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Evaluation of Different Wireless Communication Systems For Intracortical Prosthesis Cortivis Report Deliverable D4 By INESC-ID

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  • Evaluation of Different Wireless Communication Systems

    For Intracortical Prosthesis

    Cortivis Report

    Deliverable D4

    By INESC-ID

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    2

    Contributions to this report

    This report includes written contributions and results of research work of: Prof. Gonçalo Tavares,

    Prof. José Gerald, Prof. Moisés Piedade and Engº Ricardo Ribeiro (PhD student). The report also

    includes work developed by the undergraduate students Ricardo, Elísio and Manuel.

    The reported work benefit with the helpful discussions in the periodical meetings, realized within the

    SIPS research group, aiming the architecture definition of the intracortical prosthesis and the design of

    VLSI circuits. It includes suggestions of Prof. Leonel de Sousa, Profª Beatriz Borges, Prof. Jorge

    Fernandes, Prof. Marcelino Santos, Prof. Pedro Santos and Prof. Carlos Martins.

    The work also benefits with the information given by all CORTIVIS partners.

  • CORTIVIS

    3

    Architecture of the intracortical prosthesis system

    This document reports some of the work developed by INESC in the first year of the CORTIVIS

    project, namely in the design of the intracortical prosthesis. The block diagram of the intracortical

    prosthesis system under development is shown in Fig.1 below. The system is divided in two parts: the

    primary and the secondary system. The former is located outside the human body and the later is

    designed to be placed inside the human body (not necessarily inside the head). Two radio frequency

    (RF) data links connect these systems: a forward link which transmits data from the primary to the

    secondary system and a backward link which operates in the reverse direction. Both links may operate

    simultaneously (full-duplex mode) or in half-duplex mode. It is yet to decide whether need for full-

    duplex operation is required. The forward link transmits a power/data signal modulated carrier in the 4

    -16 MHz frequency range at a data bit rate up to 1 Mbps using ASK (Amplitude Shift Keying) or FSK

    (Frequency Shift Keying) modulation. After demodulation and frame disassembly, useful data is

    forward to the electrode stimulator. This bit rate is enough to drive about 1000 implanted electrodes.

    The secondary power and main system clock are derived from the forward link signal. In the opposite

    direction BPSK (Binary Phase Shift Keying) will be used to modulate a carrier at a bit rate up to 16

    kbps which suffices for maintenance purposes. The coupling between the primary and the secondary

    system is done using a RF low coupling transformer.

    Fig.1- Architecture of the intracortical prosthesis system.

    This report is organized in four sections, each addressing the following material:

    • Section 1 deals with the design of the coupling transformer. Several problems regarding the

    magnetic coupling between primary and secondary coils were identified. Among these, the

    most important is the high variability of the coupling, which depends on misalignment,

    distance and load. To overcome these problems, a number of transformer design solutions were

    FILTER

    DATACONTROLLER

    AMPLIFIERPOWERMODULATOR

    CLOCK

    DEMODULATOR AGC

    Dat

    a

    Di

    PC

    POWERAMPLIFIER

    DEMODULATOR

    RF

    RF

    DATAPROCESSING

    RF LINK

    CONTROLCIRCUIT

    POWER SUPPLY

    GENERATOR

    CLOCKRECOVERY

    DATAPROCESSING

    Adress

    Command

    ELECTRODESSTIMULATOR

    Data

    Data

    Electrodes

    Command

    MODULATOR

    Enable

    PRIMARY SYSTEMSECONDARY SYSTEM

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    4

    built and tested. The necessary transformer models were also developed and their accuracy

    evaluated.

    • Section 2 presents the forward link design and is divided in several subsections each devoted to

    one particular functional block. Section 2.1 treats the problem of carrier recovery. The RF

    transceiver, using both ASK and FSK modulation schemes, has been simulated at the

    functional level, first and at circuit level afterwards. The previously developed RF transformer

    models were included in the simulation model. Several simulations using a carrier frequency of

    8 MHz and a data rate of 1 Mbps were performed in order to evaluate the transmitter

    performance under different conditions, such as different transmission channels, modulation

    level, filters type and filter bandwidths, and transmitter/receiver architectures. This work is

    presented in Sections 2.2 and 2.3. In Section 2.4 a comparison between ASK ad FSK is

    presented; it justifies the final decision to use FSK instead of ASK. Section 2.5 presents the

    design of the bit synchronizer used in the receiver. Finally, some problems and solutions

    regarding the power delivery are presented in Section 2.6.

    • Section 3 presents the backward link design which is still in an initial developing phase.

    • The final conclusions and future work perspectives are presented in Section 4.

    1 Transformer design

    1.1 Introduction

    The electronic circuits in the cortical prosthesis developed in the CORTIVIS project need to be

    wireless power supplied by an external system, see Fig. 1.1.

    The cortical prosthesis is provided with a bidirectional data link to the outside system. Both power and

    data will be transferred by a radio frequency (RF) transformer composed by an external coil and an

    internal one placed inside the prosthesis. The coils may be separated about 1 to 3 cm, see Fig.1.2. This

    transformer has a very low coupling coefficient between the two coils, so, at the first analysis, it is

    expected to have low power transfer efficiency. This will be contested in this document, by adoption

    of some circuit techniques and RF coil design rules.

  • CORTIVIS

    5

    The expected bit rate of the communication between the external system and the prosthesis is about

    1Mbps. To support this bit rate a carrier frequency in the range 4 MHz to 20 MHz is required. In the

    following design examples, we will use 8 MHz for the carrier frequency.

    DATA ANDPOWER

    TRANSMITTERRECEIVER

    RECEIVER INTERNALTRANSMITTER

    DATACONTROLLER

    Dat

    a

    Cortivis

    High LevellCONTROLLER

    POWER SUPPLYGENERATOR

    DATAPROCESSING

    STATE MONITOR

    Dat

    a

    RF

    RF

    VARIABLES

    ELECTRODESSTIMULATOR

    STATESENSORS

    RF LINK Fig. 1.2- Detail of RF link to intracortical electrodes.

