Download - Nano Restorative
-
5/20/2018 Nano Restorative
1/84
Good morning
1
-
5/20/2018 Nano Restorative
2/84
ano Restorative dental
materials
2
-
5/20/2018 Nano Restorative
3/84
INTRODUCTION
Humankind has always been plagued by the problem of restoringparts of the body lost due to an accident or disease. The replacement
of lost teeth is desired for two primary reasons:
Esthetics
Restoration of function (partial or complete).
Restorative dental materials include noble and base metals, amalgam
alloys, cements, composites, glass ionomers, ceramics, denture base
resins, and other materials used in restorative dental operations.
Each material has several advantages and disadvantages.
To overcome the drawbacks of various materials, there has been
continuous research for the advent of newer and better restorative
materials.
3
-
5/20/2018 Nano Restorative
4/84
nanotechnology
The term nanotechnology was coined byProf. Kerie E.Drexler.
Nanotechnology is the engineering ofmolecularly precise structures.
The prefix nano means 10-9or onebillionth of a unit.
4
-
5/20/2018 Nano Restorative
5/84
NANODENTISTRY
Defined as the science and technology ofdiagnosing, treating and preventing oral
and dental diseases, relieving pain,preserving and improving dental healthusing nano-structured material.
5
-
5/20/2018 Nano Restorative
6/84
nanomaterials
Nanomaterials include nanoparticles,
nanoclusters, nano-crystals, nanotubes,nanofibres, nanowires, nanorods,
nanofilms etc.
6
-
5/20/2018 Nano Restorative
7/84
Nanoparticles
Molecular units typically
defined as having diameters ofbetween 0.1 and 100 nm.
Represent the mostwidespread use of nanoscaleunits in dentistry.
They are currently being usedin resin-based compositerestorations (RBC).
Organosilanes such asallyltriethoxysilane, have alsodemonstrated goodcompatibility with nanoparticlefillers, such as TiO2.
7
-
5/20/2018 Nano Restorative
8/84
YbF3 Nano particle
Mono-dispersed powdersproduced by sol-gel reaction
Properties Optical transparency
High radio opacity Low shrinkage
Easy to polish
Safe for patients
Applications Improving radio opacity for X-
ray diagnosis
YbF3lens
Filler for flowable composite
Barium glass & Strontiumglass
Homogeneous composition
Glass powder produced bymelting
Properties Low optical opacity
High radio opacity
Easy to polish
Provides hardening and strength
Easy miscibility with resin
Fine particle size
Application
Composite filler8
-
5/20/2018 Nano Restorative
9/84
Silver nanoparticles
Used as an alternative to dental filling agents.
The unique advantages of these nanoparticles are the anti wear;antibacterial and antifungal properties enable their use inrestorative dentistry.
9
-
5/20/2018 Nano Restorative
10/84
Incorporating silver zeolite in endodontic filling
materials increases the material bactericidal effectagainst some microorganisms.
Composite resins modified by microparticulated silverrevealed antiadherence activity and bactericidal
effect against S. mutans.
The application of nanoparticles to control biofilmformation within the oral cavity, as a function of theirbiocidal, antiadhesive, anti-inflammatory, antiviral, anddelivery capabilities, is worthy of serious consideration
10
-
5/20/2018 Nano Restorative
11/84
The bactericidal activity of silver nanoparticles has
been attributed to mechanisms such as the release ofAg+.
However, according to Chaloupka et al. nanosilver hasintrinsic antibacterial properties that do not depend onthe elution of Ag+.
Silver causes bacterial membrane disruption probablydue to the production of reactive oxygen species,including free radicals.
The active oxygen causes structural damage inbacteria, which is called an oligodynamic action.
Membrane disruption allocates nanosilver particles intocytoplasm causing subsequent damage of DNA andother phosphorus containing compounds, impairing therespiratory chain and cell division .
11
-
5/20/2018 Nano Restorative
12/84
Nanorods Nanorods are of particular
interest in a restorativecontext.
Since they are similar tothe enamel rods that makeup the basic crystallinestructure of dental enamel,nanorods could contributeto a practical artificialapproximation of such anaturally occurringstructure.
