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Secondary analyses of HSE data and linked health outcomes - an overview of work in progress
Dr Jennifer Mindell,
UCL (University College London)
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Linked HSE mortality data (2008)
• In 2008, some mortality data provided by ONS:oHSE 1994 – 2004oDeaths to March 2008
• Will not be archived or publicised until regular updates organised
• Released to a few named researchers by NatCen after detailed review by their Data Release Panel
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Published studies include:
Hamer M, Ingle L, Carroll S, Stamatakis E.
Physical Activity and Cardiovascular Mortality Risk: Possible Protective Mechanisms?
Med Sci Sports Exerc. 2011 Jun 8. [Epub ahead of print]
o HSE + SHeS datao average follow up 7.0y ± 3.1yo 446 deaths (213 CVD)
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Body mass index, waist circumference and waist-hip ratio: which is the better discriminator of cardiovascular disease mortality risk?
• Czernichow S, Kengne AP, Stamatakis E, Hamer M, Batty GD. Obes Rev. 2011 Apr 27. doi: 10.1111/j.1467-789X.2011.00879.x. [Epub ahead of print]
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Physical activity behaviour and coronary heart disease mortality among South Asian people in the UK: an observational longitudinal study.
Williams ED, Stamatakis E, Chandola T, Hamer M.
Heart. 2011;97(8):655-9. • HSE 1999 & 2004
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Adjusted HRs (with 95% CIs) for ethnicity on coronary heart disease mortality
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The combined influence of hypertension and common mental disorder on all-cause and cardiovascular disease mortality
Hamer M, Batty GD, Stamatakis E, Kivimaki M.
J Hypertens. 2010;28(12):2401-6.• HSE data• Hypertension has a stronger association with
total and CVD mortality in people with a GHQ-12 score of ≥ 4
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Linked HSE mortality data (2011)
• NatCen has just received the latest update of Mortality records from ONS, though some delay in IC implementing new procedures that will increase automated matching
• Some data will / may / probably be archived later in 2011
• More detailed data may be available from NatCen via their Data Release Panel
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HSE linked Hospital Episodes Statistics
• NatCen is in discussion with the NHS Information Centre about HES data:o what we can haveo how we will link thiso what we can or can't do with the data etc
• What will be available on the archive, what will be available from NatCen, what won’t be available - still being negotiated
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Linkage of multiple databases
Hamer M, Stamatakis E. Physical activity and mortality in men and women with diagnosed cardiovascular disease. Eur J Cardiovasc Prev Rehabil. 2009;16(2):156-60.
• Scottish Health Surveys (1995, 1998, 2003) • Linked to patient-based database of CVD hospital
admissions and deaths o 837 adults with clinically confirmed CVD at baselineo 175 diedo follow-up average 5.6y +/-3.1y
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Linkage of multiple databases
• Men and women with existing CVD who participate in moderate-to-vigorous activity for at least 20 min pw showed the lowest risks of all-cause mortality:o fully adjusted hazard ratio=0.32 (95% CI 0.16-0.65) for sporto fully adjusted hazard ratio=0.74 (0.53-1.04) for walking
• Similar associations observed for CVD mortality. • The physically active also showed
o ↓inflammatory risk markers o ↑ HDL cholesterol.
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Cancer data
• Cancer mortality• Incident cancer
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Diabetes, hyperglycaemia and cancer incidence and mortalityVanessa Gordon-Dseagu
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Preliminary results: Cancer among the HSE and SHeS cohort at baseline
Cancer among diabetic (%)
Cancer non-diabetic (%)
HSE 3.1 2.0SHeS 2.4 1.1
Total 3.0 (n=261)
1.8 (n=3,458)
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How do I access HSE mortality data?
• If people are interested in accessing this data they should contact Susan Nunn, the HSE Data Manager ([email protected]) who will oversee their application process.
• The application would ordinarily be:o reviewed by NatCen’s internal Data Release Panel,o probably by the NHS Information Centre o - and quite possibly ONS too.