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RAJIVGANDHI UNIVERSITY OF HEALTH SCIENCES, KARNATAKA.
PROFORMA FOR REGISTRATION OF SUBJECT FOR
DISSERTATION
1. Name of the candidate and address Ms. G. Rekha
M.Sc Nursing I year,
Dr.Syamala Reddy College of Nursing,
No. 111/1, SGR Main Road, Munnekolala,
Marathahalli - Post,
Bangalore-560037.
2. Name of the Institution Dr. Syamala Reddy College of Nursing.
3. Course of study and subject M.Sc Nursing I year.
Community Health Nursing
4. Date of admission to course June – 2010
5. Title of the topic A descriptive study on assessment of
compliance among diabetic clients
regarding diabetic management in
Kadugudi PHC at Bangalore.
1
2
6. BRIEF RESUME OF INTENTED WORK:
INTRODUCTION :-
“This is the day when people reciprocally offer, and receive, the kindest and
the warmest wishes, though, in general, without meaning them on one side, or
believing them on the other. They are formed by the head, in compliance with
custom, though disavowed by the heart, in consequence of nature”
- Philip Dormer Stanhope
“He in a few minutes ravished this fair creature, or at least would have ravished her, if
she had not, by a timely compliance, prevented him”
- Hendry Fielding
The pancreas is a long, slender gland lying behind the stomach and in front of the
first and second lumbar vertebrae. The pancreas has both exocrine and endocrine functions.
The exocrine function of the pancreas contributes to the process of digestion. Endocrine
function occurs in the islets of langerhans, whose beta cells secrete insulin, alpha cells
secrete glucagon; delta cells secrete somstostatin; and F cells secrete pancreatic
polypeptide1.
Insulin is the principal regulator of the metabolism and storage of ingested
carbohydrates, fats and proteins. Insulin facilitates glucose transport across cell membranes
in most tissues. When the blood glucose rises, insulin is released from the pancreas to
normalize the glucose level1.
Diabetes is an iceberg disease. It is a complex condition with global health
consequences. The term “diabetes mellitus” is derived from the Greek word, “diabetes”
3
means “to go through” or a siphon and the word “mellitus” is derived from the Latin word
“mel” meaning honey describing the sweet odour of urine2.
Diabetes Mellitus is a chronic multisystem disease related to abnormal insulin
production, impaired insulin utilization, or both. Diabetes Mellitus is a serious health
problem throughout the world and its prevalence is increasing rapidly1.
According to WHO (1994) diabetes mellitus is characterized by hyperglycemia and
disturbance of the carbohydrate, fat and protein metabolism that is associated with the
absolute or relative deficiencies of insulin action or secretion3.
The American Diabetes Association uses the acronyms “DIABETES” and
“CAUTION” help to identify the warning signs of diabetes.
Drowsiness, Itching, A family history of diabetes, Blurred vision, Excessive Weight,
Tingling numbness or pain in extremities, Easy fatigue, Skin infection, slow healing of cuts
and scratches especially on the feet.
Other signs are, Constant urination, Abnormal thirst, Unusual hunger, The rapid loss of
weight, Irritability, Obvious weakness and fatigue, Nausea and vomiting4.
India has now been declared by WHO as the diabetes capital of the world. The
choice of treatment and compliance is important for the metabolic control to be achieved by
the patients. While diet, exercise and oral drugs are useful in controlling diabetes in many
patients, it is now recognized that a large number of Type 2 diabetic patients require insulin
therapy5
India has the world’s largest population of people with diabetes- 50.8 million as
per latest statistics of International Diabetes federation. Diabetes is the leading cause of
adult blindness, end-stage renal disease and non traumatic lower limb amputations. It is also
4
a major contributing factor for heart disease and stroke. Adults with diabetes have heart
disease death rates two to four times higher than adults without diabetes. The risk for stroke
is also two to four times higher among people with diabetes. In addition, about 73% of
adults with diabetes have hypertension6
A study was conducted for one and half years by the Manipal Hospital Bangalore with
diabetes and Hypertension patients and it revealed that almost 40% to 60% of patients had
both the conditions. And 50% had at least two risk factors like high cholesterol or
overweight. About 20% to 30% were smokers. Compliance became a major issue.