    1.2 RF transformer model

    Without any prior estimate of the prosthesis minimum size, we made the hypothesis of using a

    maximum coil diameter of 3 cm (coil will be placed in the border of the prosthesis). Smaller coils will

    be very sensitive to geometric distance variance between position of internal and external coils. Coils

    must be placed in a parallel-resonant circuit with an integrated small capacitor (smaller than 20 pF)

    which defines the carrier frequency of a band-pass filter. The required self inductance is 160 µH; this

    can be obtained by 50 turns of copper wire (0.2 mm diameter) wound in 8 layers over a 3 cm diameter

    air form (Rayner formula for multilayer cylindrical coils, see Annex 1.), which results in the values of

    L1 given in Table1.1.

    Fig. 1.1- RF link to intracortical electrodes

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    6

    Experimental measurement of the coil reveal the model represented in Fig.1.3a), with a very high self

    capacitance, Cp = C and high AC resistance R, compared to the DC resistance RDC (R ≅ 32 × RDC).

    This is due to the skin effect, see Table 1.1. This inductor can not be used because the self-resonance

    frequency, fp, is lower than the required carrier frequency (at 8 MHz the inductor is capacitive); this is

    due to the high self-capacitance value.

    Table 1.1- Experimental results for RF coils.

    Reducing the inductance lowers the number of turns and layers of the coil, but the self-capacitance

    does not lower significantly. To reduce self-capacitance and AC resistance, planar coils realized in an

    appropriate substrate will be the next step to follow in the project.

    LR

    Cp

    a)

    b)

    λ11R11

    n:1λ22 R22

    c)

    λ11R11 nLΜ

    λ'22= n2λ22

    R'22=n2R22

    n:1

    v2vMv1

    Cp1

    Cp1 C'p2=Cp2 / n2

    Cp2

    Fig. 1.3- RF transformer model.

    However, inductors L5 and L6, realized with a single wire layer, having a self resonance frequency

    above the desired carrier frequency, are appropriate to build a prototype of an RF transformer, and in

    the following will be named L1 (primary coil with n1 wire turns) and L2 (secondary coil with n2 wire

    turns), respectively. Inductors L1 and L2 placed side by side at a distance d, realize an RF transformer.

  • CORTIVIS

    7

    The electrical current I in L1 generates a total magnetic field flux L1× I, but due to the coil physical

    separation only a fraction of this flux is coupled with L2, representing the mutual induction LM, and

    consequently induces a voltage on L2. The other portion of magnetic flux, which is λ11 × I (dispersion

    flux), does not contribute to induce voltage on L2. Anyway L1 = λ11 + LM and L2 = λ22 + LM.

    The RF transformer model, represented in Fig.1.3b), takes into account the flux dispersion, skin effect

    resistances and self capacitances of both inductors, L1 and L2. The ideal transformer takes into account

    the ratio n of number of turns of L1 e L2 (n = n1 /n2). In our case n = 1. The circuit in Fig.1.3c)

    represents the RF transformer model referred to the primary side

    1.3 Study of transformer coupling

    The coupling coefficient between primary and secondary coils is defined by k = LM(L1L2)-1/2 . By

    inspection of Fig.1.3c) it can be concluded that the low value of LM (high λ11) originates a great

    Fig.1.4 – Jig for RF transformer testing.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    8

    reduction of voltage vM and v2 and, as a consequence, very low voltage transfer efficiency between

    primary and secondary coil is expected. Using the empirical formula included in the annex 1, the

    coupling coefficient for different separation distances between primary and secondary coils was

    calculated. In order to measure the coupling coefficient, an experimental test jig was constructed. It´s

    photo is shown in Fig.1.4.

    Both theoretical and experimental results obtained for the transformer made with inductors L5 and L6

    (Table 1.1), are represented in Fig.1.5, where a good value agreement for k was achieved, specially in

    the distance region of 1 cm to 3 cm, covering the distances that will be used in CORTIVIS

    intracortical prosthesis.

    The open circuit voltage transfer function of the RF transformer, using the model of Fig.1.3c), built

    with parameters L5 and L6 given in Table 1.1, and values of coupling coefficient variable between 0.1

    and 0.4, was simulated in the SPICE program. The results obtained are shown in Fig.1.6.

    0 0.5 1 1.5 2 2.5 3 3.50

    0.05

    0.1

    0.15

    0.2

    0.25

    0.3

    0.35

    K

    distancia (centimetros)

    Fig.1.5 – Theoretical and experimental (dot points) RF transformer coupling coefficient.

  • CORTIVIS

    9

    The experimental results obtained by measuring the transformer, see Fig. 1.7, agree very well with the

    simulated ones, validating the model used.

    104 105 106 107 108-60

    -50

    -40

    -30

    -20

    -10

    0

    10

    20

    frequencia (Hz)

    Gan

    ho (d

    B)

    Fig. 1.7 – Experimental voltage transfer ratios for distances of 0 cm, 1 cm, 2 cm and 3 cm

    between primary and secondary coils with RL = ∞.

    1.4 Frequency response of the loaded RF transformer

    The low value of k means L1 ≅ λ11>> LM and L2 ≅ λ22 > LM. There are big reactive voltage drops in λ11

    and λ22, which reduces the voltage ratio v2/v1 (see Fig.1.3c) between primary and secondary coil.

    However, these voltage drops can be compensated by opposite voltages developed in resonant series

    Frequency

    10KHz 30KHz 100KHz 300KHz 1.0MHz 3.0MHz 10MHz 30MHz 100MHzvdb(rl:2)-vdb(r4:2)

    -60

    -40

    -20

    -0

    20

    40

    Fig. 1.6 – SPICE simulation of voltage transfer ratio of RF transformer with RL

    = ∞, for different values of k. (k = 0.1, 0.2, 0.3 and 0.4).

