Planta MedicaJournal of Medicinal Plant and Natural Product Research

Editors-in-ChiefOliver Kayser, Dortmund, GermanyRobert Fürst, Frankfurt, Germany

EditorsAlessandra Braca, Pisa, ItalyAlexander Crawford, Oslo, NorwayElke Heiss, Vienna, AustriaOlivier Potterat, Basel, SwitzerlandJose-Luis Rios, Valencia, SpainJudith Rollinger, Vienna, Austria

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Matthias Melzig, Berlin, GermanyEduardo Munoz, Cordoba, SpainNicolas H. Oberlies, Greensboro, NC, USAPeter Proksch, Düsseldorf, GermanyPing-Jyun Sung, Pingtung, TaiwanDeniz Tasdemir, Kiel, GermanyMichał Tomczyk, Białystok, PolandHeikki Vuorela, Helsinki, FinlandJean-Luc Wolfender, Geneva, SwitzerlandYang Ye, Shanghai, China

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Editorial Board

Planta Med 2019; 85

Planta MedicaVolume 85Planta Medica is published in 18 issues per year.ISSN (Print): 0032-0943eISSN: 1439-0221

Editors-in-ChiefProf. Dr. Robert FürstGoethe UniversitätInstitut für Pharmazeut. BiologieGeb. N230 / Raum 3.06Max-von-Laue-Str. 960438 Frankfurt

Prof. Dr. Oliver KayserEmil-Figge-Str. 6644227 Dortmund

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Masthead

Planta Med 2019; 85

Contents III

Planta Med 2019; 85

    

  Issue 1  (January 2019) = Page 5   –I  –

87IV

 

  Issue 2  (January 2019) = Page 93   – 178   Issue 3  (February 2019) = Page 185   –

e1  –265

e1 

  Issue 4  (March 2019) = Page 273   – 355   Issue 5  (March 2019) = Page 360   – 438   Issue 6  (April 2019) = Page 444   – 518   Issue 7  (May 2019) = Page 523   – 614   Issue 8  (May 2019) = Page 619   – 688   Issue 9/10  (July 2019) = Page 692   –

e2  –796

e2 

  Issue 11/12 (August 2019) = Page 800   – 1039   Issue 13  (September 2019) = Page 1044   – 1123   Issue 14/15 (October 2019) = Page 1128   – 1186   Issue 16  (November 2019) = Page 1192   – 1286   Issue 17  (November 2019) = Page 1291   – 1382   Issue 18  (December 2019) = Page 1386   – 1387 

67^th International Congress and AnnualMeeting of GA

    

1386 Abstract Issue

Biological and Pharmacological Activity    

6 Abrahams, Sameega, Sedicka Samodien, Mariska Lilly,Elizabeth Joubert, Wentzel GelderblomDifferential Modulation of Gene Expression EncodingHepatic and Renal Xenobiotic Metabolizing Enzymes byan Aspalathin-Enriched Rooibos Extract and Aspalathin

379 Ahoua, Angora Rémi, Aymeric Monteillier,Frédéric Borlat, Olivier Ciclet, Laurence Marcourt,Samad Nejad Ebrahimi, Mamidou Witabouna Koné,Bassirou Bonfoh, Philippe Christen, Muriel CuendetAnti-inflammatory and Quinone Reductase-InducingCompounds from Beilschmiedia mannii

312 Balogun, Fatai Oladunni, Anofi Omotayo AshafaA Review of Plants Used in South African TraditionalMedicine for the Management and Treatment ofHypertension

701 Basnet, Buddha Bahadur, Li Liu, Baosong Chen,Yerlan Melsuly Suleimen, Haiyang Yu, Shouyu Guo,Li Bao, Jinwei Ren, Hongwei LiuFour New Cytotoxic Arborinane-Type Triterpenes fromthe Endolichenic Fungus Myrothecium inundatum

239 Benny, Anju, Jaya ThomasEssential Oils as Treatment Strategy for AlzheimerʼsDisease: Current and Future Perspectives

947 Benteldjoune, Mounira, Maria Giovanna Chini,Anna Maria Iannuzzi, Ahmed Kabouche,Zahia Kabouche, Massimiliano DʼAmbola,Stefania Marzocco, Giuseppina Autore,Giuseppe Bifulco, Nunziatina De TommasiGuaianolides from Ormenis mixta: Structural Insightsand Evaluation of Their Anti-inflammatory Profile

840 Bottone, Alfredo, Antonietta Cerulli, Gilda DʼUrso,Milena Masullo, Paola Montoro, Assunta Napolitano,Sonia PiacentePlant Specialized Metabolites in Hazelnut (Corylusavellana) Kernel and Byproducts: An Update onChemistry, Biological Activity, and Analytical Aspects

1225 Bouslama, Lamjed, Bochra Kouidhi,Yasir Mohammed Alqurashi, Kamel Chaieb,Adele PapettiVirucidal Effect of Guggulsterone Isolated fromCommiphora gileadensis

815 Bruno, Maurizio, Vincenzo Ilardi, Giulio Lupidi,Luana Quassinti, Massimo Bramucci, Dennis Fiorini,Alessandro Venditti, Filippo MaggiThe Nonvolatile and Volatile Metabolites of Prangosferulacea and Their Biological Properties

1351 Cacabelos, Ramón, Iván Carrera, Ramón Alejo,Lucía Fernández-Novoa, Pablo Cacabelos, Lola Corzo,Susana Rodríguez, Margarita Alcaraz, Iván Tellado,Natalia Cacabelos, Rocío Pego, Juan C. CarrilPharmacogenetics of Atremorine-InducedNeuroprotection and Dopamine Response inParkinsonʼs Disease

981 Caprioglio, Diego, Gianna Allegrone, Federica Pollastro,Stefano Valera, Annalisa Lopatriello, Juan A. Collado,Eduardo Munoz, Giovanni Appendino,Orazio Taglialatela-ScafatiO-Methyl Phytocannabinoids: Semi-synthesis, Analysisin Cannabis Flowerheads, and Biological Activity

670 Castejón, Maria Luisa, Maria Ángeles Rosillo,Isabel Villegas, Marina Sánchez-Hidalgo, Lila Hadidi,Farid Zaidi, Catalina Alarcón-de-la-LastraQuercus ilex Extract Ameliorates Acute TNBS-InducedColitis in Rats

738 Chen, Yanmin, Bujing Guo, Hongda Zhang, Lihong Hu,Jue WangHigenamine, a Dual Agonist for β1- and β2-AdrenergicReceptors Identified by Screening a Traditional ChineseMedicine Library

1008 Cherchar, Hanene, Immacolata Faraone,Massimiliano DʼAmbola, Chiara Sinisgalli, Fabrizio DalPiaz, Patrizia Oliva, Ahmed Kabouche, Zahia Kabouche,Luigi Milella, Antonio VassalloPhytochemistry and Antioxidant Activity of Aerial Partsof Phagnalon sordidum L.

1054 Damasceno, Carolina Sette, Natasha Tiemi FabriHigaki, Josiane de Dias, Marilis Dallarmi Miguel,Obdulio Gomes MiguelChemical Composition and Biological Activities ofEssential Oils in the Family Lauraceae: A SystematicReview of the Literature

957 de Amorim, Marcelo R., Felipe Hilário, Fernando M. dosSantos, João M. Batista, Tais M. Bauab, Angela R. Araújo,Iracilda Z. Carlos, Wagner Vilegas, Lourdes C. dos SantosNew Benzaldehyde and Benzopyran Compounds fromthe Endophytic Fungus Paraphaeosphaeria sp. F03 andTheir Antimicrobial and Cytotoxic Activities

203 de Freitas-Blanco, Veronica Santana,Karin Maia Monteiro, Patrícia Rosa de Oliveira,Ellen Cristina de Oliveira, Lucia Elaine de Oliveira Braga,João Ernesto de Carvalho, Rodney Alexandre FerreiraRodriguesSpilanthol, the Principal Alkylamide from Acmellaoleracea, Attenuates 5-Fluorouracil-Induced IntestinalMucositis in Mice

570 de Moura, Francyelle Borges, Allisson Benatti Justino,Bruno Antonio Ferreira, Foued Salmen Espindola,Fernanda de Araújo, Tatiana Carla TomiossoPro-Fibrogenic and Anti-Inflammatory Potential of aPolyphenol-Enriched Fraction from Annona crassiflorain Skin Repair

370 Dittharot, Kanthanadon, Sumana Dakeng,Parichat Suebsakwong, Apichart Suksamrarn,Pimpicha Patmasiriwat, Moltira PromkanCucurbitacin B Induces Hypermethylation of Oncogenesin Breast Cancer Cells

IV Contents

Planta Med 2019; 85

103 Dyrkheeva, Nadezhda, Olga Luzina,Aleksandr Filimonov, Olga Zakharova, Ekaterina Ilina,Alexandra Zakharenko, Maxim Kuprushkin,Dmitry Nilov, Irina Gushchina, Vytas Švedas,Nariman Salakhutdinov, Olga LavrikInhibitory Effect of New Semisynthetic Usnic AcidDerivatives on Human Tyrosyl-DNA Phosphodiesterase1

32 El-Elimat, Tamam, Karem H. Alzoubi,Mahmoud M. AbuAlSamen, Zeinab Y. Al Subeh,Tyler N. Graf, Nicholas H. OberliesSilymarin Prevents Memory Impairments, Anxiety,and Depressive-Like Symptoms in a Rat Model of Post-Traumatic Stress Disorder

