MicroRNA expression in polarized macrophages
Table S3. Changes in miRNA expression in polarized MDMs relative to untreated controls. miRNA identity and assay # No
Treatment M1 M2a M2b M2c Mean Fold Change
D1 D2 D3 D1 D2 D3 D1 D2 D3 D1 D2 D3 D1 D2 D3 M1 M2a M2b M2c
hsa-let-7a*-4395418 1 1 1 0.81 0.791 0.603 0.584 1.155 1.045 0.884 1.117 1.152 1.687 0.825 0.408 0.735 0.928 1.051 0.973
hsa-let-7a-4373169 1 1 1 0.937 1.095 1.139 0.948 1.001 1.18 0.874 0.927 0.974 0.973 0.838 1.289 1.057 1.043 0.925 1.033
hsa-let-7b-4395446 1 1 1 1.656 0.704 0.442 0.729 0.735 0.846 1.219 0.69 0.669 1.299 0.698 0.875 0.934 0.770 0.859 0.957
hsa-let-7c-4373167 1 1 1 0.706 0.932 0.834 0.681 1.169 0.805 0.699 0.821 0.778 0.684 1.007 0.752 0.824 0.885 0.766 0.814
hsa-let-7d-4395394 1 1 1 0.845 0.818 1.167 0.861 0.889 1.079 1.001 0.883 0.878 0.953 0.863 1.538 0.943 0.943 0.921 1.118
hsa-let-7e*-4395518 1 1 1 3.176 0.673 3.042 0.776 0.711 2.621 1.284 0.388 2.84 1.93 0.566 0.719 2.297 1.369 1.504 1.072
hsa-let-7e-4395517 1 1 1 0.928 0.763 1.138 1.04 0.675 0.933 0.861 0.785 0.859 1.035 0.743 1.16 0.943 0.883 0.835 0.979
hsa-let-7f-4373164 1 1 1 0.672 0.625 0.968 0.885 0.625 0.743 0.922 0.651 0.598 0.708 0.605 0.885 0.755 0.751 0.724 0.733
hsa-let-7g*-4395229 1 1 1 0.87 0.715 0.847 0.909 0.6 1.032 0.939 0.567 0.907 0.998 0.286 0.7 0.811 0.847 0.804 0.661
hsa-let-7g-4395393 1 1 1 1.307 1.029 1.228 1.177 1.039 0.843 1.009 1.105 0.906 1.032 0.999 0.982 1.188 1.020 1.007 1.004
hsa-let-7i*-4395283 1 1 1 1.168 1.692 0.817 0.788 1.596 1.03 1.052 1.063 0.512 0.944 0.851 0.695 1.226 1.138 0.876 0.830
hsa-miR-100-4373160 1 1 1 0.565 1.147 1.099 0.449 0.948 6.866 0.571 1.009 1.442 0.453 0.836 1.088 0.937 2.754 1.007 0.792
hsa-miR-101-4395364 1 1 1 1.03 1.157 0.814 1.039 1.104 1.039 1.17 1.095 0.971 0.982 1.078 1.111 1.000 1.061 1.079 1.057
hsa-miR-103-4373158 1 1 1 0.988 0.92 0.947 1.031 0.876 0.93 0.987 0.96 0.852 0.946 0.833 1.013 0.952 0.946 0.933 0.931
hsa-miR-106a-4395280 1 1 1 1.098 1.037 0.732 1.106 1.015 0.812 1.012 0.986 0.811 1.018 0.909 0.865 0.956 0.978 0.936 0.931
hsa-miR-106b*-4395491 1 1 1 0.928 0.999 1.107 1.094 0.734 0.934 0.879 1.03 0.971 0.741 0.928 1.04 1.011 0.921 0.960 0.903
hsa-miR-106b-4373155 1 1 1 1.335 1.215 0.965 1.262 1.048 0.897 1.15 0.999 0.881 1.083 0.912 0.996 1.172 1.069 1.010 0.997
hsa-miR-10a-4373153 1 1 1 0.936 0.874 1.141 0.9 0.865 0.969 0.87 0.843 1.003 0.9 0.825 1.039 0.984 0.911 0.905 0.921
hsa-miR-122-4395356 1 1 1 0.642 0.99 1.278 0.717 0.693 1.044 0.819 1.088 1.273 0.64 1.14 1.44 0.970 0.818 1.060 1.073
hsa-miR-125a-3p-4395310 1 1 1 2.254 3.529 2.002 0.601 1.104 1.013 1.086 2.223 0.926 1.044 0.955 1.25 2.595 0.906 1.412 1.083
hsa-miR-125a-5p-4395309 1 1 1 1.053 1.297 0.789 0.717 0.996 0.954 0.883 1.11 0.727 0.718 0.913 0.81 1.046 0.889 0.907 0.814
hsa-miR-125b-4373148 1 1 1 1.126 1.485 1.016 1.268 0.908 1.136 1.153 1.102 1.092 0.792 0.891 1.046 1.209 1.104 1.116 0.910
hsa-miR-126*-4373269 1 1 1 1.206 1.254 0.707 0.912 1.065 0.895 1.038 1.258 0.933 0.91 0.928 0.881 1.056 0.957 1.076 0.906
hsa-miR-126-4395339 1 1 1 1.064 1.09 0.817 0.981 1.026 0.895 1.188 1.129 0.944 1.172 0.988 0.904 0.990 0.967 1.087 1.021
hsa-miR-127-3p-4373147 1 1 1 0.558 0.712 0.904 0.498 0.886 0.998 0.794 1.106 0.694 0.536 0.962 0.874 0.725 0.794 0.865 0.791
hsa-miR-128-4395327 1 1 1 0.825 1.073 0.835 0.961 1.041 0.763 0.854 1.025 0.731 0.832 1.006 0.819 0.911 0.922 0.870 0.886
hsa-miR-130a-4373145 1 1 1 0.921 1.174 1.124 0.993 0.891 1.087 0.774 0.828 0.847 0.755 0.74 1.23 1.073 0.990 0.816 0.908
hsa-miR-130b*-4395225 1 1 1 1.017 1.203 0.48 0.857 1.296 0.764 0.869 1.456 0.619 0.844 0.885 0.658 0.900 0.972 0.981 0.796
hsa-miR-130b-4373144 1 1 1 0.696 1 0.909 0.778 1.066 1.181 0.95 1.173 0.961 0.738 0.972 1.184 0.868 1.008 1.028 0.965
MicroRNA expression in polarized macrophages
hsa-miR-132*-4395243 1 1 1 1.87 1.913 1.225 0.726 1.009 0.522 3.911 4.698 1.261 0.877 1.229 0.958 1.669 0.752 3.290 1.021
