Epifager RegaleWhitening & Brightening Cream

New generation multi functional bio ingredients for radiant & bright skin

Epifager RegaleWhitening & Brightening Cream

Phyto agents for visible whitening - A natural approach to de-pigmentation

Belides - Bellis Perennis ( Daisy Flower ) Extract - 2%,

Getulina Whitening - Glycyrrhiza Glabra (Licorice) Root Extract, Aspergillus

Ferment & Ethoxydiglycol - 1.5%

I Emblica Extract - 1% I NanoWhite – 0.5% I SulforaWhite – 0.5% I Bismuth Oxychloride 0.5% I Pentavitine - 1% I

Epifager Regale Whitening & Brightening Cream

*Highly effective and safe – No toxicity /side effects when used on long term

*Controls Tyrosinase activity & Inhibits Melanin synthesis*Increase cell renewal

* Very fine texture, Highly absorbent & Non-comedogenic

Belides- Bellis Perennis

Bellis Perennis - Daisy flower extract is highly efficient natural skin lightening by influencing different

pathways involved in melanin formation.

It exhibits a strong inhibitory effect melanogenesis. The fraction of polyphenols is known to inhibittyrosinase enzymatic activity.

MelanogenesisHuman skin color pigment producing cells melanocytes are localized in the outermost layer of

the skin,the epidermis, to produce melanin. Upon exposure of the skin to UV radiation, melanogenesis is

enhanced by the activation of the key enzyme, tyrosinase.

Bellis Perennishas skin-lightening agent derived from daisy flowers. Its action is based on a

reduction of melanin activity, it provides even pigmentation and makes age spots less visible.

It is responsible for reduction of

I Tyrosinase expression & activity I Melanosome transfer* I Reduced color intensity

of age spots

I Safely inhibits the pigmentation process I Reduces melanin synthesis

*a melanin-producing granule in a melanocytes

Emblica exhibits strong anti-oxidant activity

Emblica fruit extract triple activity for skin brightening has many functional

properties a powerful cascading anti-oxidant used an age defying ingredient and

safe skin brightening agent help reduce acne & freckle spots ( Cluster ofconcentrated melanin).

Emblica Attributes

Uneven pigmentation is one of the most skin problems observed in Facial Artistry.

Based on emblica's performance in lightning freckles and its mechanism of activity, it would

show remarkable effects in age spot reduction.

Studies have confirmed that it's a natural substitute to Hydroquinone 1- 2 % which is widely

used as skin brightening agent.I Skin Brightening I Reduce hyperpigmentation I Anti freckle activity II Brightens I

I Tones skin natuarally I Super anti-oxidant I Broad spectrum anti-oxidant activity II Age defying I Collagenase inhibitor I Reduce superficial fine lines I

Emblica Vs Hydroquinone

GatulineGatuline Whitening, a natural complex consisting of Licorice

Extract, Kojic Acid, Lactic Acid and Aspergillus Ferment 

The kojic acid acts on the melanocytes to inhibit tyrosinage activity, Lactic acid enhances cell renewal and the penetration enhancer improves penetration

into the epidermis creating a reservoir at the dermal-epidermal junction.

Glabra (Licorice) Root Extract (and) Aspergillus Ferment (and) Ethoxydiglycol*Makes skin permeable for instant absorption .

Gatuline/ Mixture of Kojic acid & Lactic acid and Liquorice extract combined with a penetration enhancer, ethoxydiglycol.

Melanocytes are melanin producing cells locate in the bottom layer (the stratum basale of the skin's epidermis. Kojic acid works to  stop the production of melanin in the skin.

Melanin is the substance that gives the skin its pigment, and the more you have, the darker your skin will be. Age spots, sun spots & spots related to melasma and hyperpigmentation generally contain more melanin than

the surrounding healthy skin.

NanoWhite Triple activity for skin brightening

Whitening with natural Arbutin, Glutathione & Vitamin C

 

A Combination of Whitening Ingredients 

Bearberry leaves contain Arbutin which strongly inhibits tyrosinase activity.  

Arbutin is a natural derivative of Hydroquinone which is much more stable and safer than Hydroquinone

itself and so can be used regularly for a long period of time.

Glutathione is a tripeptide found in the human body. It is one of the skin's most powerful natural anti -oxidants but its level decreases with age. It inhibits tyrosinase activity due to its reduction potential.

Vitamin-C palmitate is the optimal form of Vitamin C for topical application. It combines anti-oxidant, anti

aging and whitening properties and can also lighten the existing dark spots. 

Double Effect on Human Tyrosinase Activity: The NanoWhite mechanism on tyrosinase activity was studied in-vitro tests. Assays were performed by using Normal Human Epidermal Melanocytes (NHEM) with different concentrations of NanoWhite against controls. The tyrosinas activity was determined by measuring themelanin content (optical density).

In the first study, tyrosinase was extracted from NHEM and incubated with NanoWhite. L-DOPA(enzyme substrate) was then added to start the tyrosinase reaction. Results showed a dosedependant inhibition of melanin formation. NanoWhite can thus directly inhibit tyrosinase activity.

NonoWhite can inhibit both the tyrosinase activity and the activation of enzyme.Thus, NanoWhite can regulate the tyrosinase activity and prevent pigmentation disorders.

Inhibition of Tyrosinase Activity

SulforaWhite Phyto

Sulforawhite Phyto Agent for visible whitening is liposomal preparation of Swiss garden

cress sprouts rich in sulforaphane a powerful anti-oxidant phytonutrient.

It effectively inhibits pigmentation by targeting two key upstream reaction steps in the

melanin cascade.

Pentavitin & Bismuth Oxychloride

Pentavitin is a highly effective moisturizer containing natural occurring carbohydrates, its composition is

similar to natural carbohydrate fraction found in stratum corneum of human skin.

Pentavitin acts as highly effective moisture regulator resulting in long lasting water retention in skin. 

Bismuth Oxychloride ( Ronaflair LF 2000) offers UV protection, unsurpassed smoothness & soft & gliding feel.

Epifager Regale Whitening & Brightening Cream

Description - Phyto agents for visible whitening & radiant skin, Reduce hyperpigmentation & act on the melanocytes to inhibit tyrosinage activity.

Indicated For - I Whitening & brightening skin I Uneven Pigmentation I Melasma I Dyscromia/Solar lightening

Pack : e 30g / 1.05 oz

Direction for use - Apply twice to clean , dry skin on the face & neck.

Skin Types - All Skin Types. Non comedogenic

Precautions - There may be slight tingling sensation which is very normal, however

Should there be any major irritation, please stop usage and consult your dermatologist.

Epifager Regale - Bio Ingredients and excipiens are from Merck, Germany, Gattefosse, France & Seppic,France!

Visible changes within two weeks of usage

* Application twice a day!Interesting Facts: Most of the normal darkening and discoloration of your skin is caused by the sun.

 Be patient: Skin becoming a fair color takes a long time. Depending on the damage done to your

skin, it can take anywhere between a few months or even longer. So Remember that consistency is the key

to facial treatments daily.

Typically, if you have only mildly tanned or burned skin, a few months should be adequate. But if the sun has been at your skin for hours and several days, be prepared to wait for little longer..

Thank you & all the best !Happy selling !