1016 Elshamy, Abdelsamed Ibrahim,Heba Mohammed Abdallah, AbdEl-Nasser Gaber ElGendy, Walla El-Kashak, Beatrice Muscatello,Marinella De Leo, Luisa PistelliEvaluation of Anti-inflammatory, Antinociceptive, andAntipyretic Activities of Prunus persica var. nucipersica(Nectarine) Kernel

552 Esch, Stefan, Simone König, Bertan Bopp, Joachim Jose,Simone Brandt, Andreas HenselCryptotanshinone from Salvia miltiorrhizaRoots Reduces Cytokeratin CK1/10 Expression inKeratinocytes by Activation of Peptidyl-prolyl-cis-trans-isomerase FKBP1A

535 Espinosa-Leal, Claudia A., Silverio Garcia-LaraCurrent Methods for the Discovery of New ActiveIngredients from Natural Products for CosmeceuticalApplications

528 Esser, Philipp R., Sabine Mueller, Stefan F. MartinPlant Allergen-Induced Contact Dermatitis

987 Ezuruike, Udoamaka F., Elisabetta Chieli, Jose M. PrietoIn Vitro Modulation of Glibenclamide Transport byP-glycoprotein Inhibitory Antidiabetic African PlantExtracts

925 Faleschini, Maria Teresa, Anne Maier, Sarah Fankhauser,Katharina Thasis, Simon Hebeisen, Matthias Hamburger,Veronika ButterweckA FLIPR Assay for Discovery of GABAA ReceptorModulators of Natural Origin

745 Fürst, Robert, Betty Luong, Jörn Thomsen,Thomas WittigELOM-080 as Add-On Treatment for Respiratory TractDiseases – A Review of Clinical Studies Conducted inChina

591 Gaid, Mariam, Jendrik Füller, Christel Müller-GoymannThe Petroleum Ether Extract from Hypericumperforatum Root Cultures Exhibits PotentAntiproliferative Activity in Human Keratinocytes andFibroblasts

1044 Gauruder-Burmester, Annett, Stefan Heim, Brigitte Patz,Stephanie SeibtCucurbita pepo–Rhus aromatica–Humulus lupulusCombination Reduces Overactive Bladder Symptoms inWomen – A Noninterventional Study

412 Giacoman-Martínez, Abraham, Francisco J. Alarcón-Aguilar, Alejandro Zamilpa, Sergio Hidalgo-Figueroa,Gabriel Navarrete-Vázquez, Rebeca García-Macedo,Rubén Román-Ramos, Julio C. Almanza-PérezTriterpenoids from Hibiscus sabdariffa L. with PPARδ/γ Dual Agonist Action: In Vivo, In Vitro and In SilicoStudies

997 Gioti, Katerina, Anastasia Papachristodoulou,Dimitra Benaki, Sophia Havaki, Apostolos Beloukas,Argyro Vontzalidou, Nektarios Aligiannis, Alexios-Leandros Skaltsounis, Emmanuel Mikros, Roxane TentaSilymarin Enriched Extract (Silybum marianum)Additive Effect on Doxorubicin-Mediated Cytotoxicity inPC-3 Prostate Cancer Cells

14 Gómez-Verjan, Juan Carlos, Nadia Alejandra Rivero-Segura, Edgar Estrella-Parra, Ruth Rincón-Heredia,Abraham Madariaga-Mazón, Edgar Flores-Soto,Mario González-Meljem, Marco Cerbón, Ricardo Reyes-ChilpaNetwork Pharmacology Uncovers Anticancer Activityof Mammea-Type Coumarins from Calophyllumbrasiliense

1304 González-Cofrade, Laura, Beatriz de las Heras,Luis Apaza Ticona, Olga M. PalominoMolecular Targets Involved in the NeuroprotectionMediated by Terpenoids

1073 Goodman, Christopher Dean, An Thuy Hoang,Drissa Diallo, Karl Egil Malterud, Geoffrey I. McFadden,Helle WangensteenAnti-plasmodial Effects of Zanthoxylum zanthoxyloides

195 Grienke, Ulrike, Julia Zwirchmayr, Ursula Peintner,Ernst Urban, Martin Zehl, Michaela Schmidtke,Judith M. RollingerLanostane Triterpenes from Gloeophyllum odoratumand Their Anti-Influenza Effects

578 Guenther, Florian, Deborah Maus, Sarah Hedtrich,Matthias F. MelzigSerine Protease Mauritanicain from Euphorbiamauritanica and Phorbol-12-myristate-13-acetateModulate the IL-8 Release in Fibroblasts and HaCaTKeratinocytes

599 Ham, Baknoon, Myungsuk Kim, Yang-Ju Son,Sungyul Chang, SangHoon Jung, ChuWon Nho,ManJae KwonInhibitory Effects of Pterocarpus santalinus Extractagainst IgE/Antigen-Sensitized Mast Cells and AtopicDermatitis-Like Skin Lesions

678 Hu, Xiao-Long, Ya-Jun Niu, Mi Chen, Jia-Hao Feng,Wei Shen, Zhen-Zhou Jiang, Xiao-Qi Zhang, Wen-Cai Ye,Fei Xiong, Hao WangPreventive Effects of Total Flavonoid C-Glycosidesfrom Abrus mollis on Nonalcoholic Fatty Liver Diseasethrough Activating the PPARα Signaling Pathway

1128 Hwang, Youn-Hwan, Seon-A Jang, Taesoo Kim,Hyunil HaAnti-osteoporotic and Anti-adipogenic Effects of Rhuschinensis Nutgalls in Ovariectomized Mice Fed with aHigh-fat Diet

1034 Iannuzzi, Anna Maria, César Muñoz Camero,Massimiliano DʼAmbola, Valeria DʼAngelo, Smain Amira,Ammar Bader, Alessandra Braca, Nunziatina DeTommasi, Maria Paola GermanòAntiangiogenic Iridoids from Stachys ocymastrum andPremna resinosa

94 Jang, Hyun-Jae, Eun-Jae Park, Seung-Jae Lee, Hyung-Jin Lim, Jin Ha Jo, Seung Woong Lee, Mun-Chual RhoDiarylheptanoids from Curcuma phaeocaulis SuppressIL-6-Induced STAT3 Activation

465 Jeremic, Ivica, Sasa Petricevic, Vanja Tadic,Dragana Petrovic, Jelena Tosic, Zeljka Stanojevic,Milan Petronijevic, Sasenka Vidicevic,Vladimir Trajkovic, Aleksandra IsakovicEffects of Sideritis scardica Extract on GlucoseTolerance, Triglyceride Levels and Markers of OxidativeStress in Ovariectomized Rats

Contents V

Planta Med 2019; 85

112 Jiang, Meng-Yuan, Ming Luo, Kai Tian, Yan-Hong Li, Jing-Xian Sun, Ya Lu, Xiao-Yun Pu, Xiang-Zhong Huangα-Glucosidase Inhibitory and Anti-InflammatoryCoumestans from the Roots of Dolichos trilobus

583 Jo, Beom-Geun, No-June Park, Jonghwan Jegal,Sangho Choi, Sang Woo Lee, Li Wan Yi, Su-Nam Kim,Min Hye YangStellera chamaejasme and Its Main Compound Luteolin7-O-Glucoside Alleviates Skin Lesions in Oxazolone-and 2,4-Dinitrochlorobenzene-Stimulated MurineModels of Atopic Dermatitis

231 Joo, Hyejin, Jinhyun Bae, Jun-Seon Lee, Yumi Bang,Beom-Joon Lee, Jae-Woo Park, Kyungjin Lee, Jae-Heung Cho, Youngmin BuIcariin Improves Functional Behavior in a Mouse Modelof Traumatic Brain Injury and Promotes SynapticPlasticity Markers

453 Juvonen, Risto O., Filip Novák, Eleni Emmanouilidou,Seppo Auriola, Juri Timonen, Aki T. Heikkinen,Jenni Küblbeck, Moshe Finel, Hannu RaunioMetabolism of Scoparone in Experimental Animals andHumans

1024 Kerbab, Khawla, Francesca Sansone, Lahcene Zaiter,Tiziana Esposito, Rita Celano, Silvia Franceschelli,Michela Pecoraro, Fadila Benayache, Luca Rastrelli,Patrizia Picerno, Rita P. Aquino, Teresa MencheriniHalimium halimifolium: From the Chemical andFunctional Characterization to a NutraceuticalIngredient Design

766 Kim, Pansoo, Yeon-Ju Nam, Woo Jung Kim, Jin Kyu Kim,Gyeongbeen Lee, Myung-Jin Song, Jungeun Yang,Sun Shin Yi, Jong Suk Lee, Jin-Ho Seo, Yongmun ChoiEdgeworthia papyrifera Regulates Osteoblast andOsteoclast Differentiation In Vitro and Exhibits Anti-osteoporosis Activity in Animal Models of Osteoporosis

1233 Kirchinger, Michael, Lara Bieler, Julia Tevini,Michael Vogl, Elisabeth Haschke-Becher,Thomas K. Felder, Sebastien Couillard-Després,Herbert Riepl, Corinna UrmannDevelopment and Characterization of theNeuroregenerative Xanthohumol C/Hydroxypropyl-β-cyclodextrin Complex Suitable for ParenteralAdministration

