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Axio Observer LSM 5 DUO PALM MicroBeamCarl Zeiss: Living Cells

Carl Zeiss MicroImaging, Inc.One Zeiss DriveThornwood, NY 105941-800-233-2343micro@zeiss.comwww.zeiss.com/fluoresscience

Understand the Dynamic Processes of Life.Reach Out for Experience.

Göttingen/Germany, October, 2006. “CarlZeiss: Living Cells”. Carl Zeiss MicroImagingGmbH presents a new microscope systemthat has been specially developed for exten-sive research of processes in living cells. TheAxio Observer, based on an inverted researchmicroscope, makes it not only possible toobserve processes in living cells, but also tomanipulate processes and analyze the result-ing changes. This is the means of obtainingnew insights, both in basic research and, forexample, the development of new drugs.Axio Observer permits the use of a wide variety of application-specific solutions.

Great emphasis has been laid on optimumoperating convenience for all technicaldetails. This is particularly evident in the ACRfunction which automatically recognizesobjectives and reflector modules, integratesthem into the system configuration and

displays them on the touch screen display.This is especially interesting when severalresearchers share one instrument. Whenchanging filter cubes or objectives for a newexperiment the Axio Observer automatically

recognizes the new configuration.

The entire microscope can be operated viashort and clearly arranged menus of thetouch screen display. All settings are visible ata single glance, thus saving time, reducingthe risk of mistakes and increasing conven-ience, e.g. when loading the reflector turret,particularly when filter sets are used in sever-al microscopes. Therefore, it is very easy toupgrade and retrofit the Axio Observer.Furthermore, the 6-position reflector turretallows the very fast change of filter sets inthe beam path during the experiment. Theeasy to operate touch screen display caneither be attached to the the microscope orto a docking station. The docking station canbe freely positioned next to the microscopeor the imaging computer for convenient control of the microscope at all times.

Axio Observer is highly flexible and can be matched to each application level, fromroutine to high end. The open system archi-tecture makes it easy to integrate externalcomponents.

For example, the laser port enables the useof a laser for targeted manipulation in FRAPprocedures, uncaging or the targeted dele-tion of cellular structures.

Manipulation tools are a must in modern cellresearch using a microscope. In addition tomechanical manipulators, optical tools suchas laser scan modules, optical tweezers orlaser microdissection are used in cellresearch. This transforms the Axio Observerinto a complete cell research station. Thebasic Cell Observer system – consisting ofstand, AxioVision software and incubationdevices – is upgraded according to the specific task.

You can choose from three stand models,upgradeable according to your specificrequirements, to make your application aseconomical as possible.

Carl Zeiss is a leading international group ofcompanies operating worldwide in the optical and opto-electronic industry. In fiscalyear 2004/05 (ended 30 September) the CarlZeiss Group generated sales totaling EUR2,222 million. The Carl Zeiss Group hasapproximately 11,500 employees, includingabout 3,300 outside Germany.

Text and photos on the internet:www.zeiss.com/micro-press.

Axio Observer Microscope System – the all-rounder for research on living cells

The docking station with the touch screendisplay for flexible control and configura-tion of the Axio Observer

The Axio Observer family of inverted research microscopes from manual to fully motorized

Carl Zeiss: Living Cells

Carl Zeiss MicroImaging, Inc.One Zeiss DriveThornwood, NY 105941-800-233-2343micro@zeiss.comwww.zeiss.com/micro

8.5x11 2/14/07 2:46 PM Page 1

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F rom a to α is a short supplemental textbook that usescontrol of yeast mating type as a model for many

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� Faculty POSITIONS

Program in Developmental Neuroscience Child Health Institute of New Jersey

The newly established Child Health Institute of New Jersey (CHINJ) at the Robert Wood Johnson Medical

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opportunity/affirmative action employer.