fp7 calls published - era-edta · collaborative project (large scale integrating project). ec...

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FP7 Calls published

The European Commission has recently published a round of FP7 calls under the Cooperation and Capacities themes.

As expected, there are no renal-specific calls in this round. The calls that were flagged up to EKHA members earlier in the year from the draft text due to their potential links with kidney disease appear in the final call:

FP7 – HEALTH – 2010 – single stage

1.4 Innovative therapeutic approaches and interventions

1.4.1 Translational research on cell-based immunotherapy (Collaborative project – large-scale integrating project. 6-12 million Euros EC contribution)

2.4 Translational research in other major diseases 2.4.2 Cardiovascular diseases

2.4.2.2 New approaches to reduce ischemic damage to the heart (Collaborative project – small or medium scale focused research project. Max 6 million Euros EC contribution)

2.4.2.4 Diastolic heart failure (Collaborative project – large scale integrating project. 6 -12 million Euros EC contribution)

2.4.5 Other chronic diseases

2.4.5.2 Infection and dysbiosis as the triggers of the development of the inflammatory processes in allergies and autoimmune diseases (Collaborative project – small or medium scale focused research project. Max 6 million Euros EC contribution)

The full text of this call is attached to the email (FP7-Health 2010-Single Stage) To access the application form and guide for applicants for this call, please go to http://cordis.europa.eu/fp7/dc/index.cfm?fuseaction=UserSite.CooperationDetailsCallPage&call_id=278#infopack The deadline for single stage proposals is 19 November 2009 17:00 Brussels local time

Two-stage submissions involve a preliminary evaluation of stage 1 proposals which set out the main aims of the project, followed by a final evaluation of the full stage 2 proposals.

FP7 – HEALTH – 2010 – two-stage

Again, there are no renal-specific calls, but the following may be of interest: 1. Biotechnology, diagnosis and monitoring 1.2 Detection, diagnosis and monitoring

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HEALTH-2010-1.2-1: Tools for the identification and the detection of biomarkers in clinical samples and patients (Collaborative project – small or medium-scale focused research project. Max 6 million Euros EC contribution)

2. Translating research for human health 2.1 Integrating biological data and processes: large-scale data gathering, systems biology

2.1.2 Systems Biology HEALTH 2.1.2-1: Tackling Human Diseases through Systems Biology Approaches (Collaborative project – large scale integrating project. 6 – 12 million Euros EC contribution) HEALTH 2.1.2-2: Establishing the foundations to enable systems biology of complex biological processes relevant to human health (Network of Excellence. Max 12 million Euros EC contribution)

3. Optimising the delivery of healthcare to European citizens

3.1 Translating the results of clinical research outcome into clinical practice including better use of medicines, and appropriate use of behavioural and organizational interventions and new health therapies and technologies.

HEALTH 2010-3.1-1 Better understanding of dissemination and implementation strategies (Collaborative project – small or medium scale focused research project. Max 3 million Euros EC contribution)

The full text of this call is attached to the email (FP7-Health 2010-Two Stage) To access the application form and guide for applicants for this call, please go to http://cordis.europa.eu/fp7/dc/index.cfm?fuseaction=UserSite.CooperationDetailsCallPage&call_id=279 The deadline for the first stage of two- stage proposals is 29 November 2009 17:00 Brussels local time and the second stage is 11 February 2009 17:00 Brussels local time

The aim of the research infrastructures theme is to optimize the use and development of the best research infrastructures existing in Europe and to create new pan-European research infrastructures in the field of science and technology. The following calls may be of interest to the renal community:

FP7 – Capacities – RESEARCH INFRASTRUCTURES

1.1 Support to existing research infrastructures 1.1.1 Integrating Activities (162 million EUR EC Contribution)

Life Sciences INFRA-2010-1.1.12 Large-scale bio-banks for clinical and epidemiological studies INFRA-2010-1.1.13 Facilities for high throughput DNA sequencing and human genotyping INFRA-2010-1.1.14 High throughput facilities for proteome analysis INFRA-2010-1.1.15 Good Manufacturing Practices (GMP) facilities for advanced gene and cell therapy research



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1.2 Support to new research infrastructures 1.2.2 Construction of new infrastructures (or major upgrades) – preparatory phase (45 million EUR EC contribution) INFRA-2010-2.2.6 EU-OPENSCREEN (European Infrastructure of Open Screening Platforms for chemical biology)

INFRA-2010-2.2.7 EuroBioImaging (Research infrastructure for imaging technologies in biological and biomedical sciences) INFRA-2010-2.2.8 High Security BLS4 Laboratory (Upgrade of the High Security Laboratories for the study of level 4 pathogens)

The full text of this call is attached to the email (FP7-Health 2010-Research Infrastructures) To access the application form and guide for applicants for this call, please go to http://cordis.europa.eu/fp7/dc/index.cfm?fuseaction=UserSite.CapacitiesDetailsCallPage&call_id=262



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Call title: HEALTH-2010-single-stage Call identifier: FP7-HEALTH-2010-single-stage

Proposal submission and evaluation: Single-stage procedure

Date of publication: 30 July 2009.

Deadline: 19 November 2009 at 17:00:00 (Brussels local time).1

Indicative budget: EUR 333.5 million from the 2010 budget2

The budget for this call is indicative. The final budget awarded to actions implemented through calls for proposals may vary:

• The final budget of the call may vary by up to 10% of the total value of the indicated budget for each call; and

• Any repartition of the call budget may also vary by up to 10% of the total value of the indicated budget for the call.

