e~ss - ivb.ro preoteasa vasile.pdf5. "fluorescence lifetime, precision calorimetry and...

5
r-- Europass Personal information First name(s) / Sumame(s) Curriculum Vitae Vasile Preoteasa Address(es) Telephone(s) 23 Constantin Kiritescu St., Sector 2, Bucharest, 024037, Romania +40213216470 I Mobile: I +40744903404 E-mail Fax(es) +40213192734 Date of birth 23.02.1954 Gender male [email protected] Nationality Romanian Desired employment I Occupational field Work experience Occupation or position held Dates April 1980 onwards Main activities and responsibilities Manager of research projects, responsibilities in quality management in research Researcher, Head of Nuclear Unit (1995 onwards) Areas of research: genotoxicity, radio labeling of biomolecules, mass spectrometry National Institute of Pathology "Victor Babes", 99-101 Splai Independentei, 050096, Bucharest, Type of business or sector Name and address of employer Romania Medical research Dates August 1979 - April 1980 Occupation or position held Biophysicist Main activities and responsibilities Controlling different pharmaceutical drugs through chemical and physical means Name and address of employer Bucharest Pharmaceutical Drug Factory, Romania Type of business or sector Technical quality assurance Education and training covered Name and type of organisation providing education and training Level in national or international classification Dates Title of qualification awarded Dates Title of qualification awarded Master degree Principal subjects/occupational skills Title: "The calorimetric and spectrofluorimetric study of normal chromatin and chromatin of cells treated with thioacetamine" Bucharest University, Biophysical Department, Romania ISCED5 1974 -1978 Bachelor degree 1978-1979 Page 1/5 - Curriculum vitae of I For more information on Europass go to http://europass. cedefop.europa.eu Preoleasa Vasile © European Union , 2004-2010 24082010

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Page 1: e~ss - ivb.ro Preoteasa Vasile.pdf5. "Fluorescence lifetime, precision calorimetry and fluorescence energy transfer measurements in the study of normal and tumoral chromatin structure"

e~ss r--

Europass

Personal information First name(s) Sumame(s)

Curriculum Vitae

Vasile Preoteasa Address(es)

Telephone(s)

23 Constantin Kiritescu St Sector 2 Bucharest 024037 Romania

+40213216470 I Mobile I +40744903404

E-mail

Fax(es) +40213192734

Date of birth 23021954

Gender male

unuclearvbabesro

Nationality Romanian

Desired employment I Occupational field

Work experience

Occupation or position held

Dates April 1980 onwards

Main activities and responsibilities Manager of research projects responsibilities in quality management in research

Researcher Head of Nuclear Unit (1995 onwards)

Areas of research genotoxicity radio labeling of biomolecules mass spectrometry

National Institute of Pathology Victor Babes 99-101 Splai Independentei 050096 Bucharest

Type of business or sector

Name and address of employer Romania

Medical research

Dates August 1979 shy April 1980

Occupation or position held Biophysicist

Main activities and responsibilities Controlling different pharmaceutical drugs through chemical and physical means

Name and address of employer Bucharest Pharmaceutical Drug Factory Romania

Type of business or sector Technical quality assurance

Education and training

covered

Name and type of organisation providing education and training

Level in national or international classification

Dates

Title of qualification awarded

Dates

Title of qualification awarded Master degree

Principal subjectsoccupational skills Title The calorimetric and spectrofluorimetric study of normal chromatin and chromatin of cells treated with thioacetamine

Bucharest University Biophysical Department Romania

ISCED5

1974 -1978

Bachelor degree

1978-1979

Page 15 - Curriculum vitae of I For more information on Europass go to httpeuropasscedefopeuropaeu Preoleasa Vasile copyEuropean Union 2004-2010 24082010

Principal subjectsloccupational skills Biophysics nuclear physics plasma shy spectrometry theoretical physics covered Title The spectrofluorimetric study of nUcleohistones shy dyes complexes

Name and type of organisation Bucharest University Biophysical Department Romania providing education and training

Level in national or international ISCED 5 classification

Personal skills and competences

Mother tongue(s) Romanian

Other language(s)

Self-assessment Understanding Speaking Writing

European level () Listening Reading Spoken interaction Spoken production

French 82 C1 82 81 C1

English 81 82 A2 A2 A2

() Common EUfOQean Framework o( Reierence (or Languages

Social skills and competences Good team player analytical mind

Organizational skills and Since 1995 I have managed and coordinated the nuclear unit team competences In 20061 have started a mass spectrometry team

I am part of the quality assurance team (ISO 9001)

Technical skills and competences Training courses

1987-Post university training course shy using radioactive isotopes shy University of Bucharest 2003-Training course for auditors in quality management in health system shy RENAR Centre 2005- Training course for auditors in environment management 2006- Training course in mass spectrometry ICP-MS - Agilrom Scientific Bucharest 2007- Training course in the REACH Directive of the European Council Parliament shy National Agency for Dangerous Substances and Chemicals Bucharest 2009-Postuniversity training course Radiological security shy National Institute for Physics Bucharest

Professional societies membership - Member of the Romanian radioprotection society - Member of the Romanian pure and applied biophysics society

Computer skills and competences Microsoft Office Windows 9x I XP

Artistic skills and competences Music (violin)

Other skills and competences Sports (volleyball) traveling

Driving license Bcategory

Annexes

Page 215 - Curriculum vitae of I For more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copyEuropean Union 2004-2010 24082010

I List of publications

1 Laser Action on Deoxyribonucleic Acid Radu Liliana Stirbet M Preoteasa V Laser Bologna 92 Monduzzi Editore 320 shy

3231992 2 The action of anticancer drugs thiotepa and lomustine and of E and A vitamins on tumor chromatin analyzed by thermal transition fluorescence methods and 1H NMR spectroscopy Radu Liliana Preoteasa V Lenghel Z Journal of Molecular Structure Elsevier Publishers Amsterdam 348 29 - 321995 3 Fluorescence spectroscopy in the study of fast neutrons irradiation effects on liver chromatin structure Radu Liliana Horer 0 Constantinescu B Preoteasa V Spectroscopy of Biological Molecules eds Merlin JC Turrell S Huvenne JP Kluwer Academic Publ 327-328 1995 4 Radiation protection of chromatin using vitamin 03 and estradion hormone Radu Liliana Preoteasa V Lenghel Z Constantinescu B Environmental Contamination 569-571 1996 5 Fluorescence lifetime precision calorimetry and fluorescence energy transfer measurements in the study of normal and tumoral chromatin structure Radu Liliana Preoteasa V Radulescu Irina Radu S Journal of Molecular Structure 408409 191-1951997 6 The role of Proteins and Metal ions in the Protection of Chromatin DNA at Fast Neutrons Action Radu Liliana Radulescu Irina Constantinescu B Preoteasa V Radioprotection 32 C1 112 1997 7 UV laser radiosensitivity of normal and tumoral chromatin Radu Liliana Mihailescu I Preoteasa V Radulescu I Gostian Doina Hening A Radu S Journal of the International Society for Optical Engineering 3405 2 678-685 1998 8 Fast neutrons action at chromatin level Radu Liliana Preoteasa V Radulescu Irina Gostian Doina Diagnosis and Treatment of Radiation Injury World Scientific Publishers in press 1998 9 A spectrophotometric spectrofluorimelric and calorimetric study of the modifications of chromatin structure by the carcinogen thioacetamide Radu Liliana Moraru I Gheorghe V Stirbet Alexandrina Preoteasa V Revue Roumaine de Biochimie 22 2 129-137 1985 10 A fluorescence energy transfer meth0d for the study of protein- nucleic acid interaction modification produced by the carcinogen thioacetamide in chromatin Radu Liliana Preoteasa V Horer 0 Revue Roumaine de Biochimie 22 3 233-239 1985 11 The effect of laser radiation on DNA from tumor cells Radu Liliana Stirbet M Preoteasa V Horer 0 Gostian Doina Ganciu G Studies and Researches in Physics 10553-5571991 12 The combined action of thiotepa and lomustine cytostatics of estradiol hormone and of E and A vitamins on Walker tumor chromatin structure Radu Liliana Preoteasa V Lenghel Z Rom Joumal Endocrinology 31 34 149 - 153 1993 13 Photolysis of chromatin by uv laser irradiation at 248 nm Radu Liliana Mihailescu lPreoteasa VConstantinescu B Romanian J Biophysics 5 4 383-389 1995 14 A possible correlation between unsch~duled DNA repair and cholesterolemia in Wistar rat modulated by vit E Daria Mihalache V Preoteasa Aura Carloban Alexandra Stanculescu CT Dragomir Romanian Archives of Microbiology and Immunology vol 60 nr 4 p 349 octombrie-decembrie 2001 15 Effects of combined Selenium and Vitamin E administration on DNA in Walker tumor bearing Wistar rat exposed to cytostatic acute treatment 2004 D MihalaGhe V Preoteasa V Barca Proceedings of the Free Papers of 2nd Intercontinental Congress of Pathology Iguassu Brasil 9-13 June 2004 16 Incidence of radiation-induced micronuclei in occupationally exposed subjects Daria Mihalache V Preoteasa Angela Petrescu - Romanian Journal of Biophysics vol 17 no 2 119-128 2007 17 The investigation of DNA structure rnodification produced by laser radiation Radu Liliana Preoteasa V Popescu Lucretia XVIII Annual Meeting of European Environmental Mutagen Society Drouzhba Varna 3-8 oct 1988 18 Chromatin structure in normal and tumor cells Radu Liliana Preoteasa V Horer 0 14-th International Congress of Biochemistry Praga 10-15 iulie 1988 Abstiact Book Fno 225 19 Action of laser radiation on tumor ccentlIs Radu Liliana Preoteasa V Gostian Doina Sixth European Conference on Clinical Oncology Florenta 27-31 oct 1991

