2005 27th Annual International

Conference of the IEEE

Engineering in Medicine and

Biology Society

Shanghai, China31 August - 03 September 2005

Volume 1 of 7

AlCCC IEEE Catalog Number: 0SCH37611

S '*~"" ISBN: 0-7803-8740-6

UB/TIB Hannover 89

Table of Contents

Introduction to IEEE-EMBS - What Can the Society Do for You? 1Barbara Oakley, Lisa Joanna Lazareck, Laura J. Wolf

Virtual Modeling of Compartmental Pharmacokinetic Systems 7

Manuel Prado, Laura M. Roa

Finite Element Modeling and Simulating ofAccommodating Human Lens 11

Zhuo Liu, Boliang Wang, XiuyingXu, YingJu, JiezhenXie, Chunbo Baa

Dynamic Model of the Aqueous Humor Circulation with Application to Simulation of the Treatment for Primary OpenAngle Glaucoma 15

YingJu, Boliang Wang, JiezhenXie, Liwei Huang, Shaohui Huang, XiaoyangHuang

Influence of Muscle Cooling on the Passive Mechanical Properties of theHuman Gastrocnemius Muscle 19Tetsuro Muraoka, Kohei Omuro, Taku Wakahara, Tetsuo Fukunaga, Kazuyuki Kanosue

Identification of Linear Time-Varying Systems Using Basis Pursuit 22

Sreemoyi Sanyal, Sunil' Kukreja, Eric Perreauh, David Westwick

Modelling for Computer Controlled Neuromuscular Blockade 26

Terence Gilhuly, Guy Dumont, BernardMacLeod

WaveShrink Using Modified Hyper-Shrinkage Function 30Poornachandra S, KumaravelN, Saravanan T. K, Somaskandan R

Effective Approach for Detecting the Single Trial ERP Using Rational Gaussian Neural Network 33

Minfen Shen, Yuzheng Zhang, Yisheng Zhu, Patch Beadle

Novel Method for Measuring the Complexity of Schizophrenic EEG Based on Symbolic Entropy Analysis 37

Ying Liu, Lisha Sun, Yisheng Zhu, Patch Beadle

An Improved Pre-Processing Approach for Photoplethysmographic Signal 41

Jianfeng Weng, Zhiqian Ye, Jianling Weng

Phase Coordination between Intracranial Pressure and Electrocardiogram Signals 45Xiao Hu, Marvin Bergsneidei; Valeriy Nenov

A Comparative Study on Microcalcifcation Detection Methods with Posterior Probability Estimation Based on

Gaussian Mixture Models 49Pablo Casaseca, Juan Ignacio Arribas, Emma Munoz-Moreno, Carlos Alberola-Lopez

A Model for Charged Molecule Transport in the Interstitial Space 55

Bin Chen, Bingmei Fu

Analyzing Effects of Sodium Pentobarbital on Hemodynamic Responses by Using a Graphic Control System 59

Chien-ya Hang, Jen-Yu Li, Te-Son Ktio, Fu-Shan Jaw

Analysis of ICG Pharmacokinetics in Cancerous Tumors Using NIR Optical Methods 62

Burak Alacam, Birsen Yazici, XavierIntes, Britton Chance

A Novel PBPK/PD Model with Automatic Nervous System in Anesthesia. 66

Hang Chen, Xuan Wang, Xinzhong Chen

Role of Sphingosine Kinase in the Expression ofAdhesion Molecules on Monocytes Induced by Tumor Necrosis Factor-

Alpha (Relevant to Atherosclerosis) 70

Chew Yan Tuang, Liang Zhong, Dhanjoo Ghista

On-Line Estimation ofPropofol Pharmacodynamic Parameters 74

Valentino Sartori, Peter Schumacher, ThomasBouillon, MartinLuginbuehl, ManfredMorari

Investigation on Biomedical Engineering Education ofthe Universities in US and UK 78

Haishu Ding, Yichao Teng, Datian Ye

Construction of a Knowledge Center for Medical Image Processing 82

Hui Ding, Guangzhi Wang, Bo Hong, Yiyi Zhou, Zhi Yang, MengMeng, Shangkai Gao

BME Education 5 Years at Zhejiang University • 86

Xiaoxiang Zheng, HuilongDuan, ShunrenXia, Yongguo Wang

On Talent Training ofMedical Equipment in Biomedical Engineering Field 89

Xuelong Zhang, MingyangLi, Ping Hu

Biomedical Imaging and Image Processing Course in Shanghai Jiao Tong University 93

Jim Zhao, Xiaoping Qian, YongfengHuang, YikangWang, TiangeZhuang

A Robot-Assisted Orthopedic Telcsurgery System 97

MinxiuKong, ZhijiangDu, Lining Sun, LixinFu, ZhihengJia, Dongmei Wu

Vital Signs Monitoring and Patient Tracking Over a Wireless Network 102

Matt Welsh, Greenspan Dan, Tia Gao, RadfordJuang, Alex Aim

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Table of Contents

Towards the Design of a Generic Systems Architecture for Remote Patient Monitoring 106

Tanja Maria Bratan, Malcolm Clarke

ECG Parameter Extractor of Intelligent Home Healthcare Embedded System 110

Weng Chi Chan, Shuo Tang, Sio HangPun, MangI Vai, Peng Un Mak

The Research ofTelemedicine System Based on Embedded Computer 114

Ping Wang, Jin-gang Wang, Xiao-bo Shi, Wei He

Impulse Initiation and Conduction in the Murine Atria: A Basis for Future Investigation of Sinus Node Dysfunction 118

Gregory Morley, Elvera Baron

The Effects ofHeptanol on Electrical Coupling During Ischemia in the Perfused Isolated Rat Heart 122

Hong-jiao Mao, Bao-ping Chen, Guang-yuan Ren, Jing-slnm Jin, Fang-yan Fan, Qin Gao, Iain C Bruce, QiangXia

The Effects ofK-Opioid Receptor Stimulation on Electrical Coupling During Ischemia in the Perfused Isolated Rat

Heart 126

Bao-ping Chen, Fang-yan Fan, Guang-yuan Ren, Jing-shun Jin, Hong-jiao Mao, Li-ping Wu, Iain C Bruce, Qiang Xia

Simulating Cardiac Ventricular Action Potentials in Rat and Mouse 130

Semahat Demir

Qualitative Support for the Gradient Model of Cardiac Pacemaker Heterogeneity 133

ShaunL Cloherty, Socrates Dokos, Nigel HLovell

Stability of Cardiac Action Potential Duration under Periodic Pacing 137

XiaodongHan, HailangSong, Xiaomei Wu, Cuiwei Yang, ZuxiangFang

Multiresolution Bayesian Detection of Multiunit Extracellular Spike Waveforms in Multichannel Neuronal Recordings 141

