drug study for sale
TRANSCRIPT
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8/12/2019 Drug Study for Sale
1/5
Generic
name
Brand
Name
Mechanism of
Action
Indications Contra-indications Adverse Effects Nursing Consideration
1.Celecoxib
Classification
:NSAID,
Analgesic(nonopioid),
Specific
COX-2enzyme
bloce!
Dosage:
2"" mgre!uenc":
#ID p!n fopain
#oute:
O!al
Celeb!ex Celecoxib $asCOX-2 specific
in$ibi%o!yac%i&i%y' I%
in$ibi%s %$econ&e!sion of
a!ac$idonic
acid %op!os%aglandins
$ile $a&ingno effec% on %$e
fo!ma%ion of
p!os%aglandins%$a% media%e
%$e no!mal$omeos%asis in
%$e I %!ac%,idneys and
pla%ele%s
ca%alyzed byCOX-*'
Ac+%e andlong-%e!m
%!ea%men% ofsigns and
symp%oms of!$e+ma%oid
a!%$!i%is and
os%eoa!%$!i%is
ed+c%ion of
%$e n+mbe! ofcolo!ec%al
polyps infamilial
adenoma%o+spolyposis
(A.)
/anagemen%
of ac+%e pain
0ype!sensi%i&i%yincl+ding %$ose in
$om a%%acs ofangioedema, !$ini%is
and +!%ica!ia $a&ebeen p!ecipi%a%ed by
aspi!in, NSAIDs o!
s+lfonamides'Se&e!e $epa%ic
impai!men%1 se&e!e$ea!% fail+!e1
inflamma%o!y boel
disease1 pep%ic +lce!1!enal impai!men%
(C!Cl 3" ml4min)1p!egnancy and
lac%a%ion'
Abdominal pain
Dia!!$ea
Na+sea
5dema Dizziness
0eadac$e
Insomnia
+ppe! !espi!a%o!y
%!ac% infec%ions
!as$
.o%en%ially a%al6
exfolia%i&e
de!ma%i%is
S%e&ens-7o$nson
synd!om
%oxic epide!mal
nec!olysis'
*' Info!m %$e pa%ien% %o %ae
d!+g i%$ food o! meals ifI +pse% occ+!s'
2' Info!m %$e pa%ien% %o %ae
only %$e p!esc!ibeddosage1 do no% inc!ease
dosage'
3' Info!m %$e pa%ien% %$a%
$e4s$e may expe!ience%$ese side effec%s6
Dizziness, d!osiness(a&oid d!i&ing o! %$e +se
of dange!o+s mac$ine!y$ile %aing %$is d!+g)'
8' Info!m %$e pa%ien% %o!epo!% so!e %$!oa%, fe&e!,
!as$, i%c$ing, eig$% gain,selling in anles o!
finge!s1 c$anges in &ision'
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8/12/2019 Drug Study for Sale
2/5
Generic
Name
Brand
Name
Mechanism of
Action
Indications Contraindications Adverse Effects Nursing Consideration
$.Cef+!oximeAxe%il
Classification:
Anti-infective
Dosage: 9:"
mgre!uenc":
; ANS?
Cef+!oximeAxe%il
(Cef%in@.'O')
Second-gene!a%ion
cep$alospo!in%$a% in$ibi%s
cell-allsyn%$esis,
p!omo%ing
osmo%icins%abili%y1
+s+allybac%e!icidal'
.$a!yngi%is,%onsilli%is,
infec%ions of %$e+!ina!y and loe!
!espi!a%o!y %!ac%s,and sin and sin-
s%!+c%+!e
infec%ionsBncomplica%ed
B?Is
O%i%is /edia
.$a!yngi%is and
?onsilli%is
5a!ly ymeDisease
Seconda!ybac%e!ial infec%ion
of ac+%e b!onc$i%is
Bncomplica%ed
gono!!$ea'
Con%!aindica%ed inpa%ien%s
$ype!sensi%i&e %od!+g'
Bse ca+%io+sly in
pa%ien%s
$ype!sensi%i&e %openicillin beca+se of
possibili%y of c!oss-sensi%i&i%y i%$ o%$e!
