funding and grantsmanship for comparative effectiveness and patient-centered...

Funding and Funding and GrantsmanshipGrantsmanship for Comparative Effectivenessfor Comparative Effectiveness and Patientand Patient--Centered Outcomes Centered Outcomes

ResearchResearch

Jaime S. Rubin, Ph.D.Jaime S. Rubin, Ph.D.Dept. of MedicineDept. of Medicine

College of Physicians and SurgeonsCollege of Physicians and SurgeonsColumbia UniversityColumbia [email protected]@columbia.edu

342342--31843184

mailto:[email protected]

Funding AgenciesFunding Agencies

FederalFederal

National Institutes of Health, Agency for Healthcare Research National Institutes of Health, Agency for Healthcare Research and Qualityand Quality

Voluntary Health Organizations, Professional Societies, Voluntary Health Organizations, Professional Societies, Foundations, IndustryFoundations, Industry

Types of AwardsTypes of Awards

Grants, Contracts, Cooperative agreements,Grants, Contracts, Cooperative agreements,

e.g. Research grants, fellowships, career development awardse.g. Research grants, fellowships, career development awards

Funding AnnouncementsFunding Announcements

Identifying Sources of SupportIdentifying Sources of Support

GrantsmanshipGrantsmanship

Helpful HintsHelpful Hints

Topics to be DiscussedTopics to be Discussed

U.S. Dept. of Health and Human ServicesU.S. Dept. of Health and Human Services

Adapted from: NIH (DRG) Adapted from: NIH (DRG) --

Peer Review of NIH Research Grants ApplicationsPeer Review of NIH Research Grants Applications

Food andDrug

Administration

Centers forDisease Controland Prevention

Substance Abuseand

Mental HealthServices

Administration

NationalInstitutesof Health

Health Resourcesand Services

Administration

Agency for Healthcare Research

AndQuality

Agency forToxic Substances

andDisease Registry

Centers for Medicare &

Medicaid Services

Agency for Healthcare Research and Agency for Healthcare Research and Quality (AHRQ)Quality (AHRQ)

Supports research designed to improve the Supports research designed to improve the quality, safety, efficiency, and effectiveness of quality, safety, efficiency, and effectiveness of health care. health care.

Comparative EffectivenessComparative EffectivenessPrevention and Care ManagementPrevention and Care ManagementValueValueHealth Information TechnologyHealth Information TechnologyPatient SafetyPatient Safety Innovations/Emerging IssuesInnovations/Emerging Issues

AHRQ: AHRQ: Comparative EffectivenessComparative Effectiveness

Comparing treatment optionsComparing treatment options

for different health for different health conditionsconditions

Improve health care qualityImprove health care quality

by providing patients by providing patients and physicians with stateand physicians with state--ofof--thethe--science science information on which medical treatments work information on which medical treatments work best for a given condition. best for a given condition.

Provides comparisonsProvides comparisons

of drugs, medical devices, of drugs, medical devices, tests, surgeries, or ways to deliver health care so tests, surgeries, or ways to deliver health care so that patients and their families understand what that patients and their families understand what treatments work best and how their risks treatments work best and how their risks compare.compare.

National Institutes of HealthNational Institutes of Health



NationalInstituteon Aging

National Instof Allergy &

InfectiousDiseases

National Instof AlcoholAbuse &

Alcoholism

NationalCancerInstitute

NationalEye

Institute

National Heart,Lung,

& Blood Institute

National HumanGenome

Research Inst

National Inst of Arthritis &

Musculoskeletal &Skin Diseases

National Instituteof Child Health

& Human Development

National Inst on Deafness & otherCommunication

Disorders

National Instof Dental &Craniofacial

Research

National Instituteof Diabetes &Digestive &

Kidney Diseases

NationalInstituteon DrugAbuse

NationalInstitute of

EnvironmentalHealth Sciences


GeneralMedical Sciences


Mental Health

National Inst ofNeurological

Dis and Stroke


Nursing Research

NationalLibrary

of Medicine

National Ctr forComplementary & Alt Medicine

John E. FogartyInternational

Center

Officeof the

Director

Center for ScientificReview

Center forInformationTechnology

NIHClinicalCenter

National Inst of Biomedical

Imaging andBioengineering

National Inst on Minority Health & Health Disparities

National Ctr Adv Translational

Sciences


FederalFederal











NIH Extramural ProgramNIH Extramural Program



Mechanism NIH RoleGrant Patron

(Assistance, encouragement)

