functional organization of the endocrine system $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400...

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Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100 $ 100 $100 $100 $200 $200 $200 $200 $300 $300 $300 $300 $400 $400 $400 $400 $500 $500 $500 $500 Introductio n FINAL ROUND Homeostasis Transport and Metabolism Receptors Grab Bag

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Page 1: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Functional Organization of the Endocrine System

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Introduction

FINAL ROUND

HomeostasisTransport

and Metabolism

ReceptorsGrab Bag

Page 2: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$100 Question

The endocrine system communicates with target cells by way of this:

a. chemical messengers that do not leave the cell where they are produced

b. chemical messengers secreted into the bloodstream

c. chemical messengers secreted through ducts into other organ

d. electrical signals BACK TO GAME

ANSWER

Page 3: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$100 Answer

The endocrine system communicates with target cells by way of this:

a. chemical messengers that do not leave the cell where they are produced

b. chemical messengers secreted into the bloodstream

c. chemical messengers secreted through ducts into other organ

d. electrical signals BACK TO GAME

Page 4: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$200 Question

Given these characteristics: 1. amplitude-modulated signals2. all-or-none response3. usually slower response4. effects usually more generally distributed

List the characteristics that apply to the endocrine system when compared to the nervous system.

a. 2,3 c. 1,3,4

b. 1,2,4 d. 1,2 3,4 BACK TO GAME

ANSWER

Page 5: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$200 Answer

Given these characteristics: 1. amplitude-modulated signals2. all-or-none response3. usually slower response4. effects usually more generally distributed

List the characteristics that apply to the endocrine system when compared to the nervous system.

a. 2,3 c. 1,3,4

b. 1,2,4 d. 1,2 3,4BACK TO GAME

Page 6: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$300 Question

Chemical signals that are secreted into the environment and modify the behavior and physiology of other individuals are called this:

a. autocrine chemical signals

b. pheromones

c. paracrine chemical signals

d. hormones

e. neurotransmitters BACK TO GAME

ANSWER

Page 7: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$300 Answer

Chemical signals that are secreted into the environment and modify the behavior and physiology of other individuals are called this:

a. autocrine chemical signals

b. pheromones

c. paracrine chemical signals

d. hormones

e. neurotransmitters BACK TO GAME

Page 8: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$400 Question

Neurohormones are intercellular chemical signals that do this:

a. produced by groups of cells and affect neurons

b. released by cells and affect other cell types locally

c. produced by neurons and act like hormones

d. released by neurons and stimulate or inhibit other neurons

BACK TO GAME

ANSWER

Page 9: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$400 Answer

Neurohormones are intercellular chemical signals that do this:

a. produced by groups of cells and affect neurons

b. released by cells and affect other cell types locally

c. produced by neurons and act like hormones

d. released by neurons and stimulate or inhibit other neurons BACK TO GAME

Page 10: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$500 Question

Estrogen, progesterone, testosterone, and glucocorticoids are all examples of this:

a. proteins

b. glycoproteins

c. polypeptides

d. amino acid derivatives

e. steroidsBACK TO GAME

ANSWER

Page 11: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Introduction:

$500 Answer

Estrogen, progesterone, testosterone, and glucocorticoids are all examples of this:

a. proteins

b. glycoproteins

c. polypeptides

d. amino acid derivatives

e. steroids

BACK TO GAME

Page 12: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$100 Question

This statement about hormones is true except:

a. are secreted at a constant rate

b. function to regulate the rates of many activities in the body

c. secretion rate is controlled by negative feedback mechanisms

d. help maintain homeostasisBACK TO GAME

ANSWER

Page 13: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$100 Answer

This statement about hormones is true except:

a. are secreted at a constant rate

b. function to regulate the rates of many activities in the body

c. secretion rate is controlled by negative feedback mechanisms

d. help maintain homeostasis

BACK TO GAME

Page 14: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$200 Question

This regulates the secretion of a hormone from an endocrine tissue:

a. other hormones

b. negative-feedback mechanisms

c. nonhormone substance in the blood

d. the nervous system

e. all of the aboveBACK TO GAME

ANSWER

Page 15: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$200 Answer

This regulates the secretion of a hormone from an endocrine tissue:

a. other hormones

b. negative-feedback mechanisms

c. nonhormone substance in the blood

d. the nervous system

e. all of the above BACK TO GAME

Page 16: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$300 Question

Stimulation of the sympathetic division of the autonomic nervous system during exercise results in secretion of epinephrine and norepinephrine into the blood; when exercise ends, the amount of epinephrine and norepinephrine in the blood decreases rapidly. This is an example of

a. acute hormone regulation

b. chronic hormone regulation

c. cyclic hormone regulation BACK TO GAME

ANSWER

Page 17: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$300 Answer

Stimulation of the sympathetic division of the autonomic nervous system during exercise results in secretion of epinephrine and norepinephrine into the blood; when exercise ends, the amount of epinephrine and norepinephrine in the blood decreases rapidly. This is an example of

a. acute hormone regulation

b. chronic hormone regulation

c. cyclic hormone regulationBACK TO GAME

Page 18: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$400 Question

When blood glucose levels increase, hormone "A" is secreted. Based on this information, hormone A is controlled by this:

a. changes in the level of a chemical in the blood

b. direct stimulation by the nervous system

c. stimulation by a hormone released from another endocrine gland

d. a hypothalamic releasing factor BACK TO GAME

ANSWER

Page 19: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$400 Answer

When blood glucose levels increase, hormone "A" is secreted. Based on this information, hormone A is controlled by this:

a. changes in the level of a chemical in the blood

b. direct stimulation by the nervous system

c. stimulation by a hormone released from another endocrine gland

d. a hypothalamic releasing factor BACK TO GAME

Page 20: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$500 Question

Hormone "A" stimulates the release of hormone "B." As levels of hormone "B" increase, the secretion of hormone "A" is inhibited. This control mechanism is this:

a. negative feedback

b. positive feedback

c. neural control

d. amplification

BACK TO GAME

ANSWER

Page 21: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Homeostasis:

$500 Answer

Hormone "A" stimulates the release of hormone "B." As levels of hormone "B" increase, the secretion of hormone "A" is inhibited. This control mechanism is this:

a. negative feedback

b. positive feedback

c. neural control

d. amplification

BACK TO GAME

Page 22: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$100 Question

Hormones bind to binding proteins in a reversible fashion.

True/False

BACK TO GAME

ANSWER

Page 23: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$100 Answer

Hormones bind to binding proteins in a reversible fashion.

True/False

BACK TO GAME

Page 24: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$200 Question

Water-soluble hormones, such as proteins, must do this:

a. pass through capillary cells

b. pass through pores in the capillary endothelium

c. be moved out of the capillary by active transport

d. remain in the blood

BACK TO GAME

ANSWER

Page 25: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$200 Answer

Water-soluble hormones, such as proteins, must do this:

a. pass through capillary cells

b. pass through pores in the capillary endothelium

c. be moved out of the capillary by active transport

d. remain in the blood

BACK TO GAME

Page 26: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$300 Question

These statements about these lipid-soluble hormones are true except:

a. have relatively long half-lives

b. are degraded rapidly by enzymes

c. have half-lives that increase and decrease slowly

d. regulate activities that have a long duration

BACK TO GAME

ANSWER

Page 27: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$300 Answer

These statements about these lipid-soluble hormones are true except:

a. have relatively long half-lives

b. are degraded rapidly by enzymes

c. have half-lives that increase and decrease slowly

d. regulate activities that have a long duration BACK TO GAME

Page 28: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$400 Question

This process makes hormones less active or increases elimination by attaching water-soluble molecules such as sulfate or glucuronic acid groups to them in the liver:

a. active transport

b. conjugation

c. excretion

d. metabolismBACK TO GAME

ANSWER

Page 29: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$400 Answer

This process makes hormones less active or increases elimination by attaching water-soluble molecules such as sulfate or glucuronic acid groups to them in the liver:

a. active transport

b. conjugation

c. excretion

d. metabolism

BACK TO GAME

Page 30: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$500 Question

A hormone is secreted in large amounts, modified by the liver, and excreted by the kidney rapidly, thus making its half-life very short. A patient that has liver and kidney disease would see this effect:

a. the hormone is not modified and excreted rapidly

b. increases blood levels of this hormone

c. concentration remains high for a longer time

d. decreases blood levels of this hormone

e. a, b and cBACK TO GAME

ANSWER

Page 31: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Transport and Metabolism:

$500 Answer

A hormone is secreted in large amounts, modified by the liver, and excreted by the kidney rapidly, thus making its half-life very short. A patient that has liver and kidney disease would see this effect:

a. the hormone is not modified and excreted rapidly

b. increases blood levels of this hormone

c. concentration remains high for a longer time

d. decreases blood levels of this hormone

e. a, b and c BACK TO GAME

Page 32: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors:

$100 Question

Thyroid hormones, testosterone, estrogen, aldosterone, and cortisol are small lipid-soluble hormones that bind to membrane-bound receptors.

True/False

BACK TO GAME

ANSWER

Page 33: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors:

$100 Answer

Thyroid hormones, testosterone, estrogen, aldosterone, and cortisol are small lipid-soluble hormones that bind to membrane-bound receptors.

True/False

BACK TO GAME

Page 34: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors:

$200 Question

Intracellular hormone receptors are found here:

a. floating freely in the cytoplasm of target cells

b. in the nucleus

c. in the mitochondria

d. in the endoplasmic reticulum

e. both a and bBACK TO GAME

ANSWER

Page 35: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors:

$200 Answer

Intracellular hormone receptors are found here:

a. floating freely in the cytoplasm of target cells

b. in the nucleus

c. in the mitochondria

d. in the endoplasmic reticulum

e. both a and b BACK TO GAME

Page 36: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors:

$300 Question

Given these events:1. cAMP is synthesized.2. The a subunit of G protein is activated.3. Phosphodiesterase breaks down cAMP.