Table 1

ACTIVITY/AREA Indicative budget(EUR million)

1. BIOTECHNOLOGY, GENERIC TOOLS AND MEDICAL TECHNOLOGIES FOR HUMAN HEALTH

1.1. HIGH-THROUGHPUT RESEARCH 1.2 DETECTION, DIAGNOSIS AND MONITORING 1.3 SUITABILITY, SAFETY, EFFICACY OF THERAPIES 1.4 INNOVATIVE THERAPEUTIC APPROACHES AND INTERVENTIONS

49

2. TRANSLATING RESEARCH FOR HUMAN HEALTH

2.1. LARGE-SCALE DATE GATHERING AND SYSTEMS BIOLOGY 16

2.2 RESEARCH ON THE BRAIN AND RELATED DISEASES, HUMAN DEVELOPMENT AND AGEING 0.5

2.3. TRANSLATIONAL RESEARCH IN MAJOR INFECTIOUS DISEASES: TO CONFRONT MAJOR THREATS TO PUBLIC HEALTH 78

2.4. TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES 112

3. OPTIMISING THE DELIVERY OF HEALTHCARE TO EUROPEAN CITIZENS

3.2 QUALITY, EFFICIENCY AND SOLIDARITY OF HEALTH CARE SYSTEMS 14

3.4 INTERNATIONAL PUBLIC HEALTH AND HEALTH SYSTEMS 14

4. OTHER ACTIONS ACROSS THE HEALTH THEME

4.1. COORDINATION AND SUPPORT ACTIONS ACROSS THE THEME 2

4.2. RESPONDING TO EU POLICY NEEDS

4.2a 40

4.2b 8

1 The Director-General responsible for this call may delay this deadline by up to two months. 2 Under the condition that the preliminary draft budget for 2010 is adopted without modifications by the budgetary authority.

2

Table 2: Topics called: Activity/Area Topics called Funding Schemes and

particular requirements

1.BIOTECHNOLOGY, GENERIC TOOLS AND MEDICAL TECHNOLOGIES FOR HUMAN HEALTH

1.1 HIGH-THROUGHPUT RESEARCH 1.1 HEALTH.2010.1.1-1: Harmonisation of phenotyping and

biosampling for human large-scale research biobanks. Collaborative project (Large-scale integrating project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. Only up to one proposal can be selected.

1.1 HEALTH.2010.1.1-3: High-throughput analysis of post-translational modifications of proteins.

SICA, Collaborative Project (Small or medium-scale focused research project). Target Region: China. EC contribution per project: max. EUR 3 000 000. Only up to one proposal can be selected.

1.2 DETECTION, DIAGNOSIS AND MONITORING 1.2 HEALTH.2010.1.2-2: Stratification approaches and

methodologies to select from a wide range of biomarkers relevant candidates for clinical validation.

Coordination and Support Action (Supporting Action). EC contribution per project: max. EUR 500 000. Only up to one proposal can be selected.

1.2 HEALTH.2010.1.2-3: Harmonization, validation and standardisation in genetic testing.

Coordination and Support Action (Coordinating Action). EC contribution per project: max. EUR 2 000 000. Only up to one proposal can be selected.

1.2 HEALTH.2010.1.2-4: Early events in acute hepatitis C virus (HCV) infection with the aim to identify new biomarkers.

SICA for Mediterranean Partner Countries Collaborative Project (Small or medium-scale focused research project). EC contribution per project: max. EUR 3 000 000. One or more proposals can be selected.

1.4 INNOVATIVE THERAPEUTIC APPROACHES AND INTERVENTIONS

1.4 HEALTH.2010.1.4-1: Translational research on cell-based immunotherapy.

Collaborative Project (Large scale integrating project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. One or more proposals can be selected.

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2.1. INTEGRATING BIOLOGICAL DATA AND PROCESSES: LARGE-SCALE DATA GATHERING, SYSTEMS BIOLOGY

2.1.1. Large-Scale Data Gathering

2.1.1. HEALTH.2010.2.1.1-1: Large-scale efforts in mouse functional genomics to determine the functions of genes and their involvement in disease.

Collaborative Project (Large-Scale integrating project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000 Only up to one proposal can be selected.

2.1.1. HEALTH.2010.2.1.1-2: Coordination action(s) on standards in large scale data gathering.

Coordination and Support Action (Coordinating Action). EC contribution per project: max. EUR 2 000 000. One or more proposals can be selected.

2.1.2. Systems Biology

2.1.2. HEALTH.2010.2.1.2-3: Developing new and improving existing mathematical algorithms for systems biology.

SICA Collaborative Project (Small or medium-scaled focused research projects) with focus on EECA. EC contribution per project: max. EUR 3 000 000. Only up to one proposal can be selected.

2.2. RESEARCH ON THE BRAIN AND RELATED DISEASES, HUMAN DEVELOPMENT AND AGEING

2.2.2. Human development and ageing

2.2.2. HEALTH.2010.2.2.2-5: Frailty and its implications in modern society.

Coordination and Support Action (Supporting Action). EC contribution per project: max. EUR 500 000. Only up to one proposal can be selected.

2.3. TRANSLATIONAL RESEARCH IN MAJOR INFECTIOUS DISEASES: TO CONFRONT MAJOR THREATS TO PUBLIC HEALTH

2.3.2. HIV/AIDS, malaria and tuberculosis

2.3.2. HEALTH.2010.2.3.2-1: Target characterisation and hit-to-lead progression in tuberculosis (TB) drug development.

Collaborative project (Large-scale integrating project). EC contribution per project: min. EUR 6 000 000 – max.EUR 12 000 000. Only up to one proposal can be selected.

2.3.2. HEALTH.2010.2.3.2-2: Lead optimisation and late preclinical development in tuberculosis (TB) drugs.

Collaborative project (Small or medium-scale focused research project). EC contribution per project: max EUR 6 000 000. One or more proposals can be selected.

4

2.3.2. HEALTH.2010.2.3.2-3. European network of cohort studies

on HIV/AIDS. Network of Excellence. EC contribution per project: max. EUR 12 000 000. Only up to one proposal can be selected.

2.3.3. Potentially new and re-emerging epidemics

2.3.3. HEALTH.2010.2.3.3-1: Biology and control of vector-borne infections in Europe.

Collaborative project (Large scale integrating project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. Only up to one proposal can be selected.

2.3.3. HEALTH.2010.2.3.3-2: Drug lead discovery against RNA viruses.

Collaborative project (Large scale Integrating Project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. Only up to one proposal can be selected.

2.3.3. HEALTH.2010.2.3.3-3: Integrated disease-specific research on West Nile Virus infections, Chikungunya and/or Crimean Congo Haemorrhagic Fever.

Collaborative projects (Small or medium-scale focused research project). EC contribution per project: max. EUR 3 000 000. One or more proposals can be selected.

