CUTICON-KARNATAKA-2018th

9 State conference of theIADVL KARNATAKA

www.cuticonkn2018mysuru.com

Organized by

with

Mysore Dermatology Society

IN ASSOCIATION

IADVL-KARNATAKA BRANCH.

Date:Septemberth th

28 to 30 , 2018

Venue:

Mysuru

Silent shoresResorts & Spa

From the Desk of Organizing Committee

Dear all,

th The 9 Annual Conference of Indian Association of Dermatologists, Venereologists th thand Leprologists [IADVL] - Karnataka branch will be held from 28 to 30 September 2018 ,

at the historic city of Mysuru. The theme of the conference is “IMMUNODERMATOLOGY-

BENCH TO BEDSIDE”.

“UNDERSTANDING - CLINICAL IMMUNODERMATOLOGY”, a preconference, th continuation medical education programme will be organized on 28 SEPTEMBER 2018.

In 1981, Prof Mark V Dhal published- “Clinical Immunodermatology”, the first of its

kind, single author book to understand – inflammatory skin disease. In its early days-

psoriasis vulgaris was still considered an epidermal pathology. The pemphigus group was

in its early stage of dissection. Later, HIV, entered the arena of STI and immunodeficiency

was discussed more often than before. Diagnostic Immunofluorescence became common

place.

The only drug we had then to manage autoimmune disease were corticosteroids.

Later methotrexate, azathioprine, cyclosporine and FK506 (Tacrolimus) offered more

therapeutic options.

Immunopharmacology, now, is the new kid on the block. Biologics are used more

often to manage, autoiummune bullous disease, psoriasis vulgaris and urticaria.

Be it a post-graduate, practitioners or professors, we have our gaps in our

understanding of this intimidating subject. We thought we shall learn during this

conference- more of clinical immunodermatology- from bench to bedside.

Also for your family, we have the whole Mysuru- The Ambavilas Palace, the world's

visited monument, India's biggest “walk through Aviary” at Karanji lake, St. Philomenas ndchurch, Asia's 2 largest church and Trin- Trin, wherein you can hire a bicycle for local

commuting.

Welcome to Mysuru. For academic retreat or social retreat.

Co-Chairman & President, MDS

Dr. Surendran K A K

Organizing secretary

Dr. B L Nanjundaswamy

Organizing Chairman

Dr. Y M Shivakumar

Executive committee- IADVL- National

Executive committee-IADVL- Karnataka.

Vice Presidents.

Dr Jagadish Sakhiya / Dr Mukesh Girdhar

Vice- presidents.Dr Umashankar N. / Dr Shashikumar. B.M.

Honorary Secretary GeneralDr Umashankar N

Honorary TreasurerDr Shashikumar. B.M.

Honorary Secretary GeneralDr Manjunatha. R

Honorary TreasurerDr Savitha. A. S.

President

Dr. M. Ramesh Bhat

President Elect

Dr. P. Narasimha Rao

Immediate Past President

Dr. Yogesh Marfatia

PresidentDr Chandrashekar. B.S.

President ElectDr Sathish Pai. B.

Immediate Past President.Dr Arun C. Inamadhar.

Honorary Joint secretaries.Dr Dinesh Kumar Devaraj / Dr Prashant Palwade.

Honorary Joint Gen Secretaries-Dr Manjunath Hulmani / Dr Jayanth D.P.

CUTICON -KN- 2018 - ORGANIZING TEAM

IADVL- Karnataka

President: Dr. B.S. Chandrashekar

Secretary: Dr. Manjunatha R.

Mysore Dermatology Society

President: Dr. Surendran K.A.K.

