fy2020 adopted international joint research projectscomparative analysis of antibody responses in...

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Adoption year ID№ Principal Investigator PI's Institution Project Title IMSUT Host Researcher 2020 K1006 He Haiping The Affiliated Hospital of Kunming University of Science and Technology The study of immunological activation mechanism of umbilical cord-derived mesenchymal stromal cells Tokiko Nagamura 2020 K1007 Jacques-Olivier Coq Institut de Neurosciences de la Timone, UMR7289 CNRS/Aix- Marseille Univ. Mesenchymal Stromal Cell Therapy to Prevent Neurodevelopmental Disorders related to Low- Birth-Weight Tokiko Nagamura 2020 K1008 Lars Eckmann Department of Medicine, University of California San Diego Novel therapy of intestinal inflammation/infection by targeting mucosal interface Yoshihiro Hirata 2020 K1009 Nikhil Munshi Dana-Farber Cancer Institute, Harvard Medical School Collaborative Translational Research of novel HLA-A24 restrictive investigational cancer vaccine PVX-024 for multiple myeloma Hiroshi Yasui Adoption year ID№ Principal Investigator PI's Institution Project Title IMSUT Host Researcher 2020 K2009 Monica L Acosta The University of Auckland Microglia crosstalk: novel molecular markers to diagnose diabetes-induced eye damage Sumiko Watanabe 2020 K2010 Estelle Duprez Centre de Recherche en Cancérologie de Marseille (CRCM), Institut-Paoli Calmettes (IPC), U1068 INSERM Molecular signature of hematopoietic aging Atsushi Iwama 2020 K2011 Hyeseong Cho Ajou University School of Medicine Molecular mechanisms underlying eukaryotic chromosome segregation Makoto Nakanishi 2020 K2012 Xiao-dong He Cheeloo College of Medicine, Shandong University Study on gene regulation and histone lactating in cancer Makoto Nakanishi 2020 K2013 Bruce Conklin UCSF, Gladstone Institute Establishment of a platform for development and evaluation of exon skipping based gene therapy tool by using human iPS cell Sumiko Watanabe 2020 K2103 Teh Bin Tean National Cancer Centre of Singapore Exploration of novel carcinogenesis processes by elucidating genomic signatures in Asian cancers Tatsuhiro Shibata 2020 K2104 Ro-Ting Lin China Medical University Uterine fibroids: analyzing genetic/epigenetic effect and mediation effect of reproductive function and environmental determinants in Taiwanese and Japanese population Seiya Imoto Adoption year ID№ Principal Investigator PI's Institution Project Title IMSUT Host Researcher 2020 K3011 Florent Ginhoux Singapore Immunology Network (SIgN), A*STAR Investigating Putative Dendritic Cell Precursors (pre-DC) with Neutrophil Progenitor Properties Kenta Nakai 2020 K3012 Catherine Tsai University of Auckland Development of M2e-based intranasal universal influenza vaccine utilizing PilVax platform Kohtaro Fujihashi FY2020 Adopted International Joint Research Projects New Projects (16 Projects) (1) Joint Research Area: Development of Cutting Edge Medical Therapies (4 Projects) (2) Joint Research Area: Genome/Cancer/Disease Systems Biology (7 Projects) (3) Joint Research Area: Infectious Diseases and Immunology (5 Projects)

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Page 1: FY2020 Adopted International Joint Research ProjectsComparative analysis of antibody responses in iEvac-Z-vaccinated subjects and Ebola virus-infected individuals Yoshihiro Kawaoka

Adoptionyear

ID№ Principal Investigator PI's Institution Project Title IMSUT Host Researcher

2020 K1006 He HaipingThe Affiliated Hospital of KunmingUniversity of Science andTechnology

The study of immunological activationmechanism of umbilical cord-derivedmesenchymal stromal cells

Tokiko Nagamura

2020 K1007 Jacques-Olivier CoqInstitut de Neurosciences de laTimone, UMR7289 CNRS/Aix-Marseille Univ.

Mesenchymal Stromal Cell Therapy to PreventNeurodevelopmental Disorders related to Low-Birth-Weight

