duke urology update...oct 13, 2012  · new imaging technology to perform partial nephrectomy for...

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I t has been a busy summer in Durham with the opening of the new Duke Medicine Pavilion in July. This major expansion of Duke Uni- versity Hospital includes 16 operating suites and 160 critical care beds that greatly expands our ability to provide enhanced care for our patients. We, also, welcomed two new faculty members: Dr. Chuck Scales, who recently finished a Robert Wood Johnson Foundation Clinical Scholars Fellowship in Health Sciences Research at UCLA and Dr. Sam Eaton, who recently completed an Endo-urology fellowship at Northwest- ern University. We had an extremely impressive showing at this year’s AUA meeting in San Diego. In fact, our Duke Urology alumni reception held on Satur- day evening May 4, 2013 broke all attendance records. It was wonderful to see all of our DYSURICs and friends from across the country and around the world. We anticipate an equally impressive showing at the upcoming AUA meeting in Orlando in 2014. This past June, we graduated three outstanding chief residents, John Mancini, Suzanne Stewart and Brian Whitley. I had the opportunity to see all three at Brian’s wedding in Durham. John, Suzanne and Brian all appear to be enjoying their current positions. We are extremely proud of these individuals and know that they will stay in contact with the program. We are especially proud of our residents who have achieved major accomplishments over the past few months. Tara Ortiz received a Urology Care Foundation 2013 Residency Research Award at the AUA meeting in San Diego and Zarine Balsara represented Duke Urology on the Southeastern Section team that won the Annual Residency Bowl during the AUA. There were also major accomplishments for our faculty. Brant Inman was named the Cary Robertson Assistant Professor of Urology in June. In addition, John Wiener was named to the American Board of Urology Examination Com- mittee to write the questions for the Urology Board Exams, annual resi- dent in-service exams, the SASP program, and Pediatric Urology Certification Examination. Our newsletter includes updates on our progress here at Duke and in our Duke Urology of Raleigh practice. In addition, Sherry Ross provides a wonderful update of our Pediatric Urology Research Program. Finally, John Wiener provides an update on Duke Urology CME activities. We are especially excited about our upcoming 46th annual Duke Urologic As- sembly symposium, which will be held in Pinehurst in early April, 2014. We would love to see as many DYSURIC’s as possible attending this meet- ing, as we will have a special dinner for our DYSURIA members. I believe that our alumni are our most loyal supporters. We value your ideas, feedback and contri- butions. With industry funding virtually at a standstill, it is becoming much more difficult to support the educational activities of our residency program. Never has it been more critical that we receive sup- port from our alumni for the continued success of Duke Urology. I would urge you to consider making a contribution to the DYSURIA society, which will go 100% to help support urology resident training at Duke. As we strive to keep our program as one of the elite training programs in the country, your support of resident education becomes even more critical. Please consider making a year-end gift to DYSURIA. As always, we welcome you back to Durham for a visit so we can show you how much we have grown both within Duke Urology and at the Duke University Medical Center. All the best for a wonderful holiday season, Glenn DUKE UROLOGY A Division of the Department of Surgery INSIDE: Faculty News ...... 2 New Faculty ........ 3 Faculty Awards ... 3 Clinical Section ... 4 Resident Section . 5 Research Section. 7 Recent Significant Papers ................ 8 Alumni Section .... 10 Continuing Medical Education Section ............... 11 Duke Urologic Assembly Symposium ......... 12 DUKE UROLOGY UPDATE Fall 2013 We are especially excited about our upcoming 46th annual Duke Urologic Assembly symposium, which will be held in Pinehurst in early April, 2014.Glenn M. Preminger, MD Chief of the Division of Urology WELCOME

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Page 1: DUKE UROLOGY UPDATE...Oct 13, 2012  · new imaging technology to perform partial nephrectomy for kidney cancer patients. The new imaging technology trademarked FireFly ®, by Intuitive

It has been a busy summer in Durham with the opening of the newDuke Medicine Pavilion in July. This major expansion of Duke Uni-versity Hospital includes 16 operating suites and 160 critical care

beds that greatly expands our ability to provide enhanced care for ourpatients. We, also, welcomed two new faculty members: Dr. ChuckScales, who recently finished a Robert Wood Johnson Foundation ClinicalScholars Fellowship in Health Sciences Research at UCLA and Dr. SamEaton, who recently completed an Endo-urology fellowship at Northwest-ern University.

We had an extremely impressive showing at this year’s AUA meetingin San Diego. In fact, our Duke Urology alumni reception held on Satur-day evening May 4, 2013 broke all attendance records. It was wonderfulto see all of our DYSURICs and friends from across the country andaround the world. We anticipate an equally impressive showing at theupcoming AUA meeting in Orlando in 2014.

This past June, we graduated three outstanding chief residents, John Mancini, Suzanne Stewartand Brian Whitley. I had the opportunity to see all three at Brian’s wedding in Durham. John, Suzanneand Brian all appear to be enjoying their current positions. We are extremely proud of these individualsand know that they will stay in contact with the program.

We are especially proud of our residents who have achieved major accomplishments over the pastfew months. Tara Ortiz received a Urology Care Foundation 2013 Residency Research Award at the AUAmeeting in San Diego and Zarine Balsara represented Duke Urology on the Southeastern Section teamthat won the Annual Residency Bowl during the AUA. There were alsomajor accomplishments for our faculty. Brant Inman was named the CaryRobertson Assistant Professor of Urology in June. In addition, JohnWiener was named to the American Board of Urology Examination Com-mittee to write the questions for the Urology Board Exams, annual resi-dent in-service exams, the SASP program, and Pediatric UrologyCertification Examination.

Our newsletter includes updates on our progress here at Duke andin our Duke Urology of Raleigh practice. In addition, Sherry Ross providesa wonderful update of our Pediatric Urology Research Program. Finally,John Wiener provides an update on Duke Urology CME activities. We areespecially excited about our upcoming 46th annual Duke Urologic As-sembly symposium, which will be held in Pinehurst in early April, 2014.We would love to see as many DYSURIC’s as possible attending this meet-ing, as we will have a special dinner for our DYSURIA members.

I believe that our alumni are our most loyal supporters. We value your ideas, feedback and contri-butions. With industry funding virtually at a standstill, it is becoming much more difficult to supportthe educational activities of our residency program. Never has it been more critical that we receive sup-port from our alumni for the continued success of Duke Urology. I would urge you to consider makinga contribution to the DYSURIA society, which will go 100% to help support urology resident training atDuke. As we strive to keep our program as one of the elite training programs in the country, your supportof resident education becomes even more critical.

Please consider making a year-end gift to DYSURIA. As always, we welcome you back to Durhamfor a visit so we can show you how much we have grown both within Duke Urology and at the DukeUniversity Medical Center.

All the best for a wonderful holiday season,Glenn

DUKEUROLOGY

A Divisionof the Department of Surgery

INSIDE:

Faculty News ...... 2

New Faculty........ 3

Faculty Awards ... 3

Clinical Section ... 4

Resident Section . 5

Research Section . 7

Recent Significant

Papers................ 8

Alumni Section ....10

Continuing

Medical Education

Section ...............11

Duke Urologic

Assembly

Symposium .........12

DUKE UROLOGY UPDATEFall 2013

“We are especially excited about our

upcoming 46th annualDuke Urologic

Assembly symposium, which

will be held in Pinehurst in early

April, 2014.”

Glenn M. Preminger, MDChief of the Division of Urology

WELCOME

Page 2: DUKE UROLOGY UPDATE...Oct 13, 2012  · new imaging technology to perform partial nephrectomy for kidney cancer patients. The new imaging technology trademarked FireFly ®, by Intuitive

Cary N Robertson, MD, Assistant Professorship Announcement

Brant A. Inman, MD, MS, FRCSC

Theodore N. Pappas, MD, DistinguishedProfessor of Surgical Innovation, Interim Chair,Department of Surgery is pleased to an-nounce that Brant A. Inman, MD, MS, FRCSC

has been awarded the Cary N. Robertson,MD, Assistant Professorship

Brant A. Inman, MD, MS, FRCSC, Assis-tant Professor, Division of Urology, has beenawarded the Cary N. Robertson, MD, Assis-tant Professorship. This Duke Medicine en-dowed professorship honors our mostdistinguished physician-scientists who havedemonstrated extraordinary academic excel-lence in advancing medical science andhuman health.