hsa-miR-132-4373143 1 1 1 1.301 1.798 0.852 0.939 0.986 0.738 1.902 1.889 0.921 0.838 0.834 0.844 1.317 0.888 1.571 0.839
hsa-miR-133a-4395357 1 1 1 0.818 1.049 0.59 0.818 0.964 0.68 0.895 0.89 0.706 0.81 0.755 9.268 0.819 0.821 0.830 3.611
hsa-miR-135a*-4395343 1 1 1 1.173 1.124 0.753 0.937 1.15 0.892 0.971 1.196 0.759 0.981 0.996 0.779 1.017 0.993 0.975 0.919
hsa-miR-135a-4373140 1 1 1 0.463 1.085 0.564 0.653 0.555 1.341 0.787 0.57 0.667 0.531 0.711 1.049 0.704 0.850 0.675 0.764
hsa-miR-135b-4395372 1 1 1 1.019 0.927 0.981 1.031 1.026 0.797 0.952 0.909 0.729 1.254 0.867 0.81 0.976 0.951 0.863 0.977
hsa-miR-136*-4395211 1 1 1 1.198 1.025 0.639 2.639 0.49 1.421 0.826 0.828 1.028 0.566 1.025 1.363 0.954 1.517 0.894 0.985
hsa-miR-137-4373301 1 1 1 1.872 0.865 1.051 2.238 0.461 1.729 2.002 0.652 1.26 1.585 0.922 1.794 1.263 1.476 1.305 1.434
hsa-miR-138-1*-4395273 1 1 1 0.856 1.202 1.616 1.054 1.164 1.29 0.803 1.124 1.636 1.005 1.656 1.644 1.225 1.169 1.188 1.435
hsa-miR-138-4395395 1 1 1 0.986 1.633 0.827 1.358 1.145 0.761 0.96 1.206 0.88 1.004 1.217 0.811 1.149 1.088 1.015 1.011
hsa-miR-139-5p-4395400 1 1 1 0.893 0.808 0.542 0.719 0.744 0.678 1.191 1.17 0.801 0.751 0.874 1.153 0.748 0.714 1.054 0.926
hsa-miR-140-3p-4395345 1 1 1 1.009 0.968 0.713 0.98 1.012 0.756 1.073 1.045 0.926 1.062 0.963 0.919 0.897 0.916 1.015 0.981
hsa-miR-140-5p-4373374 1 1 1 0.836 1.019 0.773 0.826 1.003 0.804 0.852 1.057 0.762 0.885 1.006 0.928 0.876 0.878 0.890 0.940
hsa-miR-141-4373137 1 1 1 1.385 1.165 1.053 1.181 0.884 1.189 1.547 0.954 1.045 1.424 0.902 1.665 1.201 1.085 1.182 1.330
hsa-miR-142-3p-4373136 1 1 1 1.214 1.256 0.933 1 1.055 1.216 1.181 1.045 0.981 0.949 0.971 1.402 1.134 1.090 1.069 1.107
hsa-miR-142-5p-4395359 1 1 1 1.197 1.391 1.121 1.271 1.274 1.34 1.308 1.151 1.083 1.098 1.206 1.563 1.236 1.295 1.181 1.289
hsa-miR-1-4395333 1 1 1 1.293 1.304 0.786 1.426 1.019 0.579 0.937 3.645 0.41 0.997 1.777 0.751 1.128 1.008 1.664 1.175
hsa-miR-144*-4395259 1 1 1 0.889 1.095 2.811 0.834 0.585 2.645 0.357 0.767 2.025 0.877 0.472 2.617 1.598 1.355 1.050 1.322
hsa-miR-145-4395389 1 1 1 0.796 0.893 0.639 0.953 0.916 0.715 0.982 0.917 0.864 0.873 0.775 0.776 0.776 0.861 0.921 0.808
hsa-miR-146a-4373132 1 1 1 1.152 1.223 1.222 1.077 0.99 0.827 1.254 1.06 0.946 0.974 0.839 0.917 1.199 0.965 1.087 0.910
hsa-miR-146b-3p-4395472 1 1 1 1.559 1.424 1.196 1.065 1.188 0.778 1.427 1.486 0.786 0.996 1.165 0.873 1.393 1.010 1.233 1.011
hsa-miR-146b-5p-4373178 1 1 1 0.894 1.258 0.954 0.871 1.079 0.89 0.967 1.157 0.843 0.833 0.991 0.914 1.035 0.947 0.989 0.913
hsa-miR-147b-4395373 1 1 1 1.507 1.478 1.601 0.908 0.692 0.865 1.618 1.409 1.327 1.111 1.02 1.042 1.529 0.822 1.451 1.058
hsa-miR-148a-4373130 1 1 1 0.671 1.307 1.24 0.921 1.143 1.026 0.872 1.404 1.013 0.82 1.044 1.021 1.073 1.030 1.096 0.962
hsa-miR-148b*-4395271 1 1 1 1.047 0.872 0.902 0.849 1.097 0.85 0.884 0.943 0.917 0.942 0.905 1.012 0.940 0.932 0.915 0.953
hsa-miR-148b-4373129 1 1 1 1.059 1.098 1.255 1.019 1.215 1.03 1.134 1.376 1.042 0.993 1.024 0.941 1.137 1.088 1.184 0.986
hsa-miR-150-4373127 1 1 1 0.958 1.24 0.88 0.966 1.153 0.955 0.929 1.108 0.904 0.93 1.006 0.965 1.026 1.025 0.980 0.967
hsa-miR-151-3p-4395365 1 1 1 1.229 0.899 0.723 1.015 1.21 0.946 1.168 0.969 0.693 1.021 0.831 0.84 0.950 1.057 0.943 0.897
hsa-miR-152-4395170 1 1 1 0.843 0.957 1.018 0.905 1.011 1.006 0.931 1.028 0.945 0.859 0.85 1.047 0.939 0.974 0.968 0.919
hsa-miR-155*-4395398 1 1 1 4.817 4.126 8.945 1.098 2.162 0.95 5.804 6.338 4.174 0.519 0.712 0.837 5.963 1.403 5.439 0.689
hsa-miR-155-4395459 1 1 1 1.15 1.254 1.29 0.633 0.953 0.717 0.819 1.476 1.24 0.484 0.95 0.978 1.231 0.768 1.178 0.804
hsa-miR-15a*-4395530 1 1 1 1.087 1.388 0.696 1.306 1.763 1.066 0.948 1.369 0.755 1.045 1.596 0.974 1.057 1.378 1.024 1.205
hsa-miR-15b-4373122 1 1 1 0.96 1.217 1.094 0.995 0.981 1.063 0.998 1.048 0.917 0.941 0.916 1.085 1.090 1.013 0.988 0.981
