Product Portfolio OverviewPartnering with you to drive discovery
Over 3500 biologically active recombinant and natural proteins spanning 35 species. Quality•Stringentqualitycontrolspecificationsforactivity,purity,
and endotoxin. • More citations than any other protein manufacturer.• Lot-to-lot consistency.• Unmatched customer support.
Selection•Cytokines,receptors,proteases,andenzymesformetabolism
and glycobiology research. •Tagstomeetneeds:His,Fc,Biotin,Avi,andmore.•Morethan10,000non-catalogproteinsavailable.• ProDots®Proteins:Eliminatealiquotingusinglyophilizedspheres
that dissolve instantly in culture.
GMP Cytokines and Growth Factors•Madespecificallyforcell-basedclinicalmanufacturing•ISO9001,ISO13485-certifiedfacility.•Animal-freemanufacturing•Focusonconsistency,safety,andsupplychain• Global experience
Custom Development• Experience with a wide range of protein classes• New proteins from scratch• RUO to GMP conversion for ex vivo clinical manufacturing•Formulationtomeetyourrequirements• Dedicated project managers
PROTEINS
Learn more | rndsystems.com/proteins
Over4,000highqualitychemicaltoolcompounds. GPCRLigands,EnzymeInhibitors,IonChannelModulators,FluorescentProbes&Dyes,CompoundLibraries
• Competitive Pricing. Highendproductspricedtomaximizeyourresearchbudget.
• Be at the Forefront of Research. Fromthelatestexclusivelylicensedresearchtoolstoestablishedbiochemical standards.
• Unrivaled Product Quality. Certifiedhighpurity,typicallygreaterthan99%asmeasured by HPLC.
• Fully Annotated Compounds The biological activity of all products is supported by peer- reviewed publications.
SMALLMOLECULES
Learn more | tocris.com»
Over155,000antibodies.• Confidence in Your Purchase. Ourantibodiesare100%guaranteedtoworkintheapplication and species listed.
• Unique Clones and Exclusive Antibodies. ManyofouruniquecloneshavebeenusedbyHLDAtoestablishCDnomenclatureandweofferover15,000antibodiesthatareavailable exclusively from us.
• Wide Selection of Conjugated Antibodies. Weofferover50,000antibodiesconjugatedtoatleast14complimentary colors.
• Monoclonal Antibody Panels Thousands of non-catalog monoclonal antibodies available now. Testthesepanelsinyourapplicationtofindtheclonethatproduces optimal results.
• Recombinant Antibody Conversion and Engineering Services Wehavegeneratedhundredsofrecombinantantibodies,aslistedin our catalog. Let our experts convert your hybridoma to an immortalizedrecombinantantibodyandevenengineermodificationssuchasspecies,isotype,andFcregions.
• Custom Antibody Development Generatecustommonoclonalorpolyclonalantibodies,fromimmunogendesigntopurifiedantibodyspecificityscreening, by partnering with our expert development team.
ANTIBODIES
Learn more | rndsystems.com/antibodies novusbio.com»
Experts in developing tools for advancing stem cell and 3-D cell culture. • We Have You Covered Throughisolation,differentiation,verification,andinvestigation,wehavetoolstomakeyourstemcell,organoid,and3-Dcellculturemoreefficientandreliable.
• Minimize Experimental Variability Reducing experimental variability saves time and allows for more confidentdataanalysis.Fromstemcelldifferentiationandverificationkitstoadvancedtoolsfororganoidand3-Dtissuegeneration,ourportfoliohelpsresearchersbuildconsistentandrobust cell culture models.
• Don’t Wait to Differentiate Ourall-in-onekitsforthedifferentiationofES/iPScells,HSCs,MSCs,andNSCsmakeworkingwithstemcellslookeasy.
• Evolve Your 3-D Models Stay at the forefront of 3-D cell culture by using our organoid reagentguideortryingMimEX™TissueModelSystems,aninnovative technology for generating accessible 3-D epithelial tissue in vitro.
