Expertise for H2020 2019 calls

Lorem Ipsum Dolor

About the National Institute of Chemistry - NIC

12 Departments

309 Employees

144 Researchers with PhD

74 PhD students

26% revenues from marketing activities

In expanding knowledge of chemistry and associated studies In transferring knowledge to younger generations In applying newly acquired knowledge to industry

12 departments

D01 Department of Theoretical Chemistry

D10 Department of Materials Chemistry

D13 Department of Catalysis and Chemical Reaction Engineering

D06 Department of Food Chemistry

D12 Department of Synthetic Biology and

Immunology

D15 Slovenian NMR Centre

D16 Center for Validation

Technologies and Analytics

D11 Department of Molecular Biology and

Nanobiotechnology

D05 Department of Environmental Sciences and Engineering

D04 Department of Analytical Chemistry

D09 Department of Inorganic Chemistry

and Technology

D07 Department of Polymer Chemistry

and Technology

PREGL RESEARCH CENTER

9 Mio EUR 3800 m2

Finished 2013

800 MHz NMR spectrometer National NMR Centre (CERIC/ERIC) AR-STEM (Jeol, ARM 200 CF) Supra 35 VP EM with EDX analysis Confocal microscopy (Leica TCS WLL SMD platform) High performance computing cluster

Our knowledge is your opportunity

Date: 03. 10. 2018

Pressing challenges

Health

Energy

Environment Food

Climate

Responsible Research and Development

Life sciences

Materials research

Chemical engineering

and catalysis

Theoretical chemistry

Analytical chemistry

Chemistry and related disciplines

Excelent research...

...solving problems

projects- 2018

33 EU projects

20 H2020

4 Interreg

65 national funding

5 ERA NET

1 ERC Adg

2 EIT-

Climate KIC

1 NATO SPS

Call DT-NMBP-03-2020: Open Innovation Test Beds for nano enabled surfaces and membranes(IA)

Cooperation opportunities

• We have expertise and state of the art equipment for characterisation of materials structure and chemical composition at atomic scale.

• Probe Cs-corrected STEM with EELS and EDXS attachments in combination with dedicated sample holders enables beside quantitative high-resolution dark, bright and annular bright-field imaging also TEM and STEM tomography, material science cryo-microscopy and heating-biasing in situ experiments.

• We have also extended experience in FEG-SEM microscopy and microanalysis and FIB tomography and TEM lamella preparation.

Call NMBP-15-2019: Safe by design, from science to regulation: metrics and main sectors (RIA)

Cooperation opportunities

• We are able to build a system for evaluation of toxic properties of nanomaterials, which inludes in vitro data and physico-chemical properties of nanomaterials. We performe chemometrical analysis of proteomics data obtained in in vitro measurements of different cells types treated with different nanomaterials (multi-walled carbon nanotubes, TiO2 nanobelts and nano-silver). Proteomics are recorded from cells treated under different conditions (doses and time of exposure). Applying different chemometrical tools we identified proteins, which are highly disturbed under specific conditions regarding the nanoparticle type or the time of exposure.

• • This information can be used to identify adverse biological

pathways, or together with phsico-chemical propertis as descriptors in nano-QSAR models.

Call NMBP-15-2019: Safe by design, from science to regulation: metrics and main sectors (RIA)

Cooperation opportunities

At the early stage of nanomaterials development process the Laboratory of Cheminformatics can model the physico-chemical properties and biological effect assessment of nanomaterials based on expirience in EU projects for evaluation toxicological properties of chemicals for regulatory uses and participating in establishment of VEGA platform. The Laboratory can develop new models upon request or offer predictions with in-house developed in silico models for nanomaterials:

– Fullerene derivatives (FD) – computational approach for evaluation of fuleren derivatives binding activity based on quantum chemical calculations, quantitative structure activity relationships (QSAR) models and protein-ligand docking simulations of 170 fullerene derivatives nanoparticles with 1117 disease-related biological targets (proteins); binding affinity is considered dependent on the functional groups or structural alert (SA) of FDs and descriptors correlated with binding activity of FDs nanoparticles are applied in prediction.

– Nanosized metal oxides (MeOx) – computational approach based on neural network algorithm for cytotoxicity evaluation of various metal oxides (covered all MeOx from the periodic system).