hsa-miR-16-1*-4395531 1 1 1 1.426 0.823 0.825 1.478 1.253 1.246 0.896 0.833 0.68 1.431 1.283 1.352 1.025 1.326 0.803 1.355
MicroRNA expression in polarized macrophages
hsa-miR-16-4373121 1 1 1 0.577 0.979 0.966 0.751 0.874 0.786 0.661 0.991 0.775 0.638 0.991 0.764 0.841 0.804 0.809 0.798
hsa-miR-17-4395419 1 1 1 0.899 1.203 0.91 0.787 1.128 0.848 0.738 1.158 0.869 0.762 0.992 0.971 1.004 0.921 0.922 0.908
hsa-miR-181a*-4373086 1 1 1 0.524 0.399 0.597 0.577 0.594 0.962 0.485 0.379 0.84 0.803 0.6 1.109 0.507 0.711 0.568 0.837
hsa-miR-181a-2*-4395428 1 1 1 0.832 0.887 1.276 1.031 1.334 1.22 0.726 0.929 1.076 1.259 1.209 1.022 0.998 1.195 0.910 1.163
hsa-miR-184-4373113 1 1 1 0.847 0.797 1.519 0.987 0.553 0.604 1.011 0.872 1.29 0.776 0.403 1.211 1.054 0.715 1.058 0.797
hsa-miR-185-4395382 1 1 1 0.997 0.947 0.973 1.264 1.027 1.117 1.131 0.899 1.074 1.166 0.944 1.266 0.972 1.136 1.035 1.125
hsa-miR-186-4395396 1 1 1 0.847 1.133 0.792 1.062 1.01 0.92 0.854 1.168 0.782 1.133 1.044 0.889 0.924 0.997 0.935 1.022
hsa-miR-188-5p-4395431 1 1 1 1.118 1.299 0.748 1.172 1.314 1.134 1.154 1.252 0.73 1.182 1.293 0.876 1.055 1.207 1.045 1.117
hsa-miR-18a*-4395534 1 1 1 1.07 1.071 0.961 1.201 1.362 1.202 0.774 0.883 0.649 1.224 0.973 0.892 1.034 1.255 0.769 1.030
hsa-miR-18a-4395533 1 1 1 0.968 1.096 1.012 1.015 1.068 0.789 0.921 1.131 0.803 0.84 0.911 0.924 1.025 0.957 0.952 0.892
hsa-miR-190-4373110 1 1 1 0.747 1.055 0.91 0.821 0.98 1.115 1.297 0.845 0.758 0.803 0.985 1.232 0.904 0.972 0.967 1.007
hsa-miR-190b-4395374 1 1 1 1.31 1.038 0.661 1.089 1.1 0.816 1.194 1.048 0.95 1.084 1.068 0.799 1.003 1.002 1.064 0.984
hsa-miR-191-4395410 1 1 1 0.971 1.054 0.845 1.104 1.112 0.889 1.035 1.073 0.786 1.11 1.039 1.067 0.957 1.035 0.965 1.072
hsa-miR-192*-4395383 1 1 1 1.55 0.654 1.415 0.929 0.958 0.97 1.743 1.342 1.995 1.899 0.569 0.947 1.206 0.952 1.693 1.138
hsa-miR-192-4373108 1 1 1 0.961 1.079 0.999 0.998 0.981 0.926 1.209 1.288 1.232 0.95 0.889 0.94 1.013 0.968 1.243 0.926
hsa-miR-193a-3p-4395361 1 1 1 1.571 1.457 1.178 1.342 1.281 1.261 1.767 1.491 1.225 1.02 1.398 1.428 1.402 1.295 1.494 1.282
hsa-miR-193a-5p-4395392 1 1 1 0.909 1.055 0.988 0.883 0.988 0.868 1.072 1.167 0.855 1.012 1.064 1.079 0.984 0.913 1.031 1.052
hsa-miR-193b-4395478 1 1 1 0.744 0.95 0.897 1.72 3.665 1.558 0.751 0.785 0.799 0.768 0.867 0.782 0.864 2.314 0.778 0.806
hsa-miR-194-4373106 1 1 1 1.107 1.219 1.098 1.122 0.855 0.839 1.339 1.237 0.942 1.115 0.827 0.892 1.141 0.939 1.173 0.945
hsa-miR-195-4373105 1 1 1 1.264 1.006 0.939 1.184 1.152 1.037 1.15 1.044 0.989 1.332 0.923 1.032 1.070 1.124 1.061 1.096
hsa-miR-196b-4395326 1 1 1 0.734 0.671 1.011 0.835 0.764 0.868 1.153 0.886 1.194 0.891 0.612 0.929 0.805 0.822 1.078 0.811
hsa-miR-199a-3p-4395415 1 1 1 0.962 0.957 0.861 1.086 0.879 0.778 1.034 1.003 0.933 0.906 0.864 0.896 0.927 0.914 0.990 0.889
hsa-miR-19a-4373099 1 1 1 0.892 0.931 0.912 0.787 0.982 0.896 0.787 0.8 0.831 0.777 0.914 0.975 0.912 0.888 0.806 0.889
hsa-miR-19b-1*-4395536 1 1 1 1.262 0.977 0.843 1.264 1.385 1.064 1.037 0.922 0.843 1.085 1.021 1.194 1.027 1.238 0.934 1.100
hsa-miR-19b-4373098 1 1 1 1.014 1.069 0.937 1.022 0.96 0.856 1.037 0.953 0.844 0.963 0.889 0.958 1.007 0.946 0.945 0.937
hsa-miR-200b-4395362 1 1 1 0.647 1.054 0.815 0.667 0.85 0.732 0.637 1.073 0.872 0.64 0.83 1.077 0.839 0.750 0.861 0.849
hsa-miR-200c-4395411 1 1 1 1.021 1.103 1.031 0.952 0.876 0.784 0.906 1.002 0.751 0.958 0.851 1.17 1.052 0.871 0.886 0.993
hsa-miR-203-4373095 1 1 1 1.399 1.499 0.731 1.526 1.481 0.982 1.412 1.448 0.764 1.49 0.859 0.901 1.210 1.330 1.208 1.083
hsa-miR-206-4373092 1 1 1 1.146 0.466 1.132 0.969 0.739 0.484 0.771 0.644 0.557 1.476 0.373 0.841 0.915 0.731 0.657 0.897
hsa-miR-20a*-4395548 1 1 1 1.426 1.215 0.918 1.178 1.353 1.055 1.193 0.983 0.985 1.048 0.933 0.931 1.186 1.195 1.054 0.971
hsa-miR-20a-4373286 1 1 1 1.042 0.913 0.901 0.834 0.867 0.958 1.093 0.885 0.922 0.833 0.819 1.015 0.952 0.886 0.967 0.889