1363 Ko, Yong-Hyun, Kyu-Yeon Shim, Seon-Kyung Kim,Jee-Yeon Seo, Bo-Ram Lee, Kwang-Hyun Hur, Young-Jung Kim, Seong-Eon Kim, Moon Ho Do, Amna Parveen,Sun Yeou Kim, Seok-Yong Lee, Choon-Gon JangLespedeza bicolor Extract Improves Amyloid Beta25 – 35-Induced Memory Impairments by UpregulatingBDNF and Activating Akt, ERK, and CREB Signaling inMice

755 Kumar, K.J. Senthil, M. Gokila Vani, Han-Wen Hsieh,Chin-Chung Lin, Sheng-Yang WangAntcin-A Modulates Epithelial-to-MesenchymalTransition and Inhibits Migratory and InvasivePotentials of Human Breast Cancer Cells via p53-Mediated miR-200c Activation

302 Lee, Hee-Weon, JinWook Kim, Joung-Han Yim, Hong-Kum Lee, Suhkneung PyoAnti-Inflammatory Activity of Lobaric Acid viaSuppressing NF-κB/MAPK Pathways or NLRP3Inflammasome Activation

719 Lee, Wonseok, Hye Ryoung Koo, You-Jin Choi,Jin Gyu Choi, Myung Sook Oh, Xing Jin, Munki Choo,Sunghyouk Park, Yoo-Seong Jeong, Suk-Jae Chung,Byung-Hoon LeeZ-ligustilide and n-Butylidenephthalide Isolated fromthe Aerial Parts of Angelica tenuissima Inhibit LipidAccumulation In Vitro and In Vivo

1242 Lee, Yun-Chae, Sung-Gook Cho, Sang-Woo Kim,Jeong Nam KimAnticariogenic Potential of Korean Native Plant Extractsagainst Streptococcus mutans

48 Lei, Yu, Peng Fu, Xie Jun, Peng ChengPharmacological Properties of Geraniol – A Review

563 Lei, Zhiyong, Zhijian Cao, Zaiwang Yang, Mingzhang Ao,Wenwen Jin, Longjiang YuRosehip Oil Promotes Excisional Wound Healing byAccelerating the Phenotypic Transition of Macrophages

708 Li, Tao, Jing-Jie Peng, E-Li Wang, Nian-Sheng Li, Feng-Lin Song, Jin-Fu Yang, Xiu-Ju Luo, Bin Liu, Jun PengMagnesium Lithospermate B Derived from Salviamiltiorrhiza Ameliorates Right Ventricle Remodelingin Pulmonary Hypertensive Rats via Inhibition of NOX/VPO1 Pathway

406 Lin, Chiu-Mei, Bao-Wei Wang, Wei-Jen Fang, Chun-Ming Pan, Kou-Gi Shyu, Sheng-Wen HouCatalpol Ameliorates Neointimal Hyperplasia inDiabetic Rats

1292 Martínez-Solís, Isabel, Nuria Acero, Francisco Bosch-Morell, Encarna Castillo, María Eugenia González-Rosende, Dolores Muñoz-Mingarro, Teresa Ortega,María Amparo Sanahuja, Victoria VillagrasaNeuroprotective Potential of Ginkgo biloba in RetinalDiseases

1150 Menke, Katrin, Melanie Schwermer,Alexander Schramm, Tycho J. ZuzakPreclinical Evaluation of Antitumoral and CytotoxicProperties of Viscum album Fraxini Extract on PediatricTumor Cells

1326 Moeini, Reihaneh, Zahra Memariani, Farideh Asadi,Mahbubeh Bozorgi, Narjes GorjiPistacia Genus as a Potential Source of NeuroprotectiveNatural Products

424 Mofidi Tabatabaei, Sahar, Samad Nejad Ebrahimi,Peyman Salehi, Ali Sonboli, Marzieh Tabefam,Marcel Kaiser, Matthias Hamburger, Mahdi MoridiFarimaniAntiprotozoal Germacranolide Sesquiterpene Lactonesfrom Tanacetum sonbolii

282 Moreira da Silva, Rodrigo, Cristiane Masetto deGaitani, Lucas Maciel Marques, Karina Fraige Baraco,Alberto José Cavalheiro, Luiz Alberto de Moraes,Norberto Peporine Lopes, Anderson Rodrigo de OliveiraCharacterization of Casearin X Metabolism by Rat andHuman Liver Microsomes

637 Nair, Jerald J., Johannes van StadenAntiplasmodial Lycorane Alkaloid Principles of the PlantFamily Amaryllidaceae

1316 Naushad, Mehjabeen, SivaSundaraKumar Durairajan,AmalKanti Bera, Sanjib Senapati, Min LiNatural Compounds with Anti-BACE1 Activity asPromising Therapeutic Drugs for Treating AlzheimerʼsDisease

1192 Oketch-Rabah, Hellen A., Robin J. Marles,Scott A. Jordan, Tieraona Low DogUnited States Pharmacopeia Safety Review of WillowBark

1216 Pacheco, SamantaDaliana Golin,Alexia Thamara Gasparin, CarlosHenrique Alves Jesus,Bruna Bittencourt Sotomaior, AnaClara Sans Ventura,DaianyDarlly Belo Redivo, Daniela de Cabrini,Josiane de Gaspari Dias, Marilis Dallarmi Miguel,Obdulio Gomes Miguel, Joice Maria da CunhaAntinociceptive and Anti-Inflammatory Effects of Bixin,a Carotenoid Extracted from the Seeds of Bixa orellana

VI Contents

Planta Med 2019; 85

41 Payon, Vilawan, Chanaporn Kongsaden,Wannarasmi Ketchart, Apiwat Mutirangura,Piyanuch WongananMechanism of Cepharanthine Cytotoxicity in HumanOvarian Cancer Cells

965 Pecio, Łukasz, Emad M. Hassan, Elsayed A. Omer,Gabriela Gajek, Renata Kontek, Andrzej Sobieraj,Anna Stochmal, Wiesław OleszekCytotoxic Cardenolides from the Leaves of Acokantheraoblongifolia

657 Pengzong, Zhang, Li Yuanmin, Xiong Xiaoming,Deng Shang, Xiong Wei, Lang Zhigang, Du Dongzhou,Yu Wenjing, Yue Jianbiao, Xiang Yang, Li XiaWound Healing Potential of the Standardized Extractof Boswellia serrata on Experimental Diabetic FootUlcer via Inhibition of Inflammatory, Angiogenetic andApoptotic Markers

1136 Prinsloo, Denise, Sandra van Dyk, Anél Petzer,Jacobus P. PetzerMonoamine Oxidase Inhibition by Kavalactones fromKava (Piper Methysticum)

1203 Razali, Nur Nadia, Chin Theng Ng, Lai Yen FongCardiovascular Protective Effects of Centella asiatica andIts Triterpenes: A Review

802 Ren, Yulin, A. Douglas KinghornNatural Product Triterpenoids and Their Semi-SyntheticDerivatives with Potential Anticancer Activity

825 Ríos, José-Luis, Isabel Andújar, Guillermo R. Schinella,Flavio FranciniModulation of Diabetes by Natural Products andMedicinal Plants via Incretins

869 Rosselli, Sergio, Gianfranco Fontana, Maurizio BrunoA Review of the Phytochemistry, Traditional Uses, andBiological Activities of the Genus Ballota and Otostegia

274 Salah El Dine, Riham, Hossam M. Abdallah,Zeinab A. Kandil, Ahmed A. Zaki, Shabana I. Khan,Ikhlas A. KhanPPARα and γ Activation Effects of New Nor-triterpenoidal Saponins from the Aerial Parts ofAnabasis articulata

856 Salomé Abarca, Luis Francisco, Peter G. Klinkhamer,Young Hae ChoiPlant Latex, from Ecological Interests to BioactiveChemical Resources

934 Sannella, Anna Rosa, Anastasia Karioti, Stefania Orsini,Aldo Scalone, Luigi Gradoni, Luigi Messori,Carlo Severini, Anna Rita BiliaLeaf Decoction of Carica papaya Combined withArtesunate Prevents Recrudescence in Plasmodiumberghei-Infected Mice

385 Santos, Stefanie, Christian Haslinger, Kristian Klaic,Maria T. Faleschini, Mónica Mennet, Olivier Potterat,Ursula von Mandach, Matthias Hamburger,Ana Paula Simões-WüstA Bufadienolide-Enriched Fraction of Bryophyllumpinnatum Inhibits Human Myometrial Contractility InVitro

619 Savi, Daiani Cristina, Rodrigo Aluizio, Chirlei GlienkeBrazilian Plants: An Unexplored Source of Endophytesas Producers of Active Metabolites

126 Scharf, Birte, Jandirk Sendker, Ulrich Dobrindt,Andreas HenselInfluence of Cranberry Extract on Tamm-HorsfallProtein in Human Urine and its Antiadhesive ActivityAgainst Uropathogenic Escherichia coli

524 Scheffler, ArminThe Wound Healing Properties of Betulin from BirchBark from Bench to Bedside

608 Seiwerth, Jasmin, Georgia Tasiopoulou, Julia Hoffmann,Ute Wölfle, Kay Schwabe, Karl-Werner Quirin,Christoph Mathis SchemppAnti-Inflammatory Effect of a Novel Topical HerbalComposition (VEL-091604) Consisting of Gentian Root,Licorice Root and Willow Bark Extract

