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Essential Cell Biology provides an accessible introduction to the fundamental concepts of cellbiology. Its lively writing and exceptional illustrations make it the ideal textbook for a first course incell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging forthe introductory student. Molecular detail has been kept to a minimum inorder to provide the reader with a cohesive, conceptual framework of thebasic science that underlies our current understanding of biology.

The Third Edition is thoroughly updated scientifically, yet maintains theacademic level and size of the previous edition. The book is accompanied by a Media DVD-ROM with over 130 animations and videos, all the figuresfrom the book, and a new self-test quizzing feature for students.

NEW IN THE THIRD EDITIONu Completely updated throughout.u Based on student and instructor feedback, the Third Edition now includes:

• Integration of cell cycle and cell division into a single chapter.• Improved treatment of thermodynamics and energetics.• Integration of multi-media throughout text.• The addition of a quizzing feature to the Media Player.

u Greater focus on regulation, including new material on chromosome structure and epigenetics,post-transcriptional control (riboswitches, microRNAs, and RNAi), and metabolic controls.

u Additional attention to disease and medicine, including new material on quality control in protein production, cell-cell recognition, genetic variation, cancer treatments, and enhanced coverage of stem cells and their potential to treat disease.

u New treatment of genome evolution and comparative genomics.u New coverage of modern recombinant DNA and cell visualization technologies.u New “How We Know” sections.u Revised Question Bank for instructors including questions that can be

used with student response systems (i.e. clickers).

April 2009 • 860 pages • 850 illustrations Paperback • 978-0-8153-4130-7 • £45.00 Hardback • 978-0-8153-4129-1 • £94.00

CONTENTS1. Introduction to Cells2. Chemical Components of Cells3. Energy, Catalysis, and Biosynthesis4. Protein Structure and Function5. DNA and Chromosomes6. DNA Replication, Repair, and

Recombination7. From DNA to Protein: How Cells

Read the Genome8. Control of Gene Expression9. How Genes and Genomes Evolve10. Manipulating Genes and Cells

11. Membrane Structure12. Membrane Transport13. How Cells Obtain Energy from Food14. Energy Generation in Mitochondria

and Chloroplasts15. Intracellular Compartments and Transport16. Cell Communication17. Cytoskeleton18. The Cell Division Cycle19. Genetics, Meiosis, and the Molecular

Basis of Heredity20. Tissues and Cancer

To download a detailed table of contents and sample chapters, please visit:http://www.garlandscience.com/gs_textbooks.asp

HALLMARK FEATURESu The authors are known worldwide for their research, teaching, writing, and

leadership in science and science education.u The text reflects the accuracy, authority, and currency of the renowned

Molecular Biology of the Cell, but it is written at an introductory level.u Concept headings descriptively introduce each section.u The art program emphasizes central concepts without unnecessary detail.u “How We Know” sections in every chapter introduce experimental science by

explaining both the methods and scientific intuition of classical and currentexperiments.

u Questions interspersed throughout and at the end of each chapter test students’understanding and stimulate curiosity (all questions answered in the back of the book).

u Panels that concisely review basic science, principles, pathways, as well as other topics.

u Key terms in text listed at the end of each chapter.

u Detailed, illustrated glossary.u “Essential Concepts” review

for each chapter.

THE AUTHORSBruce Alberts received his Ph.D. from Harvard University and is Professor of Biochemistry and Biophysics at the University of California, San Francisco. He is the editor-in-chief of Science magazine. For 12 years he served as President of the U.S. National Academy of Sciences (1993-2005).

Dennis Bray received his Ph.D. from Massachusetts Institute of Technology and is currently an active emeritus professor at University of Cambridge. In 2006 he was awarded the Microsoft European Science Award.

Karen Hopkin received her Ph.D. in biochemistry from the Albert Einstein College of Medicine and is a science writer in Somerville, Massachusetts.

Alexander Johnson received his Ph.D. from Harvard University and is Professor of Microbiology and Immunology and Director of the Biochemistry, Cell Biology, Genetics, and Developmental Biology Graduate Program at the University of California, San Francisco.

Julian Lewis received his D.Phil. from the University of Oxford and is a Principal Scientist at the London Research Institute of Cancer Research UK.

Martin Raff received his M.D. from McGill University and is at the Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit and in the Biology Department at University College London.

Keith Roberts received his Ph.D. from the University of Cambridge and is Emeritus Fellow at the John Innes Centre, Norwich.

Peter Walter received his Ph.D. from The Rockefeller University in New York and is Professor and Chairman of the Department of Biochemistry and Biophysicsat the University of California, San Francisco, and an Investigator of the Howard Hughes Medical Institute.

MEDIA DVD-ROMThe Media DVD-ROM is packaged withevery copy of the book. It includes:

Essential Cell Biology InteractiveThe Essential Cell Biology Interactive MediaPlayer contains over 130 animations,videos, and molecular models. It alsoincludes a cell explorer program thatencourages students to investigate a set ofhigh-resolution micrographs.

Student Self-QuizzesThe quizzing feature, which is new to thisedition, allows students to test themselvesin basic reading comprehension of eachchapter. It is accessed through the EssentialCell Biology Interactive Media Player.

Movie VaultThe Movie Vault is an archive of moviesfrom the media player in three handyformats: QuickTime®, MPEG, and iPod®.