Chen et al. have synthesizedenamel prism-likehydroxyapatite (HA)nanorods that exhibit self-
assembly properties. 12
-
5/20/2018 Nano Restorative
13/84
Nanospheres
Nanospheres areexplored inrestorative systems inconjunction with
calcium phosphatedeposition andamelogenin nanochainassembly to mimic thenanoprocesses already
inherent in naturaltooth development.
13
-
5/20/2018 Nano Restorative
14/84
Nanotubes
Titanium oxidenanotubes havebeen shown in vitroto accelerate thekinetics ofhydroxyapatiteformation, mainly ina context of bone-
growth applicationsfor dental implantcoatings.
14
-
5/20/2018 Nano Restorative
15/84
More recently,
modified single walledcarbon nanotubes(SWCNT) have beenshown to improve the
flexural strength ofRBC.
They have silicondioxide applied tothem in conjunctionwith specializedorganosilane bondingagents.
15
-
5/20/2018 Nano Restorative
16/84
Nanofibers
Polymer nanofiberspermit easier additionof surfacefunctionalities compared
to polymer microfibers.
Polymer nanofibermaterials have beenstudied as drug-deliverysystems, scaffolds fortissue engineering, andfilters.
16
-
5/20/2018 Nano Restorative
17/84
More recently, nanofibershave been used to generateceramics containing
hydroxyapatite and fluor-hydroxyapatite.
Nanofibrillar silicate crystalshave also been recently
studied in the reinforcementof dental composites.
Added in the correctproportions and with uniform
distribution of thefibers/crystals, nanofibershave been demonstrated toimprove the physicalproperties of these
composites
17
-
5/20/2018 Nano Restorative
18/84
Dendrimers and dendritic copolymers
Dendrimers and dendritic copolymers have been studied lessextensively than other nanostructures in relation to dentalcomposite applications.
Combinations of specific polymers to optimize efficacy ofrestorative applications have been reported.
18
-
5/20/2018 Nano Restorative
19/84
Nano restorative materials
Various nanostructures are manipulatedtogether to either modify the existingdental materials or produce the newer
better alternatives.
19
-
5/20/2018 Nano Restorative
20/84
Advances in amalgam
based onnanotechnology
20
-
5/20/2018 Nano Restorative
21/84
A NEW DENTAL POWDER FROM
NANOCRYSTALLINE MELT SPUN Ag Sn
Cu ALLOY RIBBONS
A new non-gamma-2 dental powder has been developed
from nanocrystalline melt-spun Ag-Sn-Cu alloy ribbons.The amalgam made from this powder exhibits
excellent properties for dental filling.
The nanocrystalline microstructure was found for the
first time in as-spun and heat treated Ag, Sn, Cu alloyribbons, using X-ray diffraction, scanning electronmicroscopy and energy-dispersive spectroscopy.
21
-
5/20/2018 Nano Restorative
22/84
Structure
As-spun ribbons exhibiteda multi-phasemicrostructure withpreferred existence of(Ag4Sn) phase formed
during rapid solidification(RS) due tosupersaturating of copper(Cu) atoms and homogenousnanostructure withsubgrain size of about 40-
50mm, which seems to bedeveloped during the rapidsolidification process andcan be caused by eutecticreaction of theAg3Sn/Ag4Sn-Cu3Sn
system.
The cross-sectional and top-viewed OM
micrographs of as-spun Ti51Ni49 ribbons.
(a) Cross-sectional view of as-spun
ribbons, (b) top view near the edge of as-
spun ribbons and (c) top view in the
middle of as-spun ribbons.22
-
5/20/2018 Nano Restorative
23/84
In heat treated ribbons the clustering of Cuatoms was always favored and stable in an ageingtemperature and time interval determined by Cucontent.
The heat treatment led to essential changes ofsubgrain morphology, resulted in the appearanceof large-angle boundaries with fine Cu3Sn
precipitates and forming typical recrystallizationtwins.
23
-
5/20/2018 Nano Restorative
24/84
Such a microstructure variation in melt-spunribbons could eventually yield enhancedtechnological, clinical and physical properties of thedental products.