2.3.4 Neglected infectious diseases

2.3.4. HEALTH.2010.2.3.4-1: Vaccines for childhood bacterial diarrhoeal diseases.

SICA Collaborative Project (Large scale integrating project) Target Region: all ICPC. EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. Only up to one proposal can be selected.

2.3.4. HEALTH.2010.2.3.4-2: Comprehensive control of Neglected Infectious Diseases.

SICA Collaborative Project (Small- or medium scale focused research project) Target Region: all ICPC. EC contribution per project: max. EUR 6 000 000. One or more proposals can be selected.

2.3.4. HEALTH.2010.2.3.4-3: Next generation of researchers for Neglected Infectious Diseases.

Coordination and Support Action (Coordinating action). EC contribution per project: max. EUR 2 000 000. One or more proposals can be selected.

2.4. TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES

2.4.1. Cancer

2.4.1. HEALTH.2010.2.4.1-2: Structuring translational cancer research between cancer research centres in Europe.

Network of Excellence. EC contribution per project: max. EUR 12 000 000. Only up to

5

one proposal can be selected.

2.4.1. HEALTH.2010.2.4.1-3: Structuring clinical research in paediatric and adolescent oncology in Europe.

Network of Excellence. EC contribution per project: max. EUR 12 000 000. Only up to one proposal can be selected.

2.4.2. Cardiovascular diseases

2.4.2. HEALTH.2010.2.4.2-1: Reducing in-stent thrombosis. Collaborative Project (Small or medium-scale focused research project). EC contribution per project: max. EUR 6 000 000. Only up to one proposal can be selected.

2.4.2. HEALTH.2010.2.4.2-2: New approaches to reduce ischemic damage to the heart.

Collaborative Project (Small or medium-scale focused research project). EC contribution per project: max. EUR 6 000 000. Only up to one proposal can be selected.

2.4.2. HEALTH.2010.2.4.2-3: Identifying new therapeutic targets in atrial fibrillation.

Collaborative Project (Large scale integrating project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. Only up to one proposal can be selected.

2.4.2. HEALTH.2010.2.4.2-4: Diastolic heart failure. Collaborative Project (Large scale integrating project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. Only up to one proposal can be selected.

2.4.4. Rare diseases

2.4.4. HEALTH.2010.2.4.4-1: Clinical development of substances with a clear potential as orphan drugs.

Collaborative Project (Small or medium-scale focused research project). EC contribution per project: max. EUR 6 000 000. One or more proposals can be selected.

2.4.5. Other chronic diseases

2.4.5. HEALTH.2010.2.4.5-1: Investigation of the mechanisms of initiation of allergic response, genetic predisposition, biomarkers and identification of targets for therapy.

Collaborative Project (Large-scale integrating research project. EC contribution per project: min EUR 6 000 000 - max. EUR 12 000 000. Only up to one proposal can be selected.

2.4.5. HEALTH.2010.2.4.5-2: Infection and dysbiosis as the triggers of the development of inflammatory processes in allergies and autoimmune diseases.


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3.2. QUALITY, EFFICIENCY AND SOLIDARITY OF HEALTHCARE SYSTEMS INCLUDING TRANSITIONAL HEALTH SYSTEMS

3.2. HEALTH.2010.3.2-1: Financing systems' effect on quality of healthcare.


3.2. HEALTH.2010.3.2-2: Risk adjustment algorithms for better health insurance coverage.


3.4. INTERNATIONAL PUBLIC HEALTH & HEALTH SYSTEMS 3.4 HEALTH.2010.3.4-5: Assessment of migrants' health,

disease patterns and impact on health systems Coordination and Support Action (Coordinating Action) (Target Regions: countries from Latin America and Mediterranean partner countries (MPC). At least 6 independent legal entities, of which, 3 must be established in different MS or AC and the other 3 must be established in different international cooperation partner countries (ICPC) from the above mentioned target regions (LA, MPC).Max. EC contribution/proposal: EUR 2 000 000.Only up to one proposal can be selected per region for this topic

3.4. HEALTH.2010.3.4-6: Impact and cost-effectiveness of existing major health programmes.

SICA Collaborative Project (Small or medium-scale focused research project) Target Regions: all ICPC. EC contribution per project: max. EUR 3 000 000. One or more proposals can be selected.

3.4. HEALTH.2010.3.4-7: Financing models for accessible health care.

SICA Collaborative Project (Small or medium-scale focused research project) Target Regions: all ICPC. EC contribution per project: max. EUR 3 000 000. One or more proposals can be selected.

4. OTHER ACTIONS ACROSS THE HEALTH THEME

4.1. COORDINATION AND SUPPORT ACTIONS ACROSS THE THEME

4.1. HEALTH.2010.4.1-1: Promoting participation of high-technology research-intensive SMEs, operating in the

Coordination Action or Support Action (Coordinating

7

Health sector. Action). EC contribution per project: max. EUR 2 000 000. Only up to one proposal can be selected.

4.2. RESPONDING TO EU POLICY NEEDS

4.2a

4.2. HEALTH.2010.4.2-1: Off-patent medicines for children. Collaborative Project (Small or medium-scale focused research project). EC contribution per project: max. EUR 6 000 000. One or more proposals can be selected.

4.2. HEALTH.2010.4.2-2: International paediatric initiative. Network of Excellence. EC contribution per project: max. EUR 12 000 000. Only up to one proposal can be selected.

4.2. HEALTH.2010.4.2-3: Adverse drug reaction research. Collaborative Project (Small or medium-scale focused research projects). EC contribution per project: max. EUR 3 000 000. One or more proposals can be selected.

4.2b

4.2. HEALTH.2010.4.2-4: International pluripotent stem cell registry.


4.2. HEALTH.2010.4.2-5: Methodology to evaluate and monitor health policy implementation and performance of EU funded interventions in developing countries.

SICA Collaborative Project (Small or medium-scale focused research project) Target Regions: all ICPC. EC contribution per project: max. EUR 3 000 000. Only up to one proposal can be selected.

4.2. HEALTH.2010.4.2-6: Impact of EU legislation on health research.

Coordination Action or Support Action (Supporting Action). EC contribution per project: max. EUR 500 000. One or more proposals can be selected.