Explaining the lack of compliance and integrated diabetes support- Earlier patients used to
come with a predisposed idea that if they are asked to take insulin, they would refuse and try
to avoid it for at least a year. Hypertension did not receive as much attention as diabetes
mainly because “diabetes is a silent killer and the onset is very early” 6.
The latest Compliance is on drug how well a patient follows the instructions for taking
his/her medication. Poor compliance is a leading cause of failed medical treatment and drug-
resistant conditions. Diabetes is the fourth leading cause of death in developed world; it
affects the blood vessels, nerves, heart, kidneys and eyes7.
6.1 NEED FOR STUDY :-
One of the challenges faced by the modern world is diabetes mellitus. Diabetes
mellitus has been recognized as a chronic condition that challenges every aspect of
personal, emotional, social, physical, psychological and spiritual life of an individual. It is
the leading cause of non traumatic amputations and blindness8.
5
Diabetes is a chronic disease that occurs when the pancreas doesn’t produce enough
insulin or alternatively. Diabetes is currently considered an epidemic disease that is largely
preventable and treatable through diet, exercise and life style changes. Diabetes is among
the leading causes of kidney failure and 10-20% of people with diabetes die of kidney
failure. Diabetes increases the risk of heart diseases and stroke; 50% of people with
diabetes die of cardio vascular diseases9.
According to the American Diabetes association, the prevalence of Diabetes
mellitus has increased dramatically during the past few decades, and it is expected to
increase even more in the future. In the United States an estimated 20.8 million people, or
7% of the population have diabetes mellitus and more than 2 million Canadians have
diabetes. Over 6 million people with diabetes mellitus are not diagnosed, and these
individuals are unaware that they have the diabetes. Diabetes mellitus is the fifth leading
cause of the death in the United States, but it is under reported10.
India’s diabetic population is around 51 million now and is expected to touch 87
million by 2030. Every minute, six people die due to diabetes and its complications.
Despite an adult prevalence rate of 6.2%, only 6-7 million people are treated. The
increasing incidence of multi-organ complications arising from diabetes has become a
major cause for concern. Complications include cardiovascular diseases, diabetic
neuropathy, diabetic nephropathy, stroke, blindness and limb amputation6.
While incidence if Type1 diabetes is increasing, Type 2 is also being found in
younger age groups. The problems are lifestyle- related. Infact, nutrition and proper diet
should start at the fetal stage, because most development happens then6. In regard with
6
diabetes control, an observational study to collect information on prevalence of diagnosed
and undiagnosed diabetes and hypertension cases in outpatient clinics in major Indian
cities and to understand the extent of risk factors among these patients. Also now mass
screening program for diabetes and hypertension has been initiated by TamilNadu
Government11.
According to WHO, in India 31 million people are affected by diabetes which is
highest in the world (2002) and 5% of Bangaloreans have diabetes and about 30,000 of
these develop foot problem annually12. According to the new Indian press (2004)
Hyderabad and Chennai is the diabetes capital of India. Hyderabad tops the metropolitan
cities in the prevalence of diabetes (16.6%) followed by Chennai (23.5%), Bangalore
(12.4%) Kolkata (11.6%) and Mumbai (9.3%). The most important aspect of diabetes in
occurrence of complications that increases the cost of management13.
There are approximately 3.5 crore diabetic clients in India, and this figure is
expected to increase up to 5.2 crore by 2025. Every fifth client visiting a consulting
physician is a diabetic and every seventh client visiting a family physician is a diabetic14.
In 2005, an estimated 1.1 million people died from diabetes. Almost 80% of the
deaths occur in low and middle income countries with half of the deaths occurring in
people under the age of 70 years. WHO projects that deaths due to diabetes will be more
than 50% in the next ten years without appropriate measures. Deaths due to diabetes are
projected to increase by over 80% in upper middle income countries between 2006-2015.
In another estimate by International Diabetes Federation (IDF) 200 million people around
world have diabetes by 2025 and it is expected to increase to 333 million15.
7
Self care is the practice of activities that individuals initiate and perform on their
own behalf in maintaining life, health and well being. Self care in diabetes is crucial. It has
been claimed that as much as 98% of diabetes care is self care. Self-care in diabetes falls
mostly on the patients and their families. It is essential that individuals with diabetes
adhere to self care and to prevent the complications associated with diabetes16.
Diabetes self management education is the process of teaching individuals to
manage their diabetes and has been considered an important part of the clinical
management of individuals. The goals of the self management education are to optimize
metabolic control, prevent acute and chronic complications and optimize quality of life,
while keeping costs acceptable17.