Dr. Inman joined Duke in 2008 and is cur-rently Vice Chief of Urology Research, Directorof Clinical Trials for the Division of Urology,and a member of the Duke Institutional Re-view Board. His area of clinical expertise is thesurgical treatment of genitourinary cancers,and in particular bladder, kidney, penile, andtesticular cancer. From a research standpoint,Dr. Inman’s laboratory is focused on develop-ing novel therapies and diagnostic tests forbladder cancer as well as exploring the im-munologic aspects of genitourinary cancers.

Nationally, Dr. Inman is a core member ofthe bladder and penile cancer panels of theNational Comprehensive Cancer Network(NCCN). He is also on the Board of Directors

of the Society of Urological Oncology ClinicalTrials Committee and a member of the Blad-der Cancer Advocacy Network (BCAN). Hehas consulted for Blue Cross Blue Shield ofNorth Carolina and for the U.S. EnvironmentalProtection Agency on issues pertaining to uro-logic health. Internationally, Dr. Inman cur-rently serves as consulting editor for theJournal of European Urology.

Dr. Inman received his undergraduateand medical degrees from the University of Al-berta (Edmonton, Canada). He then com-pleted his urology residency at Laval University(Québec, Canada) and his urologic oncologyfellowship at the Mayo Clinic (Rochester, Min-nesota).

The Cary N Robertson Assistant Profes-sorship was made possible by donations fromEarnest and Mildred Mario, Stanley P. Porter,Ella Ann L. and Frank B. Holding Foundation,R.A Bryan Foundation, Sam and Nancy Chest-nut and the Samuel L. Phillips Foundation.This fund commemorates the extraordinarycontributions of current Duke Associate Pro-fessor, Dr. Cary N. Robertson, who continuesto serve Duke as a teacher and scientist, ad-vancing the field of urology.

2 • DUKE UROLOGY UPDATE • FALL 2013

FACULTY NEWS

FEATURED FACULTY:

Thomas Polascik, MD

Dr. Polascik, who recently returned fromthe 6th International Symposium for Imagingand Focal Therapy in Prostate Cancer, has beenactively engaged in this innovative treatmentapproach over the past 10 years.

“Focal therapy fundamentally changesthe approach to how prostate cancer is diag-

nosed and managed,” Thomas Polascik, DukeUrology.

Focal therapy is an emerging technical ap-proach that uses three dimensional imagingand targeted treatment to spare the prostategland, and preserve the urinary and sexualfunction of the patient. Advances in both im-aging and therapeutic technologies have en-abled urologists to approach treatment in anentirely new way. New multi-parametric MRItechnology can locate and target prostate can-cer lesions more precisely than ever before, andnew therapeutic devices such as cryotherapy,irreversible electroporation, and high intensityfrequency ultrasound (HIFU) are in variousstages of clinical trial and development. Thesenew imaging technologies and therapeutic de-vices may significantly reduce the role of tradi-tional surgical extirpation or radiation therapy.

Dr. Polascik is involved in several researchstudies and clinical trials examining new tech-nological releases. He is a firm believer thatnew technologies will improve patient out-comes, and safety, and lead not only to patientliving longer after prostate cancer, but with abetter quality of life.

Dr. Polascik has been at Duke since 1998.He received his MD, at the University ofChicago in 1991, and completed his UrologyResidency at Johns Hopkins in 1997. He has

risen to the rank of Professor of Urology, andis currently the Director of Urologic Oncologyand Director of the Genitourinary Focal Ther-apy Fellowship Program at Duke. He has pub-lished over 200 manuscripts on minimallyinvasive therapy, and oncologic urology, and isconsidered an international thought leader infocal therapy of prostate and renal cancers.

Dr. Polascik is, also, an experienced practi-tioner of robotic surgery and is using this newminimally invasive approach to deliver high-quality, more precise treatments to his patients.Using the da Vinci robotic system, Dr. Polascikprovides nerve-sparing robotic prostatectomyto his patients, and has recently begun using anew imaging technology to perform partialnephrectomy for kidney cancer patients. Thenew imaging technology trademarked FireFly®,by Intuitive Surgical, Inc. is an imaging systemthat allows surgeons to locate cancerous le-sions with more precision. The urologist injectsan indocyanine fluorescent dye into the pa-tient, which is then agitated with a laser, andglows fluorescent green.

“The robotic system gives me a greater de-gree of articulation than traditional la-paroscopy, and makes suturing much easierand more precise,” Thomas Polascik, Profes-sor of Surgery Duke Urology.

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DUKE UROLOGY UPDATE • FALL 2013 • 3

FACULTY AWARDS

George D. Webster, MB, FRCS was hon-ored by the Society of Urodynamics, FemalePelvic Medicine and Urogenital Reconstruc-tion for his leadership in fellowship trainingfor the specialty of Female Pelvic Medicineand Reconstructive Surgery. Dr. Webster,along with Drs. Jerry Blaivis, Ed McGuire andShlomo Raz were recognized as pioneers inthe development of this specialty at a dinnerand tribute entitled, “Standing on the Shoul-ders of Giants” in San Diego, CA, May 4,2013.

Edward N. Rampersaud Jr.,MD was selectedto serve on theNCCN Kidney Cancer Guidelinespanel.

Pei Zhong, Ph.D.was endowed asAnderson-RuppProfessor of Me-chanical Engineer-ing and MaterialsScience from July1, 2013 to June30, 2018.

Glenn M. Preminger, MD received the prestigiousSt. Paul’s Medal from the British Association ofUrological Surgeons for contributions to the fieldof Urology and was honored at the annual meet-ing in Manchester, England on June 20, 2013.

NEW FACULTY

Charles Scales, Jr, MD

Dr. Scales received his medical degreefrom Duke University in 2004 and stayed atDuke to complete both a urology residencyin 2011 and a fellowship in endo-urology in2012. He completed the Robert Wood John-son Foundation Clinical Scholars Program atthe University of California, Los Angeles in2013. His clinical interests include medicaland surgical management of kidney stonedisease, shock wave lithotripsy, medical andminimally-invasive management of benignprostatic hyperplasia, and endoscopic man-agement of urinary-tract obstruction. Dr.Scales returns to Duke as Assistant Professorof Urology and will be conducting his clinicalpractice at Duke University Hospital.

Sam Eaton, MD

Dr. Eaton received his medical degreefrom Columbia University College of Physi-cians and Surgeons in 2003. Following com-pletion of his urology residency at BostonUniversity in 2011, he completed a 2 yearendo-urology fellowship at Northwestern Uni-versity in Chicago that focused on both ad-vanced stone management as well aslaparoscopic and robotic surgery. His clinicalinterests include stone disease (including bothmedical and surgical management), prostatecancer (including robot-assisted prostatec-tomy), kidney cancer (focusing on minimallyinvasive and renal sparing techniques includ-ing robotic partial nephrectomy), upper tracturothelial cancer (including endoscopic man-agement and robotic assisted nephroureterec-tomy), upper tract obstruction (endoscopicand laparoscopic/robotic management of UPJobstruction and ureteral stricture disease), aswell as general urology. Dr. Eaton joins the fac-ulty as Assistant Professor of Urology and willpractice at Duke Urology of Raleigh.

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CLINICAL SECTION

Community Urology: Using Webinars for Patient Education"The internet haschanged howpatients learn andcope with theirdisease. Forphysicians, theinternet providesan opportunity to present wide-ranging and currentinformation in a variety ofteaching formats.The internet eliminates many of thetraditional barriers to patient education andempowers patients with 24 hour access tohigh-quality, patient-centered resources,"Aaron Lentz MD, Duke Urology of Raleigh.

In conjunction with Duke Raleigh Hospi-tal, Dr. Lentz and the team of urologists atDuke Urology of Raleigh have begun provid-ing patient education services by offering in-teractive webinars for patient education. Thewebinars are live presentations accessible tothe public through the Duke Raleigh website,and allow for “real-time” question and an-swer sessions with our physicians. After a fo-cused presentation, patients can submitquestions via text message, instant message,or Twitter. The topics presented to date havefocused on male-wellness including erectiledysfunction and low testosterone.

In the future, the webinars will be ex-panded to cover many more urologic condi-tions. After conclusion of the live session,each webinar is uploaded to the Internet andcan be accessed through YouTube(http://www.youtube.com/user/Duk-eRaleighNews) or the Duke Raleigh Hospi-tal website. We are very proud of thisoutreach project and anticipate partneringwith the hospital for additional patient serv-ice opportunities.