Thus, using the rapid solidification technique a newnon-gamma-2 dental material of high quality,nanocrystalline ribbon powder, can be produced.
24
-
5/20/2018 Nano Restorative
25/84
Advances in glass ionomer
cements based on nanotechnology
25
-
5/20/2018 Nano Restorative
26/84
Nanoparticulated resin modified
glass ionomer cement
Nanoionomer is the latest development in along history of glass ionomer technologydeveloped by 3M ESPE.
Nanoparticulated ionomer is the first resin-modified glass ionomer cement withnanotechnology, combining the benefits of
resin-modified light-cure glass ionomercement (RMGIC) and bonded nanofillerparticles.
26
-
5/20/2018 Nano Restorative
27/84
Advantages
Improved polish and aesthetics,abrasion resistance, strength, optical
properties, and increased fluoriderelease.
In addition, there is also less number of
voids, cracks, and microporosities onthe surface in nanoionomer than theother ionomers available.
27
-
5/20/2018 Nano Restorative
28/84
Ketac
N1 Light CuriNg
Nano Ionomer
Restorative
A nano-ionomeris an aesthetic, fluoride-releasingrestorative solution.
28
-
5/20/2018 Nano Restorative
29/84
Indications
Primary teeth restorations
Small Class I restorations
Class III and V restorations
Filling defects and undercuts
Laminate/Sandwich technique
Core build-up where at least 50% ofcoronal tooth structure is remaining forsupport
29
-
5/20/2018 Nano Restorative
30/84
composition
The nano-ionomer is based on the acrylic and itaconicacid copolymers necessary for glass-ionomer reactionwith fluoroaluminosilicate (FAS) glass and water.
It contains a blend of resin monomers, BisGMA,TEGDMA, PEGDMA and HEMA which polymerize viathe free radical addition upon curing and the primarycuring mechanism is by light activation.
The originality of this glass-ionomer cement is theinclusion of nano-fillers which constitute up to twothirds of the filler content (69 wt%).
30
-
5/20/2018 Nano Restorative
31/84
Nano fillers are further surface modified
with methacrylate silane coupling agents toprovide covalent bond formation into the freeradically polymerized matrix.
The fluoroaluminosilicate glass is radiopaque,has particle size of less than 3 microns
Provides the basis for the glass ionomerreaction and extended fluoride release in the
presence of water and a polycarboxylic acidfunctional polymer.
31
-
5/20/2018 Nano Restorative
32/84
Contains combination of two types of
surface treated nanofillers (5-25 nm) andnanoclusters (1.0 to 1.6 microns).
The methacrylate functionalized nanofillers
in this composition include those chemicallyderived from both silica and zirconia.
The nanocluster fillers are loosely bound
agglomerates of nano-sized zirconia/silicathat appear as a single unit enabling higherfiller loading, radioapacity, and strength.
32
-
5/20/2018 Nano Restorative
33/84
KetacNano Primer
Ketac Nano primer is a one part,visible light-cure liquid specificallydesigned for use with Ketac Nanorestorative.
Comprised of the Vitrebondcopolymer, HEMA, water, andphotoinitiators.
The primer is acidicin nature.
Its function is to modify the smearlayer and adequately wet the toothsurface to facilitate adhesion of Ketac
Nano restorative to the hard tissue. 33
-
5/20/2018 Nano Restorative
34/84
Ketac Nano primer is applied to thesurface for 15 seconds, and air dried.
The primer is then light cured for 10seconds.
Adequately air drying followed by lightcuring of the primer before placement ofKetac Nano restorative provides adhesionto tooth structure.
34
-
5/20/2018 Nano Restorative
35/84
Advantages
Easy to create a high initial gloss andachieve a smooth final surface
Saving time in difficult to polishsituations such as Class V restorations.
Reduces waste, quick delivery of the
material and the right mix every time.
35
-
5/20/2018 Nano Restorative
36/84
Related studies N100 and other glass-ionomer cements from
the Fuji family were compared but KetacN100 showed less porosities and surfacecracks than Fuji materials.
