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Risk factors of acute pancreatitis: An ethnic difference
2015/03/30
埔里基督教醫院不分科住院醫師
何御彰
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Introduction
Increasing incidence rate of acute pancreatitis 4 to 70 per 100,000 population
Pancreas 2014,43:1117-1122
Increases by an annual average of 1 to 5%Pancreas 2012,41:696-702
Risk factor of acute pancreatitis Cigarette smoking in Western countries
Am J Epidemiol 2008,168:932-937
Arch Intern Med 2008,168:649-656
Alcohol drinking in TaiwanPancreas 2014,43:1117-1122
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Introduction
Study from Australia Higher rate of alcohol-related acute pancreatitis
Aust J Rural Health 2001,9:134-137
The aim of the study To investigate the differences in risk factors between Taiwanese
aborigines and non-aborigines
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Materials and Methods
Participants Recruitment
Puli Christian Hospital (PCH) January, 2006 to December, 2014 International Classification of Diseases 577.0
Exclusion Re-admission Nationality other than Republic of China
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Materials and Methods
Demographic characteristics Age / Gender / Body mass index
Social habitus Alcohol drinking / Betel nut chewing / Cigarette smoking
Biochemical properties Amylase / Lipase / Triglyceride / Uric acid / Calcium
Risk factors Alcohol-related / Gallstone / Hypertriglyceridemia Distal CBD obstruction / Hypercalcemia / Unknown
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Materials and Methods
Statistical analysis Two tailed unpaired student’s t test
Age / BMI Amylase / Lipase / Triglyceride / Uric acid / Calcium
Pearson’s chi-squared test and Fisher’s exact test Gender Habitus Risk factor of acute pancreatitis
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Result
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Result
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Result
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Discussion
Demographic characteristics & Social habitus Aborigines
Younger Higher female-to-male ratio More habitus of alcohol drinking
Major issue of public health in Taiwanese aborigines More readily accessibility to alcohol Stress of marital life
Alcohol Clin Exp Res 1995,19:81-91
Soc Psychiatry Psychiatr Epidemiol 2013,48:955-963
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Discussion
Biochemical properties Aborigines
Higher uric acid level Possible explanation
More alcohol consumption More vulnerability of hyperuricemia at a genetic level
Am J Hum Genet 2004,75:498-503
Higher uric acid level in smoking patients with pancreatitisPrzegl Lek 2013,70:809-812
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Discussion
Risk factors Aborigines
More alcohol-related acute pancreatitis Culturally adapted intervention
Motivational care planningAust J Rural Health 2009,17:174-182
General practitioners trainingAust J Rural Health 2013,21:72-79
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Discussion
Limitation Inadequate information of alcohol drinking Lack of easily medical accessibility Critical condition with immediate referral Extensive risk factor surveys were not conducted for everyone
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Conclusion
Taiwanese aborigines are more susceptible to alcohol-related pancreatitis than non-aborigines.
The importance of public health education and effective strategy to prevent them from alcoholism cannot be overemphasized
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Thank you for your listening