20 The action of anticancer drugs thiotella and lomustine and of E and A vitamins on tumor chromatin analysed by thermal transition fluorescence methods isotope uptake and 1H NMR spectroscopy Radu Liliana Preoteasa V Lenghel Z EUCMOS XXII 22nd European Congress on Molecular Spectroscopy Abstracts Mo 13 119 Essen 11-16 septembrie 1994

Page 35 - Curriculum vitae of IFor more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copy European Union 2004-2010 24082010

21 The action of an ultraviolet excimer laser radiation on rat Walker tumour chromatin structure n Radu Liliana Preoteasa V Stirbet M Horer 0 XVI International Cancer Congress New Delhi 30 oct-5 nov 1994 22 Fluorescence spectroscopy in the study of fast neutrons irradiation effects on liver chromatin structure Radu Liliana Hbrer 0 Constantinescu B Preoteasa V 6-th Eur Conf on the Spectroscopy of Biological Molecules Lille 3-8 sept 1995 23 Radioprotection de la chromatine par 1$ vita mine D3 et Ihormone thyroxine Radu Liliana Constantinescu BPreoteasa V Hbrer 0 Gostian Doina Lenghel Z Jo~rnees dEtudes de Chimie sous Rayonnement Orleans-Nouan-Ie-Fuzelier Volum

des Resumes F-18 19-24 mai 1996 24 A fluorescence energy transfer method for the study of protein-nucleic acid interactions Radu Liliana Hbrer 0 Preoteasa V XXIII Europ Congo on Molecular Spectroscopy Balatonfured Proceedings nr PA 17 pag 12025-30 aug 1996 25 The role of proteins and metal ions in the protection of chromatin DNA at fast neutrons action Radu Liliana Radulescu Irina Serbanescu Ruxandra B Constantin~scu V Preoteasa 27 th Annual Meeting of the European Society for Radiation Biology Montpellier Proceedings 320 pagi 34 1-5 sept 1996 26 The protection by proteins of chromqtin DNA against UV laser radiation Radu Liliana Preoteasa V Mihailescu I Radulescu Irina 12 th International Congress on Photobiology Viena Abstracts P 25 251 1-6 sept 1996 27 The laser irradiated chromatin structure studied by fluorescence spectroscopy Radu Liliana Radulescu Irina Serbanescu Ruxandra Preoteasa V Mihilescu I Lenghel Z 11-th Balkan Biophysical and Biochemical Days Salonic Grecia 15-17 mai 1997 28 UV laser radiosensitivity of normal ard tumour cells chromatin Radu Liliana Preoteasa V Radulescu Irina 28-th Annual Meeting of the European Society for iRadiation Research Oxfor Anglia 24-27 sept 1997 29 Spectrofluorimetric analysis of fast n~utrons action on chromatin influence of cytostatic and scavengers molecules Radu Liliana Radulescu Irina GazdaruDoina Constantinescu B Preoteasa V XXIV European Congress on Molecular Spectroscopy Praga 23-28 august 1998 30 Normal and tumor cells chromatin str~cture analysed by fluorimetric methods Liliana Radu V Preoteasa O Horer Doina Gazdaru 16th Congress of the Europyan Association of Cancer Research Thessaloniki 30 May-30 June 2000 31 Effect of radioprotective agent on qhromatin radiolysis V Preoteasa Adriana Costache Daria Mihalache Irina Radulescu 12th Balkan Biochemical Biophysical Days Bucharest May 10-13 2001 abstract book pg 83 32 Correlation between serum cholesterol level and DNA biosynthesis in liver cells Daria Mihalache V Preoteasa Irina Radulescu CT Dragomir 12th Balkan Biochemical Biophysical Days Bucharest May 10-13 2001 abstract book pg 63 33 Role of chromatin structure in UV laser radiolysis Preoteasa V Radu Liliana Radulescu Irina Martin C IV-th National Conference of Biophysics Abtra P-11 Cluj-Napoca 16-18 oct 1997 34 Normal and tumor cells chromatin st~ucture analysed by fluorimetric methods Liliana Radu V Preoteasa O Horer Doina Gazdaru XVI-Congress of the European Association of Cancer Recherch Thessaloniki 30 may-3 june 2000 35 Effect of radioprotective agent on centhromatin radiolysis V Preoteasa Adriana Costache Daria Mihalache Irina Radulescu 12th Balkan Biochemical Bioph~sical Days Bucharest May 10-13 2001 Abs Book p 83 36 Dependance de Iaction des neutrons rppides de la structure de la chromatine L Radu V Preoteasa B Constantinescu D Gazdaru Cinquieme Colloque International de Radiobiologie Fondamentale et Applique 18-22 juin 2001 37 Serum cholesterol level influencing t~e unscheduled DNA repair synthesis in rat hepatocyte Daria Mihalache Aura Carloban Alexandra Stanculescu V Preoteasa XXIVth Intern Congress of the Intern Acad Of Pathology abstr 17651 oct 2002 38 Microdosimetrie des radio lesions de la chromatine produites par les neutrons rapides L Radu V Preoteasa D Gazdaru B Constantinescu 6eme Colloque International de Radiobiologie Fondamentale et Applique 30 juin - 4 juillet 2003 Batz sur Mer 39 Special assays for chromatin DNA raqiation damage L Radu V Preoteasa B Constantinescu O Horer D Gazdaru 8th International Workshop Radiation Damage to DNA may 25-30 Alberta Canada 2004 40 Selenium and Vitamin E modulatory ~ffects on genomic DNA Double-Strand Breaks induced by chemical carcinogens in acute treatment in Wistar rats V Barc Daria Mihalache V Preoteasa acceptat la XXV Congress of the International Accademy of Pathology Brisbane Australia 10-15 Oct 2004 41 Spectrofluorimetric aspects of chromain gammalysis Preoteasa Vasile Vasile Gabriel J Daria Mihalache Barca Valentin Gheorghe Balasa - 4Th National Symposium of Pathology 31 oct-2 nov 2004 Bucharest 42 Spectrophotometric analysis of chromtin gammalysis V Preoteasa V Gabriel Daria Mihalache V Barca Gh Balasa - 8-th Romanian Biophysics Conference A~vanced Biomaterials and Biophysical Techniques may 26-28 2005 lasy Romania

Page 45 - Curriculum vitae of I Fo~ more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copyEiuropean Union 2004-2010 24082010