4.2. HEALTH.2010.4.2-7: International forum for European life sciences funders and performers.


4.2. HEALTH-2010.4.2-8: Coordination action in support of the implementation by participating States of a Joint Programming Initiative for combating neurodegenerative diseases, in particular Alzheimer's disease.

Coordination and Support Action (Coordinating Action). EC contribution per project: max. EUR 2 000 000. Only up

8

to one proposal can be selected.

Eligibility criteria for each proposal are checked by Commission staff before the evaluation begins. Proposals which do not fulfil these criteria will not be included in the evaluation.

Eligibility conditions:

• The general eligibility criteria are set out in Annex 2 of the work programme, and in the guide for applicants for each funding scheme.

In addition, specific eligibility criteria apply to this call as set out below: • Only information provided in part A of the proposal will be used to determine whether the

proposal is eligible with respect to budget thresholds and/or minimum number of eligible participants.

• Please note that the completeness criterion also includes that part B of the proposal shall be readable, accessible and printable

• It is important to note that the upper and lower limits for the EU contribution given per topic in table 2 of this call fiche, will be applied as an additional eligibility criterion and that proposals which do not respect these limits will be considered as ineligible.

• The minimum number and type of participating legal entities for all funding schemes is set out in the FP7 Rules for Participation and summarised in the following table for the funding schemes used in this call. There may be exceptions to the minimum number and participant type, which are specified in the topic description in the work programme.

Table 3: Eligibility conditions for participation

Funding scheme Minimum conditions Collaborative Project

At least 3 independent legal entities, each of which is established in a MS or AC, and no 2 of which are established in the same MS or AC

Networks of Excellence At least 3 independent legal entities, each of which is established in a MS or AC, and no 2 of which are established in the same MS or AC

Collaborative project for specific cooperation Action (SICA) dedicated to international cooperation partner countries

At least 4 independent legal entities. Of these, 2 must be established in different MS or AC. The other 2 must be established in different international cooperation partner countries (ICPC).

Coordination and Support Action (coordinating action)

At least 3 independent legal entities, each of which is established in a MS or AC, and no 2 of which are established in the same MS or AC

Coordination and Support Action (supporting action)

At least 1 independent legal entity.

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Evaluation procedure: The basic principles of the Evaluation criteria for proposals are described in Annex 2 of the work programme. However, for this call, the priority order for proposals with the same score will be determined in the manner described under 'Proposal ranking" (see below). For all proposals submitted to this call the evaluation shall follow a single stage procedure. The proposers are requested to follow the instructions set out in the guide for applicants for the appropriate funding scheme and in the proposal part B template available through the EPSS, including page number limitations and a minimum font size of 11. The Commission will instruct the independent external experts to disregard any pages in excess of these limits. The proposals will be evaluated by independent external experts on the basis of three evaluation criteria. The individual evaluation will be carried out remotely and the consensus meetings of evaluators will be held in Brussels.

Evaluation criteria and thresholds: For this call the following criteria and thresholds are applied. For each criterion marks from 0 to 5 will be given, with the possibility of half point scores. For proposals failing to achieve a threshold for a criterion, the evaluation of the proposal will be stopped at the first criterion failing a threshold. Therefore for such proposals the ESR (evaluation summary report) will not contain marks and comments for the remaining criteria. Successful proposals must pass the following minimum thresholds:

Table 4: Thresholds for evaluation criteria

Criterion Minimum threshold

S/T quality 3/5

Implementation 3/5

Impact 3/5

Overall threshold 10/15

In line with the objectives of each topic, additional evaluation criteria may be indicated in the work programme. Proposal ranking: The series of priority lists will be prepared by the panels of external experts, per indicative sub-budget line as set out in this call fiche. The aspects taken into account for establishing a priority order for ranking of proposals are set out in annex 2 of the work programme. There will be differing numbers of proposals short-listed according to the funding scheme and topic:

For Large-scale Integrating Projects, Networks of Excellence, Coordination and Support Actions, only up to one proposal can be funded per topic, unless otherwise stated in the topic description in the topic description in table 2 (particular requirements for specific topics).

For small and medium-scale Focused Research Projects, one or more proposals can be funded per topic, unless otherwise stated in table2.

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However, there may be topics for which no proposals are of sufficient quality to be selected for funding, as there will be competition within topics and between topics on the basis of the quality of the proposals.

The Commission ranked lists of proposals to be retained for negotiation will be based on the priority list established by the panel of independent external experts taking into account the budget available for each budget line (as indicated in this call for proposals). For each budget line, a number of proposals below the indicative budget cut-off line on the Commission ranked list may be kept on a reserve list to allow for eventualities such as the failure of negotiations on grant agreements, the withdrawal of proposals, budget savings agreed during negotiation, or the availability of additional budget from other sources.

Indicative evaluation and contractual timetable: The evaluation should be finalised in February/March 2010. Overall evaluation results are estimated to be available within 4 months after the closure date for the call. It is expected that grant agreement negotiations for short-listed proposals would begin in May/June 2010.

Consortium agreements: Participants in large-scale integrating collaborative projects or networks of excellence are required to conclude a consortium agreement. For small- and medium scale collaborative projects a consortium agreement is not mandatory but recommended. For coordination and support actions a consortium agreement is not required. The forms of grants and maximum reimbursement rates which will be offered are specified in Annex 3 to the Cooperation work programme.

Flat rates to cover subsistence costs: In accordance with Annex 3 of this work programme, this call provides for the possibility to use flat rates to cover subsistence costs incurred by beneficiaries during travel carried out within grants for indirect actions. For further information, see the relevant guides for applicants for this call. The applicable flat rates are available at the following website: http://cordis.europa.eu/fp7/find-doc_en.html under 'Guidance documents/Flat rates for daily allowances'.

1

Call title: HEALTH-2010-two-stage

Call identifier: FP7-HEALTH-2010-two-stage

Proposal submission and evaluation: two-stage procedure.

Date of publication: 30 July 2009

Deadline for stage 1 proposals: 29 October 2009 at 17:00:00 (Brussels local time)1

Indicative budget: EUR 205 million from the 2010 budget2

The budget for this call is indicative. The final budget awarded to actions implemented through calls for proposals may vary:

• The final budget of the call may vary by up to 10% of the total value of the indicated budget for each call; and

• Any repartition of the call budget may also vary by up to 10% of the total value of the indicated budget for the call.

