esbl産生菌菌血症に対して piperacillin...
TRANSCRIPT
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ESBL産生菌菌血症に対してPiperacillin-Tazobactamは有効か?
~MERINO trial~
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症例提示 ADL自立の62歳女性
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症例提示
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症例提示
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EBMの実践 5 steps
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Step 1 疑問の定式化 (PICO)
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EBMの実践 5 steps
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Step 2 論文の検索
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EBMの実践 5 steps
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Background①
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Background②
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Background③
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Background④
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Research Question
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Method
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Study Design
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PICO
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Patient
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・
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研究ワークフロー
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Outcome
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・
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Sample Size
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Statistical Analysis
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Study Monitoring
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Result
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患者フローチャート
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研究が途中で中止となった理由
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患者背景
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~primary outcome~
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~secondary outcome~
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有害事象
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Microbiology
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Discussion
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Discussion
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Discussion
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内的妥当性の吟味
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外的妥当性の吟味
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Strength
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Limitation
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Limitation
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論文のまとめ
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今後の展望
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EBMの実践 5 steps
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研究患者は今回の患者と似ていたか
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患者に必要なoutcomeは全て考慮されたか
見込まれる治療の利益は考えられる害やコストに見合うか
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本症例の経過
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EBMの実践 5 steps
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Step 1-4の見直し
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Take Home Message