Cooperative PartnerAgreement (Assistance but substantial

program involvement)

Contract Purchaser(Procurement)


Research grantsResearch grants

Career development Career development awardsawards

Training grantsTraining grants

Individual fellowshipsIndividual fellowships

Career transition Career transition awardsawards

Cooperative Cooperative agreementsagreements

Administrative Administrative supplementssupplements

Institutional Clinical & Institutional Clinical & Translational Science Translational Science Award (CTSA)Award (CTSA)

ContractsContracts

Loan Repayment Loan Repayment ProgramProgram

Not All Funding OpportunitiesNot All Funding Opportunities are the Sameare the Same

Different mission statementsDifferent mission statements

Career development (Career development (KK’’ss))

Research project (RResearch project (R’’s)s)

Different fundingDifferent funding

Stipend/SalaryStipend/Salary

Comprehensive research costsComprehensive research costs

Different time framesDifferent time frames

Not renewable: 5 years (Not renewable: 5 years (KK’’ss), 3 years (F), 3 years (F’’s), 2 years (Ts), 2 years (T’’s)s)

Renewable: 4yearsRenewable: 4years--5years (R01) each competitive period5years (R01) each competitive period


Research ProjectsResearch Projects

(Traditional R01)(Traditional R01)

To support a discrete, specified project To support a discrete, specified project related to the principal investigator's interests related to the principal investigator's interests and competence. Most of the research that and competence. Most of the research that NIH supports is through this funding NIH supports is through this funding mechanism.mechanism.

Research Project Grants: Applications, Research Project Grants: Applications, Awards, and Success RatesAwards, and Success Rates

Research Career Programs (K)Research Career Programs (K)

Provides predominantly salary supportProvides predominantly salary support

Specified salary levels Specified salary levels (e.g. NIDDK: $90K, NCI: $100K)(e.g. NIDDK: $90K, NCI: $100K)

Minimum Minimum efffortefffort: e.g. 75%, (some exceptions to 50%) : e.g. 75%, (some exceptions to 50%) Research and Career Development activities Research and Career Development activities

Up to 5 yearsUp to 5 years

US citizen/permanent residentUS citizen/permanent resident

Reduce effort to 50% in last 2 years if PI of NIH Reduce effort to 50% in last 2 years if PI of NIH research grantresearch grant

K08/K23 R01

K23K12

K12 R01

K12 K23

R01

R01

K08/K23 R01

Career Development (K) SupportCareer Development (K) Support to Research Grant (R01)to Research Grant (R01)

Mentored Clinical Scientist Mentored Clinical Scientist Development Award Development Award (K08)(K08)

Support to develop outstanding Support to develop outstanding independent clinician research scientistsindependent clinician research scientists

Basic and translational scienceBasic and translational science

Mentored PatientMentored Patient--Oriented ResearchOriented Research

Career Development Award Career Development Award (K23)(K23)

For investigators just after specialty training; not For investigators just after specialty training; not renewable; renewable;

MidMid--Career Investigator In PatientCareer Investigator In Patient--Oriented Oriented Research Career Development Award Research Career Development Award (K24)(K24)

Support for clinicians to allow for time to devote to Support for clinicians to allow for time to devote to patientpatient--oriented research and to mentor beginning oriented research and to mentor beginning clinical investigators;clinical investigators;

PatientPatient--oriented research:oriented research:

Research conducted with human subjects Research conducted with human subjects (or on material of human origin, i.e. tissues, (or on material of human origin, i.e. tissues, specimens, and cognitive phenomena)specimens, and cognitive phenomena)

Investigator directly interacts with human Investigator directly interacts with human subjectssubjects

Research areas:Research areas:

(1)(1)

Mechanisms of human diseaseMechanisms of human disease(2)(2)

Therapeutic interventionsTherapeutic interventions

(3)(3)

Clinical trialsClinical trials(4)(4)

Development of new technologiesDevelopment of new technologies

Mentored Research Scientist Mentored Research Scientist Development Award (K01)Development Award (K01)