Karim Oweiss, Yasir Suhail

Optimal Rate Filters for Biomedical Point Processes • 145

James McNames

Inferring Attentional State and Kinematics from Motor Cortical Firing Rates 149

Frank Wood, Mr, Prabhat, John P. Donoghue, Michael J. Black

Automated Prediction of Epileptic Seizures in Rats with Recurrence Quantification Analysis 153

Gaoxiang Ouyang, LijuanXie, Huamven Chen, XiaoliLi, Xinping Guan, Huihua Wu

ICA Denoising for Event-Related FMRI Studies 157

Martin McKeown, Yong-jie Hu, Z. Jane Wang

Ensuring Patient Safety by Using Colored Petri Net Simulation of Quality of Service (QoS - IEEE 802.1 le) in the DesignofHeterogeneous, Multi-Vendor, Integrated, Life-Critical Wireless (802.1 lx) Patient Care Device Networks 162

Elliot B. Shane, VijayGehlot

Risk Management and Biomedical Devices 166

John Robson, Purdee Yeo, Mike Riches, Tony Carlisle, Noel Kitto

Survey of Clinical Engineering in Developing Countries and Model for Technology Acquisition and Diffusion 170

Moniqtte Prize, Xinyuan Cao, Isabelle Roy

Design ofComputerized Maintenance Management System for the Chilean Naval Hospital Biomedical EngineeringDepartment , 174

Francisco J. Acevedo, Jose Fuenies, John Enderle

Conceptual Design and Resources for a General Purpose Safety and Performance Validation Toolkit (V2T) for Life-

Critical Wireless Medical Device Networks (WMDN) 178

Elliot B, Shane, RickSchrenker

Issues ofDevice Safety in a Developing Country 182

Jih-Horn Stanley Chen, AlexKou, Wei-Shiang Lee

Medical Technology Mangemcnt: From Planning to Application 186

Yadin David, Ernest Gus Jahnke

Combined Photoacoustic and Molecular Fluorescence Imaging in Vivo 190

Lihong Wang, XueyiXie, Jung-Taek Oh, Meng-Lin Li, Geng Ku, Shi Ke, Sergiu Similache, Chun Li, George Stoica

High Resolution 3D Imaging of Lung Tissue Using Structured Light Microscopy 193

YmeAsgeir Kvistedal, Merr)m Tawhai, Peter Hunter, PoulNielsen

Continuous-Wave Near-Infrared Topography System and Its Clinical Applications 196

CanxingXu, Daifa Wang, Yonghong Zhang, JingBai

Imaging of Epithelial Cancer in Sub-Terahertz Electromagnetic Wave 199Kazutaka Mitobe, Motomu Manabe, Torn Kurabcyashi, Noboru Yoshimura

Time Resolved Optical Spectroscopy System for Cerebral Oxygenation Imaging 201Roman Maniewski, Adam Liebert, Michal Kacprzak

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Table of Contents

Optical Tomographic and Magnetic Resonance Imaging of Tumor Growth and Regression in Mice Treated with VEGF

Blockade,

205

James Masciotti, Gassan Abdoulaev, Frank Provenzano, Junho Hur, Joey Papa, Jae-0 Bae, J. Huang, Darrell Yamashiro,Jessica Kandel, Andreas Hielscher

Effects ofLarge Blood VesselLocations DuringHigh Intensity Focused Ultrasound Therapy forHepatic Tumors: A

Finite Element Study 209

Chenxi Zhang, Su Zhang, Zhao Zhang, Yazhu Chen

Dual-Frequency High Intensity Focused Ultrasound (HIFU) Accelerating Therapy 213

Pel Zhong He, Wende Shou, Shimei Duan, RongminXia

Characteristics of Photocytotoxicity with High Peak Power Pulsed Irradiation: Comparison of Photodynamic Therapywith Two Photosensitizers, Photofrin® and Mono-L-Aspartyl Chlorin E6 onProstate Cancer Cell in VUo 217

Sayaka Ohmori, Kensuke Masuda, Tsunenori Arai

Improvement of the Resonant Cavity Applicator for Brain Tumor Hyperthermia - Computer Simulation Results - 220

Takeshi Shigihara, Kazuo Kato, K. Tsuchiya, T.Yabuhara, T. Kohara, T. Uzuka, H. Takahashi, R. Tanaka

A Combinatorial Method for Predicting Genetic Susceptibility to Complex Diseases 224

Weidong Mao, Jingwu He, Dumitru Brinza, Alex Zelikovsky

Integrative Analysis ofMetabolic Disorders by Means of Medical Bioinformatics 228

Ming Chen, RalfHofestadt

Study on Chromatographic Data Pre-Processing Using Fuzzy Decision Making in Metabonomics 232

Jingqing Bai, Xiaohui Fan, Peng Shen

Sequence-based Protein-Protein Interaction Prediction Optimized for Target Selection in Biological Experiments 236

Jiankuan Ye, CasimirKulikowski, Ilya Muchnik

A Fast Algorithm Aligning Multiple Microbial Genomic Sequences 240

Gtiangyue Hu, Shi-Yi Shen

On the Alignment Space 244

Shi-Yi Shen, Kui Wang, GangHu, Lu-Sheng Chen, Hua Zhang, Shu-TaoXia

Development of a Portable Blood Sugar Apparatus and GOD Enzyme Strip ,248

Zhencheng Chen, Yuqian Zhao, Jingtian Tang, Lingyun Li

A Novel Lactate Biosensor 252

Jijun Tong, Jie Hu, Huang Zhongchao, Yuquan Chen, Min Pan

Study of Carbon Nanotube Modified Biosensors for Monitoring Uric Acid and Total Cholesterol in Blood 255

HuiXu, GuangLi, Min Fu, You Wang, Jim Liu

Development of a Novel Electronic Tongue System UsingSensor Array Based on Polymer Films for Liquid Phase

Testing 259

Xishan Guo, Yuquan Chen, Xianglong Yang, Liren Wang

The Assessment System ofHuman Visual Spectral Sensitivity Curve by Frequency Modulated Light 263

Yu-Pei Huang, Y.S. Huang, Ke-Nung Huang, M.S. Yang

Silica Nanoparticle Tags for Capacitive Affinity Sensors 266

AbhishekRamkumar, Rakesh Lai

Restoration ofNevoscopc Trans-Illuminated Images 270

Atarn Dhawan, Song Wang

An application of perturbation Monte Carlo in optical tomography 274

Julia KP Heiskala, Kalle Kotilahti, Ilkka Nissila

Near Infrared Imaging ofTissue Heterogeneity: Probe Design and Sensitivity Analysis 278

RonaldXu, Bo Qiang, Jimmy Mao

Application of Thermovision in the Assessment ofThermal Properthies Ophthalmic Viscoelastic Substances 282

