fully implantable transmitters. product range ecg, eeg, emg, sampled at 2khz. sna (sympathetic nerve...
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![Page 1: Fully implantable transmitters. product range ecg, eeg, emg, sampled at 2kHz. sna (sympathetic nerve activity) sampled at 8kHz temperature pressure (arterial](https://reader035.vdocuments.site/reader035/viewer/2022062803/56649c925503460f9494db14/html5/thumbnails/1.jpg)
fully implantable transmitters
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product range
ecg, eeg, emg, sampled at 2kHz.
sna (sympathetic nerve activity) sampled at 8kHz
temperature
pressure (arterial or venous blood, bladder, pleural), sampled at 500Hz
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transmitter features (1/2)
fully implantable
covered with medical grade silicone
completely sealed, with no battery to be replaced
transmission up to 5m
large and small animal models available
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transmitter features (2/2)
designed to be reused in multiple animals
pressure leads are filled with gel that prevents blood from entering the catheter lumen
ecg cables are filled with a biocompatible silicone to avoid contamination
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6 types of transmitters
1 pressure1 pressure + 1 biopotential1 biopotential2 biopotential1 SNA + 1 pressure1 SNA + 1 biopotential
temperature is standard in all devices
transmitters can remotely be turned on and off
no need to enter the room and disturb the animals
transmitters
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implants are fitted with a rechargeable battery
recharging is performed through patented inductive energy transfer
measurement from the subject may continue while the implant is recharged
there are no costs or down times due battery replacements and refurbishments
chargers
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rat data a few hours after implantation(courtesy Sanofi Aventis, France)
blood pressure, ecg, temperature
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implants for large animalscan run up to 200 hours without recharging
using the remote on/off feature, allow recording of 10mn every hour for more than 6 weeks
long transmission range (5m)
high signal resolution
ability pair or group house animals
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one receiver can acquire up to 12 transmitters
open system with analog outputs, compatible with all data acquisition systems
receivers
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recharging causes an increase in tissue temperature
false: continuous temperature recordings remain stable whether charging is off or on
misconceptions about inductive energy transfer
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misconceptions about inductive energy transfer
repeated recharging has long term consequences
false: experiments of more than 130 days, performed to verify pressure sensor stability, concurrently verified stability of all other physiological parameters
recharging influences physiological parameters
false: recordings show that blood pressure, heart rate, ecg morphology, and eeg power spectrum remain stable independent of charging status
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sympathetic nerve activity (SNA) by telemetry
a challenging application
small signal amplitude (+/- 60µV)
high frequency
high sampling rate required
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sympathetic nerve activity (SNA) by telemetry
TR system provides
8kHz sampling rate
integrated output with: adjustable gain adjustable integrator time constant
audio output
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sympathetic nerve activity (SNA) by telemetry
electrodes and placement of electrodes
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sympathetic nerve activity (SNA) by telemetry
sample SNA recording
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feature comparisonTelemetry Research competitor
sampling frequency up to 8000 Hz <= 500Hz
pressure measurement
gel filled catheter yes yes
battery rechargeable return to factory
range of transmitter up to 5 m up to 1 m
group housing up to 12 1
software open platform specific software
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visit our websites for complete product descriptions, case studies, a knowledge base, & frequently asked questions:
www.emka.fr
website
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contact us!
please contact us to see how we can help you meet your implantable telemetry research goals!
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