Call SFS-04-2019-2020: Integrated health approaches and alternatives to pesticide use (RIA)

Cooperation opportunities

• National Institute of Chemistry has expertise for studying plant pathogens at the molecular level. This includes plant cell membrane damaging toxins as well as Potato Virus Y.

• We use methods of molecular biology, protein and lipid biochemistry, biophysics, bioinformatics, cell biology and structural biology.

• We are interested in details of molecular interactions to understand the pathogen-host interplay and thus the mechanism of pathogenesis. This is important basis for development of tools for plant protection.

Call LC-NMBP-32-2019: Smart materials, systems and structures for energy harvesting (RIA)

Cooperation opportunities

NIC develops and delivers characterisation for: – protective coatings for various metals/alloys(sol-gel, on the basis of various

polymers (fluoropolymers, polyurethanes, epoxy, acrylates …); – smart coatings (spectrally selective, high solar absorptivity, absorber coatings

for Concentrated Solar Power, hydrophobic, oleophobic, antistatic, antifauling, self-replenising, flame retardant, cool coatings);

– organic synthesis of special bio-based additives as cross linkers or bulk resin modifiers in order to improve hydrophobicity, enable self-replenishing function, improve flame retardant property, cooling effect (patent AT510371) resulted in prolonged longevity and reduced biofouling activity.

– organic synthesis and characterization of ionic liquids as electrolytes for DSSC or battery application

– life time assessment of absorber coating for concentrated solar power… – development of carbon based (graphene, graphene oxide) additives for

anticorrosion application – fluides rheology optimization and characterization – IR and Raman analysis of smart materials…

Call CE-NMBP-25-2019: Photocatalytic synthesis (RIA) Cooperation opportunities

• We offer design and optimisation of solar photoreactors including modelling phase. Coupling various heterogeneous catalytic processes. Department of Catalysis and Chemical Reaction Engineering has experience in photocatalytic reactor design, multi-scale process modelling and engineering, especially with regard to photocatalytic water splitting, CO2 reduction and the selective oxidation reactions to (speciality) chemicals. We can also aid scale-up.

• While we also design catalysts ourselves, we prefer to be involved in the field of chemical reactor engineering, overall process optimisation, as well as the modelling at various operation scales (atom to plant) – in-house catalysis expertise is a benefit though.

• Department of Catalysis and Chemical Reaction Engineering is primarily invested in chemical (process) engineering, reactor and unit operation design and construction, as well as multi-scale process modelling. The Department topics foremost include carbon dioxide and natural gas conversion, hydrogen and fuel cell technologies, biomass valorisation to bio-based compounds, and (bio)pharmaceutical processes.

Call DT-NMBP-19-2019: Advanced materials for additive manufacturing (IA)

Cooperation opportunities

National Institute of Chemistry develops and delivers characterisation for:

– polymer synthesis/modification/characterization – mechanical recycling of GFR polyester/acrylate (here

we can activate major composite producers that have significant quantities of unutilized scrap)

– nanocellulose preparation and modification – graphene nanocomposites – nanocomposite processing (micro extrusion and micro

injection moulding) – self reinforcing thermoplastic composites

Call NMBP-21-2020: Custom-made biological scaffolds for specific tissue regeneration and repair (RIA)

Cooperation opportunities

• National Institute of Chemistry offers the synthesis of porous materials from synthetic / natural polymers, whereby the open porous structures with porosities up to 95%, low skeletal density (< 0.1 g/cm3), versatile functionality, and relatively high specific surface area (100 – 1500 m2/g) are obtained.

• Beside synthesis of non-degradable polymers based on radical polymerization of acrylic and styrenic monomers we are well versed in controlled synthesis of different (bio)degradable and biocompatible polymers, including ring-opening polymerizations to prepare polyesters as well as synthetic polypeptides specifically suited for biomedical applications.

• Synthetic polypeptides that combine the modular nature of synthetic polymers together with biocompatibility, biodegradability and high functionality of natural polymers are one of the most promising candidates for preparation of custom-made biological scaffolds for specific tissue regeneration and repair, since they can be fine-tuned to meet demands for specific tissue cells. We are currently developing novel synthetic polypeptide-based porous scaffolds, which present a new generation of biocompatible, biodegradable macroporous scaffolds that have desired surface functionality providing cell adhesive properties, with 3D-interconnected porous morphology, providing pathways for migration and proliferation of cells as well as vascularization.