Piotr Jurowslci, Grzegorz Owczarek, Grzegorz Gralewicz

Automated Detection Algorithm for Arteriolar Narrowing on Fundus Images 286

Yuji Hatanaka, Toshiaki Nakagawa, Yoshinori Hayashi, Akira Aoyama, Xiangrong Zhou, Takeshi Hara, Hiwshi Fujita, Yulaka

Mizukusa, Akihiro Fujita, Masakatsu Kakogawa

Frames-Based Denoising in 3D Confocal Microscopy Imaging 290

loannis Konstantinidis, Alberto Santamari-a-Pang, Ioannis Kakadiaris

Functional Imaging: Dynamic Contrast-Enhanced CT Using a Distributed-Parameter Physiologic Model for Accessing

Stroke and Intracranial Tumor •• 2"4

Lai Hong Cheong, Chong Kwee Tan, Tong San Koh, Tchoyoson CCLim, Sotirios Bisdas

A Real Time Simulation Model of Glucose-Insulin Metabolism for Type 1 Diabetes Patients 298

Stavroula Mougiakakou, Aikaterim Prountzou, Konstantina Nikita

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Computational Modeling of Vascular Clamping: A Step Toward Simulating Surgery 302

Henry Yu Chen, Daniel R. Einstein, Kinon Chen, Ivan Vesely

Pulmonary and Cardiovascular Integrated Model Controlled with Oxygen Consumption 304

Tatsuya Harada, Hajime Kubo, Taketoshi Mori, Tomomasa Sato

A Multi-Scale Model for the Selection Process of Ovulatory Follicles 308

Nki Echenim, Michel Sorine, Frederique Clement

Detecting Phase Coupling of Gastric Interdigestive Pressure Activity Via Diagonal Slice Spectra 312

Rongguo Yan, Guozheng Yan, Wenqiang Zhang, Long Wang

Increased Phase Synchronization between Intracranial Pressure and Arterial Blood Pressure During Elevated

Intracranial Pressure in Dogs 315

Rui Zou, Erin McCormack, Mike Egnor, Dong Kim, Bart MacDonald, Joseph Madsen, Mark Wagshul

Sensitivity of Detrended Fluctuation Analysis Applied to Heart Rate Variability of Preterm Newborns 319

GeertMorren, Philippe Lemmerling, Johannes Daniels, GunnarNaulaers, Sabine Van Hujfel

Intelligent Analysis ofBiosignals 323

Donna L Hudson, Maurice Cohen

Classification of Impulse Oscillometry Patterns ofLung Function in Asthmatic Children Using Artificial Neural

Networks 327

Miroslava Barua, Homayoun Nazeran, Patricia A. Na\>a, Bill Diong, Michael Dcn'id Goldman

Combined Bispectral and Bicoherency Approach for Catastrophic Arrhythmia Classification 332

AmjedAl-Fahoum, Labib Khadra

Simulation Study of Transmural Cellular Electrical Properties in Failed Human Heart 337

Yu zhang, GuofaShou, LingXia

Modeling Cardiac Activation and the Impact of a Discontinuous Myocardium 341

Mark Trew, Gregoiy Sands, Bryan Caldwell, Darren Hooks, Ian LeGrice, Bruce Smaill, Andrew Pullan

An Electrical Heart Model Incorporating Real Geometry and Motion 345

BenAppleton, Qing Wei, NianjunLiu, LingXia, Stuart Crozier, Feng Liu, Stephen Wilson

A Meshfrce Method for Solving Cardiac Electrical Propagation 349

Heye Zhang, Pengcheng Shi

Upgrading Undergraduate Biomedical Engineering Laboratory Training ., 353

Aris Tzavaras, Nikolaos Kontodimopoulos, Efstratia Monoyiou, loannis Kalatzis, Nikolaos Piliouras, Ilias Trapezanidis,Dionysios Cavouras, Errikos Ventouras

A Premier Comprehensive Curriculum in Biomedical Engineering within the Middle East and Northern African

Region 357

ZiadAbu-Faraj

The First Experience of a Dedicated Biomedical Education Unit at the University of Franchc-Comt6... 361

OlegBlagosklonov, Jean-Claude Cardot, Christophe Roux, Tijani Gharbi, Philippe Picart

Upgrading BME Studies in Buenos Aires, Argentine. Favaloro University 363

Ricardo Luis Armentano, Damian Craiem, Franco Martin Pessana, Sebastian Graf, Eduardo De Forteza

Clinical Application Driven Physiology in Biomedical Engineering Laboratory Course Education 367

Robert Schmidt

Ambulance 3G 371

Konstantinos Banitsas, Sapal Tachakra, Konstantinos Perakis, Dimilrios Koulsouris, Georgios Koimis

A PDA-Based ECG Beat Detector for Home Cardiac Care 375

Keng Wee Goh, LavanyaJanardhanan, Yongmin Kim, Eng Khoon Tan, Cheong Boon Soh

Medical Device Databases: A Scoping Study... 379

Sheila Price, Ronald Summers, David Williams

Information Flow and Data Reduction in the ECG Interpretation Process 382

Ryszard Tadeusiewicz, PiotrAugustyniak

Indoor Telemedicinc in Hospital: A PDA-Based Flexible Solution for Wireless Monitoring and Database Integration 386

Diego Salomon, Mauro Grigioni, Matteo Gianni, Micaela Liberti, Stefano De Luca, Andrea Bei, Guglielmo D'Inzeo

Scalable ECG Compression for Long-Term Home Health Care 390

Tong Zhang, Steven Simske, Daniel Blakley

Hemodynamic Performance In-Vivo ofa New Ventricular Assist Device 394

Farah Corona, Rodolfo Barragan, M. Calderon, Humberto Martinez, Oscar Infante, Molina Javier, Ma del Carmen Lespron,Angel Hernandez, Carlos Escobedo, Alicia Gorzelewski, Emilio Sacristan

Development of an Implantable and Ambulatory "Plug and Play" Transventricle LVAD 398

Dongfang Wang, Joseph B Zwischenberger, Xiaoqin Zhou, David Loran, Steven Topaz, KX Qian, Christoph Nix, Willem J Kolff

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Table of Contents

Detection and Avoiding Ventricular Suction of Ventricular Assist Devices 402Akira Tanaka.Makoto Yoshizawa, Paul Olegario, Daisuke Ogawa, K. Abe, T. Motomura, Stephen Igo, Y. Nose