43 Chemical Modulation of Chromatin Gammalysis V Preoteasa G Vasile D Mihalache V Barca G Balasa The 15thshyIUPAB5th EBSA International Biophysics Cqngress Montpeliier France 01 092005 44 Incidence of radiation-induced micronucentlei in occupationally exposed subjects Daria Mihalache V Preoteasa Angela Petrescu Romanian J Biophys 17 (2)200( 45 Oxitocin receptor expression dynamics in human myometrium during pregnancy V Barca D Matei A Spataru Gabriela Barca V Preoteasa Daria Mihalache 3Th National Symposium of Pathology 31 oct-2 nov 2006 Bucharest 46 Liquid scintillation comparative ass~sssment of 3H bioaccumulation in two Sedum and Sempervivum species (Crassulaceae) co-inhabiting a central Dobtogean site Niculae M Barca V Varga A Zavidei V Nedescu L Jeledintan EM Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 47 ICP-MS comparative elemental analysis and bioconcentration capacity of two Sedum and Sempervivum species (Crassulaceae) Barca V Niculae M Varga A Zavidei V Nedescu L Jeledintan EM Matei D Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 48 Precise method for detection of metal traces in biological tissue V Preoteasa D Arsene V Barca F Mitu Daria Mihalache 4Th National Symposium of Pat~ology 31 10-211 2007 Bucharest 49 The frequency and morphological chwacteristics of interstitial Cajal cell-like in human leiomyoma Daria Mihalache V Preoteasa E Mandache Mihaela Gherghiceanu Maria Sajin Alina Chefani Anca Lazaroiu Elena Tianu 4Th National Symposium of Pathology 31 10-2112007 Sucharest 50 Zinc and other metals as factors invqlved in beta-amyloid peptide deposition in human brain A real role or random association D Arsene V Preoteasa A Balan S Tuta D Terzea F Vasilescu M Ceausu V Muntean A Anghel C Ardeleanu C losif I Alexandrescu C Pop$ 4Th National Symposium of Pathology 31 oct-2 nov 2007 Bucharest 51 The effect in vitro of the metotrexat ahd leflunomid on the pathologic monocytes from patients with rheumatic arthritis Neagoe lonela Victoria Balanescu Andra ~odica Preoteasa V Butur Georgeta Carolina Negrei Manda Gina 6th National Symposium of Pathology 3 - 5 november ~009 52 New nucleoside analogues conformatiqnally restricted with antitumor activity in vitro Neagoe lonela Victoria Preoteasa V Tanase Cristiana Postolache C Matei L Baconi DL Manda Gina AI 6-lea Simpozion National de Patologie 3 - 5 noiembrie 2009 53 Microelements accumulation in transgenic mouse tissues Preoteasa V Mitu F Neagoe lonela Victoria Savi G Savi

I

Ileana Geogia Daniela Butnariu Luminita qth National Symposium of Pathology 3 - 5 november 2009 54 Pro-inflammatory Signal delivered in vi~ro by leflunomide active metabolite A77 1726 on abnormal peripheral monocytes in rheumatoid arthritis Popa L Negrei C Neagoe IV Albulescu L Preoteasa V Balanescu AR Ghica MV Manda G Farmacia 58(5) 546-558 2010 IF 0144 ISSN 0014-8237 55 Early immune changes induced by Icentflunomide therapy in rheumatoid arthritis Manda G Neagoe IV Preoteasa V Balanescu AR Int Immunol 22 (Suppl 1) IpP036-45 2010 (14S1 Intemational Congress of Immunology 22-27 august 2010 Kobe Japonia) IF 3403 ISSN 0953-8178 56 Cellular immunity in rheumatoid art1ritis patients not responding to synthetic DMARDs Balanescu A Neagoe IV Berghea F Negrei C Parvu M lonescu R Predeteanu D Bojinca V Preoteasa V Manda G Arthrit isamp Rheumatism 62 (10shySuppl) S353 pg 848 (ACRARHP 201 0 A~nual Scientific Meeting 6-11 noiembrie 2010 Atlanta SUA) IF 7332 ISSN 1529shy0131 57 Trace metals as factors involved in hurnan neurodegeneration real rol or random association D Arsene V Preoteasa A Petrescu A Balan and C Ardeleanu Trflce Elements and Electrolytes vol 28 No42011 (221-231)

0111 2011 CS III Vasile Preoteasa

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Page 55 - Curriculum vitae of I For (lore information on Europass go to httpeuropasscedefop europaeu Preoleasa Vasile copy E~ropean Union 2004-2010 2408201 0

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Page 2: e~ss - ivb.ro Preoteasa Vasile.pdf5. "Fluorescence lifetime, precision calorimetry and fluorescence energy transfer measurements in the study of normal and tumoral chromatin structure"

Principal subjectsloccupational skills Biophysics nuclear physics plasma shy spectrometry theoretical physics covered Title The spectrofluorimetric study of nUcleohistones shy dyes complexes

Name and type of organisation Bucharest University Biophysical Department Romania providing education and training

Level in national or international ISCED 5 classification

Personal skills and competences

Mother tongue(s) Romanian

Other language(s)

Self-assessment Understanding Speaking Writing

European level () Listening Reading Spoken interaction Spoken production

French 82 C1 82 81 C1

English 81 82 A2 A2 A2

() Common EUfOQean Framework o( Reierence (or Languages

Social skills and competences Good team player analytical mind

Organizational skills and Since 1995 I have managed and coordinated the nuclear unit team competences In 20061 have started a mass spectrometry team

I am part of the quality assurance team (ISO 9001)

Technical skills and competences Training courses

1987-Post university training course shy using radioactive isotopes shy University of Bucharest 2003-Training course for auditors in quality management in health system shy RENAR Centre 2005- Training course for auditors in environment management 2006- Training course in mass spectrometry ICP-MS - Agilrom Scientific Bucharest 2007- Training course in the REACH Directive of the European Council Parliament shy National Agency for Dangerous Substances and Chemicals Bucharest 2009-Postuniversity training course Radiological security shy National Institute for Physics Bucharest

Professional societies membership - Member of the Romanian radioprotection society - Member of the Romanian pure and applied biophysics society

Computer skills and competences Microsoft Office Windows 9x I XP

Artistic skills and competences Music (violin)

Other skills and competences Sports (volleyball) traveling

Driving license Bcategory

Annexes

Page 215 - Curriculum vitae of I For more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copyEuropean Union 2004-2010 24082010

I List of publications

1 Laser Action on Deoxyribonucleic Acid Radu Liliana Stirbet M Preoteasa V Laser Bologna 92 Monduzzi Editore 320 shy

3231992 2 The action of anticancer drugs thiotepa and lomustine and of E and A vitamins on tumor chromatin analyzed by thermal transition fluorescence methods and 1H NMR spectroscopy Radu Liliana Preoteasa V Lenghel Z Journal of Molecular Structure Elsevier Publishers Amsterdam 348 29 - 321995 3 Fluorescence spectroscopy in the study of fast neutrons irradiation effects on liver chromatin structure Radu Liliana Horer 0 Constantinescu B Preoteasa V Spectroscopy of Biological Molecules eds Merlin JC Turrell S Huvenne JP Kluwer Academic Publ 327-328 1995 4 Radiation protection of chromatin using vitamin 03 and estradion hormone Radu Liliana Preoteasa V Lenghel Z Constantinescu B Environmental Contamination 569-571 1996 5 Fluorescence lifetime precision calorimetry and fluorescence energy transfer measurements in the study of normal and tumoral chromatin structure Radu Liliana Preoteasa V Radulescu Irina Radu S Journal of Molecular Structure 408409 191-1951997 6 The role of Proteins and Metal ions in the Protection of Chromatin DNA at Fast Neutrons Action Radu Liliana Radulescu Irina Constantinescu B Preoteasa V Radioprotection 32 C1 112 1997 7 UV laser radiosensitivity of normal and tumoral chromatin Radu Liliana Mihailescu I Preoteasa V Radulescu I Gostian Doina Hening A Radu S Journal of the International Society for Optical Engineering 3405 2 678-685 1998 8 Fast neutrons action at chromatin level Radu Liliana Preoteasa V Radulescu Irina Gostian Doina Diagnosis and Treatment of Radiation Injury World Scientific Publishers in press 1998 9 A spectrophotometric spectrofluorimelric and calorimetric study of the modifications of chromatin structure by the carcinogen thioacetamide Radu Liliana Moraru I Gheorghe V Stirbet Alexandrina Preoteasa V Revue Roumaine de Biochimie 22 2 129-137 1985 10 A fluorescence energy transfer meth0d for the study of protein- nucleic acid interaction modification produced by the carcinogen thioacetamide in chromatin Radu Liliana Preoteasa V Horer 0 Revue Roumaine de Biochimie 22 3 233-239 1985 11 The effect of laser radiation on DNA from tumor cells Radu Liliana Stirbet M Preoteasa V Horer 0 Gostian Doina Ganciu G Studies and Researches in Physics 10553-5571991 12 The combined action of thiotepa and lomustine cytostatics of estradiol hormone and of E and A vitamins on Walker tumor chromatin structure Radu Liliana Preoteasa V Lenghel Z Rom Joumal Endocrinology 31 34 149 - 153 1993 13 Photolysis of chromatin by uv laser irradiation at 248 nm Radu Liliana Mihailescu lPreoteasa VConstantinescu B Romanian J Biophysics 5 4 383-389 1995 14 A possible correlation between unsch~duled DNA repair and cholesterolemia in Wistar rat modulated by vit E Daria Mihalache V Preoteasa Aura Carloban Alexandra Stanculescu CT Dragomir Romanian Archives of Microbiology and Immunology vol 60 nr 4 p 349 octombrie-decembrie 2001 15 Effects of combined Selenium and Vitamin E administration on DNA in Walker tumor bearing Wistar rat exposed to cytostatic acute treatment 2004 D MihalaGhe V Preoteasa V Barca Proceedings of the Free Papers of 2nd Intercontinental Congress of Pathology Iguassu Brasil 9-13 June 2004 16 Incidence of radiation-induced micronuclei in occupationally exposed subjects Daria Mihalache V Preoteasa Angela Petrescu - Romanian Journal of Biophysics vol 17 no 2 119-128 2007 17 The investigation of DNA structure rnodification produced by laser radiation Radu Liliana Preoteasa V Popescu Lucretia XVIII Annual Meeting of European Environmental Mutagen Society Drouzhba Varna 3-8 oct 1988 18 Chromatin structure in normal and tumor cells Radu Liliana Preoteasa V Horer 0 14-th International Congress of Biochemistry Praga 10-15 iulie 1988 Abstiact Book Fno 225 19 Action of laser radiation on tumor ccentlIs Radu Liliana Preoteasa V Gostian Doina Sixth European Conference on Clinical Oncology Florenta 27-31 oct 1991