(Markovic et al 2008)
36
-
5/20/2018 Nano Restorative
37/84
A study on bonding orthodontic bracketsshowed significantly lower shear bondstrength for Ketac N100 compared to aconventional light-cure orthodontic bondingadhesive (Transbond XT).
However, it has been suggested that thisnano-ionomer may be used for bondingorthodontic brackets since the obtained shearbond strength is within clinically acceptable
range.(Uysal et al. 2009)
37
-
5/20/2018 Nano Restorative
38/84
Another study using the shear bond strength asan adhesion parameter showed that Er:YAGlaser dentine pre-treatment results in lowerbond strength values compared to acid etchingor a combined acid-etching and laser pre-treatment.
(Korkmaz et al. 2009)
A study on microleakage around Class V cavitiesshowed that Er:YAG preparation results ingreater microleakage than a conventional cavitypreparation with a bur when a nano-ionomer
(Ketac N100) and a nano-composite (FiltekSupreme XT) were used as restorativematerials.
(Ozel et al. 2009)
38
-
5/20/2018 Nano Restorative
39/84
In a study by Leuven BIOMAT Research Cluster ithas been concluded that Ketac N100 bonded aseffectively to enamel and dentin as a conventionalglass-ionomer (Fuji IX GP), but bonded lesseffectively than a conventional resin-modified glass-
ionomer (Fuji II LC). Its bonding mechanism should be attributed to micro-
mechanical interlocking provided by the surfaceroughness, most likely combined with chemicalinteraction through its acrylic/itaconic acid
copolymers.(Coutinho et al. 2009)
39
v
-
5/20/2018 Nano Restorative
40/84
Advances in composites
based on nano
technology
40
-
5/20/2018 Nano Restorative
41/84
Nanocomposites
Nanoproducts Corporation hassuccessfully manufactured non-
agglomerated discrete nanoparticlesthat are homogeneously distributed in
resins or coatings to produce
nanocomposites.
41
-
5/20/2018 Nano Restorative
42/84
composition
The nanofiller used include analuminosilicate powder having a meanparticle size of 80nm and a 1:4 M ratio
of alumina to silica and a refractiveindex of 1.508.
42
-
5/20/2018 Nano Restorative
43/84
Advantages
Superior hardness
Superior flexural strength, modulus ofelasticity and translucency
50% reduction in filling shrinkage
Excellent handling properties
43
-
5/20/2018 Nano Restorative
44/84
Filtek O supreme universal restorative
pure nano O
44
-
5/20/2018 Nano Restorative
45/84
PROPERTIES
Mechanical strength and wear resistance : Provided by the filler particles. Similar to hybrid composites.
Superior polish and gloss retention similar to microfillcomposites.
Flexural strength: Depends on the filler content and filler chemistry.
Flexural strength of nanocomposites were found to be
statistically equivalent or higher than those of the hybrid ormicrohybrid composites and significantly higher than those ofthe microfill composites.
Nanofill composites, which have higher filler loading, showgreater flexural strength than nanohybrid composites, which
have lesser filler loading. 45
-
5/20/2018 Nano Restorative
46/84
Polymerization shrinkage:
Low shrinkage due to the low shrinkage epoxy resinand strong interfacial interactions between resin andnanoparticles.
The volumetric shrinkage depends on the totalcontent of organic matrix of composites.
Nanohybrid composites (Grandio) showed leastamount of organic matrix (13.0 wt-%) and leastshrinkage when compared to nanofill composites(Filtek Supreme Translucent), which had 30.0 wt-%organic matrix.
Polymerization shrinkage also depends on thechemistry of the organic matrix.
46
-
5/20/2018 Nano Restorative
47/84
Water Sorption:
Water uptake in the polymeric phase of compositescauses the solvent to extract unreacted components,mainly monomer, resulting in shrinkage, loss of weight,and reduction in mechanical properties.
Conversely, solvent uptake leads to a swelling of thecomposite and increase in weight. The solventdiffuses into the polymer network and separates the
chains creating expansion.
Nanohybrid composites show less water sorption thannanofill composites.