Tokiko Nagamura

2020 K1008 Lars EckmannDepartment of Medicine, Universityof California San Diego

Novel therapy of intestinalinflammation/infection by targeting mucosalinterface

Yoshihiro Hirata

2020 K1009 Nikhil MunshiDana-Farber Cancer Institute,Harvard Medical School

Collaborative Translational Research of novelHLA-A24 restrictive investigational cancervaccine PVX-024 for multiple myeloma

Hiroshi Yasui

Adoptionyear

ID№ Principal Investigator PI's Institution Project Title IMSUT Host Researcher

2020 K2009 Monica L Acosta The University of AucklandMicroglia crosstalk: novel molecular markers todiagnose diabetes-induced eye damage

Sumiko Watanabe

2020 K2010 Estelle Duprez

Centre de Recherche enCancérologie de Marseille (CRCM),Institut-Paoli Calmettes (IPC),U1068 INSERM

Molecular signature of hematopoietic aging Atsushi Iwama

2020 K2011 Hyeseong Cho Ajou University School of MedicineMolecular mechanisms underlying eukaryoticchromosome segregation

Makoto Nakanishi

2020 K2012 Xiao-dong HeCheeloo College of Medicine,Shandong University

Study on gene regulation and histone lactatingin cancer

Makoto Nakanishi

2020 K2013 Bruce Conklin UCSF, Gladstone InstituteEstablishment of a platform for developmentand evaluation of exon skipping based genetherapy tool by using human iPS cell

Sumiko Watanabe

2020 K2103 Teh Bin TeanNational Cancer Centre ofSingapore

Exploration of novel carcinogenesis processesby elucidating genomic signatures in Asiancancers

Tatsuhiro Shibata

2020 K2104 Ro-Ting Lin China Medical University

Uterine fibroids: analyzing genetic/epigeneticeffect and mediation effect of reproductivefunction and environmental determinants inTaiwanese and Japanese population

Seiya Imoto

Adoptionyear

ID№ Principal Investigator PI's Institution Project Title IMSUT Host Researcher

2020 K3011 Florent GinhouxSingapore Immunology Network(SIgN), A*STAR

Investigating Putative Dendritic Cell Precursors(pre-DC) with Neutrophil Progenitor Properties

Kenta Nakai

2020 K3012 Catherine Tsai University of AucklandDevelopment of M2e-based intranasal universalinfluenza vaccine utilizing PilVax platform

Kohtaro Fujihashi

FY2020 Adopted International Joint Research Projects

New Projects (16 Projects)

(1) Joint Research Area: Development of Cutting Edge Medical Therapies (4 Projects)

(2) Joint Research Area: Genome/Cancer/Disease Systems Biology (7 Projects)

(3) Joint Research Area: Infectious Diseases and Immunology (5 Projects)

Page 2: FY2020 Adopted International Joint Research ProjectsComparative analysis of antibody responses in iEvac-Z-vaccinated subjects and Ebola virus-infected individuals Yoshihiro Kawaoka

2020 K3013 Gabriele Neumann Influenza Research InstituteDevelopment of universal vaccines againstseasonal influenza

Yoshihiro Kawaoka

2020 K3014 Alhaji N’jaiDepartment of Biological SciencesFourah Bay College

Comparative analysis of antibody responses iniEvac-Z-vaccinated subjects and Ebola virus-infected individuals

Yoshihiro Kawaoka

2020 K3015 Jane MegidUniversidade Estadual PaulistaJulio de MesquitaFilho (UNESP)

Surveillance of viruses causing zoonoticinfections in Brazil

Yoshihiro Kawaoka

Page 3: FY2020 Adopted International Joint Research ProjectsComparative analysis of antibody responses in iEvac-Z-vaccinated subjects and Ebola virus-infected individuals Yoshihiro Kawaoka

Adoptionyear

ID№ Principal Investigator PI's Institution Project TitleIMSUT HostResearcher

2019 K1001 Yusheng Cheng Sun Yat-sen UniversityNew treatment strategy in acute on chronic liverfailure using iPS cell derived liver organoids

