

mailto:[email protected]

http://http://www.iata.csic.es/


moved to a new building in Jaime Roig street, Valencia, and adopted its current name Institutode Agroquímica and Technology de Foods. It was the first CSIC research institute in Valencia During the early years of its scientific life, the IATA focused its research on vegetable foodstuffsthat were of economic importance in the Valencian region, fundamentally citrus and rice, and inthe following years its research work became progressively more diversified, moving towardsother lines and products, adapting to the demands of the different agro-food sectors. As a resultof the important and dynamic research activity developed over a number of decades, the IATAbecame a pioneering centre, point of national and international reference for Food Science andTechnology and was, at the same time, the cradle in which other scientific research lines werepromoted, related to agronomy, environment and natural resources that, later on, gave rise toother independent research Institutes in Valencia, like the Instituto de Biologia Molecular yCelular de Plantas (IBMCP) (Institute of Molecular and Cellular Plant Biology) and the Centre deInvestigaciones sobre Desertification (CIDE) (Centre for Desertification Research). It is worthpointing out that for 35 years a post-graduate course in Food Technology Specialization wasimparted at the IATA, giving a Diploma granted by the Ministry of Education and Science, whichwas an important reference point for Food Science Training studies, both in Spain and inLatin-American countries. Likewise, the sixties saw the first edition of the Review ofAgrochemistry and Food Technology, which after 1995 became known as ?Food Science andTechnology International?, edited first of all by Chapman & Hall and currently by SAGEPublications. The review is listed in the Science Citation Index and the Editorial Board resides atthe IATA. In July 1995 the IATA moved to its present premises located in Paterna, 7 Km fromValencia. These installations are part of the University Science Park Parque Científico de laUniversidad de Valencia Estudi General (UVEG), together with another 5 research institutesbelonging to the UVEG or joint UVEG-CSIC are located. Therefore, the IATA is integrated insurroundings housing different research institutes, sharing the entrance and exit and othercommon facilities, like the canteen as well as common diffusion and dissemination projects. It is worth highlighting that in 2003 the company BIOPOLIS S.L. was set up, dedicated toresearch and development of food biotech processes, the CSIC being the main shareholdertogether with other companies in the private sector (Natraceutical, Corporation AlimentariaPeñasanta and Talde). The said company came into being as a result of a FEDER project inwhich numerous IATA researchers participated, and its headquarters are located in the IATAlaboratories and installations. In a year the company Lifesequencing S.L. was set up by BiopolisS.L., a sequencing service company which is also located at the IATA. At the end of the currentyear, both companies will move to new UVEG premises, next to the Scientific Park, destined to?spin-off incubators

Structure

Description : The current structure of the IATA is made up of three Departments and six Research Support

and Service Units. The figure represents the organizational chart of the IATA.

The IATA research is divided into the following departments:? Biotechnology Department ? Food Quality and preservation Department? Food Science Department

List of Research Support and Service Units:

? Administration and general services? Maintenance? Pilot Plant? Computer Science and Statistics? Library and Documentation Service

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? Genomic, proteomic and cell-culture support unit (Service set up in the year 2007)

The IATA is a centre belonging to the Spanish Scientific Research Council (CSIC) with anextended Faculty Board. This situation originated in 1995, when an Agreement was signed withthe UVEG by which different lecturers/professors of this University carrying out their researchwork within the ambit of agro-foods moved to the laboratories located at the IATA, whilemaintaining their teaching commitments at their respective Schools. Thus, coinciding with themove to the new installations in Paterna, 9 teaching staff from the UVEG joined the ScientificCommittee of the IATA and after certain staff leaving and new staff appointments, at presentthere are 7 teaching staff belonging to the IATA, both graduates and Doctors under contractfrom the Department of Bromatology and Preventive Medicine, the Department of Biochemistryand Molecular Biology and the Department of Microbiology.The IATA staff is made up of 56 researchers (8 of whom are UVEG lecturers/professors), 59 staffconnected to research, among civil servants and workers under contract, 52 pre-doctoralresearch students and 52 staff under contract, both technicians and post-docs, which totals 217people with a relatively stable connection to the Centre, in addition to a variable number ofgraduates, engineers temporarily carrying out their graduate projects or short stays.

Infrastructure The IATA has its own facilities with a total surface area of 11.230 m2. New laboratories andoffices are being equipped in the basement, included in the aforementioned total surface area.The construction of a third block of laboratories and offices is also underway, taking up thesame plot, which will have four stories each having a surface area of approximately 2.700 m2.The new installations are forecast to be finished at the beginning of 2011.

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Staff

Male Female TOTAL

Scientific 39 (41%) 57 (59%) 96 (100%)

Support 22 (42%) 31 (58%) 53 (100%)

Management 4 (40%) 6 (60%) 10 (100%)

Maintenance 1 (100%) 0 (0%) 1 (100%)

TOTAL 66 (41%) 94 (59%) 160 (100%)

Scientific personnel by type

Male Female TOTAL

Scientific Research Professor 5 - (71%)% 2 (29%) 7 (100%)

Civil Servant Research Scientist 7 - (54%)% 6 (46%) 13 (100%)

Tenured Scientist 10 - (42%)% 14 (58%) 24 (100%)

Full University Professor 0 - % 0 0

University Professor 0 - (0%)% 4 (100%) 4 (100%)

Other 0 - (0%)% 1 (100%) 1 (100%)

Scientific Ramón y Cajal 2 - (50%)% 2 (50%) 4 (100%)

Hired JAEDOC 2 - (33%)% 4 (67%) 6 (100%)

Other 3 - (75%)% 1 (25%) 4 (100%)

Scientific JAEPREDOC 3 - (25%)% 9 (75%) 12 (100%)

Training Other 7 - (33%)% 14 (67%) 21 (100%)

Scientific personnel 39 - (41%)% 57 (59%) 96 (100%)

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Staff by payer organization

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Funding by type

YEAR : 2003,2004,2005,2006,2007

YEAR : 2003 YEAR : 2004

YEAR : 2005 YEAR : 2006

YEAR : 2007

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Funding by type

2003 2004 2005 2006 2007 TOTAL

CSIC 2 21 69 120 90 302

National Plan 953 1110 804 1586 1440 5893

International 144 346 6 195 29 720

CCAA 376 235 254 35 39 939

Other 0 0 0 0 0 0

Contracts 138 168 164 393 287 1150

Consolider 0 0 0 0 97 97

Cenit 0 0 0 0 0 0

Ciber 0 0 0 0 0 0

Specials Profit 0 0 0 0 0 0

Petri 103 79 0 226 23 431

Large Instalations 0 0 0 0 0 0

Subtotal 103 79 0 226 120 528

TOTAL 1715 1959 1297 2556 2006 9532

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Funding by type/year

Data in (K€) 2003 2004 2005 2006 2007 TOTAL

CSIC 2 21 69 120 90 302National Plan 953 1110 804 1586 1440 5893International 144 346 6 195 29 720

CC.AA. 376 235 254 35 39 939Other 0 0 0 0 0 0

Contracts 138 168 164 393 287 1150Specials 103 79 0 226 120 528

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Publications

Publications by type

Publications by typeType 2003 2004 2005 2006 2007 Total

Article/Book chapter 78 99 113 141 154 585Books 0 0 7 11 7 25

Congress 1 0 0 1 0 2TOTAL 79 99 120 153 161 612

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Article / Book chapters by impact

Article / Book chapters by impactType 2003 2004 2005 2006 2007 TotalHIGH 56 76 60 73 89 354

MEDIUM 15 17 21 27 20 100LOW 6 3 1 14 10 34

Not assigned 1 3 31 27 35 97TOTAL 78 99 113 141 154 585

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Knowledge Transfer

Requested patents

Requested patentsType 2003 2004 2005 2006 2007 Total

Línea de investigacióngeneral del centro

0 0 0 0 0 0

Food quality andproperties

1 0 3 2 4 10

Food biotechnology 3 1 0 5 0 9Food preservation and

safety0 0 0 0 0 0

Functional foods andingredients

0 0 0 1 5 6

TOTAL 4 1 3 8 9 25

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Licensed patents

Licensed patentsType 2003 2004 2005 2006 2007 Total

TOTAL 0 0 0 0 0 0

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Spin-Offs

Spin-OffsType 2003 2004 2005 2006 2007 Total

Línea de investigacióngeneral del centro

0 0 0 0 0 0

Food quality andproperties

0 0 0 0 0 0

Food biotechnology 0 0 1 0 0 1Food preservation and

safety0 1 0 0 0 1

Functional foods andingredients

1 0 0 0 0 1

TOTAL 1 1 1 0 0 3

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Training by type

Training by typeType 2003 2004 2005 2006 2007 Total

Theses 8 5 9 10 9 41Courses (hours) 0 0 1340 1735 1176 4251

TOTAL 8 5 1349 1745 1185 4292

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Science divulgation activities

Science divulgation activities Type 2003 2004 2005 2006 2007 Total

Events 0 0 0 0 0 0Materials 0 0 0 0 0 0

TOTAL 0 0 0 0 0 0

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SWOT

Weaknesses

- A general weakness is related to human resources. Even in the last four-year period, animportant effort in the appointment of new scientific staff members has been made, there isstill a need to attract new researchers to implement new scientific projects and also tointroduce new technologies and ideas to the current projects. This situation makes it difficult toapproach new lines of work and to improve the competitiveness of the existing ones. In thatsense, IATA and its researches should offer an open scenario to prospective staff able tointegrate new perspective and approaches to ongoing research programs.

- A serious weakness lies with technical or support personnel. There have been very fewpersonnel appointments in recent years and even in some cases new two-year technicalpersonnel have been appointed, there is still an imbalance among the different labs of the IATA.We have tried, to keep a ratio of at least one technical for two staff researches, but it has notalways been possible, especially after retirement, transfers, or unexpected situations. On theother hand, the average age of this group is very high and relatively homogenous, which willlead to a great number of retirements in a relatively short period of time. We should, therefore,try to replace and increase this section of personnel and to improve their distribution amongthe different groups in order to improve their research potential.

- During the period of this strategic plan (2010-2013) a large number of administrative staff andservices personnel will retire. This situation would seriously weaken the IATA and its activity,and we must try to replace as far as possible the number of retirements and also to implementnew or alternative systems in order to maintain the regular services and activities.

- Certain weaknesses exist in some specific aspects of research lines in which there is stillcompetitive capacity, but if we do not replace early retirements or we do not attract newscientists it may become a weak point at the IATA. This situation may happen in some researchlines, such as sensorial analysis, enzyme biotechnology, chemical food safety, juice technologyand quality.

- Weaknesses are also detected in functional foods and aspects related to nutrition, in which theIATA does not have a relevant competitive position. In recent years important efforts have beenmade and competitive program funding has been obtained. Even many research groups havespin-off activities related to specific aspects of functional foods, some weaknesses still exist,overall related to functional compound analysis, experimentation in vivo and preclinical tests,issues that are receiving our attention.

- A weakness may be envisaged for certain research groups that focus or concentrate theiractivity excessively on very sectorial subjects. Although at the moment they are competitiveand demonstrate indicators of quality, they could be exposed to greater risks on facing possiblefuture events, in such a narrowly focussed work scope. The same issue can be raised for groupsthat repeatedly maintain their activity in very specific topics, where the lack of innovation andoriginality can imply a threat or difficulties for procuring external funding.

- An excessive fragmentation of research groups or groups with few research personnel couldbecome a weakness of the IATA and put at risk procurement of funding for competitive projects,in which greater human resources are required.

- We have recently implemented a new research service to support genomic, proteomic, cellculture and microscopy techniques, with new qualified technical personnel. This service is nowat its early stages, and investments have been made in setting up the service and equipment.This research service should be supported and expanded in order to be fully efficient and toestablish the conditions to cater to the needs of the different research lines in these newtechnologies of global analysis. New high throughput techniques that may be implemented inthe IATA in a near future (such as metabolomic, and applications of mass spectrometry) orother high-cost equipment must be carried out with the back-up of new trained personnel and

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equipment.

- It is difficult to acquire and replace high-cost scientific equipment and the pilot plant, which ishard to finance through competitive projects, since the infrastructure programs are clearlyinsufficient to cover these needs.

- Indirectly, but with effects on the way society envisages research being carried out, we shouldpoint out the absence of a good service for the diffusion of results and the low profile of the OTT(Technology Transfer Service), making it difficult to transfer technology and to gainopportunities in the sector.

- Finally, the lack of flexibility in the management and administration systems put the IATA, likeother centres or institutes of the CSIC, in a position of inferiority compared to national andinternational competitors with more dynamic structures.

Threats

- A threat derived from the aforementioned weaknesses is the need to increase the number ofscientific personnel in specific groups, in which appointments should be made and vacanciesfilled in order to maintain their competitive position.

- The shortage of staff to support research and the failure to replace staff can pose a threat tothe continuance of IATA?s woring activities. If measures are not taken in the course of thefour-year period corresponding to this strategic plan, the situation will become a real threat, inwhich a huge number of retirements will take place. This situation is clearly illustrated by thefact that during the 4-year period of this strategic plan 20 non-scientific staff members are dueto retire.

- A general threat to the Spanish research system of Science and Technology, which is affectingus progressively, concerns the absence of a well-defined career path in research and lack ofincentives. This dissuades new personnel from incorporating, and cuases serious problems inrecruiting well-qualified students for PhD work.

- Changes in legislation and the current perception of genetically modified organisms could be athreat for the research groups in food biotechnology that would jeopardize their strategies ofgenetic manipulation aimed at the production and improvement of food.

- The shortage of public resources allocated to research in agriculture and the food industry is aserious threat. The national plans in agriculture and food are unable to cover all the currentneeds and on occasions they hinder new commitments to less stable or risky topics. Thisproblem is equally relevant to the renewal or acquisition of new scientific equipment.

- The difficulty to access funding of European Union Framework Programme means a generalthreat to several national institutes. The new guidelines of the 7th Programme would suggestbetter competitive conditions for the IATA, as in previous programmes.

- A threat derived from the Spanish managerial structure in agriculture and the food industry isthe scarce involvement of companies, with a small allocation of resources to research. Themajority of companies in this sector are small to medium sized and their possibilities andtendencies towards research, as opposed to other scientific areas, are limited.

- The lack of connection between the technological centres and the research institutesjeopardizes what should be the natural means of technology diffusion and transfer.

- We have not yet envisaged the improvement in our regular activities that the change of theCSIC to Agencia Estatal has had. We still face the same difficulties and bureaucratizedadministrative management in the research carried out.

Strengths

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- Multidisciplinary expertises and capabilities. One of the IATA?s most important strengths isderived from the wide range of disciplines or scientific subjects within the area of Food Scienceand Technology covered in our research programs. The range of abilities and resources in thedifferent scientific disciplines within Food Science allows the institute to undertake R+D+Iprojects from a comprehensive and multidisciplinary approach, to deal with basic aspects or togenerate knowledge, as, for instance, from the perspective of industrial application. At thesame time, this strength makes it special among institutes in the area of Food Science andTechnology belonging to the CSIC, as well as other national centres or university departments,and it is to this, that the IATA owes the prestige it has consolidated over its long scientifictrajectory.

- Application of Biotechnology to food science. The Biotechnology research area, in the way it isaddressed at the IATA, is the only one belonging to the CSIC that works with allmicro-organisms of industrial interest, such as bacteria, yeasts and filamentous fungi and in thebioprocesses in which they take part. Biotechnological approaches to nutritional and qualityaspect of edible vegetables and to post harvest storage are also addressed. Moleculartechniques and biotechnological strategies are also applied in other research projects of theInstitute, like food safety, microbial taxonomy, and protein engineering, among others. Recenttechniques of global analyses or high throughput technologies (genomics and proteomics) arenow being applied to different subject and research project in the IATA.

- The activities in food safety constitute another of the IATA?s strengths. This activity is of specialrelevance currently and at the IATA there is experience and capacity in most of the relevantissues and industrial and consumer concerns of food safety (microbiological risk assessment,predictive microbiology, rapid analytical methods of detection and speciation of heavy metals,molecular methods to identify and characterize alterative and pathogenic micro-organisms andthe development of immunological methods to detect chemical and biological polluting agents).This diversity of experimental approaches and applications to guarantee food safety, also,constitutes another distinguishing singularity of the IATA within the national context, becausethere are no other institutes with this potential and complementariness of resources in thematter of food safety.

- Other scientific strengths are derived from the research lines devoted to important foodproducts, as those derived from cereals, meat products, juice processes and quality andpost-harvest of fruits. These groups, specifically the first two, have long tradition and nationalrecognition, and are pioneering at the IATA and CSIC. The research line in cereals andderivatives is unique in the CSIC and one of the few national groups working on this topic, andcurrently it has an outstanding presence in international institutions. The group working in meatscience also has a long tradition in the IATA and its activity in cured meat products has turned itinto a point of reference among the CSIC centres and also at a national level, as demonstratedby its integration into the Meat CECOC as a founding member. The post-harvest groupconcentrates on citrus fruits and has a strong potential on combining physiological andbiotechnological aspects on the post-harvest quality, conservation and pathology, whichdistinguishes it at a national and international level. Finally, the research being carried out intojuice characterization is strategic in the Comunidad Valenciana and fills an important gap at anational level. The fact that the IATA is able to house groups of these characteristics, workingon important products for the Valencia and national agro-food sector, confers a very significantstrength that is not to be found in other national centres.

