following our way through the cardiac cycle:. step by step…
TRANSCRIPT
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Following our way through the Cardiac Cycle:
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Step by step…
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Atria and ventricles at
rest
Atrial Systole: 20% of
ventricular filling
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Early ventricular contraction Obtain first heart sound: AV valves close “lub”
EDV
Isolvolumic ventricular contraction
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Ventricular Ejection
Our second heart sound:
semilunar valves close
“dup”
ESV
Isovolumetric relaxation
Ventricular relaxation
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We’re back to atrial and ventricular relaxation
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Wiggers Diagram
Ausculation
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Can we measure how much blood your heart pumps?
CO=SV X Heart Rate
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What determines our stroke volume?
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Stroke volume influenced by
Length of muscle fiber
contractility
Frank-Starling Law(length of muscle fiber)
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Contractility influence by Norepinephrine
Drugs: in the news today! digitalis
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Chapter 15 Blood Flow
Blood Pressure and Control of blood pressure
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Picture 15-3
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Then, how then does blood from your extremities get back to heart from these low pressure veins?
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Skeletal and respiratory pumps
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Varicose Vein Disorders
Spider VeinsDr. Berman
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Measurements of blood pressure
•Systolic between 90 and 135 mmHg
Diastolic between 50 and 90 mmHg
NORMAL BP RANGES
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1. Pulse pressure Systolic pressure-Diastolic pressure
measures strength of pressure wave
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2. MEAN ARTERIAL PRESSURE MAP=1/3 Pulse Pressure + Diastolic pressure
MAP provides a single value that does not show aall the changes of arterial pressure.
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Blood Pressure Day 1 Day 2
120/90 160/70
Now by calculating the mean arterial pressure, on which day is blood flow greatest to the tissues?
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Local Controllers of Blood pressure
Myogenic autoregulation
Paracrines and smooth muscle
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Chemical affects on our blood vessels
Norepinepherine Serotonin
NO Histamine Epinephrine
Vasocontriction
Vasodilation
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Migraines: inappropriate vasodilation
Sumatriptan Serotonin agonist
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Affect of some paracrines Active hyperemia
Reactive hyperemia
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Coordination of blood pressure Control
Baroreceptors stretch
Action potentials to CNS
ANS
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