Dr. Mary Ann Osley –Professor: Dr. Osley’slaboratory is focused on therole of chromatin in geneexpression, DNA replication,and DNA repair as cells enter

and exit quiescence. Her research usesbudding yeast, Saccharomyces cerevisiae,to study these cellular processes.

PMID: 28122508

Dr. Vojo Deretic – Chair: Dr.Deretic's main contributions toscience come from studies byhis team on the role ofautophagy in infection and

immunity. Autophagy, a cytoplasmicpathway for the removal of damaged orsurplus organelles, has been previouslyimplicated in cancer, neurodegeneration,development, and aging. Dr. Deretic'sgroup is one of those that made thediscovery that autophagic degradation is amajor effector and a regulator of innate andadaptive immune mechanisms.

PMID: 19527881

Dr. Robert Rubin– Professor:Dr. Rubin’s lab explores T celltolerance and autoimmunity, Tcell development in thethymus, systemic and drug-induced lupus, & autoantibody

biosensors. Dr. Rubin’s laboratory alsostudies the cellular and molecular basis forthe capacity of lupus-inducing drugs todisrupt central T cell tolerance.

Dr. David Peabody –Professor: Dr. Peabody wastrained at Stanford Universityin the laboratory of Paul Berg(Nobel Prize, 1980) and hasbeen associated with UNM

since 1984. For a number of years hisgroup studied RNA viruses of bacteria asmodel systems to understand generegulation. In recent years his group hasfocused on adapting the virus-like particlesof these bacteriophages as platforms forvaccine discovery and delivery.

PMID: 26147502

Dr. Bryce Chackerian –Professor: Dr. Chackerian’slaboratory is focused onvaccine development. Inparticular, they use virusparticles as platforms for the

Display of antigens. Dr. Chackerian'slaboratory has demonstrated that antigensthat are normally poorly immunogenic canbe made highly immunogenic by displayingthem in a multivalent, repetitive format onthe surface of virus particles -- essentiallyusing viruses as platforms for vaccines.

PMID: 27389630

Dr. Ellen Beswick–Associate Professor: Dr.Beswick’s laboratory isinterested in understandingthe relationship betweenchronic inflammation and

gastrointestinal (GI) cancers, developingnovel immuno-therapeutics for GI cancer, Tcell immunology in the GI tract, Treg andTh17 differentiation and responses in GIcancers, Helicobacter pylori, InflammatoryBowel Disease.

PMID: 26061815

Isotype control anti-G-CSF antibody

Dr. Judy Cannon – AssociateProfessor: Dr. Cannon’sresearch is focused on T cellmigration, T cell signaling, andleukemia cell migration usingin vivo imaging. Dr. Cannon’s

Group has visualized T cells moving inintact lymph nodes and lungs combinedwith computational modeling to betterunderstand immune responses.

PMID: 23727894

Dr. Kiran Bhaskar –Assistant Professor: Dr.Bhaskar’s research is relatedto understanding the role ofneuroinflammation inAlzheimer’s disease (AD).

Importantly, his lab investigates theinflammation cell-autonomous to microgliain driving AD-related pathologies, neuro-degeneration and cognitive impairment invarious models of AD.

Dr. Michael Mandell – AssistantProfessor: Dr. Mandell’s research isfocused on the autophagic targetingof HIV-1 by members of TRIM familyof proteins (TRIMs). Dr. Mandell’slaboratory has determined that

TRIMs link autophagy induction with targetspecificity. These dual functions can respond toHIV infection promoting the clearance of viralcomponents from the cell. The current focus ofthe lab is to uncover how TRIMs and autophagymodulate HIV-induced immune signaling. PMID: 25127057

Dr. Kathryn Frietze – ResearchAssistant Professor: Dr. Frietze’sresearch aims to develop newtechnologies to assess antibodyspecificity and responsiveness ininfectious and chronic diseases.

Dr. Frietze’s laboratory is also interested intranslating the understanding of antibodyresponses into targeted therapeutic orprophylactic interventions for various infectiousand chronic diseases.

Dr. Paulus Mrass – ResearchAssistant Professor : Dr. Mrass’sresearch is focused on directvisualization and analysis of thebehavior of CD8+ effector T cellsat the site of inflammation

using cutting-edge imaging technology. The labalso focused on direct in vivo visualization of Tcell migration and interaction with otherimmune cells during sterile lung inflammationor infection with influenza virus.PMID: 27039982

Dr. Xuexian Yang –Associate Professor: Dr.Yang’s laboratory investigatesthe regulation and function of Thelper (Th17 and Th2) cells ininflammatory and autoimmune

diseases, including neuro-inflammation,allergy, IBD and colon cancer. Dr. Yang’sgroup is also interested in transcriptionalcontrol in T cells and cytokine signalingduring adaptive immunity.

Dr. Michelle Ozbun –Professor: Dr. Ozbun’s labstudies the cellular and viralmechanisms that regulate thelife cycles of papillomaviruses(PVs), aiming to understand

the delicate virus-cell interactions that canbecome unbalanced, leading tomalignancies. Three areas of researchinterests are understanding: a) strategiesfor PV infection and persistence; b) PVand host interactions; c) the mechanismsof HPV-induced malignant transformation.