20 The action of anticancer drugs thiotella and lomustine and of E and A vitamins on tumor chromatin analysed by thermal transition fluorescence methods isotope uptake and 1H NMR spectroscopy Radu Liliana Preoteasa V Lenghel Z EUCMOS XXII 22nd European Congress on Molecular Spectroscopy Abstracts Mo 13 119 Essen 11-16 septembrie 1994

Page 35 - Curriculum vitae of IFor more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copy European Union 2004-2010 24082010

21 The action of an ultraviolet excimer laser radiation on rat Walker tumour chromatin structure n Radu Liliana Preoteasa V Stirbet M Horer 0 XVI International Cancer Congress New Delhi 30 oct-5 nov 1994 22 Fluorescence spectroscopy in the study of fast neutrons irradiation effects on liver chromatin structure Radu Liliana Hbrer 0 Constantinescu B Preoteasa V 6-th Eur Conf on the Spectroscopy of Biological Molecules Lille 3-8 sept 1995 23 Radioprotection de la chromatine par 1$ vita mine D3 et Ihormone thyroxine Radu Liliana Constantinescu BPreoteasa V Hbrer 0 Gostian Doina Lenghel Z Jo~rnees dEtudes de Chimie sous Rayonnement Orleans-Nouan-Ie-Fuzelier Volum

des Resumes F-18 19-24 mai 1996 24 A fluorescence energy transfer method for the study of protein-nucleic acid interactions Radu Liliana Hbrer 0 Preoteasa V XXIII Europ Congo on Molecular Spectroscopy Balatonfured Proceedings nr PA 17 pag 12025-30 aug 1996 25 The role of proteins and metal ions in the protection of chromatin DNA at fast neutrons action Radu Liliana Radulescu Irina Serbanescu Ruxandra B Constantin~scu V Preoteasa 27 th Annual Meeting of the European Society for Radiation Biology Montpellier Proceedings 320 pagi 34 1-5 sept 1996 26 The protection by proteins of chromqtin DNA against UV laser radiation Radu Liliana Preoteasa V Mihailescu I Radulescu Irina 12 th International Congress on Photobiology Viena Abstracts P 25 251 1-6 sept 1996 27 The laser irradiated chromatin structure studied by fluorescence spectroscopy Radu Liliana Radulescu Irina Serbanescu Ruxandra Preoteasa V Mihilescu I Lenghel Z 11-th Balkan Biophysical and Biochemical Days Salonic Grecia 15-17 mai 1997 28 UV laser radiosensitivity of normal ard tumour cells chromatin Radu Liliana Preoteasa V Radulescu Irina 28-th Annual Meeting of the European Society for iRadiation Research Oxfor Anglia 24-27 sept 1997 29 Spectrofluorimetric analysis of fast n~utrons action on chromatin influence of cytostatic and scavengers molecules Radu Liliana Radulescu Irina GazdaruDoina Constantinescu B Preoteasa V XXIV European Congress on Molecular Spectroscopy Praga 23-28 august 1998 30 Normal and tumor cells chromatin str~cture analysed by fluorimetric methods Liliana Radu V Preoteasa O Horer Doina Gazdaru 16th Congress of the Europyan Association of Cancer Research Thessaloniki 30 May-30 June 2000 31 Effect of radioprotective agent on qhromatin radiolysis V Preoteasa Adriana Costache Daria Mihalache Irina Radulescu 12th Balkan Biochemical Biophysical Days Bucharest May 10-13 2001 abstract book pg 83 32 Correlation between serum cholesterol level and DNA biosynthesis in liver cells Daria Mihalache V Preoteasa Irina Radulescu CT Dragomir 12th Balkan Biochemical Biophysical Days Bucharest May 10-13 2001 abstract book pg 63 33 Role of chromatin structure in UV laser radiolysis Preoteasa V Radu Liliana Radulescu Irina Martin C IV-th National Conference of Biophysics Abtra P-11 Cluj-Napoca 16-18 oct 1997 34 Normal and tumor cells chromatin st~ucture analysed by fluorimetric methods Liliana Radu V Preoteasa O Horer Doina Gazdaru XVI-Congress of the European Association of Cancer Recherch Thessaloniki 30 may-3 june 2000 35 Effect of radioprotective agent on centhromatin radiolysis V Preoteasa Adriana Costache Daria Mihalache Irina Radulescu 12th Balkan Biochemical Bioph~sical Days Bucharest May 10-13 2001 Abs Book p 83 36 Dependance de Iaction des neutrons rppides de la structure de la chromatine L Radu V Preoteasa B Constantinescu D Gazdaru Cinquieme Colloque International de Radiobiologie Fondamentale et Applique 18-22 juin 2001 37 Serum cholesterol level influencing t~e unscheduled DNA repair synthesis in rat hepatocyte Daria Mihalache Aura Carloban Alexandra Stanculescu V Preoteasa XXIVth Intern Congress of the Intern Acad Of Pathology abstr 17651 oct 2002 38 Microdosimetrie des radio lesions de la chromatine produites par les neutrons rapides L Radu V Preoteasa D Gazdaru B Constantinescu 6eme Colloque International de Radiobiologie Fondamentale et Applique 30 juin - 4 juillet 2003 Batz sur Mer 39 Special assays for chromatin DNA raqiation damage L Radu V Preoteasa B Constantinescu O Horer D Gazdaru 8th International Workshop Radiation Damage to DNA may 25-30 Alberta Canada 2004 40 Selenium and Vitamin E modulatory ~ffects on genomic DNA Double-Strand Breaks induced by chemical carcinogens in acute treatment in Wistar rats V Barc Daria Mihalache V Preoteasa acceptat la XXV Congress of the International Accademy of Pathology Brisbane Australia 10-15 Oct 2004 41 Spectrofluorimetric aspects of chromain gammalysis Preoteasa Vasile Vasile Gabriel J Daria Mihalache Barca Valentin Gheorghe Balasa - 4Th National Symposium of Pathology 31 oct-2 nov 2004 Bucharest 42 Spectrophotometric analysis of chromtin gammalysis V Preoteasa V Gabriel Daria Mihalache V Barca Gh Balasa - 8-th Romanian Biophysics Conference A~vanced Biomaterials and Biophysical Techniques may 26-28 2005 lasy Romania

Page 45 - Curriculum vitae of I Fo~ more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copyEiuropean Union 2004-2010 24082010