Table 1

ACTIVITY/AREA Indicative budget(EUR million)

1. BIOTECHNOLOGY, GENERIC TOOLS AND MEDICAL TECHNOLOGIES FOR HUMAN HEALTH

1.2 DETECTION, DIAGNOSIS AND MONITORING 25


2.1. LARGE-SCALE DATE GATHERING AND SYSTEMS BIOLOGY 64

2.2 RESEARCH ON THE BRAIN AND RELATED DISEASES, HUMAN DEVELOPMENT AND AGEING 32

2.4. TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES 66

3. OPTIMISING THE DELIVERY OF HEALTHCARE TO EUROPEAN CITIZENS 18

1 The Director-General responsible for this call may delay this deadline by up to two months. 2 Under the condition that the preliminary draft budget for 2010 is adopted without modifications by the budgetary authority.

2

Table 2: Topics called:

Activity/Area Topics called Funding Schemes and particular requirements

1.BIOTECHNOLOGY, GENERIC TOOLS AND MEDICAL TECHNOLOGIES FOR HUMAN HEALTH

1.2 DETECTION, DIAGNOSIS AND MONITORING 1.2 HEALTH.2010.1.2-1: Tools for the identification and the

detection of biomarkers in clinical samples and patients. Collaborative Project (Small or medium-scale focused research project). EC contribution per project: max. EUR 6 000 000. One or more proposals can be selected.


2.1. INTEGRATING BIOLOGICAL DATA AND PROCESSES: LARGE-SCALE DATA GATHERING, SYSTEMS BIOLOGY

2.1.2. Systems Biology

2.1.2. HEALTH.2010.2.1.2-1: Tackling Human Diseases through Systems Biology Approaches.

Collaborative Project (Large-Scale integrating project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. One or more proposals can be selected.

2.1.2. HEALTH.2010.2.1.2-2: Establishing the foundations to enable systems biology of complex biological processes relevant to human health.

Network of Excellence. EC contribution per project: max. EUR 12 000 000. One or more projects can be selected.

2.2. RESEARCH ON THE BRAIN AND RELATED DISEASES, HUMAN DEVELOPMENT AND AGEING

2.2.2. Human development and ageing

2.2.2. HEALTH.2010.2.2.2-1: Role of early-life developmental processes in longevity determination.

Collaborative project (Large-scale integrating project). EC contribution per project: min. EUR 6 000 000 – max. EUR 12 000 000. Only up to one proposal can be selected.

2.2.2. HEALTH.2010.2.2.2-2: Homeostasis in human development and its effects on lifespan.

Collaborative project (Small or medium-scale focused research project). EC contribution per project: max. EUR 6 000 000. Only up to one proposal can be selected.

2.2.2. HEALTH.2010.2.2.2-3: Integrative systems biology and comparative genomics for studying human ageing.

Collaborative Project (Large-Scale integrating project). EC contribution per project: min. EUR 6 000 000 - max. EUR 12 000 000. Only up to one proposal can be selected.

2.2.2. HEALTH.2010.2.2.2-4: Markers of cellular senescence for human ageing

Collaborative Projects (Small or medium-scale focused research project). EC contribution per project: max.

3

EUR 3 000 000. Only up to one proposal can be selected.

2.4. TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES

2.4.1. Cancer

2.4.1. HEALTH.2010.2.4.1-5: Structuring clinical research on rare cancers in adults.

Collaborative Project (Small or medium-scale focused research project). EC contribution per project: max EUR 6 000 000. One or more proposals can be selected.

2.4.1. HEALTH.2010.2.4.1-6: Translational research on cancers with poor prognosis.


2.4.1. HEALTH.2010.2.4.1-7: Predicting long-term side effects to cancer therapy.


2.4.1. HEALTH.2010.2.4.1-8: Predicting individual response and resistance to cancer therapy.


2.4.1. HEALTH.2010.2.4.1-9. Optimising the delivery of (chemo)radiotherapy and/or surgery to cancer patients.



3.1. TRANSLATING THE RESULTS OF CLINICAL RESEARCH OUTCOME INTO CLINICAL PRACTICE INCLUDING BETTER USE OF MEDICINES, AND APPROPRIATE USE OF BEHAVIOURAL AND ORGANISATIONAL INTERVENTIONS AND NEW HEALTH THERAPIES AND TECHNOLOGIES

3.1. HEALTH.2010.3.1-1: Better understanding of dissemination and implementation strategies.

Collaborative Project (small or medium-scale focused research project). EC contribution per project: max. EUR 3 000 000. One or more proposals can be selected.

Eligibility criteria for each proposal are checked by Commission staff before the evaluation begins. Proposals which do not fulfil these criteria will not be included in the evaluation.

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Eligibility conditions (stage 1 and stage 2):

The general eligibility criteria are set out in Annex 2 of this work programme, and in the guide for applicants for each funding scheme.

In addition, specific eligibility criteria apply to this call as set out below: • Please note that the completeness criterion also includes that part B of the proposal

shall be readable, accessible and printable.

• Proposals must be received by the Commission via the electronic proposal submission system respecting the deadline (date and time) as set out above.

• It is important to note that the upper and lower limits for the EU contribution given per topic in table 2 of this call fiche, will be applied as an additional eligibility criterion and that proposals (stage 1 and stage 2) which do not respect these limits will be considered as ineligible.

• The minimum number and type of participating legal entities for all funding schemes is set out in the FP7 Rules for Participation and summarised in the following table for the funding schemes used in this call at stage 2, unless otherwise specified in the topic description.

• At stage 2, only information provided in part A of the proposal will be used to determine whether the proposal is eligible with respect to budget thresholds and/or minimum number of eligible participants.

Table 3: Eligibility conditions for participation

Funding scheme Minimum participation conditions Collaborative project At least 3 independent legal entities, each of

which is established in a MS or AC, and no two of which are established in the same MS or AC.