Development of an Artificial Myocardium Using a Covalent Shape-Memory Alloy Fiber and Its CardiovascularDiagnostic Response 496Yasuyuki Shiraishi, T. Yambe, K. Sekine, N. Masumoto, J. Nagatoshi, S. Itoh, Y. Saijo, Q. Wang, H. Liu, S. Nitta, S. Konno, D.Ogawa, Paul Olegario, M. Yoshizawa, A. Tanaka, F. Sato, Y. Park, M. Uematsu, M. Higa, Y. Hori, T. Fujimoto, K. Tabayashi, HSasada, M. Umezu, D. Homma

Simulation of the Human Cardiovascular System for Real-Time Physical Interaction with an Assist Device 409Ben Mark Hanson, Martin Levesley, Kevin Watterson, Peter Walker

Artificial Gas Exchange 413Dongfang Wang, JosephB. Zwischenberger, SD Chambers

Information Rate of Neural Spike Trains in Response to Sinusoidal Electric Stimuli in the Presence of a Pseudo-

Spontaneous Activity 417HiroyukiMino

Quantifying the Contribution of Cross-Correlation in Stimulus Feature Discrimination in an Ensemble of RetinalGanglion Cells 421Wang QiangNht, Ai Hua Chen, Pei-Ji Liang, Jingqi Yuan

Signal Detection of Salient Visual Features by the Early Visual Pathway 425Nicholas Lesica, GarrettStanley

Spikes, Local Field Potentials, and Electrocorticogram Characterization During Motor Learning in Rats for Brain-Machine Interface Tasks.... 429

Timothy Marztillo, Johann Dudley, Charles Miller, Leonard Trejo, Daryl KipkeNeural Codes in Human Extracranial EEG: Identification ofEpilepsy Features 432

TaufikA. Valiante, Alan WingLim Chin, Berj LutherBardakjianA Computer Assisted Method for Guide-Wire and Catheter Evaluation 436Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Herman S. Bagga, Louis Kavoussi, Dan Stoianovici

Automated Leakage Current Measurement for Medical Equipment Safety 440

Yong Hu, LYPang, XBXie, XHLi, KDKLuk

Effects of Thrombolysis with Ultrasound on the Structure ofErythrocyte and Its Safety Threshold 443Yan Bige, Yang Yanni, Yuan Jiangang

Effects of Time-Varying Magnetic Fields on Transient Increase in Intracellular Ca2+ Concentration of Cultured Cells 446

Yusiike Uchigami, N. Kadowaki, T. Ikehara, H. Houchi, H. Yamaguchi, K. Yoshizaki, H. Miyamoto, Y. Kinouchi

Development and Transformation of Working Mode in Clinical Engineering Department 449Zhou Dan

Image Registration in Myocardial Perfusion MRI 453

Kelvin Wong, EdX. Wu, M. C. Ng, Y Wu, H. F. Tse, C. P. Lau, G. Lo, Edward Yang

Comparison of Point Similarity Measures for Atlas-Based Registration ofMRI Brain Images 455

Daniel Schwarz, Tomas Kasparek, Ivo Provaznik

A Segmentation Scheme ofBrainstem and Cerebellum Using Scale-Based Fuzzy Connectedness and Deformable

Contour Model 459

Jiann-Der Lee, Li-Chang Liu, Neng-Wei Wang, Chung-Hsien Huang, Chin-SongLu

Adaboost and Support Vector Machines for White Matter Lesion Segmentation in MR Images 463

Azhar Quddus, Paul Fieguth, Otman Basir

Image Segmentation, Registration and Visualization of Serial MR Images for Therapeutic AssessmentofPolycysticKidney Disease in Transgenic Mice 467

Baowei Fei, Chris Flask, Hesheng Wang, David Wilson, Jonathan Shillingford, Noel Murcia, Thomas Weimbs, Jeffrey Duerk, Ai

Pi

Intensity Robust Viscous Fluid Deformation Based Morphometry Using Regionally Adapted Mutual Information 470

Colin Studholme, Corina Drapaca, Valerie Cardenas

A New Thermal System for Tumor Treatment 474

Jianqi Sun, XiaodongLuo, Aili Zhang, LisaXueminXu

Numerical Calculations of Heating Patterns Around a Coaxial-Slot Antenna for Microwave Hyperthermia - Aiming at

Treatment of Brain Tumor and Bile Duct Carcinoma - • 478

Kazuyuh Saito, Satoru Kikuchi, Atsushi Hiroe, Masaharu Takahashi, Koichilto

Effective Cryopreservation of Human Embryonic Stem Cells by Programmed Freezing 482

Peng Fei Yang, Zezhao Hua, Xiaoqin Cong, Qikang Cheng, Yilin Cao

Performance Evaluation of a Novel Liquid Nitrogen Cryoprobe - 486

Shouliang Qi, Peng Zhang, Aili Zhang, Ruzhu Wang, LisaXueminXu

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Effect of Configuration between Cryoprobe and Large Blood Vessels on the Tissue Freezing During Cryosurgery 490

Zhong-Shan Deng, Jing Liu

The Cryopreservation of a Tissue Engineered Dermal Replacement by Programmed Freezing 494

CinEang, Zezhao Hua, Guanghui Yang, Lei Cut, WeiLiu, Yilin Cao

Self-Assembling of DNA and PAMAM Dendrimer 498

Linzhu Zhou, Xiangliang Yang, Lu Gan, HuibiXu

Highly Effective in Vivo Gene Transfection by Blocked Star Vector 501

Yue Min Zhou, Hal Ying Huang, Yasuhide Nakayama

Quantum Dots As Phototoxic Drugs and Sensors of Specific Metabolic Processes in Living Cells 504

Samuel Clarke, Jay Louise Nadeau, Daniel Bahcheli, Zhijun Zhang, Annette Hollmann

Visualization and Characterization of Drug Carrier Transportation and Distribution in Vivo 508

Fang Geng, Yuanyuan Shen, BaoweiPeng, Xiaohui Wei, LisaXuemin Xu, YuhongXu

Generation of Nanostructures of Mica Supported Lysozyme and Lysozyme-Nanogold Conjugates by Diving Tip

Nanowriting 512

Hans-AlbertKolb, FrankLeisten, Matthias Wiechmann, Oliver Enders

Novel Microarray Technology for Post-Genomic Studies 515

Zuhong Lu

Biolmplantable Bone Stress Sensor • 518

J. Fernando Alfaro, Gary K, Fedder, Lee E. Weiss, Phil G. Campbell, Mark C. Miller, Christa Heyward, John S. Doctor

Enhancement of an Electroporation System for Gene Delivery Using Electrophoresis with Planar Electrodes 522

Keng-Shiang Huang, Min Li, Chi-ChangSu, Hau-Hsuan Huang, Chun-Sheng Fang, Yu-ChengLin

Surface-Micromachined Neural Sensors with Integrated Double Side Recordings on Dry-Etch Bcnzocyclobutcnc(BCB)