STEMCELLAND3-DCULTUREMODELS
Learn more | rndsystems.com/stemcells»
Expedite your research. Partnering with our industry-renowned product development and biomarker testing scientists to deliver unique reagents and reliable data.
• Custom Protein & Antibody Generation Our recombinant technologies provide gram quantities of consistent proteins and antibodies required for diagnostic and therapeutic reagent development.
• Assay Development R&DSystemshasover20yearsofexperiencedeveloping,optimizing,andvalidatingimmunoassaykitsandLuminex® assays to ensure the highest level of performance in analytequantification.
• Biomarker & Bioactivity Testing Services Entrusting our experts with your clinical study samples ensures accurateresultsthatarereturnedinatimely,efficient,regulatorycompliant,andconfidentialmanner.
CUSTOMPRODUCTS&CONTRACTSERVICES
Learn more | rndsystems.com/custom»
CELLCULTUREESSENTIALS
Growhealthyandrobustcellswithourfullcellcultureworkflowportfolio.• Culture with Confidence Fromcellculturesubstratesandmediasupplementstodifferentiationandcellbehaviorkits,ourtoolsforcellculturearedesigned to ensure that in vitro and ex vivo experiments will perform optimally.
• Cell Culture Basics by the Best Withtheadditionofhigh-qualityAtlantaBiologicals™FetalBovineSerum,animalserum,basemedia,andbalancedsaltsolutionsitiseasierthaneverforresearcherstogeneratemediaoptimized for their cell of choice.
• Optimized Kits and Media Supplements Withhigh-qualitygrowthfactors,cytokines,smallmolecules,andmatrixcomponentsatourdisposal,we’vedesignedspecialtymediaandkitsforthegrowthanddifferentiationofimmunecells,braincells,stemcells,andmore.
Learn more | rndsystems.com/cellculture»
Ubiquitin RelatedDiscovery ToolsInhibitors
KitsDUBs
Ubiquitin and Ubiquitin-like Modifiers
Animal-Free™
ProDots™ ProteinsGMP-Grade
High Bioactivity
Custom ProteinDevelopment
High Purity
Cell Differentiation Kits
Lot-to-Lot ConsistencyBulk AvailableProteins
Largest Offering of Bioactive Proteins
Surveyor™ ICImmunoassays
Parameter™ Kits
ELISpot
Fluorokine® E Activity Assay
Cell-Based ELISAs
Quantikine® HS
Quantikine® IVD
QuantiGlo®
DuoSet® Kits
Quantikine® ELISAs
DuoSet® IC Kits
DevelopmentModules
Complete Kits
ELISAsSetting the Industry
Gold Standard
RNAscope® Probes
Reagent Kits
Software & Quality Controls
Hybridization Systems
RNA ISHDetect Biomarkers
with Precision
Receptor Agonistsand Antagonists
Enzyme Inhibitors
Caged Compounds
Fluorescent Probes
Peptides
Compound Libraries
Ion Channel Modulators
Small MoleculesHigh Performance
Life Science Reagents
Growth Factors
Small Molecules
Gastrointestinal
Airway
Liver SkinCell ScaffoldingMatrices
N21-MAX and N-2 Supplements
Organoids
MimEX™ Tissue Model Systems
Mesenchymal
Hematopoietic
Neural
Differentiation Kits
Pluripotency Verification Kits
iMEF Cells
ES/iPS Cells
Stem Cells &3-D Models
Culture. Differentiate.Verify. Investigate.