Networks of Excellence At least 3 independent legal entities, each of which is established in a MS or AC, and no 2 of which are established in the same MS or AC

Evaluation procedure: The basic principles of the Evaluation criteria for proposals are described in annex 2 of the work programme. However, for this call, the priority order for proposals with the same total score will be determined in the manner described under 'Proposal ranking" (see below). For all proposals submitted to this call the evaluation shall follow a two-stage procedure. The proposals will be evaluated by independent external experts. Stage 1 proposals Stage 1 proposals must be submitted by the deadline mentioned above. Stage 1 proposals should follow the instructions set out in the guide for applicants and in the proposal part B template available through EPSS. Proposals should focus on the overall scientific and technological content and on clear identification of the milestones to be reached

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(intended results), their intended use and the expected impact (scientific, economic, social, environmental, etc.) in a maximum of 5 pages (excluding the cover page and the required tables). Applicants should also provide an additional 1 page (maximum) to describe the consortium and the estimated financial resources involved. The maximum page limits of each section must be respected. The Commission will instruct the independent external experts to disregard any pages in excess of these limits. A minimum font size of 11 is required. Stage 1 proposals will be individually evaluated remotely by independent external experts and discussed in consensus meetings. Stage 1 proposals will be evaluated on the basis of the following two criteria: Scientific/technological quality and Impact. For each criterion, marks from 0 to 5 will be given, with the possibility of half-point scores. Proposals must pass the minimum thresholds as follows:

Table 4: Thresholds for evaluation criteria for first stage


S/T quality 4/5

Impact 3/5


Coordinators of proposals retained at stage 1 (proposals passing the evaluation thresholds) will be invited to submit a complete proposal (stage 2 proposal) that will then be evaluated against the entire set of evaluation criteria. In line with the objectives of each topic, additional eligibility criteria may be indicated in the work programme. Proposals will be retained at stage 1 (proposals passing the evaluation thresholds) to a total budgetary value of maximum 3 times the indicative budget for this call.

Stage 2 proposals The proposers are requested to follow the page limitation instructions as set out in the guide for applicants and in the proposal part B template available through the EPSS, respecting page number limitations and a minimum font size of 11. The Commission will instruct the experts to disregard any pages in excess of these limits.

The deadline for submission for stage 2 proposals will be specified in the invitation to submit. The indicative deadline for stage 2 proposals is: March 2010.

Stage 2 proposals will be individually evaluated remotely by external experts and discussed in consensus meetings.

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Stage 2 proposals are evaluated on the basis of the following three criteria: Scientific/technological quality and Implementation and Impact. For each criterion, marks from 0 to 5 will be given, with the possibility of half-point scores. Proposals must pass the minimum thresholds as follows:

Table 5: Thresholds for evaluation criteria for second stage


S/T quality 4/5

Implementation 3/5

Impact 3/5


Proposal ranking at stage 2: Priority lists will be prepared per indicative budget (see

table 1 of this call fiche) by the panels of external experts. The aspects taken into account for establishing a priority order for ranking of proposals are set out in Annex 2 of this work programme.

There will be differing numbers of proposals short-listed according to the funding scheme and topic:

For Large-scale Integrating Projects, Networks of Excellence, Coordination and Support Actions, only up to one proposal can be funded per topic, unless otherwise stated in the topic description in the topic description in table 2 (particular requirements for specific topics).

For small and medium-scale Focused Research Projects, one or more proposals can be funded per topic, unless otherwise stated in table2.

However, there may be topics for which no proposals are of sufficient quality to be selected for funding, as there will be competition within topics and between topics on the basis of the quality of the proposals. The Commission ranked lists of proposals to be retained for negotiation will be based on the priority lists established by the panels of external experts taking into account the budget available (as indicated in this call for proposals). A number of proposals below the indicative budget cut-off line on the Commission ranked lists may be kept on a Commission reserve lists to allow for eventualities such as the failure of negotiations on grant agreements, the withdrawal of proposals, budget savings agreed during negotiation, or the availability of additional budget from other sources. Indicative evaluation and contractual timetable: The first stage evaluation should be finalised at the end of January 2010. The evaluation of the second stage is expected to take place in May 2010. Overall evaluation results: estimated to be available within 3 months after the closure date for stage 2 proposals. It is expected that grant agreement negotiations for short-listed proposals would begin in July 2010.

Consortium agreements: Participants in all types of collaborative projects or networks of excellence are required to conclude a consortium agreement.

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Forms of grant and maximum reimbursement rates for projects funded through the Cooperation work programme are given in Annex 3. Flat rates to cover subsistence costs: In accordance with Annex 3 of this work programme, this call provides for the possibility to use flat rates to cover subsistence costs incurred by beneficiaries during travel carried out within grants for indirect actions. For further information, see the relevant guides for applicants for this call. The applicable flat rates are available at the following website: http://cordis.europa.eu/fp7/find-doc_en.html under 'Guidance documents/Flat rates for daily allowances'.

Call title: Call 6: FP7-INFRASTRUCTURES-2010-1

• Call identifier: FP7-INFRASTRUCTURES-2010-1

• Date of publication: 30 July 2009

• Deadline1: 3 December 2009, at 17.00.00, Brussels local time.

• Indicative budget2: EUR 216.94 million3

Line of action/Activity EUR million indicative

1.1 Support to existing research infrastructures

1.1.1 Integrating Activities 162.00

1.2 Support to new research infrastructures

1.2.2 Construction of new infrastructures (or major upgrades) - preparatory phase 45.00

1.3 Support to policy development and programme implementation 9.94

• Topics called

Line of action/Activity Topics called Funding

scheme(s)

1.1 Support to existing research infrastructures

1.1.1 Integrating Activities

Social Sciences and Humanities

° INFRA-2010-1.1.1: European Social Survey. ° INFRA-2010-1.1.2: Survey of Health, Ageing and Retirement in

Europe. ° INFRA-2010-1.1.3: European Social Science Data Archives and

remote access to Official Statistics. ° INFRA-2010-1.1.4: Archives for Historical research. ° INFRA-2010-1.1.5: Towards a European Research Infrastructure

for Modelling & Methodologies. ° INFRA-2010-1.1.6: Research Infrastructures for the study of

Combination of

Collaborative projects and Coordination and Support Actions (CP-

CSA)

1 The Director-General responsible may delay this deadline by up to two months. 2 The final budget of the call may vary by up to 10% of the total value of the call and any repartition of the call

budget may also vary by up to 10% of the total value of the indicated budget for the call. 3 Under the condition that the preliminary draft budget for 2010 is adopted without modifications by the

budgetary authority.