hsa-miR-20b-4373263 1 1 1 0.86 0.98 1.01 0.902 0.881 0.938 0.873 0.918 0.972 0.922 0.887 1.044 0.950 0.907 0.921 0.951
hsa-miR-21*-4395549 1 1 1 1.762 1.508 0.918 1.749 2.191 1.616 1.549 1.333 0.866 1.108 1.024 0.94 1.396 1.852 1.249 1.024
hsa-miR-210-4373089 1 1 1 0.864 1.351 1.102 0.897 0.99 0.886 0.843 1.711 1.039 0.674 0.982 0.984 1.106 0.924 1.198 0.880
MicroRNA expression in polarized macrophages
hsa-miR-212-4373087 1 1 1 1.743 2.09 0.793 1.105 1.082 0.841 2.665 2.428 0.987 1.222 0.885 1.006 1.542 1.009 2.027 1.038
hsa-miR-21-4373090 1 1 1 0.756 1.108 1.183 0.774 0.962 0.885 0.748 0.997 0.831 0.614 0.862 0.959 1.016 0.874 0.859 0.812
hsa-miR-218-4373081 1 1 1 0.939 1.318 0.92 0.908 1.106 0.996 1.032 1.079 0.966 0.821 0.933 1.045 1.059 1.003 1.026 0.933
hsa-miR-22*-4395412 1 1 1 1.25 1.041 0.95 0.95 0.948 1.118 1.191 1.022 0.967 0.964 0.864 0.92 1.080 1.005 1.060 0.916
hsa-miR-221*-4395207 1 1 1 2.033 0.986 1.327 1.17 1.105 1.35 1.485 0.791 1.085 0.998 0.646 1.145 1.449 1.208 1.120 0.930
hsa-miR-221-4373077 1 1 1 0.564 0.778 0.58 0.922 1.107 0.977 0.963 1.369 0.76 0.838 1.104 0.999 0.641 1.002 1.031 0.980
hsa-miR-222*-4395208 1 1 1 0.696 0.812 0.338 1.649 1.428 1.356 3.7 3.197 0.644 1.211 0.985 0.984 0.615 1.478 2.514 1.060
hsa-miR-222-4395387 1 1 1 0.853 1.369 0.892 1.07 1.195 1.045 1.269 1.237 0.858 0.924 1.056 0.911 1.038 1.103 1.121 0.964
hsa-miR-223*-4395209 1 1 1 1.127 0.925 0.904 1.014 0.934 1.011 1.124 0.942 0.894 0.991 0.843 1.061 0.985 0.986 0.987 0.965
hsa-miR-223-4395406 1 1 1 0.919 1.091 0.866 0.883 1.228 0.936 1.288 1.319 0.919 0.989 1.206 1.093 0.959 1.016 1.175 1.096
hsa-miR-24-4373072 1 1 1 0.811 0.881 0.821 0.703 0.811 0.823 0.916 0.867 0.779 0.841 0.773 0.885 0.838 0.779 0.854 0.833
hsa-miR-25-4373071 1 1 1 0.943 1.036 0.702 0.875 0.954 0.808 0.97 1.01 0.794 0.822 0.868 0.874 0.894 0.879 0.925 0.855
hsa-miR-26a-2*-4395226 1 1 1 0.296 0.001 0.376 1.034 1.034 1.276 0.497 0.38 0.988 0.876 0.806 1.281 0.224 1.115 0.622 0.988
hsa-miR-26a-4395166 1 1 1 0.792 1.132 0.983 0.909 1.075 0.907 0.916 1.165 0.871 0.872 0.998 1.07 0.969 0.964 0.984 0.980
hsa-miR-26b*-4395555 1 1 1 1.052 0.797 0.515 1.045 1.301 0.806 1.148 1.045 0.645 1.032 0.963 0.796 0.788 1.051 0.946 0.930
hsa-miR-26b-4395167 1 1 1 0.997 1.065 0.817 0.969 0.962 0.938 1.1 1.024 0.834 0.993 1.007 1.132 0.960 0.956 0.986 1.044
hsa-miR-27a*-4395556 1 1 1 1.321 1.234 0.866 0.909 0.979 0.788 2.764 2.515 1.084 1.013 1.211 1.109 1.140 0.892 2.121 1.111
hsa-miR-27a-4373287 1 1 1 0.919 1.018 0.686 1.083 1.123 0.857 1.35 1.383 0.923 1.132 1.114 1.099 0.874 1.021 1.219 1.115
hsa-miR-28-3p-4395557 1 1 1 0.972 1.005 0.847 0.949 0.978 0.863 0.917 0.962 0.822 0.945 0.887 0.952 0.941 0.930 0.900 0.928
hsa-miR-28-5p-4373067 1 1 1 0.814 1.054 1.106 0.868 0.943 0.955 0.811 1.002 0.879 0.776 0.868 1.051 0.991 0.922 0.897 0.898
hsa-miR-29a*-4395558 1 1 1 1.537 1.268 1.239 0.947 1.206 1.209 1.881 1.446 1.15 0.97 0.869 1.001 1.348 1.121 1.492 0.947
hsa-miR-29a-4395223 1 1 1 1.07 1.021 1.144 1.025 0.879 0.809 1.19 1.098 0.886 0.871 0.86 0.844 1.078 0.904 1.058 0.858
hsa-miR-29b-1*-4395276 1 1 1 1.998 1.111 3.112 0.896 0.465 0.768 4.911 2.446 2.274 0.601 0.887 0.733 2.074 0.710 3.210 0.740
hsa-miR-29b-2*-4395277 1 1 1 0.965 0.959 1.243 0.692 0.829 1.031 0.818 0.684 0.758 0.873 0.599 0.798 1.056 0.851 0.753 0.757
hsa-miR-29b-4373288 1 1 1 1.571 1.573 0.957 0.962 1.116 0.996 1.446 1.265 0.974 0.868 1.269 1.213 1.367 1.025 1.228 1.117
hsa-miR-29c*-4381131 1 1 1 1.043 1.107 0.75 0.994 1.312 1.003 0.866 1.066 0.765 0.855 1.01 0.9 0.967 1.103 0.899 0.922
hsa-miR-29c-4395171 1 1 1 1.212 1.082 0.964 1.011 0.879 1.118 1.342 0.927 1.081 0.94 0.904 1.147 1.086 1.003 1.117 0.997
hsa-miR-301a-4373064 1 1 1 1.241 1.134 0.599 1.146 1.173 0.849 1.413 1.289 0.847 1.194 1.085 0.959 0.991 1.056 1.183 1.079
hsa-miR-301b-4395503 1 1 1 0.766 1.061 0.779 0.899 1.153 0.986 0.902 1.398 0.872 0.852 0.996 0.959 0.869 1.013 1.057 0.936
