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  • 8/12/2019 Drug Study for Sale

    1/5

    Generic

    name

    Brand

    Name

    Mechanism of

    Action

    Indications Contra-indications Adverse Effects Nursing Consideration

    1.Celecoxib

    Classification

    :NSAID,

    Analgesic(nonopioid),

    Specific

    COX-2enzyme

    bloce!

    Dosage:

    2"" mgre!uenc":

    #ID p!n fopain

    #oute:

    O!al

    Celeb!ex Celecoxib $asCOX-2 specific

    in$ibi%o!yac%i&i%y' I%

    in$ibi%s %$econ&e!sion of

    a!ac$idonic

    acid %op!os%aglandins

    $ile $a&ingno effec% on %$e

    fo!ma%ion of

    p!os%aglandins%$a% media%e

    %$e no!mal$omeos%asis in

    %$e I %!ac%,idneys and

    pla%ele%s

    ca%alyzed byCOX-*'

    Ac+%e andlong-%e!m

    %!ea%men% ofsigns and

    symp%oms of!$e+ma%oid

    a!%$!i%is and

    os%eoa!%$!i%is

    ed+c%ion of

    %$e n+mbe! ofcolo!ec%al

    polyps infamilial

    adenoma%o+spolyposis

    (A.)

    /anagemen%

    of ac+%e pain

    0ype!sensi%i&i%yincl+ding %$ose in

    $om a%%acs ofangioedema, !$ini%is

    and +!%ica!ia $a&ebeen p!ecipi%a%ed by

    aspi!in, NSAIDs o!

    s+lfonamides'Se&e!e $epa%ic

    impai!men%1 se&e!e$ea!% fail+!e1

    inflamma%o!y boel

    disease1 pep%ic +lce!1!enal impai!men%

    (C!Cl 3" ml4min)1p!egnancy and

    lac%a%ion'

    Abdominal pain

    Dia!!$ea

    Na+sea

    5dema Dizziness

    0eadac$e

    Insomnia

    +ppe! !espi!a%o!y

    %!ac% infec%ions

    !as$

    .o%en%ially a%al6

    exfolia%i&e

    de!ma%i%is

    S%e&ens-7o$nson

    synd!om

    %oxic epide!mal

    nec!olysis'

    *' Info!m %$e pa%ien% %o %ae

    d!+g i%$ food o! meals ifI +pse% occ+!s'

    2' Info!m %$e pa%ien% %o %ae

    only %$e p!esc!ibeddosage1 do no% inc!ease

    dosage'

    3' Info!m %$e pa%ien% %$a%

    $e4s$e may expe!ience%$ese side effec%s6

    Dizziness, d!osiness(a&oid d!i&ing o! %$e +se

    of dange!o+s mac$ine!y$ile %aing %$is d!+g)'

    8' Info!m %$e pa%ien% %o!epo!% so!e %$!oa%, fe&e!,

    !as$, i%c$ing, eig$% gain,selling in anles o!

    finge!s1 c$anges in &ision'

  • 8/12/2019 Drug Study for Sale

    2/5

    Generic

    Name

    Brand

    Name

    Mechanism of

    Action

    Indications Contraindications Adverse Effects Nursing Consideration

    $.Cef+!oximeAxe%il

    Classification:

    Anti-infective

    Dosage: 9:"

    mgre!uenc":

    ; ANS?

    Cef+!oximeAxe%il

    (Cef%in@.'O')

    Second-gene!a%ion

    cep$alospo!in%$a% in$ibi%s

    cell-allsyn%$esis,

    p!omo%ing

    osmo%icins%abili%y1

    +s+allybac%e!icidal'

    .$a!yngi%is,%onsilli%is,

    infec%ions of %$e+!ina!y and loe!

    !espi!a%o!y %!ac%s,and sin and sin-

    s%!+c%+!e

    infec%ionsBncomplica%ed

    B?Is

    O%i%is /edia

    .$a!yngi%is and

    ?onsilli%is

    5a!ly ymeDisease

    Seconda!ybac%e!ial infec%ion

    of ac+%e b!onc$i%is

    Bncomplica%ed

    gono!!$ea'

    Con%!aindica%ed inpa%ien%s

    $ype!sensi%i&e %od!+g'

    Bse ca+%io+sly in

    pa%ien%s

    $ype!sensi%i&e %openicillin beca+se of

    possibili%y of c!oss-sensi%i&i%y i%$ o%$e!