Europe and globalization.

Life Sciences

° INFRA-2010-1.1.7: Plant genetic Resources Centres. ° INFRA-2010-1.1.8: Bio-NMR facilities. ° INFRA-2010-1.1.9: Non-human primate centres. ° INFRA-2010-1.1.10: Animal genetic Resources Centres. ° INFRA-2010-1.1.11: Aquaculture research facilities. ° INFRA-2010-1.1.12: Large-scale bio-banks for clinical and

epidemiological studies. ° INFRA-2010-1.1.13: Facilities for high throughput DNA

sequencing and human genotyping. ° INFRA-2010-1.1.14: High throughput facilities for proteome

analysis. ° INFRA-2010-1.1.15: Good Manufacturing Practices (GMP)

facilities for advanced gene and cell therapy research.

Environmental Sciences

° INFRA-2010-1.1.16: Research Infrastructures for Atmospheric Research.

° INFRA-2010-1.1.17: Sites and experimental platforms for long-term ecosystem research.

° INFRA-2010-1.1.18: Research Infrastructures for native seed conservation.

° INFRA-2010-1.1.19: Research Infrastructures for Polar research. ° INFRA-2010-1.1.20: Research Infrastructures for Coastal

Research, including for Integrated Coastal Zone Management and Planning.

° INFRA-2010-1.1.21: Research Infrastructures for water resource observation, water resource management, hydrological observation.

Energy

° INFRA-2010-1.1.22: Research Infrastructures for Solar Energy: Photovoltaic Power.

° INFRA-2010-1.1.23: Research Infrastructures for offshore renewable energy devices: ocean-, current-, wave- and wind energy.

° INFRA-2010-1.1.24: Infrastructures for research on biomass conversion and biorefinery.

Engineering

° INFRA-2010-1.1.25: Research Infrastructures and services for engineering and improved production processes.

° INFRA-2010-1.1.26: Research Infrastructures for experimental hydraulic research.

° INFRA-2010-1.1.27: Research Infrastructures for earthquake

Combination of Collaborative projects and Coordination and Support Actions (CP-CSA)


hazard.

Mathematics, Computer-related Sciences, Data

° INFRA-2010-1.1.28: Infrastructures for Mathematics and its interfaces with science, technology and society at large.

° INFRA-2010-1.1.29: Advanced Digital Visualisation Facilities.

Analytical Facilities

° INFRA-2010-1.1.30: Research Infrastructure for advanced spectroscopy, scattering/diffraction and imaging of materials.

° INFRA-2010-1.1.31: Research Infrastructures for processing, analysis and characterisation (physico-chemical properties, health and environmental impact) of engineered nanomaterials, nanoparticles and nanostructures.

Physics, Astronomy, Nuclear- and Particle Physics

° INFRA-2010-1.1.32: Research Infrastructures for Nuclear Physics. ° INFRA-2010-1.1.33: Detectors for future accelerators. ° INFRA-2010-1.1.34: Research Infrastructures for dark matter

search, neutrinos, gravitational waves. ° INFRA-2010-1.1.35: Research Infrastructures for high energy

astrophysics.


1.2 Support to new research infrastructures

1.2.2 Construction of new infrastructures (or major upgrades) - preparatory phase

° INFRA-2010-2.2.1: EISCAT_3D Upgrade (Upgrade of the EISCAT facility for ionospheric and space weather research).

° INFRA-2010-2.2.2: EPOS (Infrastructure for the study of tectonics and Earth surface dynamics).

° INFRA-2010-2.2.3:SIAEOS (Upgrade of the Svalbard Integrated Arctic Earth Observing System).

° INFRA-2010-2.2.4:ECCSEL (European Carbon Dioxide and Storage Laboratory).

° INFRA-2010-2.2.5: EMBRC (European marine biological resource centre).

° INFRA-2010-2.2.6: EU-OPENSCREEN (European Infrastructure of Open Screening Platforms for chemical biology).

° INFRA-2010-2.2.7: EuroBioImaging (Research infrastructure for imaging technologies in biological and biomedical sciences).

° INFRA-2010-2.2.8: High Security BLS4 Laboratory (Upgrade of the High Security Laboratories for the study of level 4 pathogens).

° INFRA-2010-2.2.9: EMFL (European Magnetic Field Laboratory) ° INFRA-2010-2.2.10: CTA (Cherenkov Telescope Array for

Gamma-ray astronomy). ° INFRA-2010-2.2.11: One project in the European strategy for

Combination of

Collaborative projects and Coordination and Support Actions (CP-

CSA)

particle physics (CERN Council)

1.3 Support to policy development and programme implementation

1.3 INFRA-2010-3.1: ERA-NET supporting cooperation for research infrastructures in all S&T fields

Coordination and Support

Actions (CSA-CA)

1.3 INFRA-2010-3.2: Studies, conferences and coordination actions supporting policy development, including international cooperation, in all S&T fields.

Coordination and Support

Actions (CSA-CA or

CSA-SA) • Eligibility conditions:

- The general eligibility criteria are set out in Annex 2 of this work programme and in the guide for applicants. Please note that the completeness criterion also includes that part B of the proposal shall be readable, accessible and printable.

- The minimum number of participating legal entities required, for all funding schemes, is set out in the Rules for Participation and presented in the table below.

Funding scheme Minimum conditions


At least 3 independent legal entities, each of which is established in a MS or AC, and no two of which are established in the same MS or AC.

Coordination and Support Actions -coordinating action (CSA-CA)

At least 3 independent legal entities, each of which is established in a MS or AC, and no two of which are established in the same MS or AC.

Coordination and Support Actions -supporting action (CSA-SA)

At least 1 independent legal entity

- For activity 1.1.1 (Integrating Activities) the following additional eligibility criteria

apply in this call: o the maximum EC funding requested must not exceed EUR 10 million, o for each proposal, all three categories of activities (networking activities, trans-

national access and/or service activities, and joint research activities) are mandatory.

- For activity 1.2.2 (Construction of new infrastructures - preparatory phase) the following additional eligibility criteria apply in this call: o the maximum EC funding requested must not exceed EUR 6 million.