hsa-miR-30a*-4373062 1 1 1 0.969 0.646 0.908 0.72 0.99 1.154 0.899 0.916 1.35 0.733 0.933 1.048 0.841 0.955 1.055 0.905
hsa-miR-30a-4373061 1 1 1 1.191 1.01 0.79 0.967 1.046 0.952 1.201 1.025 0.886 0.986 0.83 0.919 0.997 0.988 1.037 0.912
hsa-miR-30b-4373290 1 1 1 0.938 0.963 0.939 0.874 0.88 0.881 0.922 0.902 0.871 0.872 0.825 1.042 0.947 0.878 0.898 0.913
hsa-miR-30c-4373060 1 1 1 0.922 0.946 0.979 0.955 0.744 0.822 0.813 0.808 0.738 0.857 0.73 0.969 0.949 0.840 0.786 0.852
hsa-miR-30d*-4395416 1 1 1 0.67 0.631 0.615 0.845 1.238 0.922 0.807 0.869 0.827 0.892 0.962 0.973 0.639 1.002 0.834 0.942
MicroRNA expression in polarized macrophages
hsa-miR-30d-4373059 1 1 1 1.072 0.977 0.813 0.812 0.944 0.924 1.102 0.904 0.726 0.859 0.704 0.769 0.954 0.893 0.911 0.777
hsa-miR-30e*-4373057 1 1 1 1.009 0.975 0.699 0.963 1.178 0.88 1.123 1.015 0.725 0.944 0.969 0.858 0.894 1.007 0.954 0.924
hsa-miR-30e-4395334 1 1 1 1.299 1.2 0.808 1.08 1.293 0.983 1.331 1.104 0.862 1.046 1.079 0.951 1.102 1.119 1.099 1.025
hsa-miR-31-4395390 1 1 1 0.968 0.924 1.069 1.074 0.938 1.004 0.939 0.866 1.013 0.931 0.76 0.978 0.987 1.005 0.939 0.890
hsa-miR-320-4395388 1 1 1 0.944 1.073 0.873 0.995 0.987 0.925 1.067 1.061 0.859 1.096 1.011 1.126 0.963 0.969 0.996 1.078
hsa-miR-32-4395220 1 1 1 1.607 0.878 1.07 1.295 0.946 1.203 1.958 0.777 0.857 1.249 0.802 1.518 1.185 1.148 1.197 1.190
hsa-miR-324-3p-4395272 1 1 1 0.915 0.807 0.741 0.987 0.982 0.684 0.977 0.848 0.729 1.007 0.817 0.879 0.821 0.884 0.851 0.901
hsa-miR-324-5p-4373052 1 1 1 0.802 1.261 1.017 1.032 1.181 1.122 0.967 1.115 0.86 0.746 1.203 1.049 1.027 1.112 0.981 0.999
hsa-miR-328-4373049 1 1 1 0.791 1.049 0.78 0.948 1.092 0.89 0.881 0.966 0.75 0.906 0.964 0.923 0.873 0.977 0.866 0.931
hsa-miR-331-3p-4373046 1 1 1 1.063 0.994 0.794 1.144 1.029 0.717 1.025 0.994 0.68 1.057 0.821 0.795 0.950 0.963 0.900 0.891
hsa-miR-335-4373045 1 1 1 0.686 0.803 1.238 0.792 0.692 1.328 0.509 0.694 2.196 0.489 0.597 1.393 0.909 0.937 1.133 0.826
hsa-miR-338-3p-4395363 1 1 1 0.922 1.558 0.869 1.274 1.132 1.027 1.01 1.11 1.075 0.998 1.019 0.972 1.116 1.144 1.065 0.996
hsa-miR-339-3p-4395295 1 1 1 0.744 0.818 0.604 0.913 0.881 0.835 0.702 0.718 0.699 0.963 0.972 0.871 0.722 0.876 0.706 0.935
hsa-miR-33a*-4395247 1 1 1 1.022 1.209 0.827 0.762 1.026 0.934 0.934 0.946 0.798 0.726 1.075 0.727 1.019 0.907 0.893 0.843
hsa-miR-340*-4395370 1 1 1 1.052 0.988 0.712 0.975 1.088 0.948 0.991 0.945 0.76 0.94 0.888 1.015 0.917 1.004 0.899 0.948
hsa-miR-340-4395369 1 1 1 0.947 0.791 0.807 0.976 0.795 1.055 1.08 0.827 0.911 1.002 0.788 1.295 0.848 0.942 0.939 1.028
hsa-miR-342-3p-4395371 1 1 1 1.03 1.056 0.68 1.017 0.916 0.846 1.046 0.888 0.764 1.051 0.886 1.012 0.922 0.926 0.899 0.983
hsa-miR-345-4395297 1 1 1 0.653 0.961 0.655 0.869 1.041 0.793 0.739 1.033 0.704 0.809 1.071 0.885 0.756 0.901 0.825 0.922
hsa-miR-34a*-4395427 1 1 1 1 1.015 0.818 0.829 1.123 0.984 0.97 0.883 0.851 1.018 1.016 1.062 0.944 0.979 0.901 1.032
hsa-miR-34a-4395168 1 1 1 0.958 1.184 0.888 0.98 1.087 0.849 1.078 1.071 0.843 0.881 0.975 0.914 1.010 0.972 0.997 0.923
hsa-miR-362-3p-4395228 1 1 1 1.012 1.16 0.908 0.906 1.103 1.042 1.307 0.952 0.996 0.864 0.965 1.236 1.027 1.017 1.085 1.022
hsa-miR-362-5p-4378092 1 1 1 0.781 0.922 0.778 0.806 0.843 0.89 0.715 0.891 0.808 0.803 0.893 1.046 0.827 0.846 0.805 0.914
hsa-miR-363-4378090 1 1 1 1.121 1.18 0.968 1.086 1.049 1.33 0.998 0.95 1.028 0.953 0.78 1.224 1.090 1.155 0.992 0.986
hsa-miR-365-4373194 1 1 1 0.865 0.912 0.674 0.841 0.915 0.819 1.103 0.91 0.745 0.866 0.771 0.943 0.817 0.858 0.919 0.860
hsa-miR-374a*-4395236 1 1 1 1.572 1.229 0.683 1.041 1.034 0.919 1.201 0.614 0.719 1.287 0.903 1.14 1.161 0.998 0.845 1.110
hsa-miR-374a-4373028 1 1 1 0.822 0.974 0.853 0.847 0.909 1.028 0.833 0.928 0.927 0.915 0.879 1.161 0.883 0.928 0.896 0.985
hsa-miR-374b*-4395502 1 1 1 0.678 0.516 2.32 1.442 1.682 4.971 0.613 0.453 4.45 0.413 1.172 4.644 1.171 2.698 1.839 2.076