Substrate 526

HaixinZhu, JipingHe, Bruce Kim

Droplet-Based Microtexture Biochip System for Triglycerides and Methanol Measurement 530

Ming-YuLin, Chih-ShengYu, Yi-Chiuen Hu, Shao-Chang Cheng, Heng-TsangHit

Detection of Vesicular Stomatitis Virus Using a Capacitive Immunosensor 534

Damn Hanna, Brooks Gross, Sachin Kandlikar, Elizabeth Lempicki, Barbara Oakley, Gabrielle Strykar

Phase Detection of the Two-Port FPW Sensor for Biosensing 538

Wen-Yang Chang, Yu-ChengLin, Wen-WangKe, Hsiao-LungNing, Po-Hsun Sung

From Codabar to ISBT 128: Implementing Barcode Technology in Blood Bank Automation System 542

BingNan Li, Ming Chui Dong, Mang I Vai

A Dynamic Blood Information Management System Based on RFID ....,..„ 546

MingJiang, PingFu, Hexin Chen, Mianshu Chen, Bo Xing, ZhonghuaSun, Ping Deng, Guang Wang, Yi Xu, Yu Wang

Integratting All Medical Records to an Enterprise Viewer 550

Haomin Li, Huilong Duan, Xudong Lu, Chenhui Zhao, Jiye An

The Design ofFormatted Report Language and Its Applications in Medical Information Systems 554

Xudong Lu, Huilong Duan, Zhengxin Huang, Ning Deng

A Workflow Based Self-Care Management System 558

Yunli Wang, Zhenkai Liu

HIPPA's Compliant Auditing System for Medical Imaging System ,562

Xiaomeng Chen, Jianguo Zhang, Wu Dongqing, Ruoling Han

Development and Validation of a 3D Clinostat for the Study of Cells During Microgravity Simulation 564

Gustavo Dalmarco, Thais Russomano, Ricardo Cardoso, Azevedo Dario, Celso Santos, Luis Gustavo Santos, Marlise Santos,

Leonardo Martinelli, JD Motta, Nico Forraz, Colin McGuckin, Felipe Falcao

Effects of Muscle Electrical Stimulation on Bone Mineral Density in the Hindlimb Bones of the Tail-Suspended Rats 567

Liang Peng, Jing Bai, Boyuan Sun, Guangzhi Wang, Wei Liu, Shuping Zhang, Ying Liang

Real-Time, Automatic Detection OfA Small Biomolccule Using The Novel Portable On-line Biomolccules Analyzer 569

Chunyan Wang, Jianghui Xiong, Yingjun Tan, YinglmiLi

Integrating Tclemonitoring with Clinical Information Systems: A Case Study 573

Matteo Cavalleri, Raul Morstabilini, Gianluigi Rent

Design and Implementation of Internet Based Healthcare Robot System 577

Dehuai Zeng, CunxiXie, Xuemei Li

Monitoring and Transmission Via Wireless Network for an Assistive Device 581

Yi-chu Chang, Chiun-fan Chen, Hua-sheng Lin, Jer-jimn Luh, Jin-shin Lai, Fok-ching Chong

Tele-Therapy System for Cognitive Disturbances 585

Jing Bai, Guangzhi Wang, Cheng Ouyang, Hui Ding

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Detection and Classification of Movements in Bed Using Load Cells 589AdrianaAdami, TamaraHayes, MichaelPavel, Clifford Milo SingerEvaluation of Patient-Centered Electronic Health Record to Overcome Digital Divide 593Eung-Hun Kim, Archana Mayani, Sneha Modi, Cheong Boon Soh, Yongmin KimEffect of Prolonged Pressure on Flowmotion: An Investigation Using an in Vivo Rat Model 597ZengyongLi, Eric W.C. Tarn, Maggie P. C. Kwan, Arthur F.T. Mak, Samuel C.L. Lo, Mason C.P. LeungCharacterization ofArterial Wave Propagation and Reflection in Mice 601Craig J. Hartley, Anilkumar K. Reddy, Sridhar Madala, MarkL. Entman, LloydH. Michael, George E. TaffetIs Aortic Impedance Altered in Dwarf Mice? 605Anilkumar K. Reddy, Thuy T. Pham, LloydH. Michael, George E. Taffet, Craig J. HartleyA Model-Based Numerical Analysis in the Early Development of Intracranial Aneurysms 607Yixiang Feng, Shigeo Wada, Ken-ichi Tsubota, Takami YamaguchiIn-Vitro Experimental Validation of Hemodynamics Study for ProximalAnastomosis Models 611ChuaLeokPoh, Zhang Junmei, Zhou Tongming, Tan YongSengInfluence of Aorto-Left Coronary Bypass Graft Geometry on Wall Shear Stress Distribution 615Meena Sankaranarayanan, Dhanjoo Ghista, LeokPoh Chua, Li Liu, YongSeng Tan

Cooling and Shielding Systems for Infrared Detectors -Requirements and Limits 619Boguslaw Wiecek

A Novel Approach ofAnalyzing the Relation between the Inner Heat Source and the Surface Temperature Distributionin Thermal Texture Maps .,623Chunfang Gao, Kaiyang Li, Shaoping Zhang

Thermography in Psoriasis Vulgaris Evaluation 627Anna Zalewska, Grzegorz Gralewicz, Grzegorz Owczarek, Boguslaw Wiecek

Facial Expression Recognition Using Thermal Image 631Guotai Jiang, Xuemin Song, Fuhui Zheng, Peipei Wang, Ashgan M. Omer

Visualisation of Medical Infrared Image Databases 634GeraldSchaefer, Shao Ying Zhu, Simon Ruszala

Optimization of MR-Relaxometry for BMD-Measurements and Its Correlation with DEXA 638

NaderRiyahi-Alam, Morteza Bakhtiary, MohammadAH Oghabian, AH Ghasemzadeh, Hossein Ghanaati, SaeedSarkar, BagherLarijani, Zahra Hamidy, NaserShaken

Dual-Modality PET-CT Visualization Using Real-Time Volume Rendering and Image Fusion with Interactive 3D

Segmentation ofAnatomical Structures 642

Jinman Kim, Tom Cai, D. G. Feng

The Role of Three-Dimensional Visualization in Surgical Planning ofTreating Lung Cancer 646

Yaoping Hu

Preliminary Study for Automated Recognition ofAnatomical Structure from Torso CT Images 650

Xiangrong Zhou, Takeshi Hara, Hiroshi Fujita, Ryujiro Yokoyama, TakujiKhyu, MassayukiKanematsu, HiroakiHoshi

Interactive Tooth Segmentation ofDental Models 654

Mingxi Zhao, Lizhuang Ma, Wuzheng Tan, Dongdong Nie

3D Visualization of Echocardiogram and Blood Flow 658Jun Wang, Nuan Zhao, Jianguo Yu, HaihongXue, Weiqi Wang