Not all NIH Institutes participate in programNot all NIH Institutes participate in programParticipating Institutes may use for different Participating Institutes may use for different

purposespurposes

Train in a new fieldTrain in a new field

Specific research areasSpecific research areas

Hiatus in research careerHiatus in research career

Increase research workforce diversityIncrease research workforce diversity

Mentored Research ScientistMentored Research ScientistDevelopment Awards (K01)Development Awards (K01)

National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases (NIAID(NIAID::

Outcomes ResearchOutcomes Research

National Heart, Lung, and Blood Institute National Heart, Lung, and Blood Institute (NHLBI)(NHLBI): :

Comparative Effectiveness Research Comparative Effectiveness Research

Research Career Development AwardsResearch Career Development Awards

AHRQ K08: Mentored Clinical Scientist AHRQ K08: Mentored Clinical Scientist Research Career Development AwardResearch Career Development Award

Quality, Quality,

Safety, Safety,

Efficiency, and Efficiency, and

Effectiveness of Health CareEffectiveness of Health Care

AHRQ K18: Mentored Career Enhancement AHRQ K18: Mentored Career Enhancement Award in Patient Centered Outcomes Research Award in Patient Centered Outcomes Research for Midfor Mid--Career and Senior InvestigatorsCareer and Senior Investigators

To prepare candidates to be independent investigators in To prepare candidates to be independent investigators in PatientPatient--Centered Outcomes Research (PCOR), by Centered Outcomes Research (PCOR), by providing them the methodological skills required for providing them the methodological skills required for comparative effectiveness research (CER)comparative effectiveness research (CER)


FederalFederal











NonNon--government agency, Created in 2010government agency, Created in 2010

http://www.pcori.org/http://www.pcori.org/

National Priorities for Research and Research National Priorities for Research and Research AgendaAgenda

HighHigh--impact patientimpact patient--centered outcomes researchcentered outcomes research

PFA: PCORI Funding AnnouncementsPFA: PCORI Funding Announcements

Accelerated Process to Targeted Accelerated Process to Targeted PFAsPFAs

“…“…questions solicited directly from patients and other questions solicited directly from patients and other stakeholders through our website, workshops, and stakeholders through our website, workshops, and roundtablesroundtables…”…”

PatientPatient--Centered Outcomes Centered Outcomes Research Institute (PCORI)Research Institute (PCORI)

http://www.pcori.org/

1. 1. Assessment of Prevention, Diagnosis, and Assessment of Prevention, Diagnosis, and Treatment OptionsTreatment Options

--

Projects that address critical Projects that address critical

decisions that patients, their caregivers and decisions that patients, their caregivers and clinicians face with too little informationclinicians face with too little information

2. 2. Improving Healthcare SystemsImproving Healthcare Systems

--

Projects that Projects that

address critical decisions that face health care address critical decisions that face health care systems, the patients and caregivers who rely on systems, the patients and caregivers who rely on them, and the clinicians who work within themthem, and the clinicians who work within them

PCORI: National Priorities for PCORI: National Priorities for Research and Research AgendaResearch and Research Agenda

3. 3. Communication and Dissemination ResearchCommunication and Dissemination Research

--

Projects that address critical elements in the Projects that address critical elements in the communication and dissemination process among communication and dissemination process among patients, their caregivers and clinicianspatients, their caregivers and clinicians

4. 4. Addressing DisparitiesAddressing Disparities

--

Projects that will inform Projects that will inform

the choice of strategies to eliminate disparitiesthe choice of strategies to eliminate disparities

5. 5. Accelerating PatientAccelerating Patient--Centered Outcomes Centered Outcomes Research and Methodological ResearchResearch and Methodological Research

--

Projects to Projects to

improve the nationimprove the nation’’s underlying capacity to conduct s underlying capacity to conduct patientpatient--centered outcomes research rapidly, centered outcomes research rapidly, efficiently and consistently over timeefficiently and consistently over time

Treatment Options for Uterine FibroidsTreatment Options for Uterine Fibroids

Treatment Options for Severe Asthma in AfricanTreatment Options for Severe Asthma in African--

Americans and Hispanics/LatinosAmericans and Hispanics/Latinos

Preventing Injuries from Falls in the ElderlyPreventing Injuries from Falls in the Elderly

Treatment Options for Back PainTreatment Options for Back Pain

Obesity Treatment Options in Diverse PopulationsObesity Treatment Options in Diverse Populations

PCORI: Accelerated ProcessPCORI: Accelerated Process to Targeted to Targeted PFAsPFAs