hsa-miR-374b-4381045 1 1 1 0.752 1.166 0.768 0.876 1.117 0.907 0.821 1.093 0.846 0.978 1.127 1.135 0.895 0.967 0.920 1.080
hsa-miR-376a-4373026 1 1 1 0.795 0.759 0.919 1.056 0.935 0.994 0.915 0.542 0.964 0.779 0.725 1.035 0.824 0.995 0.807 0.846
hsa-miR-376c-4395233 1 1 1 0.847 1.037 0.743 0.68 0.895 1.055 1.016 0.908 0.946 1.067 0.815 0.954 0.876 0.877 0.957 0.945
hsa-miR-378*-4373024 1 1 1 1.048 0.867 0.888 0.886 1.384 1.153 1.092 1.023 1.032 0.891 0.954 1.125 0.934 1.141 1.049 0.990
hsa-miR-378-4395354 1 1 1 1.176 0.965 0.836 1.041 1.291 0.996 1.158 1.041 0.768 1.001 0.93 0.868 0.992 1.109 0.989 0.933
hsa-miR-409-3p-4395443 1 1 1 0.837 0.957 1.115 0.754 0.611 1.092 1.37 1.05 1.734 1.059 0.629 0.959 0.970 0.819 1.385 0.882
hsa-miR-411-4381013 1 1 1 3.127 0.742 0.775 1.014 0.832 0.805 0.867 0.92 1.099 1.874 0.845 0.62 1.548 0.884 0.962 1.113
MicroRNA expression in polarized macrophages
hsa-miR-422a-4395408 1 1 1 0.554 0.675 0.667 0.851 0.954 0.635 0.718 0.899 0.548 0.73 0.954 0.844 0.632 0.813 0.722 0.843
hsa-miR-424*-4395420 1 1 1 0.989 0.741 1.383 1.337 0.767 0.526 1.162 1.115 1.651 1.083 0.92 1.473 1.038 0.877 1.309 1.159
hsa-miR-424-4373201 1 1 1 1.184 1.18 1.107 1.291 1.073 1.046 1.214 1.157 0.891 0.88 0.909 0.855 1.157 1.137 1.087 0.881
hsa-miR-425*-4395413 1 1 1 0.794 1.068 0.629 0.781 1.406 1.02 0.829 1.243 0.701 0.848 1.066 0.85 0.830 1.069 0.924 0.921
hsa-miR-429-4373203 1 1 1 0.794 0.644 0.812 0.928 1.108 0.983 0.875 0.937 0.849 0.78 0.581 1.021 0.750 1.006 0.887 0.794
hsa-miR-449a-4373207 1 1 1 1.005 1.332 1.169 0.95 1.734 0.927 1.047 1.542 0.968 0.707 1.374 0.665 1.169 1.204 1.186 0.915
hsa-miR-449b-4381011 1 1 1 1.32 1.715 1.149 0.957 0.808 0.742 1.524 1.35 0.963 1.068 0.779 0.94 1.395 0.836 1.279 0.929
hsa-miR-450a-4395414 1 1 1 0.786 1.244 0.84 0.795 0.963 0.729 0.7 1.292 0.793 0.843 1.161 0.89 0.957 0.829 0.928 0.965
hsa-miR-451-4373360 1 1 1 0.97 1.114 1.102 1.003 1.481 1.207 0.678 1.424 1.252 0.86 1.282 0.828 1.062 1.230 1.118 0.990
hsa-miR-454*-4395185 1 1 1 1.351 0.703 0.753 1.043 0.895 0.993 1.312 0.831 0.705 1.088 0.791 0.901 0.936 0.977 0.949 0.927
hsa-miR-454-4395434 1 1 1 0.843 1.057 0.756 0.936 0.897 0.793 0.958 0.964 0.787 1.014 0.966 0.958 0.885 0.875 0.903 0.979
hsa-miR-483-5p-4395449 1 1 1 0.484 0.898 0.527 0.66 1.22 0.884 1.039 1.711 1.297 0.853 1.26 0.958 0.636 0.921 1.349 1.024
hsa-miR-484-4381032 1 1 1 0.838 0.879 0.723 0.934 0.845 0.715 0.994 0.825 0.712 0.891 0.866 0.777 0.813 0.831 0.844 0.845
hsa-miR-487b-4378102 1 1 1 0.85 1.336 0.932 0.765 2.231 0.584 0.457 2.281 1.601 0.959 1 1.385 1.039 1.193 1.446 1.115
hsa-miR-491-5p-4381053 1 1 1 0.87 0.986 0.962 0.899 0.873 0.973 0.892 0.976 0.893 0.887 0.925 1.06 0.939 0.915 0.920 0.957
hsa-miR-494-4395476 1 1 1 0.92 1.249 1.165 0.825 0.984 0.96 0.899 2.023 0.973 0.597 2.814 0.993 1.111 0.923 1.298 1.468
hsa-miR-495-4381078 1 1 1 0.83 2.398 2.471 0.618 3.683 1.728 0.684 1.958 2.486 0.871 1.869 2.435 1.900 2.010 1.709 1.725
hsa-miR-500*-4373225 1 1 1 0.938 0.875 0.894 1.022 0.888 1.584 0.641 0.678 0.56 0.927 1.05 1.124 0.902 1.165 0.626 1.034
hsa-miR-500-4395539 1 1 1 0.989 1.299 0.706 1.118 1.177 0.767 1.094 1.289 0.87 1.027 1.057 0.882 0.998 1.021 1.084 0.989
hsa-miR-502-3p-4395194 1 1 1 0.98 1.16 1.049 1.088 1.013 1.011 0.969 1.109 0.939 0.813 0.952 1.168 1.063 1.037 1.006 0.978
hsa-miR-502-5p-4373227 1 1 1 0.986 1.339 0.831 0.912 1.078 1.118 1.111 1.126 0.839 0.971 0.947 1.403 1.052 1.036 1.025 1.107
hsa-miR-503-4373228 1 1 1 0.96 1.285 1.649 0.929 1.957 1.287 0.875 1.589 1.32 0.872 1.706 1.404 1.298 1.391 1.261 1.327
hsa-miR-505*-4395198 1 1 1 1.028 1.136 0.773 0.808 1.051 0.959 0.822 0.96 0.823 0.886 0.84 0.91 0.979 0.939 0.868 0.879
hsa-miR-505-4395200 1 1 1 1.186 0.927 0.599 1.08 0.856 0.736 1.443 1.136 0.713 1.152 0.797 0.893 0.904 0.891 1.097 0.947
hsa-miR-509-3p-4395347 1 1 1 0.965 1.987 1.381 1.272 1.961 0.597 0.951 1.343 1.473 0.983 2.081 0.848 1.444 1.277 1.256 1.304