    be%a-lac%am

    an%ibio%ics'

    Bse i%$ ca+%ion inb!eas%-feeding

    omen and inpa%ien%s i%$ $is%o!y

    of coli%is o! !enal

    s+fficiency'

    C>6 p$lebi%is,%$!ombop$lebi%is

    I6

    pse+domemb!ano+scoli%is, na+sea,

    ano!exia, &omi%ing,

    dia!!$ea

    0ema%ologic6%!ansien%

    ne+%!openia,

    eosinop$ilia,$emoly%ic anemia,

    ?$!ombocy%openia

    Sin6mac+lopap+la! and

    e!y%$ema%o+s

    !as$es, +!%ica!ia,pain, ind+!a%ion,

    s%e!ile abscesses,%empe!a%+!e

    ele&a%ion'

    O%$e!6

    $ype!sensi%i&i%y!eac%ions, se!+m

    sicness,anap$ylaxis'

    2' #efo!e adminis%e!ing,mae s+!e pa%ien% is no%

    alle!gic %o penicillins o!cep$alospo!ins'

    3' Abso!p%ion of cef+!oxime

    axe%il is en$anced by food'

    8' Cef+!oxime axe%il %able%s

    may be c!+s$ed if salloingis a diffic+l%y'

    :' ?ae medica%ion asp!esc!ibed, e&en af%e! feeling

    be%%e!'

    E' ?ae o!al fo!m i%$ food'

    9' If s+spension is being +sed,

    s$ae %$e con%aine! ellbefo!e meas+!ing dose'

  • 8/12/2019 Drug Study for Sale

    3/5

    Generic

    Name

    Brand

    Name

    Mechanism of

    Action

    Indication Contraindications Adverse

    Effects

    Nursing Consideration

    %..AAC5

    ?A/O

    Classificati

    on: An%i-

    py!e%ic4Analgesic

    orm:

    ?able%s

    Dosage:

    :"" mg

    re!uenc":F 8 4 .N

    #oute:

    O!al

    #iogesic ?$o+g$% %o

    p!od+ceanalgesia by

    blocing painimp+lses by

    in$ibi%ing

    syn%$esis ofp!os%aglandin

    in %$e CNS o!of o%$e!

    s+bs%ances %$a%

    sensi%ize pain!ecep%o!s %o

    s%im+la%ion'?$e d!+g may

    !elie&e fe&e!%$!o+g$ cen%!al

    ac%ion in %$e

    $ypo%$alamic$ea%-!eg+la%ing

    cen%e!'

    G/ild pain

    o! e&e!

    GCon%!aindica%ed in

    pa%ien% $ype!sensi%i&e %od!+g'

    GBse ca+%io+sly inpa%ien% i%$ long %e!m

    alco$ol +se beca+se

    %$e!ape+%ic doses ca+se$apa%o%oxici%y in %$is

    pa%ien%s'

    G0ema%ologic6

    $emoly%icanemia,

    ne+%!openia,le+copenia,

    pancy%openia'

    G0epa%ic6Ha+ndice

    G/e%abolic6$ypoglycemia

    GSin6 !as$,

    +!%ica!ia'

    *' Ad&ise pa%ien% %$a% d!+g is only

    fo! s$o!% %e!m +se and %o cons+l%p!esc!ibe! if gi&ing %o c$ild!en fo!

    longe! %$an fi&e days o! ad+l% fo!longe! %$an %en days'

    2' ?ell pa%ien% no% %o +se fo! ma!edfe&e!( %empe!a%+!e $ig$e! %$an *"3'*

    @3': C), fe&e! pe!sis%ing longe!%$an %$!ee days, o! !ec+!!en% fe&e!

    +nless di!ec%ed by p!esc!ibe!'

