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Dr. Heleen Riper [email protected] Innovation Centre of Mental Health & Technology Sustainable prevention with e- mental health INPES April 2010

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Page 1: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Dr. Heleen [email protected]

Innovation Centre of Mental Health & Technology

Sustainable prevention with e-mental health

INPES April 2010

Page 2: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

What would do?

Page 3: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

What would do?

Page 4: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

1 out of 4 mental health problem in lifetime

Page 5: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

1 per 15 YP

Page 6: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

1 million suicides per year

Page 7: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

0

2

4

6

8

10

12

Disease burden in 2030

Worldwide

% o

f tot

al D

ALY

Source: Mathers & Loncar, 2006

0

2

4

6

8

10

12

High-income countries

Cataracts

HIV/AID

S

Depression

Is. h

eart dise

ase

Road traffi

c

Perinata

l

Cerebrovascu

lair

COPD

chest

infections

Hearing l

oss

Alzheim

er / dementias

Depression

Is. h

eart dise

ase

Alcohol

Diabetes

Cerebrovascu

lair

Hearing l

oss

Lung c

ance

rs / in

fections

Osteart

hritis

COPD

% o

f tot

al D

ALY

Page 8: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

more people less money transition chonic diseases

self-managementlife style

Page 9: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

health decisions are made by ..

Page 10: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

EMH 2000 - 2010co

sts

treatment duration and intensity

effect sizessmall medium

large

mental fitness

prevention

treatment

relapse preventioncare

population health gainlarge medium

small

© Riper 2008

Page 11: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Is it scalable from research into the

Real World?

Page 12: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

33%

73%

5%

60%

Developing

Developed

World

% m

obile

sub

s.

90% 25% 17%

5%

1998

1999

2000

2001

2002

2003

2004

2005

2006

2007

020406080

100120

Internet Penetration

Page 13: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Study N Target group Comp CYL/WL/ 12 wks* significant

Spek 2008 301 50+ d= 0.55

Warmerdam 2008 268 18+ d= 0.69

De Graaf 2009 303 18+ d= 0.20

Voordouw 2009 6568/1111

18 + d= 1.09 (Pre-post within)

Color Your Life

Page 14: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Drinking Less

Page 15: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

*P<0.001

Drinking Less Real World N= 378 ITT

N/ RCT

Target Group Successful drinking at 6 months

Successful drinking at 12 months

261 14/21 SU Alcohol weekly and/or 6/4 per occasion

17,2% DL5,4 % Control(p= .008)

13,6% DL5,5% Control(p<.05)

6 months 12 months

Percentage successful

18,8 %* 17,5 %*2.750 monthly visitors1 out of 16 starts with DLMean 40.9 (25.2 SD) SU WeeklyAUDIT: M 20.27 (sd 6.30)6 months study period: N= 972Response rate 39%Drop out 59% & 56%

Page 16: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Theory: 4 possible outcomes

Modelling cost-effectiveness of eHealth interventions 16

More costsLess effect

Fewer costsLess effect

More costsMore effect

Fewer costsMore effect

Page 17: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Example 1: Self-help in depression

Modelling cost-effectiveness of eHealth interventions 17

-7.500

-5.000

-2.500

0

2.500

5.000

7.500

10.000

-0,40 -0,20 - 0,20 0,40 0,60 0,80

Additional effects

Ad

dit

ion

al c

ost

s

Smit F, Willemse G, Koopmanschap M, Onrust S, Cuijpers P, Beekman A. (2006) Cost-effectiveness of preventing depression in primary care patients: randomised trial. British Journal of Psychiatry 188: 330-336

Page 18: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Example 2: eHealth v waitlist

Modelling cost-effectiveness of eHealth interventions 18

-500

-0.20 - 0.20 0.40

Additional effects

Additio

nal

cost

s

Page 19: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Example 3: eHealth v Group CBT

Modelling cost-effectiveness of eHealth interventions 19

-2,000

500

-0.20 - 0.20 0.40

Additional effects

Additio

nal costs

Page 20: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Key messages

Modelling cost-effectiveness of eHealth interventions 20

Page 21: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010
Page 22: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

low sesetnic cultural minoritiesrecruitment

acceptable interventions

visual screener

Page 23: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Visual Screener

Page 24: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

Visual Screener Depression, Anxiety &Alcohol DutchN=86

TurkishN= 82

1. How do you feel? depression 0.39 r 0.21 r2. How did you feel in the past two weeks? depression 0.47 r 0.29 r3. Do you worry a lot? GAD 0.46 r 0.30 r4. Do you sometimes suddenly panic? Panic 15.14 χ2 21.94 χ2

5. Are you afraid of busy places that are difficult to leave?

AGO 0.53 χ2 n.s. 7.28 χ2

6. Is there something that you are very afraid of? Specific Phobia 21.30 χ2 6.53 χ2

7. Are you afraid of being watched by people? Social Fobia 14.22 χ2 1.33 χ2 n.s.

8. Have you ever experienced something horrible?

PTSD 24.39 χ2 12.32 χ2

9. Do you sometimes have unpleasant thoughts that won’t go away?

OCD 5.58 χ2 0.92 χ2 n.s.

10. Do you ever think about your own death? Alcohol 0.70 r 0.22 r11. Do you ever think of killing yourself? Suicide 23.47 χ2 4.29 χ2

Validadion Visual Screener

Page 25: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

effective scalable acceptable

planned effortsknowledge

turning point sustainablefilling the gap

health gain

Page 26: Dr. Heleen Riper hriper@trimbos.nl Innovation Centre of Mental Health & Technology Sustainable prevention with e-mental health INPES April 2010

thank you for your attention

Heleen [email protected]