hsa-miR-511-4373236 1 1 1 1.024 1.049 0.694 1.176 1.125 0.79 1.065 1.056 0.728 1.062 0.967 0.774 0.922 1.030 0.950 0.934
hsa-miR-516a-3p-4373183 1 1 1 0.557 2.163 1.237 1.23 1.946 1.435 1.169 0.8 1.111 1.341 3.01 1.313 1.319 1.537 1.027 1.888
hsa-miR-520c-3p-4395511 1 1 1 1.958 1.159 0.993 0.856 1.209 1.359 1.025 0.559 0.588 1.285 0.789 1.226 1.370 1.141 0.724 1.100
hsa-miR-532-3p-4395466 1 1 1 0.834 1.118 0.829 0.901 1.013 0.764 0.809 1.02 0.704 0.781 0.903 0.851 0.927 0.893 0.844 0.845
hsa-miR-532-5p-4380928 1 1 1 0.885 1.09 0.756 0.942 1.083 0.81 0.96 1.141 0.729 1.022 0.991 0.873 0.910 0.945 0.943 0.962
hsa-miR-542-3p-4378101 1 1 1 0.926 1.059 0.635 0.892 1.191 1.898 0.937 1.183 1.387 0.752 0.863 1.492 0.873 1.327 1.169 1.036
hsa-miR-545*-4395377 1 1 1 0.763 0.912 0.567 0.647 0.787 0.965 1.028 0.542 0.755 0.868 0.941 1.087 0.747 0.800 0.775 0.965
hsa-miR-545-4395378 1 1 1 0.833 1.822 1.297 1.144 1.552 1.167 1.228 1.344 1.233 0.874 1.636 1.476 1.317 1.288 1.268 1.329
hsa-miR-548c-5p-4395540 1 1 1 1.387 0.689 1.024 3.308 1.212 1.31 2.713 1.08 1.339 2.859 1.01 1.367 1.033 1.943 1.711 1.745
MicroRNA expression in polarized macrophages
hsa-miR-565-4380942 1 1 1 1.409 1.167 1.638 1.139 0.829 1.57 1.059 0.892 1.309 0.784 0.978 1.624 1.405 1.179 1.087 1.129
hsa-miR-572-4381017 1 1 1 0.61 0.765 2.088 0.799 1.389 2.213 0.518 0.546 2.119 0.602 0.599 1.892 1.154 1.467 1.061 1.031
hsa-miR-574-3p-4395460 1 1 1 0.852 1.054 0.862 0.967 1.065 0.851 0.932 1.189 0.973 0.876 0.955 0.971 0.923 0.961 1.031 0.934
hsa-miR-576-3p-4395462 1 1 1 0.862 0.786 0.93 1.037 0.803 1.451 1.128 0.745 1.073 1.351 0.797 1.474 0.859 1.097 0.982 1.207
hsa-miR-579-4395509 1 1 1 1.049 1.251 0.941 1.002 0.821 0.956 0.968 1.158 0.826 0.891 1.005 0.974 1.080 0.926 0.984 0.957
hsa-miR-589*-4380953 1 1 1 0.966 0.493 0.869 0.838 0.591 0.937 0.9 0.64 1.147 0.904 0.406 1.347 0.776 0.789 0.896 0.886
hsa-miR-589-4395520 1 1 1 0.647 0.467 0.767 1.146 0.705 0.663 2.004 0.612 0.929 1.024 0.599 1.604 0.627 0.838 1.182 1.076
hsa-miR-590-5p-4395176 1 1 1 1.084 1.272 0.8 1.161 1.188 0.92 1.385 1.092 0.905 1.149 1.201 1.28 1.052 1.090 1.127 1.210
hsa-miR-597-4380960 1 1 1 1.151 1.002 1.018 1.434 1.329 0.915 1.135 1.253 0.803 1.058 1.142 1.116 1.057 1.226 1.064 1.105
hsa-miR-598-4395179 1 1 1 0.997 0.918 0.883 0.971 1.042 0.853 1.026 0.919 0.766 1.136 1.027 1.042 0.933 0.955 0.904 1.068
hsa-miR-601-4380965 1 1 1 0.81 0.994 0.946 0.719 1.164 1.359 1.106 1.27 1.374 1.005 1.492 1.166 0.917 1.081 1.250 1.221
hsa-miR-616*-4380992 1 1 1 1.117 0.994 0.713 1.017 1.004 0.753 1.054 1.034 0.641 0.865 0.938 0.913 0.941 0.925 0.910 0.905
hsa-miR-618-4380996 1 1 1 0.758 0.624 0.489 0.913 0.525 0.332 0.684 0.697 0.828 1.007 0.663 0.581 0.624 0.590 0.736 0.750
hsa-miR-624*-4380964 1 1 1 1.842 0.73 1.27 1.096 0.878 1.201 1.501 1.258 0.88 0.64 0.575 0.63 1.281 1.058 1.213 0.615
hsa-miR-625*-4395543 1 1 1 0.957 0.861 1.094 1.071 0.946 0.987 0.933 0.837 1.032 0.941 1.024 1.137 0.971 1.001 0.934 1.034
hsa-miR-625-4395542 1 1 1 0.679 0.928 1.022 0.837 0.942 0.922 0.778 0.889 0.805 0.96 0.984 1.039 0.876 0.900 0.824 0.994
hsa-miR-627-4380967 1 1 1 0.469 1.548 0.797 0.675 1.482 1.34 0.748 1.393 0.733 0.369 1.269 1.518 0.938 1.166 0.958 1.052
hsa-miR-628-3p-4395545 1 1 1 0.883 1.016 0.793 0.888 1.102 0.941 0.766 1.047 0.816 0.991 1.154 0.951 0.897 0.977 0.876 1.032
hsa-miR-628-5p-4395544 1 1 1 0.834 1.073 0.777 0.951 1.065 0.751 0.853 0.895 0.756 1.119 1.142 0.858 0.895 0.922 0.835 1.040
hsa-miR-629*-4380969 1 1 1 0.993 0.792 0.68 0.881 0.862 1.101 0.892 0.876 1.007 0.997 0.727 0.858 0.822 0.948 0.925 0.861
hsa-miR-629-4395547 1 1 1 1.28 1.131 0.728 1.365 0.952 0.82 1.182 1.26 0.793 1.474 1.074 1.077 1.046 1.046 1.078 1.208
hsa-miR-636-4395199 1 1 1 1.279 1.347 0.649 1.266 0.804 0.911 1.254 1.288 0.83 1.098 0.764 1.228 1.092 0.994 1.124 1.030
hsa-miR-642-4380995 1 1 1 0.948 1.194 0.921 0.968 0.992 1.062 1.26 1.037 1.08 0.844 0.925 1.204 1.021 1.007 1.126 0.991
