Forecast：To be the first choice of our customer

Marketing Theory： Renovation, Quality, Service

Managing Philosophy

Character：To be a good person before doing a good job

Consciousness： To restrict on yourself before restricting on others

Cultivation： To educate and train someone before asking him to work for you

Mission：To be the leadership of the fluoride industry in the world, never stop

creating for achieving the quality life of humankind.

Beijing Zhejiang Yongtai

Electronic Research Center

Zhejiang Yongtai Technology Co., LtdHeadquarters, fluoride intermediate, Advanced pharmaceutical intermediate, Agrochemical intermediate, Mono liquid crystal and intermediate

Zhejiang New SiteAdvanced intermediateGMP standard

Binhai Yongtai Pharmaceutical and Chemcial Co., Ltd.Subsidiary company, fluoride intermediate, big scale of pharmaceutical intermediate and agrochemical intermediate

Joint Laboratory of Zhejiang University

Joint Laboratory of Zhejiang University of Technology

Zhejiang Yongtai Research Center

Overview

Yongtai was founded as a 100% private company in 1999 by Mr. He Renbao and Mrs. Wang Yingmei.

Focus on fluoro-aromatic chemistry for pharmaceutical,agrochemical and liquid crystal intermediates

From USD90,000.00 , the registered capital reachedUSD36.5 million.

4 main manufacturing sites in Zhejiang, Jiangsu and Shangdong which covers an area of 7.1 million Sq feet (650,000 Sq meters).

Around 1200 employees, college level 20%. 750 Operators

On 22nd, Dec, 2009, Yongtai became a public company in Shenzhen Stock Exchange. Code 002326.

Holding 26% shares of Jiangxi Fuxiang Pharmaceutical Co., Ltd In 2010 which produce antibiotic API.

The company start to integrate from the starting raw materials to end products. In 2011, Yongtai bought the CaF2 mine in Hainan Province.

Zhejiang Headquarters

Zhejiang Headquarters

Overview

Organization Chart

Zhejiang SiteTotal 40,000 m2, Chemical plant for intermediateEmployee: 500

1 Purification plant , 9 synthesis plants

Total Reaction Volume: 400 m3

Two distillation plants and total 53 columns (Theoretical plates from 40-100)

Film evaporator, Fix bed Reactor

Low temperature -90 ℃

High temperature + 330 ℃.

Reaction pressure: 60bars (6.0 MPa)

Plant 1- Zhejiang Site

Plant 2- Zhejiang New Site

Total 120,000Sqm and investment is USD100Million

GMP starting raw material and Advanced intermediateEmployee: 280

8 Synthesis plants100,000 class Clean Room for refining-drying-packing2 Pilot plants1 Hydrogenation plants

Reaction Volume: 705 m3 at presentTotal will be 1500 m3 after installation completing

Hydrogenation Capacity: 3000L*4, SS(6.0MPa )200L* 1, SS (1.0MPa)

Low temperature -90 ℃High temperature + 250 ℃.

Reaction pressure: 6.0MPa

Plant 3- Jiangsu SiteTotal 90,000M2 , Chemical plant Employee: 380

Total Reaction Volume: 700 m3

High efficient continuous fractionalColumn (Theoretical plates 300)

Nitration : 10000mt/annual

Friedel-Crafts reaction capacity : 3000mt /annual

Grignard and Suzuki-coupling: 200mt/annual

50 skilled and innovative chemists and researchers in labs for new products R&D and process optimization.

Joint labs in Zhejiang University of Technology and Zhejiang University for new technology cooperation

Beijing Kedi Yongcheng Techology Co., Ltd, research liquid crystal material and other electronic material.

Headquarters’ Research center, provincial High-New technical research center. Focus on aromatic fluoride intermediate R&D and industrialization transfer team for lab production to commercial scale.

Licensed Scifinder, Reaxy are available for R&D

Multi purpose pilot plant from 20liters to 1000liters by stainless steel and glass lining reactors. It can provide the service from kg to hundreds kg.

Custom synthesis ability by undertaking multi step chemistry involving alarge variety of reaction.