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    10

    capacitors CA and CB, placed between the transformer and the source generator (RS and vS) and also

    with load RL, respectively, see Fig.1.8.

    λ11R11nLΜ

    λ'22=n2λ22

    R'22= n2R22

    n:1

    v2vMv1

    Cp1 C'p2= Cp2 /n2

    CBCA

    vP vS RLvS

    RS

    Fig. 1.8 – Complete model of the RF coupling link between external system and

    intracortical prosthesis.

    This is a complete model of the RF coupling link usable both for power transfer and bidirectional data

    transmission between the external system and intracortical prosthesis. To obtain the frequency

    response of the communication channel and the power transmission efficiency from the generator vS to

    the load RL, the circuit shown in Fig.1.8 was simulated on SPICE, for different values of RL around

    the expected value correspondent to the prosthesis power consumption of 125 mW ( 5 V @ 25 mA)..

    The results in Fig.1.9 show the expected frequency response and its variability with load conditions.

    These are fundamental results showing that an expected power of 200 mW, increasing vS, can be

    obtained for supplying the intracortical prosthesis circuitry and also showing the expected data

    channel frequency response to be taken in account in the design of the data communication system.

    Frequency

    2MHz 4MHz 6MHz 8MHz 10MHz 12MHzvdb(r1:2)-vdb(r3:1)

    -40.0

    -20.0

    -0.0

    -59.9

    15.0

    Fig. 1. 9 – Frequency response of the data communication channel for different transformer

    coupling factor k and RL = 200 Ω. (k = 0.1, 0.2, 0.3 and 0.4).

  • CORTIVIS

    11

    Frequency

    2MHz 3MHz 4MHz 5MHz 6MHz 7MHz 8MHz 9MHz 10MHz 11MHz 12MHzVdb(R1:2)-Vdb(R3:1)

    -60

    -40

    -20

    0

    20

    Fig. 1. 9 – Frequency response of the data communication channel for different load resistances

    RL and a transformer coupling factor of 0.2. (RL = 100 Ω, 300 Ω, 500 Ω, 700 Ω and 900 Ω).

    2 Forward link design

    2.1 Carrier recovery

    2.1.1 Introduction

    The purpose of this receiver block is to recover a clock signal from the incoming RF signal, to serve as

    a master system clock. In order not to compromise system performance, it is of fundamental

    importance that this recovered clock be of the highest quality possible. The simulation results for the

    ASK modulation scheme indicated the need of PLLs (Phase Lock Loops) in both the received data and

    the master clock circuitry, in order to achieve precise frequency (no significant jitter) signals. Also, the

    ASK modulation scheme presents a significant problem, which is to be highly dependent on the

    channel amplitude response (which is unknown and may vary in time). Results also show that the FSK

    scheme is more robust to the main problem which is the high variability of the RF channel.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    12

    2.1.2 SPICE simulations

    The carrier recovery circuit has been simulated at the circuit level using SPICE. The actual circuit

    simply a charge-pump Phase Locked Loop (PLL) which is represented in Fig.2.1.1.

    g2vb

    g1va

    500p

    1k

    vc

    500p

    '1'

    va

    vb

    1Meg

    1Meg

    5v

    g4vc

    g3vc

    1MegD Q

    CLK R

    D Q

    CLK R

    D Q

    CLK R

    '1''1'

    g1=g2=1m g3=26u g4=37,2uVout (160)

    Vin (8)

    Fig.2.1.1- Electrical diagram of the Charge-pump Phase Locked Loop (PLL).

    In Fig.2.1.2 we present simulation results regarding the carrier recovery circuit operating with an ASK

    modulated signal.

    Fig.2.1.2– Carrier recovery circuit operation: input ASK signal, error signal and

    output PLL signal.

    After a transient period of about 1.5µs, which is roughly one and a half bit, the PLL error signal

    stabilizes providing a clock signal to be used as the master system clock. Since, at the transmitter, the

    carrier frequency is synchronized with the data, the recovered master clock is also synchronized with

    the received data (the actual phase difference is unknown but will be properly adjusted by the bit

    synchronizer described in Section 2.5).

    Time

    0s 0.5us 1.0us 1.5us 2.0us 2.5us 3.0us 3.5us 4.0us 4.5us v(160) v(132) v(8)

    -2.0V

    0V

    2.0V

    4.0V

    5.0V

    ASK signal (PLL in)

    VCO out (recoverd clock)

    error signal vc(132)

  • CORTIVIS

    13

    The carrier recovery results for operation from a FSK information signal are given in Fig.2.1.3.

    Fig.2.1.3– Carrier recovery circuit operation with FSK signal.

    The PLL used is the same although with different parameters. It can be seen that a clean recovered

    clock is present at the PLL VCO output. The most important conclusion from these results is that the

    carrier recovery signal processing requirement is the same regardless of the modulation employed

    (ASK or FSK).

    2.2 ASK modulation

    2.2.1 Introduction

    To evaluate the modulation scheme used in the RF link, it was tested, by its simplicity, robustness and

    reliability, a binary ASK (Amplitude Shift Keying) transmitter, also called OOK (On-Off Keying)

    when one of the amplitudes is chosen to be zero. However, the need of obtaining the receiver power

    supply from the received signal, makes it undesirable to have zero energy received signal periods.

    Thus, the OOK modulation was abandoned and an amplitude modulation with data enveloping was

    adopted. Non coherent detection was used in order to avoid the need for a local carrier at the receiver,

    resulting in a much simpler demodulator. A low value (17.6%) of percentage modulation was assumed

    (carrier amplitude with values 0.7 or 1). The percentage modulation was chosen taking in

    consideration 2 factors: (i) the need of the most energetic signal always present at the receiver (the

    receiver is inside the patient head) and (ii) the distortion caused by the coupling transformer included

    in the transmission path.

