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National Science FoundationOverview and
Funding Opportunities
David RockcliffeProgram Director
Molecular and Cellular Biosciences
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Outline
• Overview of NSF– Where we are
– What we do
– How we are organized
• Types of funding opportunities
• Submitting proposals
• Proposal review process
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is the NSF?
We are here
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NSF
NIH
VAMD
DC
Where is the NSF?
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NIH
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• Created in 1950 as an independent federal agency
• Budget $6.9 billion (2010)• Supports ~20% of federally-funded
basic research in colleges and universities
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NSF Mission• Strengthen connections between discovery and technological innovation
• Modernize U.S. research and education infrastructure
• Position U.S. to benefit from global science and engineering investments
• Broaden participation, diversity and inclusiveness
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Subra Suresh Cora Marrett
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Evolutionary Processes
Directorate for Biological Sciences
(BIO)
Division of Environmental
Biology(DEB)
Population andCommunity Ecology
EcosystemScience
Division of Integrative
Organismal Systems(IOS)
BehavioralSystems
Developmental Systems
Neural Systems
ResearchResources
HumanResources
Division ofBiological
Infrastructure(DBI)
Division of Molecular and
Cellular Biosciences
(MCB)
BiomolecularDynamics, Structure
and Function
Cellular Processes
Genetic Mechanisms
Effective Nov. 2010
Emerging Frontiers (EF)
Plant GenomeResearch Program
Systematic Biology &Biodiversity Inventories
Physiological & Structural Systems Networks and
Regulation
Joann RoskoskiActing AD
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• Fundamental research on the origins, functions, relationships, interactions, and evolutionary history of populations, species, communities, and ecosystems
– Ecosystems Science
– Evolutionary Processes
– Population and Community Ecology
– Systematic Biology and Biodiversity Inventories
Environmental Biology (DEB)
10
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• Research aimed at understanding the living organism ‐‐ plant, animal, microbe ‐‐as a unit of biological organization
– Behavioral Systems
– Developmental Systems
– Neural Systems
– Physiological and Structural Systems
Integrative Organismal Systems (IOS)
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Biological Infrastructure (DBI)Research Resources Cluster• Advances in Biological Informatics (ABI)
• Biological Research Collections (BRC)
• Improvements in Facilities, Communications, and Equipment at
Biological Field Stations and Marine Labs (FSML)
• Instrument Development for Biological Research (IDBR)
• Living Stocks for Biological Research (LSBR)
Human Resources Cluster• Undergraduate Research and Mentoring in Biology (URM)
• Postdoctoral Research Fellowships in Biology
• Research Experiences for Undergraduates (REU)
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Molecular & Cellular Biosciences (MCB) Mission
To support fundamental understanding of life processes at the molecular, sub‐
cellular, and cellular levels.
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Biomolecular Dynamics, Structure and Function Cluster
• Structure and dynamics of biomolecules
• Biomolecular interactions and mechanisms
• Energy transduction: photosynthesis and
biological electron transfer
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Cellular Processes Cluster
• Membrane organization and function
• Organelle biogenesis, maintenance, and
trafficking
• Cytoskeletal dynamics, cell division, and
motility
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Genetic Mechanisms Cluster
• Gene expression and epigenetics
• Chromosome dynamics, DNA replication, repair,
recombination and inheritance
• Evolution of genes and genomes
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Networks and Regulation Cluster
• Signaling and metabolic networks
• The minimal cell, synthetic biology, and the
origins of life
• Environmental interactions and microbial
communities
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Related Programs
•Physics of Living Systems (MPS‐PHY‐PoLS)
•Chemistry of Life Processes (MPS‐CHE‐CLP)
•Biomaterials Program (MPS‐DMR‐BMAT)
•Chemical, Bioengineering, Environmental and Transport Systems (ENG‐CBET)
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http://www.nsf.gov
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Funding Opportunities
• “Regular” research proposals
• Solicitations
• Supplements to active NSF awards
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“Regular” Proposals
• Address questions pertinent to any
research area in division
• Require substantial preliminary data
• Typical project duration: 3‐5 years
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• For non-tenured faculty members who will become the next generation of academic leaders
• Support projects that effectively integrate research and education
• Require substantive preliminary data• 5-year awards with minimum funding
of $100,000 / year
Faculty Early Career Development (CAREER) Awards
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Research in Undergraduate Institutions
• Supports research by faculty members of predominantly undergraduate institutions
•Single-Investigator and Collaborative Faculty Research Projects
•Shared Research Instrumentation and Tools
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Research Coordination Networks (RCN)
• To advance a field or create new directions in research or education
• Two tracks– Research focused on broad research question, specific group or organisms, or technical advances
– Undergraduate biology education focused on improving undergraduate biology curricula
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BIO Supplementary Funding
• For researchers with active NSF awards– Research Opportunity Awards
– Research Experiences for Teachers
– Research Experiences for Undergraduates
– Research Assistantships for High School Students
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Research Opportunity Awards (ROA)
• Support faculty from predominantly undergraduates institutions to participate in ongoing, NSF‐funded research projects
• Goals are to enhance research at both participating institutions and to improve research and teaching at the undergraduate institution
• Duration: summer or semester
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Research Experiences for Teachers (RET)
• For K‐12 or community college teachers
• Provide opportunities for teachers to engage in research, with eventual aim of transferring new knowledge to the classroom
• Typical duration: summer or semester
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Research Experiencesfor Undergraduates (REU)
• Provide undergraduates with research training through hands‐on participation in research, leading to presentations and publications
• Typical duration: 8‐10 weeks in summer
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Research Assistantships for High School Students (RAHHS)
• To foster interest in pursuit of studies in biological sciences
• Targeted at high school students from underrepresented groups
• Typical duration: summer, semester, or academic year
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International Collaborations
• Offer opportunities for collaborations of PI or students with international labs
• Coordinated by your program director and a program director in the Office of International Science and Engineering Program
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The Proposal Cycle
The IDEA
Preliminary Results ProposalPreparation
Merit Review
An AWARD!A Decline
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How to submit a proposal
• Discuss your idea with your program director
• Review submission guidelines (Grant Proposal Guide)
• Cover all the bases– Intellectual Merit and Broader Impacts
– Postdoctoral Mentoring Plan
– Data Management Plan
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Steps in Review Process
• Receipt
• Assignment to a program (or cluster)
• Administrative Review
– Checked for compliance
• Both review criteria addressed
• Post Doctoral Mentoring Plan
• Data Management Plan
• Formatting
• Appropriateness (Disease‐related?)
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Steps in Review Process
• Scientific Review– ad hoc reviews
– Panel review
• Decisions– Award or decline recommendation by Program Director
– Concurrence by Division Director
– Award notifications by Division of Grants and Agreements
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NSF Merit Review Criteria
• What is the intellectual merit and quality of the proposed activity?
– Creativity, originality, potentially transformative concepts
– Potential to advance knowledge and understanding within and across fields
– Conceptualization and organization
– Qualifications of investigators
– Access to resources
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NSF Merit Review Criteria
• What are the broader impacts of the proposed activity?
– Discovery while promoting teaching, training and learning
– Participation of underrepresented groups
– Enhancement of infrastructure for research and education
• Needs to be addressed in both project summary and project description
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Opportunities for You to Get Involved in Review
• Become an ad hoc reviewer
• Become a panelist
• Become a rotating program director
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Questions?