47
-
5/20/2018 Nano Restorative
48/84
Wear and gloss retention:
The nano-sized primary particles in the nanoclusterswear by breaking off individual primary particles
rather than plucking out the larger secondaryparticles from the resin. Thus resulting wearsurfaces have smaller defects and better glossretention as that of a microfilled composites.
48
-
5/20/2018 Nano Restorative
49/84
Nanohybrid composite restorations
The evolution of composites initially created two families ofmaterials:
Microfilled composites :
Smaller particle fillers
Better polish retention
Enhanced aesthetics
Less strength. Chosen primarily for esthetic-
driven anterior restorations.
Hybrid composites :
Larger particle fillers
Improved strength
Less polishable
Chosen for their durability for
posterior restorations. 49
-
5/20/2018 Nano Restorative
50/84
The latest generation ofnanohybrid composites,combine the best of both
materials and create durablerestorations that maintain agloss shine for many years.
Important for maximizedesthetics, as well as reducedplaque accumulation.
The clinical success ofhybrids, such as Tetric andHerculite, has paved the way
for development of theirnanohybrid siblings.
These include Premise andHerculite Ultra.
50
-
5/20/2018 Nano Restorative
51/84
Advantages
1) Minimal removal of tooth material: Adhesive properties allowadding material to defective areas without the need foradditional preparation.
2) Expenses associated with lab fees and multiple appointmentsincrease the cost of lab-processed restorations. Directnanohybrid composite restorations, on the other hand, canresult in cost savings when provided in lieu of crowns.
3) Nanohybrid composite restorations are completed in oneappointment, this saves time and inconvenience required for aseparate cementation appointment.
51
-
5/20/2018 Nano Restorative
52/84
4) Can be polished to a high- gloss finish whichensures optimum esthetics resembling natural
teeth with minimal plaque accumulation.5) Ease of color matching maximizes estheticresults. The material blends seamlessly intothe teeth being restored, showing no evidenceof the repaired area and without lookingprosthetic.
6) Nanohybrids create more tools to solvemultiple problems for patients. When stressfactors are favorable, immediate single-toothreplacement can be accomplished with directcomposite bonding without the need to removeadditional tooth structure.
52
-
5/20/2018 Nano Restorative
53/84
Fusion Ceramfil
Aesthetic, syringeable, sculptable, radiopaque, highly
filled nano-hybrid composite for the restoration of allteeth.
Cured at a wavelength of 400 - 500 nm (blue light).
53
-
5/20/2018 Nano Restorative
54/84
Fusion Ceramfilis
available in followingVITA shades: A1,A2, A3, A3.5, A4,B1, B2, B3, C2,C3
etc.
Packaging:
1 x 4g Refill packs
54
-
5/20/2018 Nano Restorative
55/84
Composition
The fillers consist of barium glass fillers,
radio-visible fillers and silicone dioxide with aparticle size between 0.04 and 3 m.
The inorganic fillers amount to a portion of80% (w/w).
Methacrylates (22% w/w). It comprises additives, prepolymer, initiators,
stabilizers and dyes (0.8% w/w).
55
-
5/20/2018 Nano Restorative
56/84
IndicationS
Universal inlay material for direct restorationof cavities of anterior and posterior teeth(also occlusal stress bearing)
Class III and IV anterior tooth inlays
Class V inlays (cervical caries, root caries,wedge-shaped defects) Class I and II posterior area inlays Veneering for discoloured anterior teeth
Fixation of loose teeth Fissure sealing in the molar and posterior area Repair of composite and ceramics veneers
56
-
5/20/2018 Nano Restorative
57/84
Application
Colour selection: Prior to colour determination,the tooth should be cleaned and polished andthe tooth be moist.
Cavity preparation
Pulp protection/lining:For very deep areas near the pulp,introduce a calcium hydroxide preparation, then overlay
with pressure-resistant cement. The cavity walls should notbe covered since they will be needed for bonding withenamel/dentine adhesive.
