economics of one health
TRANSCRIPT
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Economics of One Health
Delia Grace, Bernard Bett, Karl Rich, Francis Wanyoike, Johanna Lindahl and Tom Randolph
One Health for the Real World: Zoonoses, Ecosystems and Wellbeing, 17–18 March 2016
Dynamic Drivers of Disease in Africa ConsortiumNE-J001570-1
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Burdens of zoonoses
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The challenge of defining zoonotic burden
DDDAC Lindahl et al., submitted
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The challenge of multiple burdens
Burden of illness in
people (DALY’s)
Costs of treating
disease in people ($)
Losses in agri-food chains
($)
Costs of Responding to
disease in food chains($)
Costs of preventing disease in
people
Costs of preventing disease in food chain
Direct impact
Treatment Prevention
People
Animals
Losses due to ecosystem
impacts(?)
Ecosystem
DDDAC Shaw & Grace, 2014
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The challenge of misdiagnosis
DDDAC Bett, project results
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Bovine brucellosis official reports 2008-2012
Bovine brucellosis according to 440 surveys
Source: LRI report to DFID Mapping poverty and likely zoonosis hotspots
The challenge of under-reporting
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Burden of zoonotic disease
HIV Malaria All FBD Zoonotic FBD NTD Zoonotic NTD0
10,000,000
20,000,000
30,000,000
40,000,000
50,000,000
60,000,000
70,000,000
80,000,000
90,000,000
DALYs
Source: adapted from IMHE and WHO FERG report
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Zoonoses make up 75% of EIDs and cost 6.7 billion a year
Burden of emerging infectious disease
Source: LRI report to DFID Mapping poverty and likely zoonosis hotspots
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Reliable benefits from controlling endemic zoonoses
Credible economic cost benefit studies on brucellosis control (n=13)– Average benefit cost ratio 6:1– Median 4:1– Range 1.1-19.8
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Ex ante 5Ex post 6.6
Developing countries 3.7Developed countries 7.4
DDDAC Grace, 2015
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Burden (DALYs)
Foodborne zoonoses
Neglected tropical zoonoses
Emerging zoonoses
Priority of state veterinary services in Africa
Foodborne zoonoses
Neglected tropical zoonoses
Emerging Zoonoses
Source: Grace et al., 2015
Source: IMHE and WHO FERG report
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Drivers of wellbeing outcomes
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Source: Randolph 2011
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Source: Gillespie et al, 2012; Masset et al, 2012; Webb, 2013
Zoonoses
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DDDAC Framework
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System dynamics model
Interventions
Outcomes
Policy and implementation
recommendations
Economic costs
Animal disease
Market performance
Herd dynamics
Vector transmission
DDDAC Rich et al., in progress
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Effect of vaccination delay on cattle pop.
12:23 PM Thu, Oct 23, 2014
Untitled
Page 11.00 183.25 365.50 547.75 730.00
Day s
1:
1:
1:
3150
3550
3950
Total animals: 1 - 2 - 3 - 4 - 5 -
1
1
1
1
2
2
2
2
3
3
3
3
4
4
4
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5
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4 wk delay
I wk delay
No vax
Immediate vax
DDDAC Wanyoike et al. project results
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From drivers to decisions
Interventions
Outcomes
Policy and implementation
recommendations
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Annual benefit Annual cost Confidence in investment
Sharing resources 4 billion 1 billion ++
Controllable zoonoses
85 billion 21 billion +++
Timely response 6 billion
3.4 billion
++
Averting pandemics
30 billion +
Generating insights
? ? +++
Bottom line 125 billion 25 billion +++
Building a business case for zoonoses control
DDDAC Grace, 2015
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Conclusions
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Zoonoses & poverty Poor people get exposed to zoonoses (DDDAC, Dzingirai et al., submitted)
– Ecosystem modification, gender, occupation can affect risk– But statistical relation between poverty and zoonoses often weak and relations
between ecosystem and disease outcomes complex (DDDAC, Muriuki, 2015)
Good evidence for high levels of multiple zoonotic infections – But high levels of under-reporting and misdiagnosis– And less data for specific health and livelihood outcomes related to this
Expenditure on human and animal health prevention and cure a significant burden for poor people– But less evidence on the role of zoonoses in this or benefit for zoonosis control
Official and public response to outbreak diseases impose a large part of the burden
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• In developing countries, human sickness is a major cause of falling into and remaining in poverty
• Zoonoses are responsible for a substantial proportion of human illnesses in developing countries
• Lack of agreed definitions and metrics hinders understanding of the impact of zoonoses on human health
• Participatory and expert prioritisations of zoonoses are often misleading• Little information on multiple infections
• Neglected, endemic zoonoses have more important poverty impacts than emerging diseases
• Responses to zoonoses are often anti-poor, and may be more injurious than zoonoses themselves
Conclusions
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Funded by the ESPA programme which is funded by the Department for International Development (DFID), the Economic and Social Research Council (ESRC) and the Natural Environment Research Council (NERC)
With additional Support from the CGIAR Research Program on Agriculture for Nutrition and Health is led by the International Food Policy Research Institute, Washington