Delivering care to the patients of WakeCounty has given Duke Urologists a uniqueopportunity to our bring cutting edge thera-pies to a new patient population, and thestaff at Duke Raleigh Hospital provide out-standing care and service to our patients”Cary N. Robertson, Professor of Urology

About Duke Urologyof Raleigh

Duke Urology of Raleigh was estab-lished in 2010 on the Duke Raleigh HospitalCampus, and provides both inpatient andoutpatient care to the Wake County commu-nity. The hospital has welcomed the servicesand expertise of Duke Urologists, and weprovide a full service of oncological, recon-structive and general urological servicesusing the latest advances in minimally inva-sive and robotic techniques.

Location: 2480 Wake Forest Road,Raleigh, NC 27609

Urologic Cancer Survivorship Clinic

The Urologic Cancer Survivorship Clinicis designed to meet the quality-of-life needsof the growing number of cancer survivors.Minimally invasive treatments, for example,can help patients with leakage of urine and

voiding dysfunction. Infertility can be ad-dressed as well, with many new and effectivetherapies. The Survivorship Team is activelyinvolved in research to assess new treat-ments – such as the male sling for inconti-nence (the procedure involves placement ofa synthetic mesh in the groin to elevate theurethra and alter its position) – and out-comes studies that evaluate patient percep-tions of survivorship before and aftertreatment in the clinic.

Duke Urology is the first program in thecountry to offer specialized training in thetreatment of conditions that affect cancersurvivors’ quality of life. The GenitourinaryCancer Survivorship Fellowship at Duke Uni-versity and the Durham Veterans Administra-tion Medical Center is a one-year programthat offers the fellow an opportunity to be-come proficient in the evaluation and man-agement of all morbidities suffered bypatients who have undergone treatment forurologic and pelvic malignancies. This pro-gram focuses on managing the genitourinaryconcerns and complications of patients whohave undergone treatment for genitourinary,pelvic and other malignancies.

The operative scope of the fellowship in-cludes intra-abdominal and pelvic reconstruc-tion, urinary stricture and fistula disease,erectile dysfunction, urinary incontinenceand complex voiding dysfunction as a resultof prior cancer treatment. Fellows also par-ticipate in multidisciplinary projects includingurology, colorectal surgery, gynecology, radi-ation and medical oncology that attunethem to the continuum of care for this groupof patients. A structured training program in

4 • DUKE UROLOGY UPDATE • FALL 2013

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cancer survivorship confers a unique set ofmedical and surgical skills to urologists whowant to care for the burgeoning number ofcancer survivors, while improving our patient care and research opportunities atthe same time.

“We are really aleader in this area,”says Drew Peterson(Clinic Medical Direc-tor), acknowledging anupcoming AmericanCollege of SurgeonsCommission on Cancer(CoC) requirement forall accredited programsto offer a survivorshipprogram by 2015.

Men’s Health DayDuke Urologist’s participated in the An-

nual Duke Cancer Institute’s Men’s HealthDay held in Durham on September 22 and23, 2013. The event was held at Duke Uni-versity Hospital and Lincoln CommunityHealth Center. Duke Urologic Oncology fac-ulty, Lincoln Community Health providers,Durham Diabetes Coalition and Healing withCAARE Inc. offered advice on prostate can-cer risk assessment (based on the latest AUArecommendations), diabetes screening,blood pressure checks, and body mass index(BMI) screening. 19 faculty and staff for Urol-ogy attended the event and provided med-ical advice and screening services to theconference attendees.

“In general, many men do not visit adoctor regularly”, says Judd Moul, MD, DukeUrologist and James H Semans Professor ofSurgery, and this event brought many menin for a more comprehensive health assess-ment. Moul says the teams used the newAmerican Urologic Association (AUA)

prostate early detection guidelines to informmen about their current and future risk forprostate cancer while doing this in the con-text of their overall health status.

The Duke Urologic Oncology team per-forms its clinical work as a core part of theDuke Cancer Institute, in the newly openedDuke Cancer Center which has created amulti-disciplinary working environment wereurologists, medical oncologists, and radiationoncologists collaborate to provide the bestcare and treatment for cancer patients.

Resident Spotlight: Urology Care Foundation Award

Tara K. Ortiz, MD received aprestigious Urology Care FoundationResidency Research Award at theAUA annual meeting held in SanDiego, CA, May 4-8, 2013.

Dr. Ortiz, a third year Duke UrologyResident, is spending her research yearin basic science working under thementorship of Sherry Ross, MD(Pediatric Urology) and Patrick Seed, MD PhD(Pediatrics). She is utilizing this teams novel urinarytract infection-spinal cord injury rat model to betterunderstand the increased susceptibility of theneurogenic bladder to urinary tract infections, aleading cause of morbidity and mortality in patientswith a neurogenic bladder due to neurologicalinjury or abnormalities such as Spina Bifida. Bybetter understanding the mechanisms that resultin increased infections of the neurogenic bladder,improved treatment and preventive therapies can

be developed which willsubstantially improve patient carein this population.

“I am extremely proud thatthe research that we areconducting here at Duke has beenrecognized by the AUA, and thatthe hard-work and dedication thatTara has devoted to this projecthas paid off. Dr. Seed and I arelooking forward to mentoring herthrough her research yearexperience, as she completes thisproject,” Sherry Ross, MD PediatricUrology.

Tara’s research project titled:“The Role of Type I Pili in the Adherence andInvasion of Bladder Epithelium in a spinal Cordinjured rat model” was awarded the Russell ScottJr. Urology Research Award. The Urology CareFoundation is the official foundation of theAmerican Urological Association and offers theseawards to only four residents per year. Other awardrecipients included residents from Columbia,Loyola and Stanford.

“Tara’s recognition is a testament to thequality of faculty mentorship and institutional

support that our residents receive during theirresearch year experience here at Duke. We areproud to be supporting the development of thefuture generation of basic science researchers inUrology,” Steve Freedland, Urology ResearchResidency Director.

About Urology ResidentResearch at Duke

All residents in Urology at Duke spenda full year in dedicated academic research.This has been a long tradition at Duke andwe are now one of only a few programs inthe country to offer such an experience. Wefirmly believe that this year is invaluable intraining the future urological leaders of to-morrow. Whether our graduates will pursueacademic careers or full-time clinical practice,they need to be experts in understanding theliterature and how to interpret new scientificdiscoveries as they apply to their practice.What better way to understand the literature

DUKE UROLOGY UPDATE • FALL 2013 • 5

Andrew C. Peterson, MD

Judd Moul, MD

RESIDENT SECTION

Tara Ortiz, MD

Continued on next page.

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than to be a contributor? In addition, our res-idents gain a deep understanding of statistics– the language of how to communicate sci-entific findings. This year also provides valu-able time for our residents to reflect on theircareers and help formulate their career plans.Due in large part to this dedicated researchyear, Duke Urology has produced many lead-ers in urology from department chairs, toleading academicians, to premier clinicians.The dedicated research year is an importanttradition for Duke Urology and one that weare extremely proud of.

Duke hosts North Carolina Urology Resident Symposium

The Grandover Residency Retreat is anannual event where the three North Carolinaurology programs (Duke, UNC and Wake For-est) meet for a research and debate compe-tition. This is the 13th year of the event andwas attended by 28 residents and 27 faculty.A nationally renowned visiting professor isbrought in to give an educational lecture dur-ing the day’s events. This year, Dr. James East-ham, Chief of Urology at MemorialSloan-Kettering gave our keynote lecture on"Clinically Localized Prostate Cancer".

“This event gives residents the opportu-nity to network with their peers, and is an in-valuable learning experience. We hope tocontinue being able to fund this and othereducational opportunities for our residents inthe future,” Michael Ferrandino, MD, Asso-ciate Program Director, Duke Urology Resi-dency Program.

Duke was represented well in the re-search and debate competition. Dr. NicholasKuntz took first place for his research presen-tation titled "Striking Dose and Time De-pendency of Radiation Cystitis in the Rat:Repeat Cystometric Evaluation with SalineAlone and Potassium Chloride Challenge".Our residents, Rajeev Chaudry MD andMichael Granieri, MD, won their debates,with Duke bringing home 2 out of a possible4 awards in the debate competition.

