U251 MCF-7 A549

- + - - + - - + - scrambled ODN- - + - - + - - + As-miR-221/222

U6

miRNA-221

miRNA-222

Zhang et al Supplemental figure S1

Figure S1. MiR-221/222 knock-down by antisense oligonucleotides. U251, MCF-7 and A549 cells were transfected with either scrambled ODN or as-miRNA-221/222 followed by Northern blot analysis using indicated probes.