43 Chemical Modulation of Chromatin Gammalysis V Preoteasa G Vasile D Mihalache V Barca G Balasa The 15thshyIUPAB5th EBSA International Biophysics Cqngress Montpeliier France 01 092005 44 Incidence of radiation-induced micronucentlei in occupationally exposed subjects Daria Mihalache V Preoteasa Angela Petrescu Romanian J Biophys 17 (2)200( 45 Oxitocin receptor expression dynamics in human myometrium during pregnancy V Barca D Matei A Spataru Gabriela Barca V Preoteasa Daria Mihalache 3Th National Symposium of Pathology 31 oct-2 nov 2006 Bucharest 46 Liquid scintillation comparative ass~sssment of 3H bioaccumulation in two Sedum and Sempervivum species (Crassulaceae) co-inhabiting a central Dobtogean site Niculae M Barca V Varga A Zavidei V Nedescu L Jeledintan EM Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 47 ICP-MS comparative elemental analysis and bioconcentration capacity of two Sedum and Sempervivum species (Crassulaceae) Barca V Niculae M Varga A Zavidei V Nedescu L Jeledintan EM Matei D Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 48 Precise method for detection of metal traces in biological tissue V Preoteasa D Arsene V Barca F Mitu Daria Mihalache 4Th National Symposium of Pat~ology 31 10-211 2007 Bucharest 49 The frequency and morphological chwacteristics of interstitial Cajal cell-like in human leiomyoma Daria Mihalache V Preoteasa E Mandache Mihaela Gherghiceanu Maria Sajin Alina Chefani Anca Lazaroiu Elena Tianu 4Th National Symposium of Pathology 31 10-2112007 Sucharest 50 Zinc and other metals as factors invqlved in beta-amyloid peptide deposition in human brain A real role or random association D Arsene V Preoteasa A Balan S Tuta D Terzea F Vasilescu M Ceausu V Muntean A Anghel C Ardeleanu C losif I Alexandrescu C Pop$ 4Th National Symposium of Pathology 31 oct-2 nov 2007 Bucharest 51 The effect in vitro of the metotrexat ahd leflunomid on the pathologic monocytes from patients with rheumatic arthritis Neagoe lonela Victoria Balanescu Andra ~odica Preoteasa V Butur Georgeta Carolina Negrei Manda Gina 6th National Symposium of Pathology 3 - 5 november ~009 52 New nucleoside analogues conformatiqnally restricted with antitumor activity in vitro Neagoe lonela Victoria Preoteasa V Tanase Cristiana Postolache C Matei L Baconi DL Manda Gina AI 6-lea Simpozion National de Patologie 3 - 5 noiembrie 2009 53 Microelements accumulation in transgenic mouse tissues Preoteasa V Mitu F Neagoe lonela Victoria Savi G Savi

I

Ileana Geogia Daniela Butnariu Luminita qth National Symposium of Pathology 3 - 5 november 2009 54 Pro-inflammatory Signal delivered in vi~ro by leflunomide active metabolite A77 1726 on abnormal peripheral monocytes in rheumatoid arthritis Popa L Negrei C Neagoe IV Albulescu L Preoteasa V Balanescu AR Ghica MV Manda G Farmacia 58(5) 546-558 2010 IF 0144 ISSN 0014-8237 55 Early immune changes induced by Icentflunomide therapy in rheumatoid arthritis Manda G Neagoe IV Preoteasa V Balanescu AR Int Immunol 22 (Suppl 1) IpP036-45 2010 (14S1 Intemational Congress of Immunology 22-27 august 2010 Kobe Japonia) IF 3403 ISSN 0953-8178 56 Cellular immunity in rheumatoid art1ritis patients not responding to synthetic DMARDs Balanescu A Neagoe IV Berghea F Negrei C Parvu M lonescu R Predeteanu D Bojinca V Preoteasa V Manda G Arthrit isamp Rheumatism 62 (10shySuppl) S353 pg 848 (ACRARHP 201 0 A~nual Scientific Meeting 6-11 noiembrie 2010 Atlanta SUA) IF 7332 ISSN 1529shy0131 57 Trace metals as factors involved in hurnan neurodegeneration real rol or random association D Arsene V Preoteasa A Petrescu A Balan and C Ardeleanu Trflce Elements and Electrolytes vol 28 No42011 (221-231)

0111 2011 CS III Vasile Preoteasa

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Page 55 - Curriculum vitae of I For (lore information on Europass go to httpeuropasscedefop europaeu Preoleasa Vasile copy E~ropean Union 2004-2010 2408201 0

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Page 3: e~ss - ivb.ro Preoteasa Vasile.pdf5. "Fluorescence lifetime, precision calorimetry and fluorescence energy transfer measurements in the study of normal and tumoral chromatin structure"

I List of publications

1 Laser Action on Deoxyribonucleic Acid Radu Liliana Stirbet M Preoteasa V Laser Bologna 92 Monduzzi Editore 320 shy

3231992 2 The action of anticancer drugs thiotepa and lomustine and of E and A vitamins on tumor chromatin analyzed by thermal transition fluorescence methods and 1H NMR spectroscopy Radu Liliana Preoteasa V Lenghel Z Journal of Molecular Structure Elsevier Publishers Amsterdam 348 29 - 321995 3 Fluorescence spectroscopy in the study of fast neutrons irradiation effects on liver chromatin structure Radu Liliana Horer 0 Constantinescu B Preoteasa V Spectroscopy of Biological Molecules eds Merlin JC Turrell S Huvenne JP Kluwer Academic Publ 327-328 1995 4 Radiation protection of chromatin using vitamin 03 and estradion hormone Radu Liliana Preoteasa V Lenghel Z Constantinescu B Environmental Contamination 569-571 1996 5 Fluorescence lifetime precision calorimetry and fluorescence energy transfer measurements in the study of normal and tumoral chromatin structure Radu Liliana Preoteasa V Radulescu Irina Radu S Journal of Molecular Structure 408409 191-1951997 6 The role of Proteins and Metal ions in the Protection of Chromatin DNA at Fast Neutrons Action Radu Liliana Radulescu Irina Constantinescu B Preoteasa V Radioprotection 32 C1 112 1997 7 UV laser radiosensitivity of normal and tumoral chromatin Radu Liliana Mihailescu I Preoteasa V Radulescu I Gostian Doina Hening A Radu S Journal of the International Society for Optical Engineering 3405 2 678-685 1998 8 Fast neutrons action at chromatin level Radu Liliana Preoteasa V Radulescu Irina Gostian Doina Diagnosis and Treatment of Radiation Injury World Scientific Publishers in press 1998 9 A spectrophotometric spectrofluorimelric and calorimetric study of the modifications of chromatin structure by the carcinogen thioacetamide Radu Liliana Moraru I Gheorghe V Stirbet Alexandrina Preoteasa V Revue Roumaine de Biochimie 22 2 129-137 1985 10 A fluorescence energy transfer meth0d for the study of protein- nucleic acid interaction modification produced by the carcinogen thioacetamide in chromatin Radu Liliana Preoteasa V Horer 0 Revue Roumaine de Biochimie 22 3 233-239 1985 11 The effect of laser radiation on DNA from tumor cells Radu Liliana Stirbet M Preoteasa V Horer 0 Gostian Doina Ganciu G Studies and Researches in Physics 10553-5571991 12 The combined action of thiotepa and lomustine cytostatics of estradiol hormone and of E and A vitamins on Walker tumor chromatin structure Radu Liliana Preoteasa V Lenghel Z Rom Joumal Endocrinology 31 34 149 - 153 1993 13 Photolysis of chromatin by uv laser irradiation at 248 nm Radu Liliana Mihailescu lPreoteasa VConstantinescu B Romanian J Biophysics 5 4 383-389 1995 14 A possible correlation between unsch~duled DNA repair and cholesterolemia in Wistar rat modulated by vit E Daria Mihalache V Preoteasa Aura Carloban Alexandra Stanculescu CT Dragomir Romanian Archives of Microbiology and Immunology vol 60 nr 4 p 349 octombrie-decembrie 2001 15 Effects of combined Selenium and Vitamin E administration on DNA in Walker tumor bearing Wistar rat exposed to cytostatic acute treatment 2004 D MihalaGhe V Preoteasa V Barca Proceedings of the Free Papers of 2nd Intercontinental Congress of Pathology Iguassu Brasil 9-13 June 2004 16 Incidence of radiation-induced micronuclei in occupationally exposed subjects Daria Mihalache V Preoteasa Angela Petrescu - Romanian Journal of Biophysics vol 17 no 2 119-128 2007 17 The investigation of DNA structure rnodification produced by laser radiation Radu Liliana Preoteasa V Popescu Lucretia XVIII Annual Meeting of European Environmental Mutagen Society Drouzhba Varna 3-8 oct 1988 18 Chromatin structure in normal and tumor cells Radu Liliana Preoteasa V Horer 0 14-th International Congress of Biochemistry Praga 10-15 iulie 1988 Abstiact Book Fno 225 19 Action of laser radiation on tumor ccentlIs Radu Liliana Preoteasa V Gostian Doina Sixth European Conference on Clinical Oncology Florenta 27-31 oct 1991

20 The action of anticancer drugs thiotella and lomustine and of E and A vitamins on tumor chromatin analysed by thermal transition fluorescence methods isotope uptake and 1H NMR spectroscopy Radu Liliana Preoteasa V Lenghel Z EUCMOS XXII 22nd European Congress on Molecular Spectroscopy Abstracts Mo 13 119 Essen 11-16 septembrie 1994