FLEXMAP™ 3DLuminex®
MAGPIX™
Luminex 200™
Peggy Sue
Simple Western
SimplePlex
ProteinSimple®
Wes™
EllaMilo™
Maurice™
Micro-FlowImaging
FluorChemImagers andAlphaImagers
Sally Sue
InstrumentsInnovative Multi-analyte
Detection Platforms
SecondaryAntibodies
ISO Controls
ApplicationValidation
Conjugated
NorthernLights™
MultipleFluorochromes
Biotin
WB
ELISA
B/N
Simple Western™
IHC/ICC
IF
CD
FCChIP
IP
AP
AntibodiesOver 155,000 Available
Media Supplements
Cell Behavior Assays
Migration
Invasion
ProliferationApoptosis
DNA Damage
Fetal Bovine Serum
Balanced Salt Solutions
Atlanta Biologicals™ by R&D Systems
Antibiotics/Antimycotics
Cultrex® ECM and Basement Membrane Extracts
Cytokines
Growth FactorsSpecialty Media
Base Media
Grow Healthy & Robust Cells
Cell CultureEssentials
Luminex Assay Performance
Measure 100 AnalytesSimultaneously
Magnetic and Polystyrene Beads
Most Flexible Most Accurate
ConfigureYour Panel
Luminex®
Assays
Zebrafish
MultipleSpecies
Mouse
Human
Canine
Viral
Drosophila
Feline
Porcine
Rat
Bovine
No SpecializedEquipment Needed
Proteome Profiler™
More than 100 Analytes at Once
Membrane-Based
ProteomeProfiler™ ArraysEach Analyte Extensively
Tested for Specificity
Single Cell Western Lateral FlowKnockout/Knockdown ValidatedCyTOF-ready
Ubiquitin RelatedDiscovery ToolsInhibitors
KitsDUBs
Ubiquitin and Ubiquitin-like Modifiers
Animal-Free™
ProDots™ ProteinsGMP-Grade
High Bioactivity
Custom ProteinDevelopment
High Purity
Cell Differentiation Kits
Lot-to-Lot ConsistencyBulk AvailableProteins
Largest Offering of Bioactive Proteins
Surveyor™ ICImmunoassays
Parameter™ Kits
ELISpot
Fluorokine® E Activity Assay
Cell-Based ELISAs
Quantikine® HS
Quantikine® IVD
QuantiGlo®
DuoSet® Kits
Quantikine® ELISAs
DuoSet® IC Kits
DevelopmentModules
Complete Kits
ELISAsSetting the Industry
Gold Standard
RNAscope® Probes
Reagent Kits
Software & Quality Controls
Hybridization Systems
RNA ISHDetect Biomarkers
with Precision
Receptor Agonistsand Antagonists
Enzyme Inhibitors
Caged Compounds
Fluorescent Probes
Peptides
Compound Libraries
Ion Channel Modulators
Small MoleculesHigh Performance
Life Science Reagents
Growth Factors
Small Molecules
Gastrointestinal
Airway
Liver SkinCell ScaffoldingMatrices
N21-MAX and N-2 Supplements
Organoids
MimEX™ Tissue Model Systems
Mesenchymal
Hematopoietic
Neural
Differentiation Kits
Pluripotency Verification Kits
iMEF Cells
ES/iPS Cells
Stem Cells &3-D Models
Culture. Differentiate.Verify. Investigate.
FLEXMAP™ 3DLuminex®
MAGPIX™
Luminex 200™
Peggy Sue
Simple Western
SimplePlex
ProteinSimple®
Wes™
EllaMilo™
Maurice™
Micro-FlowImaging
FluorChemImagers andAlphaImagers
Sally Sue
InstrumentsInnovative Multi-analyte
Detection Platforms
SecondaryAntibodies
ISO Controls
ApplicationValidation
Conjugated
NorthernLights™
MultipleFluorochromes
Biotin
WB
ELISA
B/N
Simple Western™
IHC/ICC
IF
CD
FCChIP
IP
AP
AntibodiesOver 155,000 Available
Media Supplements
Cell Behavior Assays
Migration
Invasion
ProliferationApoptosis
DNA Damage
Fetal Bovine Serum
Balanced Salt Solutions
Atlanta Biologicals™ by R&D Systems
Antibiotics/Antimycotics
Cultrex® ECM and Basement Membrane Extracts
Cytokines
Growth FactorsSpecialty Media
Base Media
Grow Healthy & Robust Cells
Cell CultureEssentials
Luminex Assay Performance
Measure 100 AnalytesSimultaneously
Magnetic and Polystyrene Beads
Most Flexible Most Accurate
ConfigureYour Panel
Luminex®
Assays
Zebrafish
MultipleSpecies
Mouse
Human
Canine
Viral
Drosophila
Feline
Porcine
Rat
Bovine
No SpecializedEquipment Needed
Proteome Profiler™
More than 100 Analytes at Once
Membrane-Based
ProteomeProfiler™ ArraysEach Analyte Extensively
Tested for Specificity
Single Cell Western Lateral FlowKnockout/Knockdown ValidatedCyTOF-ready
Choose from Standard or High Performance• High Perfomance. LuminexHighPerformanceAssaysarethemostaccurateandprecise bead-based multiplex assays for simultaneously measuring upto45analytesfromcustomizablepanelsinqualifiedcomplexmatrices. You choose if you prefer us to mix the beads or if you want to do it yourself.