- Packaging technologies and application of novel nanotechnologies to food science are alsostrengths of the IATA. The IATA already had long-standiing tradition in the past in foodprocessing and conservation; we developed strong research lines in food packaging andpackaging technologies, and more recently in the application of new nanotechnology derivedprocesses and materials for food science and food packaging. These disciplines are unique anddistinctive at the IATA as compared with other Food Science Institutes belonging to the CSIC.

- Having the ability to integrate sensorial analysis and analysis of food properties, together withthe sampling-room at the IATA, confer a distinguishing singularity. It is important to emphasizethat the availability of this installation and the experience of the consumer?s evaluation andacceptance of foods, confer to the IATA capacities that are still essential in new food

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technology, since we are able to evaluate the sensorial quality and the acceptance of the newfoods that are to be developed in the future.

- Pilot Plant. Some of the aforementioned strengths can be developed adequately given theavailability of facilities and multipurpose pilot plants (meats, cereals, post-harvest, emergingpreservation technologies) and with the potential for future expansion and improvement. Inaddition, this potential allows the Institute to maintain good interaction relationships withindustries pertaining to different agro-food sectors and to undertake technological supportprojects and joint contracts of cooperation.

- A strength derived from the external relations of the IATA is the link with the two mainUniversities located in Valencia (UVEG and UPV). Researches form the IATA are directly involvedin university teaching, in both under- and graduated courses, affording the possibility ofattracting young researchers, besides offering quality teaching. The existence of a unitassociated with the UPV allows the IATA to approach joint collaboration projects in amultidisciplinary way, since the lines of work preferred by the researchers in the two institutionscan be complemented.

- IATA has long tradition of industrial cooperation and maintains strong links with numerouscompanies in their respective research sectors, a fact which allows, besides collaboration intechnological development, to have a clear vision of the needs in the company setting.

- The geographic location of the IATA in important productive agricultural and industrialsurroundings confers strategic advantages affording the possibility to get to know and becomeinvolved in current problems of the agro-industrial sector.

- The new laboratories and offices that are being constructed, and the modifications in the pilotplant, are going to improve our work capacity and available space for new opportunities orresearchers

Opportunities

- Changes in the legislations and concerns related to the effects of foods in human nutrition andhealth, which can imply a change with respect to traditional lines of food research, can providestrategic opportunities for different research lines developed at the IATA in some of thesesectors.

- Growing public interest and concern in food safety, may help the research lines working at theIATA to adapt to the new expectations and needs demanded by the industrial sectors andsociety.

- National strategic programs for nutrition and prevention of obesity and the demand for newfoods with functional properties, offer opportunities for the research lines at the IATA orientedtowards these activities. These would include, mentioning some of the most significantexamples, the studies of the properties and characterization of the effects of functional foods orsome of their components, healthier foods, pre and pro-biotics. An example of the positionadvantageous IATA holds to make the best of these opportunities concern the funding ofseveral research projects on functional foods. Complementary to this, the interest in promotingthe consumption of fresh fruit and vegetables implies a greater support to the research lines inthis context, in which the IATA should explore new opportunities.

- From an environmental perspective or that of "white" technologies, opportunities can arisewhere IATA groups, with their experience, are in a good position to help resolve problems. Theycould achieve this via non-polluting technologies, use and revaluation of by-products in theagro-food industry, non-polluting strategies to control pathogenic agents, among others.

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- Opportunities are derived from IATA?s relationships with other researchers and academicinstitutions throughout the Unidades Asociadas, which allow interdisciplinary networks incommon projects and afford the possibility of using and exchanging equipment and otherfacilities

- Relationships with the two main Valencian Universities (UPV and UVEG) and the involvement inteaching may facilitate the recruitment of new post-graduated students. Furthermore,opportunities for academic positions (part-time) for researches and postdocs can be alsoderived.

- IATA may also have opportunities derived from the external scientific environment currentlygrowing in Valencia. There are many research Institutes and Hospitals (Principe Felipe, IVIA,AINIA, Hospital La Fe, among others) devoted to different scientific fields that can provide newopportunities of collaboration either in scientific projects or by implementing new technologiesthat are unavailable at the IATA.

- The involvement and responsibilities of different IATA members in national and internationalscientific organizations and commitees may generate strategic opportunities to beimplemented in new project programmes or many other activities.

- The multidisciplinary character of research carried out at the IATA can offer different strategicopportunities in the face of external situations, like those that demand the involvement ofspecialized groups to undertake a possible emergency or problem, of interest for the central orautonomic administration. Two examples of this were the involvement of a group from the IATAin the Aznarcollar crisis and IATA?s involvement in the technological Agrofood platform of the?Conselleria d?Agricultura, pesca i Alimentació de la Generalitat Valenciana?.

- Collaboration activities between different research groups can generate strategic opportunitiesin approaching lines of work that are of present interest, like the application of biotechnology toimproving aspects or specific components in the food quality or in pathogen control systems,for example. In this repect, IATA is well positioned to participate and collaborate in researchinitiatives with other scientific teams in Valencia or Spain addressing food-related issues inmany research projects and programmes that other teams cannot take on.

- An opportunity derived from the IATA spin-off, Biopolis, and its present location, is thepossibility of increasing and promoting company relations, thereby acting as a vehicle to buildrelationships with companies from the sector of applied science developed at the IATA.

RA (Relational Analysis)

Competitor groups

- Chemical Analysis Research Center

- Institute: Chemical Analysis Research Center - Institution: National Institute for Agro-Environmental Sciences - Address : Kannondai 3-1-3, Tsukuba, Ibaraki 305-8604, Japan - Web: http://ss.niaes.affrc.go.jp/chemiana/index_e.htm - 10 Recent articles:

Application of a commercial immunoassay to the direct determination of insecticideimidacloprid in fruit juicesWatanabe, E; Baba, K; Eun, H, et al.FOOD CHEMISTRY Volume: 102 Issue: 3 Pages: 745-750 Published: 2007

Immunoassay for iprodione: Key estimation for residue analysis and method validationwith chromatographic technique

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Watanabe, E; Miyake, SANALYTICA CHIMICA ACTA Volume: 583 Issue: 2 Pages: 370-376 Published: FEB 5 2007

Immunoassay for acetamiprid detection: application to residue analysis andcomparison with liquid chromatographyWatanabe, E; Miyake, S; Baba, K, et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY Volume: 386 Issue: 5 Pages: 1441-1448NOV 2006

Reliable enzyme immunoassay detection for chlorothalonil: Fundamental evaluation forresidue analysis and validation with gas chromatographyWatanabe, E; Miyake, S; Ito, S, et al.JOURNAL OF CHROMATOGRAPHY A Volume: 1129 Issue: 2 Pages: 273-282 Published:OCT 6 2006

Evaluation of performance of a commercial monoclonal antibody-based fenitrothionimmunoassay and application to residual analysis in fruit samplesWatanabe, E; Baba, K; Eun, H, et al.JOURNAL OF FOOD PROTECTION Volume: 69 Issue: 1 Pages: 191-198 Published: JAN2006

- Key Lab of Monitoring and Management of Plant Diseases and Pests

- Institute: Key Lab of Monitoring and Management of Plant Diseases and Pests - Institution: Nanjing Agricultural University - Address : Nanjing 210095, China - Web: http://english.njau.edu.cn/default.php - 10 Recent articles:

Effect of hapten structures on specific and sensitive enzyme-linked immunosorbentassays for N-methylcarbamate insecticide metolcarb.Zhang, Qi; Wu, Yunru; Wang, Limin, et al.Anal Chim Acta Volume: 625 Issue: 1 Pages: 87-94 Published: 2008 Sep 5

Construction, production, and characterization of recombinant scFv antibodies againstmethamidophos expressed in Pichia pastoris Li, TJ; Cheng, JR; Hu, BS, et al.WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY Volume: 24 Issue: 6 Pages:867-874 2008

Preparation of specific monoclonal antibodies (MAbs) against heavy metals: MAbs thatrecognize chelated cadmium ionsZhu, XX; Xu, L; Lou, Y, et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 55 Issue: 19 Pages:7648-7653 SEP 19 2007

Hapten heterology for a specific and sensitive indirect enzyme-linked immunosorbentassay for organophosphorus insecticide fenthionZhang, Q; Wang, LB; Ahn, KC, et al.ANALYTICA CHIMICA ACTA Volume: 596 Issue: 2 Pages: 303-311 JUL 23 2007

Production of recombinant ScFv antibodies against methamidophos from aphage-display library of a hyperimmunized mouse

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Li, TJ; Zhang, Q; Liu, Y, et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 54 Issue: 24 Pages:9085-9091 Published: NOV 29 2006

- Department of Food Science

- Institute: Department of Food Science - Institution: University of Foggia - Address : University of Foggia, Via Napoli, 25-71100-Foggia, Italy. - Web: http://www.unifg.it - 10 Recent articles:

Sinigaglia, M; Bevilacqua, A; Corbo, MR, Pati, S, del Nobile, MA : Use of activecompounds for prolonging the shelf life of mozzarella cheese. International DairyJournal 18/6, 624-630, 2008

Nobile, M. A. del; Conte, A.; Incoronato, A. L., Panza, O : Antimicrobial efficacy andrelease kinetics of thymol from zein films. Journal of Food Engineering 89/ 1, 57-63,2008

Mastromatteo, M; Chillo, S; Buonocore, GG, Massaro, A, Conte, A, del Nobile, MA:Effects of spelt and wheat bran on the performances of wheat gluten films.Journal of Food Engineering 88/2, 202-212, 2008

Nobile, M. A. del; Conte, A.; Cannarsi, M., Sinigaglia, M: Use of biodegradable films forprolonging the shelf life of minimally processed lettuce. Journal of Food Engineering85/3, 317-325, 2008

Conte, A; Buonocore, GG; Sinigaglia, M, M, Lopez, LC, Favia, P, d' Agostino, R, delNobile, MA: Antimicrobial activity of immobilized lysozyme on plasma-treatedpolyethylene films. Journal of Food Protection 71/1,119-125, 2008

- Department of Biotechnology & Food Engineering

- Institute: Department of Biotechnology & Food Engineering - Institution: Technion-Israel Institute of Technology - Address : Technion-Israel Institute of Technology, Haifa 32000, Israel. - Web: http://www.technion.ac.il - 10 Recent articles:

Suppakul, P, Sonneveld, K, Bigger, SW, Miltz, J: Efficacy of polyethylene-basedantimicrobial films containing principal constituents of basil. Food Science andTechnology 41/5, 779-788, 2008

Miltz, J, Bigger, SW, Sonneveld, C, Suppakul, P. Antimicrobial packaging material.Patent Number(s): WO2006000032-A1

Miltz, J, Rydlo, T, Mor, A, Polyakov, V: Potency evaluation of a dermaseptin S4derivative for antimicrobial food packaging applications, Packaging Technology andScience, 19/6, 345-354, 2006

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Yam, KL; Takhistov, PT; Miltz, J: Intelligent packaging: Concepts and applications.Journal of Food Science 70/1, R1-R10, 2005

Miltz, J; Perry, M: Evaluation of the performance of iron-based oxygen scavengers, withcomments on their optimal applications, Packaging Technology and Science, 18/1,21-27, 2005

- Instituto: Dept Chem Engn, Chem Biochem Proc Technol & Control

- Institute: Instituto: Dept Chem Engn, Chem Biochem Proc Technol & Control - Institution: Katholieke Univ Leuven - Address : W Croylaan 46, B-3001 Louvain, Belgium - Web: http://cit.kuleuven.be/en/index.php - 10 Recent articles:

Antwi, M., Theys, T. E., Bernaerts, K., Van Impe, J. F., & Geeraerd, A. H. (2008).Validation of a model for growth of Lactococcus lactis and Listeria innocua in astructured gel system: Effect of monopotassium phosphate. International Journal ofFood Microbiology, 125 (3), 320-329.

Vermeulen, A., Dang, T. D. T., Geeraerd, A. H., Bernaerts, K., Debevere, J., Van Impe, J.,& Devlieghere, F. (2008). Modelling the unexpected effect of acetic and lactic acid incombination with pH and a(w) on the growth/no growth interface ofZygosaccharomyces bailii. International Journal of Food Microbiology, 124 (1), 79-90.

Antwi, A., Bernaerts, K., Van Impe, J. F., & Geeraerd, A. H. (2007). Modelling thecombined effects of structured food model system and lactic acid on Listeria innocuaand Lactococcus lactis growth in mono- and coculture. International Journal of FoodMicrobiology, 120 (1-2), 71-84.

Garcia-Gonzalez, L., Geeraerd, A. H., Spilimbergo, S., Elst, K., Van Ginneken, L.,Debevere, J., Van Impe, J. F., & Devlieghere, F. (2007). High pressure carbon dioxideinactivation of microorganisms in foods: The past, the present and the future.International Journal of Food Microbiology, 117 (1), 1-28.

Gysemans, K. P. M., Bernaerts, K., Vermeulen, A., Geeraerd, A. H., Debevere, J.,Devlieghere, F., & Van Impe, J. F. (2007). Exploring the performance of logisticregression model types on growth/no growth data of Listeria monocytogenes.International Journal of Food Microbiology, 114 (3), 316-331.

- Integration of Sensory Perception Group

- Institute: Integration of Sensory Perception Group - Institution: TI Food and Nutrition - Address : Nieuwe Kanaal 9ª, 6709 PA Wageningen, The Netherlands - Web: http://www.tifn.nl/webdb/ - 10 Recent articles:

Bult, J.H.F., De Wijk, R.A., Hummel, T. (2007) Investigations on multimodal sensoryintegration: Texture, taste, ortho- and retronasal stimuli in concert. NeuroscienceLetters. 411, 6 ? 10.

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De Wijk, R.A., Dijksterhuis, G., Vereijken, P., Prinz, J.F., Weenen, H. (2007) PROPsensitivity reflects sensory discrimination between custard desserts. Food Quality andPreference 18, 597 - 604.

De Wijk, R.A., Janssen, A.M., Terpstra, M.E.J., Prinz, J.F. (2005) Perceived creaminess ofsemi-solid foods. Trends in Food Science & Technology, 17, 412 - 422.

De Wijk, R.A., Prinz, J.F. (2007) Fatty versus creamy sensations for custard desserts,white sauces, and mayonnaises . Food Quality and Preference, 18, 641 ? 650

De Wijk, R.A., Prinz, J.F., Janssen, A.M. (2006) Explaining perceived oral texture ofstarch-based custard desserts from standard and novel instrumental tests. FoodHydrocolloids, 20, 24 ? 34

- Dublin Institute of Technology

- Institute: Dublin Institute of Technology - Institution: School of Food Science and Environmental Health - Address : Cathal Brugha St., Dublin 1, Ireland - Web: http://fseh.dit.ie/index.html - 10 Recent articles:

Tiwari, B. K., Muthukumarappan, K., O'Donnell, C. P., & Cullen, P. J. (2008). Effects ofsonication on the kinetics of orange juice quality parameters. Journal of Agricultural andFood Chemistry, 56, 2423-2428.

Tiwari, B. K., Muthukumarappan, K., Donnell, C. P. O., & Cullen, P. J. (2008). Modellingcolour degradation of orange juice by ozone treatment using response surfacemethodology. Journal of Food Engineering, 88, 553-560.

Tiwari, B. K., Muthukumarappan, K., O'Donnell, C. P., & Cullen, P. J. (2008). Kinetics offreshly squeezed orange juice quality changes during ozone processing. J Agric FoodChem, 56, 6416-6422.

Tiwari, B. K., Muthukumarappan, K., O'Donnell, C. P., & Cullen, P. J. (2008). Colourdegradation and quality parameters of sonicated orange juice using response surfacemethodology. LWT - Food Science and Technology, 41, 1876-1883.

Tiwari, C.P. O'Donnell, A. Patras and P.J. Cullen (2008). Anthocyanin and ascorbic aciddegradation in sonicated strawberry juice. Journal of Agricultural and Food Chemistry(In press).

- Department of Food Science, Food Technology and Nutrition

- Institute: Department of Food Science, Food Technology and Nutrition - Institution: National University of Ireland - Address : Cork, Ireland - Web: http://www.ucc.ie/ - 10 Recent articles:

Renzetti, S., Dal Bello, F., Arendt, E.K.

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Microstructure, fundamental rheology and baking characteristics of batters and breadsfrom different gluten-free flours treated with a microbial transglutaminase. (2008)Journal of Cereal Science, 48 (1), pp. 33-45.

Arendt, E.K., Renzetti, S., Moore, M.M. Novel approaches in the design of gluten-free cereal products. (2008) Food Science andTechnology, 22 (1), pp. 43-46.

Arendt, E.K., Ryan, L.A.M., Dal Bello, F. Impact of sourdough on the texture of bread. (2007) Food Microbiology, 24 (2), pp.165-174.

Moore, M.M., Heinbockel, M., Dockery, P., Ulmer, H.M., Arendt, E.K. Network formation in gluten-free bread with application of transglutaminase. (2006)Cereal Chemistry, 83 (1), pp. 28-36.

Moore, M.M., Schober, T.J., Dockery, P., Arendt, E.K. Textural comparisons of gluten-free and wheat-based doughs, batters, and breads.(2004) Cereal Chemistry, 81 (5), pp. 567-575.