Page 35 - Curriculum vitae of IFor more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copy European Union 2004-2010 24082010

21 The action of an ultraviolet excimer laser radiation on rat Walker tumour chromatin structure n Radu Liliana Preoteasa V Stirbet M Horer 0 XVI International Cancer Congress New Delhi 30 oct-5 nov 1994 22 Fluorescence spectroscopy in the study of fast neutrons irradiation effects on liver chromatin structure Radu Liliana Hbrer 0 Constantinescu B Preoteasa V 6-th Eur Conf on the Spectroscopy of Biological Molecules Lille 3-8 sept 1995 23 Radioprotection de la chromatine par 1$ vita mine D3 et Ihormone thyroxine Radu Liliana Constantinescu BPreoteasa V Hbrer 0 Gostian Doina Lenghel Z Jo~rnees dEtudes de Chimie sous Rayonnement Orleans-Nouan-Ie-Fuzelier Volum

des Resumes F-18 19-24 mai 1996 24 A fluorescence energy transfer method for the study of protein-nucleic acid interactions Radu Liliana Hbrer 0 Preoteasa V XXIII Europ Congo on Molecular Spectroscopy Balatonfured Proceedings nr PA 17 pag 12025-30 aug 1996 25 The role of proteins and metal ions in the protection of chromatin DNA at fast neutrons action Radu Liliana Radulescu Irina Serbanescu Ruxandra B Constantin~scu V Preoteasa 27 th Annual Meeting of the European Society for Radiation Biology Montpellier Proceedings 320 pagi 34 1-5 sept 1996 26 The protection by proteins of chromqtin DNA against UV laser radiation Radu Liliana Preoteasa V Mihailescu I Radulescu Irina 12 th International Congress on Photobiology Viena Abstracts P 25 251 1-6 sept 1996 27 The laser irradiated chromatin structure studied by fluorescence spectroscopy Radu Liliana Radulescu Irina Serbanescu Ruxandra Preoteasa V Mihilescu I Lenghel Z 11-th Balkan Biophysical and Biochemical Days Salonic Grecia 15-17 mai 1997 28 UV laser radiosensitivity of normal ard tumour cells chromatin Radu Liliana Preoteasa V Radulescu Irina 28-th Annual Meeting of the European Society for iRadiation Research Oxfor Anglia 24-27 sept 1997 29 Spectrofluorimetric analysis of fast n~utrons action on chromatin influence of cytostatic and scavengers molecules Radu Liliana Radulescu Irina GazdaruDoina Constantinescu B Preoteasa V XXIV European Congress on Molecular Spectroscopy Praga 23-28 august 1998 30 Normal and tumor cells chromatin str~cture analysed by fluorimetric methods Liliana Radu V Preoteasa O Horer Doina Gazdaru 16th Congress of the Europyan Association of Cancer Research Thessaloniki 30 May-30 June 2000 31 Effect of radioprotective agent on qhromatin radiolysis V Preoteasa Adriana Costache Daria Mihalache Irina Radulescu 12th Balkan Biochemical Biophysical Days Bucharest May 10-13 2001 abstract book pg 83 32 Correlation between serum cholesterol level and DNA biosynthesis in liver cells Daria Mihalache V Preoteasa Irina Radulescu CT Dragomir 12th Balkan Biochemical Biophysical Days Bucharest May 10-13 2001 abstract book pg 63 33 Role of chromatin structure in UV laser radiolysis Preoteasa V Radu Liliana Radulescu Irina Martin C IV-th National Conference of Biophysics Abtra P-11 Cluj-Napoca 16-18 oct 1997 34 Normal and tumor cells chromatin st~ucture analysed by fluorimetric methods Liliana Radu V Preoteasa O Horer Doina Gazdaru XVI-Congress of the European Association of Cancer Recherch Thessaloniki 30 may-3 june 2000 35 Effect of radioprotective agent on centhromatin radiolysis V Preoteasa Adriana Costache Daria Mihalache Irina Radulescu 12th Balkan Biochemical Bioph~sical Days Bucharest May 10-13 2001 Abs Book p 83 36 Dependance de Iaction des neutrons rppides de la structure de la chromatine L Radu V Preoteasa B Constantinescu D Gazdaru Cinquieme Colloque International de Radiobiologie Fondamentale et Applique 18-22 juin 2001 37 Serum cholesterol level influencing t~e unscheduled DNA repair synthesis in rat hepatocyte Daria Mihalache Aura Carloban Alexandra Stanculescu V Preoteasa XXIVth Intern Congress of the Intern Acad Of Pathology abstr 17651 oct 2002 38 Microdosimetrie des radio lesions de la chromatine produites par les neutrons rapides L Radu V Preoteasa D Gazdaru B Constantinescu 6eme Colloque International de Radiobiologie Fondamentale et Applique 30 juin - 4 juillet 2003 Batz sur Mer 39 Special assays for chromatin DNA raqiation damage L Radu V Preoteasa B Constantinescu O Horer D Gazdaru 8th International Workshop Radiation Damage to DNA may 25-30 Alberta Canada 2004 40 Selenium and Vitamin E modulatory ~ffects on genomic DNA Double-Strand Breaks induced by chemical carcinogens in acute treatment in Wistar rats V Barc Daria Mihalache V Preoteasa acceptat la XXV Congress of the International Accademy of Pathology Brisbane Australia 10-15 Oct 2004 41 Spectrofluorimetric aspects of chromain gammalysis Preoteasa Vasile Vasile Gabriel J Daria Mihalache Barca Valentin Gheorghe Balasa - 4Th National Symposium of Pathology 31 oct-2 nov 2004 Bucharest 42 Spectrophotometric analysis of chromtin gammalysis V Preoteasa V Gabriel Daria Mihalache V Barca Gh Balasa - 8-th Romanian Biophysics Conference A~vanced Biomaterials and Biophysical Techniques may 26-28 2005 lasy Romania

Page 45 - Curriculum vitae of I Fo~ more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copyEiuropean Union 2004-2010 24082010

43 Chemical Modulation of Chromatin Gammalysis V Preoteasa G Vasile D Mihalache V Barca G Balasa The 15thshyIUPAB5th EBSA International Biophysics Cqngress Montpeliier France 01 092005 44 Incidence of radiation-induced micronucentlei in occupationally exposed subjects Daria Mihalache V Preoteasa Angela Petrescu Romanian J Biophys 17 (2)200( 45 Oxitocin receptor expression dynamics in human myometrium during pregnancy V Barca D Matei A Spataru Gabriela Barca V Preoteasa Daria Mihalache 3Th National Symposium of Pathology 31 oct-2 nov 2006 Bucharest 46 Liquid scintillation comparative ass~sssment of 3H bioaccumulation in two Sedum and Sempervivum species (Crassulaceae) co-inhabiting a central Dobtogean site Niculae M Barca V Varga A Zavidei V Nedescu L Jeledintan EM Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 47 ICP-MS comparative elemental analysis and bioconcentration capacity of two Sedum and Sempervivum species (Crassulaceae) Barca V Niculae M Varga A Zavidei V Nedescu L Jeledintan EM Matei D Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 48 Precise method for detection of metal traces in biological tissue V Preoteasa D Arsene V Barca F Mitu Daria Mihalache 4Th National Symposium of Pat~ology 31 10-211 2007 Bucharest 49 The frequency and morphological chwacteristics of interstitial Cajal cell-like in human leiomyoma Daria Mihalache V Preoteasa E Mandache Mihaela Gherghiceanu Maria Sajin Alina Chefani Anca Lazaroiu Elena Tianu 4Th National Symposium of Pathology 31 10-2112007 Sucharest 50 Zinc and other metals as factors invqlved in beta-amyloid peptide deposition in human brain A real role or random association D Arsene V Preoteasa A Balan S Tuta D Terzea F Vasilescu M Ceausu V Muntean A Anghel C Ardeleanu C losif I Alexandrescu C Pop$ 4Th National Symposium of Pathology 31 oct-2 nov 2007 Bucharest 51 The effect in vitro of the metotrexat ahd leflunomid on the pathologic monocytes from patients with rheumatic arthritis Neagoe lonela Victoria Balanescu Andra ~odica Preoteasa V Butur Georgeta Carolina Negrei Manda Gina 6th National Symposium of Pathology 3 - 5 november ~009 52 New nucleoside analogues conformatiqnally restricted with antitumor activity in vitro Neagoe lonela Victoria Preoteasa V Tanase Cristiana Postolache C Matei L Baconi DL Manda Gina AI 6-lea Simpozion National de Patologie 3 - 5 noiembrie 2009 53 Microelements accumulation in transgenic mouse tissues Preoteasa V Mitu F Neagoe lonela Victoria Savi G Savi