Mentored Clinical and Population Research Award Mentored Clinical and Population Research Award

Early career investigatorsEarly career investigators

Proposals are encouraged on Proposals are encouraged on “…“…behavioral outcomes, behavioral outcomes, risk factor outcomes, disease outcomes, cost benefit risk factor outcomes, disease outcomes, cost benefit analyses, efforts to evaluate outcomes of patient care analyses, efforts to evaluate outcomes of patient care deliverydelivery…”…”

Founders Affiliate: $75,000/year for two yearsFounders Affiliate: $75,000/year for two years

National: $77,000/year for two yearsNational: $77,000/year for two years

American Heart AssociationAmerican Heart Association

PhRMAPhRMA

FoundationFoundation

“…“…owes its success to the pharmaceutical companies owes its success to the pharmaceutical companies that have provided their generous supportthat have provided their generous support…”…”

“…“…to support young scientists in disciplines to support young scientists in disciplines important to the pharmaceutical industry by awarding important to the pharmaceutical industry by awarding them competitive research fellowships and grantsthem competitive research fellowships and grants…”…”

http://www.phrmafoundation.org/http://www.phrmafoundation.org/

Adherence, Adherence, Health OutcomesHealth Outcomes, Informatics, , Informatics, Pharmacology/ Toxicology, Pharmaceutics, Pharmacology/ Toxicology, Pharmaceutics, PharmaceuticsPharmaceutics

http://www.phrmafoundation.org/

PhRMAPhRMA

Foundation Foundation --

Health OutcomesHealth Outcomes

Burden of DiseaseBurden of DiseaseComparative EffectivenessComparative Effectiveness

AnalysisAnalysisCompliance/AdherenceCompliance/AdherenceCost Consequences AnalysisCost Consequences AnalysisCostCost--Benefit AnalysisBenefit AnalysisCostCost--Effectiveness AnalysisEffectiveness AnalysisCost Utility AnalysisCost Utility AnalysisHealth Outcomes ResearchHealth Outcomes ResearchHealth Related Quality of LifeHealth Related Quality of Life

Health Services ResearchHealth Services ResearchPatient SatisfactionPatient SatisfactionPatient PreferencesPatient PreferencesPharmacoeconomicsPharmacoeconomicsPatient Reported OutcomesPatient Reported OutcomesPsychometric Evaluation of Psychometric Evaluation of

Questionnaires Research Questionnaires Research MethodsMethods

Symptom MeasuresSymptom MeasuresTolerability Tolerability

PhRMAPhRMA



PrePre--Doctoral FellowshipsDoctoral Fellowships

Advanced Ph.D. candidates, stipend of $25,000 per Advanced Ph.D. candidates, stipend of $25,000 per year for a maximum of two yearsyear for a maximum of two years

PostPost--Doctoral FellowshipsDoctoral Fellowships

$55,000 annual stipend (for up to 2 years) to $55,000 annual stipend (for up to 2 years) to graduates of from graduates of from PharmDPharmD., M.D., and Ph.D. ., M.D., and Ph.D. programsprograms

PhRMAPhRMA



Research Starter GrantsResearch Starter Grants

Instructor or assistant professor (or equivalent)Instructor or assistant professor (or equivalent)

Funding for salary, technical assistance, equipment, Funding for salary, technical assistance, equipment, and travel and travel

Sabbatical FellowshipsSabbatical Fellowships

$40,000 stipend (6 mo$40,000 stipend (6 mo--1 yr) for mid1 yr) for mid--career scientists career scientists to learn new skills and develop new collaborations to learn new skills and develop new collaborations in health outcomes research and trainingin health outcomes research and training


FederalFederal











NIH/AHRQNIH/AHRQ Funding AnnouncementsFunding Announcements

http://www.niaid.nih.gov/ncn/grants/cycle/part02.htm

Funding Opportunity Announcement Funding Opportunity Announcement (FOA)(FOA)

FOA MechanismFOA Mechanism

Published in the Published in the NIH Guide for Grants and NIH Guide for Grants and ContractsContracts

((RFAsRFAs, , PAsPAs))

and and Grants.govGrants.gov

http://http://grants.nih.gov/grants/guide/index.htmlgrants.nih.gov/grants/guide/index.html

Grants.govGrants.gov

notice includes application information notice includes application information and formsand forms

http://grants1.nih.gov/grants/guide/index.html


http://grants.gov/

http://grants.gov/

Parent AnnouncementParent Announcement

Funding Opportunity AnnouncementFunding Opportunity Announcement

for for

unsolicited investigatorunsolicited investigator--initiated grantinitiated grant

applications applications (e.g. R01)(e.g. R01)

Allows electronic submission of grant applications that Allows electronic submission of grant applications that are not in response to specific Program Announcement are not in response to specific Program Announcement or RFA.or RFA.