Slice-Based Prostate Segmentation in 3d Us Images Using Continuity Constraint 662

Mingyue Ding, Igor Gyacskov, Xiaping Yuan, Maria Drangova, DonalBernardDowney, Aaron Fenster

Optical Biosensors for Monitoring Dynamic Mass Redistribution in Living Cells Mediated by Epidermal GrowthFactor Receptor Activation 666

Ye Fang, Ann Ferrie, Norman Fontaine, Po Ki Yuen

Non-Invasive Monitoring ofHuman Cerebral Oxygen Saturation by Near Infrared Spectroscopy: Instrumentation,Calibration and Application in Cardiopulmonary Bypass 670

Yichao Teng, HaishuDing, Qingcheng Gong

The Establishment of an Automatic Separation System for Marine Meiobenthos 674

Junyi Yang, Dingli Li, Yi Pan, Shuming Ye, Shaojia Gao

Evaluation of a Capillary Measuring System for Characterisation ofSmall Tissue Samples by Impedance Spectroscopyat Higher Frequencies 678

Impidjati Impidjati, Hagen Thielecke, LeonardFransisca

Optimization of Off-Null Ellipsometry for Optical Biosensor Applications 682

Yan-Yan Chen, Yonghong Meng, Gang Jin

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Review on Thermal Image Processing for Passive and Active Thermography 686

Boguslaw Wiecek

Biomedical Applications ofFunctional Infrared Imaging 690

Arcangelo Merla, Gian Luca Romani

Noninvasive Multimodality Imaging Techniques to Assess Kaposi's Sarcoma 694

Amir H Gandjbakhche, Abby Vogel, FranckAmyot, Victor Chemomordik, Stavros Demos, Karen Aleman, RichardLittle, Robert

Yarchoan, Moinuddin Hassan

IMAGE ANALYSIS OF BREAST TUMORS USING THERMALTEXTURE MAPPING (TTM) 697

Yune Yuan, Qing Wang, SongSantai, LiJiye, ZhongqiLiu

Imaging Breathing Rate in the C02 Absorption Band 700

JinFei, Zhen Zhu, Ioannis Pavlidis

Role of IR-Thcrmal Imaging and Electroimpedance Measurements in Medical Diagnostics 706

Antoni Z. Nowakowski

Advanced Technique in Breast Thermography Analysis 710

Eddie YKNG, ECKee, AURajendra

Biomedical Nanotechnology for Molecular Imaging, Profiling, and Drug Targeting 714

GloriaJKim, Ruth MO'Regan, ShumingNie

Biomedical Applications Based on Core-Shell Nanoparticles 717Kemin Wang, Weihong Tan, Xiaoxiao He

Electrostatic Self-Assemble and Nanomedicine 720

Jian Ji, Jiacong Shen

Nanomolecular Histopathology for Renal Tumor Classification 723Andrew Young, ShumingNie, May Dongmei Wang, JohnPetros, Michael J. Natan, MahulB. A min

Spatial and Temporal Hemodynamic Study of Human Primary Visual Cortex Using Simultaneous Functional MRI and

Diffuse Optical Tomography 727

Xiaofeng Zhang, Vladislav Y. Toronov, Andrew G. Webb

Triple/Single Quantum Filtered Sodium MRI of Acute Brain Ischemia 731

Fernando Boada, George LaVerde, Charles Jungreis, Edwin Nemoto, Costin Tanase

Parallel MR Imaging with Accelerations Beyond the Number of Receiver Channels Using Real Image Reconstruction 735JimX. Ji, Steven M, Wright

Estimating Evolutionary Rate of Local Protein Binding Surfaces: A Bayesian Monte Carlo Approach 739Yan Yuan Tseng, Jie Liang

The Cancer Biomedical Informatics Grid (caBIG) 743DavidFenstermacher, Craig Street, Tara McSherry, VishalNayak, Case)> Overby, Michael Feldman

Design ofa Genetic Differential Amplifier 747SeemaNagaraj, Stephen William Davies

Update on the Pfam5000 Strategy for Selection ofStructural Genomics Targets 751John-Marc Chandonia, Steven E. Brenner

Biocomplexity ofRespiratory Neural Network During Early Maturation 756Metin Akay

Chaotic Dynamics of Ventilatory Flow in Humans 759Marc Wysocki, Maiie-Noelle Fiamma, Christian Straus, Chi-SangPoon, Thomas Similowski

Signal Processing and Modelling for the Complex Cardiorespiratory Interactions 763Sergio Cerutti

Nonlinear Interaction of Voluntary Breathing and Cardiovascular Regulation 764Guoqiang Wu, JibinXin, LishuaiLi, Cheng Li, YongFang, Chi-Sang Poon

Fibrillation Complexity As a Predictor of Successful Defibrillation 768Naresh Bqjaj, Josh Leon, Shane Kimher, Edward VigmondWireless Real-Time Head Movement System Using a Personal Digital Assistant for Control of a Power Wheelchair 772DanielAshley Craig, HungNguyen

Noninvasive Assessment of Cardiovascular Autonomic Control in Pediatric Obstructive Sleep Apnea Syndrome 776Zheng Lin, Maida Chen, Thomas Keens, Sally Davidson Ward, Michael Khoo

Adaptive Change Point Detection for Respiratory Variables 780Ping Yang, Guy Dumont, Joanne Lim, J. Mark Ansermino

Computer-Assisted Ankle Joint Arthroplasty Using Bio-Engineered Autografts 784Rudolf Sidler, Miguel Angel Gonzalez Ballester, Martin Styner, Thibaut Bardyn, Lutz-Peter Nolle, Norbert Sudkamp, WolfgangKostler

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A Wavelet Approach to Detecting Electrocautery Noise in the ECG 788Christopher Brouse, GuyDumont, Felix Hemnamt, J. Mark Ansermino

A Viral Envelope As a Vehicle for Tracer, Drug, and Gene Delivery: Initial Biodistribution Study Using PET Imaging 793Jennifer A. Flexman, Satoshi Minoshima, Yongmin Kim, Sosuke Miyoshi, Barbara L. Lewellen, Donna J Cross

Automated Image Analysis of Fluorescence Microscopic Images to Identify Protein-Protein Interactions 797Sankar Venkataraman, Jennifer Morrel-Falvey, Mitchel Doktycz, Hairong QiTools for Modelling Biological Systems with CellML 801Matt Halstead, Poul Nielsen

A Novel Method for Creating a 2-D Parameterized Finite Element Model of the Human Femurwith Matching ArtificialHip Joint Based on X-Ray Image 805Kai Tao, Ai li Qu, Dongmei Wang, Chengtao Wang

Evaluating Estimates ofMarkov Models of Sequence Evolution through Simulation 808