be%a-lac%am
an%ibio%ics'
Bse i%$ ca+%ion inb!eas%-feeding
omen and inpa%ien%s i%$ $is%o!y
of coli%is o! !enal
s+fficiency'
C>6 p$lebi%is,%$!ombop$lebi%is
I6
pse+domemb!ano+scoli%is, na+sea,
ano!exia, &omi%ing,
dia!!$ea
0ema%ologic6%!ansien%
ne+%!openia,
eosinop$ilia,$emoly%ic anemia,
?$!ombocy%openia
Sin6mac+lopap+la! and
e!y%$ema%o+s
!as$es, +!%ica!ia,pain, ind+!a%ion,
s%e!ile abscesses,%empe!a%+!e
ele&a%ion'
O%$e!6
$ype!sensi%i&i%y!eac%ions, se!+m
sicness,anap$ylaxis'
2' #efo!e adminis%e!ing,mae s+!e pa%ien% is no%
alle!gic %o penicillins o!cep$alospo!ins'
3' Abso!p%ion of cef+!oxime
axe%il is en$anced by food'
8' Cef+!oxime axe%il %able%s
may be c!+s$ed if salloingis a diffic+l%y'
:' ?ae medica%ion asp!esc!ibed, e&en af%e! feeling
be%%e!'
E' ?ae o!al fo!m i%$ food'
9' If s+spension is being +sed,
s$ae %$e con%aine! ellbefo!e meas+!ing dose'
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8/12/2019 Drug Study for Sale
3/5
Generic
Name
Brand
Name
Mechanism of
Action
Indication Contraindications Adverse
Effects
Nursing Consideration
%..AAC5
?A/O
Classificati
on: An%i-
py!e%ic4Analgesic
orm:
?able%s
Dosage:
:"" mg
re!uenc":F 8 4 .N
#oute:
O!al
#iogesic ?$o+g$% %o
p!od+ceanalgesia by
blocing painimp+lses by
in$ibi%ing
syn%$esis ofp!os%aglandin
in %$e CNS o!of o%$e!
s+bs%ances %$a%
sensi%ize pain!ecep%o!s %o
s%im+la%ion'?$e d!+g may
!elie&e fe&e!%$!o+g$ cen%!al
ac%ion in %$e
$ypo%$alamic$ea%-!eg+la%ing
cen%e!'
G/ild pain
o! e&e!
GCon%!aindica%ed in
pa%ien% $ype!sensi%i&e %od!+g'
GBse ca+%io+sly inpa%ien% i%$ long %e!m
alco$ol +se beca+se
%$e!ape+%ic doses ca+se$apa%o%oxici%y in %$is
pa%ien%s'
G0ema%ologic6
$emoly%icanemia,
ne+%!openia,le+copenia,
pancy%openia'
G0epa%ic6Ha+ndice
G/e%abolic6$ypoglycemia
GSin6 !as$,
+!%ica!ia'
*' Ad&ise pa%ien% %$a% d!+g is only
fo! s$o!% %e!m +se and %o cons+l%p!esc!ibe! if gi&ing %o c$ild!en fo!
longe! %$an fi&e days o! ad+l% fo!longe! %$an %en days'
2' ?ell pa%ien% no% %o +se fo! ma!edfe&e!( %empe!a%+!e $ig$e! %$an *"3'*
@3': C), fe&e! pe!sis%ing longe!%$an %$!ee days, o! !ec+!!en% fe&e!
+nless di!ec%ed by p!esc!ibe!'