I

Ileana Geogia Daniela Butnariu Luminita qth National Symposium of Pathology 3 - 5 november 2009 54 Pro-inflammatory Signal delivered in vi~ro by leflunomide active metabolite A77 1726 on abnormal peripheral monocytes in rheumatoid arthritis Popa L Negrei C Neagoe IV Albulescu L Preoteasa V Balanescu AR Ghica MV Manda G Farmacia 58(5) 546-558 2010 IF 0144 ISSN 0014-8237 55 Early immune changes induced by Icentflunomide therapy in rheumatoid arthritis Manda G Neagoe IV Preoteasa V Balanescu AR Int Immunol 22 (Suppl 1) IpP036-45 2010 (14S1 Intemational Congress of Immunology 22-27 august 2010 Kobe Japonia) IF 3403 ISSN 0953-8178 56 Cellular immunity in rheumatoid art1ritis patients not responding to synthetic DMARDs Balanescu A Neagoe IV Berghea F Negrei C Parvu M lonescu R Predeteanu D Bojinca V Preoteasa V Manda G Arthrit isamp Rheumatism 62 (10shySuppl) S353 pg 848 (ACRARHP 201 0 A~nual Scientific Meeting 6-11 noiembrie 2010 Atlanta SUA) IF 7332 ISSN 1529shy0131 57 Trace metals as factors involved in hurnan neurodegeneration real rol or random association D Arsene V Preoteasa A Petrescu A Balan and C Ardeleanu Trflce Elements and Electrolytes vol 28 No42011 (221-231)

0111 2011 CS III Vasile Preoteasa

)0J~~~

Page 55 - Curriculum vitae of I For (lore information on Europass go to httpeuropasscedefop europaeu Preoleasa Vasile copy E~ropean Union 2004-2010 2408201 0

() ) ) ~ J

)N~

Page 4: e~ss - ivb.ro Preoteasa Vasile.pdf5. "Fluorescence lifetime, precision calorimetry and fluorescence energy transfer measurements in the study of normal and tumoral chromatin structure"

21 The action of an ultraviolet excimer laser radiation on rat Walker tumour chromatin structure n Radu Liliana Preoteasa V Stirbet M Horer 0 XVI International Cancer Congress New Delhi 30 oct-5 nov 1994 22 Fluorescence spectroscopy in the study of fast neutrons irradiation effects on liver chromatin structure Radu Liliana Hbrer 0 Constantinescu B Preoteasa V 6-th Eur Conf on the Spectroscopy of Biological Molecules Lille 3-8 sept 1995 23 Radioprotection de la chromatine par 1$ vita mine D3 et Ihormone thyroxine Radu Liliana Constantinescu BPreoteasa V Hbrer 0 Gostian Doina Lenghel Z Jo~rnees dEtudes de Chimie sous Rayonnement Orleans-Nouan-Ie-Fuzelier Volum

des Resumes F-18 19-24 mai 1996 24 A fluorescence energy transfer method for the study of protein-nucleic acid interactions Radu Liliana Hbrer 0 Preoteasa V XXIII Europ Congo on Molecular Spectroscopy Balatonfured Proceedings nr PA 17 pag 12025-30 aug 1996 25 The role of proteins and metal ions in the protection of chromatin DNA at fast neutrons action Radu Liliana Radulescu Irina Serbanescu Ruxandra B Constantin~scu V Preoteasa 27 th Annual Meeting of the European Society for Radiation Biology Montpellier Proceedings 320 pagi 34 1-5 sept 1996 26 The protection by proteins of chromqtin DNA against UV laser radiation Radu Liliana Preoteasa V Mihailescu I Radulescu Irina 12 th International Congress on Photobiology Viena Abstracts P 25 251 1-6 sept 1996 27 The laser irradiated chromatin structure studied by fluorescence spectroscopy Radu Liliana Radulescu Irina Serbanescu Ruxandra Preoteasa V Mihilescu I Lenghel Z 11-th Balkan Biophysical and Biochemical Days Salonic Grecia 15-17 mai 1997 28 UV laser radiosensitivity of normal ard tumour cells chromatin Radu Liliana Preoteasa V Radulescu Irina 28-th Annual Meeting of the European Society for iRadiation Research Oxfor Anglia 24-27 sept 1997 29 Spectrofluorimetric analysis of fast n~utrons action on chromatin influence of cytostatic and scavengers molecules Radu Liliana Radulescu Irina GazdaruDoina Constantinescu B Preoteasa V XXIV European Congress on Molecular Spectroscopy Praga 23-28 august 1998 30 Normal and tumor cells chromatin str~cture analysed by fluorimetric methods Liliana Radu V Preoteasa O Horer Doina Gazdaru 16th Congress of the Europyan Association of Cancer Research Thessaloniki 30 May-30 June 2000 31 Effect of radioprotective agent on qhromatin radiolysis V Preoteasa Adriana Costache Daria Mihalache Irina Radulescu 12th Balkan Biochemical Biophysical Days Bucharest May 10-13 2001 abstract book pg 83 32 Correlation between serum cholesterol level and DNA biosynthesis in liver cells Daria Mihalache V Preoteasa Irina Radulescu CT Dragomir 12th Balkan Biochemical Biophysical Days Bucharest May 10-13 2001 abstract book pg 63 33 Role of chromatin structure in UV laser radiolysis Preoteasa V Radu Liliana Radulescu Irina Martin C IV-th National Conference of Biophysics Abtra P-11 Cluj-Napoca 16-18 oct 1997 34 Normal and tumor cells chromatin st~ucture analysed by fluorimetric methods Liliana Radu V Preoteasa O Horer Doina Gazdaru XVI-Congress of the European Association of Cancer Recherch Thessaloniki 30 may-3 june 2000 35 Effect of radioprotective agent on centhromatin radiolysis V Preoteasa Adriana Costache Daria Mihalache Irina Radulescu 12th Balkan Biochemical Bioph~sical Days Bucharest May 10-13 2001 Abs Book p 83 36 Dependance de Iaction des neutrons rppides de la structure de la chromatine L Radu V Preoteasa B Constantinescu D Gazdaru Cinquieme Colloque International de Radiobiologie Fondamentale et Applique 18-22 juin 2001 37 Serum cholesterol level influencing t~e unscheduled DNA repair synthesis in rat hepatocyte Daria Mihalache Aura Carloban Alexandra Stanculescu V Preoteasa XXIVth Intern Congress of the Intern Acad Of Pathology abstr 17651 oct 2002 38 Microdosimetrie des radio lesions de la chromatine produites par les neutrons rapides L Radu V Preoteasa D Gazdaru B Constantinescu 6eme Colloque International de Radiobiologie Fondamentale et Applique 30 juin - 4 juillet 2003 Batz sur Mer 39 Special assays for chromatin DNA raqiation damage L Radu V Preoteasa B Constantinescu O Horer D Gazdaru 8th International Workshop Radiation Damage to DNA may 25-30 Alberta Canada 2004 40 Selenium and Vitamin E modulatory ~ffects on genomic DNA Double-Strand Breaks induced by chemical carcinogens in acute treatment in Wistar rats V Barc Daria Mihalache V Preoteasa acceptat la XXV Congress of the International Accademy of Pathology Brisbane Australia 10-15 Oct 2004 41 Spectrofluorimetric aspects of chromain gammalysis Preoteasa Vasile Vasile Gabriel J Daria Mihalache Barca Valentin Gheorghe Balasa - 4Th National Symposium of Pathology 31 oct-2 nov 2004 Bucharest 42 Spectrophotometric analysis of chromtin gammalysis V Preoteasa V Gabriel Daria Mihalache V Barca Gh Balasa - 8-th Romanian Biophysics Conference A~vanced Biomaterials and Biophysical Techniques may 26-28 2005 lasy Romania

Page 45 - Curriculum vitae of I Fo~ more information on Europass go to httpeuropasscedefopeuropaeu Preoteasa Vasile copyEiuropean Union 2004-2010 24082010