- Faculty of Veterinary Sciences

- Institute: Faculty of Veterinary Sciences - Institution: University of Extremadura - Address : Avd de la Universidad s/n, 10071 Cáceres, Spain - Web: http://www.unex.es/veterinaria - 10 Recent articles:

Andrés,A.I., Cava,R., Martin,D., Ventanas,J. and Ruiz,J. (2005) Lipolysis in dry-curedham: Influence of salt content and processing conditions. Food Chemistry 90, 523-533.

Andrés,A.I., Cava,R., Ventanas,S., Muriel,E. and Ruiz,J. (2007) Effect of salt content andprocessing conditions on volatile compounds formation throughout the ripening ofIberian ham. European Food Research and Technology 225, 677-684.

García-Esteban,M., Ansorena,D., Astiasarán,I., Martin,D. and Ruiz,J. (2004) Comparisonof simultaneous distillation extraction (SDE) and solid-phase microextraction (SPME) forthe analysis of volatile compounds in dry-cured ham. Journal of the Science of Food andAgriculture 84, 1364-1370.

Muriel,E., Andrés,A.I., Petrón,M.J., Antequera,T. and Ruiz,J. (2007) Lipolytic andoxidative changes in Iberian dry-cured loin. Meat Science 75, 325-333.

Pérez-Palacios,T., Ruiz,J., Martin,D., Muriel,E. and Antequera,T. (2008) Comparison ofdifferent methods for total lipid quantification in meat and meat products. FoodChemistry 110, 1025-1029.

- Universitat Rovira i Virgili

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- Institute: Universitat Rovira i Virgili - Institution: Facultad de Enología. Departamento de Bioquímica y Biotecnología - Address : Marcel?lí Domingo, s/n. Campus Sescelades. 43007 Tarragona - Web: http://www.urv.es/ - 10 Recent articles:

Quesada IM, Del Bas JM, Bladé C, Ardèvol A, Blay M, Salvadó MJ, Pujadas G,Fernández-Larrea J, Arola L. Grape seed procyanidins inhibit the expression ofmetallothione in genes in human HepG2 cells. Genes Nutr. 2007 Oct;2(1):105-9.

Montagut G, Fernández-Larrea J, Romero M, Esteve M, Bladé C, Blay M, PujadasG, Salvadó MJ, Arola L, Ardévol A. Differential effects of grape-seed derivedprocyanidins on adipocyte differentiation markers in different in vivo situations. GenesNutr. 2007 Oct;2(1):101-3.

Arola A, Vaqué M, Pujadas G, Ardévol AM, Bladé MC, Blay MT, Fernández-LarreaJB, Salvadó MJ, Arola L. In silico identification of red wine catechin binding sites onhuman and rat serotransferrins. Genes Nutr. 2007 Oct;2(1):99-100.

Del Bas JM, Ricketts ML, Baiges I, Quesada H, Ardevol A, Salvadó MJ, Pujadas G, Blay M,Arola L, Bladé C, Moore DD, Fernandez-Larrea J. Dietary procyanidins lower triglyceridelevels signaling through the nuclear receptor small heterodimer partner. Mol Nutr FoodRes. 2008 Oct;52(10):1172-81.

Terra X, Montagut G, Bustos M, Llopiz N, Ardèvol A, Bladé C, Fernández-Larrea J,Pujadas G, Salvadó J, Arola L, Blay M. Grape-seed procyanidins prevent low-gradeinflammation by modulating cytokine expression in rats fed a high-fat diet. J NutrBiochem. 2008 Jul 3. [Epub ahead of print]

- School of Medicine

- Institute: School of Medicine - Institution: University of Maryland - Address : Baltimore, MD 21201, USA - Web: http://www.umm.edu - 10 Recent articles:

Harris KM, Fasano A, Mann DL. Cutting Edge: IL-1 controls the IL-23 response inducedby gliadin, the etiologic agent in celiac disease. J Immunol. 2008 Oct 1;181(7):4457-60.

Lammers KM, Lu R, Brownley J, Lu B, Gerard C, Thomas K, Rallabhandi P,Shea-Donohue T, Tamiz A, Alkan S, Netzel-Arnett S, Antalis T, Vogel SN, Fasano A.Gliadin induces an increase in intestinal permeability and zonulin release by binding tothe chemokine receptor CXCR3.Gastroenterology. 2008 Jul;135(1):194-204.e3.

Paterson BM, Lammers KM, Arrieta MC, Fasano A, Meddings JB. The safety, tolerance,pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliacdisease subjects: a proof of concept study. Aliment Pharmacol Ther. 2007 Sep1;26(5):757-66.

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Catassi C, Fabiani E, Iacono G, D'Agate C, Francavilla R, Biagi F, Volta U, Accomando S,Picarelli A, De Vitis I, Pianelli G, Gesuita R, Carle F, Mandolesi A, Bearzi I, Fasano A. Aprospective, double-blind, placebo-controlled trial to establish a safe gluten thresholdfor patients with celiac disease. Am J Clin Nutr. 2007 Jan;85(1):160-6.

Branski D, Fasano A, Troncone R. Latest developments in the pathogenesis andtreatment of celiac disease.J Pediatr. 2006 Sep;149(3):295-300. Review. No abstractavailable.

Colaborator groups

- Department of Biomolecular Sensing & Diagnostics

- Institute: Department of Biomolecular Sensing & Diagnostics - Institution: Wageningen University - Address : Bornsesteeg, 59 6708PD, building 118 Wageningen, the Netherlands - Web: http://www.afsg.wur.nl - 10 Recent articles:

Assembly of bionanostructures onto beta-cyclodextrin molecular printboards forantibody recognition and lymphocyte cell counting Ludden, MJW; Li, X; Greve, J, et al.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 130 Issue: 22 Pages:6964-6973 2008

Development of a novel and automated fluorescent immunoassay for the analysis ofbeta-lactam antibioticsBenito-Pena, E; Moreno-Bondi, MC; Orellana, G, et al.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 53 Issue: 17 Pages:6635-6642 AUG 24 2005

Single biosensor immunoassay for the detection of five aminoglycosides inreconstituted skimmed milk Haasnoot, W; Cazemier, G; Koets, M, et al.Conference Information: 4th International Symposium on Hormone and Veterinary DrugResidue Analysis, Date: JUN 04-07, 2002 ANTWERP BELGIUM ANALYTICA CHIMICA ACTA Volume: 488 Issue: 1 Pages: 53-60 2003

Neamin as an immunogen for the development of a generic ELISA detectinggentamicin, kanamycin, and neomycin in milk Loomans, EEMG; Van Wiltenburg, J; Koets, M, et al.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 51 Issue: 3 Pages:587-593 JAN 29 2003

The unfolding/denaturation of immunogammaglobulin of isotype 2b and its F-ab andF-c fragmentsVermeer, AWP; Norde, W; van Amerongen, ABIOPHYSICAL JOURNAL Volume: 79 Issue: 4 Pages: 2150-2154 OCT 2000

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- Instituto Tecnológico del Embalaje, Transporte y Logística

- Institute: Instituto Tecnológico del Embalaje, Transporte y Logística - Institution: Instituto Tecnológico del Embalaje, Transporte y Logística - Address : Parque Tecnológico, c/Albert Einstein 1, 46980 Paterna (Valencia) - Web: http://www.itene.com - 10 Recent articles:

M.Gallur, J.Alonso, M.Jordà, C. Fernández, M. Lara, and S.Aucejo: Approved clay ?biopolymer nanocomposites for food contact applications. International Association ofPackaging Research Institutes (IAPRI) Conference, 2008, June 8-12, Bangkok,Thailandia.

Salas J., Alonso J.M., Gallur M., Jordá M., Aucejo S.: Processes and properties ofbiodegradable nanocomposite materials. Revista de Plásticos Modernos 95/ nº620),104-110, 2008

M.Gallur, A.Devis, J.Alonso, J.Salas, M.Jordà and S.Aucejo: Processed biopolymers filmsfilled with modified montmorillonite for packaging applications. Polymer ProcessingSociety 24th Annual Meeting, Salerno, June 15 -19th 2008

Herranz Solana N., Lorente Goméz I., Aucejo Romero S.: Intelligent packaging solutions:an innovative packaging concept to improve safety, transparency and qualityassurance of chilled/frozen fish and poultry products. International Association ofPackaging Research Institutes (IAPRI) Symposium, 2007, September 3-5, Windsor,England.

García-Romeu-Martínez M.A., Singh S.P, Cloquell-Ballester V.A, Saha K. Measurementand analysis of vibration levels for truck transport in Spain as a function of payload,suspension and speed. Packaging Technology and Science, 26, 421-429, 2007

- School of Packaging

- Institute: School of Packaging - Institution: Michigan State University - Address : School of Packaging, Michigan State University, East Lansing, MI

48824-1223, USA. - Web: http://www.msu.edu/ - 10 Recent articles:

Almenar, E, Samsudin, H, Auras, R, Harte, B, Rubino, M: Postharvest shelf life extensionof blueberries using a biodegradable package. Food Chemistry 110/1, 120-127, 2008

Almenar, E, Auras, R, Rubino, M, Harte, B: A new technique to prevent the main postharvest diseases in berries during storage: inclusion complexesbeta-cyclodextrin-hexanal. International Journal of Food Microbiology118/2, 164-172,2007

Almenar, E, Auras, R, Wharton, P, Rubino, M, Harte, B: Release of acetaldehyde frombeta-cyclodextrins inhibits postharvest decay fungi in vitro. Journal of Agricultural andFood Chemistry 55/17, 7205-7212, 2007

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Kale, G, Auras, R, Singh, SP: Comparison of the degradability of poly(lactide) packagesin composting and ambient exposure conditions. Packaging Technology and Science20/1, 49-70, 2007

Aithani, D, Lockhart, H, Auras, R, Tanprasert, K: Predicting the strongest peelable sealfor 'easy-open' packaging applications. Journal of Plastic Film & Sheeting 22/4,247-263, 2006

- Inst Food Qual & Food Safety

- Institute: Inst Food Qual & Food Safety - Institution: Univ Vet Med - Address : Bischofsholer Damm 15, D-30173 Hannover, Germany - Web: http://www.tiho-hannover.de/ - 10 Recent articles:

Atanassova, V., Reich, F., & Klein, G. (2008). Microbiological quality of sushi from sushibars and retailers. Journal of Food Protection, 71 (4), 860-864.

Atanassova, V., Apelt, J., Reich, F., & Klein, G. (2008). Microbiological quality of freshlyshot game in Germany. Meat Science , 78 (4), 414-419.

Ferrer, C., Tejedor, W., Klein, G., Rodrigo, D., Rodrigo, M., & Martinez, A. (2006). MonteCarlo Simulation to establish the effect of pH, temperature and heating time on thefinal load of Bacillus stearothermophilus spores. European Food Research andTechnology, 224 (2), 153-157.

Klein, G., Beckmann, L., Vollmer, H. M., & Bartelt, E. (2007). Predominant strains ofthermophilie Campylobacter spp. in a german poultry slaughterhouse. InternationalJournal of Food Microbiology, 117 (3), 324-328.

Nowak, B., von Mueffling, T., Grotheer, J., Klein, G., & Watkinson, B. M. (2007). Energycontent, sensory properties, and microbiological shelf life of German bologna-typesausages produced with citrate or phosphate and with inulin as fat replacer. Journal ofFood Science, 72 (9), S629-S638.

- Institute of Agri-Food and Land Use

- Institute: Institute of Agri-Food and Land Use - Institution: Queen?s University Belfast - Address : Room G110 David Keir Building Stranmillis Road Belfast BT9 5AG - Web: http://www.qub.ac.uk/schools/InstituteofAgri-FoodLandUse/Research/ - 10 Recent articles:

Title: Development of a high-throughput enzyme-linked immunosorbent assay for theroutine detection of the carcinogen acrylamide in food, via rapid derivatisationpre-analysis Author(s): Preston, A; Fodey, T; Elliott, CSource: ANALYTICA CHIMICA ACTA Volume: 608 Pages: 178-185 Published: 2008

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Title: Paralytic shellfish poisoning detection by surface plasmon resonance-basedBiosensors in shellfish matrixes Author(s): Fonfria, ES; Vilarino, N; Campbell, K, et al.Source: ANALYTICAL CHEMISTRY Volume: 79 Issue: 16 Pages: 6303-6311 Published:AUG 15 2007

Title: Development and validation of a lateral flow device for the detection of nicarbazincontamination in poultry feeds Author(s): Campbell, K; Fodey, T; Flint, J, et al.Source: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 55 Issue: 6 Pages:2497-2503 Published: MAR 21 2007

Title: Biosensor detects toxic drugs in food Author(s): Elliott, CSource: TRAC-TRENDS IN ANALYTICAL CHEMISTRY Volume: 25 Issue: 11 Pages: IV-VPublished: DEC 2006

Title: Development and validation of an optical SPR biosensor. Assay for tylosinresidues in honey Author(s): Caldow, M; Stead, SL; Day, J, et al.Source: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 53 Issue: 19Pages: 7367-7370 Published: SEP 21 2005

- School of Biosciences, Faculty of Science

- Institute: School of Biosciences, Faculty of Science - Institution: Nottingham University - Address : Room A29 Food Sciences, Sutton Bonington, LE12 5RD - Web: http://www.nottingham.ac.uk/biosciences/foodsci/ - 10 Recent articles:

Rheology, flavour release and perception of low-fat dairy desserts Gonzalez-Tomas, L; Bayarri, S; Taylor, AJ, Costell, E.International Dairy Jopurnal, 18 ,858-866, 2008.

Modelling sweetness and texture perception in model emulsion systems Hollowood, T; Bayarri, S; Marciani, L, et al.European Food Research and Technology, 227, 537-545, 2008.

Flavour release and perception from model dairy custards Gonzalez-Tomas, L; Bayarri, S; Taylor, AJ, Costell, E.Food Research and Technology Volume: 40 Issue: 4 Pages: 520-528, 2007.

The role of rheological behaviour in flavour perception in model oil/water emulsions.Bayarri S*, Smith T, Hollowood T y Hort J European Food Research and Technology,226, 161-168, 2007.

The role of fat in flavour perception: Effect of partition and viscosity in model emulsions

Bayarri, S; Taylor, AJ; Hort, JJournal of Agricultural and Food Chemistry 54, 8862-8868, 2006.

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- Agroquímica y Tecnología de Alimentos

- Institute: Agroquímica y Tecnología de Alimentos - Institution: Consejo Superior de Investigaciones Científicas - Address : Polígono de la Coma/n, Paterna (Valencia). - Web: http://www.iata.csic.es/ - 10 Recent articles:

Torres, E.F., Bayarri, S., Sampedro, F., Martínez, A., Carbonell, J.V. Improvement of thefresh taste intensity of processed clementine juice by separate pasteurization of itsserum and pulp. Food Science and Technology International, 2008, Vol. 14, in press.

Sentandreu, E, Carbonell, L., Rodrigo, D. Carbonell, J. V. Pulsed Electric Fields VersusThermal Treatment: Equivalent Processes to Obtain Equally Acceptable Citrus Juices.Journal of Food Protection, Vol. 69, No. 9, 2006, 2016-2018.

Sampedro, F., Rivas, A., Rodrigo, D., Martinez, A., & Rodrigo, M. (2006). Effect oftemperature and substrate on PEF inactivation of Lactobacillus plantarum in an orangejuice-milk beverage. European Food Research and Technology: 223 (1) 30-34, 223,30-34.

Sampedro, F., Rivas, A., Rodrigo, D., Martinez, A., & Rodrigo, M. (2006). Effect oftemperature and substrate on PEF inactivation of Lactobacillus plantarum in an orangejuice-milk beverage. European Food Research and Technology, 223, 30-34.

Sampedro, F., Rivas, A., Rodrigo, D., Martinez, A., & Rodrigo, M. (2007). Pulsed electricfields inactivation of Lactobacillus plantarum in an orange juice-milk based beverage:effect of process parameters. Journal of Food Engineering: 80, 931-938

- Institute of Food Engineering for Development

- Institute: Institute of Food Engineering for Development - Institution: Polytechnical University of Valencia - Address : Camino de Vera s/n, 46022 Valencia, Spain - Web: http://www.iad.upv.es - 10 Recent articles:

Blesa, E.; Aliño, M.; Barat, J.M.; Grau, R.; Toldrá, F. & Pagán, M.J. (2008) Microbiology ofdry-cured ham during the post-salting stage as affected by partial replacement of NaClby other salts. Meat Science, 78, 135-142.

Gil, L., Barat, J.M., Garcia-Breijo, E., Ibañez, J., Martínez-Máñez, R., Soto, J., Llobet, E.,Brezmes, J., Aristoy, M.C. & Toldrá, F. (2008) Fish Freshness Analysis Using MetallicPotentiometric Electrodes. Sensors and Actuators B: Chemical, 131, 362-370.

Grau, R., Albarracín, W., Toldrá F., Antequera, T and Barat JM. (2008) Study of saltingand post-salting satges of fresh and thawed hams. Meat Science, 79, 677-682.