1143 Shen, Zhanyun, Bo Zhu, Jiao Li, Luping QinRhein Augments Antiproliferative Effects ofAtezolizumab Based on Breast Cancer (4T1) Regression

1080 Shiokawa, Yayoi, Shino Miyauchi-Wakuda,Satomi Kagota, Kana Maruyama-Fumoto,Shizuo Yamada, Kazumasa ShinozukaAcanthopanax senticosus Induces Vasorelaxation viaEndothelial Nitric Oxide-Dependent and -IndependentPathways

210 Son, Hyo Jeong, Young Jin Jang, Chang Hwa Jung,Jiyun Ahn, Tae Youl Ha2,6-Dimethoxy-1,4-benzoquinone Inhibits 3T3-L1Adipocyte Differentiation via Regulation of AMPK andmTORC1

118 Stanisławska, Iwona J., Sebastian Granica,Jakub P. Piwowarski, Joanna Szawkało,Krzysztof Wiązecki, Zbigniew Czarnocki, Anna K. KissThe Activity of Urolithin A and M4 Valerolactone,Colonic Microbiota Metabolites of Polyphenols, in aProstate Cancer In Vitro Model

941 Stefanis, Ilias, Dimitra Hadjipavlou-Litina, Anna-Rita Bilia, Anastasia KariotiLC-MS- and NMR-Guided Isolation of MonoterpeneDimers from Cultivated Thymus vulgaris Varico 3Hybrid and Their Antityrosinase Activity

473 Sun, Si, Le Liu, Xiaojun Tian, Yanghongyun Guo,Yingkang Cao, Yunqing Mei, Changhua WangIcariin Attenuates High Glucose-Induced Apoptosis,Oxidative Stress, and Inflammation in Human UmbilicalVenous Endothelial Cells

24 Tóth, Barbara, Péter Hegyi, Tamás Lantos, Zsolt Szakács,Beáta Kerémi, Gábor Varga, Judit Tenk, Erika Pétervári,Márta Balaskó, Zoltán Rumbus, Zoltán Rakonczay,Emese Réka Bálint, Tivadar Kiss, Dezső CsuporThe Efficacy of Saffron in the Treatment of Mild toModerate Depression: A Meta-analysis

973 Vaccaro, Mariacarmela, Vivian Ocampo Bernal,Nicola Malafronte, Nunziatina De Tommasi,Antonietta LeoneHigh Yield of Bioactive Abietane Diterpenes in Salviasclarea Hairy Roots by Overexpressing CyanobacterialDXS or DXR Genes

335 Wang, An-dong, Chao-jie Xie, Yun-qiang Zhang, Mei-chen Li, Xia Wang, Jian-yu Liu, Yong-nan Xuα-Tetralonyl Glucosides from the Green Walnut Husksof Juglans mandshurica and Their AntiproliferativeEffects

225 Wang, Xinhui, Dujuan Wang, Xue Wang,Manana Khutsishvili, Kamilla Tamanyan,George Fayvush, Daniel Atha, Youcai Zhang,Robert P. BorrisIsoflavones from Camphorosma lessingii Inhibit theOrganic Anion Transporters OAT1 and OAT3

217 Woo, Sang-Uk, Hay-Ran Jang, Young-Won Chin,Hyungshin Yim7-O-Methylwogonin from Scutellaria baicalensisDisturbs Mitotic Progression by Inhibiting Plk1 Activityin Hep3B Cells

1374 Xi, Yu-Fei, Li-Li Lou, Zhi-Yong Xu, Zi-Lin Hou, Xiao-Bo Wang, Xiao-Xiao Huang, Shao-Jiang SongAlkaloid Enantiomers from Isatis tinctoria withNeuroprotective Effects against H2O2-Induced SH-SY5YCell Injury

Contents VII

Planta Med 2019; 85

394 Xing, Shao-Fang, Lin-Hua Liu, Ma-Li Zu, Man Lin, Xin-Fang Zhai, Xiang-Lan PiaoInhibitory Effect of Damulin B from Gynostemmapentaphyllum on Human Lung Cancer Cells

729 Yang, Bao, Hui Li, Qingfeng Ruan, Shenxin Xuan,Xiaojing Chen, Hui Cui, Zhongqiu Liu, Jing Jin,Zhongxiang ZhaoEffects of Gut Microbiota and Ingredient-IngredientInteraction on the Pharmacokinetic Properties ofRotundic Acid and Pedunculoside

692 Zhang, Bao-Bao, Xiao-Long Hu, Yu-Yan Wang, Jun-Yan Li, Thi-Anh Pham, Hao WangNeuroprotective Effects of Dammarane-Type Saponinsfrom Panax notoginseng on Glutamate-Induced CellDamage in PC12 Cells

444 Zhang, Bao-Jun, Wen-Wei Fu, Rong Wu, Jin-Ling Yang,Cai-Yun Yao, Bing-Xiong Yan, Hong-Sheng Tan, Chang-Wu Zheng, Zhi-Jun Song, Hong-Xi XuCytotoxic Prenylated Xanthones from the Leaves ofGarcinia bracteata

292 Zhang, Jianqiang, Qian Zhang, Yangrong Xu, Huixiang Li,Fenglan Zhao, Chaoming Wang, Zhi Liu, Pan Liu,Yanan Liu, Qingguo Meng, Feng ZhaoSynthesis and In Vitro Anti-inflammatory Activityof C20 Epimeric Ocotillol-Type Triterpenes andProtopanaxadiol

648 Zhao, Wen-Yu, Jing-Jie Chen, Chun-Xin Zou, Wei-Yu Zhou, Guo-Dong Yao, Xiao-Bo Wang, Bin Lin, Xiao-Xiao Huang, Shao-Jiang SongEffects of Enantiomerically Pure β-Carboline Alkaloidsfrom Picrasma quassioides on Human Hepatoma Cells

360 Zhu, Minyu, Jinwei Ying, Chaowei Lin, Yu Wang,Kelun Huang, Yang Zhou, Honglin TengBaicalin Induces Apoptotic Death of HumanChondrosarcoma Cells through MitochondrialDysfunction and Downregulation of the PI3K/Akt/mTORPathway

Editorial    

800 Braca, Alessandra, Nunziatina De TommasiEditorial

523 Hensel, AndreasEditorial

5 Kayser, Oliver, Robert FürstEditorial

93 Kayser, Oliver, Robert FürstEditorial

273 Kayser, Oliver, Robert FürstEditorial

1387 Stuppner, Hermann67th International Congress and Annual Meeting ofthe Society for Medicinal Plant and Natural ProductResearch (GA) in cooperation with the French Society ofPharmacognosy AFERP

I A Big Thank You to our Reviewers in the Past Year!1291 Editorial

Erratum    

e1 Wang, Mei, Amar G. Chittiboyina, Jon F. Parcher,Zulfiqar Ali, Paul Ford, Jianping Zhao, Bharathi Avula,Yan-Hong Wang, Ikhlas A. KhanErratum: Piper nigrum Oil – Determination of SelectedTerpenes for Quality Evaluation

e2 Zhang, Bao-Bao, Xiao-Long Hu, Yu-Yan Wang, Jun-Yan Li, Thi-Anh Pham, Hao WangErratum: Neuroprotective Effects of Dammarane-Type Saponins from Panax notoginseng on Glutamate-Induced Cell Damage in PC12 Cells

Formulation and Delivery Systems of Natural Products    

1114 Gerber, Werner, Dewald Steyn, Awie Kotzé,Hanna Svitina, Ché Weldon, Josias HammanCapsaicin and Piperine as Functional Excipients forImproved Drug Delivery across Nasal Epithelial Models

169 Mohtashami, Leila, Narjes Ghows, Zahra Tayarani-Najaran, Mehrdad IranshahiGalbanic Acid-Coated Fe3O4 Magnetic Nanoparticleswith Enhanced Cytotoxicity to Prostate Cancer Cells

258 Puglia, Carmelo, Debora Santonocito, Teresa Musumeci,Venera Cardile, Adriana Carol Graziano,Loredana Salerno, Giuseppina Raciti, Lucia Crascì,Anna Maria Panico, Giovanni PuglisiNanotechnological Approach to Increase theAntioxidant and Cytotoxic Efficacy of Crocin andCrocetin

Natural Product Chemistry and Analytical Studies    

503 Abdel-Wahab, Nada M., Sebastian Scharf,Ferhat C. Özkaya, Tibor Kurtán, Attila Mándi,Mostafa A. Fouad, Mohamed S. Kamel, Werner E. Müller,Rainer Kalscheuer, Wenhan Lin, Georgios Daletos,Weaam Ebrahim, Zhen Liu, Peter ProkschInduction of Secondary Metabolites from the Marine-Derived Fungus Aspergillus versicolor through Co-cultivation with Bacillus subtilis

145 Avula, Bharathi, Ji-Yeong Bae, Vijayasankar Raman,Omer I. Fantoukh, Yan-Hong Wang, Ahmed G. Osman,Mei Wang, Zulfiqar Ali, Ikhlas A. KhanQuantification of Phenolic Compounds from Fadogiaagrestis and Dietary Supplements using UHPLC-PDA-MS

1088 Basnet, Buddha Bahadur, Baosong Chen,Yerlan Melsuly Suleimen, Ke Ma, Shouyu Guo, Li Bao,Ying Huang, Hongwei LiuCytotoxic Secondary Metabolites from the EndolichenicFungus Hypoxylon fuscum

