8/2/2019 Finals 2nd Semester Notes

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Brenda LozanoSickle Cell Disease Notes

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http://www.nhlbi.nih.gov/health/health-topics/topics/sca/treatment.html

http://www.webmd.com/a-to-z-guides/sickle-cell-disease-treatment-overview

http://www.sicklecellmemphis.org/sickle-cell-fast-facts.html http://jama.ama-

assn.org/content/281/18/1768.full.pdf

http ://www.seattlecca.org/di seases/sickle-cell-disease-facts.cfm

http://www.ehow.com/how_2

Notes:*What is a Sickle Cell Disease?-Is a disorder of blood caused by inherited abnormalhemoglobin.

~ Another way to call Sickle Cell Disease is SickleCell Anemia.*How is Sickle Cell Disease inherited?-Is inherited as an autosomal recessive condition whereas an autosomal dominant trait.*How is Sickle Cell Disease diagnosed?-A simple blood test, done at any time during a personslifespan, can detect whether he or she has Sicklehemoglobin. However, early diagnosis is veryimportant.*What are the symptoms & treatments of SickleCell Disease?-Fever, swelling & inflammation of hands &/ or feet,pain crises, fatigue & anemia, jaundice (Yellowishdiscoloration of the skin & eyes), vision problems, lung& heart injury, & other features.- The tissues with impired circulation suffer damagefrom lack of oxygen.*How is Sickle Cell Disease treated?-Sickle Cell Disease has no widely available cure.However, treatments can help relieves symptoms &treat complications.-Early diagnosis of Sickle Cell Disease is critical so thatchildren who have the disease can receive propertreatment.

*Important Facts.-People with Sickle Cell Disease should avoid contactwith anyone suspected of having fifth disease, whichcaused by parvovirus. Parvovirus can cause totemporarily stop making blood, a server life-threatening problem with Sickle Cell Disease.-Early treatment is very important & may includeoxygen, pain medicines, antibiotics, & transfusions.-Routine lab test to monitor health include: ~ Complete blood count.

~ Urine test.~ Test to monitor the functioning of organs.

-Sickle Cell patients rarely lived past their 20s & morethan half of those who suffered from it died inchildhood.- There is no cure for the disorder.- Antibiotics help prevent infections I infant, &painkillers, intravenous fluids & breathing oxygen helpto treat episodes of pain.-Some of the hemoglobin forms ion, red- like structuresthat cause the red blood cells to be Sickle-shaped &

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8/2/2019 Finals 2nd Semester Notes

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Brenda LozanoSickle Cell Disease Notes

091958_prevent-sickle-cell-anemia.html

stiff.- These can clog mall blood vessels, preventing someorgans or tissues from receiving enough oxygen.-2.5 million Americans have the genetic trait fordisease.-70,000 people in US have Sickle Cell Disease-About 1,000 children are born with Sickle Cell Diseasein country each year.

CONTINUE.-Sickle Disease, red blood cells starts out normal, but if they are stressed they become curved, hard, & sticky.

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