A cross sectional survey was conducted in a resettlement colony of Chandigarh
about knowledge and practices regarding diet, hygiene, care of foot, wound, complication
of diabetes and medication. This study has concluded that there is a need to reorient and
motivate health personnel in educating diabetics about self- care18.
During the clinical experience the investigator has noticed that majority of patients
with diabetes mellitus do not take prescribed treatment, neglecting the do’s and don’ts of
diet and do not know the importance of exercise and foot care which leads to
complications. The investigator has observed that a number of diabetic patients are
hospitalized because of uncontrolled hyperglycemia, ulcers on foot, diabetic nephropathy,
neuropathy, hypertension and artherosclerosis19.
8
Patient noncompliance is a major medical problem in America. Consequently,
numerous studies and reports have been performed to articulate the meaning of the problem
and to suggest improvements. The literature however, in its effort to explore all facets of the
current compliance situation, has produced a complex construct, making it exceedingly
difficult for clinicians and researchers to understand the problem. This report was undertaken
to unify the current spectrum of compliance literature, to make sense of the adherence
situation. A variety or research methods was used, including MEDLINE and PubMed
searches, university medical library searches, general Internet searches, and clinical text
reviews. The result was a categorization of the literature into six segments, including articles
identifying adherence as a problem, identifying the causes of noncompliance and exploring
possible solutions, analyzing adherence with respect to specific ailments, and exploring the
patient's role, the pharmacist's role, and the physician's role with respect to compliance. After
the exploration and synthesis of the current literature, we suggest that future research
concentrate on the practitioner for a better understanding of the compliance situation and the
creation of a universal method of ensuring compliance39.
Diabetes imposes life long demands on client’s families. They have to make a multitude
of decisions related to managing diabetes and compliance, as diabetes affects all age group
worldwide. People with diabetes need to monitor their blood glucose, take medication,
exercise regularly and modify life styles. As outcomes are largely based on the decision they
take, it is of paramount importance that people with diabetes receive ongoing, high-quality
diabetes education that is tailored to their need and delivered by skilled health care providers.
During the clinical experience the investigator has noticed that majority of patients with
diabetes mellitus do not take prescribed treatment, neglecting the do’s and don’ts of diet and
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do not know the importance of exercise and foot care, etc which leads to complications. The
investigator felt the need to assess the level of compliance among patients. Which would help
community health nurses to plan implement culturally focused teaching program.
6.2. REVIEW OF LITERATURE:
“Man can learn nothing except by going from the known to unknown”
- Claude Bernard
Diabetes mellitus is silent disease and recognized as one of the fastest growing threats to
public health in almost all countries of the world. It is also called the “Disease of
prosperity”. It’s a chronic disorder with elevated blood sugar level and it requires careful
monitoring and control.
THE LITERATURE REVIEW HAS BEEN ARRANGED AND
PRESENTED IN THE FOLLOWING HEADING:
1. Studies related to Incidence and Prevalence of the Diabetes mellitus.
2. Studies related to self management and education.
3. Studies related to compliance of Diabetic Clients.
1. INCIDENCE AND PREVALENCE OF DIABETES MELLITUS:
World Health Organization (WHO) in 2007 reported that worldwide there are 246
million diabetic clients. 17.7 million in united states (US), 20.8 million in china, and 6.8
million in Japan. In the United Kingdom the prevalence of known diabetes is about 2% and
10
the age standardized prevalence of undiagnosed diabetes is 2% among the over frontier and
31.7 million cases in India. In the year 2008, India was estimated to have 40.2 million
diabetes. WHO forecasts that the number will rise to 14.5 million by the year 2025 21. But by
the year 2030, the estimated prevalence of diabetes mellitus was 30.3 million in US, 42.3
million in China, 13.9 million in Japan and 79.4 million in India. Diabetes Mellitus is the
fourth leading cause of death22. Arab Diabetes Survey 2006 reported that 10% of the
population was affected by diabetes mellitus. Out of which, 5.7% exists in urban areas, 4.1%
in rural areas and 1.5% among desert communities. Serious complications may affect a
considerable proportion of the population if the disease is not properly managed23.