    3' Ale!%6 Ja!n pa%ien% %$a% $ig$

    doses o! +ns+pe!&ised long %e!m +secan ca+se li&e! damage'

    8' ?ell %o b!eas% feeding oman %$a%

    ace%aminop$en appea!s in b!eas%

    mil lo le&els ( less %$an *K dose)'D!+g may be +sed safely if %$e!apy

    is s$o!% %e!m and doesnL% exceed!ecommended doses'

  • 8/12/2019 Drug Study for Sale

    4/5

    Generic

    Name

    Brand

    Name

    Mechanism of

    Action

    Indication Contraindications Adverse Effects Nursing Consideration

    &. 5!dos%ein

    Classificati

    on:m+coly%ic

    agen%

    orm:

    Caps+le

    Dosage:

    3"" mg

    re!uenc":

    #ID

    #oute:O!al

    Me!%in Ac%s as a p!od!+g

    and i%s me%aboli%esa!e mainly

    !esponsible fo!m+coly%ic ac%i&i%y'

    I% o!s by $elping%o b!ea don

    m+c+s sec!e%ions'

    ?!ea%men% of

    ac+%e andc$!onic

    b!onc$op+lmona!y

    disease

    Con%!aindica%ed in

    pa%ien%s i%$ pep%ic+lce!, .!egnancy and

    $ype!sensi%i&i%y'

    S%omac$ pain

    Na+sea

    >omi%ing

    loose s%ools spasmodic

    coli%is

    $eadac$e'

    *' #efo!e gi&ing %$e medica%ionmae s+!e %$a% %$e clien% is no%

    p!egnan% and non lac%a%ing'

    2' Info!m %$e pa%ien% %$a% i% canbe %aen i%$ o! i%$o+% food'

    3' As %$e pa%ien% %o no%ify anyof %$e $eal%$ca!e %eam if %$e $e

    feels na+sea, &omi%ing,abdominal pain o! %a!!y s%ools

    occ+!'

    8' 5mp$asize %$e impo!%ance

    follo +p exams

  • 8/12/2019 Drug Study for Sale

    5/5

    Generic

    Name

    Brand

    Name

    Mechanism of

    Action

    Indication Contraindications Adverse Effects Nursing Consideration

    '..!ednisone

    Classificatio

    n:Co!%icos%e!oid(in%e!media%eac%ing),l+coco!%icoid, 0o!mone

    orm:?able%

    Dosage:

    : mgre!uenc":

    ?ID

    #oute:

    O!al

    Del%asone I% dec!easesinflamma%ion bys+pp!ession ofmig!a%ion of

    polymo!p$on+clea! le+ocy%es and

    !e&e!sal ofinc!eased capilla!y

    pe!meabili%y1s+pp!esses %$e

    imm+ne sys%em by!ed+cing ac%i&i%y

    and &ol of %$elymp$a%ic sys%em1s+pp!esses ad!enal

    f+nc%ion a% $ig$doses' Indica%ionsand dosage a!esame as %$ose fo!

    p!ednisolone'

    S$o!%-%e!m

    managemen% of

    &a!io+s

    inflamma%o!y and

    alle!gic diso!de!s,s+c$ as

    !$e+ma%oid

    a!%$!i%is, collagen

    diseases (eg,

    S5),

    de!ma%ologic

    diseases (eg,

    pemp$ig+s), s%a%+s

    as%$ma%ic+s, and

    a+%oimm+nediso!de!s'

    eplacemen%

    %$e!apy in ad!enal

    co!%ical

    ins+fficiency

    0ype!sensi%i&i%y,

    se!io+s infec%ions

    (excep% %+be!c+lo+s

    meningi%is), &a!icella,

    sys%emic f+ngalinfec%ions'

    Insomnia,ne!&o+sness,inc!eased appe%i%e,indiges%ion,

    dizziness4lig$%$eadedness, $eadac$e,

    $i!s+%ism,$ypopigmen%a%ion,

    diabe%es melli%+s,gl+cose in%ole!ance,

    $ype!glycaemia,a!%$!algia, ca%a!ac%s,

    gla+coma, epis%axis,diap$o!esis,C+s$ings synd!ome,

    edema, f!ac%+!es,$all+cina%ions,$ype!%ension, m+scle-as%ing,os%eopo!osis,

    panc!ea%i%is, pi%+i%a!y-ad!enal axiss+pp!ession, seiz+!es'

    *' Info!m %$e p%' %o do no% s%op%aing %$e d!+g i%$o+%

    cons+l%ing yo+! $eal%$ ca!ep!o&ide!1

    2' Info!m %$e p%' %o A&oid

    expos+!e %o infec%ions'

    3' Info!m %$e p%' %o epo!%

    +n+s+al eig$% gain, sellingof %$e ex%!emi%ies, m+scle

    eaness, blac o! %a!!y s%ools,

    fe&e!, p!olonged so!e %$!oa%,colds o! o%$e! infec%ions,

    o!sening of %$e diso!de! fo!$ic$ %$e d!+g is being %aen'