Barat, J.M., Gil,L.,García-Breijo, E., Aristoy, MC., Toldrá, F., Martínez-Máñez, R. & Soto, J.(2008) Freshness monitoring of sea bream (Sparus aurata) with a potentiometricsensor. Food Chemistry, 108, 681-688.

Barat, JM., Grau, R., Ibáñez, JB., Pagán, MJ., Flores, M., Toldrá, F. & Fito, P. (2006)

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Accelerated processing of dry-cured ham. Part I. Viability of the use of brinethawing/salting operation. Meat Science, 72, 757-765.

- CONICET - Facultad de Ciencias Agropecuarias

- Institute: CONICET - Facultad de Ciencias Agropecuarias - Institution: Universidad Nacional de Cordoba - Address : CC 509, 5000 Cordoba, Argentina - Web: http://www.unc.edu.ar - 10 Recent articles:

Pérez, G.T., Ribotta, P.D., Steffolani, M.E., León, A.E. Effect of soybean proteins on gluten depolymerization during mixing and resting.(2008) Journal of the Science of Food and Agriculture, 88 (3), pp. 455-463.

Ribotta, P.D., Colombo, A., León, A.E., Cristina Anón, M. Effects of soy protein on physical and rheological properties of wheat starch. (2007)Starch/Staerke, 59 (12), pp. 614-623.

Steffolani, M.E., Pérez, G.T., Ribotta, P.D., León, A.E. Relationship between variety classification and breadmaking quality in argentinewheats. (2007) International Journal of Agricultural Research, 2 (1), pp. 33-42.

Barrera, G.N., Pérez, G.T., Ribotta, P.D., León, A.E. Influence of damaged starch on cookie and bread-making quality. (2007) EuropeanFood Research and Technology, 225 (1), pp. 1-7.

León, A.E., Barrera, G.N., Pérez, G.T., Ribotta, P.D., Rosell, C.M. Effect of damaged starch levels on flour-thermal behaviour and bread staling. (2006)European Food Research and Technology, 224 (2), pp. 187-192.

- Instituto del Frío

- Institute: Instituto del Frío - Institution: CSIC - Address : C/ José Antonio Novaris, 10, 28040 Madrid - Web: www.if.csic.es - 10 Recent articles:

Labayen I, Moreno LA, Ruiz JR, González-Gross M, Wärnberg J, Breidenassel C,OrtegaFB, Marcos A, Bueno M; Avena Study Group. Small birth weight and later bodycomposition and fat distribution in adolescents: the Avena study.Obesity (SilverSpring). 2008 Jul;16(7):1680-6.

Moreno LA, Ochoa MC, Wärnberg J, Marti A, Martínez JA, Marcos A. Treatment of obesityin children and adolescents. How nutrition can work?Int J Pediatr Obes. 2008;3 Suppl1:72-7.

Nova E, Wärnberg J, Gómez-Martínez S, Díaz LE, Romeo J, Marcos A.Immunomodulatory effects of probiotics in different stages of life. Br J Nutr. 2007Oct;98 Suppl 1:S90-5.

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Moreno LA, Mesana MI, González-Gross M, Gil CM, Ortega FB, Fleta J, Wärnberg J, LeónJ, Marcos A, Bueno M. Body fat distribution reference standards in Spanish adolescents:the AVENA Study. Int J Obes (Lond). 2007 Dec;31(12):1798-805.

Nova E, Toro O, Varela P, López-Vidriero I, Morandé G, Marcos A. Effects of a nutritionalintervention with yogurt on lymphocyte subsets and cytokine production capacity inanorexia nervosa patients. Eur J Nutr. 2006 Jun;45(4):225-33.

- Instituto de Microbiología, Dpto. Inmunología

- Institute: Instituto de Microbiología, Dpto. Inmunología - Institution: Czech Academy of Sciences - Address : Vídeňská 1083, 142 20 Prague, Czech Republic. - Web: www.biomed.cas.cz/mbu/en/ - 10 Recent articles:

Sánchez D, Palová-Jelínková L, Felsberg J, Simsová M, Pekáriková A, Pecharová B,Swoboda I, Mothes T, Mulder CJ, Benes Z, Tlaskalová-Hogenová H, Tucková L.Anti-calreticulin immunoglobulin A (IgA) antibodies in refractory coeliac disease.ClinExp Immunol. 2008 Sep;153(3):351-9.

Sotkovský P, Hubálek M, Hernychová L, Novák P, Havranová M, Setinová I, KitanovicováA, Fuchs M, Stulík J, Tucková L. Proteomic analysis of wheat proteins recognized by IgEantibodies of allergic patients. Proteomics. 2008 Apr;8(8):1677-91.

Kverka M, Burianova J, Lodinova-Zadnikova R, Kocourkova I, Cinova J, Tuckova L,Tlaskalova-Hogenova H. Cytokine profiling in human colostrum and milk by proteinarray. Clin Chem. 2007 May;53(5):955-62.

Sánchez D, Tucková L, Burkhard M, Plicka J, Mothes T, Hoffmanová I,Tlaskalová-Hogenová H. Specificity analysis of anti-gliadin mouse monoclonalantibodies used for detection of gliadin in food for gluten-free diet.. J Agric Food Chem.2007 Apr 4;55(7):2627-32.

Cinova J, Palová-Jelínková L, Smythies LE, Cerná M, Pecharová B, Dvorák M, Fruhauf P,Tlaskalová-Hogenová H, Smith PD, Tucková L. Gliadin peptides activate bloodmonocytes from patients with celiac disease. J Clin Immunol. 2007 Mar;27(2):201-9.

Leading groups

- Instituto de Investigaciones Químicas y Ambientales de Barcelona (IIQAB-CSIC)

- Institute: Instituto de Investigaciones Químicas y Ambientales de Barcelona(IIQAB-CSIC)

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- Institution: Consejo Superior de Investigaciones Científicas - Address : C/ Jordi Girona, 18-26. 08034-Barcelona - Web: http://www.iiqab.csic.es/amrg/ - 10 Recent articles:

Title: Simultaneous immunochemical detection of stanozolol and the main humanmetabolite, 3 '-hydroxy-stanozolol, in urine and serum samples Author(s): Salvador, JP; Sanchez-Baeza, F; Marco, MPSource: ANALYTICAL BIOCHEMISTRY Volume: 376 Issue: 2 Pages: 221-228 Published:2008

Title: Preparation of antibodies for the designer steroid tetrahydrogestrinone anddevelopment of an enzyme-linked immunosorbent assay for human urine analysis Author(s): Salvador, JP; Sanchez-Baeza, F; Marco, MPSource: ANALYTICAL CHEMISTRY Volume: 79 Issue: 10 Pages: 3734-3740 Published:MAY 15 2007

Title: Determination of haloanisols in white wine by immunosorbent solid-phaseextraction followed by enzyme-linked immunosorbent assay Author(s): Sanvicens, N; Moore, EJ; Guilbault, GG, et al.Source: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 54 Issue: 24Pages: 9176-9183 Published: NOV 29 2006

Title: Development of an enzyme-linked immunosorbent assay for the determination ofthe linear alkylbenzene sulfonates and long-chain sulfophenyl carboxylates usingantibodies generated by pseudoheterologous immunization Author(s): Ramon-Azcon, J; Galve, R; Sanchez-Baeza, F, et al.Source: ANALYTICAL CHEMISTRY Volume: 78 Issue: 1 Pages: 71-81 Published: JAN 12006

Title: Immunochemical determination of 2,4,6-trichloroanisole as the responsible agentfor the musty odor in foods. 1. Molecular modeling studies for antibody production Author(s): Sanvicens, N; Sanchez-Baeza, F; Marco, MPSource: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 51 Issue: 14Pages: 3924-3931 Published: JUL 2 2003

- Laboratory of Pesticide & Biotechnology

- Institute: Laboratory of Pesticide & Biotechnology - Institution: University of California, Davis - Address : One shields avenue, Davis, California 95616-8584 - Web: http://www.biopestlab.ucdavis.edu/ - 10 Recent articles:

High-throughput automated luminescent magnetic particle-based immunoassay tomonitor human exposure to pyrethroid insecticides Ahn, KC; Lohstroh, P; Gee, SJ, et al.ANALYTICAL CHEMISTRY Volume: 79 Pages: 8883-8890 2007

Polyclonal antibody-based noncompetitive immunoassay for small analytes developedwith short peptide loops isolated from phage libraries Gonzalez-Techera, A; Kim, HJ; Gee, SJ, et al.

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ANALYTICAL CHEMISTRY Volume: 79 Pages: 9191-9196 2007

Development of sensitive immunoassays for the detection of the glucuronide conjugateof 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroidexposure Kim, HJ; Ahn, KC; Ma, SJ, et al.Conference Information: 232nd National Meeting of the American-Chemical-Society,Date: SEP 10-14, 2006 San Francisco CA JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 55 Issue: 10 Pages:3750-3757 2007

Microarray immunoassay for phenoxybenzoic acid using polymer encapsulated Eu :Gd2O3 nanoparticles as fluorescent labels Nichkova, M; Dosev, D; Gee, SJ, et al.ANALYTICAL CHEMISTRY Volume: 77 Issue: 21 Pages: 6864-6873 NOV 1 2005

Hapten and antibody production for a sensitive immunoassay determining a humanurinary metabolite of the pyrethroid insecticide permethrin Ahn, KC; Watanabe, T; Gee, SJ, et al.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Volume: 52 Issue: 15 Pages:4583-4594 JUL 28 2004

- Departamento de Química Analítica. Facultad de Ciencias

- Institute: Departamento de Química Analítica. Facultad de Ciencias - Institution: Universidad de Zaragoza - Address : C/ Pedro Cerbuna, 12, 50009 Zaragoza - Web: http:// www.unizar.es - 10 Recent articles:

Nerin, C, Tovar, L, Salafranca, J. Behaviour of a new antioxidant active film versusoxidizable model compounds. JOURNAL OF FOOD ENGINEERING, 84, 313-320 (2008)

Pezo, D, Salafranca, J, Nerin, C. Determination of the antioxidant capacity of active foodpackagings by in situ gas-phase hydroxyl radical generation and high-performanceliquid chromatography-fluorescence detection. JOURNAL OF CHROMATOGRAPHY A,1178, 126-133 (2008)

Rodriguez, A, Nerin, C, Batlle, R. New cinnamon-based active paper packaging againstRhizopusstolonifer food spoilage. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,56, 6364-69 (2008)

Lopez, P, Batlle, R, Salafranca, J, Nerin, C. Efficiency of whole and skimmed powderedmilk for trapping volatile compounds released from plastic containers inhigh-temperature applications. JOURNAL OF FOOD PROTECTION, 71, 1889-97 (2008)

Lopez, P, Sanchez, C, Batlle, R,Nerin, C. Development of flexible antimicrobial filmsusing essential oils as active agents. JOURNAL OF AGRICULTURAL AND FOODCHEMISTRY, 55, 8814-24 (2007)

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- Agropolymers Engineering and Emerging Technologies

- Institute: Agropolymers Engineering and Emerging Technologies - Institution: Université Montpellier II - Address : Pl E. Bataillon cc 023, 34095 Montpellier cedex 05, France - Web: http://www1.montpellier.inra.fr/umr-iate - 10 Recent articles:

Roca, E, Adeline, D, Guillard, V, Guilbert, S, Gontard, N. Modelling and control ofmoisture transfers in high, intermediate and low a(w) composite food. Food Chemistry,106, 1350-1358, 2008.

Charles, F, Guillaume, C, Gontard, N. Effect of passive and active modified atmospherepackaging on quality changes of fresh endives. Postharvest Biology and Technology 48,22-29, 2008.

Angellier-Coussy, H, Torres-Giner, S, Morel, MH, Gontard, N, Gastaldi, E. Functionalproperties of thermoformed wheat gluten/montmorillonite materials with respect toformulation and processing conditions. JOURNAL OF APPLIED POLYMER SCIENCE, 107,487-496 (2008)

BEN A A, CHALIER P, GONTARD N, PREZIOSI B L. Materials based on (non)woven fibroussupports, useful e.g. in food preservation, coated with a matrix comprisingbiodegradable polymers for controlled release of volatile antimicrobial, agentsincorporated into polymers. Patent FR2900940-A1; WO2007135273-A2;WO2007135273-A3(2007)

Arfa, AB, Chrakabandhu, Y, Preziosi-Belloy, L, Chalier, P, Gontard, N. Coating paperswith soy protein isolates as inclusion matrix of carvacrol. FOOD RESEARCHINTERNATIONAL, 40, 22-32 (2007)

- Eastern Regional Research Center. Food Safety Intervention Technologies

- Institute: Eastern Regional Research Center. Food Safety Intervention Technologies - Institution: United States Department of Agriculture (USDA) - Address : 600 East Mermaid Lane, Wyndmoor, PA 19038, - Web: Web:www.ars.usda.gov/main/main.htm - 10 Recent articles:

Ukuku, D.O., Jin, Z., Zhang H. Q. 2008. Survival, viability loss and injury of Escherichiacoli and Salmonella enteritidis in liquid egg thermally treated using thermal-death-disk.Journal of Food Protection.

Ukuku, D. O., Geveke, D. J., Zhang, H. Q., Cooke, P. H. 2008. Membrane damage andviability loss of Escherichia coli K12 of apple juice treated with radio frequency electricfields. Journal of Food Protection.

Yuk, H. Geveke, D.J., Jin, Z., Zhang, H. Q. 2008. Comparison of thermal inactivationkinetics of E. coli K12 in apple cider using conventional glass tube, aluminumthermal-death-time disks and pilot scale pasteurizer. Journal of Food Protection.

Jin, Z., Zhang, H. Q. 2008. Biodegradable polylactic acid polymer with nisin for use in

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antimicrobial food packaging. Journal of Food Science.

Jin, Z., Liu, Liu, Zhang, H. Q., Hicks, K. 2008. Antimicrobial activity of nisin incorporatedin pectin and polylactic acid composite films against Listeria monocytogenes.International Journal of Food Science and Technology

- TI Food and Nutrition

- Institute: TI Food and Nutrition - Institution: TI Food and Nutrition - Address : Nieuwe kanaal 9A, P.O. Box 557, 6700 An Wageningen, The Netherlands - Web: http://www.tifn.nl/ - 10 Recent articles:

Castro-Prada, E.M., Luyten, H., Lichtendonk, W., Hamer, R.J. y Van Vliet, T. ?Animproved instrumental characterization of mechanical and acoustic properties of crispycellular solid food?. Journal of Texture Studies 38, 698 - 724(2007).

Dijksterhuis, G., Luyten, H., De Wijk, R.A. y Mojet, J. ?A new sensory vocabulary for crispand crunchy model foods?. Food Quality and Preference 18, 37 - 50(2007).

Sanz, T., Primo-Martin, C. y Van Vliet,T. ?Characterization of crispness of French fries byfracture and acoustic measurements, effect of pre-frying and final frying times?. FoodResearch International 40, 63 ? 70 (2007).

Luyten, H. y Van Vliet, T. ?Acoustic emission, fracture behaviour and morphology of drycrispy foods, a discussion article?. Journal of Texture Studies 37, 221 ? 240 (2006).

Luyten, H., Plijter, J.J. y Van Vliet, T. ?Crispy / crunchy crusts of cellular solid foods: Aliterature review with discussion?. Journal of Texture Studies 35, 445 ? 492 (2004).

- Department of Food Science & Technology, Physical Properties Group

- Institute: Department of Food Science & Technology, Physical Properties Group - Institution: University of Georgia - Address : Athens, GA 30602 USA - Web: http://www.arches.uga.edu/~lwicker - 10 Recent articles:

Ackerley, J., Corredig, M., & Wicker, L. (2002). Clarification of citrus juice is influencedby specific activity of thermolabile pectinmethylesterase and inactive PME-pectincomplexes. Journal of Food Science, 67, 2529-2533.

Corredig, M. & Wicker, L. (2002). Juice clarification by thermostable fractions of marshgrapefruit pectinmethylesterase. Journal of Food Science, 67, 1668-1671.

Wicker, L., Ackerley, J. L., & Corredig, M. (2002). Clarification of juice by thermolabileValencia pectinmethylesterase is accelerated by cations. Journal of Agricultural andFood Chemistry, 50, 4091-4095.

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Corredig, M. & Wicker, L. (2001). Changes in the molecular weight distribution of threecommercial pectins after valve homogenization. Food Hydrocolloids, 15, 17-23.

Corredig, M., Kerr, W., & Wicker, L. (2001). Particle size distribution of orange juicecloud after addition of sensitized pectin. Journal of Agricultural and Food Chemistry, 49,2523-2526.

- Animal & Natural Resources Institute. Food Technology & Safety Laboratory

- Institute: Animal & Natural Resources Institute. Food Technology & Safety Laboratory

- Institution: Agricultural Research Service (ARS), USDA - Address : 10300 Baltimore Avenue, BARC-East, Bldg. 201, Beltsville, MD 20705-2350,

USA - Web: http://www.ars.usda.gov/ba/foodsafetylab - 10 Recent articles:

Bowker,B.C., Fahrenholz,T.M., Paroczay,E.W., Eastridge,J.S. and Solomon,M.B. (2008)Effect of hydrodynamic pressure processing and aging on the tenderness andmyofibrillar proteins of beef strip loins. Journal of Muscle Foods 19, 74-97.