    Time

    2.0us 3.0us 4.0us 5.0us 6.0us 1.2us V(8) V(84)

    -5.0V

    0V

    5.0V

    FSK signal

    Recovered clockV(83) V(19)

    2.15V

    2.20V

    2.25V

    SEL>> Transmitted data

    PLL error signal

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    14

    2.2.2 SIMULINK evaluation

    The RF transmitter using an ASK modulation scheme was simulated at the functional level first and at

    circuit level afterwards using respectively Matlab and Spice simulators. In the simulations the

    transformer models previously developed were included. The simulations have shown that the ASK

    modulation index should be lower than 30% in order to avoid signal degradation and the subsequent

    need for equalization.

    A transmission system was simulated by means of simulation program Matlab with Simulink, from

    MathWorks. The carrier frequency used was 8 MHz for a data rate of 1 Mbps. Several simulations

    were performed in order to evaluate the transmitter performance under different conditions, such as

    transmission channels, percentages of modulation, filters bandwidth, and emitter/receiver

    architectures. The main goal was to minimize received data errors and data clock jitter.

    The ASK simulated transmission system is represented in Fig. 2.2.1.

    Fig. 1 – ASK transmission system

    Fig. 2.2.1 – ASK transmission system.

    Emitter

    1 R

    Channel

  • CORTIVIS

    15

    The transmission system is composed of a transmitter, a channel and a receiver. The transmitter

    generates the 17.6 % percentage of modulation amplitude modulated signal. This signal is passed

    through a passband channel before it gets to the receiver. In the receiver, two main tasks are performed

    and tested: (i) to generate the receiver master clock, a high frequency clock with 8 MHz, which is

    obtained from the carrier, and (ii) to recover the data information by means of a noncoherent adaptive

    demodulator. An optimal data signal is also generated at the receiver, in order to compare with the

    adaptive demodulator result. This optimal demodulator uses the knowledge of the channel attenuation,

    which, in a real system, is not usually possible.

    The system allows observing several signals, as for instance, the received data signal. An eye diagram

    of the received data signal can be seen in Fig.2.2.2. This information is relevant, for instance, to decide

    which is the best timing to sample the signal in order to decide about the received bit value.

    a) b)

    c)

    Fig. 2.2.2 – Received data eye diagram. a) low-selective and flat passband channel; b) high-selective and flat passband channel; c) high-selective and non-flat passband channel.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    16

    From Fig.2.2.2 one can see how the received data signal optimal sampling time change with the

    increase of channel selectivity. Also the data signal is very dependent from the amplitude response

    shape, which makes the data discriminator very critical.

    Fig.2.2.3 shows the received carrier zero crossing eye diagram. In this figure, one can see the

    associated jitter caused by the transmission channel. With non-flat passband the amplitude response of

    the received carrier zero crossing present a slightly bigger maximum jitter than with a flat passband.

    Also, the jitter is mainly influenced by the percentage modulation, as can be seen in Fig.2.2.3c) where

    the percentage modulation is now 53.8%.

    a) b)

    c)

    Fig. 2.2.3 – Received carrier zero crossing eye diagram. a) 2 MHz flat passband channel and 17.6% modulation; b) 2 MHz non-flat passband channel and 17.6% modulation; c) 2 MHz flat passband channel and 53.8% modulation.

  • CORTIVIS

    17

    The adaptive discriminator implemented in the receiver is a good solution to track the data signal

    amplitude fluctuations, as can be seen in Fig. 2.2.4. This figure shows the data signal and its estimated

    mean value. One can see the initial transient and the posterior stationary functioning of the adaptive

    Fig. 2.2.4 – Received data adaptive discriminator.

    discriminator in its task to track the data mean value. As the RF channel may vary in time and from

    patient to patient, an adaptive solution is required.

    The simulation results for the ASK modulation scheme indicated the need of PLLs (Phase Lock

    Loops) in both the received data and the master clock circuitry, in order to achieve precise frequency

    (no significant jitter) signals. Also, the ASK modulation scheme presented a relevant problem, which

    is to be highly dependent from the channel amplitude response (which is unknown and may vary in

    time), because of its great dependence from the received signal amplitude, specially the amplitude

    distortion.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    18

    2.2.3 SPICE evaluation

    In this section we present a simulation study of the CORTIVIS forward link using ASK modulation.

    The simulation is performed at circuit level using the program SPICE. The schematic circuit of the

    ASK transmitter, including the RF transformer model, is shown in Fig.2.2.5.

    Fig.2.2.5- SPICE circuit model used for the CORTIVIS ASK transmitter.

    n Fig.2.2.6 we represent the random Non-Return-to-Zero (NRZ) data signal at 1Mbps and the ASK-

    modulated signal with a carrier frequency of 8MHz and a modulation index of 30%, measured at the

    receiver input (v(8) in the schematic of Fig.2.2.5).

    Fig.2.2.6-Waveforms for ASK modulation.

    Vcc10V

    L1

    16uH

    RL 200

    C22

    16.5p

    R15 820

    Cp4.1pF

    Cs 4.1p

    Rs

    50

    L2

    16uH

    R14 1k

    R2

    357 Q1 .

    C11

    412uF

    Q5 .

    Q4 .

    CM

    16.5p

    R16 100

    LM4uH

    R13 500

    R8

    50

    Rp

    50

    LRF 1797.7nH

    Q6 .

    R1 180

    V1

    RANDOM DATA GENERATOR

    T=2us

    F=8MHZ

    V(8) RF TRANSFORMER MODEL

    Time

    0s 5us 10us 15us 20us 25us 30us 35us 40us v(8) v(214)

    -2.0V

    0V

    2.0V

    4.0V NRZ

  • CORTIVIS

    19

    Note the time delay of approximately one bit between the data and the envelope of the modulated

    waveform.