• Uniquely Flexible Assay Options. OurStandardLuminexAssaysaretheonlyassaysonthemarketina premixed format where you choose from a large selection of analytes to create your own unique panel of 50 analytes which are then fully quality controlled for compatibility before shipment.
• Results You Can Trust. We are the immunoassay experts with 30 years of experience using our internally manufactured antibodies in developing assay conditions and diluents to protect against false positives.
• Complete Your Panel of Analytes. Take advantage of our massive in-house collection of antibodies and proteins. Complete your panel with a custom development order.
LUMINEX®ASSAYS
Learn more | rndsystems.com/luminex»
700analytesspanning12species.• Legendary Performance.
Quantikine®ELISAkitssettheindustrygoldstandardinperformance and reproducibility. Results today can be compared to last month or even last year.
• Confidence with Controls. Our assays have available controls with assigned ranges which guarantee performance.
• Economical Alternatives. Our DuoSet® and DuoSet®Intracellular(IC)ELISADevelopmentSystems provide the best signal-to-noise ratio for value- conscious labs.
We outperform the competition. • Be Confident in the Data. Small,crispspotsallforeasiermoreaccuratequantitationand the largest dynamic range (number of detectable spots/well) on the market.
• Detect Low Frequency Responses. Our kits can measure responses with frequencies well below 1 in 100,000cells–upto20%moresensitivethanourcompetition.
• Be Assured the Kit Worked. We are the only company that provides recombinant protein positive controls.
ELISAs ELISpot
Learn more | rndsystems.com/elispotLearn more | rndsystems.com/elisas» »
Cast a wide net and stretch your dollar.• Can You Run a Western Blot? Iftheanswerisyes,thenyouhavealltheequipmentyouneedtouse our antibody arrays.
• User-Friendly Design. Eacharrayisstampedwithanidentificationnumberforeasyrecordkeeping and contains reference spots in three corners for orientation purposes.
• Cost-Effective Screening. Each array offers a quick and inexpensive analysis of many analytessimultaneously,inlesstimethanittakestoperformaWestern blot.
ANTIBODYARRAYS
Learn more | rndsystems.com/proteomeprofiler»
Luminex®
MAGPIX® System•Simple,compact,affordable,andabletomultiplexupto50analytesusingmagneticbeads
with a read time of just 60 minutes for a 96-well plate.
Luminex® 200™
•Multiplexupto100analytesusingpolystyrenebeadsor80analytesusingmagneticbeadswithareadtimeofonly45minutesfora96-wellplate.
FLEXMAP 3D® •Themostadvancedandversatilemultiplexingplatform.Compatiblewith96-and384-wellplates,itreadsupto500beadregionsinboththepolystyreneandmagneticformatsandis compatible with front-end automation systems making this the ideal platform for high-throughput applications.
INSTRUMENTATION
ProteinSimple®
Ella runs Simple Plex™ assays.•Runupto4immunoassaysfrom25uLofsample,withnocross-reactivity.
•Setupsamplesin10minutes,getdatain1hour.
•Gethighlysensitiveresultsat<10%CV.
•Choosefromupto150validatedtargets,fromcytokinestoPD-L1.
Wes™, Peggy Sue™ and Sally Sue™ run Simple Western™ assays.•Separationbycapillaryelectrophoresisandimmunodetectionofproteinsfrom2–440kDaorbycharge(IEF).
•Nogel,blotsandminimalhands-onarerequired.