According to the new data released by the International Diabetes Federation (IDF)
November 2009, 285 million people worldwide have diabetes which affects 7% of the
world’s adult population, 50.8 million of diabetes in India, 43.2 million in China, 26.8
million in US, 9.6 million in Brazil, 7.5 million in Germany, 7.1 million in Pakistan, 7.1
million in Japan, 7 million in Indonesia and 6.8 million in Mexico. It indicates that people in
low and middle income countries are bearing the brunt or burden of the epidemic, and that
the disease is affecting far more people of working age than previously believed24.
Diabetes is now emerging as one of the main threats to human health in the 21st
century. The past two decades have seen an explosive increase in the number of people
diagnosed world-wide. In recent years, India has witnessed a rapidly exploding epidemic of
diabetes. Indeed India today leads the world with its largest number of diabetics in any given
country. It has been estimated that in 1995, 19.4 million individuals were affected by
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diabetes in India and these numbers are expected to increase to 57.2 million by the year
2025 (one sixth of the world total) 25.
In the recent National Urban Diabetes Survey (NUDS) the prevalence of diabetes was
found to be 13.5% among Chennai residents, in Bangalore-12.4%, Hyderabad-16.6%,
Kolkata-11.7%, New Delhi-11.6% and Mumbai-9.3%. The survey also concluded that there
is a large pool of individuals with impaired glucose tolerance (IGT) at risk of conversion to
diabetes especially among the younger age group below 40 years25.
In the 14 year study conducted in 8793 hospitalised diabetics in Mumbai, 81.8%
developed complications. Hypertension was observed in 42.2%, ischemic heart diseases in
27.2%, cerebrovascular complications in 9.2% and peripheral vascular disease in 4.2%25.
A study conducted to estimate the prevalence of diabetes and the number of people
with diabetes who are less than 20 years of age in all countries of the world for three points
of time in 1995, 2000, and 2025. The data obtained by WHO was collected from 75
communities in 32 countries, was analysed for developing and developed countries
separately. Prevalence of diabetes in adults worldwide is estimated to be 4.0% (135 million)
in 1995 and is expected to rise to 5.4% (300 million) in 2025. Thus by the year 2025, more
than 75% of people with diabetes will reside in developing countries as compared to 62% in
1995. In developing countries the majority of people with diabetes are in the age group of
45-64 years and in the developed countries more than 64 years. Thus the study has
concluded that diabetes is a global burden26.
2. STUDIES RELATED TO SELF MANAGEMENT AND EDUCATION
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Management of clients with diabetes includes restoring and maintaining blood
glucose levels to near normal as possible by balancing the diet, exercise, and the use of oral
hypoglycemic agents or insulin. The treatment of diabetes is highly individualized, and it
depends on type of diabetes, complications, and presence of other active medical problems,
age and general health at the time of diagnosis. Diabetes can be managed with proper care,
clear understanding of the problem, proper treatment and regular follow up27.
The effects of a culturally competent diabetes self management education was studied
among Mexican Americans with Type 2 diabetes at Texas Mexican border. A total of 256
patients between 35 to 70 years of age with Type 2 diabetes were randomly assigned to
experimental and control group. The intervention involved 3 months of weekly instructional
sessions on nutrition, self – care topics, exercise and self-monitoring of blood glucose. Data
was analyzed by descriptive statistics. Experimental group showed significantly lower levels
of HbA1c and fasting blood glucose at 6 and 12 months and higher diabetes knowledge score
(r=0.88, p< 0.01) than the control group. This study confirms the effectiveness of culturally
competent diabetes self-management education on improving health outcomes particularly
for those individuals with HbA1c levels >10%28.
An evaluative study was conducted in Hawaii to assess the effectiveness of Diabetes
Out patient Intensive Treatment Program (DOIT) over educational mailing (Edupost).
Diabetic patients (Type 1 and 2) with poor glycemic control were randomly assigned to
DOIT and educational mailing .Group education and skills training experience combined
with daily medical management was carried out over a period of 6 months. The result
showed a significant drop in HbA1c values in both treatment groups and greater glycemic
13
control was evidenced in DOIT group. DOIT group also repo rted significant improvement
in self-care (blood glucose monitoring, exercise and diet) whereas Edupost patients showed
no improvement. For DOIT patients glycemic improvement was significantly associated
with self-reported change in diet (r=0.41, p<0.02) 29.
A study conducted to evaluate the efficacy of self-management education on
Glycosylated Hemoglobin (GHb) in adults with Type 2 diabetes. They analyzed 31
randomized control studies conducted during 1980 to 1999 to evaluate the efficiency of
Diabetes Self- Management Education (DSME). A total of 4263 patients participated.