2013 IncomingResidents(Class of 2019)

Bryce A Allio, MDMedical School: New York – University of Rochester

Eugene B. Cone, MDMedical School: Brown University

2013 Graduating ResidentsJohn G. Mancini, MD – Class of 2013Private Practice: United States Armed Forces

Suzanne B Stewart – Class of 2013Uro-Oncology Fellowship – Mayo Clinic, Min-nesota

Brian M Whitley – Class of 2013Private Practice: Sanford, North Carolina

“This past June, we graduated three out-standing chief residents, John Mancini,Suzanne Stewart and Brian Whitely. I just hadthe opportunity to see all three at Brian’s wed-ding in Durham last month. John (MilitaryUrology practice in Colorado), Suzanne (SUOFellowship, Mayo Clinic, Rochester, MN) andBrian (Group Practice, Sanford, NC) all appearto be enjoying their current positions. We areextremely proud of these individuals andknow that they will continue to support DukeUrology,” Glen Preminger, Division Chief,Duke Urology.

Resident HonorsZarine R. Balsara, MD, PhD was a

member of the Southeastern Section teamthat won the American Urological Associa-tion Residency Bowl Competition at the AUAannual meeting held in San Diego, CA, May4-8, 2013.

Tara K. Ortiz, MD received a UrologyCare Foundation 2013 Residency ResearchAward at the AUA annual meeting held inSan Diego, CA, May 4-8, 2013.

Tara K. Ortiz, MD was selected as a2014 Feagin Leadership Scholar on July 29,2013. This program gives scholars an oppor-tunity to develop and apply their leadershipskills to the Duke medical community and be-yond.

Michael A. Granieri, MD and RajeevChaudry, MD were winners for their uro-logic debates at the Annual North CarolinaUrology Resident Symposium (“Grandover”)held in Greensboro, NC, September 7, 2013.

Nicholas J. Kuntz, MD was first placewinner for his research presentation at theAnnual North Carolina Urology Resident Sym-posium (“Grandover”) held in Greensboro,NC, September 7, 2013.

6 • DUKE UROLOGY UPDATE • FALL 2013

RESIDENT Con’t.

Left to Right: Mancini, Stewart, Preminger,Whitley

Left to Right: Peterson, Balsara, Assimos, Preminger

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The Emergence ofHealth Services Research

Interview withChuck Scales

QWelcome back to Duke Campus,how does it feel to be back in NorthCarolina?

AIt is great to be back in North Car-olina. My wife and I are very excitedto return to Durham, which contin-

ues to grow and be a great place to raise afamily. It is also a real privilege to join the fac-ulty at Duke, where I was a medical studentand a resident.

QYou spent a year at UCLA as aRobert Wood Johnson Foundation/VA Clinical Scholar, how as your ex-

perience?

AThe Clinical Scholars Program atUCLA was a phenomenal learning ex-perience. Not only did I further de-

velop my research skills, but I also providedclinical care to underserved patients in LosAngeles County. Training in leadership andhealth policy were an integral part of the pro-gram. Finally, I had the opportunity to be partof the UCLA Health System team tasked withimproving the quality of care by reducing in-patient mortality.

QHealth Service Research is an emerg-ing area; could you explain the im-portance of this type of investigation

to the future of the field?

AHealth services research, also knownas population health science, focuseson four key aspects of health care: ac-

cess to care, understanding care delivery, thefinancing of patient care, and patient out-comes. The Institute of Medicine has notedthat important opportunities to improve thequality and safety of patient care exist acrossall medical specialties. Health services re-search provides the scientific underpinning toidentify opportunities to improve quality andsafety, design systems to deliver effective, pa-tient-centered care, and rigorously evaluateinnovative methods of patient care.

QWhat specific areas of research areyou planning to study?

AI am particularly interested in assess-ing the quality of urologic care deliv-ery and designing tools or

interventions to improve the quality of treat-ment for patients with both benign and ma-lignant urologic conditions. Current projectsfocus on understanding care delivery forolder adults with overactive bladder symp-toms, and creating decision aids to help pa-tients with kidney stones decide amongvarious treatment and prevention options.Other efforts will focus on identifying oppor-tunities and methods for improving care de-livery for patients with oncologicmalignancies.

QWhy did you decide that Duke wasthe place for you to begin this impor-tant work?

AThe rich clinical history of Duke Urol-ogy and Duke Surgery, combinedwith the expertise and research infra-

structure of the Duke Cancer Institute andthe Duke Clinical Research Institute made areturn to Durham very compelling. I’m ex-cited to have the opportunity to begin myclinical practice and research career at Duke.

Pediatric Urology Research

Research in thesection of Duke Pedi-atric Urology contin-ues to move forwardand grow with excit-ing research in basicscience, outcomesand clinical research.Dr. Tara Ortiz, a 3rdyear Duke Urologyresident is spendingher research year inbasic science working under the mentorshipof Dr. Sherry Ross and Dr. Patrick Seed, whois instrumental in designing and overseeingcollaborative laboratory projects.

Dr. Ortiz is working to better understandthe mechanisms that increase susceptibility tourinary tract infection in our novel neurogenic-UTI rat model. We are eager to learn moreabout these interactions since a better under-standing of urinary tract infections in the neu-rogenic bladder will encourage thedevelopment of preventive therapies for recur-rent UTIs in this population.

Dr. Erin McNamara, a former Duke Urol-ogy chief resident who is currently a fellow ofpediatric urology at Boston Children’s Hospital,presented the results of our project titled“Evaluation of Cold Ischemia for Preservationof Testicular Function during Partial Orchiec-tomy in the Rat Model” at the Society of Pedi-atric Urology national meeting in Las Vegas inSeptember. This study was inspired by the in-creased use of partial orchiectomy in childrenwith benign appearing testicular tumors anda recent study suggesting that cold ischemiaduring testicular torsion may be beneficial.We hypothesized that cold ischemia duringpartial orchiectomy in the pre-pubertal ratwould improve serum testosterone, spermcount and histology in the post-pubertal pe-riod. Interestingly, we found that there was nosignificant difference in testosterone levels orsperm count between cold and warm is-chemia but that histological parameters weresignificantly worse in the cold ischemia group.This study suggests that cold ischemia is notbeneficial during partial orchiectomy. The

DUKE UROLOGY UPDATE • FALL 2013 • 7

RESEARCH SECTION

Sherry Ross, MD

Continued on next page.

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manuscript for this study will be submitted forconsideration for publication in the Journal ofUrology.

Dr. Jonathan Routh is continuing his ef-forts to better understand urologic diseasesin children through outcomes research ef-forts. Dr. David Chu, a current Duke Urologychief resident and Dr. Routh were invited topresent their work as a podium presentationat the Society of Pediatric Urology nationalconference. This interesting study found thatin a large, nationwide pediatric cohort, radi-cal nephrectomy remained the most com-mon primary surgical intervention forpediatric renal tumors. However, over thestudy period nephron sparing surgery wasconsistently performed in 11% of pediatricrenal tumor cases. Importantly, they noted asignificant regional variation in the use ofnephron sparing surgery and associationwith a concomitant diagnosis of renal fail-ure/insufficiency, but not with any other clin-ical or socioeconomic factors. In addition, Dr.Routh and Dr. Scott Wang, a 3rd year Urol-ogy resident, are working very hard this yearon multiple projects including a project titled“Patterns in Emergency Care among Spina Bi-fida Patients: a Case-Control Study” wherethey will investigate the national patterns ofemergency care among spina bifida patientscompared to non-spina bifida controls. In ad-dition, they are utilizing the Surveillance, Epi-demiology, and End Results (SEER) databaseto examine nephron sparing surgery (NSS)outcomes and factors associated with NSSuse in Wilms Tumor. Last, we are very excitedto announce that Dr. Routh was recentlyawarded a K-12 grant for his work titled“Comparative Effectiveness of VesicoureteralTreatments in Children”. We are very proudof Dr. Routh and look forward to his contin-ued research efforts that enhance our knowl-edge and improve the care of children inpediatric urology.

RECENT SIGNIFICANT PAPERSCaso J, Masko EM, li JA, Poulton SH, De-whirst M, Pizzo SV, Freedland SJ. The Effectof Carbohydrate Restriction on Prostate Can-cer Tumor Growth in a Castrate MouseXenograft Model. Prostate 73(5): 449-454,April 2013.

Routh JC, Grundy PE, Anderson JR, Retik AB,Kurek KC. B7-h1 as a Biomarker for TherapyFailure in Patients with Favorable HistologyWilms Tumor. J Urol 189(4): 1487-1492,April 2013.