3' Ale!%6 Ja!n pa%ien% %$a% $ig$
doses o! +ns+pe!&ised long %e!m +secan ca+se li&e! damage'
8' ?ell %o b!eas% feeding oman %$a%
ace%aminop$en appea!s in b!eas%
mil lo le&els ( less %$an *K dose)'D!+g may be +sed safely if %$e!apy
is s$o!% %e!m and doesnL% exceed!ecommended doses'
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8/12/2019 Drug Study for Sale
4/5
Generic
Name
Brand
Name
Mechanism of
Action
Indication Contraindications Adverse Effects Nursing Consideration
&. 5!dos%ein
Classificati
on:m+coly%ic
agen%
orm:
Caps+le
Dosage:
3"" mg
re!uenc":
#ID
#oute:O!al
Me!%in Ac%s as a p!od!+g
and i%s me%aboli%esa!e mainly
!esponsible fo!m+coly%ic ac%i&i%y'
I% o!s by $elping%o b!ea don
m+c+s sec!e%ions'
?!ea%men% of
ac+%e andc$!onic
b!onc$op+lmona!y
disease
Con%!aindica%ed in
pa%ien%s i%$ pep%ic+lce!, .!egnancy and
$ype!sensi%i&i%y'
S%omac$ pain
Na+sea
>omi%ing
loose s%ools spasmodic
coli%is
$eadac$e'
*' #efo!e gi&ing %$e medica%ionmae s+!e %$a% %$e clien% is no%
p!egnan% and non lac%a%ing'
2' Info!m %$e pa%ien% %$a% i% canbe %aen i%$ o! i%$o+% food'
3' As %$e pa%ien% %o no%ify anyof %$e $eal%$ca!e %eam if %$e $e
feels na+sea, &omi%ing,abdominal pain o! %a!!y s%ools
occ+!'
8' 5mp$asize %$e impo!%ance
follo +p exams
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8/12/2019 Drug Study for Sale
5/5
Generic
Name
Brand
Name
Mechanism of
Action
Indication Contraindications Adverse Effects Nursing Consideration
'..!ednisone
Classificatio
n:Co!%icos%e!oid(in%e!media%eac%ing),l+coco!%icoid, 0o!mone
orm:?able%
Dosage:
: mgre!uenc":
?ID
#oute:
O!al
Del%asone I% dec!easesinflamma%ion bys+pp!ession ofmig!a%ion of
polymo!p$on+clea! le+ocy%es and
!e&e!sal ofinc!eased capilla!y
pe!meabili%y1s+pp!esses %$e
imm+ne sys%em by!ed+cing ac%i&i%y
and &ol of %$elymp$a%ic sys%em1s+pp!esses ad!enal
f+nc%ion a% $ig$doses' Indica%ionsand dosage a!esame as %$ose fo!
p!ednisolone'
S$o!%-%e!m
managemen% of
&a!io+s
inflamma%o!y and
alle!gic diso!de!s,s+c$ as
!$e+ma%oid
a!%$!i%is, collagen
diseases (eg,
S5),
de!ma%ologic
diseases (eg,
pemp$ig+s), s%a%+s
as%$ma%ic+s, and
a+%oimm+nediso!de!s'
eplacemen%
%$e!apy in ad!enal
co!%ical
ins+fficiency
0ype!sensi%i&i%y,
se!io+s infec%ions
(excep% %+be!c+lo+s
meningi%is), &a!icella,
sys%emic f+ngalinfec%ions'
Insomnia,ne!&o+sness,inc!eased appe%i%e,indiges%ion,
dizziness4lig$%$eadedness, $eadac$e,
$i!s+%ism,$ypopigmen%a%ion,
diabe%es melli%+s,gl+cose in%ole!ance,
$ype!glycaemia,a!%$!algia, ca%a!ac%s,
gla+coma, epis%axis,diap$o!esis,C+s$ings synd!ome,
edema, f!ac%+!es,$all+cina%ions,$ype!%ension, m+scle-as%ing,os%eopo!osis,
panc!ea%i%is, pi%+i%a!y-ad!enal axiss+pp!ession, seiz+!es'
*' Info!m %$e p%' %o do no% s%op%aing %$e d!+g i%$o+%
cons+l%ing yo+! $eal%$ ca!ep!o&ide!1
2' Info!m %$e p%' %o A&oid
expos+!e %o infec%ions'
3' Info!m %$e p%' %o epo!%
+n+s+al eig$% gain, sellingof %$e ex%!emi%ies, m+scle
eaness, blac o! %a!!y s%ools,
fe&e!, p!olonged so!e %$!oa%,colds o! o%$e! infec%ions,
o!sening of %$e diso!de! fo!$ic$ %$e d!+g is being %aen'