Bowker,B.C., Fahrenholz,T.M., Paroczay,E.W. and Solomon,M.B. (2008) Effect ofhydrodynamic pressure processing and aging on sarcoplasmic proteins of beef striploins. Journal of Muscle Foods 19, 175-193.

Bowker,B.C., Liu,M.N., Solomon,M.B., Eastridge,J.S., Fahrenholz,T.M. and Vinyard,B.(2007) Effects of hydrodynamic pressure processing and blade tenderization onintramuscular collagen and tenderness-related protein characteristics of top roundsfrom Brahman cattle. Journal of Muscle Foods 18, 35-55.

Sharma,M., Shearer,A.E.H., Hoover,D.G., Liu,M.N., Solomon,M.B. and Kniel,K.E. (2008)Comparison of hydrostatic and hydrodynamic pressure to inactivate foodborne viruses.Innovative Food Science and Emerging Technologies 9, 418-422.

Solomon,M.B., Liu,M.N., Patel,J., Paroczay,E., Eastridge,J. and Coleman,S.W. (2008)Tenderness improvement in fresh or frozen/thawed beef steaks treated withhydrodynamic pressure processing. Journal of Muscle Foods 19, 98-109

- VTT Biotechnology

- Institute: VTT Biotechnology - Institution: VTT Biotechnology - Address : P.O. Box 1500, FIN-02044 VTT, Finland - Web: http://www.vtt.fi/ - 10 Recent articles:

Heiniö, R.-L., Liukkonen, K.-H., Myllymäki, O., Pihlava, J.-M., Adlercreutz, H., Heinonen,S.-M., Poutanen, K. Quantities of phenolic compounds and their impacts on the perceived flavour attributes

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of rye grain. (2008) Journal of Cereal Science, 47 (3), pp. 566-575.

Katina, K., Arendt, E., Liukkonen, K.-H., Autio, K., Flander, L., Poutanen, K. Potential of sourdough for healthier cereal products. (2005) Trends in Food Science andTechnology, 16 (1-3), pp. 104-112.

Salmenkallio-Marttila, M., Heiniö, R.-L., Myllymäki, O., Lille, M., Autio, K., Poutanen, K. Relating microstructure, sensory and instrumental texture of processed oat. (2004)Agricultural and Food Science, 13 (1-2), pp. 124-137.

Juntunen, K.S., Laaksonen, D.E., Autio, K., Niskanen, L.K., Holst, J.J., Savolainen, K.E.,Liukkonen, K.-H., Poutanen, K.S., Mykkänen, H.M. Structural differences between rye and wheat breads but not total fiber content mayexplain the lower postprandial insulin response to rye bread. (2003) American Journalof Clinical Nutrition, 78 (5), pp. 957-964.

Karppinen, S., Myllymäki, O., Forssell, P., Poutanen, K. Fructan content of rye and rye products. (2003) Cereal Chemistry, 80 (2), pp. 168-171.

- Department of Chemical and Biological Engineering

- Institute: Department of Chemical and Biological Engineering - Institution: Chalmers University of Technology. - Address : SE-412 96 Gothenburg, Sweden - Web: http://www.chalmers.se/en/sections/research/professors/jens-b-nielsen-systems - 10 Recent articles:

Andersen MR, Nielsen J. 2008. Current status of systems biology in Aspergilli. FungalGenet Biol. in press

Vongsangnak W, Olsen P, Hansen K, Krogsgaard S, Nielsen J. 2008. Improvedannotation through genome-scale metabolic modeling of Aspergillus oryzae. BMCGenomics. 9: 245.

Andersen MR, Vongsangnak W, Panagiotou G, Salazar MP, Lehmann L, Nielsen J. 2008.A trispecies Aspergillus microarray: comparative transcriptomics of three Aspergillusspecies. Proc Natl Acad Sci U S A. 105(11): 4387-92.

Asadollahi MA, Maury J, Møller K, Nielsen KF, Schalk M, Clark A, Nielsen J. 2008Production of plant sesquiterpenes in Saccharomyces cerevisiae: effect of ERG9repression on sesquiterpene biosynthesis. Biotechnol Bioeng. 99(3): 666-77.

Nielsen ML, Albertsen L, Lettier G, Nielsen JB, Mortensen UH. 2006. Efficient PCR-basedgene targeting with a recyclable marker for Aspergillus nidulans. Fungal Genet Biol.43(1): 54-64.

- VTT Technical Research Centre of Finland

- Institute: VTT Technical Research Centre of Finland - Institution: VTT Technical Research Centre of Finland

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- Address : P0 Box 1500, FN 02044 VTT Espoo, Finland - Web: http://www.biomatnet.org/secure/Contacts/C1108637.htm - 10 Recent articles:

Salusjärvi L, Kankainen M, Soliymani R, Pitkänen JP, Penttilä M, Ruohonen L. 2008.Regulation of xylose metabolism in recombinant Saccharomyces cerevisiae. Microb CellFact. 7: 18.

Koivistoinen OM, Hilditch S, Voutilainen SP, Boer H, Penttilä M, Richard P. 2008.Identification in the yeast Pichia stipitis of the first L-rhamnose-1-dehydrogenase gene.FEBS J. 275(10): 2482-8.

Rintala E, Wiebe MG, Tamminen A, Ruohonen L, Penttilä M. 2008. Transcription ofhexose transporters of Saccharomyces cerevisiae is affected by change in oxygenprovision. BMC Microbiol. 8: 53.

Stricker AR, Trefflinger P, Aro N, Penttilä M, Mach RL. 2008. Role of Ace2 (Activator ofCellulases 2) within the xyn2 transcriptosome of Hypocrea jecorina. Fungal Genet Biol.45(4): 436-45.

Saloheimo A, Rauta J, Stasyk OV, Sibirny AA, Penttilä M, Ruohonen L. 2007. Xylosetransport studies with xylose-utilizing Saccharomyces cerevisiae strains expressingheterologous and homologous permeases. Appl Microbiol Biotechnol. 74(5):1041-52.

- CEBAS

- Institute: CEBAS - Institution: CSIC - Address : POB 164, E-30100 Murcia - Web: www.cebas.csic.es/ - 10 Recent articles:

M. J. Bermúdez-Soto, M. Larrosa, J. García-Cantalejo, J. C. Espín, F. A. Tomás-Barberan,and M. T. García-Conesa. 2007. Transcriptional changes in human Caco-2 colon cancercells following exposure to a recurrent non-toxic dose of polyphenol-rich chokeberryjuice. Genes Nutr. 2007 October; 2(1): 111?113.

Truchado P, Ferreres F, Bortolotti L, Sabatini AG, Tomás-Barberán FA. Nectar Flavonolrhamnosides are floral markers of acacia (Robinia pseudacacia) honey. J Agric FoodChem. 2008 Oct 8;56(19):8815-24.

Possemiers S, Rabot S, Espín JC, Bruneau A, Philippe C, González-Sarrías A, Heyerick A,Tomás-Barberán FA, De Keukeleire D, Verstraete W. Eubacterium limosum activatesisoxanthohumol from hops (Humulus lupulus L.) into the potent phytoestrogen8-prenylnaringenin in vitro and in rat intestine. J Nutr. 2008 Jul;138(7):1310-6.

Azorín-Ortuño M, Urbán C, Cerón JJ, Tecles F, Gil-Izquierdo A, Pallarés FJ,Tomás-Barberán FA, Espín JC. Safety evaluation of an oak-flavored milk powdercontaining ellagitannins upon oral administration in the rat. J Agric Food Chem. 2008Apr 23;56(8):2857-65.

Espín JC, González-Barrio R, Cerdá B, López-Bote C, Rey AI, Tomás-Barberán FA. Iberian

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pig as a model to clarify obscure points in the bioavailability and metabolism ofellagitannins in humans. J Agric Food Chem. 2007 Dec 12;55(25):10476-85.

- Canadian Research and Development Centre for Probiotics, Lawson Health ResearchInstitute

- Institute: Canadian Research and Development Centre for Probiotics, Lawson HealthResearch Institute

- Institution: University of Western Ontario - Address : Ontario N6A 4V2, Canada - Web: www.lhrionhealth.ca - 10 Recent articles:

Reid G. Probiotic Lactobacilli for urogenital health in women. J Clin Gastroenterol. 2008Sep;42 Suppl 3 Pt 2:S234-6.

Cadieux P, Wind A, Sommer P, Schaefer L, Crowley K, Britton RA, Reid G. Evaluation ofreuterin production in urogenital probiotic Lactobacillus reuteri RC-14.Appl EnvironMicrobiol. 2008 Aug;74(15):4645-9.

Reid G. Probiotics to prevent the need for, and augment the use of, antibiotics.Can JInfect Dis Med Microbiol. 2006 Sep;17(5):291-5.

Anukam KC, Osazuwa EO, Osadolor HB, Bruce AW, Reid G. Yogurt containing probioticLactobacillus rhamnosus GR-1 and L. reuteri RC-14 helps resolve moderate diarrheaand increases CD4 count in HIV/AIDS patients. J Clin Gastroenterol. 2008Mar;42(3):239-43.

Reid G. How science will help shape future clinical applications of probiotics. Clin InfectDis. 2008 Feb 1;46 Suppl 2:S62-6; discussion S144-51.

Selective Advantages

Availability of general and multi-sector pilot-plant installations able to cater to the needs andtechnological requirements in a number of topics within Food Science and Technology in theComunidad Valenciana and at a national level, with the possibility of providing services to researchand the industrial sector.

The IATA has a research area working in Food Biotechnology that encompasses and coordinatesresearch groups in different topics within Food Science and Technology (the main micro-organisms infood processes, as well as fruit and vegetables) that are not dealt with by any other centre in this

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area belonging to the CSIC.

Specialized and competitive groups in disciplines that are not present in any other CSIC centresworking in the area of foods (cereals, meat, juices, packaging, nanotechnology applications,chemical contamination, immunodetection, etc.).

High potential and experience in different disciplines within food safety, including microbiologicaland chemical and in food preservation and processing technologies.

Strong academic participation of the main Universities in the area (UVEG and UPV) and importantinvolvement in national and international organizations of Food Science and Technology andresearch management.

Critical Analysis of Research Lines

- Línea de Investigación General del Centro - Status: In regression - Justification:

- Food Quality and Properties - Status: Consolidated - Justification:This research area encompasses four sub-lines with a total de 15 CSIC

researchers, with the common goal of carrying out studies into food properties and quality,nutrition and functionality of important food products of relevance in alimentation, such asderivatives of cereals, meat products and fruit juices. Some of these sub-lines arerepresentative of long-standing scientific projects carried out at the IATA and that havemaintained a competitive track-record over decades. In particular, research into cereals andderived products has been kept up since the origin of IATA and are pioneers in the Spanishcontext, and it is the only group doing this research in the CSIC centres working in the area offoods. The work activities of this group have undergone diversification and adapted to thetrends and needs of the sector, and currently also deal with aspects related to the functionaland nutritional characteristics of new products derived from cereals, maintaining the moreapplied aspects. Research related to meat products also has a wide and long tradition at theIATA and continues to maintain a competitive position within their area of specialization. Thissub-line deals with different aspects of technology and biochemistry of cured meat productsand represents an important sector in our industrial surroundings, therefore it should continuemaintaining its relevant position at the IATA and its collaborations with the industrial andacademic sector. On the other hand, this group is singularly distinctive within the CSIC centresdealing with foods and therefore confers a strategic position to the IATA.The indicators of the level of scientific work are also adequate for the research group dealingwith studies into the physical and sensorial properties of foods. Their relevance at the IATAcomes from their ability to be versatile and apply different methodologies to multiple types offoods, determining their most characteristic properties. Likewise, the availability of asampling-room, adaptable to different needs and their experience in design and sensorialanalysis is an important characteristic of the IATA which it should maintain and promote. Thiswork sub-line is the one that has undergone the greatest growth in scientific staffing in recentyears, compared to other sub-lines, thus is has the resources and is qualified to carry on itsresearch in a competitive way. However, the work in sensorial analysis of foods may bethreatened in the future if new scientists are not incorporated to replace those about to retire,thus enabling the research line to continue to be competitive. Research into quality of fruit juices and derivatives was taken up again at the IATA a few yearsago, as it was a strategic requirement of the Valencian citriculture sector and has focussed oncitrus fruits. Activities of technological nature, together with chemical and functional studies of

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juices are those on which it has focussed its work. This research represents, furthermore, afactor of distinction for the IATA, seeing that there are few national groups working in thissector and it is the only CSIC centre. The activity in this sub-line may be threatened in thefuture by the high average age of the staff and suitable replacement is necessary.

- Food Preservation and Safety - Status: Consolidated - Justification:This research area represents the activity carried out in three sub-lines and

encompasses 12 researchers. The research area encompasses an extended work team thatdeals with aspects related to food packaging and the application of nanotechnology to foods,and two lines connected with food safety, either derived from microbiological risks or risks ofcontamination with toxic chemicals. This range of activities is considered to represent astrength of the IATA, given its importance in the corresponding social and industrial sectors,and because they represent competitive topic areas that differ from the rest of the CSIC centresworking in the food sector. In particular, the packing and packaging technology line is the onlyone with this specialization among the CSIC Institutes and therefore, it should be strategicallypromoted within the IATA, as it enables us to continue to be competitive in areas with hugeindustrial repercussions and implementation. In parallel, a series of applications have beenunder development based on procedures and materials derived from nanotechnology, thatconstitute emerging activities with new applications in diverse fields of the food sector and thathave industrial developments. These two activities encompassed within the sub-line show goodindications of quality and have the capacity to continue to be competitive in the future.The second research area carries out activities that aim to guarantee food safety in thedifferent stages of production, processing, transformation and conservation. On one hand, itdeals with microbiological safety aspects of foods, risk evaluation, and rapid detection systems.This activity is important within the IATA and CSIC scenario, given it offers novel aspects andcombines different technologies and experimental approaches to guarantee microbiologicalsafety and thus certain specific aspects should be consolidated within the IATA.Finally, the research in chemical and residual contamination encompasses two activities withdifferent specific weight. Activities in chemical contaminants containing heavy metals havebeen consolidated over the years in the IATA, and this group is a reference group for the CSICcentres and has international impact. This research area is giving rise to many activities ofdifferent types and the novel research established in recent years, connected withbioavailability, indicates progress and competitiveness. Outstanding is the research begunrecently into developing immunological methods for the detection of pesticides. The trend ofthis topic area has been to grow and has given rise to new experimental technologies at theIATA, such as cell or monoclonal antibody culture, which has been consolidated and extendedto other groups. Although activities in this topic area can still be considered in the emergingphase, it has proven its ability to recruit both economic funding and personnel. Theconsolidation of this research line at the IATA, which is also singular among CSIC centres,requires reinforcing the research staff, which is currently practically unipersonal.

- Functional Foods and Ingredients - Status: Emergent - Justification:This line of work is a minority at the IATA and presents particular characteristics.

Within this area there is only one sub-line comprising four researchers, who dedicate theirefforts and maintain the projects in this topic area alone. However, we must point out that animportant group of researchers at the IATA also carry out work and share activities in thissubject matter either partially or in a complementary way with their main research areas. Thisis clearly illustrated by the fact that the project CONSOLIDER (Fun-C-Food) dealing withfunctional foods, which has recently been funded at a national level, comprises 18 researchers

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at the IATA, dealing with aspects complementary to their research, both at the level of bioactivecompounds of foods, synthesis and characterization, biological capacity and encapsulation, aswell as others related to prebiotics and probiotic microorganismos. Research carried out inother lines of work at the IATA could also fall within the framework of functional foods andingredients, like those working in cured meat products, in fruit juices or in certain derivatives ofcereals. This is, therefore, a work area in which the IATA research as a whole dedicates animportant amount of activity, but in a complementary way and making use of abilities inparallel to the principal areas of work. Just one sub-line within this research area, named ?Biological activity of food components?deals within two different types of activities, on one hand those related to probiotics andCoeliacs disease and on the other, tests and characterization of the biological activity of certainfood constituents. In both cases these are novel and distinctive research areas at the IATA, withprocured funding, and they are also involved in the aforementioned Consolider project. Also,among the members of this these groups they maintain joint activities in funded projects andalso collaborations with other researchers of the IATA. For all these reasons it must beconsidered both suitable and convenient to maintain a research area into Functional foods andingredients at the IATA, which reflects and projects at a national level a relatively importantactivity, but which only comprises one sub-line exclusively in the general research area. Forthese reasons we assess this to be an emerging research line.