Singh AA, Jones LW, Antonelli JA, Gerber L,Calloway EE, Shuler KH, Freedland SJ,Grant DJ, Hoyo C, Bañez LL. Association Be-tween Exercise and Primary Incidence ofProstate Cancer: Does Race Matter? Cancer119(7): 1338-1343, April 2013.

Tsivian M, Caso JR, Kimura M, Polascik TJ.Renal Tumors in Solid Organ Recipients: Clin-ical and Pathologic Features. Urol Oncol31(3): 255-258, April 2013.

Abern MR, Owusu RA, Anderson MR, Ram-persaud EN, Inman BA. Perioperative Intrav-esical Chemotherapy in Non-Muscle-InvasiveBladder Cancer: A Systemic Review andMeta-Analysis. J Natl Compr Canc Netw.11(4): 477-484, April 2013.

Gupta RT, Kauffman CR, Polascik TJ, TanejaSS, Rosenkrantz AB. The State of ProstateMRI in 2013. Oncology 27(4): 262-270, April2013.

Walter LC, Fung KZ, Kirby KA, Shi Y, Espal-don R, O’Brien S, Freedland SJ, Powell AA,Hoffman RM. Five-Year Downstream Out-comes Following Prostate-Specific AntigenScreening in Older Men. JAMA Intern Med.173(10): 866-873, May 2013.

Inman BA, Harrison MR, George DJ. NovelImmunotherapeutic Strategies in Develop-ment for Renal Cell Carcinoma. Eur Urol63(5): 881-889, May 2013.

Beebe-Dimmer JL, Freedland SJ. AndrogenDeprivation Therapy: Further Confirmation ofKnown Harms. BJU Int 111(5): 690-691, May2013.

Thomas JA, Antonelli JA, Bañez LL, Hoyo C,Grant D, Demark-Wahnefried W, Platz EA,Gerber L, Shuler K, Eyoh E, Calloway E,Freedland SJ. Androgenetic Alopecia at Var-ious Ages and Prostate Cancer Risk in anEqual-Access Multiethnic Case-Control Seriesof Veterans. Cancer Causes Control 24(5):1045-1052, May 2013.

Allott EH, Masko EM, Freedland SJ. Obesityand Prostate Cancer: Weighing the Evidence.Eur Urol 63(5): 800-809, May 2013.

Masko EM, Allott EH, Freedland SJ. The Re-lationship Between Nutrition and ProstateCancer: Is More Always Better? Eur Urol63(5): 810-820, May 2013.

Fizazi KS, Higano CS, Nelson JB, Gleave M,Miller K, Morris T, Nathan FE, McIntosh S,Pemberton K, Moul JW. Phase III, Random-ized, Placebo-Controlled Study of Docetaxelin Combination with Zibotentan in Patientswith Metastatic Castration-Resistant ProstateCancer. J Clin Oncol. 31(14): 1740-1747,May 2013.

Clark PE, Spiess PE, Agarwal N, Biagioli MC,Eisenberger MA, Greenberg RE, Herr HW,Inman BA, Kuban DA, Kuzel TM, Lele SM,Michalski J, Pagliaro L, Pal SK, Patterson A,Plimack ER, Pohar KS, Porter MP, Richie JP,Sexton WJ, Shipley WU, Small EJ, Trump DL,Wile G, Wilson TG, Dwyer M, Ho M. PenileCancer: Clinical Practice Guidelines in Oncol-ogy. J Natl Compr Canc Netw. 11(5): 594-615, May 2013.

Inman BA, Etienne W, Rubin R, Owusu RA,Oliveira TR, Rodriques DB, Maccarini PF,Stauffer PR, Mashal A, Dewhirst MW. The Im-pact of Temperature and Urinary Con-stituents on Urine Viscosity and its Relevanceto Bladder Hyperthermia Treatment. Int J Hy-perthermia 29(3): 206-210, May 2013.

Klink JC, Tewari AK, Masko EM, Antonelli J,Febbo PG, Cohen P, Dewhirst MW, Pizzo SV,Freedland SJ. Resveratrol Worsens Survivalin SCID Mice with Prostate CancerXenografts in a Cell-Line Specific Manner,Through Paradoxical Effects on OncogenicPathways. Prostate 73(7): 754-762, May2013.

8 • DUKE UROLOGY UPDATE • FALL 2013

RESEARCH Con’t.

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Moreira DM, Bañez LL, Presti JC Jr, AronsonWJ, Terris MK, Kane CJ, Terris MK, AmlingCL, Freedland SJ. High Serum Folate is As-sociated with Reduced Biochemical Recur-rence after Radical Prostatectomy: Resultsfrom the SEARCH Database. Int Braz J Urol39(3): 312-319, May-June 2013.

Solomon KR, Allott EH, Freeman MR, Freed-land SJ. Re: Dysregulation of CholesterolHomeostasis in Human Prostate CancerThrough Loss of ABCA1. Eur Urol 63(6):1128-1129, June 2013.

Muller RL, Gerber L, Moreira DM, AndrioleG Jr, Hamilton RJ, Fleshner N, Parsons JK,Freedland SJ. Obesity is Associated with In-creased Prostate Growth and AttenuatedProstate Volume Reduction by Dutasteride.Eur Urol 63(6): 1115-1121, June 2013.

Moul JW. Prostate Cancer: Active Surveil-lance in African American Men. Nat RevUrol. 10(6): 311-312, June 2013.

Wang AJ, Goldsmith ZG, Wang C, NguyenG, Astroza GM, Neisius A, Iqbal MW, NevilleAM, Lowry C, Toncheva G, Yoshizumi TT,Preminger GM, Ferrandino MN, LipkinME. Obesity Triples the Radiation Dose ofStone Protocol Computerized Tomography. JUrol 189(6): 2142-2146, June 2013.

Wu C, Aronson WJ, Terris MK, Presti JC Jr.,Amling CL, Freedland SJ. Diabetes PredictsMetastasis after Radical Prostatectomy inObese Men: Results from the SEARCH Data-base. BJU Int. 111(8): E310-318, June 2013.

Inman BA, Abern MR. Interpreting a studyon bladder cancer screening. Eur Urol 64(1):48-50, July 2013.

Magnon C, Hall SJ, Lin J, Xue X, Gerber L,Freedland SJ, Frenette PS. Autonomic nervedevelopment contributes to prostate cancerprogression. Science 341(6142): 1236361,July 2013.

Teeter AE, Presti JC Jr, Aronson WJ, Terris MK,Kane CJ, Amling CL, Freedland SJ. Donomograms designed to predict biochemicalrecurrence (BCR) do a better job of predict-ing more clinically relevant prostate canceroutcomes than BCR? Urology 82(1): 53-58,July 2013.

Goldsmith ZG, Oredein-McCoy O, Gerber L,Bañez LL, Sopko DR, Miller MJ, PremingerGM, Lipkin ME. Emergent ureteric stent vspercutaneous nephrostomy for obstructiveurolithiasis with sepsis: Patterns of use andoutcomes from a 15-year experience. BJU Int112(2): E122-128, July 2013.

Freedland SJ. Dietary fat and reducedprostate cancer mortality: Does the type offat matter? JAMA Intern Med 173(14): 1326-1327, July 2013.

Inman BA.Words of wisdom: Re: Final re-sults of an EORTC-GU cancers group ran-domized study of maintenance bacillusCalmette-Guerin in intermediate- and high-risk Ta, T1 papillary carcinoma of the urinarybladder: One-third dose versus full dose and1 year versus 3 years of maintenance. EurUrol 64(1): 171-172, July 2012.

Tsivian M, Abern MR, Qi P, Polascik TJ.Short-term functional outcomes and compli-cations associated with transperineal tem-plate prostate mapping biopsy. Urology82(1): 166-170, July 2013.

Madden-Fuentes RJ, McNamara ER, Lloyd JC,Wiener JS, Routh JC, Seed PC, Ross SS.Variation in definitions of urinary tract infec-tions in spina bifida patients: A systematic re-view. Pediatrics 132(1): 132-139, July 2013.

Gbadegesin RA, Brophy PD, Adeyemo A,Hall G, Gupta IR, Hains D, Bartkowiak B, Ra-binovich CE, Chandrasekharappa S, Hom-stad A, Westreich K, Wu G, Liu Y, HolandaD, Clarke J, Lavin P, Selim A, Miller S, WienerJS, Ross SS, Foreman J, Rotimi C, Winn MP.TNXB mutations can cause vesicoureteral re-flux. J Am Soc Nephrol 24(8): 1313-1322,July 2013.