- For ERA-NET proposals (topic INFRA-2010-3.1) the minimum number of participants is three independent legal entities which finance or manage publicly funded national or regional programmes. Each of these must be established in a different Member State or Associated country.

- Only information provided in part A of the proposal will be used to determine whether the proposal is eligible with respect to budget thresholds and/or minimum number of eligible participants.

• Evaluation procedure:

- The evaluation criteria and scoring scheme are set out in Annex 2 of the work programme.

- Proposal page limits: Applicants must ensure that proposals conform to the page limits and layout given in the Guide for Applicants, and in the proposal part B template available through the EPSS. The Commission will instruct the experts to disregard any pages exceeding these limits. The minimum font size is 11. All margins (top, bottom, left, right) should be at least 15 mm (not including any footers or headers).

- A one stage submission procedure will be followed.

- Experts will carry out the individual evaluation of proposals remotely.

- The procedure for prioritising proposals with equal scores is described below. It will be applied successively for every group of ex aequo proposals requiring prioritisation, starting with the highest scored group, and continuing in descending order: (i) Proposals that address topics not otherwise covered by more highly-rated proposals,

will be considered to have the highest priority. (ii) These proposals will themselves be prioritised according to the scores they have

been awarded for the criterion impact. If necessary, any further prioritisation will be based on other appropriate characteristics, to be decided by the panel, related to the contribution of the proposal to the European Research Area and/or general objectives mentioned in the work programme.

(iii) The method described in (ii) will then be applied to the remaining ex aequos in the group.

- Specific selection and award criteria for activities 1.1.1 and 1.2.2 are set out in section VI.2 and VI.3, respectively, replacing those of annex 2 to the Capacities work programme.

- For the evaluation of ERA-NET (topic INFRA-2010-3.1) the general criteria applicable to Coordination and Support Actions given in Annex 2 are supplemented by the following sub-criteria: 1. Scientific and/or technological excellence - Quality of coordination (Threshold 3/5)

• The management should be supported by a suitable governance structure involving the participating organisations at an appropriate level.

2. Quality and efficiency of the implementation (Threshold 3/5) • In reference to the applicable work programme, does the proposed ERA-NET

action pool the necessary resources between national programmes and the Community and does it represent the most appropriate type of public funding for this pre-defined area?

3. Potential impact (Threshold 3/5)

• The participants should be the key actors within their national or regional research systems.

• The ERA-NET activities should lay the foundations for a durable cooperation between the partners involved.

• Is there a clearly identified and agreed European added value through a variable geometry approach?

- A reserve list may be produced of projects that pass the evaluation but fall below the available budget in case additional budget becomes available.

• Indicative timetable: - Evaluation results: estimated to be available within some 4 months after the closure

date; - Grant Agreement signature: it is estimated that the first grant agreements related to this

call will come into force before the end of 2010.

• Consortia agreements: Participants in activities 1.1.1 and 1.2.2 are required to conclude a consortium agreement.

• The forms of grant and maximum reimbursement rates which will be offered are specified

in Annex 3 to the Capacities work programme. • Particular requirements for participation, evaluation and implementation:

- For activity 1.1.1 (Integrating Activities) the project duration would be 4 years maximum with no more than EUR 2.5 million of requested EC funding in average per year. In general, each topic corresponds to a given class of research infrastructures and it is not expected to receive competing proposals under the same topic. Around 20 projects are expected to be selected under this activity.

- For activity 1.2.2 (Construction of new infrastructures (or major upgrades) - preparatory phase) the project duration would be 48 months maximum. The requested EC contribution would be in the range of EUR 3 million to 6 million.

- For the topic "3.1 ERA-NET", the project duration is expected to be 24 to 36 months with a requested EC contribution in the range EUR 1 million to 2 million.

- ERA-NETs are aimed at developing and strengthening the cooperation and coordination of national and/or regional programmes and/or policy actions for research infrastructures. Activities eligible for funding should correspond to: (1) information exchange, (2) Definition and preparation of joint activities and (3) Implementation of joint activities (for more details on these activities please look at Annex 4 of the 2010 "Cooperation" Work Programme).

Eligible partners for ERA-NET actions are: • Programme owners: typically national ministries/regional authorities responsible for

defining, financing or managing research programmes carried out at national or regional level.

• Programme 'managers' (such as research councils or funding agencies) or other national or regional organisations that implement research programmes under the supervision of the programme owners.

• Programme owners (typically national ministries/regional authorities) which do not have a running or fully fledged research programme at the moment of submitting an

ERA-NET proposal, but which are planning, and have committed, to set up such a programme, are also eligible if their participation is well justified and adds value to the overall programme coordination. As such, countries or regions which have less diverse research programmes (in particular new Member States and candidate Associated countries) will find their involvement in the ERA-NET scheme greatly facilitated.

Please note that research organisations or universities which are not programme owners or managers are not eligible partners for ERA-NET actions. In addition, other private legal entities (e.g. charities) which manage research programmes may participate if their participation is well justified and adds value to the overall programme coordination. Sole participants (as referred to in Article 10 of the Rules for Participation) may be eligible if the above-mentioned specific criteria for eligible ERA-NET partners are respected. A sole participant shall explicitly indicate which of his 'members' forming a sole legal entity is either a programme owner or programme manager in the proposed action and indicate for these members, the respective national/regional programmes which are at the disposal of the proposed ERA-NET action.

- For the topic "3.2 Studies, conferences..." the project duration is expected to be 12 to 24 months with a requested EC contribution in the range of EUR 0,2 million to 1 million .

- In the context of developing synergies and complementarities between FP7 and cohesion policy, projects applicants are encouraged to check the operational programme for Structural Funds applicable in their regions and to contact the related managing authorities for complementary or alternative support (see: http://ec.europa.eu/regional_policy/atlas2007/index_en.htm).

• Use of flat rates for subsistence costs: In accordance with Annex 3 of this work programme, this call provides for the possibility to use flat rates to cover subsistence costs incurred by beneficiaries during travel carried out within grants for indirect actions. For further information, see the relevant Guides for Applicants for this call. The applicable flat rates are available at the following website: http://cordis.europa.eu/fp7/find-doc_en.html under 'Guidance documents/Flat rates for daily allowances'.

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