- Food Biotechnology - Status: Consolidated - Justification:The food biotechnology research area encompasses four sub-lines, with a total of

22 researchers and represents, thus, the line with most scientific staff at the IATA. Most of theindicators measuring the scientific work in this area reflect a competitive nature, which takeson projects funded by both national and international Calls and with adequate scientific output.This area integrates groups of different types, those that focus on microorganisms offood-related interest, in the production of enzymes and metabolites, or in studies into foodquality of vegetables, but in which all carry out experimental biotechnological approaches, andmore recently of high performance/ throughput. This aspect is one that distinguishes thisresearch area at the IATA compared to other CSIC centres working in the food sector and that,altogether represents, a strength and potential of the IATA.Within the research area as a whole, not all the sub-lines and work groups that comprise it havethe same capacity for future competitiveness and impact. Thus, it should be mentioned that thegroups working in biotechnology of enzymes, which carries out very diverse activities, rangingfrom protein engineering to the biological activity and characterization of peptides, or the groupworking on filamentous fungi, which is a topic with a long-standing tradition, have fewer humanresources, which could threaten their future potential. In other cases, however, studies intoyeasts of interest in the food industry outnumber these as they deal with different processes offood production in which these organisms are used (baking, wine-making, etc.), as well asexperimental approaches and other related topics, altogether represent a strength of thisresearch area and one of the best equipped. Work being carried out on lactic bacteria isanother distinctive characteristic compared to those carried out in other laboratories at CSICcentres working in the field of foods, as it encompasses research ranging from metabolicengineering to prebiotics or food properties. The incorporation of the sub-line working onvegetable foods is recent and well-coordinated with the progressive biotechnologicalapproaches that this working group is applying to problems of quality and preservation ofvegetable foods. It also represents a group with research potential dealing with differentaspects of the problem. This diversity of disciplines in matters related to foods, using abiotechnological approach, represents one of the greatest potentials within this research areaat the Institute. In the area as a whole and in its future projection, new technologies for global analyses shouldbe used that are complementary to those used at present, extending the projects to new food

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processes and products. Such activities could be carried out with the appointment of newresearch staff with training in these disciplines or with the capacity to carry them outefficiently. This may be the weakest aspect which should be addressed during this strategicplan.

Critical Analysis of Services

- MANAGEMENT - Status: Consolidated - Justification:The Management service unit, which also includes, administration, contracting

goods and purchases and the general services, can be defined in a general way that isconsolidated and functions optimally. Different aspects are involved in this service and aresuitably performed, with a good degree of effectiveness and responsibility. The managerial andadministrative tasks should be highlighted as in general terms they are performed properly,both those connected with the internal management and those providing support toresearchers, like administrative management. In recent years the CSIC has received greaterautonomy in its management, which has provided advantages, but has represented a greateradministrative load. This aspect is one of the problems deriving from this service, which innumerous situations suffers the consequences of management that is not carried out directly,but must act as an intermediary of processes governed by the central body.

The lack of clarity or of standardised procedures with the central body generates difficulties inthe daily management of the service. Excessive bureaucratization in some procedures ofcentral administration complicates activities and reduces its effectiveness, at the same time asit is a disadvantage to research work development. This IATA service comprises efficientworkers generally speaking with work capacity and responsibility, which makes it efficient. Inrecent years several workers have left without full replacement and within the period of thisstrategic plan there are going to be further retirements that can jeopardize the tasks of thisservice unit. This situation can be especially problematic if retirement of the present managertakes place, thus prior measures must be taken so eventual replacement takes place with asfew problems as possible. Likewise, retirement of the managerial secretary must be anticipatedin time and properly covered. Within this service, the purchase store-room must be promoted and improve its performance.Its activity has direct influence on research tasks and at the moment its benefits are limited.The staff withdrawals that have taken place have meant that at the moment there are only twopersonnel taking care of all the demands, which is insufficient to undertake all therequirements. An internal procedure has been initiated to place orders online, which has proveda good tool, but the computer system must be improved, and make it possible to offer newservices, so improvements to the Institute?s computer equipment are necessary. In summary, anew qualified member of staff must be recruited and the computer systems must be utilised tofacilitate the management of these tasks. A final comment on the management unit is needed to indicate the excessive level ofresponsibility and administrative workload that it must take care of, which again exceed thereal working capacity and causes problems in the management task. The management unitshould be freed of scientific-type tasks, and concentrate on the administrative andmanagement tasks, and a technical deputy director should be named to take charge of thesupervision and suitable operation of the scientific services. In this organigram the coordinationbetween all those in charge and the management unit would be essential to provide the correctoperation of these

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- Library and Scientific Documentation - Status: Consolidated - Justification:The Library service has demonstrating excellent performance throughout recent

years, with a high degree of performance and efficiency. Three civil servants from the CSIC areworking in this service at present and a contracted JAE tech. Despite the low number of staff,the service is well taken care of and has gained distinction within the IATA and also amongothers from our surroundings. It has enabled a very high level of computerized services to beimplemented, both directly and for external requests. In addition, the assistance withbibliographical searches, documentation, etc. are highly suitable. One situation that can be seen as a threat is the recent promotion of the person in charge ofthe Library to a post of official research scientist. Although at the moment their dedication tothe Library tasks is guaranteed, measures should be taken to foresee their possible absence inthe future. In this respect, a strategy is proposed in this section to improve the resources in thisservice and to set up new organization that maximizes the resources and performance.

- Computing and statistics - Status: Regression - Justification:The computer-science service constitutes one of the vital elements in scientific

work at the IATA, like other research institutes. At present it comprises four people, only one ofwhom is administratively considered as a computer technician. Activities in this service unithave increased progressively in recent years and continue doing so, both in the computer park,and in the information network, connectivity, Web page, an essential product with informationsystem dependence of research and administrative work. In spite of dedication and interest ofthe members of the service in assuring its proper operation, the progressive increase incomputer performance has surpassed the capacity of the same, which has caused deficiency orimpossibility to attend to all the requirements, with the consequent problems and deficientoperating capacity. A computer park of 500 PCs with the corresponding information networkexceeds the benefits that can be provided by the service. Possibly training and dedication ofsome of the members of the service is not suited to tasks at hand, and task distribution doesnot correspond to needs either. However, there is a clear need to increase the staffing in thisservice unit with specialized personnel and the need for a change in procedures. In summary, there are serious deficiencies in this service unit, both technical and related topersonnel, and their operation and performance are often a product of the personal effort andinterest of the unit?s members, faced with a clear lack of human and material resources. It isnecessary to undertake action, both in the appointment of new specialized personnel andtechnical resources, which would guarantee proper performance.

- Pilot Plant - Status: Consolidated - Justification:The Pilot plant service unit has a long-standing tradition at the IATA and has

gained distinction. The change in research activities and work needs has led to a decrease inthe use of the pilot-plant facilities and to a change in the procedures. At the moment the samethree civil servants work there, two with a long-standing tradition and junior research scientistof recent appointment, requested in the previous strategic plan. This appointment has beennecessary and opportune, since the worker in charge of the Plant is less than two years fromretirement, and giving the opportunity for a period of learning to adapt to the functions whichneed to be replaced. The service has improved in certain aspects of performance andimprovements and adjustments are being carried out in these facilities, which will improve itsperformance.The degree of efficiency is suitable and provides good support to the technological tasks carried

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out. Involvement in the activities it carried out must be improved and it should take a moreactive role. Besides the research-support tasks, it carries out teaching tasks, givingtheoretical-practical classes within the Degree of Food Technology and the Diploma in Nutrition,and in the Professional Training Schools. These activities are one of the strengths of the serviceand the IATA, since they allow its implementation in teaching, make the facilities profitable,providing external services and a source of income. General assessment of the Pilot-plantservice unit is positive, consolidated, but can be improved and has future potential.

- Maintenance - Status: Regression - Justification:The IATA maintenance service is one of the main problems currently detected at

the Institute. This is due to the fact that there is only one permanent worker in this service,which is clearly insufficient. In past years this service comprised 3 to 4 people, depending onthe time period, and they dedicated their attention to the maintenance and general operatingof the IATA services and facilities, as well as that of the scientific equipment of the researchgroups. The personnel in this group comprised a Head of Section or person in charge of thebureaucratic aspects and the rest were maintenance workers. The workers requested transferto other administrative destinations and at present there are uncovered vacancies. Given thecontext, the present service is unable to take care of the requirements generated by aninstitute the size of IATA. The new facilities and extension works underway will aggravate thisproblem. Therefore, this is clearly representative of a service that is currently in regression andwith serious under-staffing, constituting a serious hurdle to the proper running of the IATAfacilities, as well as its scientific work. Urgent measures are necessary to mitigate problems inthis key service, but contracts must be stable and thus guarantee its correct operation mediumto long term.

- Research Support Unit: Genomics, Cell culture and Microscopy - Status: Emergent - Justification:This experimental laboratory supporting genomic, proteomic, cell culture and

microscopy techniques was created just over a year ago, with the appointment of two seniorresearch scientists who, together with a junior research scientist, who make up the laboratorystaff at present. This was requested in the previous Strategic Plan 2004-2008 and is thereforedescribed as an emerging service.

The three qualified people in this service unit are in charge of different fields and instruments,in an attempt to cater to the demands that arise and to acquire a suitable degree ofspecialization. The creation of this laboratory coincided with that of the cell-culture facilitiesand the IATA has made an important investment in preparation of the laboratory andacquisition of equipment. Services rendered from the start have increased progressively and atpresent they are covering demands very suitably, this is a service with a very satisfactory levelof efficacy.

This evaluation is due mainly to the capacity, knowledge and attitude of the members oflaboratory, who are currently demonstrating willingness and interest in their activities. One canconfirm that the creation of this service has been very positive and its improvement, promotionand expansion constitute one of the proposals within this strategic plan. Once the effectivenessof laboratory has been demonstrated and that this fact has involved scientific support andample use by the IATA, it must now be equipped with new organization and working systems, tomake it even more efficient, at the same time providing services to new laboratories in

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extension underway, and the equipment.

General Objectives

General Objectives,Goals?

The general objective of IATA is to develop fundamental, multidisciplinary and applied research toprogess and generate scientific knowledge and technological development in the area of FoodTechnology and Science. This objective is carried out through four research lines focussing onbiotechnical applications in food; food preservation and safety, food quality and properties, andfunctional foods. Our mission also seeks to contribute to the preparation and training of new scientists, thecorresponding technology transfer to the industrial sector and also facilitate the public disseminationof science by means of complementary activities in education and diffusion. To achieve this, IATAshould focus its efforts on consolidating the leading research groups and promoting or encouragingnew research lines and groups, in order to improve their potential. The aim is to place the Institute ina leading position nationally and internationally, making it competitive wihin the scenario of FoodScience research.

Scientific objectives

Food Biotechnology

?Characterization of microorganisms of interest in the food sector and of new strains with improvedcharacteristics. Biotechnological and high-throughput technological approaches to identify metabolicpathways of interest and adaptive responses to stress situations. Use of microorganisms asbiofactories to produce molecules of interest in food processes.?Studies of structure-function of enzymes with improved properties.?Biotechnological strategies to design molecules with functional properties and to use yeasts as asource of nutraceuticals. ?Mechanisms of pathogenesis and virulence associated with food microorganisms.?The mechanisms of prebiotic effects.?Study of the metabolic pathways involved in the quality and nutritional characteristics of vegetablefoodstuffs and the responses of fruits to post harvest preservation conditions. ?Physiological and molecular studies of the fungi-fruit interaction, identification of virulence factorsand identification and design of anti-fungal agents.

Food Quality and Properties

?Mechanisms involved in stimulation of taste, smell and flavour by food matrices, and factors thatinfluence the consumer?s perception of food and their final response. ?Studies of new manufacturing techniques, elimination of fats and sugars and addition of bioactiveingredients and effects on the sensorial physical and properties of foods. ?Development of new strategies, study of interaction between ingredients, additives, processes anddetermination of functional and molecular parameters to obtain cereal derivatives with superior

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organoleptic and nutritional qualities. ?Improvement of processes, quality and safety of meat products by detecting markers and key toxiccomponents. Development of new healthier meat products, with improved colour and flavour andhigh nutritional value. ?Optimization of technological processes to obtain juices with high organoleptic quality, studies ofchemical and enzymatic changes during preservation and effects on its components, anti-radicaleffects and sensorial quality.

Food preservation and safety

?Develop molecular and immunological methods for rapid detection of pathogenic microorganismsand chemical residues in foods. ?Advanced methodologies to analyse chemical agents contaminating foods and studies ofbioavailability and toxicity. ?Impact of minimum processing and emerging technologies on food microbiology and quality. ?Progress in abiotic and biotic risk-assessment techniques in foods ?New food-packaging technologies, systems and materials, and studies of packaging-foodinteraction. ?Development and evaluation of new material based on nanotechnology for application to foodpackaging and micro encapsulation.

Functional foods and ingredients. ?Studies of the interaction between intestinal microbiota and Coeliac?s disease or obesity. ?Identification of new probiotics and evaluation of their functionality. ?Identification of the effects of food components in degenerative diseases, aging and evaluation oftheir bioavailability. ?Develop methods to develop functional ingredients in vivo, derived from vegetable foods andapplication of high-throughput technologies to analyse their functionality.

Knowledge Transfer objectives

The objective of the IATA in technology transfer issues is to continue collaborating actively with theindustrial sector via the means developed in previous years. These activities must be accompaniedby new efforts to boost all types of action that help to promote more effectively and productively theexchanges and the collaborations with companies in the sector. In the past the IATA hasdemonstrated it capacity to generate ideas and develop patentable research products that havegiven rise to several technologically-based spin-off companies and must aim to promote theatmosphere and conditions for new activities like this to be generated. Action should be taken tofacilitate researchers in developing patents and help in exchange with the corresponding offices.

Training objectives

The IATA must continue with its demonstrated capacity of training, including in research stafftraining, graduate training and secondary education. With respect to staff in training, we shouldcontinue to promote the entrance of new postgraduates with interest in science and research, and tobe a source of generating scientifically trained staff, which can be incorporated into the industrialsector or continue a career in research. The involvement of numerous IATA research staff inuniversity teaching is one of important training tasks, which should be maintained and adapted tonew university systems of postgraduate and masters. The IATA has traditionally participated andcontinues to run activities in training personnel working in secondary education (Professional

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training). The new pilot-plant facilities, along with the interest demonstrated by correspondingcentres, create the conditions to enable these activities to continue.

Outreach objectives

Increase dissemination activities and promote all types of activities to increase IATA?s public impactand to help the diffusion of science, in particular Food Science and Technology, must remain anobjective. Scientific dissemination should be carried out through publication in specialized as well asmore general magazines. The IATA has maintained strong presence and participation in numeroustypes of events, visits, seminars, debates, mass-media presence, which all contribute to publicdissemination and this goal must be pursued.

Internationalisation objectives

The IATA must continue to maintain and promote the presence of its researchers is numerousinternational organizations. At the same time encouraging projects and activities of all types outsidethe centre must be continued and, especially those in Latin America, where exchanges andcollaborations traditionally take place. Likewise we maintain our goal of increasing activities ofparticipation in European or other types of projects (integrated action, etc.) with countries in ourproximity. Finally, we must continue and promote training graduate students from abroad at IATA.

Common services objectives

The general goals of the service units are to provide suitable and efficient assistance to the researchtasks in different work areas. It must maintain the degree of support in research management, andmainly improve the technical and computer maintenance services of the Institute. It is necessary tomaintain the running of the library and avoid deterioration in its performance.

The services of the genomic, proteomic, cell-culture and microscopy support unit have demonstratedthemselves to be efficient and have fulfilled the expectations raised at the beginning of previousstrategic plan 2005-2009. We propose the goal of improving the facilities, by equipping the unit withnew resources, and extending its competencies and responsibilities, as well as organizing it moreefficiently.

Gender equality objectives

The IATA does not consider implementing specific actions of gender equality. Imbalances in thisrespect have not been detected and until now no gender conflicts have occurred. As an example, wewould like to mention that among research staff there are 31 women and 25 men. These dynamicsshould continue, applying criteria of quality and preparation in when recruiting personnel in thedifferent categories.

Quality programmes objectives

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The IATA does not propose to take specific action in quality programs in the near future. However,certain working groups has shown interest in putting their research activities to test in order tovalidate them via norms and suitable quality programs, as a previous step to other future transferactions or provision of external services. The IATA will give all the necessary aid and collaboration sothat these initiatives are carried out and will encourage others in this same direction.

General Strategy

Summary

The general strategy encompassed by this strategic plan for the IATA, tries to guarantee andimprove the quality of research and technological development taking place at the institute, therebyimplementing the necessary resources and maximizing effectiveness. This scientific strategy mustconsider the investments made in the building extension work currently underway and expected tobe completed when this strategic plan is in force. With these new facilities the IATA will have ampleinfrastructure and capacity, enabling it to propose and deal with new scientific objectives and othertypes of goals that are not possible at present.

This strategy proposes two criteria to be followed at the scientific level: aim to strengthen andpromote the competitive research lines and sub-lines that currently have fewer resources in terms ofscientific staff and may be threatened; and, secondly, deal with new scientific objectives which allowexpansion of the research dimension and incorporate new issues or experimental strategies. In thiscase, and without going into detail, we can mention some examples like rapid detection methods ofmicroorganisms or chemical pollutants, sensorial analysis, food processing and preservationtechnologies. Among new areas of work we envisage those connected with studies into the actionmode of foods or their ingredients, use of microorganisms as biofactories or sources of componentswith nutritional properties, and the application of high-performance technologies. This strategy mustnot exclude other research lines/sub-lines, which despite being better equipped, raisecomplementary targets of quality, which allow improvement of their capacity.

This proposal requires the incorporation of new methodologies, among which those of highperformance should continue to be implemented (genomic, proteomic, metabolomic), cell cultures,technologies to identify chemical components and other metabolites in foods, developments inimmunoassays and new applications derived from nanotechnology, which are emerging in thecentre. The nature of these methodologies and new approaches requires collaborations to be set upwith others centres with equipment and experience, optimizing and sharing resources, since thelevel of investment required is not always affordable. In addition, the common services within theIATA should continue to be improved, equipping the institute with the necessary personnel andresources, and new performance potential and equipment should be based around these commonservices, instead of being individualized.