Tsivian M, Polascik TJ. Bilateral focal abla-tion of prostate tissue using low-energy di-rect current (LEDC): A preclinical caninestudy. BJU Int 112(4): 526-530, August 2013.

Preminger GM. Micro-percutaneous ne-phrolithotomy (micro-PNL) vs retrogradeintra-renal surgery (RIRS): dealer’s choice?The devil is in the details. BJU Int 112(3): 280-281, August 2013.

Freedland SJ, Gerber L, Reid J, Welbourn W,Tikishvili E, Park J, Younus A, Gutin A, San-gale Z, Lanchbury JS, Salama JK, Stone S.Prognostic utility of cell cycle progressionscore in men with prostate cancer after pri-mary external beam radiation therapy. Int JRadiat Oncol Biol Phys 86(5): 848-853, Au-gust 2013.

Cookson MS, Roth BJ, Dahm P, Engstrom C,Freedland SJ, Hussain M, Lin DW, LowranceWT, Murad MH, Oh WK, Penson DF, KibelAS. Castration-resistant prostate cancer:AUA guideline. J Urol 190(2): 429-438, Au-gust 2013.

Carter HB, Albertsen PC, Barry MJ, Etzioni R,Freedland SJ, Greene KL, Holmberg L,Kantoff P, Konety BR, Murad MH, Penson DF,Zietman AL. Early detection of prostate can-cer: AUA guideline. J Urol 190(2): 419-426,August 2013.

van den Bergh RC, Albertsen PC, BangmaCH, Freedland SJ, Graefen M, Vickers A,van der Poel HG. Timing of curative treat-ment for prostate cancer: A systematic re-view. Eur Urol 64(2): 204-215, August 2013.

Lotan Y, Amiel G, Boorjian SA, Clark PE,Droller M, Gingrich JR, Guzzo TJ, Inman BA,Kamat AM, Karsh L, Nielsen ME, Smith ND,Shariat SF, Svatek RS, Taylor JM; Bladder Can-cer Think Tank, and Bladder Cancer Advo-cacy Network. Comprehensive handbook fordeveloping a bladder cancer cystectomydatabase. Urol Oncol 31(6): 812-826, Au-gust 2013.

Balsara ZR, Ross SS, Dolber PC, WienerJS, Tang Y, Seed PC. Enhanced susceptibil-ity to urinary tract infection in the spinal cord-injured host with neurogenic bladder. InfectImmun 81(8): 3018-3026, August 2013.

Kokorowski PJ, Routh JC, Hubert K, GrahamDA, Nelson CP. Trends in revision circumci-sion at pediatric hospitals. Clin Pediatr 52(8):699-706, August 2013.

DUKE UROLOGY UPDATE • FALL 2013 • 9

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The Duke Youthful Society of UrologyResidents Interested in Advancement (DY-SURIA) was established in 1966 and is the of-ficial alumni association of Duke Urology.DYSURIA currently has over 295 activealumni and honorary members and is a keycontributor to the success of the Duke Urol-ogy Residency Program

Everett Anderson Education Fund

It is with the greatest of gratitude thatwe are proud to announce the E. EverettAnderson Education Fund, a new fundraisinginitiative to honor the educational legacycultivated by Dr. Anderson in his more than48 years of dedicated service to DukeUniversity. This new fund will be used tosupport the educational needs of theUrology Residency Program.

“Everett has been an integral fixture inDuke Urology for over 40 years and he con-tinues to educate our medical students, resi-dents and fellows. Everett has forgottenmore in Urology than I will ever know,”Glenn Preminger MD, Division Chief, DukeUrology.

Edward Everett Anderson was born inDurham, North Carolina on May 10, 1932.He was educated at Phillips Academy, en-tered Duke and received his BS in 1954 andMD in 1958. He trained at Duke, Yale, theWashington School of Medicine in Seattleand the Peter Bent Brigham Hospital, Boston.

He joined the Urology staff at Duke Univer-sity Medical Center in 1965, became Assis-tant Professor in 1966, Associate Professor in1969 and Professor in 1972. He has had ac-tive reserve duty entering as Captain in 1961and exiting as Lieutenant Colonel in 1971.

After his retirement in 2002, Dr. Ander-son assumed the role of resident mentor atthe Durham VA Hospital where he continuesto teach and advise residents two days aweek. To those of us at Duke, Everett is bestknown for his teaching and patient care skills,as well as his wonderful sense of humor.

“The pressures of modern healthcareeconomics on educational funding, hasmade it challenging for academic programsto continue to find the financial resources toenrich the resident educational experience,”Drew Peterson, Program Director, Duke Urol-ogy Residency Program.

The E. Everett Anderson Education Fundwill be funded by an annual gift giving cam-paign that we are asking our alumni to sup-port.

Reinvigoration of theDYSURIA Community

The Duke Urology Residency Programhas been training residents since 1966 andhas graduated more than 100 leaders in thefield. The proud legacy of the Duke programis the success of its graduates and their con-tributions to the lives of patients with urolog-ical diseases across the country. The currentreputation and success of the Duke UrologyResidency Program is the result of the effortsof all graduates of the program, who havehelped shape the program and through theirindividual achievements continue to gener-ate a source of pride for the Program.

The modern pressures of clinical prac-tice, education and research make it chal-lenging for us all to come together as acommunity, and as a result we are announc-ing a new structure for the DYSURIA group,that will now be led by an alumni committee

DYSURIA CommitteeCo-Chairs

A new committee is being formed tohelp manage and shape the future of DY-SURIA. Drs. John Wiener and Jeff Taber willbe working to establish the committee to im-prove networking and communication; de-velop scientific and social programs, andraise funds to support current Duke residents.

In 2014, DYSURIA will increase its net-working opportunities and invites alumni toattend the following events:

DYSURIA Calendar 2014

April 5, 2014 DYSURIA Dinner at theDuke Urology Assembly

Pinehurst, North Carolina

May 16, 2014 [tentative]DYSURIA Cocktail Party at the AUA

Orlando, Florida

June 20, 2014DYSURIA 5th and 25th Year

Graduates at the Annual Chief Residents’

Graduation DinnerDurham, North Carolina

10 • DUKE UROLOGY UPDATE • FALL 2013

ALUMNI SECTION

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DUKE UROLOGY UPDATE • FALL 2013 • 11

CONTINUING MEDICALEDUCATION SECTION

Morris Center for Research Lectureship

The 2013 Duke Tuesday in Urology, Mor-ris Center for Research Lectureship was heldon July 23, 2013. The guest lecturer wasThomas W. Jarrett, MD, Chairman of Urologyat George Washington University, who spokeon “What is meant by Limited Life Expectancyand How It Relates to Urologic Malignancies.”Dr. Jarrett attended Duke University as an un-dergraduate with current Duke Urology fac-ulty member, Dr. John Wiener and was theUrology Residency Program Director atGeorge Washington University when currentDuke Faculty Member, Sherry Ross was atrainee there.

The event was attended by over 100members of the urologic community acrossthe state. Duke Urology continues to provideinvaluable educational forums to local, re-gional and national practicing urologists. TheDuke Tuesday Educational Series is held threetimes per year, and provides local and regionalurologists with the opportunity to learn fromnational leaders across the country.

The Morris Lectureship was made possi-ble by the kind donation from the Morris Fam-ily Foundation.

DukeTuesdayLectureSeries - November

Dean G. Assimos, MD, Chairman ofUrology at the University of Alabama-Birm-ingham was the Duke Tuesday guest facultyspeaker on November 12. Dr. Assimos deliv-ered the keynote lecture on “Urinary Oxalate:How Did It Get There and How to Reduce It.”Duke faculty speaking that day includedStephen J. Freedland, MD (Lifestyle andProstate Diseases), Michael R. Harrison, MD(GU Oncologist – Treatments for MetastaticRenal Carcinoma), and Michael E. Lipkin, MD(Imaging for Urolithiasis).

2014 Duke TuesdayEducation Series

February 11, 2014Christopher Saigal, MD, MPH

Professor and Vice Chair of Urology,UCLA

July 15, 2014Morris Center for Research Lectureship

Joel B Nelson, MDProfessor and Chair of Urology

University of Pittsburgh School of Medicine

November 4, 2014John E. Dees LectureshipJohn W Brock III, MDProfessor and Chief,

Division of Pediatric Urology, Monroe Carell Jr. Children’s Hospital,

Vanderbilt University

To register for the Duke Tuesday Educa-tion Series for 2014 register at the DukeCME Website or contact Robin Phillips,CMECoordinator, [email protected]. This lecture series offers 3.0 PMAContinuing Education Credits per lecture.