1160 Bittner, Marian, Regina Schenk, Andreas Springer,Matthias F. MelzigProfiles of Phenolic Acids and Triterpene Glycosides inCommercial and Cultivated Black Cohosh

1253 Cheesman, Matthew J., Alan White, Ben Matthews,Ian E. CockTerminalia ferdinandiana Fruit and Leaf Extracts InhibitMethicillin-Resistant Staphylococcus aureus Growth

496 Doan Thi Thuy, Ai, Van Trinh Thi Thanh,Huong Doan Thi Mai, HuyenTram Le, Marc Litaudon,VanHung Nguyen, VanMinh Chau, VanCuong PhamCytotoxic Alkaloids from Leaves of Pilea aff. martinii

917 Ge, Yanhui, Xiaojia Chen, Dejan Gođevac,Paula C. Bueno, Luis F. Salomé Abarca, Young Pyo Jang,Mei Wang, Young Hae ChoiMetabolic Profiling of Saponin-Rich Ophiopogonjaponicus Roots Based on 1H NMR and HPTLC Platforms

VIII Contents

Planta Med 2019; 85

431 Ibrahim, Elsayed A., Mei Wang, Mohamed M. Radwan,Amira S. Wanas, Chandrani G. Majumdar,Baharthi Avula, Yan-Hong Wang, Ikhlas A. Khan,Suman Chandra, Hemant Lata, Ghada M. Hadad,Randa A. Abdel Salam, Amany K. Ibrahim,Safwat A. Ahmed, Mahmoud A. ElSohlyAnalysis of Terpenes in Cannabis sativa L. Using GC/MS:Method Development, Validation, and Application

72 Jintao, Xue, Yang Quanwei, Li Chunyan, Jing Yun,Wang Shuangxi, Zhang Mingxiang, Li PengRapid and Simultaneous Determination of Three ActiveComponents in Raw and Processed Root Samples ofScutellaria baicalensis by Near-infrared Spectroscopy

81 Kai, Hisahiro, Yoshihiro Uesawa, Hisato Kunitake,Kazuhiro Morishita, Yoshihito Okada, Koji MatsunoDirect-Injection Electron Ionization-Mass SpectrometryMetabolomics Method for Analyzing BlueberryLeaf Metabolites That Inhibit Adult T-cell LeukemiaProliferation

1107 Kopp, Thomas, Mona Abdel-Tawab, Martin Khoeiklang,Boris MizaikoffDevelopment of a Selective Adsorbing Material forBinding of Pyrrolizidine Alkaloids in Herbal Extracts,Based on Molecular Group Imprinting

1177 Kruse, Lars H., Thomas Stegemann, Julia Jensen-Kroll, Annika Engelhardt, Anne-Maria Wesseling,Annemarie Lippert, Jutta Ludwig-Müller, Dietrich OberReduction of Pyrrolizidine Alkaloid Levels in Comfrey(Symphytum officinale) Hairy Roots by RNAi Silencingof Homospermidine Synthase

774 Lakornwong, Waranya, Kwanjai Kanokmedhakul,Kasem Soytong, Arm Unartngam, Sarawut Tontapha,Vittaya Amornkitbamrung, Somdej KanokmedhakulTypes A and D Trichothecene Mycotoxins from theFungus Myrothecium roridum

1263 Li, Wenyan, Zhongji Pu, Wenfang Yi, Qinge Ma,Qinhua Lin, Guoyue Zhong, Pengcheng Yao, Gang RenUnusual Prenylated Stilbene Derivatives with PTP1BInhibitory Activity from Artocarpus styracifolius

1098 Lu, Yan, Juan-Juan Zhang, Jiang-Yan Huo, Dao-Feng ChenStructural Characterization and Anti-complementaryActivities of Two Polysaccharides from Houttuyniacordata

781 Mudge, Elizabeth M., Paula N. Brown, Susan J. MurchThe Terroir of Cannabis: Terpene Metabolomics as aTool to Understand Cannabis sativa Selections

139 Parveen, Iffat, Natascha Techen, Ikhlas A. KhanIdentification of Species in the Aromatic Spice FamilyApiaceae Using DNA Mini-barcodes

911 Pompermaier, Luca, Stefan Schwaiger, Monizi Mawunu,Thea Lautenschlaeger, Hermann StuppnerDevelopment and Validation of a UHPLC-DAD Methodfor the Quantitative Analysis of Major DihydrochalconeGlucosides from Thonningia sanguinea VAHL

62 Rivera-Chávez, José, Tamam El-Elimat,Jacklyn M. Gallagher, Tyler N. Graf, Jacques Fournier,Gati K. Panigrahi, Gagan Deep, Rick L. Bunch,Huzefa A. Raja, Nicholas H. OberliesDelitpyrones: α-Pyrone Derivatives from a FreshwaterDelitschia sp.

513 Sama, Simko, Gerold Jerz, Mayank Thakur,Matthias F. Melzig, Alexander WengStructure-Activity Relationship of Transfection-Modulating Saponins – A Pursuit for the Optimal GeneTrafficker

154 Shi, Qiang-Qiang, Wei-Hua Wang, Jing Lu, Da-Shan Li,Lin Zhou, Ming-Hua QiuNew Cytotoxic Cycloartane Triterpenes from theAerial Parts of Actaea heracleifolia (syn. Cimicifugaheracleifolia)

185 Wang, Mei, Amar G. Chittiboyina, Jon F. Parcher,Zulfiqar Ali, Paul Ford, Jianping Zhao, Bharathi Avula,Yan-Hong Wang, Ikhlas A. KhanPiper nigrum Oil – Determination of Selected Terpenesfor Quality Evaluation

1168 Wang, Yingfang, Mengyuan Peng, Yanlin Chen,Wenjuan Wang, Zhihua He, Zemin Yang, Zhiyun Lin,Mengjuan Gong, Yongqin Yin, Yu ZengAnalysis of Panax ginseng miRNAs and Their TargetPrediction Based on High-Throughput Sequencing

160 Xu, Maonian, Starri Heidmarsson,Margret Thorsteinsdottir, Pawel Wasowicz, Hang Sun,Tao Deng, Sesselja Omarsdottir, Elin Soffia OlafsdottirInfraspecific Variation of Huperzine A and B in IcelandicHuperzia selago Complex

1275 Zhang, Ying-Ying, Xin-Yue Shang, Xue-Wen Hou, Ling-Zhi Li, Wei Wang, Toshihiko Hayashi, Yan Zhang, Guo-Dong Yao, Shao-Jiang SongYuanhuatine from Daphne genkwa selectively inducesmitochondrial apoptosis in estrogen receptor α-positivebreast cancer cells in vitro

Pharmacokinetic Investigations    

340 Avery, Bonnie A., Sai P. Boddu, Abhisheak Sharma,Edward B. Furr, Francisco Leon, Stephen J. Cutler,Christopher R. McCurdyComparative Pharmacokinetics of Mitragynine afterOral Administration of Mitragyna speciosa (Kratom)Leaf Extracts in Rats

56 Fan, Boyi, Baocheng Jiang, Sensen Yan, Bohui Xu,Huilian Huang, Guangtong ChenAnti-Inflammatory 18β-Glycyrrhetinin Acid DerivativesProduced by Biocatalysis

491 Manda, Vamshi K., Mona H. Haron, Tahir M. Mir,Bharathi Avula, Mohammad K. Ashfaq, Saqlain Haider,Amar G. Chittiboyina, Ikhlas A. Khan, Shabana I. KhanPharmacokinetics and Tissue Distribution of Aegelineafter Oral Administration in Mice

483 Songvut, Phanit, Pajaree Chariyavilaskul,Mayuree H. Tantisira, Phisit KhemawootSafety and Pharmacokinetics of Standardized Extractof Centella asiatica (ECa 233) Capsules in Healthy ThaiVolunteers: A Phase 1 Clinical Study

347 Teo, Yi Ling, Wei Fun Cheong, Amaury Cazenave-Gassiot, Shanshan Ji, Susan Logan, Zhi Xing Lee, Jun Li,Kok Yong Seng, Lawrence Soon-U Lee, Eu Leong YongPharmacokinetics of Prenylflavonoids following OralIngestion of Standardized Epimedium Extract inHumans

249 Zafar, Fatiqa, Nazish Jahan, Haq Nawaz BhattiIncreased Oral Bioavailability of Piperine from anOptimized Piper nigrum Nanosuspension

Authors' Index IX

Planta Med 2019; 85

    A

Abdallah, Heba Mohammed 1016Abdallah, Hossam M. 274Abdel Salam, Randa A. 431Abdel-Tawab, Mona 1107Abdel-Wahab, Nada M. 503Abrahams, Sameega 6AbuAlSamen, Mahmoud M. 32Acero, Nuria 1292Ahmed, Safwat A. 431Ahn, Jiyun 210Ahoua, Angora Rémi 379Alarcón-Aguilar, Francisco J. 412Alarcón-de-la-Lastra, Catalina 670Alcaraz, Margarita 1351Alejo, Ramón 1351Ali, Zulfiqar 145, 185, e1Aligiannis, Nektarios 997Allegrone, Gianna 981Almanza-Pérez, Julio C. 412Alqurashi, Yasir Mohammed 1225Al Subeh, Zeinab Y. 32Aluizio, Rodrigo 619Alzoubi, Karem H. 32Amira, Smain 1034Amornkitbamrung, Vittaya 774Andújar, Isabel 825Ao, Mingzhang 563Apaza Ticona, Luis 1304Appendino, Giovanni 981Aquino, Rita P. 1024Araújo, Angela R. 957Araújo, Fernanda de 570Asadi, Farideh 1326Ashafa, Anofi Omotayo 312Ashfaq, Mohammad K. 491Atha, Daniel 225Auriola, Seppo 453Autore, Giuseppina 947Avery, Bonnie A. 340Avula, Baharthi 431Avula, Bharathi 145, 185, 491, e1