In order to develop this scientific strategy properly it is essential to select the new staffappointments carefully, observing mainly criteria concerning quality and competitiveness, and inmost adequate topic areas at each moment. The strategy should consider contracted postdoctoralresearchers (Ramon y Cajal, senior JAE., etc.) in order to guarantee quality criteria and overall totake care of fields that we want to promote.

This strategic plan will continue to pay attention to dissemination activities, for which personnel are

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appointed, using the channels that have proved efficient and, improving and increasing the volumeof visits, diffusion and external relations, etc. The specific measures of this strategy are given indetail in the following sections, but research must be directed at maintaining the IATA in acompetitive position nationally and internationally, by equipping it with the necessary humanresources and equipment. These measures must be taken in order to distribute and use the newfacilities rationally, where the general services and laboratories can be improved, to take care ofnew staff appointments and to cover the requirements of space over the coming years.

Strategy Analysis

The strategy designed here exploits the strengths outlined in the SWOT analysis. It aims to achievethe goal whereby the competitive groups with greater human resource capacity are able to take onnew scientific approaches and projects or proposals, like those outlined previously. In the area ofbiotechnology, and in particular in the sub-line dealing with yeasts and fungi or vegetable foods, orin sub-lines encompassing cereals and meat products, in the quality and properties research line andthe sub-line dealing with packaging and applications of nanotechnology, where the number ofresearch workers is higher, they are better prepared to deal with these new approaches and to takeadvantage of the potential benefits they offer.

The proposals made, both in terms of human resources and other resources, focus on existingresearch lines or sub-lines that are deficient or under-staffed, thus attempting to compensateweaknesses.

-As in the previous strategic plan, we aim to promote strategic and competitive groups at the IATA,but the focus of the current strategy is on groups with clear staffing deficiencies or with forthcomingretirements, which must be implemented whenever necessary.

-We aim to promote the capacities of the genomic, proteomic, cell-culture and microscopy supportservices, in such a way that this area of activity which is clearly important in the IATA, and superiorto that of other CSIC centres in this sector, continues to grow and be consolidated by offering newservices.

- The difficulties in acquiring resources can be alleviated if common strategies in acquisition ofequipment are shared and they are focussed on common services. Thereby, other complexmethodologies in which different IATA groups are interested (HPLC-MS, GC-MS, NIR, among others)could also constitute a new service unit, equipped with qualified personnel, with the consequentadvantages such a service could afford.

- Likewise, the scientific strategy aims to equip and promote IATA?s potential capacities in complexanalytical techniques, which have lately been acquiring new implantation in our scientific area. To doso, the institute proposes the creation of posts for the appointment of a Tenured Research Scientistand a Senior Research Scientist, in order to equip the human resources with staff who canimplement and develop this scientific-technical strategy.

? Increasing the performance and working capacity of the pilot plant, as well as the laboratories foruniversity training practices, implies consequent improvement of IATA?s potential in this ambit. Toachieve this we make a proposal to create a place for a Senior Research Scientist to replace theforthcoming retirement, with the purpose of promoting the technical performance of the service.

- With respect to future staff appointments of new senior JAE researchers at IATA we propose that

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such appointments are not requested in advance for specific research lines, but rather a jointrequest is made for those considered suitable, in such a way that competitive candidates can applyfor annual Calls that are not restricted to specific groups annually. We consider that this strategy canhelp us to later select the most suitable candidates for specific staff appointments. These are thereasons why we request that the senior JAE appointments are made solely by the Institute.

? It has been agreed that the strategy concerning the appointment of research assistants should bedone in a similar way to that previously outlined, by means of the Institute requesting assistants. Theassistants that are appointed along with those to cover vacancies, will be assigned to the differentsub-lines and research groups following criteria of orderly and balanced distribution among thedifferent laboratories and taking care to tackle problems related to short-staffing.

- The strategy also aims to favour the activities and collaborations with surrounding centres atvarious levels. Increasing collaboration with our closest associate units and universities, ourrelationships with the UPV and with the IIAD are a good example. We already share facilities with theUVEG, and there are assistant professors at the IATA and an important involvement in teaching.

- The strategy must also be directed at solving weaknesses caused by the lack of certain equipmentthat could pose a threat, since the necessary investments cannot be taken on. Use of the nearbyUVEG animalarium, sequencing services and other technology afforded by the UVEG, the protemicservices offered by the Prince Felipe research centre, the genomic and metabolomic services of theIBMCP, are examples that afford solutions to these problematic situations.

- The proposed dissemination and recruitment activities and involvement in university teachingactivities attempt to alleviate the threats posed by lack of motivation in science, and recruit studentswho intend to pursue a research career.

- The IATA has proven itself both capable and economically solvent enough to create, from itsresearch developments, technologically-based spin-offs and even be the origin and nest of thesecompanies. To continue taking advantage of these opportunities could constitute one of IATA?sstrategic plans. New laboratories afford possibilities in this sense, acting as niches set in suitableresearch scenarios with latest developments in the sector. These can constitute technology transferand some of the technologies developed at IATA can even be offered as external services, all theseare possibilities that should not be overseen.

Outreach

In recent years the IATA has made efforts in disseminating science and its lines of work throughdifferent channels. In the strategy that has been designed for the four-year period underconsideration, we aim to maintain at least the same level of activity and promote those that haveproved more successful. To do so, the following actions are proposed: ? Keep the research worker Maintain who is currently dedicated to scientific dissemination tocontinue with the same type of activities, being in charge of organizing the habitual guided visitsthat take place of secondary education centres and professional training centres, bridge the gapbetween the activities carried out in the CSIC Delegation in the Comunidad Valenciana and the IATA.This worker will also continue searches of relevant scientific news and its diffusion via the Web page.

- A television screen has been installed in the reception hall of the IATA to project the latest IATAproject news and CSIC news, and promotional videos are also available of the research institutes andof the UVEG Scientific Park. This system will be kept up, increasing its performance, projections andthe amount of news. - Design a new, more attractive, modern and interactive Web page, where IATA activities can

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achieve greater projection and impact. - Design an informative brochure to give to all the visitors attending presentations at the IATA. - Increase the number of visits and participation of students from different educational levels. - Participate with the surrounding institutes in a new application for a scientific dissemination project,similar to that already funded in 2007.

Internationalisation

-Maintain and widen international collaboration contacts-Request that the Virtual Centre of Filamentous Fungi and Yeasts of Valencia (CVLV) be consideredas a Marie Curie Training Site. This will allow us to host students from different member states orassociate members of the EU. -Establish collaboration agreements with Latin American Universities for training students andshared projects -Participate in various European Union committees such as the European Food Safety Authority(EFSA).

Quality Control Programmes

Activities of this type have not been anticipated, we consider that in the present conditions andgiven the level of the services offered, specific quality programs are not required. However, someresearch groups have shown interest or are considering taking part in specific quality programs inview of future service transfer activities. The IATA will favour and help these types of initiatives andwill make resources available so that action can be taken to participate in specific quality programs.

Gender Equality

The gender-parity ratio very well balanced at the IATA and in some groups the proportion of womeneven exceeds the men. In the last two years, 5 women have been appointed as compared to only 1man. No reasons have been detected to consider it necessary to take action on this respect.

Knowledge Transfer

The intention is to continue a policy of publishing the results of our research in those scientificjournals with the greatest possible impact and present the results of research at scientificconferences and also in conferences attended by professionals in the food sector. Increase the difussion of the activities of the IATA at regional, national and international levelpromoting cientific seminars, visits and interchange with other scientific people

Estrategy on Research Lines

Global actions

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- Línea de Investigación General del Centro - Action to execute: Bolster Priority: 1 - Justification:The actions proposed by the Institute with respect to its research lines attempt,

in the general sense, to improve the performance capacity of the research groups, strategicallypromoting those sub-lines that they consider competitive and of added value to the IATA, butwhich for different reasons (lack of human resources, retirements, etc.) could see their performance capacity threatened in the coming years. On to other hand, action would be takento maintain and improve the potential of other lines that have larger research teams or haveincreased the number of researchers, so they can take on new strategies and objectives withinthe topic area of their work. As mentioned previously, the appointment of JAE-PhD and JAE Sen., must be the previous step to assessing candidates? abilities, their suitability and adaptation,thereby enabling us to take suitable decisions for future permanent staff appointments. For thisreason, there has been a consensus at IATA deciding that this offer should be made jointly andthat candidate groups can compete for the offers annually, instead of predeterminingallocations that are not always successful.

At the IATA there are clear synergies and common points existing between different researchareas, as well as methodological interests and clear affinities. Advantage should be taken ofthese conditions which are useful to create common services, share resources and equipment,and another series of activities that can take advantage of the resources and maximizeperformance. In this sense, the creation and promotion of the genomic, proteomic andcell-culture and microscopy service unit has proven itself to be effective the decisions of thisstrategic plan wishes to encourage the research teams to use these resources, share thebenefits and that the personnel of this unit involves itself in the activities of the researchgroups. Similarly, we envisage the institute being able to act in the same way in otherphysico-chemical analytical techniques, and therefore, request a Senior Technician to be incharge of the maintenance of equipment and provide technical assistance to researchers. Inaddition, we request a Tenured Research Scientist to help develop projects in which thesecomplex techniques are applied to food science. The increasing demand for more complex andsophisticated techniques, along with the high cost of the equipment, make this type of decisionboth necessary and justified.

In groups working in biotechnological applications, synergies are also clear and they sharecommon strategies in numerous activities and requests. The set of research lines, as a whole,dealing with problems and issues connected with microorganisms would be helped by takingcommon action. It is worth highlighting that several of the profiles requested in the followingsection, by certain research lines, may be of common interest and share affinities with otherresearch lines, and furthermore, future incorporations in this respect could collaborate andinteract with different groups. This situation is true for different research lines, as well assub-lines within a wider area. In this sense, some of the professional profiles requested by the biotechnology research line,which are numerous, could incorporate a researcher who is competently qualified to deal withdifferent topic areas as well. With respect to equipment, the actions taken follow a similar lineof reasoning, and numerous requests are made for equipment to be shared by several users.Availability of a service unit with qualified personnel can help us adopt similar strategies to dealwith the more complex and expensive equipment necessary for certain techniques.

- Food Quality and Properties - Action to execute: Bolster Priority: 1 - Justification:The actions proposed aim to promote the different research sub-lines and groups

by appointing Tenured Research Scientists to complement the current activities or help dealwith new topic areas, as well as continuing to train research staff. The professional profilesproposed, and justification for these, are as follows:

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1. New food processing and preservation methods.2. Application of advanced analytical techniques 3. Sensorial analysis of foods4. Development and validation of new foods or functional foods

.The first profile requested is justified by the need to promote the research line in fruit juices,which is strategic in the Comunidad Valenciana and in the citrus sector, since the average ageof the members of this sub-line is high, with forthcoming retirements within this strategic plan,and this justifies staff reinforcement by qualified scientists, who can continue research into thistopic area. Application of advanced analytical techniques is justified by the research groupsworking in this line, since they have previous experience and skill, and enough knowledge offood processes to implement new staff appointments efficiently. The sensorial analysis of foodsis one of the areas with deficiencies that have not covered in years past, and where continuityis seriously threatened by the retirement of the head researcher. Finally, validation of new andfunctional foods is one of the latest areas in Food Science and Technology, and the researchline has made excellent contributions in this topic area. To implement and promote research inthis future area of impact is an action that is of interest to the Institute.

The proven ability of the research groups in terms of research-staff training in these topicareas, justifies the actions proposed concerning pre and postdoctoral JAE staff.

- Food Preservation and Safety - Action to execute: Bolster Priority: 1 - Justification:The actions proposed aim to promote the different research sub-lines and groups


1. Food safety2. Evaluation and detection of toxins and pollutants in foods3. New food packaging technologies and applications of nanotechnology

- Functional Foods and Ingredients - Action to execute: Consolidate Priority: 2 - Justification:This research area, composed of only one sub-line, does not request professional

profiles corresponding to Tenured Research Scientists

- Food Biotechnology - Action to execute: Bolster Priority: 1 - Justification:The actions proposed aim to promote the different research sub-lines and groups


1. Biochemistry and Engineering of Enzymes.2. Improvement and selection of microorganisms of interest in the food industry3. Biotechnology of metabolites of alimentary interest

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4. Biotechnological applications to functional foods and/or food safety.5. Application of high-throughput technologies to foods (genomic, proteomic and metabolomic).

Staff actions

- Línea de Investigación General del Centro - TS: 0 HSO: 0 IST: 0 RA: 0 PosD: 0 PreD: 0 Senior: 0 Tec: 0

Priority: 1

- Food Quality and Properties - TS: 4 HSO: 0 IST: 1 RA: 0 PosD: 4 PreD: 5 Senior: 0 Tec: 0

Priority: 1 - Justification:The first profile requested is justified by the need to promote the research line in

fruit juices, which is strategic in the Comunidad Valenciana and in the citrus sector, since theaverage age of the members of this sub-line is high, with forthcoming retirements within thisstrategic plan, and this justifies staff reinforcement by qualified scientists, who can continueresearch into this topic area. Application of advanced analytical techniques is justified by theresearch groups working in this line, since they have previous experience and skill, and enoughknowledge of food processes to implement new staff appointments efficiently. The sensorialanalysis of foods is one of the areas with deficiencies that have not covered in years past, andwhere continuity is seriously threatened by the retirement of the head researcher. Finally,validation of new and functional foods is one of the latest areas in Food Science andTechnology, and the research line has made excellent contributions in this topic area. Toimplement and promote research in this future area of impact is an action that is of interest tothe Institute.


- Food Preservation and Safety - TS: 3 HSO: 0 IST: 0 RA: 0 PosD: 4 PreD: 5 Senior: 0 Tec: 0

Priority: 1 - Justification:Food safety is one of the strategic areas in the IATA. The profile requested aims

to promote activities with lower working capacity, like those related to the application ofmolecular detection methods of pathogens, emerging pathogens in foods, which willcomplement the present lines. The second profile required is of a strategic nature, since it isfocussed on evaluation and detection of pollutants, especially pesticides, in foods, by means ofimmunological techniques. This research line began a few years ago in the IATA and has goodperformance indicators, thus we propose supporting it with a new scientist who would help toconsolidate it in the Institute. Finally, in the area of food packaging, progress has been madewith respect to traditional packaging systems, moving towards active or intelligent packaging,encapsulation, etc, making use of new materials. Nanotechnology has helped in developingthese systems with the multiple possibilities that it opens up. With this profile we aim to be ableto deal with new applications in the developments carried out at the IATA, since the centrealready has the appropriate methodology, experience and scientific surroundings in which theycan be implemented in a complementary and efficient way.


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- Functional Foods and Ingredients - TS: 0 HSO: 0 IST: 0 RA: 0 PosD: 1 PreD: 1 Senior: 0 Tec: 0

Priority: 2 - Justification:This research area, composed of only one sub-line, does not request professional

profiles corresponding to Tenured Research Scientists. The reason for this being that the linemust consolidate its research activities at the Institute, contribute to personnel training andrecruit postdocs and, in subsequent steps, once they have acquired greater stability via theconcession of projects and consolidated their track-record in the area, actions related to staffingwill be considered. It would, however, be convenient if they could have the help of personnel inpredoctoral and postdoctoral training, who would help and collaborate in the workencompassed in this sub-line.

- Food Biotechnology - TS: 5 HSO: 0 IST: 0 RA: 0 PosD: 6 PreD: 5 Senior: 0 Tec: 0

Priority: 1 - Justification:Within this research area, that studying the biochemistry and biotechnology of

enzymes is one of the most under-staffed areas, and its performance could thus be affected inthe future. For this reason, this sub-line needs to incorporate competitive researchers to boostperformance. Approaches oriented towards characterization and selection of microorganismswith improved properties for use in industrial food processes is an aspect that iscomplementary to those traditionally carried out in this research line and could constitute aninteresting area of activity and with the ability to interact with others. Other future approaches that can be dealt with in this research area include thebiotechnological characterization of inert metabolites in foods, either with nutritionalcharacteristics or for adaptation to stress, with bioactive properties, or of another nature, bothin microorganisms and vegetables. For this reason, we consider it of future interest to be ableto establish, within the main line, a specific approach to deal with these issues. In acomplementary way to the previous considerations, a new scientific profile should includebiotechnological applications focusing on new aspects of food science, like functional foods orfood safety, which have lower representation in the general context of the research line.New experimental approaches in biotechnology, biochemistry or metabolism make use of theso-called high-throughput technologies (known as omics) that have opened up a new dimensionin these studies. The requested profile tries to implement and directly promote this type ofmethodology, which can be applied to diverse biological situations and food substrates, butwith a view to helping establish these methodologies in the Institute in a coordinated way, witha service unit dedicated to this topic area.


