2003 Fused pyrimidine derivatives

Fused pyrimidine derivativesR 0515 Rapid Analogue Synthesis of C-5 Substituted 1,2,3-Triazolo[1,5-a]quinazolines.

— Imino tosylate (III) is found to be a potential compound for the palladium-catalyzed cross-coupling with heteroaromatic stannanes as well as acetylene (VI) to give a variety of title compounds in good yields. Imino chloride (XIII) can be also employed in the coupling reaction but in most cases the yields are only modest. — (JONES*, P.; CHAMBERS, M.; Tetrahedron 58 (2002) 50, 9973-9981; Merck Sharp Dohme Res. Lab., Neurosci. Res. Cent., Harlow, Essex CM20 2QR, UK; Eng.) — Klein

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2003 Fused pyrimidine derivatives