Keyuan Xu, George Verghese, Peter C. Doerschuk

Bioinformatic System Modeling on Hetian Uygur Natural Longevity People 813Shangshang Sun, Xiaohui Zhang, Yanchi Zhang, Haiyun Wang, Yongsui Yu, Mingjiang Zhang3D CT-Imaging for Craniofacial Analysis Based on Anatomical Regions 817Wan Abdul Rahman WanHarun, Zainul AhmadRajion, Izhar AbdulAziz, Ah Rani Samsudin

Mathematical Analysis of the HTV-1 Infection : Parameter Estimation, Therapies Effectiveness and TherapeuticalFailures

821Djomangan Adama Ouattara

A Novel Spectral Analysis Method of Atrial Fibrillation Signal Based on Hilbert-Huang Transform 825Zhongchao Huang, Jijun Tong, Yuquan Chen, Min Pan

Novel Approach for Time-Varying Bispectral Analysis of Non-Stationary EEG Signals 829Minfen Shen, Ying Liu, Heyan Chan, Patch Beadle

Analyze the Dynamic Features of Rat EEG Using WaveletEntropy 833

Zhouyan Feng, Hang Chen

Effects of Extremely Low Frequency Electromagnetic Fields on Electrocardiogram: Analysis with Quadratic Time-Frequency Distributions 837

SeedahmedMahmoud, QiangFang, Irena Cosic, Zahir Hussain

Adaptive Spectrogram for Surface EEnG Analysis 841Javier Garcia-Casado, Jose Luis Martinez-de-Juan, Gema Prats-Boluda, Julia Bertelli, Jose Luis Ponce

GLUCOSIM: Educational Software for Virtual Experiments with Patients with Type 1 Diabetes 845Boris UgurAgar, MeriyanEren, All Cinar

Internet Applications for Computational Biology, the CMISS Web Browser Extension and and Use in Education 849

Carey Stevens, Shane Allan Blackett, IanLeGrice, Peter Hunter

SIMULATION-BASED TRAINING IN ELECTROPHYSIOLOGY BY Icell 851Semahat Demir

Building Interactive Simulations in Web Pages withoutProgramming 855

JMailen Kootsey, Grant McAuley, Julie Bernal

Physiological Signal Processing Laboratory for Biomedical Engineering Education 859Alan Macy, Steve Carmel

Simple Analog Models to Teach Electrophysiological Concepts 863

FeritPehlivan

Improving the Classification ofCirrhotic Liver by Using Texture Features 867

Xuejun Zhang, Hiroshi Fujita, Massayuki Kanematsu, XiangrongZhou, Takeshi Hara, HirokiKato, Ryujiro Yokoyama, Hiroaki

Hoshi

An Analysis of Chirpp Data to Predict Severe ATV Injuries Using Artificial Neural Networks 871

Yonca Erdebil, Monique Prize

A Real-Time Continuous Cardiac Arrhythmias Detection System: RECAD 875

HaiyingZhou, Kun-Mean Hou, Jean Ponsonnaille, Laurent Gineste, ChristopheDe Vaulx

Automated Individual Prescription ofExercise with an XML-Based Expert System 882

SeungJin Jang, Serim Park, Yong GuJang, JiEun Park, Seung-Hun Park, Young-ro Yoon

Hybrid Data Mining Ensemble for Predicting Osteoporosis Risk 886

Wenjia Wang, Sarah Rea, Graeme Richards

A Scmi-Automatic Orthopedic Implant Management Tool for Computer Assisted Planning, Navigation and Simulation:

From XML Implant Database to Unified Implant Access Interface 890

Serge Sagbo, Francois Blochaou, Frank Langlotz, Christelle Vangenot, Lutz-Peter Nolte, Guoyan Zheng

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Gene Expression Data for DLBCL Cancer Survival Prediction with a Combination of Machine Learning Technologies 894

RuiXu, Xindi Cai, Donald Wunsch

An Automatic and Power Spectra-Based Rotate Correcting Algorithm for Microarray Image 898

NingDeng, Huilong Duan

Improved Probe Selection for DNA Arrays Using Nonparamctric Kernel Density Estimation 902

QiFu, James Borneman, Jingxiao Ye, MarekChrobak

Finding Co-Clusters of Genes and Clinical Parameters 906

Sungroh Yoon, Luca Benini, Giovanni De Micheli

The Response of the Metabolic Network of the Red Blood Cell to Pyruvate Kinase Deficiency 913

Xiaoliang Sun, Zuhong Lu

Effect ofOutlier Removal on Gene Marker Selection Using Support Vector Machines 917

Richard Moffitt, JohnPhan, Scott Hemby, MayDongmei Wang

Selective Quantification of Cardiac Sympathetic and Parasympathetic Nervous Function from Non-Invasive

Measurements 921

Rafat Elahi, Ramakrishna Mukkamala

Insignificant Effects of Plasma Catecholamines on Dynamic Heart Rate Regulation by the Cardiac Sympathetic Nerve 925

ToruKawada, Masashi Inagaki, Can Zheng, MeihuaLi, Kenji Sunagawa, Masaru Sugimachi

Carvedilol Protects Early Diabetic Rat Hearts through Reducing Oxidative Stress 929HeHuang, Jiang Shan, Xiao-Hong Pan, Xiao-Feng Bao, Ling-Bo Qian, QiangXia

Modelling Cardiac Dynamics with Integral Pulse Frequency Modulated Units 933David Chik, Adelle C F Coster

An Efficient Algorithm to Reconstruct Heart Rate Signal Based on an IPFM Model for the Spectral Analysis of HRV 936Fei Chen, Yuan-Ting Zhang

Multiple Factor Analysis of the Autonomous Nervous System During PTCA 940Camilo Noel Castro, AdolfEngels Medina, Pedro Gomis, Sara Wong, Galen Wagner

A New Muscle Artifact Removal Technique to Improve the Interpretation of the Ictal Scalp Electroencephalogram 944Wim De Clercq, Anneleen Vergult, Bart Vanrumste, Johan Van Hees, Andre Palmini, Wim Van Paesschen, Sabine Van HuffelRule-Enhanced Clustering in the Detection of Neonatal Seizures 948

Joyeeta Mitra, John R. Glover, Periklis Y. Ktonas, James D. Frost, Richard A. Hrachovy, Eli M. Mizrahi

Intracranial Electrode Visualization in Invasive Pre-Surgical Evaluation for Epilepsy 952Yunhua Wang, RajeevAgarwal, DangNguyen, VirgilDomocos, Jean Gotman

On the Use ofSpectrally Constrained TCA Applied to Single-Channel Ictal EEG Recordings within a DynamicalEmbedding Framework 956