Secretary: Dr. Bangaru. H

CUTICON-KN-2018- MYSURU TEAM

PatronsDr. B D Sathyanarayana

Dr. Mallikarjuna MDr. Hanumanthappa HDr. Jayadev Betkerur

Scientific committee :Dr Veeranna SDr Omprakash H M

Finance committee :Dr Amar Lal K Dr Hemanth KumarDr S Ravi, Dr Belliappa

Registration committee :Dr Raghavendra K RDr Sathish S

Catering committee :Dr Harish M RDr Shashi Kumar B M

Reception committee :Dr Sridhar K SDr Ashwini P KDr Lavanya

Cultural committeeDr Raju JDr Purushotham S M

Accommodation committeeDr Raghavendra HDr Krishna Kumar B

Dr Dayanand T RTransport committee

AdvisersDr. Kushalappa.P.A

Dr. Ramanand Kumar. B

Organizing chairman : Dr. Y.M. Shivakumar

Dr. Surendran K A KOrganizing Co-Chairman :

Dr B L NanjundaswamyOrganizing secretary :

Dr Prasanna. P

Dr Bangaru. H.

Organizing Joint secretary :

Treasurer/ Web site editor : Dr D P Jayanth

Cuticon KN-2018 – Scientific sessions

1. Immunity and Mind.

2. Skin immunity and commensal Microbiome.

CME overview

Conference overview

Understanding clinical Immunodermatology

Preconference continuing medical education theme is- understanding- clinical

Immunodermatology. This will be interactive, clinical case based one day programme. Not too

much theory.

Immunodermatology-Bench to bedside.

In Greece, apart from Acropolis , the most visited place is- Delphi. The famous -Temple of

Apollo is situated in Delphi. In this temple is inscribed a famous letter in gold- “ΛΝΩΘΙЕαΓΤΟΝ”.

This means

“know thyself”.

This letter, though short, is profound with meaning. Different persons can interpret this

differently, and for this scientific congress – we wanted to say “know your immunity”.

Dr John Sarno, a senior New York city based physician, had observed in his busy practice, that

some cases of Primary hypertension despite medications failed to respond. He had ruled out

secondary causes, life style and drug compliance issues.

He had also noted that, some of his cases of -Intervertebral disc prolapse, had severe sensory

symptoms in the lower limbs. But the CT scan showed very minimal disc herniation. Upon

surgery this patients continued to have pain. He wondered why? .

He pooled these cases , on his free day and starting spending more time—Just talking to them.

Within weeks the hypertension was controlled and the symptoms of disc herniation resolved

without additional drugs. He released their pent up emotions which, had manifested as

somatic diseases.

Dr Sarno – now had an answer—THE DIVIDED MIND. We have a subconscious mind, which acts

on the conscious mind and produces various diseases.

At CUTICON-KN 2018-We shall see how the mind affects immunity.

Biofeedback, hypnosis and meditation. How these affect the immunity ? How will they help

in managing- wart, lichen simplex chronicus.

th thIn the late 18 and early 19 century , surgeons were in great demand in England. The large

intestine was thought to be a cesspool and not required for dignified living. Many elite people

underwent colectomy. Later these people's health started deteriorating. Wondering why?

The normal commensal, of intestine, has local and distant immunological action. When this is

disturbed we have- locally colitis and distantly- arthritis and encephalomyelitis.

In 2012, Naik et al, published a seminal paper in SCIENCE journal – establishing the important

role of commensal bacteria on skin , in producing skin local immunity. When this commensal

is disturbed by- antibacterial soap or oral antibiotics we may have diseases. Atopic dermatitis,

psoriasis, hidradenitis suppurativa , acne vulgaris are few diseases wherein there is local

immune dysregulation.

At cuticon KN 2018- we shall see how the local microbiome affects immunity.

Tuning skin immunity by skin commensal bacteria. Is it time to banish antibacterial soap?

In 1965, Dr Simpson RE , a general practitioner , published a paper after nearly 16 years of

observation of cases in his family practice. He hypothesized that, chicken pox and Herpes

zoster are caused by the same virus. And Herpes zoster is nothing but reactivation of Varicella

zoster virus from its latency , arising from post root sensory ganglion. A remarkable prophecy ,

before the advent of electron microscopy or serological tests.

But have we dermatologist , asked the question- Why chicken pox does not cause – neuralgia

and only Herpes zoster does ?

Well until we get this answer, we can at least prevent Herpes zoster. In 2017 USA FDA approved,

Shingrix subcutaneous vaccine in prevention of Herpes zoster in individuals above 50 Years. Its

efficacy is more than 90% and duration of protection more than 5 years.