DSME interventions were classified into one of the following categories by their primary
educational focus on knowledge, lifestyle behavior (including diet and physical activity)
skill development, including skills to improve glycaemic control and to prevent and identify
complications. The result showed significant decrease in GHb by 0.76% on average
intervention than the control group at immediate follow up, by 0.26% at 1-3 months of
follow up. GHb decreased more with additional contact time between participant and
educator. Study concluded that self- management education improves GHb levels at
immediate follow up and increased contact time increased the effect17.
A study conducted on “Diabetes self- Management reported recommendation and
patterns in a large population” concluded that comparisons on level of self management
across diabetes type revealed significant differences for diet and glucose testing. Diabetes
self- Management is the cornerstone of over all diabetes management20.
14
According to A comprehensive Guide to Diabetes (2001) the management of diabetes is
one of the most important subjects in clinical practice. Every 5th patient visiting a consulting
physician and every 7th patient visiting a family physician has diabetes.
3. STUDIES RELATED TO COMPLIANCE OF DIABETIC CLIENTS
A study was conducted in Bangalore to examine the efficacy of a comprehensive
behavioral intervention program in management of compliance to regimen in Type 1
diabetes and its effect on glycemic control. Clients suffering from Type 1 diabetes between
the ages of 15-22 years were randomly selected from local general hospital or diabetology
units. The experimental group had undergone 15 individual therapies over a period of three
months and the control group was seen three times for assessment. The findings of the study
revealed that both groups were non-compliance at pre treatment. The experimental group
improved significantly at post treatment (t=9.15, p<0.05). Similarly there has been
statistically at post treatment on Glycosylated hemoglobin with experimental group having
lower values (t=2.89, p<0.05)31.
A study was conducted to determine whether medication adherence is associated with
clinical outcomes in patients with diabetes. The study setting was a large integrated delivery
and financial system serving the residents of south eastern Michigan. The study population
consisted of 677 randomly selected patients aged ≥18 years with a diagnostic of diabetes,
hypercholesterolemia and hypertension. The main outcome measures were HbA1c LDL,
cholesterol level and blood pressure. Non-adherent patients had both statistically and
15
clinically worse outcome than adherent patients. A 10% increase of 0.14% in HbA1c and an
increase of 4mg/bl in LDL cholesterol level. The study highlighted the need for adherence to
medication32.
A study was conducted to evaluate the factors affecting medication adherence in
geriatric diabetic patients treated at private clinics and tertiary hospitals. We included 108
diabetic patients older than 65 years treated at one tertiary hospital and 157 patients older
than 65 years treated at two private clinics. The medication adherence based on Morisky's
self-report was significantly higher in tertiary hospital patients (61.1%) compared to private
clinic patients (43.2%) (P < 0.01). The results showed that drug storage and self-efficacy
were factors affecting adherence to medication in tertiary hospital patients (P < 0.05). The
adherence was high in cases of proper drug storage (odds ratio [OR], 5.401) and in cases
with high self-efficacy (OR, 13.114). In private clinic patients, financial level (P < 0.05),
recognition of the seriousness of diabetes complications (P < 0.05) and self-efficacy (P <
0.01) were associated with medication adherence The medication adherence was
significantly lower in patients whose financial state were moderate than those with lower
(OR, 0.410), and medication adherence was significantly higher in patients who had higher
perceived severity (OR, 2.936) and in patients with higher self-efficacy (OR, 4.040)33.
A study was to identify factors affecting the compliance of diabetes patients and to
examine the relationship between the compliance of the patients and the levels of HbA1c.
The subjects included 274 type 2 diabetes mellitus patients attending the diabetes mellitus
outpatient clinic of Somdet Prayannasangworn Hospital in Chiang Rai Province. The results
of this study were statistically significant differences in patient’s compliance behavior
16
regarding the relationship between the selected relationship between doctor and patients and
the patient’s perception of self-efficacy34.
This community-based study was undertaken in a rural primary health center area
near Chennai (Madras) in order to better understand treatment-seeking behavior, compliance
patterns, and reasons for noncompliance among rural diabetics. Compliance was indirectly
measured through patient interviews and drug use charts. Of the 112 patients interviewed,
72% had some symptoms at the time of diagnosis, and the majority of them were diagnosed
in government health centers. Noncompliance was seen in 57% of the 112 patients
interviewed, and reasons were elicited. Interruption of treatment was significantly associated
with lack of education. The study identified the lack of a patient-friendly, flexible health
care system as the primary reason for noncompliance35.