57
-
5/20/2018 Nano Restorative
58/84
Enamel
and
Dentine
conditioning
Bonding:
Follow the manufacturer'sinstructions for the use of theproduct applied. Application
of Fusion Ceramfil is introduced ata layer thickness of no more than 2
mm and shaped using a suitableinstrument. Each layer is cured with
a light lamp for 40 seconds. Indoing so, the light conductor is held
as close to the material as possible.If metal dies were used, the buccal
or lingual/palatinal sides,respectively, should be light-curedonce more after removal of the die
Completion of therestoration:
After light-curing, excessmaterial is removed usingsuitable finishers or fine
diamond grinders. Controlocclusion and articulation
and adapt if necessary.Finally, polish to high gloss
using silicone polishers,disks or stripes
58
-
5/20/2018 Nano Restorative
59/84
Storage
Do not use Fusion Ceramfil afterthe indicated date of expiration.
Storage temperature (28 C / 82
F). Close syringe immediately after
use. Store material protected from
light. Shelf life: see date of expiration.
59
-
5/20/2018 Nano Restorative
60/84
If necessary,Fusion Ceramfilmay be
applied directly to cured material. If theinlay has been polished before, it shouldbe roughened first, and bonding should beapplied to the surface prior to applyingnew Fusion Ceramfil.
Fusion Ceramfil should be used at roomtemperature only (not at temperaturesexceeding 28 C). At lowertemperatures, the material is more
difficult to squeeze out.
60
Ormocer
-
5/20/2018 Nano Restorative
61/84
Ormocer Acronym for organically modified ceramics.
Represents a new technology based on Sol gelsynthesis using particles comprising silicones organicpolymers and ceramic glass.
61
-
5/20/2018 Nano Restorative
62/84
Ormocer (VOCO Gmbh, Germany) compositetechnology is used in conjunction will nanoparticlefillers such as ZnO2 that are widely used innanocomposite restorative systems.
62
polyhedral oligomeric silsesquioxane
-
5/20/2018 Nano Restorative
63/84
polyhedral oligomeric silsesquioxane
(POSS)25 molecule
Can be used in dental applications to:
(a) Improve adhesion at the interface
between the restorative material and thetooth structure;
(b) Reduce tooth sensitivity through sealingthe tubules with POSS nano-sized
molecules.(c) Provide structural reinforcement,
toughness and processability.
63
-
5/20/2018 Nano Restorative
64/84
64
Nano-sized CaPO4-incorporated
-
5/20/2018 Nano Restorative
65/84
Nano sized CaPO4 incorporated
composites
Used in the optimaldelivery of moleculesthat facilitate toothstructureremineralization andforestall caries is anactive area ofnanostructure-basedresearch.
Much of this workinvolves nanoparticles inconjunction with RBCsystems.
A typical
TEM image
showing
hollow CaP
nanoshells
65
-
5/20/2018 Nano Restorative
66/84
Study by Xu et al. evaluated the incorporationof nano-sized CaPO4 particles with RBC, with a
resulting improvement in stress-bearingcapacity, as well as ion release that couldinhibit caries.
Further investigation of this model usingdicalcium phosphate anhydrous incorporatedwith nanosilica-fused whiskers found that itincreased the strength of the RBC by as muchas threefold while releasing CaPO4. Thisrelease was greater with decreasing CaPO4particle size.
The authors hypothesize that such a systemcould provide a desirable combination of cariesprevention and increased restoration strength.
66
-
5/20/2018 Nano Restorative
67/84
Nano-ceramic restorative
materials
67
CeramX
-
5/20/2018 Nano Restorative
68/84
CeramX
Light cured,radiopaquerestorative materialwith improvedorganically modifiedCeramic particles,resulting in a Nano-Ceramic Restorativewith unique features.
Natural aesthetics,low monomer releaseand superior handlingcharacteristics.
68
Ceram X provides two shading
-
5/20/2018 Nano Restorative
69/84
CeramX provides two shadingsystems:
CeramXmono: Single
Translucency System, comprisesseven shades of intermediatetranslucency comparable toconventional composites (e.g.SpectrumTPH), optimal forfast and easy restorations ofposterior or anterior teeth.