At cuticon KN 2018- we shall learn more above the vaccine .

Prevention of Herpes Zoster by Vaccination.

Pemphigus vulgaris , an autoimmune acquired immunobullous disorder, has well defined

diagnostic tools. But the cornerstone of management – systemic corticosteroids with or

without adjuvant immunosuppressants , has unpredictable remission, not the forget

iatrogenic diseases induced by these agents. The 2017 , British association of dermatologist

guidelines , questions the above therapeutic approach. They are suggested that a treatment

naïve, new patient should be administered, anti CD20 drugs first and not corticosteroid with or

without adjuvant immunosuppressants.

Rituximab is the most commonly administered intravenous, biologics for pemphigus. Various

regimens have been practiced. 500mg IV once in fortnight or 1000mg IV once in fortnight with

or without oral corticosteroids or immunosuppressants.

At cuticon KN 2018, we will exchange notes about administering Rituximab for pemphigus.

How we manage Pemphigus vulgaris using Rituximab?

Also ethics of using biologics in pemphigus.

In your practice , you might have come across patients with recurrent lower limb cellulitis.

These patients have- long saphenous varicosity, or have undergone long saphenous vein

harvesting or stripping surgery. On examination they may have intertrigo or xerosis of skin or

minor trauma leading to cellulitis.

The contralateral leg will also have intertrigo or xerosis but without cellulitis. Why?

This is the local immunocompromised district or zone in relation to Long saphenous vein

territory due to disturbed lymphatics which lie parallel to this vein.

At cuticon KN 2018 , we will examine how to manage this cellulitis.

3.Boosting innate immunity against Varicella zoster virus.

4. Immunomodulation in treating Pemphigus by biologics.

5. Immunocompromised district in lower limb

Recurrent lymphangitic cellulitis syndrome: A quintessential example of an

immunocompromised district

Alopecia areata has a prevalence of 2 % of population. Nearly 30% of alopecia areata present as

totalis and universalis. The reported cure rate of totalis and universalis is less than 10%.

Alopecia areata, occurs due to shortening of anagen phase of hair cycle with prolonged telogen

phase and also due to loss of immune privilege of hair follicle.

Diphenylcyclopropenone is considered the most effective topical immunotherapy.

In 2016 , a plant extract in ointment base was tried on scalp and nearly 96 % patients had vellous

hair with 43 % having full terminal hair.

At cuticon KN 2018, we shall keep an open mind and see how the immunological privilege is

restored in follicle.

A novel ointment for treatment of Alopecia totalis and universalis.

Also we shall probe the role of Janus kinase inhibitor- Tofacitinib in managing refractory

alopecia patients.

Norway saw eradication of leprosy , decades before the onset of MDT . But despite free MDT

and good case detection and surveillance , India contributes nearly 60 % of worlds leprosy new

cases i.e, 1,27,326. WHO in its ambitious plan- 2016-2020- wants zero disease, disability,

transmission and discrimination.

At cuticon KN 2018 , our speakers will dissect and see if the 2016- 2010 vision of WHO is

achievable.

Global vision 2016-2020 -WHO

Immunology of lepra reaction.

How does one manage medically fore foot and hind foot ulcers?

A developing country like CUBA was declared as the first country to have eliminated mother to

child transmission of HIV and syphilis in 2015. Even Thailand, Bermuda were added to this list

in Dec 2017.

Resource poor countries with political instability have achieved the unthinkable. Where does

India stand here. There is a talk of ending AIDS BY 2030. Is it achievable.

At cuticon KN 2018, we shall discuss the above topic.

Mother to child Transmission of HIV and syphilis.

Immune reconstitution syndrome and HIV.

Para-phenylenediamine is ubiquitous. A standard self-testing for 24 hours sometimes does not

pick up cases of allergic contact dermatitis. So then how does one prove the diagnosis. Next,

sunscreen are used more than before. They are stand alone products or added in

cosmeceuticals.

6. Disrupted immunological privilege of hair follicle and alopecia areata.

7. Immunology and Leprosy.

8. Immunology and sexually transmitted diseases.

9. Immunology and allergic contact dermatitis.

Newer UV/IR/VISIBLE filters are discovered. These products can produce contact or photo

contact allergic contact dermatitis.

