Transcript
Page 1: THE ACTION OF TOXINS ON THE CENTRAL NERVOUS SYSTEM

565RED CROSS AND KINDRED WORK IN SWITZERLAND.

departments of the respective territories are

willing to provide land, and sufficient is saidto indicate to those who read between thelines as to the class of man or family whowould be likely to benefit by the emigrationsuggested. The knowledge acquired from Sir RiderHaggard’s report will, however, have to be supple-mented by closer inquiry before any prudentdecision can be arrived at by individuals. An

interesting discussion conducted by correspondencebetween Sir Rider Haggard, Mr. Jesse Collings,and Mr. Wilmot Corfield upon the comparativeclaims of settlement upon the land in GreatBritain and oversea will be found included. Weare inclined to think that Sir Rider Haggard hasthe best of the argument so far as it carries us, andthat his reasons in favour of emigration, as well asthe facts that underlie them, are likely to weighwith many of those who some day may consulthis report when making their plans. It is easy toprophesy, as Mr. Collings does, that for these men" there will be no sufficient employment in theindustrial world in England," but we would ratherwait till war has ceased for six months or evenfor a year or two before settling in our mindswhat the demands of industry will be. It iseasy, again, to write of " nine-tenths of Englandthat might be cultivated." We have seen similarstatements elsewhere of a huge acreage whichmight be cultivated in Cornwall, a county whichin many districts is extremely fertile. It is, how-ever, a different task to enable men to whom agri-culture may be a new pursuit to earn a living wheretheir ancestors, when farming prosperously, failed to"

see money " in further reclamation of land. Thedefinite prospect of making a livelihood will be thecondition which the prudent will ask for. Ahealthier life in freer surroundings for themselvesand their families will be the attraction that willweigh in the balance when the relative merits ofurban and rural industries come to be estimated.

THE ACTION OF TOXINS ON THE CENTRALNERVOUS SYSTEM.

AN account of some interesting and importantobservations on the conveyance of toxins to thecentral nervous system and of their action there isgiven in a paper which is published in the Augustnumber of the Eàinbupgh Medical JournaZ by Dr.David Orr and Major R. G. Rows, R.A.M.C. As theresult of a study of many cases of suppurative andother septic conditions, they found that there takesplace a spread of the toxin by means of the lym-phatics of the nerve trunks, and that the poisonenters the spinal cord at the site of " origin " of thenerve and attacks the nerve-fibres at the pointwhere they lose their covering of neurilemma.The degeneration can sometimes be traced from theanterior roots into the grey matter, where it termi-nates among the cells. To confirm these observa-tions experiments were made on animals by placingcelloidin capsules containing pathogenic organismsin contact with selected nerves, and examining thenerves and central nervous system subsequently.The results corresponded with those seen in humandisease. Thus when the sciatic nerve was involved,a degeneration of the exogenous system of fibres inthe posterior columns of the cord was induced,beginning, as in the human cases, where the fibreslose their sheaths, and involving the root-entry zoneand the collaterals passing into the posteriorcornua. If nerves in the cheek were selected, the

degeneration passed into the pons and medulla.Hence it seems proved that poisons pass alongthe lymph-channels of the nerves and exerta direct local action on the cord and medulla,passing round the cord to some extent andentering along with the prolongation of the pia-arachnoid. Other experiments were made tosimulate a hsematogenous intoxication by placingthe infective capsules in the peritoneal cavity, inwhich case no direct neuritis of peripheral nervesresulted, the condition resembling an alimentarytoxaemia. In these cases there were found a

primary degeneration of the myelin sheaths offibres round the periphery of the cord, oedema ofthe cord, proliferation of the peri-vascular neuroglia,and dilatation of the vessels with hyaline throm-bosis. In this last the hyaline material first layalong the sides of the vessels, giving rise to a net-work extending from side to side, and finallyobliterating the lumen completely. Although inthese cases there is apparently a hasmatogenousinfection, the observers suggest that the poison alsoaffects the sympathetic nerves, thus exciting thevascular reaction observed. Applying the resultsto human neurology, it would appear that acuteand chronic myelitis are due to infection ascendingalong the nerve trunks. Dementia paralytica isalso to be regarded as a chronic inflammatorydisease of lymphogenous origin, and tabes dorsalisis similarly produced. Infantile paralysis falls intothe same group, the most striking member of whichis seen in Landry’s paralysis. On the other hand,the affections of the cord which are met with inanaemia, Addison’s disease, and so forth, are to beclassed as heematogenous, showing no inflammatorylesions.

RED CROSS AND KINDRED WORK INSWITZERLAND.

THE recent statement in the press that 50 Frenchnurses are being entertained at Montreux for threeweeks as guests of the Swiss Government suggestsa review of the various forms of beneficent actionin which Switzerland has engaged during the pasttwo years. It will be known to all that Geneva wasthe home of the Red Cross movement and thebirthplace of Henri Dunant, who devoted his lifeto it. Far from obtaining due personal recogni-tion for his work or material reward, he was formuch of the latter part of his life unknown andin want, and only when he was quite a broken-down old man, just maintaining his existence ata nursing home above the Lake of Constance, didany public recognition of his life work come tohim in the form of an annuity from the EmpressMother of Russia and of one of the Nobel prizes.The Bernese Comite de Secours aux Prisonniers deGuerre arose in December, 1914, as a branch of theSwiss Red Cross. For almost two years it has senta constant stream of food and clothing to necessi-tous prisoners in all countries, with special atten-tion to the invaded regions with their dispossessedinhabitants. Up to the beginning of August150,000 packets have been sent, and the Italianinternes in Austria have been the concern of themost recent branch of the work at Lugano. Fromthe beginning of the war Geneva has been thebureau of exchange for information concerningprisoners of war and 2000 or more voluntaryworkers have been constantly engaged in puttingrelatives in touch with "missing" soldiers. Thismeans of inter-communication was available long

Top Related