CeramXduo: DoubleTranslucency System, offersfour dentin shades withtranslucencies of natural dentinand three enamel shades whichmimic natural enamel.Additionally, CeramX duocomprises one bleach dentineshade for the restoration ofbleached teeth.
69
-
5/20/2018 Nano Restorative
70/84
The CeramX restorative system isavailable in predosed Compules tips
and Easy-Twist syringes.
70
COMPOSITION
-
5/20/2018 Nano Restorative
71/84
COMPOSITION
Methacrylatemodified polysiloxane
Dimethacrylate resin
Fluorescence pigment UV stabilizer
Stabilizer
Camphorquinone Ethyl-dimethylamino
benzoate
Barium-aluminium-borosilicate glass
Methacrylate
functionalised silicondioxide nano filler
Iron oxide pigmentsand titanium oxide
pigments Silicate pigments
according to shade
71
-
5/20/2018 Nano Restorative
72/84
Indications:
Direct restorations of all cavity classesin anterior and posterior teeth.
Contraindications:
Known allergy to methacrylate resins orany other of the components.
72
-
5/20/2018 Nano Restorative
73/84
WARNINGS:
CeramX contains methacrylates which may beirritating to skin and eyes.
In case of contact with eyes, rinse immediately withplenty of water and seek medical advice.
Do not take internally.
CeramX contains polymerizable monomers which maycause skin sensitization (allergic contact dermatitis) insusceptible persons. Wash thoroughly with soap and
water after contact. If skin sensitization occurs, or ifa known allergy to methacrylate resin exists,discontinue use.
73
INTERACTIONS WITH OTHER DENTAL
-
5/20/2018 Nano Restorative
74/84
INTERACTIONS WITH OTHER DENTALMATERIALS
Eugenol and hydrogen peroxide containingdental materials should not be used in
conjunction with these products because theymay prevent setting and cause softening ofthe polymeric components of the material.
74
Esthetic materials
-
5/20/2018 Nano Restorative
75/84
Esthetic materials
With the combination of finishing and
polishing procedures, a nanotechnologyliquid polish application might provide amore glossy surface for resin composite
restorations.
75
-
5/20/2018 Nano Restorative
76/84
Lasting Touch Nano Technology
Liquid Polish
Light cured resinmaterial.
When applied to curedrestorative materials
creates a smooth highluster finish retainedover time in thepresence of oral
abrasions. Seals the margins of
composite restorations.
Better wear and stain
resistance. 76
Solutions
-
5/20/2018 Nano Restorative
77/84
Solutions
Nanosolutions produce unique
and dispersible nanoparticles,which can be used in bondingagents.
Ensures homogeneity and
ensures that the adhesive isperfectly mixed every time.
10% 5 nm spherical silica isused as the filler.
Adper O single bond plusadhesive single bond.
77
NANO-BOND ADHESIVE
-
5/20/2018 Nano Restorative
78/84
NANO BOND ADHESIVE
Nano-Bond Nano-ParticulateReinforced Adhesive is a 6thgeneration self-etch bondingsystem that virtuallyeliminates sensitivity.
Can be used for direct orindirect bonding applications.
Consists of a uniquelyformulated self-etch primerand a nano-particulate
reinforced adhesive thatwork together to producetenacious bond to the tooth.
78
Materials for endodontic
-
5/20/2018 Nano Restorative
79/84
Materials for endodontic
regeneration based on
nanotechnology
Teeth with degenerated and necrosed pulps areroutinely saved by root canal therapy.
Although current treatment modalities offer highlevels of success for many conditions, an ideal formof therapy might consist of regenerative approaches,in which diseased or necrotic pulp tissues areremoved and replaced with healthy pulp tissues torevitalize teeth.
79
Fioretti et al showed that
-
5/20/2018 Nano Restorative
80/84
Fioretti et al. showed thata-MSH (melanocortinpeptides) possess anti-
inflammatory propertiesand also promote theproliferation of pulpalfibroblasts.
They reported the firstuse of nanostructured andfunctionalized multilayered
films containing a-MSH as anew active biomaterial forendodontic regeneration.