At cuticon KN 2018, we shall discuss-

Clinical and experimental aspects of allergic contact dermatitis to para-phenylenediamine,

Sunscreen allergy and its investigation

Past one year the dermatology fraternity of Karnataka , for the first time, was galvanized and did

have a say in KPME ACT. The act has got gazette notification. What does this mean to a IADVL

member?

Centre is trying to dissolve MCI and reconstitute National medical council. We don't have the

final verdict at the time of our programme publication.

One has to realize that already there are some new central guidelines-

v How should the prescription paper be ?

v How does one give a medical certificate?

v Relationship with pharmaceutical company?

v Maintenance of medical records.

Professional indemnity , social security are the other topics of concern for us.

At CUTICON KN-2018, we shall discuss- KPME ACT, NMC and DVL trust matters.

The other topics doing rounds are

Newer guidelines in managing - ACNE and Androgenetic alopecia. How all the

practitioners can be on the same page of therapy for a given case.

Rosacea and innate immunity. How does doxycycline modulate immunity?

Filariasis, and common chronic dermatosis- how does complementary therapy affect

immunity and clinical outcome?

Psoriasis vulgaris and immunomodulation.

Biologics- where are we heading?

What's new in allergy.

Immunotherapy in warts

Aprelimast in other disease - immunological basis.

Immune dichotomy in leprosy. Spectral concept of various cutaneous diseases.

Immunbusters in alternatives medicines - role and controversies.

Biologicals vs biosimilars

10. IADVL forum

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CUTICONKN 2018 is your scientific feast.Any topic pertaining to -Immunodermatology,

which we have missed could be mailed.We shall try to accommodate.

You can reach us atscientific@cuticonkn2018mysuru.com

ABSTRACT SUBMISSION

www. cuticonkn2018mysuru.comscientific@cuticonkn2018mysuru.com

Silent shores Resort and spa

ACCOMMODATION

Key pointsv Abstract submission is online only.v Only IADVL members, registered for conference, will have access for online submission.v Type of papers one can submit- 1. Free papers 2. Award papers3. E posters 4. Dissertation.For details of online submission and guidelines of abstract preparation, please visit the

portal—

For queries on abstract submission, mail at-

85-87, BEML Road, Off Hunsur Road, Hootagalli.

Mysuru, Karnataka- 570018.

Phone numbers- +91 821 2402930/31/33

Mobile- +91 9686 666692/95.

Email- reservations@silentshoresresort.com

Website- www. Silentshoresresort.com

1. Regalis - 11Km from venue. 0821-242626, 9448067750

2. Quorum - 11km from venue.0821-42927777,9620274620

3. Radisson blue - 14km from venue. 0821-17101234, 18001080333

4. Pai vista - 14km from venue. 0821-2521111, 99456154

5. Hotel Sandesh the Prince - 14km from Venue. 0821-2436777

6. Ruchi the Prince - 4km from venue. 0821-2413072

Conference Venue

You can reach us at : cuticonkn2018mysuru@gmail.comOr only in case of emergency, call

Dr Sathish. S.+91 99001303150

Dr Raghavendra. K. R.+91 7353936087

September 28 2018

September 29 and September 30 2018

May 31 2018

July 31 2018

February 1 2018 to June 30 2018

Continuing Medical Education

Conference

Early Bird registration last date

Conference registration with late fee

Abstraction submission dates

IMPORTANT DATES

Why Mysuru for unwinding?

Twice bagged the honor of being the cleanest city of India.

World's most visited monument- Amba palace or Mysore palace.

India's biggest “Walk Through Aviary” at Karanji lake.

St Philomenas church the Asia's second largest Church.

Mysore Zoo, second best in Asia.Mysore Pak, Mysore Dosa - local delicacies.

Why Mysuru for academics?

First f ree school of country

completing 184 years – Maharaja's

High school.

First university of state- Mysore

university completing 100 years.

Mysore Medical College- First

Medical College of Karnataka state,

established in 1924.

First TB hospital of India.

Government Ayurvedic Medical College, one of the oldest in country.