Emetic & Anti emetic Drugs

Cerebral Centers Affecting Vomiting

Vomiting (cont’d)

• Nonpharmacologic measure

• Nonprescription antiemetics– Antihistamines– Bismuth subsalicylate– Phosphorylated carbohydrate solution

Prescription Antiemetics

• Prescriptive antihistamines

• Anticholinergic

• Dopamine antagonists– Phenothiazines– Butyrophenones– Metoclopramide

Prescription Antiemetics (cont’d)

• Benzodiazepines

• Serotonin receptor antagonist

• Glucocorticoids

• Cannabinoids

• Miscellaneous– Diphenidol, droperidol, trimethobenzamide

Emetics

• Ipecac is an OTC drug• Administration

– Take with a glass of water or fluid, not with milk or carbonated beverage

– Vomiting occurs in 20 to 30 minutes and if not, repeat dose

– Gastric lavage may be needed if vomiting does not occur

• Caution: avoid vomiting if substance is caustic or petroleum