Published in the Published in the NIH Guide for Grants and ContractsNIH Guide for Grants and Contracts



notice includes application information and notice includes application information and formsforms

http://http://grants.nih.gov/grants/guide/parent_announcements.htmgrants.nih.gov/grants/guide/parent_announcements.htm


http://grants.gov/

http://grants.gov/

http://grants.nih.gov/grants/guide/parent_announcements.htm

http://grants.nih.gov/grants/guide/parent_announcements.htm

Program Announcement (PA)Program Announcement (PA)

No setNo set--aside of fundsaside of funds

Describes existence of an NIH extramural Describes existence of an NIH extramural research programresearch program

May describe new or expanded interest in a May describe new or expanded interest in a particular extramural programparticular extramural program

May be a reminder of a continuing interest in May be a reminder of a continuing interest in an extramural programan extramural program

Applications reviewed at Center for Scientific Applications reviewed at Center for Scientific Review (CSR) not the InstituteReview (CSR) not the Institute

Published in the Published in the NIH Guide for Grants and NIH Guide for Grants and ContractsContracts


Adapted from: NIH (DRG) - Peer Review of NIH Research Grants Applications



http://grants.gov/

Program Announcement (PAR)Program Announcement (PAR)

PAR MechanismPAR Mechanism

Grant applications are Grant applications are reviewedreviewed

at the Institute and not at the Institute and not the Center for Scientific Review (CSR)the Center for Scientific Review (CSR)

Usually some applications are fundedUsually some applications are funded

Program Announcement (PAS)Program Announcement (PAS)

PAS MechanismPAS Mechanism

Program Announcement with dedicated fundingProgram Announcement with dedicated funding

““Set aside fundsSet aside funds””

Funds applications that may receive a score below Funds applications that may receive a score below the the paylinepayline

Research area coincides with programmatic interests Research area coincides with programmatic interests of Instituteof Institute

Funds allocated throughout duration of the PASFunds allocated throughout duration of the PAS

Request For Applications (RFA)Request For Applications (RFA)

Formal announcement describing an institute Formal announcement describing an institute initiative in a initiative in a wellwell--defined scientific areadefined scientific area

Invitation to the field to submit Invitation to the field to submit research grant or research grant or cooperative agreementcooperative agreement

applications for a oneapplications for a one--time time

competitioncompetition

SetSet--aside of fundsaside of funds

for a certain number of awardsfor a certain number of awards

Published in the Published in the NIH Guide for Grants and ContractsNIH Guide for Grants and Contracts



http://grants.gov/

Request For Proposals (RFP)Request For Proposals (RFP)

Formal announcement describing an institute Formal announcement describing an institute initiative in a initiative in a wellwell--defined scientific areadefined scientific area

Invitation to the field to submit Invitation to the field to submit contractcontract

applications for a oneapplications for a one--time competitiontime competition

SetSet--aside of fundsaside of funds

for a certain number of awardsfor a certain number of awards

Published in Published in FedBizOppsFedBizOpps

http://www.fbo.gov/


Research on Comparative Effectiveness and Research on Comparative Effectiveness and Implementation of HIV/AIDS and Alcohol Implementation of HIV/AIDS and Alcohol InterventionsInterventions

(NIAAA) (deadline: May 29, 2013)(NIAAA) (deadline: May 29, 2013)

R01: RFAR01: RFA--AAAA--1313--003, 4 awards, $2.5 million in total costs 003, 4 awards, $2.5 million in total costs for fiscal year 2013for fiscal year 2013

R21: RFAR21: RFA--AAAA--1313--004, 2004, 2--3 awards, $0.5 million in total costs3 awards, $0.5 million in total costs for fiscal year 2013for fiscal year 2013


International Traumatic Brain Injury Research International Traumatic Brain Injury Research Initiative: NIH Cooperative Program for Comparative Initiative: NIH Cooperative Program for Comparative Effectiveness of Clinical Tools and TherapiesEffectiveness of Clinical Tools and Therapies