    B

Bader, Ammar 1034Bae, Jinhyun 231Bae, Ji-Yeong 145Balaskó, Márta 24Bálint, Emese Réka 24Balogun, Fatai Oladunni 312Bang, Yumi 231Bao, Li 701, 1088Basnet, Buddha Bahadur 701, 1088Batista, João M. 957Bauab, Tais M. 957Beloukas, Apostolos 997Benaki, Dimitra 997Benayache, Fadila 1024Benny, Anju 239Benteldjoune, Mounira 947Bera, AmalKanti 1316Bhatti, Haq Nawaz 249Bieler, Lara 1233Bifulco, Giuseppe 947Bilia, Anna Rita 934Bilia, Anna-Rita 941

Bittner, Marian 1160Boddu, Sai P. 340Bonfoh, Bassirou 379Bopp, Bertan 552Borlat, Frédéric 379Borris, Robert P. 225Bosch-Morell, Francisco 1292Bottone, Alfredo 840Bouslama, Lamjed 1225Bozorgi, Mahbubeh 1326Braca, Alessandra 800, 1034Bramucci, Massimo 815Brandt, Simone 552Brown, Paula N. 781Bruno, Maurizio 815, 869Bu, Youngmin 231Bueno, Paula C. 917Bunch, Rick L. 62Butterweck, Veronika 925

    C

Cabrini, Daniela de 1216Cacabelos, Natalia 1351Cacabelos, Pablo 1351Cacabelos, Ramón 1351Camero, César Muñoz 1034Cao, Yingkang 473Cao, Zhijian 563Caprioglio, Diego 981Cardile, Venera 258Carlos, Iracilda Z. 957Carrera, Iván 1351Carril, Juan C. 1351Castejón, Maria Luisa 670Castillo, Encarna 1292Cavalheiro, Alberto José 282Cazenave-Gassiot, Amaury 347Celano, Rita 1024Cerbón, Marco 14Cerulli, Antonietta 840Chaieb, Kamel 1225Chandra, Suman 431Chang, Sungyul 599Chariyavilaskul, Pajaree 483Chau, VanMinh 496Cheesman, Matthew J. 1253Chen, Baosong 701, 1088Chen, Dao-Feng 1098Chen, Guangtong 56Chen, Jing-Jie 648Chen, Mi 678Chen, Xiaojia 917Chen, Xiaojing 729Chen, Yanlin 1168Chen, Yanmin 738Cheng, Peng 48Cheong, Wei Fun 347Cherchar, Hanene 1008Chieli, Elisabetta 987Chin, Young-Won 217Chini, Maria Giovanna 947Chittiboyina, Amar G. 185, 491, e1Cho, Jae-Heung 231Cho, Sung-Gook 1242Choi, Jin Gyu 719Choi, Sangho 583Choi, Yongmun 766

Choi, You-Jin 719Choi, Young Hae 856, 917Choo, Munki 719Christen, Philippe 379Chung, Suk-Jae 719Chunyan, Li 72Ciclet, Olivier 379Cock, Ian E. 1253Collado, Juan A. 981Corzo, Lola 1351Couillard-Després, Sebastien 1233Crascì, Lucia 258Csupor, Dezső 24Cuendet, Muriel 379Cui, Hui 729Cutler, Stephen J. 340Czarnocki, Zbigniew 118

    D

da Cunha, Joice Maria 1216Dakeng, Sumana 370Daletos, Georgios 503Dal Piaz, Fabrizio 1008Damasceno, Carolina Sette 1054de Amorim, Marcelo R. 957de Carvalho, João Ernesto 203Deep, Gagan 62de Freitas-Blanco, Veronica Santana 203de Gaitani, Cristiane Masetto 282de las Heras, Beatriz 1304De Leo, Marinella 1016de Moraes, Luiz Alberto 282de Moura, Francyelle Borges 570Deng, Tao 160de Oliveira, Anderson Rodrigo 282de Oliveira, Ellen Cristina 203de Oliveira, Patrícia Rosa 203de Oliveira Braga, Lucia Elaine 203De Tommasi, Nunziatina 800, 947, 973,1034Diallo, Drissa 1073Dias, Josiane de 1054Dittharot, Kanthanadon 370Do, Moon Ho 1363Doan Thi Mai, Huong 496Doan Thi Thuy, Ai 496Dobrindt, Ulrich 126Dongzhou, Du 657dos Santos, Fernando M. 957dos Santos, Lourdes C. 957Durairajan, SivaSundaraKumar 1316Dyrkheeva, Nadezhda 103DʼAmbola, Massimiliano 947, 1008,1034DʼAngelo, Valeria 1034DʼUrso, Gilda 840

    E

Ebrahim, Weaam 503El-Elimat, Tamam 32, 62El Gendy, AbdEl-Nasser Gaber 1016El-Kashak, Walla 1016Elshamy, Abdelsamed Ibrahim 1016ElSohly, Mahmoud A. 431Emmanouilidou, Eleni 453

X Authors' Index

Planta Med 2019; 85

Engelhardt, Annika 1177Esch, Stefan 552Espindola, Foued Salmen 570Espinosa-Leal, Claudia A. 535Esposito, Tiziana 1024Esser, Philipp R. 528Estrella-Parra, Edgar 14Ezuruike, Udoamaka F. 987

    F

Fabri Higaki, Natasha Tiemi 1054Faleschini, Maria T. 385, 925Fan, Boyi 56Fang, Wei-Jen 406Fankhauser, Sarah 925Fantoukh, Omer I. 145Faraone, Immacolata 1008Fayvush, George 225Felder, Thomas K. 1233Feng, Jia-Hao 678Fernández-Novoa, Lucía 1351Ferreira, Bruno Antonio 570Ferreira Rodrigues, Rodney Alexandre203Filimonov, Aleksandr 103Finel, Moshe 453Fiorini, Dennis 815Flores-Soto, Edgar 14Fong, Lai Yen 1203Fontana, Gianfranco 869Ford, Paul 185, e1Fouad, Mostafa A. 503Fournier, Jacques 62Fraige Baraco, Karina 282Franceschelli, Silvia 1024Francini, Flavio 825Fu, Peng 48Fu, Wen-Wei 444Füller, Jendrik 591Furr, Edward B. 340Fürst, Robert 5, 93, 273, 745

    G

Gaid, Mariam 591Gajek, Gabriela 965Gallagher, Jacklyn M. 62Garcia-Lara, Silverio 535García-Macedo, Rebeca 412Gaspari Dias, Josiane de 1216Gasparin, Alexia Thamara 1216Gauruder-Burmester, Annett 1044Ge, Yanhui 917Gelderblom, Wentzel 6Gerber, Werner 1114Germanò, Maria Paola 1034Ghows, Narjes 169Giacoman-Martínez, Abraham 412Gioti, Katerina 997Glienke, Chirlei 619Gómez-Verjan, Juan Carlos 14Gong, Mengjuan 1168González-Cofrade, Laura 1304González-Meljem, Mario 14González-Rosende, María Eugenia 1292Goodman, Christopher Dean 1073

Gorji, Narjes 1326Gođevac, Dejan 917Gradoni, Luigi 934Graf, Tyler N. 32, 62Granica, Sebastian 118Graziano, Adriana Carol 258Grienke, Ulrike 195Guenther, Florian 578Guo, Bujing 738Guo, Shouyu 701, 1088Guo, Yanghongyun 473Gushchina, Irina 103

    H

Ha, Hyunil 1128Ha, Tae Youl 210Hadad, Ghada M. 431Hadidi, Lila 670Hadjipavlou-Litina, Dimitra 941Haider, Saqlain 491Ham, Baknoon 599Hamburger, Matthias 385, 424, 925Hamman, Josias 1114Haron, Mona H. 491Haschke-Becher, Elisabeth 1233Haslinger, Christian 385Hassan, Emad M. 965Havaki, Sophia 997Hayashi, Toshihiko 1275He, Zhihua 1168Hebeisen, Simon 925Hedtrich, Sarah 578Hegyi, Péter 24Heidmarsson, Starri 160Heikkinen, Aki T. 453Heim, Stefan 1044Hensel, Andreas 126, 523, 552Hidalgo-Figueroa, Sergio 412Hilário, Felipe 957Hoang, An Thuy 1073Hoffmann, Julia 608Hou, Sheng-Wen 406Hou, Xue-Wen 1275Hou, Zi-Lin 1374Hsieh, Han-Wen 755Hu, Lihong 738Hu, Xiao-Long 678, 692, e2Huang, Huilian 56Huang, Kelun 360Huang, Xiang-Zhong 112Huang, Xiao-Xiao 648, 1374Huang, Ying 1088Huo, Jiang-Yan 1098Hur, Kwang-Hyun 1363Hwang, Youn-Hwan 1128

