fundamentals of stereotaxy

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    Fundamentals of Stereotaxy

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    What is Stereotaxy?

    Referencing of unknown volume within a coordinate system

    Mathematical Concept that identifies a point in space by itsrelationship to 3 planes intersecting at right angles to each

    other and intersecting at a common point

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    X

    Axes IntroducedFree Volume

    X X

    X

    Imaging Grid

    Quantifies Volume

    Treatment Grid

    Replaces Imaging Grid

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    Axes Introduced

    Free Volume

    X

    X

    Imaging GridTreatment Grid

    X

    Headring = Axis

    Localizer = GridCRW Arc = Treatment Grid

    X

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    Importance of Stereotaxy

    Gives us the ability to reach very specific points in the

    brain that are close to critical structures without creating

    damage to surrounding tissue

    Initial interest for Parkinsons Disease Surgery

    Extended to applications where accuracy is paramount

    biopsy

    functional neurosurgery

    microsurgery

    radiosurgery

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    History of Stereotaxy

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    SPIEGEL WYCIS

    Philadelphia, 1947

    Human Stereotactic Apparatus

    - tactic to touch

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    Other Frames...

    Lars Leksell, Sweden, 1949

    Tallairach, Paris, France 1949

    Riechert & Wolff, Freiburg, Germany 1951

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    Problem with Existing Frames

    No Quality Assurance

    Stab blindly in the dark

    ?

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    BRW

    (Brown-Roberts-Wells)

    USA, 1980

    Interlocking Arcs

    zero centred

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    Quality Assurance

    AP, LAT, VERT

    BRW Phantom Base

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    CRW

    (Cosman-Roberts-Wells)

    USA, 1988

    Arc Centred

    CRW Phantom Base

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    Medical Imaging

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    Role of Medical Imaging

    Increasing interest for Cancer Treatment

    Investigation

    Diagnosis Planning

    Monitoring Treatment of Malignant Diseases

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    X-rays

    Discovery of X-rays:

    Wilhelm Rntgen, Wrzburg, Germany, November

    1895

    1st Clinical Use:

    Needle removed from womans hand using X-rays

    Birmingham, UK January 1896

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    X-rays

    X-rays:

    Projectionof the

    attenuating properties

    of all the tissue along

    the paths of photons

    Patient

    X-ray source

    Receptor

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    Angiography

    X-ray of blood vessels

    radio-opaque dye injected and x-rays taken

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    Computerized Tomography

    Conventional X-rays deficient in recognizing

    Soft tissue

    Depth Information

    Needed Method for Taking X-rays on sections

    of body

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    Computerized Tomography

    Invention: Radon, 1917

    x-ray CT in Clinical Environment:

    Hounsfield, British Institute of Radiology Conference,1972

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    Magnetic Resonance Imaging

    Nuclear Magnetic Resonance (NMR)

    discovered independently by 2 sources in 1946

    Resonance by Magnetic Field Gradient discovered in Lauterbur 1973

    Put Patient in Magnetic Field & take images of

    sections of body

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    Magnetic Resonance Imaging

    Apply Strong Magnetic Field

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    Magnetic Resonance Imaging

    Inject Pulsed Radiofrequency

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    Magnetic Resonance Imaging

    Remove Pulsed Radiofrequency

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    CT vs MR

    CT

    Good for geometric accuracy

    Bad for Morphological DetailMR

    Good for Morphological Detail

    Bad for geometric accuracy - distortion

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    Other Types of Imaging

    SPECT:

    Single Photon Emission Computed Tomography

    Allows us to see functional information on specific

    organs. Inject radioactive isotopes that emit

    gamma rays when decaying; these are shown in

    the images

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    Other Types of Imaging

    fMRI:

    functional Magnetic Resonance Imaging

    Allows us to monitor increase of blood flow.

    Different activity correspond to different levels of

    blood flow. So, monitor the blood flow & you get

    the different areas of brain controlling the various

    functions.

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    Other Types of Imaging

    fMRI

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    Image Guided Surgery

    Horsley & Clarke

    Spiegel & Wycis

    Leksell

    Tallairach

    Riechert & Wolff

    BRW

    CRW

    1908

    1980s

    Xray

    CT

    MR

    PET/SPECT/fMRI

    1876

    1980sComputer Technology

    Image

    GuidedSurgery

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    Image Guided Surgery

    Horsley & Clarke

    Spiegel & Wycis

    Leksell

    Tallairach

    Riechert & Wolff

    BRW

    CRW

    1908

    1980s

    Xray

    CT

    MR

    PET/SPECT/fMRI

    1876

    1980sComputer Technology

    3D Planning

    Accurate Targetting

    Reduce Damage to Healthy Tissue

    More Procedures Operable

    Patient Comfort

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    Image Guided Surgery

    Horsley & Clarke

    Spiegel & Wycis

    Leksell

    Tallairach

    Riechert & Wolff

    BRW

    CRW

    1908

    1980s

    Xray

    CT

    MR

    PET/SPECT/fMRI

    1876

    1980sComputer Technology

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    Uses of Framed Stereotaxy

    Stereotactic

    Radiosurgery/Radiotherapy

    Functional Neurosurgery

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    Parkinsons isease Surgery

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    Parkinsons isease Surgery

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    Frameless Stereotaxy

    Put CT/MR Scans of

    Patient in w/sCo-register Patients

    Head to Scans in w/s

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    Markers Create Volume

    in Image Space

    Skin Markers

    Localizer Quantifies Volume

    in Image Space

    Localizer

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    Markers Create Volume

    in Image Space

    Skin MarkersRegister Patient to Image Space

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    OAS

    (Operating Arm System)

    1992

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    Surgical Product Range...

    StereotaxyHardware/Software for

    Frame Based StereotaxyNeurosurgery/Radiotherapy

    Image GuidedHardware/Software for

    Frameless Stereotaxy