43 Chemical Modulation of Chromatin Gammalysis V Preoteasa G Vasile D Mihalache V Barca G Balasa The 15thshyIUPAB5th EBSA International Biophysics Cqngress Montpeliier France 01 092005 44 Incidence of radiation-induced micronucentlei in occupationally exposed subjects Daria Mihalache V Preoteasa Angela Petrescu Romanian J Biophys 17 (2)200( 45 Oxitocin receptor expression dynamics in human myometrium during pregnancy V Barca D Matei A Spataru Gabriela Barca V Preoteasa Daria Mihalache 3Th National Symposium of Pathology 31 oct-2 nov 2006 Bucharest 46 Liquid scintillation comparative ass~sssment of 3H bioaccumulation in two Sedum and Sempervivum species (Crassulaceae) co-inhabiting a central Dobtogean site Niculae M Barca V Varga A Zavidei V Nedescu L Jeledintan EM Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 47 ICP-MS comparative elemental analysis and bioconcentration capacity of two Sedum and Sempervivum species (Crassulaceae) Barca V Niculae M Varga A Zavidei V Nedescu L Jeledintan EM Matei D Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 48 Precise method for detection of metal traces in biological tissue V Preoteasa D Arsene V Barca F Mitu Daria Mihalache 4Th National Symposium of Pat~ology 31 10-211 2007 Bucharest 49 The frequency and morphological chwacteristics of interstitial Cajal cell-like in human leiomyoma Daria Mihalache V Preoteasa E Mandache Mihaela Gherghiceanu Maria Sajin Alina Chefani Anca Lazaroiu Elena Tianu 4Th National Symposium of Pathology 31 10-2112007 Sucharest 50 Zinc and other metals as factors invqlved in beta-amyloid peptide deposition in human brain A real role or random association D Arsene V Preoteasa A Balan S Tuta D Terzea F Vasilescu M Ceausu V Muntean A Anghel C Ardeleanu C losif I Alexandrescu C Pop$ 4Th National Symposium of Pathology 31 oct-2 nov 2007 Bucharest 51 The effect in vitro of the metotrexat ahd leflunomid on the pathologic monocytes from patients with rheumatic arthritis Neagoe lonela Victoria Balanescu Andra ~odica Preoteasa V Butur Georgeta Carolina Negrei Manda Gina 6th National Symposium of Pathology 3 - 5 november ~009 52 New nucleoside analogues conformatiqnally restricted with antitumor activity in vitro Neagoe lonela Victoria Preoteasa V Tanase Cristiana Postolache C Matei L Baconi DL Manda Gina AI 6-lea Simpozion National de Patologie 3 - 5 noiembrie 2009 53 Microelements accumulation in transgenic mouse tissues Preoteasa V Mitu F Neagoe lonela Victoria Savi G Savi

I

Ileana Geogia Daniela Butnariu Luminita qth National Symposium of Pathology 3 - 5 november 2009 54 Pro-inflammatory Signal delivered in vi~ro by leflunomide active metabolite A77 1726 on abnormal peripheral monocytes in rheumatoid arthritis Popa L Negrei C Neagoe IV Albulescu L Preoteasa V Balanescu AR Ghica MV Manda G Farmacia 58(5) 546-558 2010 IF 0144 ISSN 0014-8237 55 Early immune changes induced by Icentflunomide therapy in rheumatoid arthritis Manda G Neagoe IV Preoteasa V Balanescu AR Int Immunol 22 (Suppl 1) IpP036-45 2010 (14S1 Intemational Congress of Immunology 22-27 august 2010 Kobe Japonia) IF 3403 ISSN 0953-8178 56 Cellular immunity in rheumatoid art1ritis patients not responding to synthetic DMARDs Balanescu A Neagoe IV Berghea F Negrei C Parvu M lonescu R Predeteanu D Bojinca V Preoteasa V Manda G Arthrit isamp Rheumatism 62 (10shySuppl) S353 pg 848 (ACRARHP 201 0 A~nual Scientific Meeting 6-11 noiembrie 2010 Atlanta SUA) IF 7332 ISSN 1529shy0131 57 Trace metals as factors involved in hurnan neurodegeneration real rol or random association D Arsene V Preoteasa A Petrescu A Balan and C Ardeleanu Trflce Elements and Electrolytes vol 28 No42011 (221-231)

0111 2011 CS III Vasile Preoteasa

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Page 5: e~ss - ivb.ro Preoteasa Vasile.pdf5. "Fluorescence lifetime, precision calorimetry and fluorescence energy transfer measurements in the study of normal and tumoral chromatin structure"

43 Chemical Modulation of Chromatin Gammalysis V Preoteasa G Vasile D Mihalache V Barca G Balasa The 15thshyIUPAB5th EBSA International Biophysics Cqngress Montpeliier France 01 092005 44 Incidence of radiation-induced micronucentlei in occupationally exposed subjects Daria Mihalache V Preoteasa Angela Petrescu Romanian J Biophys 17 (2)200( 45 Oxitocin receptor expression dynamics in human myometrium during pregnancy V Barca D Matei A Spataru Gabriela Barca V Preoteasa Daria Mihalache 3Th National Symposium of Pathology 31 oct-2 nov 2006 Bucharest 46 Liquid scintillation comparative ass~sssment of 3H bioaccumulation in two Sedum and Sempervivum species (Crassulaceae) co-inhabiting a central Dobtogean site Niculae M Barca V Varga A Zavidei V Nedescu L Jeledintan EM Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 47 ICP-MS comparative elemental analysis and bioconcentration capacity of two Sedum and Sempervivum species (Crassulaceae) Barca V Niculae M Varga A Zavidei V Nedescu L Jeledintan EM Matei D Spataru A Preoteasa V National Biophysical Conference 11-14 may 2007 Bucharest 48 Precise method for detection of metal traces in biological tissue V Preoteasa D Arsene V Barca F Mitu Daria Mihalache 4Th National Symposium of Pat~ology 31 10-211 2007 Bucharest 49 The frequency and morphological chwacteristics of interstitial Cajal cell-like in human leiomyoma Daria Mihalache V Preoteasa E Mandache Mihaela Gherghiceanu Maria Sajin Alina Chefani Anca Lazaroiu Elena Tianu 4Th National Symposium of Pathology 31 10-2112007 Sucharest 50 Zinc and other metals as factors invqlved in beta-amyloid peptide deposition in human brain A real role or random association D Arsene V Preoteasa A Balan S Tuta D Terzea F Vasilescu M Ceausu V Muntean A Anghel C Ardeleanu C losif I Alexandrescu C Pop$ 4Th National Symposium of Pathology 31 oct-2 nov 2007 Bucharest 51 The effect in vitro of the metotrexat ahd leflunomid on the pathologic monocytes from patients with rheumatic arthritis Neagoe lonela Victoria Balanescu Andra ~odica Preoteasa V Butur Georgeta Carolina Negrei Manda Gina 6th National Symposium of Pathology 3 - 5 november ~009 52 New nucleoside analogues conformatiqnally restricted with antitumor activity in vitro Neagoe lonela Victoria Preoteasa V Tanase Cristiana Postolache C Matei L Baconi DL Manda Gina AI 6-lea Simpozion National de Patologie 3 - 5 noiembrie 2009 53 Microelements accumulation in transgenic mouse tissues Preoteasa V Mitu F Neagoe lonela Victoria Savi G Savi

I

Ileana Geogia Daniela Butnariu Luminita qth National Symposium of Pathology 3 - 5 november 2009 54 Pro-inflammatory Signal delivered in vi~ro by leflunomide active metabolite A77 1726 on abnormal peripheral monocytes in rheumatoid arthritis Popa L Negrei C Neagoe IV Albulescu L Preoteasa V Balanescu AR Ghica MV Manda G Farmacia 58(5) 546-558 2010 IF 0144 ISSN 0014-8237 55 Early immune changes induced by Icentflunomide therapy in rheumatoid arthritis Manda G Neagoe IV Preoteasa V Balanescu AR Int Immunol 22 (Suppl 1) IpP036-45 2010 (14S1 Intemational Congress of Immunology 22-27 august 2010 Kobe Japonia) IF 3403 ISSN 0953-8178 56 Cellular immunity in rheumatoid art1ritis patients not responding to synthetic DMARDs Balanescu A Neagoe IV Berghea F Negrei C Parvu M lonescu R Predeteanu D Bojinca V Preoteasa V Manda G Arthrit isamp Rheumatism 62 (10shySuppl) S353 pg 848 (ACRARHP 201 0 A~nual Scientific Meeting 6-11 noiembrie 2010 Atlanta SUA) IF 7332 ISSN 1529shy0131 57 Trace metals as factors involved in hurnan neurodegeneration real rol or random association D Arsene V Preoteasa A Petrescu A Balan and C Ardeleanu Trflce Elements and Electrolytes vol 28 No42011 (221-231)

0111 2011 CS III Vasile Preoteasa

)0J~~~

Page 55 - Curriculum vitae of I For (lore information on Europass go to httpeuropasscedefop europaeu Preoleasa Vasile copy E~ropean Union 2004-2010 2408201 0

() ) ) ~ J

)N~