(U01) (U01)

RFARFA--NSNS--1313--008008

Deadline: April 1, 2013 Deadline: April 1, 2013

Neurological Disorders and Stroke (NINDS)Neurological Disorders and Stroke (NINDS)

$3.3 million to support co$3.3 million to support co--funding of 1 award (FY2013)funding of 1 award (FY2013)

Biomedical Imaging and Bioengineering (NIBIB)Biomedical Imaging and Bioengineering (NIBIB)

$250,000 to support co$250,000 to support co--funding of 1 award (FY2013)funding of 1 award (FY2013)

Deafness and Other Communication Disorders (NIDCD)Deafness and Other Communication Disorders (NIDCD)

$200,000 to support co$200,000 to support co--funding of 1 award (FY2013)funding of 1 award (FY2013)

Program Announcement (PA)Program Announcement (PA)

Disorders of Human Communication: Effectiveness, Disorders of Human Communication: Effectiveness, Outcomes and Health Services ResearchOutcomes and Health Services Research

National Institute on Deafness and Other Communication National Institute on Deafness and Other Communication Disorders (NIDCD) Disorders (NIDCD)

R01: PAR01: PA--1313--102 102

R21: PAR21: PA--1313--103103

Application Due Application Due Date(sDate(s): Standard dates): Standard dates

The number of awards is contingent upon NIH The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of appropriations and the submission of a sufficient number of meritorious applicationsmeritorious applications


FederalFederal











How to Find Funding OpportunitiesHow to Find Funding Opportunities

NetworkingNetworking

Speak to colleagues who are in a similar fieldSpeak to colleagues who are in a similar field

Speak to colleagues who have been on Speak to colleagues who have been on governmental or private agency review panelsgovernmental or private agency review panels

Speak to colleagues who are on (advisory) Speak to colleagues who are on (advisory) boards of private agencies boards of private agencies

Web ResourcesWeb Resources

SPIN funding databaseSPIN funding database

https://https://www.infoed.columbia.eduwww.infoed.columbia.edu//

SMARTS eSMARTS e--mail alert modulemail alert module

GrantsNetGrantsNet

Funding database for junior investigatorsFunding database for junior investigators

Funding news eFunding news e--mail alertsmail alerts

http://sciencecareers.sciencemag.org/fundinghttp://sciencecareers.sciencemag.org/funding

National Institutes of HealthNational Institutes of Health

http://http://grantscourse.columbia.edu/nih.htmgrantscourse.columbia.edu/nih.htm

https://www.infoed.columbia.edu/



http://sciencecareers.sciencemag.org/funding

http://grantscourse.columbia.edu/nih.htm

http://grantscourse.columbia.edu/nih.htm


Database and application system for Federal grantsDatabase and application system for Federal grants

http://www.Grants.gov/http://www.Grants.gov/

FedBizOppsFedBizOpps

(Federal Business Opportunities)(Federal Business Opportunities)

Single pointSingle point--ofof--entry for Federal contractsentry for Federal contracts

http://http://www.FedBizOpps.govwww.FedBizOpps.gov//

Tips for Writing Grant ApplicationsTips for Writing Grant Applications

http://http://grantscourse.columbia.edu/writing.htmgrantscourse.columbia.edu/writing.htm

http://www.grants.gov/

http://www.fedbizopps.gov/



http://grantscourse.columbia.edu/writing.htm

http://grantscourse.columbia.edu/writing.htm

Other Sources of InformationOther Sources of Information

Sponsor publications which describe research Sponsor publications which describe research interests (e.g. newsletters, annual reports)interests (e.g. newsletters, annual reports)

Sponsor eSponsor e--mail alert modulesmail alert modules

NIHNIH

““List of ListsList of Lists””: : https://https://list.nih.govlist.nih.gov//

NIH GuideNIH Guide: : https://list.nih.gov/archives/nihtochttps://list.nih.gov/archives/nihtoc--l.htmll.html

““NIAIDNIAID--EMAIL ALERTSEMAIL ALERTS””