hsa-miR-651-4381007 1 1 1 0.857 1.171 0.829 0.812 0.864 1.093 0.89 1.197 1.376 1.097 1.088 0.952 0.952 0.923 1.154 1.046
hsa-miR-652-4395463 1 1 1 0.947 1.008 0.89 1.074 1.032 0.848 1.092 1.023 0.8 0.938 0.983 0.97 0.948 0.985 0.972 0.964
hsa-miR-660-4380925 1 1 1 0.989 1.252 0.814 1.119 1.093 0.914 0.961 1.217 0.923 0.921 1.127 1.028 1.018 1.042 1.034 1.025
hsa-miR-671-3p-4395433 1 1 1 0.596 0.505 0.599 1.03 0.857 0.833 0.651 0.57 0.602 1.105 0.795 0.994 0.567 0.907 0.608 0.965
hsa-miR-708-4395452 1 1 1 0.997 1.329 0.85 0.979 1.248 0.823 1.119 1.276 1.042 1.109 1.244 0.894 1.059 1.017 1.146 1.082
hsa-miR-7-1*-4381118 1 1 1 0.961 1.053 1.196 0.941 0.914 0.924 1.132 1.108 0.87 0.861 0.943 0.857 1.070 0.926 1.037 0.887
hsa-miR-7-4378130 1 1 1 1.273 1.221 1.088 0.981 1.011 0.992 1.258 0.878 1.132 1.043 0.813 0.867 1.194 0.995 1.089 0.908
hsa-miR-744*-4395436 1 1 1 0.915 0.571 0.726 0.792 1.358 0.73 0.978 0.518 0.767 0.599 0.503 0.675 0.737 0.960 0.754 0.592
hsa-miR-744-4395435 1 1 1 0.853 0.932 0.841 0.913 0.897 0.854 0.943 1.046 0.864 0.886 0.908 0.884 0.875 0.888 0.951 0.893
hsa-miR-766-4395177 1 1 1 0.816 0.993 0.901 0.942 1.071 1.029 0.917 1.18 0.855 1.07 1.224 0.954 0.903 1.014 0.984 1.083
hsa-miR-768-3p-4395188 1 1 1 1.126 1.075 0.985 1.015 1.267 1.148 1.165 1.219 1.09 0.928 1 1.006 1.062 1.143 1.158 0.978
MicroRNA expression in polarized macrophages
hsa-miR-769-5p-4395186 1 1 1 0.872 0.93 0.933 1.06 1.064 1.091 0.87 0.96 0.836 1.001 1.01 1.013 0.912 1.072 0.889 1.008
hsa-miR-801-4395183 1 1 1 1.078 0.827 2.117 1.147 0.834 3.958 2.779 2.466 3.508 1.128 0.875 4.592 1.341 1.980 2.918 2.198
hsa-miR-875-5p-4395314 1 1 1 0.949 0.685 2.103 0.82 0.637 1.805 0.64 0.687 1.863 1.195 0.438 1.861 1.246 1.087 1.063 1.165
hsa-miR-877-4395402 1 1 1 1.195 1.007 0.842 0.96 1.117 0.969 0.965 0.889 0.749 1.117 1.074 0.95 1.015 1.015 0.868 1.047
hsa-miR-885-5p-4395407 1 1 1 0.852 1.25 0.625 1.058 0.916 0.767 1.017 1.067 0.734 1.002 1.002 1.027 0.909 0.914 0.939 1.010
hsa-miR-886-5p-4395304 1 1 1 1.192 1.352 1.199 0.97 0.915 1.159 1.052 0.862 0.981 0.865 0.807 1.911 1.248 1.015 0.965 1.194
hsa-miR-9*-4395342 1 1 1 1.2 1.298 0.882 0.996 1.005 1.063 1.233 1.121 1.041 0.927 0.922 1.283 1.127 1.021 1.132 1.044
hsa-miR-92a-1*-4395248 1 1 1 2.048 0.901 0.917 1.495 1.463 1.856 1.2 0.69 1.123 1.106 0.587 1.107 1.289 1.605 1.004 0.933
hsa-miR-92a-4395169 1 1 1 1.159 1.109 1.01 1.061 0.939 0.971 0.98 0.932 0.899 0.963 0.809 0.899 1.093 0.990 0.937 0.890
hsa-miR-93*-4395250 1 1 1 0.902 1.009 0.904 0.989 1.18 1.057 1.02 1.009 1.015 0.932 0.969 0.98 0.938 1.075 1.015 0.960
hsa-miR-93-4373302 1 1 1 0.805 1.015 0.867 0.899 1.032 0.927 0.888 1.011 0.941 0.924 0.954 1.051 0.896 0.953 0.947 0.976
hsa-miR-941-4395294 1 1 1 0.854 1.257 0.48 1.052 1.049 1.056 0.561 1.06 0.374 0.745 1.192 0.935 0.864 1.052 0.665 0.957
hsa-miR-942-4395298 1 1 1 0.868 0.741 0.915 0.751 1.063 0.852 0.867 0.864 1.089 0.789 0.765 1.002 0.841 0.889 0.940 0.852
hsa-miR-9-4373285 1 1 1 0.718 1.148 1.219 0.696 0.94 1.069 0.752 1.027 1.094 0.615 0.776 0.961 1.028 0.902 0.958 0.784
hsa-miR-95-4373011 1 1 1 0.958 1.134 1.022 0.986 0.978 1.058 0.971 1.131 1.081 0.947 0.969 1.145 1.038 1.007 1.061 1.020
hsa-miR-99b*-4395307 1 1 1 0.911 1.143 0.879 0.79 1.278 0.756 1.442 1.207 0.581 1.115 1.25 0.77 0.978 0.941 1.077 1.045
Human MDMs were incubated in M1-, M2a-, M2b-, or M2c-polarizing conditions for 8 hours. RNA was collected and analyzed using a TaqMan Low Density Array from Applied Biosystems to determine miRNA expression. Data in the table indicate the fold change in expression of the indicated miRNA following exposure to polarizing treatment in each of three independent monocyte-derived macrophage (MDM) preparations. Changes in miRNA expression in treated relative to no treatment samples were calculated by the
Ct method, using RNU48 as an endogenous control. The mean fold change is indicated in the final 4 columns (n=3). D1 = MDM donor 1; D2 = MDM donor 2; D3 = MDM donor 3