    To recover the data from the ASK signal a noncoherent demodulator is employed. It is implemented

    by an envelope detector and a threshold estimator followed by a comparator.

    Vcc

    1Meg

    1K35k

    100pF

    10k

    10k

    50nF

    Va

    Vb

    ΩASK signalData out

    Fig.2.2.7- ASK noncoherent demodulator.

    The ASK demodulator is depicted in Fig.2.2.7. It consists on two half-wave passive rectifiers followed

    by two lowpass integrating filters with different time constants. The filter producing Vb has a small

    time constant allowing data to pass and cutting harmonic components generated by the rectifier. On

    the other hand, the filter producing Va is designed to have a much lower cutoff frequency as is

    required to estimated the DC component of the signal. Both filter outputs are used by a schmitt-trigger

    comparator to detect the received data. The signal Va acts as a dynamic threshold accounting for

    possible amplitude variations of the received ASK information signal. The simulation results for these

    signals are given in Fig.2.2.8. It should be pointed out that the use of a Schmitt-trigger comparator is

    absolutely necessary. This is due to the fact that still a significant amount of harmonics pass through

    the lowpass filter and appear in Vb as can be clearly seen in this figure.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    20

    Fig.2.2.8- ASK demodulator waveforms: Va is the threshold signal used by the comparator.

    The signal at the comparator output is plotted in Fig.2.2.9 together with the received ASK waveform.

    Again, it is noticeable the delay between the two signals which is due to the signal processing. As can

    be seen by comparing the recovered data with the NRZ data (transmitted data) in Fig.2.2.6, there are

    no data errors (note that the recovered data is complemented).

    Fig.2.2.9- Recovered data from the ASK information signal.

    2.3 FSK modulation

    2.3.1 Introduction

    One of the modulations considered to be used in the RF forward link of the CORTIVIS system is

    binary FSK (Frequency Shift Keying). With this modulation, each bit is assigned a different frequency

    Time

    0s 5us 10us 15us 20us 25us 30us 35us 40us v(8) v(64)

    -2.0V

    0V

    2.0V

    4.0V

    Received ASK waveform

    Recovered data

    Time

    0s 1us 2us 3us 4us 5us 6us 7us 8us 9us 10us v(58) v(54)

    -200mV

    0V

    200mV

    400mV

    600mV

    Vb

    Va

  • CORTIVIS

    21

    deviation from the central carrier frequency which as been set at 8 MHz. The simulation results

    presented here, as well as the theoretical considerations in Section 2.4 lead to the conclusion that this

    modulation will be the best choice for the CORTIVIS RF forward link.

    2.3.2 SIMULINK evaluation

    The system was simulated in Simulink, a component of the MATLAB simulation software, as is

    depicted in Fig.2.3.1.

    In1

    In2

    errorsnum

    error

    error counter

    PLL (XOR)

    datadem odulation

    VCO

    Voltage-Control ledOsci l lator

    T ransportDelay

    Sum Scope

    Relay2

    Relay1

    Out1

    Pseudo Randomdata generator

    Periodogram

    Periodogram

    MuxMux1

    .9

    FrequencyVector Scope1

    FrequencyVector Scope

    0

    Display

    data

    c lock

    sy nc_data

    data_clock

    Data sincronization

    (3 2 2 1 0)

    Constant

    butter

    Channel

    PLL (XOR)

    master clockrecovery

    Data Clock

    TransmiterReceiver

    Fig. 2.3.1 – FSK transmission system simulation.

    The transmitter contains a data generator and a FSK modulator. The modulator was done with a VCO.

    The VCO switches between two carrier signals according to the value of the incoming data bit. The

    carrier frequencies chosen where 8.25MHz for the high bit level and 7.75MHz for the low bit level,

    which is equivalent to a central carrier of 8MHz with an 250KHz frequency deviation. The bit rate is

    1Mbps.

    The FSK modulated signal spectrum, shown in Fig.2.3.2, has the first two local minimums at 7.25

    MHz and 8.75MHz, meaning that most of the signal’s energy is located between those two

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    22

    frequencies. The transmission channel was simulated by a second order Butterworth passband filter

    centered at 8 MHz with a 2 MHz bandwidth. The receiver input signal spectrum is depicted in

    Fig.2.3.3.

    Fig.2.3.2 - Spectrum of the FSK modulated signal.

    Fig.2.3.3 - Spectrum of the signal at the input of the receiver.

    In order to demodulate the FSK signal a broadband phase-locked-loop (PLL, Fig.2.3.4) was used. The

    PLL will follow the frequency of the signal at the input of the receiver and at the lowpass filter output

  • CORTIVIS

    23

    will have the demodulated signal which is then passed trough a discriminator. The discriminator will

    recover the original bit stream. The signals before and after the discriminator can be seen in the second

    plot from the top of Fig.2.3.5. Another PLL, now a narrow-band one, was used to recover a master

    clock with a frequency equal to the central carrier frequency (see Section 2.1). This time we use the

    signal at the output of the PLL’s voltage controlled oscillator (VCO). The master clock and the

    demodulated bit stream were feed to the data synchronization block. This block recovers a clock

    synchronized to the data bit stream. The data bit stream can be observed in the third plot from the top

    of Fig.2.3.5 and the data clock in the fourth plot. As can be observed, the original bit stream is

    successfully recovered. In fact no transmission errors where detected during the simulations performed

    Fig.2.3.5 - Time plot. The top signal is the generated bit stream. Below that is the demodulated signal before and after the discriminator (both overlapped). The last two are the bit stream and the data clock recovered by the data synchronization block.

    3

    2

    1

    VCO

    Fn(s)

    Fd(s)T ransfer Fcn

    Relay1

    Relay

    XOR

    LogicalOperator

    G

    1

    Fig.2.3.4 – Phase-locked-loop (PLL).

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    24

    2.3.3 SPICE evaluation of system using FSK

    In this section we present a simulation study of the CORTIVIS forward link using FSK modulation.