• Sample to results in as little as 3 hours with Wes.
•Quantifiableandreproducibledata.
Milo™
•MilodoesSingle-CellWesternstomeasureproteinexpressionin~1,000singlecellsinasingle run.
•Multiplextomeasure~4proteinsineachsingle-cell.
•Useoff-the-shelf,Western-validatedantibodiestomeasureintracellularproteinsortargetsthatdon'thavegoodflowantibodies.
•Identifycellsubtypesthataren’tvisibleintraditionalWesternsorgetdirectproteinvalidationofyoursingle-cellRNAresults.
Maurice• Next generation analytical platform for protein-based biopharmaceutical products.
•cIEForCE-SDSdatainasnap.
•NovelnativefluorescencedetectionprovidesincreasedcIEFsensitivity.
• Proprietary ready-to-use cartridge for unparalleled ease-of-use.
Micro-Flow Imaging™ (MFI)• Image based analysis for sub-visible particles.
• Highly sensitive detection for translucent particles.
• Morphological measurements to distinguish different particle populations.
• Walk-away automation for up to 90 samples.
FluorChem™ Imagers and AlphaImagers. •Highqualitydigitalimagingandanalysisforprotein/DNAgelsandWesternblots.
•Coverawiderangeofapplications,fromcolonycountingtomulticolorfluorescentWesterns.
•Easy-to-use,versatilesystemswithpowerfulanalysissoftware.
• Numerous excitation and emission options.
Luminex®MAGPIX™
Luminex®200™
Luminex®FLEXMAP™
MiloTM
iCEsystems:ImagedcIEF&CE-SDS
Ella
WesTM
R&D Systems develops and manufactures high-quality proteins andservesasaworldleaderinimmunoassays.R&DSystemsalsoproducesqualityantibodies,antibodyarrays,stemcellandcellcultureproducts,andcellselectionanddetectionproducts,servingthe life science and diagnostics industry. rndsystems.com
Novus Biologicals licenses,manufactures,andmarketsantibodiestoover20,000uniquetargetstosupportawidearrayofresearchareas.Novusisbuiltonhonesty,collaborationandstrongrelationships and continues to provide quality tools that accelerate research.Everyproductisbackedbyour100%guarantee. novusbio.com.
Tocris Bioscience is a leading supplier of innovative high performance life science research reagents. The Tocris range of small molecules and peptides represents a unique collection of novel andexclusiveresearchtools,includingGPCRligands,ionchannelmodulators,enzymeinhibitors,cagedcompounds,fluorescentprobes,andscreeninglibraries. tocris.com
ProteinSimple AtProteinSimplewe’rechangingthewayresearchersanalyzeproteins.Ourinnovativeproductportfoliohelpsresearchersrevealnewinsightintoproteins,advancingtheir understanding of protein function. We enable cutting-edge research to uncover the role of proteins in disease and provide novel approachestodevelopandanalyzeprotein-basedtherapeutics.Weempower you to make your next discovery by eliminating common proteinanalysisworkflowchallenges. proteinsimple.com
Advanced Cell Diagnostics (ACD) enables single day manual and automated gene expression analysis by providing optimizedsingeandmultiplexchromogenicandfluorescenceassaykits,>15,000off-the-shelftargetprobesandpharmaassayservicesbasedonRNAscope®technology,themostadvancedRNAin situ hybridization(ISH)assaywhichallowsresearcherstovisualizegenesexpressedatasinglemoleculeRNAsensitivity,localizewheretheyareexpressed,andquantifythelevelofexpression.Enablingacademicresearch,drugdevelopment,diagnosticandCDxassays,ACD’scoreapplicationsincludecancer,immune-oncology,neuroscience,Infectiousdisease,stemcellresearchandgenetherapy.RNAscopehasreached1000peerreviewedpublicationsinless than 6 years. acdbio.com
BR_ProductPortfolio_31509
[email protected]/find-us/distributorsTEL+16123792956North AmericaTEL8003437475Europe | Middle East | AfricaTEL+44(0)[email protected]+86(21)52380373
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