Call DT-NMBP-08-2019: Real time nano-characterisation technologies (RIA)

Cooperation opportunities

• Electrochemistry and associated electrochemical (bio)sensorics offer almost unsurpassable opportunities for creating a great variety of sensing approaches and tools, due to continuous emergence of novel (nano)materials, (nano)technologies, and due to unique convenience of electrode surface modification and further miniaturization, and minimal or unnecessariness of sample pre-treatment.

• The virtue of electroanalysis is certainly relatively simple, portable and non-expensive instrumentation which we also possess. Electrochemical sensors and microsensor devices can operate individually or can be a part of more complex and integrated sensing systems.

• We can deliver electrochemical sensors, i.e. their development/preparation, miniaturization and application in more challenging environments (e.g. in-vivo measurement of neurotransmitters, gas sensing). A special attention is paid to the development of advanced sensing (composite) coatings/membranes encompassing inorganic and organic materials, e.g. thin metal films (Bi, Sb), carbon-based nanomaterials, (functionalized) polymers, ionic liquids, etc. aimed at providing enhanced sensitivity, selectivity, (semi)permeability, and chemical and/or mechanical stability of sensors.

• Miniaturization of sensing surfaces is another research area in which our Department has substantial expertise, e.g. preparation of carbon fiber microelectrodes and their subsequent surface modification together with the development of electrode assemblies which would allow convenient detection of, e.g. selected gaseous pollutants in museums and galleries, trace metal ions in environment, ...

• In the forthcoming project our research would be focused on the development and preparation of novel electrochemical sensors primarily for measuring selected volatile organic compounds (VOCs), such as selected aldehydes, ketones and phenols, etc.

Call MG-2-6-2019: Moving freight by Water: sustainable infrastructure and innovative Vessels (RIA)

Cooperation opportunities

• One of requirements of the call is environmental performance. National Institute of Chemistry can deliver development of advanced analytical methodologies for a wide range of applications.In general, we cover 3 main scientific areas: atmospheric chemistry with a focus on ambient aerosol , elemental imaging and chemical characterization and electroanalytical chemistry and sensors. We are specialized in trace analysis of complex matrices using inductively coupled plasma mass spectrometry (elemental composition of bulk solution/digested samples or solid-sample microanalysis if coupled to laser ablation; (LA)-ICP-MS, ion chromatography (anions and cations; IC), liquid chromatography tandem triple quadrupole mass spectrometry (molecular characterization; LC-MS/MS).

• We are specialists in ambient particulate matter (PM), including the impact on the ecosystem and health. Besides the abovementioned departmental instrumentation, the following specialized instrumentation and corresponding expertise is offered: scanning mobility particle sizer (online measurements of nanoparticle number size distribution, 4–1000 nm; SMPS), 10-stage Berner cascade impactor (PM sample collection for offline elemental and/or molecular characterization, 10 stages within 38 nm–15.6 m), state-of-the-art aethalometers (online black and brown carbon measurements, in collaboration with the industrial partner).

Call LC-MG-1-9-2019: Upgrading transport infrastructure in order to monitor noise and emissions (RIA)

Cooperation opportunities

• NIC is specialised in measurements of ambient particulate matter (PM), including the impact on the ecosystem and health. Besides the abovementioned departmental instrumentation corresponding expertise is offered: scanning mobility particle sizer (online measurements of nanoparticle number size distribution, 4–1000 nm; SMPS), 10-stage Berner cascade impactor (PM sample collection for offline elemental and/or molecular characterization, 10 stages within 38 nm–15.6), state-of-the-art aethalometers (online black and brown carbon measurements, in collaboration with the industrial partner). Additionally, we also possess expertise in gas chromatography tandem mass spectrometry analysis (GC-MS instrument).

We deliver (1) development of (micro)electrodes and electrochemical (gas)sensors, (2) development of sensing materials and study of electrode interfacial processes, (3) development of electrochemical methodologies and application studies.

National Institute of Chemistry

Hajdrihova 19 1001 Ljubljana, Slovenia

Webpage: www.ki.si

e-mail: project.office@ki.si Phone: 00386 (1) 476 0498

Fax: 00386 (1) 476 03 00

Contacts