    The simulation is performed at circuit level using the program SPICE. The schematic circuit of the

    FSK transmitter, including the RF transformer model, is shown in Fig.2.3.6.

    Fig.2.3.6- SPICE circuit model used for the CORTIVIS FSK transmitter.

    In Fig.2.3.7 we represent the random Non-Return-to-Zero (NRZ) data signal at 1Mbps and the binary

    FSK-modulated signal with a carrier frequency of 8 MHz and a total frequency deviation of 500 kHz

    (the transmitted frequencies corresponding to the possible bit values are 7.75 MHz and 8.25 MHz),

    measured at the receiver input (v(8) in the schematic of Fig.2.3.6).

    Fig.2.3.7- Waveforms for FSK modulation.

    Note that because the two frequencies are very close, their difference is hardly noticeable in this

    figure.

    LRF 1797.7nH

    RL 200

    R33 3K5

    Rp

    50

    Q1 .

    R32 6k5

    R8

    50

    Vcc10V

    R15 820

    Cp

    4.1pF

    R1 180

    VCO LM4uH

    Q4 .

    L2

    16uH

    R13 500

    C22

    16.5p

    Q5 . R14 1k

    Cs 4.1p

    L1

    16uH

    R16 100

    Rs

    50CM

    16.5p

    R2 357

    V(8)

    Q6 .

    C11

    412uF

    RF TRANSFORMER MODEL

    Time

    2.00us 3.00us 4.00us 5.00us 6.00us 1.27us 6.61us V(19)*10-21.8 V(8)

    -1.00V

    0V

    1.00V

    -1.61V

    1.61V NRZ

    FSK modulated waveform

  • CORTIVIS

    25

    To recover the data from the FSK signal a coherent demodulator is employed. It is implemented by a

    phase locked loop (PLL) similar to the one used to recover the carrier clock (see Section 2.1) and

    represented in Fig.2.1.1. The PLL error signal is then fed to a regenerative comparator similar to the

    one used for ASK detection and represented in Fig.2.2.7. The output of this comparator is the detected

    data.

    The simulation results for these signals are given in Fig.2.3.8.

    Fig.2.3.8- FSK demodulator waveforms.

    As with the ASK receiver, the use of a Schmitt-trigger comparator is necessary. This is due to the fact

    that still a significant amount of harmonics pass through the lowpass PLL filter. The most important

    aspect revealed by these results is that the threshold signal required for detecting the data is fixed, i.e.,

    does not need to be estimated from the incoming RF signal (as was the case with ASK). Therefore, it

    is guaranteed that even with very small signal amplitude the system will operate reliably.

    2.4 ASK vs FSK

    This section presents some theoretical guidelines which were relevant in the decision about the most

    appropriate modulation format for the forward RF link (primary-to-secondary system). The

    modulations which have been considered are binary ASK (Amplitude Shift Keying), binary FSK

    (Frequency Shift Keying) and BPSK (Binary Phase Shift Keying). Together with the results in Sections

    2.2 and 2.3, the following considerations justify the final choice of modulation which is to be FSK in

    the case of the forward link and BPSK for the backward link:

    Time

    1.400us 1.600us 1.800us 2.000us 2.200us 2.400us 2.600us 2.800us 1.239us V(124) V(8)

    -5.0V

    0V

    5.0V

    SEL>>

    Recovered data

    FSK signal

    V(43) v(123)

    1.5V

    2.0V

    2.5V

    PLL error signal Decision threshold level

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    26

    • ASK is better than FSK in terms of carrier (i.e., clock) recovery easiness: with ASK, a fraction

    of the carrier is sent together with the information signal. With FSK, the transmitted spectrum

    does not contain specific energy at the carrier frequency; consequentially, carrier recovery is

    more difficult and requires a separate, narrow-band PLL (Phase Locked Loop). However, since

    the ASK carrier recovery subsystem must also contain some pass-band filtering, it seems that

    the required resources for this task will be the same for both modulations.

    • Both ASK and FSK require the same bandwidth.

    • With a time-invariant, constant gain channel, ASK may be demodulated with a simple non-

    coherent receiver, which is a simply an envelope detector followed by a decision device

    (comparator). Non-coherent detection of binary FSK requires two separate precise-tuned

    bandpass filters and is thus much more complicated. However, coherent demodulation of FSK

    is simple and can be done using a simple PLL. Also, a time-invariant, constant gain channel

    does not seem a reasonable assumption for the intracortical CORTIVIS system.

    • In the case of both RF links in the CORTIVIS system, the channel gain has a high degree of

    uncertainty which translates in high amplitude variations; this is due to the randomness

    associated with the coil relative positions. In order to achieve reliable data detection with ASK,

    it is therefore necessary to have high-efficient gain-monitoring and level-controlling devices.

    This is not the case with FSK for which the receiver front end is insensitive to the amplitude of

    the received signal (within reasonable limits). This is a very strong argument for choosing FSK

    over ASK.

    2.5 Bit Synchronizer

    2.5.1 Introduction

    A digital feedforward symbol synchronizer was developed and implemented in a low power FPGA

    which simplifies the demodulator and can be used in both ASK or FSK demodulation schemes.

    In this section, the development of the CORTIVIS secondary system bit synchronizer is presented

    (from now on, the secondary system will be referred simply as the receiver). The task performed by

    this device is of fundamental importance to establish a proper time reference in the receiver. The

  • CORTIVIS

    27

    positive-going transitions in this reference clock should accurately signal the optimum instants to

    sample and detect the received data bits. The part of the receiver interacting with the bit synchronizer

    is depicted in Fig.2.5.1.