STATEMENT OF THE PROBLEM:-
A descriptive study on assessment of compliance among diabetic clients regarding
diabetic management in Kadugudi PHC at Bangalore.
6.3 OBJECTIVES :-
1. To assess the level of compliance among Diabetic clients regarding diabetic
management.
2. To determine the relationship between the level of compliance and selected socio
demographic variables.
17
HYPOTHESIS :-
H1: There is a significant relationship between level of compliance and selected
socio demographic variables among diabetic clients.
OPERATIONAL DEFINITIONS :-
ASSESSMENT: Measuring the compliance of diabetic clients regarding diabetic
management using structured interview technique.
COMPLIANCE: Adherence to a recommended course of management by diabetic client
in relation to diet, medication, exercises, follow up, etc...
DIABETIC CLIENT: Clients who are diagnosed to be diabetes mellitus and taking
treatment for minimum 1 year.
DIABETIC MANAGEMENT: It is a measures taken by diabetic clients to control the
diabetes mellitus and prevent its complications.
ASSUMPTION:-
A1: The level of compliance differs among diabetic clients.
A2: Socio demographic variables influences the level of compliance
A3: Mass Medias impacts the compliance level of diabetic clients.
7. MATERIALS METHODS : -
7.1. SOURCE OF DATA: - Diabetic Clients attending Kadugudi PHC at Bangalore.
7.2 METHOD OF DATA COLLECTION PROCEDURE:-
18
RESEACH APPROACH: Non Experimental research approach.
RESEARCH DESIGN: Descriptive Research design.
SAMPLING TECHINIQUE: Convenience sampling technique.
SAMPLE SIZE: 100
SETTING OF THE STUDY: The descriptive study will be conducted among diabetic
clients in Kadugudi PHC at Bangalore. The Kadugudi PHC covers the area of 25 kilometers
and it is 23 kilometers from Dr.Syamala Reddy College of Nursing. It covers the population
of 42,809 with the bed strength of 12. The services provided by the Kadugudi PHC are
emergency treatment, medical care, control of communicable disease, health education,
family planning, immunization, MCH services, etc…. Kadugudi PHC has 2 medical officers
with other 12 staffs.
SAMPLING CRITERIA :-
INCLUSION CRITERIA:
Diabetic clients those who are willing to participate in the study.
Diabetic clients those who can able to understand Kannada & English.
Diabetic clients with age up to 65 years.
Clients with history of diabetes for minimum 1 year.
EXCLUSION CRITERIA:
Diabetic clients with other chronic illness such as Hypertension, Asthma, Arthritis,
Cancer etc.
DATA COLLECTION TOOL: -
19
Section I-Socio demographic variable such as age, sex, education, occupation, income,
religion, marital status, type of family, dietary pattern, age at the onset of diabetes, nature
of treatment, etc…
Section II – Structured Interview schedule on compliance of diabetic clients in relation to
diet, medication, exercise, follow up, etc..
7.3. DATA COLLECTION PROCEDURE :-
This descriptive study will be conducted in Kadugudi PHC at Bangalore, with a
sample of 100 Diabetic clients. A structured interview schedule will be used to
collect the relevant information regarding level of compliance. The duration of data
collection will be for 4 weeks.
DATA ANALYSIS METHOD :-
The collected data will be analyzed using descriptive statistics such as frequency
distribution, percentage, mean and standard deviation for socio demographic variables and
compliance, and inferential statistics such as chi square to see the association between the
socio demographic variables and compliance.
7.4 ETHICAL CLEARNCE
Yes
Ethical clearance will be obtained from PHC and oral consent from participants.
Confidentiality of the subjects will be maintained.
20
8. LIST OF REFERENCE:-
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India Private Ltd, 2002.
6) Times of India, 14th November 2010.
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diabetes and prediabetes.
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9 Signature of Candidate
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10 Remarks of the Guide
11 Name and Designation
11.1 Guide
11.2 Signature
11.3 Co-guide
11.4 Signature
11.5 Head of the Department
11.6 Signature
12 12.1 Remarks of the Chairman and Principal
12.2 Signature
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