    I

Iannuzzi, Anna Maria 947, 1034Ibrahim, Amany K. 431Ibrahim, Elsayed A. 431Ilardi, Vincenzo 815Ilina, Ekaterina 103Iranshahi, Mehrdad 169Isakovic, Aleksandra 465

    J

Jahan, Nazish 249Jang, Choon-Gon 1363Jang, Hay-Ran 217Jang, Hyun-Jae 94Jang, Seon-A 1128Jang, Young Jin 210, 917Jegal, Jonghwan 583Jensen-Kroll, Julia 1177Jeong, Yoo-Seong 719Jeremic, Ivica 465Jerz, Gerold 513Jesus, CarlosHenrique Alves 1216Ji, Shanshan 347Jianbiao, Yue 657Jiang, Baocheng 56Jiang, Meng-Yuan 112Jiang, Zhen-Zhou 678Jin, Jing 729Jin, Wenwen 563Jin, Xing 719Jintao, Xue 72Jo, Beom-Geun 583Jo, Jin Ha 94Joo, Hyejin 231Jordan, Scott A. 1192Jose, Joachim 552Joubert, Elizabeth 6Jun, Xie 48Jung, Chang Hwa 210Jung, SangHoon 599Justino, Allisson Benatti 570Juvonen, Risto O. 453

    K

Kabouche, Ahmed 947, 1008Kabouche, Zahia 947, 1008Kagota, Satomi 1080Kai, Hisahiro 81Kaiser, Marcel 424Kalscheuer, Rainer 503Kamel, Mohamed S. 503Kandil, Zeinab A. 274Kanokmedhakul, Kwanjai 774Kanokmedhakul, Somdej 774Karioti, Anastasia 934, 941Kayser, Oliver 5, 93, 273Kerbab, Khawla 1024Kerémi, Beáta 24Ketchart, Wannarasmi 41Khan, Ikhlas A. 139, 145, 185, 274, 431,491, e1Khan, Shabana I. 274, 491Khemawoot, Phisit 483Khoeiklang, Martin 1107Khutsishvili, Manana 225Kim, Jeong Nam 1242Kim, Jin Kyu 766Kim, JinWook 302Kim, Myungsuk 599Kim, Pansoo 766Kim, Sang-Woo 1242Kim, Seong-Eon 1363Kim, Seon-Kyung 1363Kim, Sun Yeou 1363Kim, Su-Nam 583

Authors' Index XI

Planta Med 2019; 85

Kim, Taesoo 1128Kim, Woo Jung 766Kim, Young-Jung 1363Kinghorn, A. Douglas 802Kirchinger, Michael 1233Kiss, Anna K. 118Kiss, Tivadar 24Klaic, Kristian 385Klinkhamer, Peter G. 856Ko, Yong-Hyun 1363Koné, Mamidou Witabouna 379Kongsaden, Chanaporn 41König, Simone 552Kontek, Renata 965Koo, Hye Ryoung 719Kopp, Thomas 1107Kotzé, Awie 1114Kouidhi, Bochra 1225Kruse, Lars H. 1177Küblbeck, Jenni 453Kumar, K.J. Senthil 755Kunitake, Hisato 81Kuprushkin, Maxim 103Kurtán, Tibor 503Kwon, ManJae 599

    L

Lakornwong, Waranya 774Lantos, Tamás 24Lata, Hemant 431Lautenschlaeger, Thea 911Lavrik, Olga 103Le, HuyenTram 496Lee, Beom-Joon 231Lee, Bo-Ram 1363Lee, Byung-Hoon 719Lee, Gyeongbeen 766Lee, Hee-Weon 302Lee, Hong-Kum 302Lee, Jong Suk 766Lee, Jun-Seon 231Lee, Kyungjin 231Lee, Lawrence Soon-U 347Lee, Sang Woo 583Lee, Seok-Yong 1363Lee, Seung Woong 94Lee, Seung-Jae 94Lee, Wonseok 719Lee, Yun-Chae 1242Lee, Zhi Xing 347Lei, Yu 48Lei, Zhiyong 563Leon, Francisco 340Leone, Antonietta 973Li, Da-Shan 154Li, Hui 729Li, Huixiang 292Li, Jiao 1143Li, Jun 347Li, Jun-Yan 692, e2Li, Ling-Zhi 1275Li, Mei-chen 335Li, Min 1316Li, Nian-Sheng 708Li, Tao 708Li, Wenyan 1263Li, Yan-Hong 112

Lilly, Mariska 6Lim, Hyung-Jin 94Lin, Bin 648Lin, Chaowei 360Lin, Chin-Chung 755Lin, Chiu-Mei 406Lin, Man 394Lin, Qinhua 1263Lin, Wenhan 503Lin, Zhiyun 1168Lippert, Annemarie 1177Litaudon, Marc 496Liu, Bin 708Liu, Hongwei 701, 1088Liu, Jian-yu 335Liu, Le 473Liu, Li 701Liu, Lin-Hua 394Liu, Pan 292Liu, Yanan 292Liu, Zhen 503Liu, Zhi 292Liu, Zhongqiu 729Logan, Susan 347Lopatriello, Annalisa 981Lopes, Norberto Peporine 282Lou, Li-Li 1374Low Dog, Tieraona 1192Lu, Jing 154Lu, Ya 112Lu, Yan 1098Ludwig-Müller, Jutta 1177Luo, Ming 112Luo, Xiu-Ju 708Luong, Betty 745Lupidi, Giulio 815Luzina, Olga 103

    M

Ma, Ke 1088Ma, Qinge 1263Madariaga-Mazón, Abraham 14Maggi, Filippo 815Maier, Anne 925Majumdar, Chandrani G. 431Malafronte, Nicola 973Malterud, Karl Egil 1073Manda, Vamshi K. 491Mándi, Attila 503Marcourt, Laurence 379Marles, Robin J. 1192Marques, Lucas Maciel 282Martin, Stefan F. 528Martínez-Solís, Isabel 1292Maruyama-Fumoto, Kana 1080Marzocco, Stefania 947Masullo, Milena 840Matsuno, Koji 81Matthews, Ben 1253Maus, Deborah 578Mawunu, Monizi 911McCurdy, Christopher R. 340McFadden, Geoffrey I. 1073Mei, Yunqing 473Melzig, Matthias F. 513, 578, 1160Memariani, Zahra 1326Mencherini, Teresa 1024

Meng, Qingguo 292Menke, Katrin 1150Mennet, Mónica 385Messori, Luigi 934Miguel, Marilis Dallarmi 1054, 1216Miguel, Obdulio Gomes 1054, 1216Mikros, Emmanuel 997Milella, Luigi 1008Mingxiang, Zhang 72Mir, Tahir M. 491Miyauchi-Wakuda, Shino 1080Mizaikoff, Boris 1107Moeini, Reihaneh 1326Mofidi Tabatabaei, Sahar 424Mohtashami, Leila 169Monteillier, Aymeric 379Monteiro, Karin Maia 203Montoro, Paola 840Moreira da Silva, Rodrigo 282Moridi Farimani, Mahdi 424Morishita, Kazuhiro 81Mudge, Elizabeth M. 781Mueller, Sabine 528Müller, Werner E. 503Müller-Goymann, Christel 591Munoz, Eduardo 981Muñoz-Mingarro, Dolores 1292Murch, Susan J. 781Muscatello, Beatrice 1016Musumeci, Teresa 258Mutirangura, Apiwat 41

    N

Nair, Jerald J. 637Nam, Yeon-Ju 766Napolitano, Assunta 840Naushad, Mehjabeen 1316Navarrete-Vázquez, Gabriel 412Nejad Ebrahimi, Samad 379, 424Ng, Chin Theng 1203Nguyen, VanHung 496Nho, ChuWon 599Nilov, Dmitry 103Niu, Ya-Jun 678Novák, Filip 453

    O

Ober, Dietrich 1177Oberlies, Nicholas H. 32, 62Ocampo Bernal, Vivian 973Oh, Myung Sook 719Okada, Yoshihito 81Oketch-Rabah, Hellen A. 1192Olafsdottir, Elin Soffia 160Oleszek, Wiesław 965Oliva, Patrizia 1008Omarsdottir, Sesselja 160Omer, Elsayed A. 965Orsini, Stefania 934Ortega, Teresa 1292Osman, Ahmed G. 145Özkaya, Ferhat C. 503

XII Authors' Index

Planta Med 2019; 85

    P

Pacheco, SamantaDaliana Golin 1216Palomino, Olga M. 1304Pan, Chun-Ming 406Panico, Anna Maria 258Panigrahi, Gati K. 62Papachristodoulou, Anastasia 997Papetti, Adele 1225Parcher, Jon F. 185, e1Park, Eun-Jae 94Park, Jae-Woo 231Park, No-June 583Park, Sunghyouk 719Parveen, Amna 1363Parveen, Iffat 139Patmasiriwat, Pimpicha 370Patz, Brigitte 1044Payon, Vilawan 41Pecio, Łukasz 965Pecoraro, Michela 1024Pego, Rocío 1351Peintner, Ursula 195Peng, Jing-Jie 708Peng, Jun 708Peng, Li 72Peng, Mengyuan 1168Pengzong, Zhang 657Pétervári, Erika 24Petricevic, Sasa 465Petronijevic, Milan 465Petrovic, Dragana 465Petzer, Anél 1136Petzer, Jacobus P. 1136Pham, Thi-Anh 692, e2Pham, VanCuong 496Piacente, Sonia 840Piao, Xiang-Lan 394Picerno, Patrizia 1024Pistelli, Luisa 1016Piwowarski, Jakub P. 118Pollastro, Federica 981Pompermaier, Luca 911Potterat, Olivier 385Prieto, Jose M. 987Prinsloo, Denise 1136Proksch, Peter 503Promkan, Moltira 370Pu, Xiao-Yun 112Pu, Zhongji 1263Puglia, Carmelo 258Puglisi, Giovanni 258Pyo, Suhkneung 302