ChristopherJames, Christian Hesse

Effectiveness ofDaily Short-Duration Standing in Preventing Post-Suspension Cardiovascular Dysfunction in Rats

Assessed by Cardiovascular Signal Analysis 960Xin Liu, Jiuhua Chen, HongbingLu, Li-Fan Zhang

Protection ofForce Incentive on Bone Lose of Tail-Suspended Rats 964Yumin Wan, Yongjie Ma, Xiaoyou Zhang, Honghui Wang, Yue Liu, Yinghui Li

The Role ofERK in Phasic and Tonic Contractile Responses in Rat Femoral Arteries after Hlndlimb Unloading 967Ming Yuan, ZhiliLi, Desheng Wang, ShizhongJiangA Preliminary Biophysical Report on the Fertilized Eggs Traveled with Spaceflight , 971Wei Chen, Wei Wang

Elastographic Imaging of the Strain Distribution at the Anterior Cruciate Ligament and ACL-Bone Insertions 972ElisaKonofagou, Jeffrey Spalazzi, Helen Lu

Fast Reconstruction of Tissue Elastic Modulus Image by Ultrasound 976Tsuyoshi Shiina, Makoto Yamakawa

Reconstruction of Shear Modulus Distribution Together with Poisson's Ratio Distribution and Density Distribution 981Chikayoshi Sumi

A Theoretical Model for Myocardial Elastography and Its in Vivo Validation 985Elisa Konofagou, Wei-NingLee, CM. Ingrassia

Development of a Synchronized System for Continuous Acquisition and Analysis of Ultrasound Joint Angle, and EMG 989Qinghua Huang, Yongping Zheng, Xin Chen, Jun Shi

A Novel Method to Obtain Modulus Image of Soft Tissues Using Water Jet Compression 993Minhua Lu, YongpingZheng, Qinghua Huang

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A Correlation Study on the Variabilities in Pulse Transit Time, Blood Pressure, and Heart Rate Recorded

Simultaneously from Healthy Subjects 996

Ting Ma, Yuan-Ting Zhang

Development ofa Wearable Measurement and Control Unit for Personal Customizing Machine-Supported Exercise 1000

Zhihui Wang, Naoki Tamura, Tohru Kiiyu

Development of a Wearable Device Capable ofMonitoring Human Activity for Use in Rehabilitation and Certification

ofEligibility forLong-Term Care 1004

Kosuke Motoi, Yuji Higashi, Yutaka Kuwae, Tadahiko Yuji, Shinobu Tanaka, Ken-ichi Yamakoshi

A Smart Orthosis for the Treatment of Scoliosis 1008

EdmondH. Lou, James Raso, Christopher Chan, Doug Hill, Marc Moreau, James Mahood, Andreas Donauer

Wearable Kinesthetic Systems for Capturing and Classifying Body Posture and Gesture 1012

Alessandro Tognetti, Federico Lorussi, Mario Tesconi, Raphael Bartalesi, Giuseppe Zupone, Danilo De Rossi

Wireless Hearing Aid System Simulations Using Advanced Design System: A Behavioral Modeling Approach 1016

Ram Singh Rana, Bin Tang, Liang Zhang, Hari Krishna Garg, De Yun Wang

Experimental Study of Two-Frequency Dielectrophoresis Effects on a Linear Electrode Array 1020

YantingZhang, FredericBottausci, Noel MacDonald, IgorMezic

A Micro Device for Separation of Erythrocytes and Leukocytes in Human Blood 1024

Siyang Zheng, Yu-Chong Tai, Harvey Kasdan

Integrated Flexible Ocular Coilfor Power and Data Transfer in Retinal Prostheses 1028

Wen Li, Damien C. Rodger, James Wetland, Mark Humayun, Yu-Chong Tai

High Quality Performance of High-Throughput GeneChip® Probe Array System ,. 1032

Zuwei Qian, Han Wang, KomalSingh, Govinda Rao, MatthewHo, Thomas Ryder

NTA-Functionalized Poly(L-Lysine)-G-Poly(Ethylene Glycol): A Polymeric Interface for Binding and Studying 6xHis-

Tagged Proteins 1036

Guoliang Zhen, Stefan Zurcher, Didier Falconnet, FeiXu, Eva Kuennemann, Marcus Textor

In Vivo Detection ofNitric Oxide in Rat Hippocampus 1039

Kezhou Liu, Gangmin Ning, XiaoxiangZheng

A Highly Responsive System for On-Line in Vitro Assessment of Tissue Growth within Micro-Porous Polymer Scaffolds 1043

Dariusz Dziong, Pierre Bagnaninchi, Maryam Tabrizian, Robert EdwardKearney

BAEC Adhesion Analysis Using Thickness Shear Mode Sensor 1047

Soonjin Hong, Ertan Ergezen, Kenneth A. Barbee, RyszardLec

Numerical Design and Experimental Analysis of Cell-Based Sensors 1051

Hua Cai, Lifeng Qin, Qingjun Liu, YingXu, RongLi, Ping Wang

High Frequency Electrically-Induced Force Generation by Cellular PlasmaMembranes 1055

Bahman Anvari, Feng Qian, FredA. Pereira, William Brownell

Microfabricated Cell-Based Biosensor Arrays 1058

Michael Pishko

Effects of Cardiac Anisotropy on Three-Dimensional Inverse Activation TimeImaging: A Celhuar-Automaton-Based

Model Study 1065

ChenguangLiu, Bin He

Imaging ofBioelectric Sources in the Heart Using a Cellular Automaton Model 1067

OlafDoessel, Dmytro Farina, W.R. Bauer, C. Kaltwasser, O. Skipa

Simulation of Intracardial Potentials with Anisotropic Computer Heart Models 1071

Xin Zhu, Darning Wei, Hui Wang

Multiple Dipole Sources Localization from the Scalp EEG Using a High-Resolution Subspace Approach 1075

Lei Ding, Bin He

Hybrid Weighted Minimum Norm Method a New Method Based LORETA to Solve EEG Inverse Problem 1079

Chaoyun Song, Tiange Zhuang, Q. Wu

Visualization and Post-Processing of 5D Brain Images 1083

Yan Zhang, Peter Jonathan Passmore, RichardH Bayford

Ultrasonic Imaging of Myocardial Vibrations Associated with Coronary Artery Disease 1087

Siddhartha Sikdar, YongminKim, Steven Goldberg, ToddZwink, Linda Baughman, KirkBeach

Evaluation of Patient-Centered Electronic Health Record to Overcome Digital Divide 1091

Eung-HunKim, ArchanaMayani, SnehaModi, CheongBoonSoh, YongminKim

Recovery of Metabonomic Spectral Sources Using Non-Negative Matrix Factorization 1095

Shuyan Du, Paul Sajda, Radka Stoyanova, Truman Brown

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