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Fundic glands

H&E stain of fundic gland polyp showing shortening of the gastric pits with cystic dilatation

Latin glandulae gastricae

Gray's subject #247 1166 (http://education.yahoo.com/reference/gray/subjects/subject?id=247#p1166)

From Wikipedia, the free encyclopedia

The fundus

glands (or

fundic glands,

or gastric

glands) arefound in the

body and fundus

of the stomach.

They are simple

tubes, two or

more of which

open into a

single duct.

1 Pathology

2 Types of cells

3 Additional images

4 External links

Fundic gland polyposis is a medical syndrome where the fundus of the stomach develops many polyps.

Location Name Description Secretion Staining

IsthmusMucous neck

cellsIn gastric pits.

mucus gel

layerClear

c glands - Wikipedia, the free encyclopedia http://en.wikipedia.org/wiki/Fund

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Neckparietal (oxyntic)

cells

Between the chief cells and the basement

membrane, larger oval cells, which stain deeply

with eosin, are found; these cells are studded

throughout the tube at intervals, giving it a beaded

or varicose appearance. These are known as the

parietal cells or oxyntic cells, and they are

connected with the lumen by fine channels which

run into their substance.

gastric acid

and intrinsic

factor

Acidophilic

Base

chief

(zymogenic)

cells

At the point where they open into the duct, which

is termed the neck, the epithelium alters, and

consists of short columnar or polyhedral, granular

cells, which almost fill the tube, so that the lumen

becomes suddenly constricted and is continued

down as a very fine channel. They are known as

the chief cells or central cells of the glands.

pepsinogen,

renninBasophilic

Base enteroendocrine(APUD) cells

G cells are a type of enteroendocrine cell that

secrete the hormone gastrin (gastrin promotes the

secretion of pepsinogen (by chief cells) and HCl

(by parietal cells) and promotes gastric

contractions to mix contents).

hormones -

A fundus gland. A.

Transverse section of

gland.

Layers of stomach wall

gastric+glands (http://www.emedicinehealth.com/script/main/srchcont_dict.asp?src=gastric+glands) at

eMedicine Dictionary

Histology at OU 50_02 (http://w3.ouhsc.edu/histology/Glass%20slides/50_02.jpg) - "Fundic stomach"

Organology at UC DavisDigestive/mammal/stomach4/stomach2 (http://trc.ucdavis.edu/mjguinan/apc100

/modules/Digestive/mammal/stomach4/stomach2.html) - "Mammal, ruminant stomach (LM, High)"

Histology at BU 11301ooa (http://www.bu.edu/histology/p/11301ooa.htm) - "Digestive System:

Alimentary Canal - fundic stomach"


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Veterinary Histology at vt.edu (http://education.vetmed.vt.edu/curriculum/VM8054/Labs/Lab18

/EXAMPLES/Exfndgld.htm)

MedEd at LoyolaHisto/frames/Histo18.html (http://www.meddean.luc.edu/Lumen/MedEd/Histo/frames

/Histo18.html) - see slide #42

This article was originally based on an entry from a public domain edition ofGray's Anatomy. As such, some of

the information contained within it may be outdated.

Retrieved from "http://en.wikipedia.org/w/index.php?title=Fundic_glands&oldid=425628062"

Categories: Digestive system Digestive system stubs

This page was last modified on 24 April 2011 at 07:58.

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