R&D Status

DQCGC-MS, Agilent 7890A+5975CLC-MS, Agilent 1260+6120ICP-MS, Agilent 7700X,IR, Shimadzu, Affinity-1,Polar meter, Rudolph AOTOPOL VDSC, waters Q20Parallel reaction system, H.E.LStability study, 3MHS-GC, GC, HPLC

Safety evaluationChemical Stability screeningThermal Screening Unit, H.E.L, TS”Accelerating Rate Calorimeter, H.E.L., PHiTEC

Process Control & Scale up dataSIMULAR Reaction Calorimeter, H.E.L

R&D Instrument R&D Patents & Awards

Authorized Patent 9

Application Patent 20

Significant Technology Achievement Transfer Project of Ministry of Industry & Information Technology of PRC

1

TFT Transformation of Industrialization project of National Development & Reform Commission

1

National Torch Plan 3

Provincial Significant Technology Project 2

1st Prize of Petroleum & Chemical Industry Association 1

Provincial Technology Prize 3

Reaction Type (Example)

Fluorination Halogen exchange, Schiemann reaction,

Halogenation Bromination, Chlorination

Photo-Chlorination/Bromination Chlorination/Bromination on aliphatic side-chain

Diazotization Sandmeyer Reaction, Gattermann Diazonium Salt Substitution reaction, Diazonium salt Hydrolysis

Organometallic Grignard, n-BuLi

Coupling Reaction Suzuki Coupling

Wittig Alkene

Acylation Friedel-Crafts

Ammonolysis Amino substitution

Alkylation C, O & N alkylation

Reduction Catalytic Hydrogenation, Metal Hydride

Nitration Aromatic Compounds

Esterification Phenols & carboxylic acid esters

R&D Reaction Type

Custom Synthesis Workflow

Customer enquiry

Secrecy agreement

Feasibility study (7~10days)

Time schedule to customer

Process evaluation (30~60days in YT)

Bench scale Trials (30~60days in YT )

Quality validation (30 days in Customer)

Pilot scale Trials (60~90days in YT)

Evaluation of cost estimation

Customer approval(30~60days in Customer)

Facility expansion to commercial size (3~6 months)

Staff and Quality system training

Manufacturing & Supply

R&D Custom Synthesis Procedure

Intellectual Protection

Establish project team including R&D, DQC, Pilot Plant, Equipment, EHS

Use code for project and key raw material

Split big project to different teams

Report only to project manager

Sign confidential agreement with each employee

R&D Custom Synthesis Procedure

Cooperation Type

Technical package Transfer

Synthesis Route Scaling up Development

Synthesis Route Design

Quality Study

Process design in Commercial

Project management

Establish project team & project manager with dedicated R&D, DQC, Q&A, Raw material scouring, Engineering, Pilot scaling up, EHS.

Establish milestone schedule

Weekly report to project manager or update to the customer

Quality study following each step, establish test method & IPC

Safety study following each step

Lab report evaluation by R&D, Engineering, Q&A, EHS, Sales and Financing before pilot

Pilot report with yield, quality, deviation, change, summarize for commercialization

HAZOP by EHS for commercial facility

ISO9001

GMP (ICH Q7)

QA 15 members and QC 42 members

Quality System

GMP System

Facility & Equipment System

Production System

Material System

Quality Control System

Quality System

Packing & labeling System

Achieved ISO14001 in 2005

Achieved OHSAS18001 in 2009, Sep.

E.H.S

Environmental protectionHealth protectionWork and process safety (HAZOP)Meet national and international EHS regulationsOperate as a responsible corporate citizenProduct stewardship safetyEmergency managementTransportation safetyContinuous improvement

We are focusing on

Business / Turnover

The turnover increased over 10 times in 8 years from 2000.In 2005, Jiangsu site put into production.In 2007, increased capacity of pharmaceutical intermediate in Jiangsu siteIn 2011, the new Zhejiang new site put into production.Custom Synthesis Business 30%

0

20

40

60

80

100

120

2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

Million USD

Business / Products ApplicationApplication in 2011

Pharmaceutical61%

Agrochemical27%

LCD11%

MaterialsChemical

1%

Pharmaceutical Agrochemical LCD Materials Chemical

Business / Market

Welcome To YongtaiAn Idea of Solution

Welcome To YongtaiAn Idea of Solution