Equipment actions

- Línea de Investigación General del Centro - Action to execute: Increase Priority: 1 - Justification:We had included in this general section of the IATA, three pieces of equipment

that have been asked for by very many researchers at the IATA and that are intended forshared use by researchers of the Institute. One is an ultra-centrifuge that is general equipmentand of which there of only one existing at the IATA that is old, causing multiple problems andwhich needs replacing. The request for an ion trap is justified by numerous demands fromresearchers for this type of system, which is used in compound characterization analysis usinghigh resolution techniques. The IATA does not have this equipment and its acquisition willrepresent an important advantage to a research line working in a topic area of interest that we

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wish to promote. The other requested equipment is a PTR, which is a system used to carry outanalysis of the volatile fractions of foods in real time. These types of work are done in severallaboratories at the IATA using other methodologies. Availability of this equipment will representan added value and will allow us to improve quality, performance capacity and reproducibilityof the analysis.

- Food Quality and Properties - Action to execute: Increase Priority: 1 - Justification:Acquisition of a calorimeter is requested in order to carry out measurements

connected with the degree of ?crunchiness? and texture of foods, which is one of topic areasdealt with by the Physical and Sensorial Properties sub-line. The second piece of equipment,requested for 2013, is a HPLC to replace the one that is currently in use and that is worn outand out-dated. The remaining requests comply with the need to properly maintain and repairsome of the equipment in the pilot-plant and sampling-room, which date from the opening ofthe present facilities, and need to be updated and renewed.

- Food Preservation and Safety - Action to execute: Increase Priority: 1 - Justification:A high-priority petition is for atomic-absorption equipment, which is essential for

the work carried out in the determination of metals and trace elements in foods. The presentequipment is outdated and causes continuous problems and it is necessary to replace it. Theother two pieces of equipment asked for are justified by the packaging and nanotechnologysub-line. In the case of the atomic force microscope, its acquisition will allow greater resolutionin the analysis of the characteristics of particles and surfaces of the material being developed,and would offer added-value to the group?s performance capacities. The mini-extruder andmini-injector would replace low performance equipment we currently possess. Researchers inthis line currently make use of new equipment housed at the ITENE (Institute of Packaging andPacking), with which it collaborates, and for that reason acquisition for the IATA would beadvisable.

- Functional Foods and Ingredients - Action to execute: maintain Priority: 1

- Food Biotechnology - Action to execute: Increase Priority: 1 - Justification:This research line requires an HPLC for its work related to food properties,

analysis of metabolites, etc. and currently they do not have one. At the same time, acquisitionof a refrigerated shaker tower is a demand common to different research groups, since manymethodologies are shared and the equipment is of great and frequent use. Finally, researchersin this research area will be able to reclaim the pilot-plant facilities, which have been beingused by Biolopolis SL since 2003, a company whose main share-holder is the CSIC, housedinside the IATA. These facilities, of around 250m2, will need to be prepared: furniture must bebought as well as basic laboratory equipment and other types of basic actions in order to makethem operative again for use by researchers of this department.

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Estrategy on Services

Global actions

- MANAGEMENT - Action to execute: Bolster Priority: 1 - Justification:Staff appointments: 3 assistants. Two of them will take care of administration and

1 will take care of the warehouse and purchases. Application for purchase orders will be improved and we will try to establish an applicationwhereby researchers can access updated information concerning their project balance. Attempts will be made to act with foresight in the replacement of the manager in the event ofpossible retirement. Similarly, retirement of the Management Secretary will be provided for assoon as possible. These actions, and those that are derived from those taken in other services, shouldprogressively lead to a management free from the direct supervision and organization of otherservices, but maintaining economic control, and thus enabling it to concentrate on themanagerial and administrative tasks at hand.

- Library and Scientific Documentation - Action to execute: Bolster Priority: 1 - Justification:This service, as already mentioned, operates well and offers suitable services.

The library is peculiar with respect to two of its members: the person in charge of the libraryand the publishing officer in charge of the magazine have been promoted to the level ofTenured Researchers by internal promotion. Therefore, we consider that this service should beequipped with sufficient staff to allow it to take care of its services and for the twoaforementioned workers to be able to coordinate their research tasks too.

On the other hand, at the moment a series of support services, like the one responsible formaintenance of the Web page, graphic design and the researcher in charge of scientificdissemination tasks, are dispersed. The process designed here tries to group all of themtogether in a single service unit, in such a way that resources can be maximized and tasksorganized properly, since all of them are connected to documentation and scientificdissemination. Simultaneously, from this service one can have access to the sources ofinformation, scientific documentation, news, etc.This will enable better care to be taken of theIATA Web page with constant updating. Such organization will also allow better performance ofthe whole publishing process, from manuscript management to their publication in the FSTImagazine.

To do so, we will try to organize a new and improved Web page design, adapted to needs of theIATA and under the supervision of the present person in charge of the library with the aid of thepersonnel in this service and in the computer science unit. This official researcher will be theperson in charge of the service, possessing the capacity and autonomy to organize and carryout the necessary tasks and services. The process has already begun, so as to be able to fill thevacancy that has been left and in this way replace these tasks for other new functions. Thegraphic designer in charge of design is also included in this service and besides his habitualtasks will be in charge of others of more general nature.With this strategy we will try to organize a service so that dispersed personnel are groupedtogether, recovering resources and organizing them suitably, which with the proposedreplacement of personnel and new staff incorporation, can create a highly efficient service, inwhich both tenured researchers can coordinate their research tasks.

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- Computing and statistics - Action to execute: Bolster Priority: 1 - Justification:Actions to be taken in the computer-science service in order to promote it will be:

- To incorporate a technician in computer science or specialist in computer science networks,which will help in the maintenance of the equipment and the computer science network of theIATA. - To incorporate JAE technicians specialized in computer science, to help with the activities ofthis service. - To replace the forthcoming retirement that will take place in 2010 as soon as possible. Thisservice should be staffed by at least four or five personnel.

- The maintenance of the Web page will be transferred to the responsibilities and organizationof the new Library and Documentation service, freeing the present service of this activity. - Proper measures should be adopted to maintain the network, by outsourcing if necessary. Thecomputer-science personnel should be freed from routine tasks and allowed to organize thesystem properly. - Responsibilities should be shared and management and maintenance of the network and itscomponents extended, in order to cover future eventualities. - With the current extension works that are underway, we must properly estimate theproportions and forecast the future needs for Servers, auxiliary systems and all the necessaryequipment and to avoid continuous deficiencies and shortcomings, and provide an efficient andstable service that will last several years.

- Pilot Plant - Action to execute: Bolster Priority: 1 - Justification:In this service the strategy pursued should consolidate the services offered,

guaranteeing a suitable level of educational resources so that needs of researchers and otheractivities continue to be satisfied efficiently. Within the construction works that are beingcarried out at present, the infrastructure will be improved, and a small laboratory and seminarroom are being built. These works consolidate infrastructures, thus the main needs are tosuitably replace the forthcoming retirement of the person in charge with an expert in processesas well as the retirement that will take place at the end of the period covered by this strategicplan. With these staff appointments and the construction work underway, the tasks of theservice can be carried out efficiently.

- Maintenance - Action to execute: Discontinue Priority: 1 - Justification:With respect to the maintenance service the strategy must focus on urgently

replacing the vacant posts, since at the moment it is the greatest shortcoming of this service. Aprocess has been set in motion to fill the vacancies and we request two more staffappointments, which given the building extensions underway, is a suitable staff number to takecare of the services. Once needs of the personnel have been taken care of, the services shouldbe organized properly, with separation and distribution of tasks among the members tomaximize resources and performance.

- Research Support Unit: Genomics, Cell culture and Microscopy

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- Action to execute: Bolster Priority: 1 - Justification:The strategy that has been designed in this support laboratory tries to

consolidate its performance and turn it into a stronger and very efficient service. To do so weset out to extend its services, and to create a catalogue of extensive activities that can coverresearchers? needs in this topic area. The tasks and services should be distributed inagreement with the specializations and experience of the workers, and also take care of newlyacquired equipment for time-real quantitative PCR. The acquisition of new cytometric flowequipment and the fluorescence microscopy head will be organized around this service, thusextending the services offered by the unit.

We also intend to equip the service with a LC-MS to complement the proteomic tasks. Currently,the personnel of this service are considered to be well-adapted and sufficient for the servicesoffered. However, there are proposals to start setting up a service, which in principle will belocated together with the present one in new the laboratories, but dedicated to tasks related toanalytical techniques, such as gas chromatography connected to HPLC-MS, mass spectroscopy,NIR, etc. that would be in charge of offering these services to the users, and part of theequipment requested in this strategic plan will be located in this service unit. To accomplishthis, the strategy proposes the appointment of a tenured research scientist who is specialized inanalytical techniques and, by using the equipment available, should start up this researchsupport service, which is in great demand by a high percentage of researchers.

Staff actions

- MANAGEMENT - TS: 0 HSO: 0 IST: 0 RA: 3 PosD: 0 PreD: 0 Senior: 0 Tec: 0

Priority: 1 - Justification:The personnel will be distributed as follows: 2 for administration and 1 to the

warehouse and purchases. In the first case it is necessary to replace staff losses in administration (one of a civil servant that has taken place in the month of October 2008 and acontract that will finish in 2008) and to provide for a possible retirement in this service unit. Inthe second case, we intend to cater for the needs created in the warehouse the purchases,where the current staffing of two is clearly insufficient.

- Library and Scientific Documentation - TS: 0 HSO: 0 IST: 0 RA: 1 PosD: 0 PreD: 0 Senior: 0 Tec: 0

Priority: 1 - Justification:An assistant is requested, who will be destined to the administrative tasks

derived from the editorial work on the magazine. By joining the different activities togetherwithin a single service unit, performance can be improved and tasks distributed among thepersonnel more rationally. The first action to take is to replace (by means of administrativetender) the position for librarian, and the service will be fully staffed. If the vacancy owing to aretirement in 2011 is also covered, needs will be fully catered and for this reason, theappointment of an assistant can help in the administrative tasks related to publishing themagazine.

- Computing and statistics - TS: 0 HSO: 0 IST: 1 RA: 1 PosD: 0 PreD: 0 Senior: 0 Tec: 0

Priority: 1 - Justification:The requested appointments must cover the needs of the service, since a

retirement will take place in 2010. A Bachelor graduate is requested to be trained inmicro-information technology, handling PCs, software installation and complementary workneeded in the maintenance of the PC network of the IATA, and who can simultaneously help

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with the computer science network. The appointment of an assistant who can attend to taskswith lower technical requirements would equip this service with four people to take care of itsgrowing service demands.

- Pilot Plant - TS: 0 HSO: 1 IST: 0 RA: 0 PosD: 0 PreD: 0 Senior: 0 Tec: 0

Priority: 1 - Justification:In pilot plant, as mentioned previously, a vacancy will come up due to a

retirement that will take place in 2010 of the person in charge of this unit, who is a technicianwith 30 years of experience and ample knowledge of the industrial sector. Present needs, giventhe recent incorporation of a junior lab technician, require a person with experience andtraining, who is able not only to handle the equipment but to plan and design experiments, withautonomy and the ability to take decisions, and with training in the agro-food industry. Theprofile required corresponds to a Senior Tenured Research Scientist, with experience in FoodEngineering and/or Food Technology. The second place requested is for a Bachelor holder, tocomplement the personnel of this service unit from 2013, which is when the technician, who isworking there at the moment, will retire - so that there are no fewer than three specialistsworking in the group attending to this service.

- Maintenance - TS: 0 HSO: 0 IST: 0 RA: 2 PosD: 0 PreD: 0 Senior: 0 Tec: 0

Priority: 1 - Justification:As previously mentioned, at present there is only one person in the maintenance

service, which jeopardizes the performance of this service. It is necessary to extend the servicewith assistant staff to cover needs, especially given the extension works underway at IATA. Abuilding like the IATA, with 14,000 m2 of surface area and complex facilities, requires no fewerthan 4 staff, which would comprise the present person in charge, two assistants that have beenrequested and another additional person to fill the current vacancy.

- Research Support Unit: Genomics, Cell culture and Microscopy - TS: 0 HSO: 2 IST: 0 RA: 1 PosD: 0 PreD: 0 Senior: 0 Tec: 0

Priority: 1 - Justification:This back-up laboratory was created in 2007, and we aim to consolidate it in the

present strategic plan, extending it to provide other services and support. We think that at themoment the best is a nuclear set up, around a common service in research support for complextechniques, thereby sharing laboratories, resources and equipment until they reach sufficientautonomy and independence. Three professional profiles are required:

- Senior Technician specialised in analytical techniques, who would be the person in charge ofextending this service to this type of more complex physico-chemical techniques, in highdemand by researchers (GC-MS, HPLC-MS, NIR, etc.). We believe it necessary for an Institutelike the IATA to have a specialist in these technologies, to provide expert support in differentmethodologies, to help and assist in different techniques and interpretation of data, as well asto make profitable use of valuable equipment.

Senior Technician in Biostatistics and/or Bioinformatics. Current high-resolution technologieswhich are able to generate immense amounts of data require technical back-up of peoplespecialized in data design and interpretation and who can apply appropriate statistical systemsin each case. At the same time, these techniques combine the use of technically complexdata-processing systems to process and interpret thousands of data, which is only possible withspecialized equipment and complex networks. These needs are in increasing demand byresearchers at the IATA, which justifies this request.

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- Laboratory Assistant. This assistant will complement and provide technical back-up to thisservice unit, which will take on greater responsibilities and provide more services, possiblyaround the middle of this strategic plan and once the new facilities have begun working inanalytical techniques.

Equipment actions

- MANAGEMENT - Action to execute: maintain Priority: 1 - Justification:According to needs of the service

- Library and Scientific Documentation - Action to execute: maintain Priority: 1 - Justification:According to needs of the service

- Computing and statistics - Action to execute: maintain Priority: 1 - Justification:According to needs of the service

- Pilot Plant - Action to execute: maintain Priority: 1 - Justification:We request replacement of the centrifuge that we have currently. This equipment

is old and works badly, thus it must be replaced, since it is necessary for a great many activitiesin this common service.

- Maintenance - Action to execute: maintain Priority: 1 - Justification:According to needs of the service

- Research Support Unit: Genomics, Cell culture and Microscopy - Action to execute: Increase Priority: 1 - Justification:The following equipment is requested:

- Florescence Reader for the FLA-3000 equipment that the IATA already has, in order to be ableto carry out fluorescence readings in protein gels marked with different fluorophores. Thistechnique will enable the IATA to complete and improve the technological performance inprotein analysis, complementing others that are already available.- Flow cytometer. This equipment is requested by numerous IATA researchers; in fact, oneresearch group uses this methodology at services provided by the University of Valencia, forwhich it must pay. This equipment will enable IATA to benefit from it own service for cellseparation and counting, with numerous applications to experimental needs of the Institute.

-Head for the confocal microscope. Under the last strategic plan we acquired a microscope,co-funded by the researchers, with a fluorescence detector and prepared for adaptation with aconfocal head. This microscope is being widely used at the Institute and now we wish to buy theequipment necessary to adapt it to the confocal mode, which would allow higher performance

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and increase the current capacity of the current apparatus.

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Progress Indicators (Quantitative objectives)

Progress Indicators (Quantitative objectives)

Indicator 2010 2011 2012 2013Funding(k€) Research projects 1528 1239 1864 1754

I+D Contract 253 285 220 216

Article / Bookchapters (number)

HIGH Percentil 75 64 67 76 76

MEDIUM Percentil 50-75 39 40 41 42

LOW Percentil <50 3 4 3 4

Congress(number) HIGH Percentil 75 38 40 36 43



Full books(number) HIGH Percentil 75 2 2 4 1



KnowledgeTransfer(number)

Requested priority patents 1 6 0 4

Licensed priority patents 1 0 3 1

Spin-Offs 0 0 0 0

Indicator 2010 2011 2012 2013Training (number) Theses 13 10 14 16

Courses & masters (hours) 701 701 651 651

Outreach(number) Events 7 7 10 9

Material 9 11 9 10

Internationalisation(number)

Foreign staff 16 9 12 9

Colaborations 16 13 17 13

Co-authoring scientific articles 23 18 21 19

Services in English?

Services Self financing

Relative efficiency respect to

Electronic management implementation

Quality programme Integrated program

ISO certification

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Resources

Human resources

Personnel(number) 2010 2011 2012 2013 TotalTenured Scientist 2 3 4 3 12

Higher Scientific Officer 1 1 1 0 3

Intermediate Specialist Technician 1 0 1 1 3

Research assistant 4 4 4 4 16

JAE-Senior 2 2 3 3 10

JAE-Doc 4 4 3 4 15

JAE-Pre 4 4 4 4 16

JAE-Tec 3 3 3 3 12

Financial resources

Action 2010 2011 2012 2013 TotalEQUIPA(k€) 520 440 177 150 1287

- Justification: The proposals made, both in terms of human resources and other resources,focus on existing research lines or sub-lines that are deficient or under-staffed, thus attemptingto compensate weaknesses.As in the previous strategic plan, we aim to promote strategic and competitive groups at theIATA, but the focus of the current strategy is on groups with clear staffing deficiencies or withforthcoming retirements, which must be implemented whenever necessary.We aim to promote the capacities of the genomic, proteomic, cell-culture and microscopysupport services, in such a way that this area of activity which is clearly important in the IATA,and superior to that of other CSIC centres in this sector, continues to grow and be consolidatedby offering new services

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general description - csicw1.iata.csic.es/memoria/pe2010/iata-centro101.pdf · 2009-05-07 · iata...

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