80
Nano odontology: nanostructured
-
5/20/2018 Nano Restorative
81/84
assemblies for endodontic regeneration
Nano-odontology provides a suitable solutions for pulp tissue
conservative and regenerative approaches. The objective was to use nanostructured assemblies
containing DGLG4 and PGA-alpha-MSH to design a newnanomaterial.
These nanostructured assemblies (DGLG4-PGA-alpha-MSH)n
constitute a thick reservoir of the anti-inflammatorypeptide and promote adhesion and proliferation of pulpfibroblast on the biomaterial surface.
These nanostructured films could be adapted for anendodontic regeneration application to target pulpconnective tissue regeneration, reduction of inflammation by
using PGA-alpha-MSH and initiation of the regeneration ofthe connective tissue by the nanostructured film.
J Biomed Nanotechnol.2011 Jun;7(3):471-5 81
http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492 -
5/20/2018 Nano Restorative
82/84
Conclusion Nanotechnology will change dentistry, healthcare, and human life more
profoundly than many developments of the past.
As with all technologies, nanotechnology carries a significant potentialfor misuse and abuse on a scale and scope never seen before. However,they also have potential to bring about significant benefits, such asimproved health, better use of natural resources, and reducedenvironmental pollution.
Current work is focused on the recent developments, particularly ofnanoparticles and nanotubes.
The materials developed such as the hollow nanospheres, core shellstructures, nanocomposites, nanoporous materials, and nanomembranes
will play a growing role in materials development for the dental industry.
82
refrences
-
5/20/2018 Nano Restorative
83/84
refrences
Hassan Korbekandi and Siavash Iravani. Silver Nanoparticles . TheDelivery of Nanoparticles.
Rita Chandki et al. NANODENTISTRY: Exploring the beauty of
miniature. J Clin Exp Dent. 2012;4(2):e119-24.
Jyoti Gupta. Nanotechnology applications in medicine and dentistry.
Journal of Investigative and Clinical Dentistry (2011), 2, 81
88. Anna V. Rybachuk, Ivan S. Chekman, Tetyana Yu. Nebesna.
Nanotechnology and nanoparticles in dentistry.
Sneha S. Mantriand Shivkumar P. Mantri. The nano era in dentistry. Nat
Sci Biol Med. 2013 Jan-Jun; 4(1): 3944.
Fioretti F et al. Nano-odontology: nanostructured assemblies for
endodontic regeneration.J Biomed Nanotechnol.2011 Jun;7(3):471-5.
T.S.V Satyanarayana and Rathika Rai Nanotechnology: The future.
Journal of Interdisciplinary Study. 2011; 1(2): 93-100.
83
http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SS[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SP[auth]http://www.ncbi.nlm.nih.gov/pubmed?term=Fioretti%20F[Author]&cauthor=true&cauthor_uid=21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.jidonline.com/searchresult.asp?search=&author=T.S.V+Satyanarayana&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=Rathika+Rai&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=Rathika+Rai&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=Rathika+Rai&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=Rathika+Rai&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=Rathika+Rai&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=T.S.V+Satyanarayana&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=T.S.V+Satyanarayana&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=T.S.V+Satyanarayana&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=T.S.V+Satyanarayana&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=T.S.V+Satyanarayana&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=T.S.V+Satyanarayana&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.jidonline.com/searchresult.asp?search=&author=T.S.V+Satyanarayana&journal=Y&but_search=Search&entries=10&pg=1&s=0http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed/21830492http://www.ncbi.nlm.nih.gov/pubmed?term=Fioretti%20F[Author]&cauthor=true&cauthor_uid=21830492http://www.ncbi.nlm.nih.gov/pubmed?term=Fioretti%20F[Author]&cauthor=true&cauthor_uid=21830492http://www.ncbi.nlm.nih.gov/pubmed?term=Fioretti%20F[Author]&cauthor=true&cauthor_uid=21830492http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SP[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SP[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SP[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SP[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SP[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SP[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SS[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SS[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SS[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SS[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SS[auth]http://www.ncbi.nlm.nih.gov/pubmed/?term=Mantri%20SS[auth] -
5/20/2018 Nano Restorative
84/84
Thank you