    ASK or FSKDEMODULADOR

    MASTERCLOCK

    RECOVERY

    BIT SYNCHRONIZER

    masterclock

    DATASAMPLER

    data Retimed data

    Data clock

    RF link

    CLK bf N R= ´

    /bR bit s

    bf R=

    time

    Retimed data

    Data clock

    1 0 0 1

    Fig.2.5.1 – Data clock recovery and bit synchronizer.

    The signal received from the primary system (which is referred in this section as the transmitter) is

    used to produce the system master clock, with frequency fT

    N RCLKCLK

    b= = ×1 where R

    Tb b=

    1 is the

    raw bit-rate; this is accomplished by the MASTER CLOCK RECOVERY block using a narrow-band phase-

    locked-loop (PLL). At the present stage of the project, target values being considered are Rb = 1

    Mbit/s and N = 8 samples per bit, corresponding to a RF carrier frequency of 8MHz. The received

    signal is also fed to the data demodulator (binary ASK or FSK modulation), which produces a stream

    of raw data bits, but does not provide any time reference signal, required later for proper data

    detection. The following point is worth noting: since the master clock is derived from the transmitted

    signal and is used to demodulate the data, it follows that the data stream must be synchronized (i.e.,

    frequency-locked) with the master clock; a data clock could therefore be obtained by suitable division

    (by a factor N ) of fCLK . This is because there is no frequency offset between transmitter and

    receiver. Although this is true, the (lead or lag) phase difference between the positive-going clock

    transitions and the optimum time epoch for sampling the data which is the middle time of each bit

    is unknown. The purpose of the bit synchronizer is thus to provide a stable reference clock with

    positive-going transitions signaling the middle of each bit (see the time diagram in Fig.2.5.1).

    Nevertheless, the bit synchronizer which has been developed for this project is also able to track small

    frequency offsets, with acceptable performance.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    28

    As it is seen in Fig.2.5.1, the bit synchronizer has a novel feedforward structure; this avoids the

    annoying loop behavior known as hang-up, typical with feedback synchronizers, which manifests

    itself has an unacceptably long synchronizer acquisition period, compromising receiver operation. In

    summary, the bit synchronizer developed has the following desirable properties:

    1) In the absence of frequency offset between transmitter and receiver (as is the case in this

    application) the recovered clock is jitter-free (neither static nor dynamic phase error).

    2) Has a feedforward structure that avoids the hang-up disabling phenomenon.

    3) Is easily implemented with simple digital logic.

    2.5.2 Synchronizer description

    The working principle of the bit synchronizer is best understood with the aid of the waveforms

    depicted in Fig.2.5.2.

    1/b bT R=

    time

    Masterclock

    0 2bTt +0t

    Raw data

    Fig.2.5.2 – Bit synchronizer waveforms.

    Suppose we have a binary counter being driven with the master clock frequency fCLK ; then, it will

    advance N states within each bit period. If, at time t0 , the counter is in state i then, at time

    t Tb0 2+ , it will have advanced T

    Tf

    RNb

    CLK

    CLK

    b2 2 2= = and be in state i N+

    2 (on average); this is when

    the recovered clock should have a positive transition, marking the middle of the data bit. This

    reasoning justifies the block diagram represented in Fig.2.5.3: the positive-going transition on the

    data signal (Non-Return to Zero, NRZ random data signal) latches the counter state i , at reference

    time t0 , and marks the start of a bit. When the counter reaches the state S iN

    = +2

    , then

    S N N i N N i+ = + =2

    mod ( ) mod and the comparator will signal this event to the final processing

  • CORTIVIS

    29

    block, which in turn samples the raw data and produces a clock pulse synchronized with the master

    clock.

    COUNTER

    clock

    LATCH

    ADDER

    COMPARATOR

    SAMPLER &CLOCK SYNC.

    Q

    Clock

    Retimeddata

    Data

    2N

    mod N

    Masterclock

    Raw data

    2Log N

    bits

    DQ

    A

    B

    A = B

    A

    B

    Dataclock

    Fig.2.5.3 – Conceptual block diagram of the developed bit synchronizer.

    2.5.3 Implementation and results

    The realization of the synchronizer using N = 8 samples per bit is shown in Fig.2.5.4. The J-K

    flip-flops U1-U3, together with the AND gate U4 implement the Log N2 3= bit binary counter; D-

    J

    Q

    Q

    K

    SET

    CLR

    U2

    J

    Q

    Q

    K

    SET

    CLR

    U1

    J

    Q

    Q

    K

    SET

    CLR

    U3

    Q

    QSET

    CLR

    D

    U5

    Q

    QSET

    CLR

    D

    U6

    Q

    QSET

    CLR

    D

    U7

    Q

    QSET

    CLR

    D

    U13

    Raw Data

    Master Clock

    Retimed data

    Data clock

    Note: all SET and CLR inputs are connected to ground (disabled)

    /bR bit s

    CLK bf N R= ´

    Realization with samples/bit8N =

    U9

    U8

    U10

    U11

    U4

    U12

    VCC

    Fig.2.5.4 – Bit synchronizer realization using 8 samples per bit.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    30

    type flip-flops U5-U7 form the data register, latched by the positive transitions on the raw data

    signal.

    Gates U8-U11 form the comparator and U12 synchronizes the comparator output with the master

    clock transition, producing the recovered data clock. Finally, U13 samples the raw data signal with

    this clock signal. Note that the mod N adder in Fig.2.5.3 is implemented by recognizing that the

    result of adding N N2

    mod to any count C may be found by taking C and complementing its

    most significant bit; this is why the second input to U9 in Fig2.5.4 (comparator) is the

    complemented output of U3 (i.e., Q instead of Q ). The implementation has been carried out using

    simple logic circuits.

    The synchronizer has been tested using a random NRZ binary data signal as the raw data input

    and an unsynchronised master clock with no frequency offset and also with a frequency offset

    equal to 5% the raw bit-rate (which was set at Rb = 1 Mbit/s); this situation reflects a worst-case

    operation condition since, as stated early, no frequency offset is expected in the CORTIVIS

    receiver. The resulting eye-pattern diagrams for both the data signal and the recovered data clock

    are presented in Fig.2.5.5 and Fig.2.5.6.

