dr. yingtian pan’s lab unjoo lee. about him he is an associate professor

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Dr. Yingtian Pan’s Lab Unjoo Lee

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Page 1: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

Dr. Yingtian Pan’s Lab

Unjoo Lee

Page 2: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About him He is an associate Professor 

http://www.bme.sunysb.edu/bme/people/faculty/y_pan.html

Page 3: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Dr. Pan is interested in early-stage

epithelial cancer detection, diagnosis of cartilage injury and repair, and assessment of engineering tissue growth. In addition, his lab studies skin dehydration, geriatric incontinence, fluorescence imaging and light microscopy.

Page 4: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Optical coherence tomography (OCT)

a new noninvasive optical diagnostic technique that provides depth-resolved images of tissues with resolution of about 2-10 µm at depths of up to several mm.

This technique was introduced in 1991 to perform tomographic imaging of the human eye by Fujimoto's group at MIT.

The basic principle of the OCT is to detect backscattered photons from a tissue of interest within a coherence length of the source by using a two-beam interferometer.

Page 5: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Optical coherence tomography (OCT)

OCT imaging is somewhat analogous to ultrasound B-mode imaging except that it uses light, not sound.

Briefly, light from a broadband source (a laser with low coherence) is aimed at objects to be imaged using a beam splitter.

Light scattered from the tissue is combined with light returned from the reference arm, and a photodiode detects the resulting interferometric signal.

Page 6: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Optical coherence tomography (OCT)

OCT imaging is somewhat analogous to ultrasound B-mode imaging except that it uses light, not sound.

Interferometric signals can be formed only when the optical path length in the sample arm matches the reference arm length within coherence length of the source.

By gathering interference data at points across the surface, cross-sectional 2D and 3D images can be formed in real time with resolution of about 2-10 µm at depths up to several millimeters, depending on the tissue optical properties.

Page 7: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Optical coherence tomography (OCT)

Time domain OCT

Page 8: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Optical coherence tomography (OCT)

Fourier domain OCTusing a broadband laser source (typical FWHM > 75 nm) with a grating and a photodiode array in the detection arm

Page 9: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Optical coherence tomography (OCT)

Swept source OCT

using a rapidly tunable, narrow-linewidth laser source over a broad optical bandwidth with a single photodiode in the detection arm.

Page 10: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Laser scanning endoscope

Page 11: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Laser scanning endoscope

Page 12: Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

About his research Laser scanning endoscope

Color SFE images taken at 10 Hz frame rate, (top-left) teeth of the author, (top-right) scar on skin of the author, (bottom-left) live flower, and (bottom-right) dried sheep lung. All 500-line images are generated from a 250 spiral pattern.