Profile: Profile: http://visitor.constantcontact.com/optin.jsp?edit=t&m=1100850163http://visitor.constantcontact.com/optin.jsp?edit=t&m=1100850163367&t=1101202977468&ea=jsr9%40columbia.edu&lang=en367&t=1101202977468&ea=jsr9%40columbia.edu&lang=en

https://list.nih.gov/archives/nihtoc-l.html




http://visitor.constantcontact.com/optin.jsp?edit=t&m=1100850163367&t=1101202977468&ea=jsr9%40columbia.edu&lang=en

http://visitor.constantcontact.com/optin.jsp?edit=t&m=1100850163367&t=1101202977468&ea=jsr9%40columbia.edu&lang=en

The Foundation CenterThe Foundation Center

The Foundation Directory OnlineThe Foundation Directory OnlineSearchable database (fee) of approx 80,000 Searchable database (fee) of approx 80,000 foundations and their tax statements (990foundations and their tax statements (990’’s)s)Access via Columbia University Access via Columbia University ((““freefree””))

http://www.columbia.edu/cgihttp://www.columbia.edu/cgi--bin/cul/resolve?clio3328966bin/cul/resolve?clio3328966

79 Fifth Avenue (at 16th St.)79 Fifth Avenue (at 16th St.)New York, NY 10003New York, NY 10003--30763076Tel: (212) 620Tel: (212) 620--42304230Fax: (212) 691Fax: (212) 691--1828 1828 http://http://foundationcenter.orgfoundationcenter.org//http://http://foundationcenter.org/newyorkfoundationcenter.org/newyork//

http://www.columbia.edu/cgi-bin/cul/resolve?clio3328966



http://foundationcenter.org/



http://foundationcenter.org/newyork/



SPINSPINSponsored Programs Information NetworkSponsored Programs Information Network

Database of funding opportunities

National and international government and private funding agencies

Research grants, fellowships, career development, etc.

Searchable fields

Keywords

Applicant type (e.g. Postdoctoral, Young Investigator)

Award Types (e.g. Equipment, Fellowship)

Sponsor Type (e.g. Foundations, Voluntary Health Organization)

SPINSPINSponsored Programs Information NetworkSponsored Programs Information Network

http://spa.columbia.edu/funding/search-funding-spin

SMARTSSMARTSSPIN Matching and Research Transmittal ServiceSPIN Matching and Research Transmittal Service

Automated daily eAutomated daily e--mail alert systemmail alert system

Reports of relevant funding opportunities from Reports of relevant funding opportunities from SPIN database based on investigatorSPIN database based on investigator--selected selected keywordskeywords

http://spa.columbia.edu/funding/search-funding-spin

http://projectreporter.nih.gov/reporter.cfm

NIH NIH RePORTERRePORTER: Grants Database: Grants Database

http://projectreporter.nih.gov/reporter.cfm

http://report.nih.gov/categorical_spending.aspx

NIH: Funding for Various Research, NIH: Funding for Various Research, Condition, and Disease Categories Condition, and Disease Categories (RCDC)(RCDC)

http://report.nih.gov/categorical_spending.aspx


FederalFederal











When Preparing an Application:When Preparing an Application:

Read instructionsRead instructions

Never assume that reviewers Never assume that reviewers ““will know what will know what you meanyou mean””

Refer to literature thoroughly and Refer to literature thoroughly and thoughtfullythoughtfully

Explicitly state the rationale of the proposed Explicitly state the rationale of the proposed investigationinvestigation

Include wellInclude well--designed tables and figuresdesigned tables and figures

Present an organized, lucid writePresent an organized, lucid write--upup

Elements of a Good ProposalElements of a Good Proposal

FeasibleFeasible

RelevantRelevant

UniqueUnique

InnovativeInnovative

ClearClear

BriefBrief

ConsistentConsistent

Common Problems with Grant Common Problems with Grant Applications from New InvestigatorsApplications from New Investigators

Overly ambitiousOverly ambitious

Not independent of previous mentorNot independent of previous mentor’’s researchs research

Fishing expeditionFishing expedition

Not hypothesis drivenNot hypothesis driven

Descriptive, not mechanistic projectDescriptive, not mechanistic project

UnfocussedUnfocussed

No or insufficient preliminary dataNo or insufficient preliminary data

Unrealistic budgetUnrealistic budget

Methodologies beyond the expertise of investigator Methodologies beyond the expertise of investigator or research teamor research team

Good Luck!Good Luck!

funding and grantsmanship for comparative effectiveness and patient-centered...

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