DRUG ACTING ON THE RESPIRATORY SYSTEM

BRONCHODILATORS

• Relax the smooth muscle of the tracheobronchial tree.• This allows an increase in the opening of the bronchioles

and alveolar ducts, which decreases the resistance to airflow into the alveolar sacs

• Asthma and bronchitis cause reversible obstruction of the airways.

• The airway constriction associated with emphysema is somewhat reversible depending on the severity and duration of the disease.

• The primary bronchodilators used in the treatment of airway-obstructive diseases include beta-adrenergic agents \

Albuterol sulfate (salbutamol sulfate)

Action • Relaxes smooth muscle by stimulation beta2

receptor, thereby causing bronchodilation and vasodilation.

indication

• To prevent and relieve broncho spasm in patient with reversible obstructive airway disease

Side effects to expect

• Gastrointestinal upset • Nausea and vomiting

expectorant

Example • Robitussin• Potassium iodide

action

• Acts by enhancing the output of respiratory tract fluid. The increase flow of secretion, decreases mucus viscosity and promotes cilliary action. Non productive cough, as well as to remove mucus plugs from respiratory.

Side effects

• Gastrointestinal upset• Nausea and vomiting• Development on side effect are rare

antitussive

Action/uses• Action suppressant, act by suppressing the

cough center in the brain.• Are use when the patient has bothersome dry,

hacking, non productive cough.• Not stop the cough frequently but decrease the

frequency of cough and suppress the severe spasm that prevent adequate rest at night.

examples

• Codiene• Dextromethopan• diphenhydramide

Side effects

• Drowsiness• constipation