Duke Urologic Assembly2014 Symposium

The 46th Annual Duke Urologic Assem-bly (DUA) will return to its roots and be heldApril 3 – April 6, 2014 in the historic villageof Pinehurst for the first time since 1992.This year’s format includes a dedicated dayfocused on oncology. Thursday, April 3rd willbe the Duke Urologic Cancer Symposiumjointly hosted by Duke Urology and the DukeCancer Institute, with 13 Duke urologic on-cologists, medical oncologists, and radiationoncologists speaking on the latest diagnostic,medical, and surgical aspects of urologic can-cer management. Friday, April 4th – Sunday,April 6th will be focus on urologic diseasesand treatments.

Attendees have the opportunity toenjoy the spa facilities, family recreational ac-tivities, and any one of Pinehurst’s eightworld-class golf courses. As a special event,a limited number of golf tee times on theworld famous Pinehurst No. 2 Golf Coursehave been reserved for Friday afternoon. Thiscourse will also host the US Open and USWomen’s Open Championships just twomonths later. If you wish to play No. 2 thatday, please contact Robin Phillips at 919-668-3532.

Registration information will be avail-able on the Urology website at http://urol-ogy.surgery.duke.edu/cme. To reserve yourhotel room and tees for additional rounds ofgolf, please call the Pinehurst Resort directlyat 1-877-403-2874. A block of rooms isbeing held at a special rate but you will needto book early as these are in high demand.

History of the DUAThe Duke Urologic Assembly was estab-

lished to meet the scientific and educationalneeds of Duke Alumni and practicing urolo-gists. The first meeting was held in 1966 inthe Jack Tar Hotel in Durham and was namedthe Symposium Urologic Education.

DonationsCharitable gifts are a driving force in the

current success and future achievements ofour physicians, educators, and scientists. Ifyou are interested in learning more about sup-porting Duke Urology, please contact JillianReam, Duke Medicine Development andAlumni Affairs, [email protected] or919-385-3197.

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12 • DUKE UROLOGY UPDATE • FALL 2013

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DUKE UROLOGY UPDATE • FALL 2013 • 13

Thursday, April 3, 2014Session I ONCOLOGY: Localized Prostate Cancer8:30 am Welcome/Opening Remarks8:35 am Active Surveillance and Surgery

– Moul8:55 am Contemporary Radiation Therapy

– Lee9:15 am Hormones and Other Systemic

Therapies in Non-Metastatic Prostate Cancer – George

9:35 am Racial Disparities in Prostate Cancer – Patierno

9:55 am Case Discussion10:20 am Break

Session II ONCOLOGY: Advanced Renal Cell Carcinoma10:30 am Differences in Outcome Between

Academic and Community Medical Centers – Hirsch

10:50 am Treatment Selection for Newly Metastatic Kidney Cancer – George

11:10 am What To Do When First Line Therapy Fails – Harrison

11:30 am Case Discussion12:00 pm Lunch in Carolina Dining Room

Session III ONCOLOGY: Bladder Cancer1:00 pm Surgery for Locally Advanced

Bladder Cancer – Inman1:20 pm Neo-adjuvant and Adjuvant

Therapy: Who Should Get It and Why – Milowsky

1:40 pm Chemoradiation for Bladder Cancer – Lee

2:00 pm Panel Discussion2:20 pm Break

Session IV ONCOLOGY: Immunotherapy in Urologic Cancers2:30 pm Cancer and the Immune System:

The Basics – Nair2:50 pm Immunotherapy and Surgery

– Inman3:10 pm Immunotherapy in Renal Cell

Carcinoma: Is There Still a Role forThis – Inman

3:30 pm Case Discussion3:50 pm Break

Session V ONCOLOGY: Advanced Prostate Cancer4:00 pm Natural History and Hormonal

Therapy for Metastatic Prostate Cancer – Freedland

4:20 pm What To Do When Hormonother-apy Fails – George

4:40 pm Cutting Edge: Molecular Charac-terization of Prostate Cancer – Harrison

5:00 pm Panel Discussion5:30 pm Adjourn

Friday, April 4, 2014Session VI ONCOLOGY: Renal Cell Carcinoma8:00 am Cytoreductive Nephrectomy and

Metastasectomy – Rampersaud8:20 am Surveillance of Renal Masses

– Uzzo8:40 am Management of Alternative

Histologies in RCC – George9:00 am Panel Discussion9:20 am Break

Session VII UROLOGY: Focal Therapy9:30 am Modern Imaging of Renal and

Prostate Tumors-Impact on Focal Ablative Therapies – Gupta

9:50 am Prostate Focal Therapy: Cryotherapy and Nanoknife – Polascik

10:10 am Prostate HIFU – Robertson10:30 am Renal Focal Therapy: Cryotherapy

and Radiofrequency Ablation – Polascik

10:50 am Panel Discussion11:10 am Break

Session VIII UROLOGY: Other GU Malignancies11:20 am Embracing a Neoadjuvant

Approach for Upper Tract Urothelial Tumors – Walther

11:40 am Early Stage Testis Cancer: How to Decide Which Avenue to Use – Robertson

12:00 pm Panel Discussion12:20 pm Adjourn

Saturday, April 5, 2014Session IX UROLOGY: Stones8:00 am Adjuvant Medical Therapy

Following Surgical Stone Management – Preminger

8:20 am AUA Guidelines for Imaging Known or Suspected Ureteral Calculi – Lipkin

8:40 am Ureteral Stone Management - SWL v URS - Are we doing the right thing – Scales

9:00 am Panel Discussion9:20 am Break

Session X UROLOGY: Endourology/Robotics9:30 am UPJ Obstruction – Ferrandino9:50 am Robotics – Eaton

10:10 am Endoscopic Management of Ureteral Strictures – Lipkin

10:30 am Open Management of Ureteral Strictures – Peterson

10:50 am Panel Discussion11:10 am Break

Session XI UROLOGY: Renal Masses11:20 am Radiologic Work Up of Renal

Masses – Leder11:40 am VICTOR A. POLITANO

LECTURESHIP presented by RobertUzzo, MD – Nephrometry Scores

12:20 pm Adjourn

Sunday, April 6, 2014Session XII UROLOGY: Pelvic Floor & Male Reconstruction8:00 am Management of Vesicovaginal

and Ureterovesical Fistulae – Le8:20 am Rectourethral Fistula; Algorithmic,

Team-based Approach to a Complex Problem – Peterson

8:40 am Pharmacotherapy for Benign Urinary Tract Dysfunctions-State of the Art 2014 – Fraser

9:00 am Panel Discussion9:20 am Break

Session XIII UROLOGY: Andrology9:30 am AUA Vasectomy Guidelines

– Viviano9:50 am Non-Surgical Management of

Peyronie’s Disease: Options and Efficacy – Lentz

10:10 am Advances in Medical Therapy for BPH – Scales

10:30 am Testosterone Replacement Therapy and Prostate Cancer: An Update – Viviano

10:50 am Panel Discussion11:10 am Break

Session XIV UROLOGY: Pediatrics11:20 am Contemporary Management of

Vesicoureteral Reflux – Routh11:40 am Urinary Tract Infection in the

Neurogenic Bladder: What We’ve Learned – Ross

12:00 pm Managing Pediatric Voiding Dysfunction – Wiener

12:20 pm Panel Discussion12:40 pm Closing Remarks12:50 pm Adjourn

Agenda

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Faculty

14 • DUKE UROLOGY UPDATE • FALL 2013

2014 CONFERENCE MEDICAL DIRECTORS John S. Wiener, MDAssociate Professor of SurgeryAssociate Professor in PediatricsSection Head, Pediatric UrologyDepartment of Surgery, Division of UrologyDuke University Medical Center

Daniel J. George, MDAssociate Professor of MedicineAssociate Professor in UrologyDirector, GU Oncology, Duke Cancer InstituteDepartment of Medicine, Medical OncologyDuke University Medical Center

2014 Victor A. Politano, MD, Lectureship GUEST FACULTY SPEAKERRobert Uzzo, MD, FACSG. Willing “Wing” Pepper Chair in Cancer ResearchProfessor and Chairman, Department of SurgeryFox Chase Cancer CenterTemple University School of MedicineFox Chase Cancer CenterPhiladelphia, PA