Hideki Taniguchi

2019 K1002 Joydeep Bhadury Stanford UniversityChimera formation assay with cynomolgusmonkey embryos in vitro

Hiromitsu Nakauchi

2019 K1004 Catherine M. BollardCenter for Cancer & Immunology,Children's National Medical Center

Clinical development of cord blood derivedvirus-specific T cell therapy for cord bloodtransplant recipients in Japan

Satoshi Takahashi

2019 K1005 Jonas LarssonLund Stem Cell Center, LundUniversity

Development of innovative culture method forhematopoietic stem cell expansion

Atsushi Iwama

Adoptionyear

ID№ Principal Investigator PI's Institution Project TitleIMSUT HostResearcher

2019 K2001 Heinrich Leonhardt University of Munich Regulation and Function of DNA methylation Makoto Nakanishi

2019 K2004 Zhihai Qin Institute of Biophysics, CASLigustilide inhibits the promotion effect ofprostate-cancer associated fibroblasts (CAFS)on endothelial cells

Yasushi Kawaguchi

2019 K2005Alejandro Soto-Gutierrez

University of Pittsburgh School ofMedicine

Generation of iPS-derived human hepatocytesin rat liver

Tomoji Mashimo

2019 K2006 Watcharin Loilome Khon Kaen UniversityEstablishment of drug testing system for aprecision medicine in cholangiocarcinoma

Yoshinori Murakami

2019 K2007 Omar Abdel-WahabMemorial Sloan Kettering CancerCenter

Analysis of plethora of ASXL functions underphysiological and pathological conditions

Toshio Kitamura

2019 K2102Martha Espinosa-Cantellano

Center for Research and AdvancedStudies

Multiple sclerosis: analysis of the T and B cellreceptor repertoire in Mexican patients

Seiya Imoto

Adoptionyear

ID№ Principal Investigator PI's Institution Project TitleIMSUT HostResearcher

2019 K3001 Eicke LatzInstitut für Angeborene ImmunitätUniversitätsklinik Bonn,Universität Bonn

Studying roles of Toll-like receptor 9 inautoimmune diseases

Kensuke Miyake

2019 K3002 Peter B. Ernst University of California, San DiegoIntratissue cohabitation of commensal bacteriafor immunity and symbiosis

Kohtaro Fujihashi

2019 K3003 Robert GiffordMRC-University of Glasgow Centrefor Virus Research

Impact of human endogenous retroviruses onvirus infections, human diseases, and evolution

Kei Sato

2019 K3005 Xiyun YanInstitute of Biophysics, ChineseAcademy of Sciences (CAS)

A nanocaged nanobody display platform forinfectious diseases detection and therapy

Yasushi Kawaguchi

FY2020 Adopted International Joint Research Projyects

Extension Projects (18 Projects)

(1) Joint Research Area: Development of Cutting Edge Medical Therapies (4 Projects)

(2) Joint Research Area: Genome/Cancer/Disease Systems Biology (6 Projects)

(3) Joint Research Area: Infectious Diseases and Immunology (8 Projects)

Page 4: FY2020 Adopted International Joint Research ProjectsComparative analysis of antibody responses in iEvac-Z-vaccinated subjects and Ebola virus-infected individuals Yoshihiro Kawaoka

2019 K3006 Kaixia MiInstitute of Microbiology, ChineseAcademy of Sciences (CAS)

Establishment of a model system of co-infection of Mycobacterium and HIV in humanmonocyte cell lines to study their interactions

Yasushi Kawaguchi

2019 K3008 Hualan ChenHarbin Veterinary ResearchInstitute (HVRI), Chinese Academyof Agricultural Sciences (CAAS)

Analysis of the spread and transmissibility ofhighly pathogenic avian influenza H7N9 virusesexhaled from ferrets

Yoshihiro Kawaoka

2019 K3009Anna Katharina (Katja)Simon

Kennedy Institute of Rheumatology,Oxford University

Elucidation of mechanisms involved in tissuespecific immunity during infection

Cevayir Coban

2019 K3010 Peter KatsikisDepartment of Immunology,Erasmus MC, University MedicalCenter Rotterdam

Systems Immunology of human vaccine andimmunotherapy

Ken Ishii