Choose the arrangement that lists the events in the order they occur after a chemical signal binds to a receptor.

a. 1,2,3 c. 2,1,3

b. 1,3,2 d. 2,3,1 BACK TO GAME

ANSWER

Page 37: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors:

$300 Answer

Given these events:1. cAMP is synthesized.2. The a subunit of G protein is activated.3. Phosphodiesterase breaks down cAMP.

Choose the arrangement that lists the events in the order they occur after a chemical signal binds to a receptor.

a. 1,2,3 c. 2,1,3

b. 1,3,2 d. 2,3,1 BACK TO GAME

Page 38: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors:

$400 Question

These statements describe chemical signals binding to membrane-bound receptors except:

a. DNA produces mRNA

b. G proteins are activated

c. the receptor-hormone complex causes ion channels to open or close

d. the chemical signal is usually a large, water-soluble molecule

e. the cell's response is fast BACK TO GAME

ANSWER

Page 39: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors:

$400 Answer

These statements describe chemical signals binding to membrane-bound receptors except:

a. DNA produces mRNA

b. G proteins are activated

c. the receptor-hormone complex causes ion channels to open or close

d. the chemical signal is usually a large, water-soluble molecule

e. the cell's response is fast BACK TO GAME

Page 40: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors: $500 Question

Intracellular receptors are better adapted for mediating responses that last a relatively long time due to this:

a. cAMP activates existing enzymes in the cytoplasm

b. cAMP is broken down quickly

c. mRNA is synthesized

d. synthesis of new proteins

e. c and dBACK TO GAME

ANSWER

Page 41: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Receptors: $500 Answer

Intracellular receptors are better adapted for mediating responses that last a relatively long time due to this:

a. cAMP activates existing enzymes in the cytoplasm

b. cAMP is broken down quickly

c. mRNA is synthesized

d. synthesis of new proteins

e. c and d BACK TO GAME

Page 42: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$100 Question

If there is a decrease in the specific plasma protein to which a hormone binds, this occurs:

a. more free hormone occurs

b. less hormone binds to target cells

c. blood levels of the hormone increase

d. all of theseBACK TO GAME

ANSWER

Page 43: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$100 Answer

If there is a decrease in the specific plasma protein to which a hormone binds, this occurs:

a. more free hormone occurs

b. less hormone binds to target cells

c. blood levels of the hormone increase

d. all of these

BACK TO GAME

Page 44: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$200 Question

Down-regulation occurs because of this:

a. both hormone and receptor are taken into the cell by phagocytosis

b. receptor molecules are degraded more quickly

c. there is a decrease in the rate of receptor synthesis

d. all of theseBACK TO GAME

ANSWER

Page 45: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$200 Answer

Down-regulation occurs because of this:

a. both hormone and receptor are taken into the cell by phagocytosis

b. receptor molecules are degraded more quickly

c. there is a decrease in the rate of receptor synthesis

d. all of these

BACK TO GAME

Page 46: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$300 Question

This is NOT an intracellular mediator molecule:

a. cAMP

b. cGMP

c. ADH

d. DAG

e. IP3BACK TO GAME

ANSWER

Page 47: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$300 Answer

This is NOT an intracellular mediator molecule:

a. cAMP

b. cGMP

c. ADH

d. DAG

e. IP3BACK TO GAME

Page 48: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$400 Question

A hormone controls the concentration of some substance in the circulatory system. A tumor begins to produce that substance in large amounts in an uncontrolled fashion. The secretion rate for the hormone would:

a. increase by positive feedback

b. decrease by negative feedback

c. decrease by positive feedback

c. stay the same

BACK TO GAME

ANSWER

Page 49: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$400 Answer

A hormone controls the concentration of some substance in the circulatory system. A tumor begins to produce that substance in large amounts in an uncontrolled fashion. The secretion rate for the hormone would:

a. increase by positive feedback

b. decrease by negative feedback

c. decrease by positive feedback

c. stay the same BACK TO GAME

Page 50: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$500 Question

Given these events:1. activation of cAMP2. activation of genes3. enzyme activity altered

These events can occur when a hormone binds to an intracellular hormone receptor:

a. 1 c. 2,3

b. 1,2 d. 1,2,3

BACK TO GAME

ANSWER

Page 51: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

Grab Bag:

$500 Answer

Given these events:1. activation of cAMP2. activation of genes3. enzyme activity altered

These events can occur when a hormone binds to an intracellular hormone receptor:

a. 1 c. 2,3

b. 1,2 d. 1,2,3BACK TO GAME

Page 52: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

FINAL ROUND Question

This might be a consequence of trying to use a skin patch to administer a constant level of insulin to a patient who has diabetes mellitus:

a. too little insulin available after a meal when sugar levels are high

b. too much insulin available between meals when sugar levels are low

c. would control blood sugar levels well

d. a and b BACK TO GAME

ANSWER

Page 53: Functional Organization of the Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Introduction FINAL ROUND Homeostasis Transport

FINAL ROUND Answer

This might be a consequence of trying to use a skin patch to administer a constant level of insulin to a patient who has diabetes mellitus:

a. too little insulin available after a meal when sugar levels are high

b. too much insulin available between meals when sugar levels are low

c. would control blood sugar levels well

d. a and b BACK TO GAME