    Q

Qin, Luping 1143Qiu, Ming-Hua 154Quanwei, Yang 72Quassinti, Luana 815Quirin, Karl-Werner 608

    R

Raciti, Giuseppina 258Radwan, Mohamed M. 431Raja, Huzefa A. 62

Rakonczay, Zoltán 24Raman, Vijayasankar 145Rastrelli, Luca 1024Raunio, Hannu 453Razali, Nur Nadia 1203Redivo, DaianyDarlly Belo 1216Ren, Gang 1263Ren, Jinwei 701Ren, Yulin 802Reyes-Chilpa, Ricardo 14Rho, Mun-Chual 94Riepl, Herbert 1233Rincón-Heredia, Ruth 14Ríos, José-Luis 825Rivera-Chávez, José 62Rivero-Segura, Nadia Alejandra 14Rodríguez, Susana 1351Rollinger, Judith M. 195Román-Ramos, Rubén 412Rosillo, Maria Ángeles 670Rosselli, Sergio 869Ruan, Qingfeng 729Rumbus, Zoltán 24

    S

Salah El Dine, Riham 274Salakhutdinov, Nariman 103Salehi, Peyman 424Salerno, Loredana 258Salomé Abarca, Luis F. 856, 917Sama, Simko 513Samodien, Sedicka 6Sanahuja, María Amparo 1292Sánchez-Hidalgo, Marina 670Sannella, Anna Rosa 934Sansone, Francesca 1024Santonocito, Debora 258Santos, Stefanie 385Savi, Daiani Cristina 619Scalone, Aldo 934Scharf, Birte 126Scharf, Sebastian 503Scheffler, Armin 524Schempp, Christoph Mathis 608Schenk, Regina 1160Schinella, Guillermo R. 825Schmidtke, Michaela 195Schramm, Alexander 1150Schwabe, Kay 608Schwaiger, Stefan 911Schwermer, Melanie 1150Seibt, Stephanie 1044Seiwerth, Jasmin 608Senapati, Sanjib 1316Sendker, Jandirk 126Seng, Kok Yong 347Seo, Jee-Yeon 1363Seo, Jin-Ho 766Severini, Carlo 934Shang, Deng 657Shang, Xin-Yue 1275Sharma, Abhisheak 340Shen, Wei 678Shen, Zhanyun 1143Shi, Qiang-Qiang 154Shim, Kyu-Yeon 1363Shinozuka, Kazumasa 1080

Shiokawa, Yayoi 1080Shuangxi, Wang 72Shyu, Kou-Gi 406Simões-Wüst, Ana Paula 385Sinisgalli, Chiara 1008Skaltsounis, Alexios-Leandros 997Sobieraj, Andrzej 965Son, Hyo Jeong 210Son, Yang-Ju 599Sonboli, Ali 424Song, Feng-Lin 708Song, Myung-Jin 766Song, Shao-Jiang 648, 1275, 1374Song, Zhi-Jun 444Songvut, Phanit 483Sotomaior, Bruna Bittencourt 1216Soytong, Kasem 774Springer, Andreas 1160Stanisławska, Iwona J. 118Stanojevic, Zeljka 465Stefanis, Ilias 941Stegemann, Thomas 1177Steyn, Dewald 1114Stochmal, Anna 965Stuppner, Hermann 911, 1387Suebsakwong, Parichat 370Suksamrarn, Apichart 370Suleimen, Yerlan Melsuly 701, 1088Sun, Hang 160Sun, Jing-Xian 112Sun, Si 473Švedas, Vytas 103Svitina, Hanna 1114Szakács, Zsolt 24Szawkało, Joanna 118

    T

Tabefam, Marzieh 424Tadic, Vanja 465Taglialatela-Scafati, Orazio 981Tamanyan, Kamilla 225Tan, Hong-Sheng 444Tantisira, Mayuree H. 483Tasiopoulou, Georgia 608Tayarani-Najaran, Zahra 169Techen, Natascha 139Tellado, Iván 1351Teng, Honglin 360Tenk, Judit 24Tenta, Roxane 997Teo, Yi Ling 347Tevini, Julia 1233Thakur, Mayank 513Thasis, Katharina 925Thomas, Jaya 239Thomsen, Jörn 745Thorsteinsdottir, Margret 160Tian, Kai 112Tian, Xiaojun 473Timonen, Juri 453Tomiosso, Tatiana Carla 570Tontapha, Sarawut 774Tosic, Jelena 465Tóth, Barbara 24Trajkovic, Vladimir 465Trinh Thi Thanh, Van 496

Authors' Index XIII

Planta Med 2019; 85

    U

Uesawa, Yoshihiro 81Unartngam, Arm 774Urban, Ernst 195Urmann, Corinna 1233

    V

Vaccaro, Mariacarmela 973Valera, Stefano 981van Dyk, Sandra 1136Vani, M. Gokila 755van Staden, Johannes 637Varga, Gábor 24Vassallo, Antonio 1008Venditti, Alessandro 815Ventura, AnaClara Sans 1216Vidicevic, Sasenka 465Vilegas, Wagner 957Villagrasa, Victoria 1292Villegas, Isabel 670Vogl, Michael 1233von Mandach, Ursula 385Vontzalidou, Argyro 997

    W

Wanas, Amira S. 431Wang, An-dong 335Wang, Bao-Wei 406Wang, Changhua 473Wang, Chaoming 292Wang, Dujuan 225Wang, E-Li 708Wang, Hao 678, 692, e2Wang, Jue 738Wang, Mei 145, 185, 431, 917, e1Wang, Sheng-Yang 755Wang, Wei 1275Wang, Wei-Hua 154Wang, Wenjuan 1168Wang, Xia 335Wang, Xiao-Bo 648, 1374Wang, Xinhui 225Wang, Xue 225Wang, Yan-Hong 145, 185, 431, e1Wang, Yingfang 1168Wang, Yu 360Wang, Yu-Yan 692, e2Wangensteen, Helle 1073Wasowicz, Pawel 160Wei, Xiong 657Weldon, Ché 1114Weng, Alexander 513Wenjing, Yu 657Wesseling, Anne-Maria 1177White, Alan 1253Wiązecki, Krzysztof 118Wittig, Thomas 745Wölfle, Ute 608Wonganan, Piyanuch 41Woo, Sang-Uk 217Wu, Rong 444

    X

Xi, Yu-Fei 1374Xia, Li 657Xiaoming, Xiong 657Xie, Chao-jie 335Xing, Shao-Fang 394Xiong, Fei 678Xu, Bohui 56Xu, Hong-Xi 444Xu, Maonian 160Xu, Yangrong 292Xu, Yong-nan 335Xu, Zhi-Yong 1374Xuan, Shenxin 729

    Y

Yamada, Shizuo 1080Yan, Bing-Xiong 444Yan, Sensen 56Yang, Bao 729Yang, Jin-Fu 708Yang, Jin-Ling 444Yang, Jungeun 766Yang, Min Hye 583Yang, Xiang 657Yang, Zaiwang 563Yang, Zemin 1168Yao, Cai-Yun 444Yao, Guo-Dong 648, 1275Yao, Pengcheng 1263Ye, Wen-Cai 678Yi, Li Wan 583Yi, Sun Shin 766Yi, Wenfang 1263Yim, Hyungshin 217Yim, Joung-Han 302Yin, Yongqin 1168Ying, Jinwei 360Yong, Eu Leong 347Yu, Haiyang 701Yu, Longjiang 563Yuanmin, Li 657Yun, Jing 72

    Z

Zafar, Fatiqa 249Zaidi, Farid 670Zaiter, Lahcene 1024Zakharenko, Alexandra 103Zakharova, Olga 103Zaki, Ahmed A. 274Zamilpa, Alejandro 412Zehl, Martin 195Zeng, Yu 1168Zhai, Xin-Fang 394Zhang, Bao-Bao 692, e2Zhang, Bao-Jun 444Zhang, Hongda 738Zhang, Jianqiang 292Zhang, Juan-Juan 1098Zhang, Qian 292Zhang, Xiao-Qi 678Zhang, Yan 1275Zhang, Ying-Ying 1275

Zhang, Youcai 225Zhang, Yun-qiang 335Zhao, Feng 292Zhao, Fenglan 292Zhao, Jianping 185, e1Zhao, Wen-Yu 648Zhao, Zhongxiang 729Zheng, Chang-Wu 444Zhigang, Lang 657Zhong, Guoyue 1263Zhou, Lin 154Zhou, Wei-Yu 648Zhou, Yang 360Zhu, Bo 1143Zhu, Minyu 360Zou, Chun-Xin 648Zu, Ma-Li 394Zuzak, Tycho J. 1150Zwirchmayr, Julia 195