GUEST FACULTYRichard C. Rink, MD, FAAP, FACSRobert A. Garrett Professor, Pediatric UrologyRiley Hospital for ChildrenIndiana University School of MedicineIndianapolis, Indiana

Matthew I. Milowsky, MDAssociate Professor of MedicineSection Chief, Genitourinary Oncology ServiceUNC Lineberger Comprehensive Cancer CenterChapel Hill, North Carolina

DUKE UNIVERSITY FACULTYSamuel H. Eaton, MDAssistant ProfessorDepartment of Surgery, Division of Urology

Michael N. Ferrandino, MDAssistant Professor of SurgeryDirector, Minimally Invasive Urologic SurgeryAssociate Residency Program DirectorDepartment of Surgery, Division of Urology

Matthew O. Fraser PhDAssociate Professor of SurgeryDepartment of Surgery, Division of Urology

Stephen J. Freedland, MDAssociate Professor of SurgeryAssociate Professor in PathologyDepartment of Surgery, Division of UrologyMember of the Duke Cancer Institute

Rajan T. Gupta, MDAssistant Professor of RadiologyDirector, Abdominal Imaging Fellowship ProgramDepartment of Radiology, Division of Abdominal Imaging

Michael R. Harrison, MDAssistant Professor of MedicineDepartment of Medicine, Division of OncologyMember of the Duke Cancer Institute

Bradford R. Hirsch, MDAssistant Professor of MedicineDepartment of Medicine, Division of OncologyMember in the Duke Clinical Research Institute

Brant A. Inman, MD, MS, FRCSCCary N. Robertson, MD, Assistant ProfessorDepartment of Surgery, Division of UrologyMember of the Duke Cancer Institute

Ngoc-Bich (Nikki) Le, MD Assistant Professor of SurgeryDepartment of Surgery, Division of Urology

Richard A. Leder, MDAssociate Professor of RadiologyClinical Associate in SurgeryDepartment of Radiology, Division of Abdominal Imaging

W. Robert Lee, MD, MEd, MSProfessor of Radiation OncologyAssociate Professor of SurgeryDepartment of Radiation Oncology Member of the Duke Cancer Institute

Aaron C. Lentz, MDAssistant Professor of SurgeryDepartment of Surgery, Division of Urology

Michael E. Lipkin, MDAssistant Professor of SurgeryDepartment of Surgery, Division of Urology

Judd W. Moul, MD, FACSJames H. Semans, MD, Professor of Surgery Professor of AnesthesiologyDepartment of Surgery, Division of UrologyMember of the Duke Cancer Institute

Smita Kesavan Nair, PhDAssociate Professor of SurgeryDepartment of Surgery, Division of Surgical SciencesMember of the Duke Cancer Institute

Steven R. Patierno, PhDDeputy Director, Duke Cancer InstituteProfessor of MedicineDepartment of Medicine, Division of Oncology

David F. Paulson, MDProfessor Emeritus of SurgeryDepartment of Surgery, Division of Urology

Andrew C. Peterson, MDAssociate Professor of SurgeryDepartment of Surgery, Division of Urology

Thomas J. Polascik, MDProfessor of SurgeryDirector, Society of Urologic Oncology ProgramDirector, Genitourinary Program on Focal TherapyDepartment of Surgery, Division of UrologyMember of the Duke Cancer Institute

Glenn M. Preminger, MDJames F. Glenn, MD, Professor of UrologyChief, Division of Urologic SurgeryDepartment of Surgery, Division of Urology

Edward N. Rampersaud Jr., MDAssistant Professor of SurgeryDepartment of Surgery, Division of Urology

Cary N. Robertson, MDAssociate Professor of SurgeryPractice Director, Duke Urology of RaleighDirector, GU Surgical Oncology, Duke Raleigh Cancer CenterMember of the Duke Cancer Institute

Sherry S. Ross, MD Assistant Professor of SurgeryAssistant Professor in PediatricsDirector of Pediatric Urology ResearchDirector of Pediatric Urology Stone ClinicDepartment of Surgery, Division of Urology

Jonathan C. Routh, MD, MPHAssistant Professor of SurgeryAssistant Professor in PediatricsDepartment of Surgery, Division of Urology

Charles D. Scales Jr., MD, MSHSAssistant Professor of SurgeryDepartment of Surgery, Division of UrologyMember in the Duke Clinical Research Institute

Charles J. Viviano, MD, PhDAssistant Professor of SurgeryDepartment of Surgery, Division of Urology

Philip J. Walther, MD, PhD, FACSProfessor of SurgeryAssociate Professor of Pathology Department of Surgery, Division of Urology Chief of Urology, VA Medical Center, DurhamMember Duke Cancer Institute

Page 15: DUKE UROLOGY UPDATE...Oct 13, 2012  · new imaging technology to perform partial nephrectomy for kidney cancer patients. The new imaging technology trademarked FireFly ®, by Intuitive

DUKE UROLOGY UPDATE • FALL 2013 • 15

LEADING EDGE UROLOGY

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Page 16: DUKE UROLOGY UPDATE...Oct 13, 2012  · new imaging technology to perform partial nephrectomy for kidney cancer patients. The new imaging technology trademarked FireFly ®, by Intuitive

Duke UrologyDivision of the Department of Surgery

Duke South, White Zone, Rm 1571-AMail: DUMC 3707, Durham, NC 27710

First Class MailU.S. Postage

P A I DPermit No. 60Durham, NC

COURSE DESCRIPTIONWith over eight decades of experience in car-

ing for patients with urologic diseases, Duke’s Di-vision of Urologic Surgery has established itself asa world leader in urologic care, research, and ed-ucation. The Duke Urologic Assembly began inthe 1970’s and was held annually at Pinehurst; weare excited to return to our roots at Pinehurst forthe first time in decades. LEADING EDGE UROL-OGY: 46th Annual Duke Urologic Assembly willevaluate the most recent advances in the diagnos-tic evaluations, therapeutic options, managementof complications, and technologies that provideleading edge care to patients. Participants will beengaged through moderated discussions and in-teractive lectures on the latest evidence-based ap-proaches to managing a wide range of urologicconditions across the spectrum of life.

In partnership with our colleagues in theDuke Cancer Institute we will designate Thursdayof the DUA for the DUKE UROLOGIC CANCERSYMPOSIUM; a full day CME event featuring lec-tures by Duke and guest Medical Oncologists, Ra-diation Oncologists, and Urologists speaking onthe latest diagnostic, medical, and surgical as-pects of urologic cancer management. There willbe separate as well as combined registration forthe Cancer Symposium with the DUA.

STATEMENT OF NEEDImprovements in the treatment of urologic

conditions generate a great need for knowledgeand up-to-date information for providers andhealth care professionals. An outstanding rosterof speakers in a comprehensive, scientific pro-gram encompassing the sub-specialties of urology,as well as medical and radiation oncologists treat-ing urologic malignancies has been assembled.This conference is an integral part of continuingeducation for health care professionals nation-wide.

TARGET AUDIENCEAddressing current issues and technologies

in the practice of Urology, this conference will en-hance knowledge in treating urologic conditionsand help improve patient care by Urologists; Med-ical Oncologists; Radiation Oncologists; Internal,Family and Geriatric Medical Practitioners; Physi-cian Assistants; Radiation Technicians; Nurse Prac-titioners; Nurses; Residents; and other AlliedHealth Medical Staff.

LEARNING OBJECTIVES• Evaluate and outline management options for

the patient with various urologic conditions • Review the latest advances in the treatment of

advanced prostate cancer• Identify latest updates in management of

bladder cancer, upper tract urothelial cancer, renal cell carcinoma, and adrenal disorders

• Extend improved patient counseling and generate patient satisfaction regarding therapychoice

• Examine concepts of the medical managementof nephrolithiasis, as well as surgical therapy ofboth renal and ureteral calculi

ACCREDITATIONThe Duke University School of Medicine is ac-

credited by the Accreditation Council for Contin-uing Medical Education (ACCME) to providecontinuing medical education for physicians.

CREDIT DESIGNATIONThe Duke University School of Medicine des-

ignates this live activity for a maximum of 20AMA PRA Category 1 Credit(s)™. Physiciansshould only claim credit commensurate with theextent of their participation in the activity.

DUKE UROLOGIC ASSEMBLY • 2014 SYMPOSIUM