PowerPoint PresentationsThe figures from the book have been pre-loaded into PowerPoint presentations.There is one presentation for each chapter,and the files are located in a folder on theDVD-ROM. The files are also available onClasswire.

JPEG ArchiveThe individual figures from the book areavailable in JPEG format. They areorganized by chapter in folders on the DVD-ROM. They are also available on Classwire.

TEACHING SUPPLEMENTSThe Art of Essential Cell Biology, Third EditionThe images from the book are available in two convenient formats:PowerPoint® and JPEG. They are located in folders on the Media DVD-ROM or can be downloaded on the Web from Classwire™. On Classwire theindividual JPEGs are searchable by figure number, figure name, or bykeywords used in the figure legend from the book.

Figure Integrated Lecture OutlinesThe section headings, concept headings, and figures from the text have beenintegrated into PowerPoint presentations. These will be useful for instructorswho would like a head start creating lectures for their course. Like all of ourPowerPoint presentations, the lecture outlines can be customized. Forexample, the content of these presentations can be combined with videosfrom the DVD-ROM and questions from the book or “Question Bank,” in order to create unique lectures that facilitate interactive learning in theclassroom.

Question BankThe instructor Question Bank has been expanded with new questions. Each chapter will contain between 50-60 questions, and approximately 20-25of those will be new. Special effort has been made to create more multiple-choice questions that can be used with student response systems (i.e.clickers). In addition to the multiple-choice questions, the Question Bankincludes: fill-in-the-blank questions, matching questions, true/false questions,and concept questions or “thought questions,” which are particularlychallenging. The Question Bank is available on Classwire.

Media DVD-ROMThe Media DVD-ROM comes with every copy of the book and includes theEssential Cell Biology Interactive media player. Details about the DVD-ROMare located in the column to the right.

Garland Science Classwire™

All of the instructor supplements are available to qualified instructors onlineat the Garland Science Classwire Website. Garland Science Classwire offersaccess to other instructional resources from all of the Garland Sciencetextbooks, and provides free online course management tools. For additionalinformation, please visit http://www.classwire.com/garlandscience or e-mail science@garland.com.(Classwire™ is a trademark of Chalkfree, Inc.)

MOLECULAR BIOLOGY OF THE CELLFIFTH EDITIONBruce Alberts, Alexander Johnson, Julian Lewis,Martin Raff, Keith Roberts, and Peter WalterJanuary 2008 • 1,392 pages • 1,526 illustrationsHardback • 978-0-8153-4105-5 • £110.00Paperback • 978-0-8153-4106-2 • £59.99Packaged with a Media DVD-ROM

For nearly a quarter century Molecular Biology of the Cell has beenthe leading in-depth text reference in cell biology. This traditioncontinues with the new Fifth Edition, which has been completelyrevised and updated to describe our current, rapidly advancingunderstanding of cell biology. To list but a few examples, a largeamount of new material is presented on epigenetics; stem cells;RNAi; comparative genomics; the latest cancer therapies;apoptosis (now its own separate chapter); and cell cycle controland the mechanics of M phase (now integrated into one chapter).

The hallmark features of Molecular Biology of the Cell have beenretained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries.

THE PROBLEMS BOOKJohn Wilson and Tim HuntJanuary 2008 • 608 pages • 826 illustrationsPaperback • 978-0-8153-4110-9 • £25.00Packaged with a CD-ROM (contains solutions to all problems, and figures from the book)

The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understandingof how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter will review key terms,test for understanding basic concepts, and pose research-based problems. The Problems Book has been designed to correspondwith the first twenty chapters of Molecular Biology of the Cell, Fifth Edition.

• Includes the solutions to the end-of-chapter problems in the textbook Molecular Biology of the Cell, Fifth Edition.• Contains over 2,000 problems and their solutions.• All of the solutions to the problems in The Problems Book are on the CD-ROM that is packaged with every copy of the book.• The problems are organized into the following categories: Terms to Learn, Definitions, True/False, Thought Problems,

Calculations, and Data Handling.

The Problems Book will be useful for homework assignments and as a basis for class discussion. It could even provide inspirationfor exam questions.

CELLULAR SIGNAL PROCESSINGAN INTRODUCTION TO THE MOLECULAR MECHANISMS OF SIGNAL TRANSDUCTIONFriedrich Marks, Ursula Klingmüller and Karin Müller-DeckerDecember 2008 • 656 pages • 428 illustrationsPaperback • 978-0-8153-4215-1 • £42.50

Cellular Signal Processing is intended for use in signal transduction courses for undergraduateand graduate students. It offers a unifying view of cell signaling that is based on the concept ofprotein interactions acting as sophisticated data processing networks that govern intracellularand extracellular communication. The content is guided by three central principles: the proteinnetwork, its energy supply, and its evolution. Includes coverage of prokaryotic signaltransduction through to neuronal signaling and highlights the clinical aspects of cell signalingin health and disease.

• Chapter 3 discusses the evolution of cellular signal processing by focusing on prokaryoticsignal transduction, which links the major switching reactions of mammalian signalling toprokaryotic predecessors.

• Chapter 17 places signal transduction in context with systems biology and describes theformation and function of networks.

• Sidebars highlight complementary perspectives to the main discussion and strengthen thestudent’s understanding of essential concepts.

• Section summaries clarify the important points within each chapter.