    -0.5 -0.25 0 0.25 0.5-1.5

    -1

    -0.5

    0

    0.5

    1

    1.5

    Am

    plitu

    de

    Raw data (eye pattern)

    -0.5 -0.25 0 0.25 0.5-2

    0

    2

    4

    6Recovered data clock (eye pattern)

    Am

    plitu

    de

    Relative time, t/Tb Fig.2.5.5 – Bit synchronizer performance using 8 samples per bit and a master

    clock frequency with no frequency offset: Rb = 1 Mbit/s and fclk = 8 MHz.

  • CORTIVIS

    31

    In the absence of frequency offset (Fig.2.5.5), the recovered data clock exhibits no jitter and

    the positive-going transitions, occurring at t Tb= ±0 25. , accurately mark the optimum sampling

    instants, at half the bit duration.

    When the master clock has a small frequency offset, the recovered clock will still be

    synchronized to the incoming NRZ data stream but will exhibit some amount of phase noise or jitter

    (Fig.2.5.6). Because only N = 8 clock periods are available in each bit duration (8 samples/bit), the

    synchronizer has an inherent phase error of ± = ±TN

    Tb b2 16

    , so the positive-going transitions will occur

    in a Tb8

    -duration interval around the desired epochs t Tb= ±0 25. . This is quite clear in the bottom eye

    diagram in Figure 6. Nevertheless, it must be pointed that because high amounts of noise are not

    expected in this system (i.e., operation is with a wide open raw data eye diagram), the synchronizer

    performance is acceptable even in this worst-case situation (frequency offset equal to 5% the bit-rate).

    -0.5 -0.25 0 0.25 0.5-1.5

    -1

    -0.5

    0

    0.5

    1

    1.5

    Am

    plitu

    de

    Raw data (eye pattern)

    -0.5 -0.25 0 0.25 0.5-2

    0

    2

    4

    6Recovered data clock (eye pattern)

    Am

    plitu

    de

    Relative time, t/Tb Fig.2.5.6 – Bit synchronizer performance using 8 samples/bit and a master clock

    with frequency offset equal to 5% the bit-rate: Rb = 1 Mbit/s, fclk = 8.05 MHz.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    32

    2.5.4 Conclusions and further work

    The development of a new bit synchronizer for the CORTIVIS secondary system RF link has

    been described. The circuit is very simple and is ready to be incorporated in the final receiver.

    Performance tests have been conducted and the results show that all requirements are largely fulfilled

    and that no further adjustments are necessary.

    2.6 Power Delivery

    Some real experiments were conducted to determine the amount of power which could be

    magnetically induced from the primary to the secondary system and the corresponding power

    efficiency. Using the resonant transformer design and the transmitter described in Section 1, it was

    determined that it is possible to obtain about 200m W of power in the secondary system with an

    efficiency of about 50%. These results are presented in Section 1.4. Even considering some additional

    power loss in the DC source converters, this seems to be enough for an integrated low-power system

    design.

    3 Backward link design

    The feasibility of a backward (secondary-to-primary) data channel has been investigated. This channel

    is required for electrode and system maintenance. The solution offering the best

    performance/complexity ratio seems to be the use of a FDM (Frequency Division Multiplexing)

    scheme with a constant envelope modulation. It is worth pointing out that even if operation in the

    forward channel is in half-duplex mode (in terms of transmission of useful information), a FDM

    scheme is necessary because the primary system must continuously transmit a carrier signal to provide

    for the secondary system power and clock. Furthermore, the simpler transmitter will result if BPSK

    modulation is selected. At this point, the design of this backward link is being evaluated at the

    simulation macro level and no final results are yet available. Preliminary results however show that it

    is feasible although requiring a relatively complex receiver. This in turn does not pose an

  • CORTIVIS

    33

    unsurpassable obstacle since the receiver is located in the primary system where enough signal

    processing resources and power are available.

    4 Conclusions

    The work so far realized has been of significant importance in terms of deciding the modulation type

    to use in both links. We are now strongly inclined to use FSK in the forward link and BPSK in the

    backward link.

    The following points summarize the work that needs to be done in the next phase of this project:

    • Develop the required DC-DC converters for the secondary system power supply.

    • Specify and Develop the data processing digital block of Fig.1 which is responsible for frame

    disassembling and subsequent forwarding of the data bits to the electrode stimulator.

    • Determine a suitable carrier frequency to be employed in the backward link and develop the

    BPSK transmitter.

    • Develop the backward channel BPSK receiver. This receiver is expected to be a lot more

    complex than for example the FSK receiver in the secondary system.

    • Continue the study leading to the fabrication of the whole system in VLSI integrated circuits.

  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    34

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    35

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  • Evaluation of Different Wireless Communication Systems for Intracortical Prosthesis

    36

    Annex 1

    dcd

    bddnL 25.2.

    10075.43

    22 −+

    =

    Rayner formula for the inductance (µH) of a n turns multilayer cylindrical coil

    (dimensions in cm).

    ( )

    +−=

    −−

    −−=

    −=

    −=

    ×=

    −=

    +=+=+=−=

    ++=

    4

    4

    2

    24

    5

    2

    22

    92

    22

    21

    91

    125

    2

    22

    352

    25

    1

    13

    11

    1

    2

    221

    2222

    221121

    553311

    2221

    4105.20103.0

    ;43435.30

    43064.0 ;5.19

    24.0 ;5.12

    ; ; ; ;2.2

    004.0

    al

    allak

    Ax

    rx

    ax

    rxAK

    allak

    rx

    rxK

    lkrx

    rx

    AK

    AxrAxrxDxxDx

    KkKkKklxAannLM

    Mutual inductance (µH) between 2 single-layer coils (dimensions in cm).